LOCUS       DAVDHZ010000001       117219 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000001 DAVDHZ010000000
VERSION     DAVDHZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 117219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 117219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..117219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.001"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            204..872
                     /locus_tag="VUR46_000001"
     CDS             204..872
                     /locus_tag="VUR46_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET5455518.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(1127..1662)
                     /gene="queF"
                     /locus_tag="VUR46_000002"
                     /pseudo
     CDS             complement(1127..1662)
                     /gene="queF"
                     /locus_tag="VUR46_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
     gene            complement(1967..2281)
                     /gene="trxA"
                     /locus_tag="VUR46_000003"
     CDS             complement(1967..2281)
                     /gene="trxA"
                     /locus_tag="VUR46_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET5455519.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTADQIKAIVAE
                     LS"
     gene            complement(2297..2518)
                     /locus_tag="VUR46_000004"
     CDS             complement(2297..2518)
                     /locus_tag="VUR46_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET5455520.1"
                     /translation="MIEITYLDASKNERTVTFDSYEDFDRSQQACLIGVADYYPVQKL
                     TYKGYDLDYHGTYGDVFFYLMKQDLSQYN"
     gene            complement(2616..2996)
                     /locus_tag="VUR46_000005"
     CDS             complement(2616..2996)
                     /locus_tag="VUR46_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5455521.1"
                     /translation="MTYLEKWFDFNRRQKEIETLLEDTIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTSD
                     GQKTLASLQKAVETSLETGLDFLI"
     gene            complement(3139..3990)
                     /locus_tag="VUR46_000006"
     CDS             complement(3139..3990)
                     /locus_tag="VUR46_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET5455522.1"
                     /translation="MSISQRTTKLILATCLACFLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFFLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEALK
                     LVYLDHSDHLFHQTDYHIHYFEMRQRQRRILRNMAQQINTCHLAVSESLILAQLFSKI
                     AGQLSQTNPASDLLDEIERYLEVFRNRSLPKTRDEFETRATLLQLLREAKTFIQVKVD
                     FYQKYGQ"
     gene            complement(4058..5263)
                     /gene="sstT"
                     /locus_tag="VUR46_000007"
     CDS             complement(4058..5263)
                     /gene="sstT"
                     /locus_tag="VUR46_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HET5455523.1"
                     /translation="MKRIIHAWNKASLVKRILIGMLCGGILGLTLPNLSGIGLLGDLF
                     VGGLKAVAPILVFALVANALSQHQKGQDSNMKTVVLLYILGTFAAALVAVVASFIVPI
                     EITLNSANTEIAPPDGIGQVLSNLLLKLVDNPVNALITANYIGILSWAVVFGIAMREA
                     SKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGIGSPANYGILLVLLVT
                     TMLFVALVVNPLIAFFFMRRNPYPLVWNCLRVSGVTAFFTRSSAANIPVNMKLCHDLG
                     LNPDTYSVSIPLGSTINMAGAAITINVLTLAAVNTLGIPVDFATAFVLSVVAAISACG
                     ASGIAGGSLLLIPVACSLFGISNDIAIQVVGGGFVIGVIQDSCETALNSSTDVLFTAV
                     AEYAAARKK"
     gene            5402..5962
                     /locus_tag="VUR46_000008"
     CDS             5402..5962
                     /locus_tag="VUR46_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET5455524.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVNPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            6019..6927
                     /locus_tag="VUR46_000009"
     CDS             6019..6927
                     /locus_tag="VUR46_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET5455525.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            6879..7469
                     /locus_tag="VUR46_000010"
     CDS             6879..7469
                     /locus_tag="VUR46_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET5455526.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYMPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIRIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            7472..8578
                     /gene="yqeH"
                     /locus_tag="VUR46_000011"
     CDS             7472..8578
                     /gene="yqeH"
                     /locus_tag="VUR46_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET5455527.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFISGNDV
                     LLVGNKKDILPKSVKSGKISQWIMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPRTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASTFYDKHLGTLLTPPNSKEKEDFPRLVQRVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVIRKAII"
     gene            8792..9103
                     /gene="yhbY"
                     /locus_tag="VUR46_000012"
     CDS             8792..9103
                     /gene="yhbY"
                     /locus_tag="VUR46_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET5455528.1"
                     /translation="MSLTSKQRAFLNSQAHILKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            9155..9784
                     /locus_tag="VUR46_000013"
     CDS             9155..9784
                     /locus_tag="VUR46_000013"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET5455529.1"
                     /translation="MAIELLTPFTKVELEPEIKEKKRKQIGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIEGLAIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            9784..10377
                     /gene="yqeK"
                     /locus_tag="VUR46_000014"
     CDS             9784..10377
                     /gene="yqeK"
                     /locus_tag="VUR46_000014"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET5455530.1"
                     /translation="MAYQDYINCSREALLEKMAELLPEKRLTHCLGVELAAIELAERF
                     GVDVEKAGLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LNLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETVHTVEHLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            10378..10728
                     /gene="rsfS"
                     /locus_tag="VUR46_000015"
     CDS             10378..10728
                     /gene="rsfS"
                     /locus_tag="VUR46_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET5455531.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIADNIREKVAQAGFKGSHIEGDATGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEAHSVDLSETL"
     gene            10941..11687
                     /locus_tag="VUR46_000016"
     CDS             10941..11687
                     /locus_tag="VUR46_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5455532.1"
                     /translation="MIMATYETFAAVYDEVMDDSLYDKWTDFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRAASAKQKIDFMEGNMLDLSKAGQ
                     YDFVTCYSDSICYMQDEVEVGDVFQEVYNVLNEDGVFIFDVHSTYQTDEIFPGYSYHE
                     NAEDFAMLWDTYEDAAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEVLTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSARWFFVAQK"
     gene            11697..12794
                     /locus_tag="VUR46_000017"
     CDS             11697..12794
                     /locus_tag="VUR46_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET5455533.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLEQAEGLKVVAMSGNFMQRGEPAI
                     IDKWIRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDTLAFGTEEVLD
                     YQKIADLYTEQEAEMEKFVEKLPDSLSYPQKTQAMWKEFADLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVDKDVDFASATALRQHQSDQDFLERFMPSVALFEQA
                     SKVSWDDYFPMLRYQILSNSDLTTIYQVNQEMAVRIKEAIKPAQSVEDLVKVVATKRY
                     TKARVRRLLTYILVQVRESDLSEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDT
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            12926..13180
                     /locus_tag="VUR46_000018"
     CDS             12926..13180
                     /locus_tag="VUR46_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET5455534.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIVQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            13184..13438
                     /locus_tag="VUR46_000019"
     CDS             13184..13438
                     /locus_tag="VUR46_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HET5455535.1"
                     /translation="MLLKFTEDAWADYCYWQTQDKKTLKRINKLIKDIQSDSFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSIAFLSFKDHY"
     gene            13654..15762
                     /locus_tag="VUR46_000020"
     CDS             13654..15762
                     /locus_tag="VUR46_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009659312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET5455536.1"
                     /translation="MSSFKEKLPLFQANDIQISNDVNTVWSIANTLRGAYRADKYRDV
                     IIPMFVLTRLEAALLPTKDQVVAQYKANPNTPEKVLEKLSGYRYYNVSPFTLENLQND
                     PNAIEENFIAYLDGYSCRVKDIIENLKFKEQVRTLAQSGRLFTVIKKFSQIDLSPSSV
                     DSMRMGYMFEDIIRRFSENEEAGSHYTPREVIALMVNLLLIEADEELFVDKKELKILD
                     MAAGTGGMLATAKSYIRQLNTGATARLFGQEVLPETFGIGRADMLIRQEDSDYFVKVD
                     TLKDPDPFPDTKMSFVIANPPFGQAWGGKDADDGVEDAVKKDHQLFDKTEGRQGRFVA
                     TPGTGDAQLLFHLHALTKLEENGRAAIISNGSPLFSGGTSSGESQIRRYILENDLLEA
                     IVALPGQFFYNTGIGIYIWIYNKNKSPERQNKVQFIDATEEFIPLRKSLGQKRRELSQ
                     DNIRQILRWYDDFQENDHVKIFENQEFLYREFTVMQPLQRRGQISEETIEKAKSVPFL
                     AKLFDEYKYQELLEMEPRSAKDEKKLQDFVAGKIKQEAILTALAKGSSDKTYPDFENF
                     VQVIKDLLGEFKLTPANINALALAMSEMDKTAEVIRTKKKDKANEIADGIVYDKTTKD
                     SEIVKLTEDVETYFAREVYPHVPDAHYWFDEEKGYGAEIPFTRYFYQYQEPESAEKLL
                     AEFYALEAELQTLLEELKHD"
     gene            15755..17026
                     /locus_tag="VUR46_000021"
     CDS             15755..17026
                     /locus_tag="VUR46_000021"
                     /inference="COORDINATES: protein motif:HMM:NF013579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5455537.1"
                     /translation="MTRMKESGIDWIGQIPEEWVISKIKFTTQLNGRIGWQGLTSAEY
                     KEEGPYLITGTDFYNGAINFETAVHIDEKRWSEASQIQVENGDLLITKDGTVGKVAII
                     SGLDDKASLNSGVLRIQTVDEIDRKFLYLVLLSDEFWMWFNYTNSGASTILHLYQNVF
                     DEFTFTFPSKNEQQKIADFLDKKTAQLDKVKALLEEQIQKLKDYRASLIYETVTKGLD
                     KNVPMKDSGIDWIGQVPEGWEISKIRYLVTTRSEKRITDSSIPYIGLENIESQTGKFV
                     ETGIQVDKSENIVVEIGDVLFGKLRPYLRKYWRATFPSTASSEFLVFQSSELDMNFLY
                     YAIQSDSFIEEVNTSTYGSKMPRASWEYIKNMKITFPSSLVEQQKIANLLDENTAQID
                     NLIQIKNQQIKNINKQRQTLIYDYVTGKRRV"
     gene            17029..17712
                     /locus_tag="VUR46_000022"
     CDS             17029..17712
                     /locus_tag="VUR46_000022"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455538.1"
                     /translation="MLFGTDLKFRLAYFFTAFFPAFLLIYFSLVDIHHFLLKETESLP
                     CYLSRNLWHFLMLSVLLSIMLISIYSIRGYINGRRSEENIVKNIVLNFNVFKVTLKNN
                     SQGKVIDIQDGPKINPGFISFVSSTIVPSLVLKFMNGVSALVAIIIIVFFFVLLMLSN
                     DIFPNLILPIFGVNLLVTKDNYNIFFFRKDSAAFSGVKRICTLGNTGTMARTFVFFDQ
                     EVLNDEIGE"
     gene            17714..18715
                     /locus_tag="VUR46_000023"
     CDS             17714..18715
                     /locus_tag="VUR46_000023"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455539.1"
                     /translation="MVEIYAIGWQVGRGKSLGKLKNFRKVISDEASNYIGNIQFANNQ
                     NSNESTLTLKEKFEESIESLQNVETNGNNTEVPFYRKIDESLQSEIDRIQLVSSQLET
                     DLPPLKNFEDIRLYLVCEEIDGVQYKYFLKSIRVAKLKTRFIATLTSGKVKIVDIEKD
                     EGRSLPFIISYAEKTENNETIQYIFDVQDYEIMFGLNESKIITAEENYKKFLSHNFKL
                     STDFKVKVSDEESEKIKAKLKSHRKLINLLAKYNDEASSYEWKCVKRANKLSAQFFQT
                     PFTFNEKSKEIYLTAESLEAFISVITNAKKLGIAKNEYEDSLADKRQKDKKDNIEVQ"
     gene            18823..21810
                     /locus_tag="VUR46_000024"
     CDS             18823..21810
                     /locus_tag="VUR46_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HET5455540.1"
                     /translation="MANLGLKERYDFQQWIIKDLRDKNDYIQRDATCYDPRLAMDVEL
                     LWDFLMETQEETMDYLLKKLSKETIVNLINKEIVKGGFLFALKEGVFIENKQLRLLYR
                     KPATSFNEKAVQQYQVNCLSIMEEVVYEESDRIDLVIFINGLALFAIELKFNPSGQSV
                     QDAIRQLKGRNPKNRLFRFEQGVLASFAVDTLEVYMTTQLKGQETYFLPFNVGKGEGI
                     EMGSGNPHNPDGVDTDYLWLDVLTKDSILQLIDSFIFFEMDEMDKHNSKKKTLIFPRY
                     HQRRAVSRLLEDMKVNHTDSNYLIQHSAGSGKTNTIAWLAHSLVSLHDEQNQNIVDTV
                     LIVTDRIVVDRQLQEAVKEISHKPGVVKVMGDKETSSDLADAIAGNTKIIATTIHKFA
                     QINQSNWMSVGNTAKKKFAILIDEAHSSTTGSYMSSVSQVLTETDTEDGTIDEIQEVS
                     VADAIEQEIARTGKQDNVSIIAFTATPKATTLQLFGTTQADGSKAPFDVYSMKQAIEE
                     GFILDVLDNYTTYKTYYKLNKAVEEDPELKTTLAKRKIAKFVELSDENINQKVEIIMD
                     HFISHDIMAELGGQGKAMIVTSGREAAVKYQLAFQKYFKDHSITSIGTLIAFSGKVDY
                     QGSEYTESQMNQVKEDYLKDHFDTEDYQILIVANKYQTGFDQPKLVAMYVDKKLRSVA
                     AVQTLSRLNRIYRGYNKRIFILDFKNTYDDIRSAFSPYYRETILADTVTPSDVLTLDR
                     KIDEYGILDSDVIHEFNQFLYQEKRNSREKQKMVSLLNQGYDRVRRFDEKEQLSIRKV
                     IRGFLRMYTFLIQATAYQNEVLHERYNYLQSLVKMIDVRIGGDDFTIADKIVVDYMKH
                     KQTGSFRSVSELEYHPELILTKPSTGGVTTDQEKRLSEILDEINEQLDLDIDPQVGLS
                     GAVSIRELMKKNPRLKQSARVNSREDFVFAFEEEIDNALIEGYSQSQDLFGALLNNDS
                     FKKRLADIFIDDVFKSLKGSEEV"
     gene            21934..23547
                     /locus_tag="VUR46_000025"
     CDS             21934..23547
                     /locus_tag="VUR46_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET5455541.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERRKEAE
                     LERIGALSQAEARDIILAQTEENLTKEIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            23677..24303
                     /gene="gmk"
                     /locus_tag="VUR46_000026"
     CDS             23677..24303
                     /gene="gmk"
                     /locus_tag="VUR46_000026"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET5455542.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQERLVGRGTDSAEVVAQRIEKAKEEIALM
                     REYDYAIVNDQVSLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            24328..24642
                     /locus_tag="VUR46_000027"
     CDS             24328..24642
                     /locus_tag="VUR46_000027"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET5455543.1"
                     /translation="MMLKPSIDTLLDKVTSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            24708..27104
                     /locus_tag="VUR46_000028"
     CDS             24708..27104
                     /locus_tag="VUR46_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET5455544.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDEEEMEQDLKDIAEVLDFSPVLTQEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHVQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGTLDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLCYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGLTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            27117..28052
                     /locus_tag="VUR46_000029"
     CDS             27117..28052
                     /locus_tag="VUR46_000029"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET5455545.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELIKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            28045..29358
                     /gene="rsmB"
                     /locus_tag="VUR46_000030"
     CDS             28045..29358
                     /gene="rsmB"
                     /locus_tag="VUR46_000030"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET5455546.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKA
                     LVTELVYGTVARRLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            29373..30113
                     /locus_tag="VUR46_000031"
     CDS             29373..30113
                     /locus_tag="VUR46_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET5455547.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            30110..32089
                     /gene="pknB"
                     /locus_tag="VUR46_000032"
     CDS             30110..32089
                     /gene="pknB"
                     /locus_tag="VUR46_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET5455548.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVMKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRKSSDVIAELKEKKVPDNLIKIEEEESSESEPGTIMKQSPGAGTTYDVN
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVSTAPAGTAE
                     GTVVEQSPRAGEKVDLNKTRVKISIYKPKTSSATP"
     gene            32204..32962
                     /locus_tag="VUR46_000033"
     CDS             32204..32962
                     /locus_tag="VUR46_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET5455549.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSIMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGMIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            32964..33413
                     /locus_tag="VUR46_000034"
     CDS             32964..33413
                     /locus_tag="VUR46_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET5455550.1"
                     /translation="MTLTTFLLQAVASLLAIITFLIVLNVQRSMLLPGGILGMAVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGIASGTVILRLYHYIKTHRVS"
     gene            33475..34099
                     /locus_tag="VUR46_000035"
                     /pseudo
     CDS             33475..34099
                     /locus_tag="VUR46_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            34167..34415
                     /locus_tag="VUR46_000036"
     CDS             34167..34415
                     /locus_tag="VUR46_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455551.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QEFVDEMGRTYSGNLILQELITVNEAYKATYIGELYIN"
     gene            34546..35718
                     /locus_tag="VUR46_000037"
     CDS             34546..35718
                     /locus_tag="VUR46_000037"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET5455552.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKNLPQEKKDLLQNHFDHSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTDLSVADYEKVFFEEVDLDETNSAQFAGYENQYFALVEILDHQRRYSKVEK"
     gene            35718..36992
                     /locus_tag="VUR46_000038"
     CDS             35718..36992
                     /locus_tag="VUR46_000038"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET5455553.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEQDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKHVGGFT
                     AQVHQRQMIGQVSLYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSSQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(37028..37993)
                     /locus_tag="VUR46_000039"
     CDS             complement(37028..37993)
                     /locus_tag="VUR46_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5455554.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(37974..39428)
                     /locus_tag="VUR46_000040"
     CDS             complement(37974..39428)
                     /locus_tag="VUR46_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET5455555.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRFQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            39805..41688
                     /locus_tag="VUR46_000041"
     CDS             39805..41688
                     /locus_tag="VUR46_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5455556.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYVSVAPVATGSVSKGDAVIE
                     VKI"
     gene            41837..42724
                     /locus_tag="VUR46_000042"
     CDS             41837..42724
                     /locus_tag="VUR46_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5455557.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(43044..43661)
                     /locus_tag="VUR46_000043"
     CDS             complement(43044..43661)
                     /locus_tag="VUR46_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET5455558.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(44076..44295)
                     /locus_tag="VUR46_000044"
                     /pseudo
     CDS             complement(44076..44295)
                     /locus_tag="VUR46_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(44780..44860)
                     /locus_tag="VUR46_000045"
                     /pseudo
     CDS             complement(44780..44860)
                     /locus_tag="VUR46_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            44976..45869
                     /locus_tag="VUR46_000046"
     CDS             44976..45869
                     /locus_tag="VUR46_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455559.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            45866..47065
                     /locus_tag="VUR46_000047"
     CDS             45866..47065
                     /locus_tag="VUR46_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5455560.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMASRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(47418..48185)
                     /locus_tag="VUR46_000048"
     CDS             complement(47418..48185)
                     /locus_tag="VUR46_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455561.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(48202..48897)
                     /locus_tag="VUR46_000049"
     CDS             complement(48202..48897)
                     /locus_tag="VUR46_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455562.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(48902..49267)
                     /locus_tag="VUR46_000050"
     CDS             complement(48902..49267)
                     /locus_tag="VUR46_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5455563.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     SVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            49407..49880
                     /gene="nrdR"
                     /locus_tag="VUR46_000051"
     CDS             49407..49880
                     /gene="nrdR"
                     /locus_tag="VUR46_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET5455564.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            49881..51050
                     /locus_tag="VUR46_000052"
     CDS             49881..51050
                     /locus_tag="VUR46_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET5455565.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLRHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPISSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKNQAQKSSTPSPAKSNVPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            51051..51947
                     /gene="dnaI"
                     /locus_tag="VUR46_000053"
     CDS             51051..51947
                     /gene="dnaI"
                     /locus_tag="VUR46_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET5455566.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKQASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEELELHFAKGKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            51944..52657
                     /locus_tag="VUR46_000054"
     CDS             51944..52657
                     /locus_tag="VUR46_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET5455567.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            52671..53981
                     /gene="der"
                     /locus_tag="VUR46_000055"
     CDS             52671..53981
                     /gene="der"
                     /locus_tag="VUR46_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET5455568.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIHEQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            54072..54407
                     /locus_tag="VUR46_000056"
     CDS             54072..54407
                     /locus_tag="VUR46_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455569.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            54547..54882
                     /locus_tag="VUR46_000057"
                     /pseudo
     CDS             54547..54882
                     /locus_tag="VUR46_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            55067..55858
                     /locus_tag="VUR46_000058"
     CDS             55067..55858
                     /locus_tag="VUR46_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455570.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLTLVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPITIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAIAYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            55851..56492
                     /locus_tag="VUR46_000059"
     CDS             55851..56492
                     /locus_tag="VUR46_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455571.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FLDYTRKRLVVISKFFTQDLFVWFLGLLPIGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            56496..57146
                     /locus_tag="VUR46_000060"
     CDS             56496..57146
                     /locus_tag="VUR46_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5455572.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            57157..57444
                     /locus_tag="VUR46_000061"
     CDS             57157..57444
                     /locus_tag="VUR46_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455573.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFFPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            57590..60103
                     /gene="secA"
                     /locus_tag="VUR46_000062"
     CDS             57590..60103
                     /gene="secA"
                     /locus_tag="VUR46_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET5455574.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            60184..61215
                     /locus_tag="VUR46_000063"
     CDS             60184..61215
                     /locus_tag="VUR46_000063"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET5455575.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYARRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            61217..62248
                     /locus_tag="VUR46_000064"
     CDS             61217..62248
                     /locus_tag="VUR46_000064"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET5455576.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            62287..62655
                     /locus_tag="VUR46_000065"
     CDS             62287..62655
                     /locus_tag="VUR46_000065"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET5455577.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            62645..63748
                     /locus_tag="VUR46_000066"
     CDS             62645..63748
                     /locus_tag="VUR46_000066"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET5455578.1"
                     /translation="MKASPHRPTKVLIHLGAIRQNIQQMGAHIPQGTLKWAVVKANAY
                     GHGAVAVAKEIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            63767..65782
                     /gene="recG"
                     /locus_tag="VUR46_000067"
     CDS             63767..65782
                     /gene="recG"
                     /locus_tag="VUR46_000067"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET5455579.1"
                     /translation="MNLHQPLHVLPGVGLKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILIDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGKMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVVSYISSIEGWQEDPEWRMIAFHLEKKEHLD"
     gene            66103..67059
                     /locus_tag="VUR46_000068"
     CDS             66103..67059
                     /locus_tag="VUR46_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET5455580.1"
                     /translation="MKNPALLEEMKIYLGRDEVPEDVDAFWDEEVKKVSTLPAYQLEE
                     INFHISQVKCYELTFEGSKQGKVYARVVLPKSEEKVPLIFHFHGYMGRGWDWADMLAF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIIASLPQVDEKRLSSYGASQGGALALVAAALNPRIQKPVAIYPFLSDFRRVLEIGN
                     TSEAYDELFRYFKFYDPFHETEEEIMAILAHRIKGEVKMITGLDDDVCYPITQFAIYN
                     RLTCDKAYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            67912..68139
                     /locus_tag="VUR46_000069"
     CDS             67912..68139
                     /locus_tag="VUR46_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455581.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            68255..71138
                     /locus_tag="VUR46_000070"
                     /pseudo
     CDS             68255..71138
                     /locus_tag="VUR46_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285043.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
     gene            71810..75376
                     /locus_tag="VUR46_000071"
     CDS             71810..75376
                     /locus_tag="VUR46_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HET5455582.1"
                     /translation="MFLYLKGLGKYRKSKAYGLVGCLALVSMIGLAAPDLPVIGGGVV
                     AADVIQGGNDIKDVNVHSKSAEGVAMTYTTYDSGTSGKQTASGSGVFVAPNVMVTVAH
                     NYYDKNQEDKSAVLRGGASARSYVVMNSETEKHNKVPTSGVSETLEKDSIHLYDEKNF
                     GKDYSNDLAVVVTKKTVEAMTGGEDSPRELSHKEVSTGDKISMVGYPNDFSTPNLSAE
                     NKARLKDGKAYSVTTTVSSVNKESGTVTYHSSALGGFSGAPLFNDKGEVVGIHQHGTN
                     TPNAQESERIGGGTLFTEKHRAWIRSMIDKYGIKGWYIDGANRYYYDENHRALKDVES
                     EIDGALYRFDEKGRATLLEGEEKGRVLLRVEDTKGTPLISDKVVQEGSVGSGLNFHLR
                     QNPNFKQLIATSPTAKVVSYNGVPINKLASDTSWSDEYVSKLALGDTIIRAVVDSVTP
                     PSTSSSDFARTEVGKVDLSGKSNLPVPSKEVLQAPNGSENFYATTHIQTPDGSGSGTL
                     IAPNLVLTVAHNFLTVKGSEVVTKSGRTNTVYKATLPSGQPVNFSDDDIVYWNKKDSV
                     FGFKNDLALVRLKEKLTAVSPVEVVSESTSITKGDKVSVYGFPDGRLSPVLDSEVVAT
                     TDFGSGIEGISYGGTKPGASGGGLYNDKGSLIGVHQNGVVGSRSGGLVLSKEQLDWVR
                     SYIEGKPKAPVYVTDNILVDEKDKDKLPSTSKEEKPTTPKVESDKDKPNTPLKPQEKP
                     KTEVITSYEGDSTLEVGKERTEETEGEKEGVSLIYRTVYKGTKSKTEMSPIAFDTVYQ
                     GDETKELGFRSVLEGKEGLVTRTTSYQVDKYTGAVSSKISEEKIAPQSQVITLGIKKN
                     SSTKEVPITERFEDSAELEKGKTEVISEGSVGKEVTTVTYKVLPDGKVIENSRTVDVT
                     PMRERVVRKGVKEVVSPDKVESLVPKDAPIREEQPALSEGFSESDALVSGEKIQGDLG
                     ILIVSSEELVPERVEVPDFVTKVTGGEKLTVEGHRNESKIKTPSKQERSSRPETTAQF
                     TTNGTGSSSLTAVFGGKTDKILLSTVEHSVIKHNQQRGWHKINNQWYFRNSDGKERTG
                     WMKENDAWYYFDTNGTMQTGWLEDTDGNWYYLNDNGRMEIGWFQDSSGAWYYLGSSGR
                     MESNTWIYYKGKWYYIDALGKLLFNSVTPDGYRVNEYGEWIN"
     gene            75653..76564
                     /locus_tag="VUR46_000072"
     CDS             75653..76564
                     /locus_tag="VUR46_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HET5455583.1"
                     /translation="MILRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINRLWTYLCSQV
                     NQNLEKICQREGDTHHSYKHIAPVYAIAIVDSNYFQDDLAFHSFSMREDTTGEVLTIT
                     TNGQENHLVKMAFLELKKYRETSKDEVRKPWLEFFGNKPFTQEPERAISQADQLLDYK
                     SWSEEDRKMFSQLRMREEQALLAHDYSLEQAEEKGLERGRAEGLERGLERGKLFAFLD
                     MVRQGLLTSEVASQQLGMTVAEFEALL"
     gene            77595..78047
                     /locus_tag="VUR46_000073"
     CDS             77595..78047
                     /locus_tag="VUR46_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET5455584.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            78066..79403
                     /locus_tag="VUR46_000074"
     CDS             78066..79403
                     /locus_tag="VUR46_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET5455585.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            79482..80366
                     /locus_tag="VUR46_000075"
     CDS             79482..80366
                     /locus_tag="VUR46_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5455586.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            80366..81199
                     /locus_tag="VUR46_000076"
     CDS             80366..81199
                     /locus_tag="VUR46_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5455587.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            81217..83310
                     /gene="nanB"
                     /locus_tag="VUR46_000077"
     CDS             81217..83310
                     /gene="nanB"
                     /locus_tag="VUR46_000077"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET5455588.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHSNELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            83322..84425
                     /locus_tag="VUR46_000078"
     CDS             83322..84425
                     /locus_tag="VUR46_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET5455589.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNTEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHRAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            84598..85296
                     /locus_tag="VUR46_000079"
     CDS             84598..85296
                     /locus_tag="VUR46_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET5455590.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPHEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVKAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            85315..86236
                     /locus_tag="VUR46_000080"
                     /pseudo
     CDS             85315..86236
                     /locus_tag="VUR46_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            86361..87689
                     /locus_tag="VUR46_000081"
     CDS             86361..87689
                     /locus_tag="VUR46_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5455591.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            87941..88807
                     /locus_tag="VUR46_000082"
     CDS             87941..88807
                     /locus_tag="VUR46_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5455592.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSITKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            88823..89662
                     /locus_tag="VUR46_000083"
     CDS             88823..89662
                     /locus_tag="VUR46_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5455593.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            89722..90066
                     /locus_tag="VUR46_000084"
     CDS             89722..90066
                     /locus_tag="VUR46_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455594.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIINGIVNGLIGRYIKLGTY
                     AAKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLGADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            90353..90997
                     /locus_tag="VUR46_000085"
     CDS             90353..90997
                     /locus_tag="VUR46_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET5455595.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEIKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            91166..92083
                     /locus_tag="VUR46_000086"
     CDS             91166..92083
                     /locus_tag="VUR46_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET5455596.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            92101..92985
                     /locus_tag="VUR46_000087"
     CDS             92101..92985
                     /locus_tag="VUR46_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5455597.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFQEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(93001..93852)
                     /locus_tag="VUR46_000088"
     CDS             complement(93001..93852)
                     /locus_tag="VUR46_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET5455598.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            94052..96109
                     /gene="pbp2b"
                     /locus_tag="VUR46_000089"
     CDS             94052..96109
                     /gene="pbp2b"
                     /locus_tag="VUR46_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET5455599.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQIVSFTRSNKMTATDLKETA
                     KKLLTYVNISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     AYMVQTALGLMGQTYQPNMFVGTSNLESAMGKLRSTFGEYGLGSATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            96120..96716
                     /gene="recR"
                     /locus_tag="VUR46_000090"
     CDS             96120..96716
                     /gene="recR"
                     /locus_tag="VUR46_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET5455600.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            96892..97935
                     /locus_tag="VUR46_000091"
     CDS             96892..97935
                     /locus_tag="VUR46_000091"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET5455601.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSQTPGQEDRLMTNATIDWDKKVSPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFQYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKEEIFLNELNTMPGFTQWSMYPLLWDNMGISYPDLIEHLVAL
                     AKESFDKREAHLL"
     gene            98020..99393
                     /locus_tag="VUR46_000092"
     CDS             98020..99393
                     /locus_tag="VUR46_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET5455602.1"
                     /translation="MKLTIHEVAQAVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTVIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENEAK"
     gene            99380..99991
                     /locus_tag="VUR46_000093"
     CDS             99380..99991
                     /locus_tag="VUR46_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5455603.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDVEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            100082..100786
                     /locus_tag="VUR46_000094"
     CDS             100082..100786
                     /locus_tag="VUR46_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET5455604.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            101005..102378
                     /gene="ftsA"
                     /locus_tag="VUR46_000095"
     CDS             101005..102378
                     /gene="ftsA"
                     /locus_tag="VUR46_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET5455605.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            102395..103654
                     /gene="ftsZ"
                     /locus_tag="VUR46_000096"
     CDS             102395..103654
                     /gene="ftsZ"
                     /locus_tag="VUR46_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET5455606.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQVSAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            103659..104330
                     /locus_tag="VUR46_000097"
     CDS             103659..104330
                     /locus_tag="VUR46_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET5455607.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            104340..104879
                     /locus_tag="VUR46_000098"
     CDS             104340..104879
                     /locus_tag="VUR46_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET5455608.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            104879..105142
                     /locus_tag="VUR46_000099"
     CDS             104879..105142
                     /locus_tag="VUR46_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET5455609.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            105139..105924
                     /locus_tag="VUR46_000100"
     CDS             105139..105924
                     /locus_tag="VUR46_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET5455610.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPLAEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLKLLQDKGQTKKEKKKITVQLLLSK"
     gene            105933..106722
                     /locus_tag="VUR46_000101"
                     /pseudo
     CDS             105933..106722
                     /locus_tag="VUR46_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
     gene            107070..109862
                     /locus_tag="VUR46_000102"
     CDS             107070..109862
                     /locus_tag="VUR46_000102"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET5455611.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNSPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLISLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTVVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDTKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDAVAYEELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAETFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTMAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAGGFEEK"
     gene            110045..115864
                     /locus_tag="VUR46_000103"
     CDS             110045..115864
                     /locus_tag="VUR46_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HET5455612.1"
                     /translation="MRQTNVRGSLSLRGFRKLRTGAIVATGVILLGLGFSAPTASVSE
                     QDGVWVARTVAEVKADIQKEGDLFKYVIKWGDTLSVISEASNIPVDVLQEMNQASGKN
                     LFLPYNELYFTEAETVSDTVTKHKIVIKESGASGEVRTYEVLLKKDQETKAVTFELTD
                     VTEKVEKMTVNYSPVYQPVSVPVVERAEESVEEPALVAPAVTSPEVKEETEDPVVLKA
                     EEAATTPATKETAPEVVTPAEPNAETPAPKVEAPTESSEPKGTEPEVAKPAGDSVSST
                     SESNEDGNSGDSTHSTLTSDETKPEEVESTSVTDNVPSNAGTTNQPLTPTSNSDDSAP
                     KEVANGTEGKVEAPKVEEAVSEGEEGNAEITNNPSTGATPSSDETTEQSGTPAPKPEE
                     EAPVATETSAASAESTESAPVVAKPAEPKAETPEATITGDEGKESEESGTSATVESTP
                     AGEEGKAEDSVSSTESSSTASEGESTATQPAVEAGTDSTSEAEELATTETATTPKTEE
                     PEAVAPAPEAPSESDSKEEDSAAGDTTVTEEQPAAETVSEGGSPATQPAGEEGKSEKE
                     PKVEGQPSGTESATPEQHTNIEETTEKQSGATSENSGDSLVSDEPAASSGISTSSGTE
                     GAETIDTETIAEKSEIPSPAEEGSAKEEKEVIKKLELRNISSVELYSKEGDKYRHVTS
                     LATLPSNPETYFMKVKSENFKDVMLPVTSITNDNKDNRDVYKIVASVKNLIQHENNKV
                     LENYTYYLSKTQQGETGVYTSFKNLVDAMNRDSYGEFRLGATMDAREVELPDGQESYV
                     KNVFHGRLIGQNSNKYYAIYNLKKPLFNALSNARVQNLSLKDVNISAKDDTATLAKEA
                     NNNTHIDNVHSDGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLV
                     GKLSGPNGLIDKSIASIDLASNATRGDQSIGGIAGSVIDNAVISSSYAEGKLNNVQPF
                     ANVGGVVGDLWDPVGGLEKSGQLSNVLSDVNVTNGNAIAGKHFDHMKATNVYSNKNNK
                     VVNVVQENDEILTKDSVVQRGEVLEDEQIKEKKAAFVTKNTVKTEDFNFSSRYVTDYK
                     NLENADSSKEKVYKNIEKLLPFYNSETIVKYGNLVETSSNLYNKELLSVVPMKDKEVI
                     SDINKNKSSINKLLLYYADNSYETLNVNYQSDFSNVAEYSIGGTNLIYTPNTLLRDYN
                     NILDGVLPVLETVDYKSDAIRKVLDVSNDVSLTELYLEEQFNTTKNNLRDSLTKLLTA
                     DAAISENSNSIIDNYVIEKIKNNKEALLLGLTYLERWYNFKYGETKAKDLVMYHLDFF
                     GKSNSSALDNVIELGKSGFNNLLAKNNVITYNVLLSKNYKTNNLFDALEKYRKVFVPD
                     KTNNEWFKEQTKAYIVEEKSTIKEVNDKQSKAGTPQSIGVYDRLTSPSWKYPSMVLPL
                     LTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTNLNDYVEAKAREAAVRFRDHYDYW
                     YKILDNNNKEKLYRSVLVYDAFRFGADDKGERETKQANFETDHPAIKHFFGPAGNNVV
                     HNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYA
                     KGLLQAPDHPDDPTITINSILKYEESEDPTRLQVKDPTKRFNNAEDLQKYMYNMFDVI
                     YMLEYLEGNAVVKLDISKKNELLRKIENKFETDPDGSNVYATNVVRYLKPEELTKLTS
                     FNSLIENDVITRRGYENGNDNTFKRNGYYTIKLFSPIYSALSNNEGTPGDLMGRRMAF
                     ELLAAKGFKDGMVPYISNQYAEEAKAKGKVIKSYGKEVGNVTDELVLQKIFNNRYSSW
                     VEFKKAMYNERIAKFKKLMSISFDNPNGNWFRKDRVTIKNIEDLQRMITTAVNEDAED
                     YLVNIYPERSRVLKLKKAIFKAYLDQTNDFRSSIFDEEK"
     gene            116023..116715
                     /locus_tag="VUR46_000104"
     CDS             116023..116715
                     /locus_tag="VUR46_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET5455613.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(116765..>117219)
                     /locus_tag="VUR46_000105"
     CDS             complement(116765..>117219)
                     /locus_tag="VUR46_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5455614.1"
                     /translation="RKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLL
                     FHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNN
                     LIKLIKRNAFGFRNFENFKKRISIALNIKKERTKFVLSRAYLTSTHYS"
BASE COUNT        36186 a        21152 c        26052 g        33829 t
ORIGIN      
        1 gaaacagcta gtgtgttgga agtttgaaca aggcttgggt aacagacttt ttaatgaagt
       61 ccaagcaaca aggagaaaaa gaaacaacca tgagtccatt ccatgactct attgttctag
      121 aaaaccttgc aatagtcaaa tgataacgaa taaaacttgg gattgaaata tccccatgat
      181 tatatattac gaggagaaag aaaatgaaaa aatttgttgc tgagttaatc ggtacgttca
      241 tgcttgtatt cgtcgggaca ggagctgttg tttttggaaa tggtcttgat ggccttggtc
      301 accttggaat cgcctttgct tttggtttag caatcgtggt ggcagcctac tcaatcggaa
      361 ctgtttcagg tgctcacttg aacccggctg tttcgattgc tatgtttgta aacaaacgtt
      421 tgtcatcttc agaacttgta aactacatcc ttggtcaggt tgttggagct ttcatcgctt
      481 ctggcgcagt cttcttcctc ttggctaatt caggtatgtc aactgctagc cttggtgaaa
      541 atgccttggc aaacggtgtc actgtctttg gtggtttctt gtttgaagtc atcgcaactt
      601 tcttatttgt cttggttatc atgactgtga cttcagaaag taagggcaat ggcgcgattg
      661 ctggtttggt aatcggtttg tcattgatgg cgatgattct tgtcggattg aagattactg
      721 gactttcagt aaacccagct cgtagcttgg caccagctgt cttggtgggc ggcgcagccc
      781 ttcaacaagt ttggattttc atccttgcac caatcgctgg tggagttctt gcagcccttg
      841 ttgcaaaaaa tttccttgga acagaagaat aattgaaact caaaaagcct tgctcctcat
      901 cttgaggaac agggcttttt cgtatgatac tcttcgaaaa tctcttcaaa ccacgtcagc
      961 ttaaccttgc cgtatgtata tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca
     1021 gtgttttaag ctgacttcgt cagtcttatc tataacctca aacactgctt tgagcagcct
     1081 gtagctagct tcctagtttg ctttttgatt ttcattgagt atgagtttaa cggttgtcaa
     1141 ttttctctgg ataaagatcg tgttggaaga ggcgttgttc tgccaagccg tcatacttgg
     1201 ttccaggtct accgtagttg tagtaggggt cgattgaaat gccaccgcgc ggagtgaatt
     1261 ttccccagac ttctaaatag cgagggtcta gcaagttgac caagtctttc ccgatggtgt
     1321 tgatacagtt ttcgtggaaa tctccgtggt ttcggtagct aaatagatag atatattgag
     1381 ggattttgac tcgacacaga gcttatcagg aatgtaggaa atatgaatcg tcgtaaagtc
     1441 tggctgagca gtgatttgtc ccagtagaga catatcgagg atatggtgac gaatgccctg
     1501 ttccttagcg atttctctag caatttgaat ttcgaggtga tgacgttggc cgtaggcaaa
     1561 ggtgacagct tcgattgttt catagtgttg catggcccag aaaaggcagg ttgttgaatc
     1621 ttgaccgcca ctaaagacga ccaaggttga ttgacgtttc atagtactcc ttccaaaatg
     1681 ggaaatgttc agagaacgca aaaagctccc attagggagc taaaaaatac caaatcgagt
     1741 ttttttagcg atggcatatc ccaaacatcg taatattcta tttatatagt aaaatgaaat
     1801 aagaacagga caaaacgatt aggacagtca aatcgatttc taacaatgtt ttagaagtag
     1861 aggtgtacta ttctagtttc aatctactat agtctagcat attttttgaa aaatggcaaa
     1921 gggcaagaaa aaagagacca aagaaagtac ttggtctctc gtttgattag ctcaattcag
     1981 caacgatggc cttgatttgg tctgctgtgt gaacaccagc aacttgtttc actacttggc
     2041 cgtctttttt gaagagaaga gttgggatag acatgattcc aaaagcacga gctgtgtttg
     2101 gattttcatc cacgtccatt ttaacgattt tcaagacatc ttctgaaagt tcttcagaca
     2161 atttgtccaa gattggacct tgcatacgac atggaccaca ccaagttgcc cagaagtcta
     2221 ctaagaccaa accgtctttt gtttcttgtt cgaatgttgc atctgtaatt gcctttgcca
     2281 ttgtatttct ccttttttag ttatattggc ttaaatcttg tttcatgaga tagaagaaga
     2341 catctccata agtcccatga tagtccaaat cataaccctt gtaagttaat ttttggacag
     2401 ggtagtagtc tgcgacgccg ataaggcaag cttgttgcga acgatcaaag tcttcataag
     2461 aatcgaaggt tacagttctt tcgttcttgc tggcatctag ataggtaatt tcaatcattt
     2521 aaaaactcct tttttaatga tgactttatt ttactccttg taaaagagaa tgtcaagaaa
     2581 aatgcttgcg cacgcaacat tcttccgaaa tcatcttaaa tcaagaaatc caaaccagtt
     2641 tccaagcttg tttcgacagc tttctgtaga gaggccagtg tcttttgccc atcacttgtc
     2701 aggcagataa agctagagcg tctatcttga tggcaacaca tgcgactaag cagaccgcaa
     2761 tttttagctt ccaatcgagc caccatccga gaaacagcgc tcgggctcag atgaagctta
     2821 tctggcagat caatctggcg tagagatttt tcttcagcca agtccagata gtagagcagg
     2881 tagaactctt tcaaggtcag actttgttca ctctgctggg caatggtgtc ttctaacaag
     2941 gtttcgatct ctttctgacg ccgattgaag tcaaaccatt tttccaaata ggtcatagta
     3001 tctcctttct ttttagagtt gtaaatagaa gaaagtccat tcacggacag tctttgcgtc
     3061 acaagatgat tgcgcatgca ataattatac tacttttcaa aagagctagc aagctctgtt
     3121 ttttagtggt tttatttttt actgtccata tttttgataa aagtcaactt ttacttggat
     3181 gaaggttttg gcttcacgta ggagttgaag aagggtggcg cgggtttcaa attcgtctct
     3241 tgtcttgggc agactgcggt ttcgaaagac ttccagatag cgttcaattt catctagcaa
     3301 atcagaagca ggattggtct gactcagttg accggcaatt tttgaaaaga gttgtgctaa
     3361 aatcaggctc tcactgacag ctaggtgaca ggtattgatt tgctgggcca tatttcgcag
     3421 gatacgcctt tgtcgctgtc tcatctcaaa gtagtggata tggtagtcgg tttggtgaaa
     3481 gaggtggtca gagtgatcta aatagaccag tttgagggct tcttccacca gcgtgtggta
     3541 gtgctggatt tcctcttctc gtgaaggcat gtagagattg accagtaaag caaatcctgt
     3601 accgatagca aagagaaaga attcattgac tagaaggtct ggagaggttg actcttgtac
     3661 caagaggtgg ctaaccaaaa cagtacttgg tgtgatgcca atttcccagc ccatcttgta
     3721 ggctagaggc acatagaagg caagatagag accaaggctc cagatatgaa atccgctcaa
     3781 gtgaaaagct agaacaccga tagccagagc taggagcatg gaaaagagtc gattgcgagc
     3841 cagttttaag gtacttctac gcgtatcaga taggctcaag agagcgataa ttccagccga
     3901 aactgctgag gaaagattga gaaaataagc aagaaaacag gcaagacagg tagctaagat
     3961 gagcttggtc gtacgttggc taatagacat aagaatttcc tgataagtta gaataaaagc
     4021 gtaaaagaca agacctgagc aggcttgcct ttatgagtta ttttttacgg gctgctgcgt
     4081 attcggcaac ggcggtaaag aggacatctg tagaagagtt aagggctgtt tcacatgagt
     4141 cttggatgac accaatcaca aaaccacccc caacaacttg tatggcaata tcgttagaaa
     4201 taccgaaaag gctacaagca actgggataa ggaggaggga acctccagca ataccagaag
     4261 caccacaggc tgagatagct gctaccacac tgaggacaaa ggctgtggca aagtcaacag
     4321 gaattccaag agtgttaact gcagcaaggg tcaaaacgtt aatggtaatc gctgccccgg
     4381 ccatgttgat agtagaaccg agtgggatag aaacagaata ggtatctggg ttgagtccaa
     4441 ggtcatggca gagtttcatg ttgacaggaa tgttagccgc agaactacga gtgaagaagg
     4501 ctgtcacacc gctgacacgg aggcagttcc aaactagagg gtaaggattg cgtctcataa
     4561 agaagaaggc aatcaagggg ttgaccacaa gggcaacaaa aagcatagtc gttactaata
     4621 gaaccaataa aataccgtag ttggcagggc ttccgattcc cttgtcagaa atggttttaa
     4681 aaacaagacc aaggattcca aatggagcca gattgatgat ccattcgaca attttagaag
     4741 tcacgtcagc gatagttttt agtaattctt tactattttt gctggcctct ctcatggcaa
     4801 tcccgaaaac aactgcccaa gataggatac cgatgtagtt ggcagtaatg agggcattga
     4861 ctggattgtc aaccagtttg agcaagaggt tgctgaggac ttgtccaatc ccatctggtg
     4921 gagcaatttc ggtattggca ctatttaggg tgatttcaat agggacgatg aaactagcta
     4981 caacagctac aagagcagcg gcaaaagtcc ctaggatata caagagaaca accgttttca
     5041 tattgctatc ttgtcccttt tgatgttggg aaagggcatt ggcaacgagg gcaaagacta
     5101 ggataggagc aacagctttt agacctccga cgaataaatc cccgagtagc ccaatccctg
     5161 agagattagg aagggtcagt cctaggattc ccccacaaag cataccaatc aagatacgct
     5221 tgacaaggct tgccttattc caagcatgaa tgattctttt cataataatc tcctttttgt
     5281 gtagtggtta tgattatagt ataaatgata gacaaaatca agaattttct gtctattttt
     5341 tgaatattta tggagaatga gactgatgaa aatatggtat aatgaaataa aggagtttta
     5401 tatgcaaaaa tttattcagg cttatattga aaagctagat gtgacaacca ttatcgagaa
     5461 tattctaacc aaggtcattt ctcttttact gcttttgatt gtattttata tcgctaaaaa
     5521 aatgcttcat accatggtgc agagaattgt caacccctct ctaaaaatgt ctcgtcatga
     5581 tgtcggacgc caaaaaacca tctcacgttt actagaaaat gtgtttaatt atacgctata
     5641 tttcttttta ctctactgca ttttgtcgat tttaggtttg ccagtttcta gtttgctggc
     5701 tggagctggt attgctgggg tagcgattgg tatgggagcc caaggctttc tgtctgatgt
     5761 tatcaatggc tttttcatcc tctttgaacg tcaactggat gtgggagatg aggtcgttct
     5821 gacaaatgga ccgattactg tatcgggtaa ggttgtcagt gtgggaattc gtacgacaca
     5881 gcttcgtagc gaggagcaag cccttcactt tgtccctaac cgaaatatca cagttgttag
     5941 caatttctca cgcacagact agacctgtta ttttaagtaa tttgtggtac aatagaggga
     6001 gtttaataag gagaaaagat ggttttagaa aagcagttgg gcaatggttg tacctggata
     6061 gacctagatc taggaaagtt gaataaacta gaagaccttt ctgaaattta cggtttggac
     6121 aaggaaacca ttgaatacgc actggataga aacgagcgcg cccacatgga ctaccaccgt
     6181 gaaagtggga cggttacctt tatctataat gtcctagacg taaaaaagga caaggcctac
     6241 tatgagactt ttcccatgac ctttatcgtg gagcatcgtc gcctgattac cattagcaat
     6301 accaagaacg cctatgtcat tgaacagatg actcgttatc tggagagcca tgacacgctt
     6361 tcgatttata agtttctctt tgccagtctg gaaatcatca gcaatgccta ctatcctgtc
     6421 attgagcaga tggacaagag tagggatgag gtcaatgacc tcttgcgcca gcgaactacc
     6481 aagaaaaacc tctttgccct gtctgatttg gagactggta tggtttatct gacggcagct
     6541 gccaaacaaa atcggatttt gttagagcat attcaaggtc atgccttgta tcgtagtttt
     6601 gatgagattg agagagaaca gtttgatgat gccatgattg aggctcatca gctggtatcc
     6661 atgacagacc taatctctca gattttacag cagctttcag cctcttacaa caatattcta
     6721 aacaataatc tgaatgacaa tttgacaacc ttgactatca tttcagtctt gctagctgtt
     6781 ttggcagtcg tgacaggctt tttcggaatg aatgttccct tacctttaac agatgagccc
     6841 catgcttggc tctatatcag tttggctagt gcaggtttat ggattgtttt atccttgtta
     6901 ctaaggaaaa ttgcgaaaaa aagttaagaa aaggagccag aatggcgatt gaaaattata
     6961 tgccagattt tgctgtggaa gcagtctatg atctgacagt cccaagcctg caggcgcagg
     7021 gaatcaaggc tgttttggtc gatttggata ataccctcat tgcttggaac aaccctgatg
     7081 gaacgccaga gatgaagcaa tggctacatg accttcggga cgcgggcatt cgcattatcg
     7141 tggtgtcaaa taacaccaaa aaacgcgttc aacgagcagt tgagaaattt gggattgatt
     7201 acgtttactg ggccttgaag cccttcacat ttggtattga ccgtgccatg aaggaattcc
     7261 actatgacaa aaaggaagtg gtcatggttg gcgaccagct catgacagat atacgagcag
     7321 cccaccgtgc agggattcgg tcaattttag tcaaaccctt ggtccaacat gactcaatca
     7381 aaacgcagat taaccgaact cgtgagcgtc gtgttatgag aaaaattact gaaaagtacg
     7441 gaccgattac atataaaaaa ggaatctaac tatggaagaa attctctgta ttggttgtgg
     7501 agcaaccatt cagacgacag ataaagctgg tcttggtttt accccccagt cggcacttga
     7561 aaaaggtttg gagactggcg aagtctattg ccaacgctgt ttccgtctcc gccactacaa
     7621 tgaaatcaca gatgtccagt tgacgaacga tgatttcctc aagctcttgc acgaggtggg
     7681 agacagtgat gccttagttg tcaatgtcat tgatatcttt gattttaatg gatctgtcat
     7741 cccaggttta ccacgtttca tctcgggcaa tgatgtcctc ttggtaggaa ataaaaaaga
     7801 tatcctccct aagtcagtta agtctggtaa gattagccag tggatcatga aacgtgccca
     7861 tgaagaaggg cttcgtccag tcgatgtggt cctaacttca gcacaaaata aacatgccat
     7921 taaggaagtc attgacaaga ttgaacacta ccgtaagggc cgcgatgtct atgtggtcgg
     7981 tgtgaccaac gttggaaaat caactctaat caatgctatt atccaagaaa tcacgggtga
     8041 tcagaatgtc atcactactt cacgcttccc aaggacaacc ttggacaaaa tagagattcc
     8101 gcttgacgac ggatcttata tttacgatac gccgggaatt atccaccgcc accagatggc
     8161 tcactacttg acggccaaaa acctcaagta tgtcagtcct aaaaaggaaa tcaagccaaa
     8221 gacctatcag cttaatcctg agcaaaccct atttttaggt ggtttgggac gctttgactt
     8281 tatagcagga gaaaagcaag gatttactgc tttctttgat aatgaactca aactccaccg
     8341 tagcaagctt gaaggagcta gtactttcta cgataagcac ctgggaactc ttctgacacc
     8401 accaaatagc aaggaaaaag aagatttccc aaggttagtc cagcgtgtct ttaccattaa
     8461 agataagaca gacctagtca tctcaggcct aggttggatt cgtgtaacag gcatagcaaa
     8521 agtcgccgtc tgggcaccag aaggcgtcgc cgtcgtcata cgaaaagcaa ttatttaaaa
     8581 caaaatcgct gagcgaacaa agtgagctca tatagcgata gttattgccg tggtgtgatt
     8641 gccaatctgt agattggcaa ggggcacaat tgagaccaag gctcaattgt gaggtcagga
     8701 aatccatttt tcaaagatga aatctttgga aaattagttc cgaccgtccc tcaccaccta
     8761 aaataactat caaaaaacaa ggaagaaaat tatgtcatta acatcaaaac aacgtgcctt
     8821 cctcaacagc caggcacaca tcctcaaacc tatcatccaa atcgggaaaa atggactgaa
     8881 cgaccaaatc aaaaccagcg tccgtcaagc tcttgatgcg cgtgaattaa tcaaggttac
     8941 tctcttacaa aacacagatg aaaacatcca cgaagtagct gaaattttgg aagaagaaat
     9001 cggtgtggat acagtccaaa aaataggacg catcttgatt ttgtttaaac aatctagcaa
     9061 gaaagaaaat cgcaagattt ctaagaaagt caaagaaatc taagaccgaa actccaaata
     9121 actgttttta cagagaaata aaggagacta gcctatggca atcgaattat tgactccctt
     9181 taccaaggta gagttggagc cagaaatcaa ggagaaaaaa cgcaaacaaa tcgggatttt
     9241 aggggggaat tttaaccctg ttcacaatgc ccatctcatt gttgcggatc aagtacggca
     9301 gcagttggga ctggaccaag ttctacttat gcctgaatac caacctcctc acgtagataa
     9361 aaaggaaacc atccctgaac accatcgtct caagatgctt gagttggcga ttgaggggat
     9421 tgaaggctta gccattgaaa ccattgagtt ggagcgcaag ggcatttcct acacctacga
     9481 caccatgaaa atcttgacag agcaacatcc agatacggat tattacttta tcatcggtgc
     9541 cgacatggtg gactatctgc ctaagtggta ccgaattgat gagctggttg acatggttca
     9601 gtttgtaggg gttcagcgcc cgcgctataa ggctggaact tcctatccag ttatctgggt
     9661 ggatgtgcct ctcatggaca tctcatccag catggtgcgt gacttcattg ctcaagggcg
     9721 gaaacccaac tttctcctac ctcagcctgt actggactac atagagaagg aggggctcta
     9781 ctgatggcat atcaagacta tatcaactgc tcccgtgagg ctttgttgga aaaaatggca
     9841 gagcttctac ctgaaaaacg tttaacccac tgcttgggtg tggagcttgc agccatagaa
     9901 ctagcagaga gatttggagt agatgttgag aaagcaggtc tagcaggcct tcttcatgac
     9961 tatgctaaaa agctgtcaga tcaggaattt ttagacttga ttgaccgtta tcagttagac
    10021 cccgacctca aaaactgggg caataatgtc tggcatggta tggtcggaat ttacaagatt
    10081 caggaagatt tgaatttgca tgattctgaa attctacgag ccattgaaat ccatacagtc
    10141 ggtgctggtc agatgaccga cctagacaaa gttatctacg tcgcagacta tatcgagcac
    10201 aatcgagcct ttcctggagt ggacgtggcg cgtgagattg cgagtctatc gcttaataag
    10261 gcggtggcct acgaaacagt tcataccgtg gagcatctag ctcatcaggg atttcccatt
    10321 tatccccaaa cccttgaaac ctataacgcc tttgtgcact atttgaaaga ggactaaatg
    10381 aacgaaaaag aattactaga actagtcgtg aaagcggctg atgagaaacg tgcagaggat
    10441 atcctcgcac ttgatgtaca agatttgacc agcgtgacag actactttgt tatcactagt
    10501 tcaatgaata gccgtcagtt ggatgctatc gctgacaata tccgtgaaaa agtagctcaa
    10561 gcaggcttta aaggtagcca tatcgaaggt gatgcaactg gaggctgggt cttgctggac
    10621 cttggtgctg ttgtcgtgca tatcttctca gaagaaatgc gtgcccacta taacctagaa
    10681 aaactatggc atgaggcgca ttctgtagat ttatctgaaa ctttatagtc ttttccttta
    10741 tcttttatta cggcgttaac tcgttttgcc taactccagt tatgcctgca actcgttgcc
    10801 tagtactaaa agcaaacgaa aagactatag tgtacaattg aactcagttg tagtcaactg
    10861 ggttttattt gcttatttta gaagaaaatg gatagaaagg taaagggcga atggtgttta
    10921 ccatggaggc tcttggtatc atgattatgg caacttatga aacttttgcg gcggtctatg
    10981 atgaggtcat ggatgacagt ttatacgaca aatggactga tttttctctg cgtcatttgc
    11041 caaaaactaa ggagagaaag aaactcttgg aattggcttg tgggacagga attcaatcag
    11101 tgcgcttctc tcaggctggt tttgatgtga ctggactgga cttgagcgca gatatgttga
    11161 aaattgccga aaagagagcg gcttcagcca agcaaaagat tgattttatg gaaggtaata
    11221 tgctggattt gtccaaggca ggtcaatacg actttgtcac gtgttactcg gactcaatct
    11281 gctacatgca ggatgaggtg gaagtagggg acgtttttca agaagtctat aatgtcctca
    11341 acgaagacgg agttttcatc tttgatgtgc attcgactta ccagacggat gaaatttttc
    11401 caggctattc ctaccatgaa aatgcggaag attttgccat gctctgggat acttatgagg
    11461 atgcagcacc tcactccatc gtccatgagc taactttctt tatcaaggag gcggacggtt
    11521 cctttagtcg ccacgatgaa gtgcatgagg agcggactta tgaggttctg acctatgata
    11581 ttttgctgga acaggccggt ttcaagtcct tcaaactata tgcggatttt gaggacaagg
    11641 agccgacaga gacaagtgcc cgttggtttt ttgtcgcgca gaagtaggag attagcatga
    11701 ccatcacggg tattattgcg gagtttaatc cttttcataa tggacacaaa tacctgctgg
    11761 aacaggctga aggactgaaa gtcgtggcta tgtctggaaa tttcatgcag cgtggagaac
    11821 cagcgattat agataagtgg atacgggccc agatggcgct ggaaaatgga gcagatctgg
    11881 tagtagaatt gcccttttta gtcagtgttc aggcagcaga tttcttcggt caaggagctg
    11941 tggatatctt ggctcggttg ggcattgata ctctagcatt tgggacggag gaagttctgg
    12001 attatcaaaa aatcgctgac ttatacacag agcaggaggc tgagatggag aaatttgtgg
    12061 aaaaactgcc tgattctctt tcctatcccc agaaaaccca agccatgtgg aaagaatttg
    12121 cagatcttga tttttcaggc aatacaccca atcatgtcct tgctcttgct tatgccaagg
    12181 cggttgctgg acgaaatatc aagctccatc cgattcagcg tcagggggct ggttaccatt
    12241 ctgtggacaa ggatgtggac tttgcctcgg cgacggccct ccgtcagcac cagtcagatc
    12301 aagatttctt agaacgcttt atgccatctg ttgccctctt tgagcaggcc agtaaggtga
    12361 gctgggatga ctattttcct atgctccgct atcaaatctt gtccaattca gacctaacca
    12421 ccatctatca ggttaatcaa gaaatggctg tgcgcattaa agaggctatt aaaccagccc
    12481 agtctgtgga agacttggtt aaggtggttg cgaccaagcg ttacaccaag gcgcgtgtca
    12541 gacgtctttt gacctatatt ttggtgcaag ttagagaaag tgacttgtca gaagccattc
    12601 atgtccttgg atttactgaa aaaggcaggc aacatctcaa gtctttgaaa ggtcaggtca
    12661 atctagtcag tcgaattggc aaagagcctt gggatactat gacccaaaag gcagaccaga
    12721 tttaccaact aggaaatcca agtatagcag aacagaattt tggaagagtg ccaataagaa
    12781 tagaaacaaa ctaagtctac tgaaaggtag gctttttgag attttttacg aataaataga
    12841 tagaaaagaa aatcttgtac aagtttctga caatttcttt cttttcgtgt ataatagtgg
    12901 aaaagaggta aaacgaggta tggttatgga agcagttctt tactcaacat tccgaaatca
    12961 tttaaaagac tacatgaaga aggtcaatga tgaatttgag cctttaacgg tggttaataa
    13021 aaatccagat gaggacattg tagttctttc aaagagcgaa tgggacagta ttcaggaaac
    13081 cctgagaatc gttcaaaata aggagttatc agacaaggtt ttgcgaggaa tggctcaagt
    13141 ccgtgctgga agcactcaag tccatgttat tgaggagtga ggaatgctgc tcaagtttac
    13201 agaagatgcg tgggcagatt attgctactg gcaaactcag gataagaaaa cactaaaaag
    13261 aatcaataaa ctaattaagg atattcaaag tgattcattt acaggaatag gaaaaccaga
    13321 accactcaag tatgactacc aaggagcctg gtcacggcgt attgatgcag aaaatcgctt
    13381 gatttatatg atggatggag atagcatcgc ttttttgtcc ttcaaagatc actactaagt
    13441 ctactgaaag gtgggctttt tattttttaa atttttatga gtaagtttaa gataaagttt
    13501 tttagaaaat gacagaatcc ctaatacaaa agacaaaaac tcagtaaaga aatttagtat
    13561 ataaacttcg attttttccc ttgaatccgc tttatcactt gtattttgtg gtataatgaa
    13621 gagaattgtt aataataaaa acaggggaag taaatgtcta gtttcaaaga aaaattacca
    13681 ctattccaag caaatgatat ccaaatctct aatgatgtca atacggtttg gtctatcgct
    13741 aacactctta gaggagctta tcgagcagat aagtatcgcg atgtcattat tccaatgttt
    13801 gtcctgactc gtttagaagc tgccttactg ccaaccaagg atcaggtggt agcacaatac
    13861 aaagcaaatc ccaatacacc tgagaaagtg ttggagaaac tttcaggcta tcgttactac
    13921 aatgttagtc cttttacgtt ggaaaatctt caaaacgatc caaatgcaat cgaggagaat
    13981 tttatagcct atctggatgg ctattcttgt cgtgtcaagg acatcattga aaacctaaaa
    14041 tttaaagagc aagtccgtac cctggcccag agtggtcgcc ttttcacggt tattaaaaag
    14101 ttctctcaaa ttgatttgtc tccaagttca gtcgactcta tgcgtatggg atacatgttt
    14161 gaggatatca tccgccgatt ttctgaaaat gaggaagcgg ggtctcacta tacccctcgt
    14221 gaggttatcg ctctgatggt caacctcctc ttgattgagg cagacgaaga actttttgtt
    14281 gataaaaaag agttgaaaat actagacatg gcggctggaa ctgggggaat gctggctaca
    14341 gctaaaagct atatccgtca gttgaataca ggagccactg cccgactctt tggtcaggaa
    14401 gttttgcctg aaacctttgg gattggtcgt gcagatatgc taattcgtca ggaagactct
    14461 gactattttg tgaaggtgga taccttaaaa gatccagatc cttttccaga tactaaaatg
    14521 agctttgtca tcgctaaccc tcccttcggc caagcttggg gtggtaagga tgcggatgat
    14581 ggagttgagg atgcagttaa gaaagatcat caactctttg acaaaacaga aggtcgtcaa
    14641 ggtcgttttg ttgcgactcc aggaactgga gatgctcaac tactcttcca tcttcatgct
    14701 cttacaaaat tagaagaaaa tggccgtgca gccatcattt caaatgggtc tcccctcttt
    14761 tcaggtggga cgtcatcggg agaaagtcag attcgccgtt atatcctaga gaatgacttg
    14821 ctagaagcta tagtcgccct tccaggtcaa tttttctata acacaggaat tgggatttat
    14881 atctggattt ataataaaaa caagtctcct gagcgccaga acaaggttca gtttatcgat
    14941 gctacggagg agtttattcc tctacgtaaa tctctaggtc aaaaacgccg tgagttgtcc
    15001 caagataaca tccgtcagat ccttcgctgg tacgatgatt ttcaagaaaa tgaccatgta
    15061 aaaatctttg agaatcaaga gtttctctat cgagagttta cagttatgca acctctgcaa
    15121 cgtcgtggcc agataagtga agaaacaatt gagaaagcga aaagtgttcc tttcctagct
    15181 aaactatttg atgaatacaa gtaccaagaa ttgctggaga tggaaccacg ttcagccaag
    15241 gatgagaaaa aattacagga ctttgtagct ggcaagatca agcaagaagc tatcctgaca
    15301 gctcttgcta agggaagttc tgacaagacc tatcctgact ttgagaactt tgtccaagtc
    15361 atcaaggact tgctgggaga gtttaagctt acgcctgcta atatcaatgc gctagcctta
    15421 gctatgagtg aaatggataa gacagcagag gttatccgaa ccaagaagaa agacaaggca
    15481 aatgagattg ccgatggaat tgtctacgat aagacaacca aggacagtga aatcgttaag
    15541 ctgacagagg atgtggaaac ctactttgcg cgtgaggtct atccccatgt acctgacgcc
    15601 cactactggt ttgatgagga aaaaggctat ggagcagaaa ttccttttac ccgctatttc
    15661 tatcaatatc aagaaccaga aagtgcagaa aagctcttag ctgagttcta tgccttggaa
    15721 gcagaactac agactctctt ggaggaactc aaacatgact aggatgaaag agagtggcat
    15781 agactggatt ggacagatac cagaagagtg ggtgatttct aaaataaaat tcacaacaca
    15841 gcttaatggt agaattggtt ggcaaggatt aacatcagct gaatataaag aggaaggccc
    15901 atatttaatt acaggaactg acttttacaa tggagcgatt aattttgaaa cagctgtaca
    15961 tattgatgaa aaacgttggt cagaagcttc acagattcag gttgaaaatg gcgatttgct
    16021 aattacgaaa gatggtacgg tgggtaaagt agctattatt tcagggcttg atgataaggc
    16081 ttcgttaaat agtggtgtat taagaatcca aactgttgat gagattgata gaaaattttt
    16141 atatttggtt ttgctatcag atgaattttg gatgtggttt aactatacaa attcaggagc
    16201 tagcactatt ttacatttat atcaaaatgt atttgatgaa tttactttta cctttccctc
    16261 aaaaaatgaa caacaaaaga tcgctgattt cctagacaag aaaacagctc agttagataa
    16321 ggttaaagcc ctattggaag agcagattca aaaactcaaa gactaccgcg ctagcttgat
    16381 ttatgaaaca gtcacaaaag gactggataa aaacgtccct atgaaggatt caggaatcga
    16441 ctggattgga caggtgcctg aaggatggga gatttctaaa ataagatatt tagtaactac
    16501 tcgaagtgaa aaaagaataa cagactcttc tataccttac ataggattag aaaatataga
    16561 aagtcaaact gggaaatttg ttgaaactgg tatacaagtt gataagagtg agaatattgt
    16621 agtcgaaatt ggagatgttt tatttggaaa gctgagacca tatttgagaa aatattggcg
    16681 agctaccttc ccttcaacag ctagttcaga atttcttgtg tttcaatctt cagaattaga
    16741 catgaatttt ctctactatg ctattcaaag tgatagtttt attgaagaag ttaatacttc
    16801 tacttatggt agtaaaatgc ctagagcaag ttgggaatat ataaaaaata tgaaaattac
    16861 ttttccatca agccttgttg agcaacaaaa aattgctaat cttttggatg aaaacaccgc
    16921 tcaaattgat aaccttatac aaatcaagaa tcagcaaatt aaaaatatta acaaacaacg
    16981 acaaactctt atttatgatt atgtgacagg gaagaggagg gtgtaggatt gctatttgga
    17041 actgatttaa aatttcgttt agcttacttt tttaccgcat tttttccagc atttttattg
    17101 atttattttt cattagtaga tattcatcat tttttattaa aagagactga gtcgttacct
    17161 tgttatttaa gtaggaactt gtggcatttt cttatgttat cagtattact ttctataatg
    17221 ctaatatcaa tttacagtat acgtggatat ataaacggac ggaggagtga agaaaatatt
    17281 gttaaaaata ttgttttaaa ttttaatgta tttaaggtca cgttgaaaaa taattctcaa
    17341 ggcaaagtga ttgatattca agacggacca aaaataaatc caggattcat atcctttgta
    17401 tcgtcaacca ttgtaccctc tttagttttg aaatttatga atggagttag tgctctagta
    17461 gcaattataa ttattgtttt cttttttgtg ttattaatgc ttagcaatga tatttttcca
    17521 aacttgatat tacctatttt tggtgtcaat ttactagtca caaaagataa ctacaatata
    17581 tttttctttc gaaaagactc ggctgcattt tctggtgtga aaaggatttg tactctagga
    17641 aatactggta caatggcaag aacatttgtt ttttttgatc aagaagtatt aaatgatgaa
    17701 ataggagagt agaatggtag aaatatatgc aattggttgg caggttggac gaggtaagtc
    17761 acttgggaaa ttgaaaaatt ttcgaaaagt tatctcagat gaagctagta attatatagg
    17821 taatattcaa tttgctaata atcaaaattc taatgaatca actttaactt taaaggaaaa
    17881 atttgaagaa tcaattgagt cattacaaaa tgttgaaacg aatgggaata atacggaagt
    17941 tccattttat agaaagattg atgagagtct ccagtctgaa atagatagaa tacaattagt
    18001 ctcatctcaa ttagaaacag atttacctcc tctaaagaac tttgaagata tacgattgta
    18061 tctagtttgt gaagaaattg atggtgtaca gtacaaatat tttttgaaat caattcgagt
    18121 tgcgaaatta aaaactagat tcattgctac tttgacttct ggaaaagtta aaatagttga
    18181 tatagaaaaa gatgagggaa gaagtcttcc gtttatcata agttatgctg aaaaaactga
    18241 aaacaatgaa actatacaat atatctttga tgttcaggat tatgaaatta tgtttggttt
    18301 aaatgagtcg aaaataatca cggctgaaga gaattataag aaatttttat ctcataattt
    18361 taaattatcg acggatttta aagtgaaagt atctgatgaa gaatctgaaa aaataaaagc
    18421 taaattaaaa agtcatcgta aattgattaa tttgcttgca aaatataatg atgaagcatc
    18481 gagctatgaa tggaaatgtg taaagagagc gaataaatta tcagcacagt tttttcaaac
    18541 accttttact tttaatgaaa aaagtaaaga gatatatcta acagcagagt ctcttgaggc
    18601 ctttatttct gtgattacaa atgcaaagaa attgggtatt gctaaaaatg aatacgaaga
    18661 ttcacttgca gataaacgtc agaaagataa aaaagataat attgaagtac aataaaatat
    18721 cagttttatc atttttagat tttaagaaat tcattgtaaa ctttaaattt gtaattataa
    18781 cgaaattttt aattgaatta tagaaaaaga aagtgagaag ctatggcaaa tttgggcttg
    18841 aaggagcgct atgatttcca gcagtggatt atcaaagatt tgagagataa gaatgactat
    18901 attcagcggg acgctacttg ctacgatcct agattagcca tggatgtgga actcctgtgg
    18961 gattttctga tggagaccca agaggagacc atggactatc tccttaaaaa actgagtaag
    19021 gagacaatcg tcaatctgat taataaagaa atcgtcaagg gtggcttttt attcgccttg
    19081 aaagaaggag tttttattga aaataaacaa cttcgtcttc tttatcgtaa acctgcgact
    19141 agttttaatg aaaaggctgt tcaacaatac caagtcaact gtctatctat tatggaagaa
    19201 gtggtttacg aggagagcga ccgcattgac cttgttatct ttatcaatgg attagcacta
    19261 tttgctatcg aacttaagtt taatcccagt ggtcagtctg ttcaggatgc tatcaggcag
    19321 ctcaagggac gcaatcctaa gaatcgtctt ttccgttttg aacagggagt cttggcttcc
    19381 tttgcagtgg ataccctaga agtctatatg acgacgcaat tgaaaggaca agaaacatac
    19441 tttctacctt ttaatgtggg gaaaggggaa ggtattgaga tgggaagtgg caaccctcac
    19501 aaccctgatg gtgtcgatac agactacttg tggcttgatg tcttgaccaa ggatagtatt
    19561 ctccagttaa tagatagttt tatctttttt gagatggatg agatggataa gcataattct
    19621 aaaaagaaga ccctgatttt cccgagatac catcagcgaa gagcagttag ccgtctccta
    19681 gaagacatga aagtcaacca tacagacagt aattatctga ttcagcactc agctggttca
    19741 ggtaaaacca ataccatagc atggttggct catagtttgg tatcgctcca tgatgaacaa
    19801 aatcaaaata ttgtggatac tgtattaatc gttacagacc gtatcgtagt tgatcgtcag
    19861 ttacaagaag cggtcaagga aatttcccac aagcctggag tggtcaaggt aatgggcgac
    19921 aaagaaacct ccagtgactt agcggatgcg attgcaggaa atacaaaaat catagctacg
    19981 acgattcata agtttgccca aatcaaccaa tctaactgga tgtctgtagg gaacactgcg
    20041 aaaaagaaat ttgccatcct gattgatgaa gctcacagtt caacgacagg atcctatatg
    20101 agttcggtta gtcaagtctt gacagaaaca gatacagaag atggaactat cgatgagatt
    20161 caagaagtaa gtgttgcgga cgctatcgag caggagattg ctcggacagg taagcaggac
    20221 aatgtctcaa tcattgcctt cactgcaact cccaaggcga caactctaca gctatttggt
    20281 acaacacaag cagatggttc taaagctcct tttgatgttt atagtatgaa gcaagctatt
    20341 gaggaaggtt ttattctaga tgttttagat aactatacga cttataagac ctattacaag
    20401 ctcaataaag cagtcgaaga agatcctgag ctaaaaacga ctcttgccaa gcgtaagatt
    20461 gcaaagtttg tagaattatc tgatgaaaat atcaatcaaa aggttgaaat tatcatggat
    20521 cactttatca gtcatgatat tatggctgaa ttgggtggtc aaggtaaggc tatgattgtg
    20581 acctctggtc gtgaggcagc agttaagtat caattagcct ttcaaaagta cttcaaagac
    20641 cacagcatta ccagtattgg aaccctgatt gccttttctg gcaaggttga ttatcaaggt
    20701 agtgaatata ctgagtcgca aatgaatcag gtcaaggaag attatttgaa agatcatttt
    20761 gatacggaag actaccaaat tctgattgtg gcaaataagt atcagacagg gtttgaccaa
    20821 cccaaactgg ttgctatgta tgtagataaa aagttgcgaa gtgttgctgc ggtgcaaaca
    20881 ttgtctcgtt tgaatcgtat ctatagaggc tacaataaga ggatctttat tcttgatttt
    20941 aaaaatactt atgacgatat tcgttcagct ttttctccct actaccgtga gactatttta
    21001 gcagatacag tcacacctag tgatgtcttg accttggatc ggaaaattga tgagtatggt
    21061 atcttggaca gtgatgttat tcatgagttt aatcaattct tataccaaga aaagagaaac
    21121 agcagagaaa agcaaaagat ggtttctctg ttaaatcaag gttatgatag agttagacgg
    21181 tttgatgaga aagaacaact ttctattcga aaggttattc gaggttttct tagaatgtat
    21241 actttcttga ttcaggcaac tgcttatcaa aatgaagttc tacacgaacg ttataattat
    21301 ctgcaaagtc ttgtcaagat gattgatgtt cgcattggag gagatgattt tacaatagca
    21361 gataagatcg tagtggacta tatgaaacat aagcaaacag gttccttcag gtcagtttct
    21421 gaattggaat atcatccaga gttaatactt accaagccaa gtactggagg tgttacgact
    21481 gaccaggaga agcgtttatc tgaaatctta gatgaaatta acgaacagtt ggatttggat
    21541 attgatcccc aagtcggtct aagtggagcg gtatccattc gtgaattgat gaaaaagaat
    21601 ccaagactaa agcaatctgc tcgtgtcaac tccagagaag acttcgtttt tgcttttgaa
    21661 gaagagattg acaatgctct tatagaagga tactctcaga gtcaagattt atttggtgct
    21721 ctattaaata atgattcttt caagaagaga ttagcagata tatttattga tgatgtattc
    21781 aaaagtttga agggatccga agaagtgtaa tcttaaaatt cacgctaatt tccccaaaac
    21841 atattctatt ttaggtttgt gaaaatcact tttttatggt agaatgtaaa agaatgtatg
    21901 tcattcagaa taacaataaa atgaggtaaa aacatggaaa tcatgtcgct tgcgattgct
    21961 gtttttgccg tcatcattgg tttagtcatt ggatatgtca gcatctcagc taagatgaaa
    22021 tcatctcagg aagctgcgga gttgatgctt ttaaatgctg aacaagaagc aactaattta
    22081 cgtggacaag ctgaacgtga agcggattta ctggttaatg aagccaaacg tgaaagcaag
    22141 tctcttaaaa aagaagcact attggaggcc aaagaagaag ccagaaaata ccgtgaagaa
    22201 gtggacgctg aattcaaatc agaacgtcaa gaactcaaac aaatagaaag tcgtttgacc
    22261 gagagagcta ctagcctcga ccgtaaggac gacaatttga cgagtaaaga acaaacactt
    22321 gaacaaaaag aacaaagtat ttctgataga gcgaaaaacc ttgatgcgcg tgaagagcaa
    22381 ttagaggaag tcgaaagacg aaaagaagca gagttagagc gtattggtgc cctgtctcag
    22441 gcagaagcac gagatattat cttggctcag acagaggaaa atttgaccaa ggagattgcc
    22501 agccgtattc gcgaagctga gcaagaggtc aaggaacgtt ctgataaaat ggccaaggac
    22561 atcttggttc aagctatgca acgtatcgct ggtgaatatg tagcggagtc aacaaactca
    22621 acggttcatc taccagacga tactatgaag ggacgcatta ttggtcgtga aggtcgtaac
    22681 attcgtacct ttgaaagttt gacaggtgtt gatgtgatta tcgacgatac gccagaagtg
    22741 gtgaccttgt caggatttga cccgattcgt cgtgagattg cccgtatgac tatggaaatg
    22801 ttgctcaagg atggtcgtat ccacccagct cgtatcgaag agttggttga gaaaaaccgt
    22861 caagagattg acaataagat ccgtgaatac ggtgaggcag cagcctatga gattggtgcg
    22921 ccaaaccttc atccagactt aatgaagatt atgggacgtt tgcagttccg tacttcatat
    22981 ggacaaaatg ttttgcgcca ttcgattgag gttgctaagt tggctggtat catggcgagc
    23041 gaacttggtg aaaatgcggc tcttgcccgt cgtgctggat tccttcacga tatcgggaaa
    23101 gccattgacc atgaggttga aggtagccac gttgaaatcg gtatggaatt ggcccgtaag
    23161 tacaaggaac ccccagttgt ggtgaatacg attgctagtc accacggaga tgttgaagct
    23221 gagagcgtga tagcagttat cgtcgctgca gcagatgcct tgagcgcagc ccgtccaggt
    23281 gctcgtagtg agtctcttga aagctacatc aagcgtctcc atgatttgga agaaattgct
    23341 aacggctttg aaggagtgca aactagcttt gcccttcaag caggacgtga aattcgtatc
    23401 atggtcaatc caggaaaaat caaggacgac aaagtcacaa tcttggctca caaagttcgt
    23461 aagaaaattg aaaacaatct cgattatcca ggaaatatca aggtaaccgt gattcgcgag
    23521 cttcgtgcag tagattatgc taaataaata agaaagagca gttgaaaaat tactgctttt
    23581 ttgttacact agatagaaag actgtaaagg ataatctggc tttttgccat tattctagag
    23641 aaatgttatt tcacagattg actaaaagga gacacaatgg cagaccgagg cttactaatc
    23701 gttttttctg gtccttcagg ggttggaaaa ggaacggtta gaagagagat ttttgagagt
    23761 tctgaaaacc aatttcaata ctctgtatcg atgacgacac gcgcacaacg tcctggagaa
    23821 gtggacggtg tcgactattt cttccgtact cgtgaagaat ttgaagagct gattcgtcaa
    23881 ggacagatgt tggaatacgc agaatatgtc ggcaactact atggaactcc tctgacttat
    23941 gtcaatgaaa ccttggacaa gggaatcgat gttttccttg aaattgaagt tcagggtgct
    24001 cttcaggtca agaaaaaggt tccagatgct gtctttatct tcctgacacc accagatttg
    24061 gatgaattgc aagaacgctt ggtaggtcgt ggaacagata gtgcagaagt ggttgcccaa
    24121 cgaatcgaaa aggccaagga agaaattgcc ctcatgcgtg agtatgatta tgcgattgtc
    24181 aacgatcagg tatccctagc tgctgaacgt gtcaaatgtg tgattgaagc agaacacttt
    24241 tgtgtggatc gtgtcattgg tcactatcag gagatgttac caaaatctcc aactacccga
    24301 taaaatttag aaaataggta caagcaaatg atgttaaaac cctctattga taccttgctc
    24361 gacaaggtta cttcaaaata ttcactcgta atcttggaag caaaacgtgc ccacgaattg
    24421 gaagcaggtg ccccagcaac tcaaggtttc aagtctgaaa aatcaactct tcgcgcttta
    24481 gaagaaatcg aatcaggaaa cgttacaatt cacccagatc cagaaggaaa acgtgaagca
    24541 gtgcgtcgcc gtatcgaaga agaaaaacgc cgcaaagaag aagaagaaaa gaaaatcaaa
    24601 gagcaaattg ctaaagaaaa agaagatggt gaaaaaattt aaggttgggg ggactcaatc
    24661 ttattttttc tattgcaaga atgtactgac aaggaggagg tgagaagatg gccctagcta
    24721 agattatcgt agatgtgccc ttgatgcaga cggaccagcc ctatagttac aggattccgg
    24781 aggaatttga gggaatgctg gaagttggga tgcgggttca tgtgcctttt ggtaagggca
    24841 atcgcctgat tcaagggatt gttcttggtt tggagtctca atcagacgaa gaagagatgg
    24901 agcaagattt aaaagatatt gccgaggtac tggatttttc tcccgttctc acgcaagaac
    24961 aactctggct tgctgaggag ttacgcaagt ccgtcttctc ctacaaaatt tccatcctca
    25021 aggccatgct tccgggattt ctgaattcta gctatgacaa gattctatat cctctggaag
    25081 gcttgagtca ggaagaacga gtacgcctgt ttggttcaga agattcactt gccttttctt
    25141 ctctggattt aggtaagcaa gctgaaatga tgcgtttgac tagaaaaggc ctgcttggtc
    25201 tggaatatca ggcagtcgat caaaagaagg tcaagaccca gtcttggtat gaggttgacc
    25261 atgttcaatt agaaggtgtt gagatttcta cacgtgccaa gaaaaagttg gaactgagag
    25321 attatctgct gtctcatcca gagagcgctt ccttggctag cttgttagag tcctactcgc
    25381 gagagcaagt caacttcttt gtggatcaag gtgctgttac catagtccaa aaggaagttc
    25441 aacgctcggc tgcttatttt gaaggaattg aagcaagtag acctttggag ttaaatccag
    25501 aacaaagaca ggcgcgtgat gcggttgtga gttctattgg cagttctcaa cctccctttc
    25561 tacttcaagg gattacagga agtgggaaga ccgaggttta cttgcagatt atccaaggta
    25621 ccctggataa gggcaagaca gctattttgc tggtacctga gatttccttg actcctcaga
    25681 tgaccgagcg ttttatagca cgttttgggg acaaggtagc cattcttcac tcaggattat
    25741 ccaatggtga aaagtatgat gaatggcgca aggtggagcg tggcgatgcc caagttgttg
    25801 ttggtgccag atctgctatc tttgctcctc tgaaaaatct gggtgtcatg attattgatg
    25861 aagagcatga agtggcttat aagcaggaca gcaatccccg ttaccatgcc agagaggtag
    25921 ctattttacg ggctcagtat aatcaagcaa ctctggtact tggatctgca acgccgagct
    25981 tagaaagccg ggcgcgtgct ggcaaaggcg tctatcaaca cttacgtcta acccaacgtg
    26041 ccaatccttt ggctacaatc cctgaggttc aagtgattga ctttcgagac tatatcggac
    26101 aaaatgagac gtcaaacttt acgcctcctt tgctagaggc tatccaagac cgtctggtta
    26161 aaaaagagca ggtggttctc atgctcaatc gtcgtggtta ttctagcttt gtcatgtgtc
    26221 gggagtgtgg gacggtggat acttgtccca actgcgatat ttctctgacc ttgcatatgg
    26281 ataccaagac tatgaactgc cattattgtg gtttctcgaa ggatattcct caggtctgtc
    26341 ctaactgtaa gagccacagt attcgttact atgggacggg aactcagaag gcttatgatg
    26401 agctagcaga actctttccc caagctcgca ttctgaggat ggatgtggat acgactcgaa
    26461 agaaaggtag tcaccaagcc ttgcttgacc agtttgggcg aggggaagcg gatattttac
    26521 ttggtactca gatgattgca aagggtttgg attttcccaa tgttacccta gtcggagttc
    26581 taaatgcgga tacggccttg aatctgcctg atttccgttc ttctgagaga accttccagc
    26641 tcttgactca ggtggcaggt cgagcaggtc gggctgaaaa agcaggtcaa gtcttgatac
    26701 agtcctacaa ttcgcagcac tatgctattc gatttgccaa ggatcaagat tacgaaggct
    26761 tttatgccta tgaaatggga atcagacgac aactctgcta tccaccttac tatttcacga
    26821 ttggtattac cctttctcac aagaaagaag aagaggtttt caaacgtgcc tatgaagtca
    26881 tgaacatttt gcggtcaggc ttgtcagaga ccagtcccat tctggggcca acgccaaaac
    26941 cgattgcccg tacccacaat ctctatcatt accagatttt aattaaatat cgtttagaag
    27001 atgagctggg gctgaccctc aaccaggtct tggccttgac tcaagaacgg gaaaatagtg
    27061 agctccgtct cagcattgac catgagccgc agcaattttt ataagaagga gaagatatga
    27121 caaaactaat ctttatgggg acccccgact tttcagcaac agtcttaaaa ggacttttga
    27181 cagatgaccg ttacgaaatt ctagccgttg tgacccagcc agaccgtgct gttggtcgta
    27241 aaaaagttat ccaagaaacc ccagtcaagc aggctgccaa ggaagcagga ctatctatct
    27301 accaacctga aaaattatct ggaagtccag agatggaaga acttataaag ctaggagcag
    27361 atggaattgt gactgctgct tttgggcagt ttctcccaag caaactcctt gatagcatgg
    27421 actttgctgt caacgttcat gcctccctcc ttcctagaca ccgtggtggt gcgcctatcc
    27481 attatgcctt gattcaaggg gatgaggaag ctggtgtgac catcatggaa atggttaagg
    27541 aaatggatgc aggagatatg atttctcgtc gcagcattcc gatcacagat gaggacaatg
    27601 ttggcgcctt gtttgaaaaa ttggcgctag ttggtcgtga tttgcttttg gacactctgc
    27661 ctgcctatat tgctggtgat atcaaacctg aaccgcagga tacgagtcag gttaccttct
    27721 ctccaaatat aaagccagag gaagaaaaac tggactggaa caaaaccaat cgtcaactct
    27781 ttaaccaaat tcgtggaatg aacccctggc ctgttgccca tactttcctt aagggcgacc
    27841 gctttaagat ttatgaagcc ctaccagtag aaggtcaggg aaatccaggt gagattctct
    27901 ctatcggcaa gaaagaattg attgtcgcaa cggctgaagg ggctctatcc ctcaaacaag
    27961 tgcagccagc tggtaagcct aagatggaca ttgcttcctt cctcaacgga gttggacgta
    28021 cattgactgt aggagaacga tttggtgact aaagtagaaa cggctagaag tttagctcta
    28081 gcagtgctag aggatgtttt tgtgaaccaa gcatattcaa atatcgcctt aaataagcat
    28141 ctaaagggaa gtcaactttt ggcagcagac aaggccttag tgaccgagct ggtctatgga
    28201 acggtagccc gtagactgac tctggaatgg tacctatccc actttatcga agacagagac
    28261 cagttagaca gctggctcta tgtccttctt ctcatgagtg cctaccaact ccgctatttg
    28321 gacaagattc cagatcatgc tgtggttaat gaagcagtgg aattggccaa actccgtaaa
    28381 aaaggcagtg aaaaattggt caacgctgtc cttcgccgta tcttgcgtga aggctggcca
    28441 gatattgcta gcatcaagcg aaaaaacaag cgtgactcca ttgcctattc tctcccagtt
    28501 tggctagttg ccaaactcaa ggaagaatac ggagaggaga gagcaaaagc catctttgaa
    28561 agcctgttag tgcgaaacaa agccagtatt cgtgtaacag acctaagtcg aaaagaggaa
    28621 atccaagcct tgttggaggc gaataattcc cttttagcaa ccactggtct cgttaaggag
    28681 caagggcatt ttgcagggca taatttgttt gcggatggag ccattaccat ccaagacgag
    28741 tccagtcagc tggttgctcc gacgcttgat ttacaaggtg atgagcgagt gcttgatgcc
    28801 tgtgcggctc caggtgggaa aacagcccat atagcctctt atcttacgac aggtcaggtt
    28861 actgctctgg acttgtacga ccacaagttg gatttaattc aagaaaatgc ccaacgtctg
    28921 ggagttgcag atcgggttca aactcaaaaa ttggatgcca gaaaggtgca tgagtttttt
    28981 gaccaggatt cctttgataa gattttggtg gatgctcctt gttcaggaat cggtcttttg
    29041 cgccgaaaac cagatatcaa atacaataaa gaaacggcag atttcgcgtc cttgcaggaa
    29101 attcagttag aaatattagg tagtgtttgt caaatactag gcaaaggtgg tataataact
    29161 tatagcacct gcactatcgt ctcagaggag aattttcaag tcgttaaggc ctttttagag
    29221 agtcatcccg agttcgagca ggtaaaacta gaacatgaat gtaaggatat catgaaagac
    29281 ggctgtatcc tcattacacc tgaattgtat ggaagtgatg gattcttcat cagtcaattt
    29341 cgcaagatat cggattagga aggaactgac acatggaaat ttcattatta acagatgttg
    29401 gtcagaaacg aacaaataac caagactatg tcaaccacta tgtcaataga gctggacgta
    29461 ccatgattat tttagctgat gggatgggag gtcatcgcgc agggaatatc gctagtgaaa
    29521 tggcggtcac agacctgggt gtagcttggg ttgataccca gatcgataca gtcaatgaag
    29581 tgcgtgaatg gttcgcccat tacctagaaa ttgaaaatca aaagattcac cagcttggtc
    29641 aggatgaagc ttacagaggc atgggaacta ctttggaagt ccttgctatt attgataatc
    29701 aggctatcta tgctcatatt ggtgattcgc gtatcggctt gattcgtgga gaagaatacc
    29761 atcagttgac gagtgatcat tctttggtca atgagttgct caaggctggt caattgacac
    29821 cagaagaggc agaagctcat ccgcaaaaaa atattatcac ccagtctatt gggcaaaaag
    29881 atgaaattca gcctgatttt gggacagtta tccttgagtc aggtgactat ctcttgctca
    29941 atagtgacgg cttgaccaac atgatttcag gcagtgagat tcgtgatatt gtaaccagtg
    30001 atattccttt agcagataaa acggagacac ttgttcgttt tgctaacaat gcaggaggtt
    30061 tagacaacat tacggttgcc cttgtttcta tgaacgagga ggatgcagaa tgatccaaat
    30121 cggcaagatt tttgccggac gctatcggat tgtcaaacag attggtcgag gaggtatggc
    30181 ggatgtctac ctagccaaag acttaatctt agatggggaa gaagtggcag tgaaggttct
    30241 gaggaccaac taccagacgg acccgatagc tgtagctcgt tttcagcgtg aagcgagagc
    30301 tatggcagat ctagaccatc ctcatatcgt tcggataaca gatattggtg aggaagacgg
    30361 tcaacagtat cttgcaatgg agtatgttgc tggactagac ctcaaacgct atatcaagga
    30421 acattatcct ctttctaatg aagaagcagt ccgtatcatg ggacaaatcc tcctagccat
    30481 gcgtttggcc cataccagag gaattgttca cagggacttg aaacctcaaa atatcctttt
    30541 gacaccagat gggactgcca aggtcacaga ctttgggatt gctgtagcct ttgcagagac
    30601 aagtctgacc cagactaact cgatgttggg ctcagttcat tacttgtccc cagagcaggc
    30661 gcgtggttcg aaggcgactg tgcagagtga tatctatgct atggggatta ttttctatga
    30721 gatgttgaca ggccatatcc cttatgacgg ggatagcgcg gtgaccattg ccctccagca
    30781 tttccagaaa cccctgccgt ccgttattgc agaaaatcca tctgtacctc aggctttaga
    30841 aaatgttatt atcaaggcaa ctgctaaaaa gttgaccaat cgctaccgct cggtttcaga
    30901 gatgtatgtg gacttgtcta gtagcttgtc ctacaatcgt agaaatgaaa gtaagttaat
    30961 ctttgatgaa acgagcaagg cagataccaa gaccttgccg aaggtttctc agagtacctt
    31021 gacatctatt cctaaggttc aagcgcagac agaacacaaa tcaatcaaaa acccaagcca
    31081 ggctgtgaca gaggaaactt accaaccaca agcaccgaaa aaacatagat ttaagatgcg
    31141 ttacctgatt ttgttggcca gccttgtatt ggtggcagct tctcttattt ggatactatc
    31201 cagaactcct gcaaccattg ccattccaga tgtggcaggt cagacagttg cagaggccaa
    31261 ggcaacgctc aaaaaagcca attttgagat tggtgaggag aagacagagg ctagtgaaaa
    31321 ggtggaagaa gggcggatta tccgtacaga tcctggcgct ggaactggtc gaaaagaagg
    31381 aacgaaaatc aatttggttg tctcatcagg caaacaatcc ttccaaatta gtaattatgt
    31441 cggtcggaaa tcctctgatg tcattgcgga attaaaagag aaaaaagttc cagataattt
    31501 gattaaaatt gaggaagaag agtcgaatga gagtgaggct ggaacggtca tgaagcaaag
    31561 tctaccagaa ggtacgacct atgacttgag caaggcaact caaatcgtct tgacagtagc
    31621 taaaaaagct acgacgattc aattagggaa ctatattgga cggaaatcct ctgatgttat
    31681 tgcggaatta aaagagaaaa aagttccaga taatttgatt aagatagagg aagaagagtc
    31741 cagcgaaagc gaaccaggaa cgattatgaa acaaagtcca ggtgccggaa cgacttatga
    31801 tgtgaataaa cctacccaaa tcgtcttgac agtagctaaa aaagttacaa gtgttgccat
    31861 gccgagctac attggttcca gcttggagtt tactaagaat aatttgattc aaattgttgg
    31921 gattaaggaa gccaatattg aagttgtaga agtgtcgaca gctcccgctg gaactgctga
    31981 aggtacagtc gttgaacaga gtcctagagc aggtgaaaag gtagacctca ataagactag
    32041 agtcaagatt tcaatctaca aacctaaaac aagttcagct actccttaaa atcagatgga
    32101 taatcaaaat gagtaatcaa tctttgtcat gattttgtgg caaagatttt ttttgagtcc
    32161 ggatttgtga tagaatagag ggagttgata aaaggaggca agcatggaag agtcaaaaga
    32221 attaaatgcc gtcatcgatg tgattatgct agcggggact attctcctta aaagtggctc
    32281 agaaatccat cgtgtagaag ataccatgat tcggatcgcg cattcgcagg ggattgtgga
    32341 ttgcaatgtt cttgccatgc ctgctgctat ctttttctct attgaaaata ctaatatttc
    32401 gcgcatgaag cgcgtgacct cctcttctta taacattgaa aaagtctgcg atgtgaacca
    32461 gatttctcgt cagctggttg gggggcagat tgatttagaa acagccttta agcaattgac
    32521 ggccttgcaa gcccaacccc ttccctatac taagttgcag gtaactctgg ctgcgacctt
    32581 tagtgctcct ttcttttcaa ttatgtttag tggaaatatt tacgacgcac ttggggcagg
    32641 agtggctact ttatttggct ttgccttttc cctctatgtg gagaagttta tccgaattcc
    32701 ctttgtgaca gcctttgctg gagcctttgt ctttgggatg attgcccagt tttgggctcg
    32761 ctacacaggc tttccttcaa cagcagattt gattatagct ggtgcggtca tgccgtttgt
    32821 accagggatt gccttgacca atgcggttcg tgatattatg accaaccaca taaactctgg
    32881 tatgagcaag atgtttgaat ctctgctcat tacccttgct ttaggggcag gaacttctgt
    32941 cgccttggta ttgatgaact aatatgacac taacaacctt tttattacaa gcagtagcaa
    33001 gtcttcttgc cattatcact tttctaatcg tactcaatgt gcaacgctct atgctcttac
    33061 ctggagggat tttgggcatg gctgtctggc tgatttatct cttgctcaag gaaccgacca
    33121 atgttattgt ggctaccttt attgccgcca taatcggttc ttgtgtcagc cagattttaa
    33181 gtattcttta taagactcct gctgtggtct ttatcttggc cattttggca ccgctggttc
    33241 cgggctacct ttcttatcgg acaactgcct tttttgtgac aggagactat aataaagcgc
    33301 tggcaagtgc gaccttggtt gtcatgctgg ctttggtaat ctctattgga atagctagcg
    33361 gaacagtgat tctcagactg tatcattata taaaaacaca tcgagtatcg tagattttac
    33421 agaaataaaa gaattttctg aaaaatgaga taaatatagt aacaacgctt tctatatgtg
    33481 cgagaatatc gaacttatga agaaattgcg gctgattttg gtatccacga aagcaactta
    33541 ctccgtcgga gccaatgggt tgaagtaact cttgttcaaa gtggtgttac gatttcaaga
    33601 actcctctca gttctgagga cacggtaatg attgatgcga cggaagtaaa aatcaatcgc
    33661 cctaaaaaaa caattagcga atgattctgg taaaaagaaa tttcacgcta tgaaggctca
    33721 agcgattgtc acaagtcaag ggagaattgt ttctttggat atcgctgtga actattgtca
    33781 tgatatgaag ttgttcaaaa tgagtcgcaa aaatatcgga caagctggta aaatcttggc
    33841 tgacagtggt tatcaagggc tcatgaagat atatcctcaa gtacaaactc cacgtaaatc
    33901 cagcaaactc aagccgctaa cagttgaaga taaagcctgt aaccatgcgc tatccaagga
    33961 gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatga tttcaacaac
    34021 ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg atattatcaa
    34081 tcatgaacta ggattctagt tttgcaggaa gtctactatt ttccttattg tctgtaagtc
    34141 tatggacctt gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg
    34201 gatggcaaga gcatcaattg attgctgaga aggttagtaa aacacttgac aagacatttg
    34261 ataaggatgt cagagaaatt ccgaccagtc agttttatca agaatttgta gatgagatgg
    34321 gaaggactta ctcaggaaat ttgatcctcc aggagctgat aactgtgaat gaagcttata
    34381 aagctactta tatcggtgaa ctctatatca actaatcatt ctttaaaatt atgaccaata
    34441 agaggcttga tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa
    34501 tagtatagaa cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt
    34561 gataagattg gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg
    34621 aggggaattg accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg
    34681 cccctaactg aggacatcgt gaccttggcg gccagtgcta gtgactctat tttaactgag
    34741 caagaaagac aagaagttga catggtcatt gtggcgaccg agtcaggaat tgaccagagt
    34801 aaggctgcgg ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc
    34861 gagattaaag aagcctgcta tggagcgact gctgcccttc attatgccaa attgcatgtg
    34921 gaaaattctc cagagtcgaa agtcttggtc atcgccagtg atattgccaa gtatggaatt
    34981 gaaactccag gagaaccaac tcagggtgct ggaagtgtgg ctatgttgat tacacaaaat
    35041 ccacgcatga tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc
    35101 tggcgaccaa attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac
    35161 ttggatagtt tgaaaacgac ttggcttgaa taccaaaaac gctaccagct taccttagat
    35221 gattttgcgg cggtttgctt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa
    35281 aaaattatgg ataagaactt gcctcaagag aaaaaagacc tcttgcaaaa ccattttgac
    35341 cattctattc tctatagtca aaaggtgggg aatatctaca caggttcact tttccttgga
    35401 cttttgtctc tcttggaaaa tacagatagc ttgaaagctg gggataaaat cgccctttat
    35461 agttacggaa gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa
    35521 gcttatttgg ataaagaccg cttgaacaag ctcaaccaac gaactgacct atccgttgca
    35581 gactatgaaa aggtcttttt tgaggaagta gacttggatg aaacaaactc tgcccagttt
    35641 gctggctatg aaaatcaata ttttgccttg gttgaaattc tcgaccacca acgccgttat
    35701 agcaaggttg aaaaataatg aagataagtt ggaatggatt ttctaaaaaa tcataccaag
    35761 agcgcctcga gctgttaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg
    35821 agcaggatga acagatgagt gtgactgtgg cagaccagct gagtgagaat gtggtgggaa
    35881 ctttttctct gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg
    35941 ttccctatgt gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca
    36001 tcaagcatgt aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtat
    36061 ccctttatca agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg
    36121 agctcttgga gcttgccaat caagcctatc cttctatcgt taaacgtgga ggtggggcgc
    36181 gtgacctgca tgtcgagcag ataaaaggtg aaccagactt tctcgttgtt tatattcatg
    36241 tcgataccca ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac
    36301 cagtcttaga agaactcagt cagggacaga gtctcatggg aatcctgtcc aactacgcga
    36361 ccgattctct ggtgactgca agctgtcgca tcgcctttcg ctacttgagc agccaaaagg
    36421 atcaaggacg agagattgcg gagaaaattg cgttggctag tcagtttgcg caggctgatc
    36481 cttaccgagc tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg
    36541 ccactggtaa tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg
    36601 gacgttatca aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg
    36661 agatgaccct gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg
    36721 tagctctcag tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg
    36781 tgtccatcgg tcttgcccaa aattttgcag ccctcaaagc cttggtaagt acgggcatcc
    36841 agcaaggcca catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat
    36901 ctgaagttgc tcccctagtc gagcagctta tcgcagataa aacctttaac ctagagacag
    36961 cccagcgcta tctcgaaaat ttaagatcat aaaaaactca gacgaatcgg tctgagtttt
    37021 cttgtgttta aatacttttt cctggtaata gtgtaactgg taagaagtaa ccagttgtgg
    37081 cgacttcctt gccttcaatc ttttgcaaga gaagatcaat agtgagacaa gcaatctctt
    37141 ccaaaggttg cttgatagta gccaattgag ggtagtaatt ttcgataaag taggtcccat
    37201 catagccgat gaccttgagc tcttttggga cagaaatgcc caattcttga gcgattttaa
    37261 tgaccagaat agctgtcaaa tcatccgaag caaaaatggc atctggtttt tcccgggtca
    37321 agatattctt gatttccatt tcttttctga caggagaaaa gtcactggaa acattgataa
    37381 taggagcttt tgggagtacg gatgcaaaac cagcgtggcg cagtccggtt ggcgaattgg
    37441 aattgtcatt ccctgtaatc atgatgatag actgggcacc tgtcttgacc aaggtttggg
    37501 cagcaagaac cccaccagca tagttgtcag aggagacgac agggatgtct ggcgataggt
    37561 ttcggtcaaa ggaaataatc ggcgctgtca cacgattgta gtcttcgatt cctaggttgt
    37621 gactaccaga aatgatgccg tccacctgat tggcttccaa catttcgatg tattcacgtt
    37681 ccttctcaga atcatgttca ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt
    37741 ggtgttccaa tttatcaatc aattctgcat agaaaacatt ggaaatattg gggaaaatca
    37801 agccgattaa cttagctgat tttccttgca gactacgagc caggttgttg ggtttatagc
    37861 ccaattctcg catggcttca ttgacttttt ggatggtttt ctcagataga tacccttttt
    37921 tattgataac ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg acatcagtta
    37981 gttttgcgac cataatctaa ttcatagtaa gttccagttg ggtttccaga tttgatcagg
    38041 ataccatttt ggtccgcatg tgggaagaca cgaccagaaa atactttttc tcctttattg
    38101 atgaaaattt caaagacaga gttatcgatg aagattgtag cagtagtagc ctgattctcg
    38161 atagggcaag aacgagttgt cccaaattct tgggcatact gttctccagc ctggctacga
    38221 tccactgtca cttgaccgtt tacaaggtca aagttgattg aaagtccctt accttcttta
    38281 tcagcaagta agacaatctc gctctggcta ttagcttcca agttgagttc aagttcgtaa
    38341 gtgttcttgg tttggaaacg gtttgagaag gcttcttcag aagcacgaag gtccttaata
    38401 gcagcgactg gatactggta gagcttgtcg tctttgatag tgagttcctt gaccaaagag
    38461 aaggttcctt ggtggtcaaa acggtcagat gggtaagaaa catctggcaa accaagccag
    38521 ctaactgcta gagcacgccc atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa
    38581 ccgtaatcca tgttttgaag ttgagacaca tctaccattt tggcattttt agggtcaaag
    38641 gaagccccaa tcttatacat atttggaaag atattatcgt agtctagaac tttcttatcc
    38701 aatccttgtg gacagtagag aaggacaggc tgttcctcta caaagaccag attaggacat
    38761 tccatcatgt aggcagtacg gtcgttagca aagtcaaggt cgccaactgc ttgccagttt
    38821 gtgtagtcgt tattgacagc cttgtagaga cgaacgaaac cttttttctc caagtcttgt
    38881 ccgccgacaa tggcataata ttgaccctga aagttaaaaa tttgtggatc gcggaagtgg
    38941 tcagtagagt ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc
    39001 ttgtccatca aagcaccgat ttggtatggg tgacggatcc agttttcatc gcgaacattt
    39061 cctgtataaa ataggaataa gttatcgcca aattgcatgg cagaaccaga gtaggcaccg
    39121 tgactatcta atggagtatc tggcaaaact ttgactccag tttctctaaa gtgaaccaaa
    39181 tcatcacttt ctagctgtgc ccaagatttt aaaccgtggg ctgcaccaaa aggaaaattc
    39241 tggtaaaaga ggatccactt gccatcaaag taagaaaagc catttgggtc gttgagaagt
    39301 cctgtttttg gctcaacatg gtaatgagta tgccatggag attgtgccat attttccttt
    39361 atatgttgaa tttcttcttg cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc
    39421 cattccattc attcctccaa aaatcttatc acttttaata gtaactgttt tcgataaaaa
    39481 atgcaagcct tttatgttaa aaaagagaaa aaactgtcaa acgattatca taaaataaat
    39541 acaggaaatc aattaaattt ttacgaaaat gtgaaagata atgaaataaa agacttttta
    39601 accaaggttt caaacttatt tttcaaggaa tctctgatga aacagtcaaa aacaatcaat
    39661 ctaaagcttg cccgctaagt ggatagaata ttttttctgc aaaacgcttg acatattttt
    39721 aaaacatgat aaaataatag tcgtaagggc gaataaaatc gctttcaaac aagaacaaaa
    39781 tgttatataa ggagattttt gcaaatgaac aatcaggaaa ttgcaaaaaa agtcatcgat
    39841 gccttgggcg gacgtgaaaa tgtcaatagt gttgcccact gtgcgactcg tctacgtgtc
    39901 atggtcaaag atgaagagaa aatcaataaa gaagtgattg agaacttgga aaaagttcaa
    39961 ggtgctttct ttaactcagg gcaataccaa attatctttg gtacaggtac agttaacaaa
    40021 atgtacgatg aagttgttgt acttggctta ccaacatcat ctaaggatga catgaaagca
    40081 gaagttgcta aacaagggaa ctggttccaa cgtgctatcc gtactttcgg tgatgttttc
    40141 gttccaatca tcccagttat cgtagcgaca ggtctcttca tgggtgtgcg tggtcttttc
    40201 aacgctcttg aaatgccact tccaggtgac tttgcaactt acacacaaat cttgacagat
    40261 acagccttca tcatcttgcc aggtttggtt gtgtggtcaa ccttccgtgt atttggtgga
    40321 aatcctgccg ttggtatcgt tcttggtatg atgcttgtct ctggctcact tccaaacgct
    40381 tgggcagttg ctcaaggtgg tgaagtaaca gcgatgaact tctttggttt catccctgtt
    40441 gttggtttgc aaggttccgt tcttccagcc ttcatcatcg gggttgtcgg agctaaattt
    40501 gaaaaagctg tccgcaaggt tgttccagat gtcattgacc tcttggtaac accattcgtg
    40561 acacttttgg tcatgtctat ccttggactc tttatcattg gaccagtttt ccacgttgtt
    40621 gaaaactaca tccttattgc tacaaaagcg attcttagca tgccatttgg tcttggtggt
    40681 ttcttgattg gtggggttca ccaattgatc gtcgtgtcag gtgtgcacca catcttcaac
    40741 ttgcttgaag tgcaattact tgctgctgac catgctaacc cattcaacgc tatcatcaca
    40801 gctgctatga cagctcaagg tgctgctact gttgcggttg gtgttaaaac aaaaaatcca
    40861 aaactgaaaa cacttgcttt cccggctgct ctttctgcct tcctaggtat tacagagcct
    40921 gctatcttcg gggtgaactt gcgcttccgt aaaccattct tcctttcatt gattgctggt
    40981 gcaatcggtg gtggattggc ttctatcctt ggacttgctg gtactggtaa tggtatcacc
    41041 atcatccctg gtacaatgct ttatgttggt aacggacaac ttccacaata ccttcttatg
    41101 gtagctgtat catttgccct tggttttgct cttacttaca tgtttggtta cgaagatgaa
    41161 gtagacgcaa ctgcagctgc aaaacaagct gaagtggctg aagaaaaaga agaagttgcg
    41221 ccagcagctc ttcaaaatga aacacttgta actcctatcg tcggtgatgt tgtcgctctt
    41281 gctgatgtca atgacccagt cttctcaagt ggagctatgg gacaaggtat cgctgtgaaa
    41341 ccaagtcaag gcgtggtcta tgcactagct gatgctgaag tttcaattgc ctttccaaca
    41401 gggcacgctt ttggtttgaa aacaagaaat ggtgctgaag ttttgattca cgttggtatt
    41461 gacactgtat ctatgaacgg tgacggtttt gaagcaaaag ttgctcaagg taataaggtg
    41521 aaagctggcg atgttcttgg aacatttgac tcaaacaaaa tcgctgcagc tggacttgat
    41581 gatacaacaa tggttatcgt tacaaataca gctgactacg tttcagtagc tccagtcgca
    41641 acaggttcag tttcgaaggg ggatgctgtg atcgaagtga aaatctaatc aatcctctct
    41701 aatgtgaaaa cgaacaaatg acatgtttgt tcgtttttat tagatagtaa gatttacaga
    41761 ggaaaatcta aaaaatagag acatttagac tttcgaagta tgctataata aagaaaataa
    41821 aaacaagagg tttatcatga caaaattata tggaagcttg gaagcgggcg gtacaaagtt
    41881 tgtctgtgct gtcggtgatg aaaactttaa cgttgtagaa aaaacacaat ttccaacaac
    41941 aactccaatc gaaacaatcg ataaaaccat tgagttcttc tcaaaattcg ataaccttgc
    42001 tggtcttgca gttggttcat ttgggccgat tgatattgac aaaaactcaa aaacttatgg
    42061 ctttatcacg acgactccaa aaccaaactg ggcaaatgta gacttgcttg gtgcccttcg
    42121 tcgcgcccta aacgtgccaa tgtacttcac aacagacgta aacagctctg cttacggtga
    42181 aatggttgcc cgtaacaatg ctggtggtcg tatcgaaaac ttggtttact acacaatcgg
    42241 tacaggtatc ggtgcaggcg tcatccaacg tggtgagttt atcggtggtg tgggtcaccc
    42301 tgaaatgggt cattattatg ttgctagaca cccaatggat attgaaaaag agtttaaggg
    42361 tgtttgtcct ttccataagg gatgtctaga aggttatgca gctggtccaa gtttggaagc
    42421 tcgtacaggt gtacgtgggg aaactattga actcaacaac cctgtttggg atgttcaagc
    42481 ctactatatc gctcaagctg cggttaatgc gacagtgact ttccgcccag acgtgattgt
    42541 ctttggtgga ggggtcatgg ctcaacaaca tatgctggac cgtgtccgtg agaaatttac
    42601 atctcttctt aatggttacc taccagtacc agatgtgcgt gactatatcg tgacgccagc
    42661 agtcgcagga aatggttctg ccacacttgg gaactttgtt cttgcaaaag aagtttcaaa
    42721 ataaagcaca aaatccgctt gggaaaccaa acggattttg tggttgaaaa caatattttt
    42781 gagcctttcc ttaagtgatt acggacggta gcgactttct tcgaaattcc atacctaaac
    42841 tttgagacac taggctcaaa gtttccgaac acctgaaacc attagatttc aggtgtttct
    42901 atcacggcgg aaaggctagg taagtcctcg cttcactatc gaaaaatatg catgatttcc
    42961 ataccaaagt atatttagta tcaagttata gttaatctac gctttaaaaa tccacttggg
    43021 aaaccaaacg gattttttac gtgtcaaagc atttgccaga aaaagtcaat aatataggtc
    43081 agaccgtagg tataaaccac gagggtaaag ggtttggtca gaatgatgat ggtcatgtag
    43141 cgcttgaaac tcatcttggt cagggcagcc agcatacaga gaaagtcagc tgggctaatg
    43201 ggccaaatca tcataaaaat aaagaagcgg tcaaaacgat tgcccttatc tagccagccg
    43261 atgtacttgt cgtaggtgcg cttgctgacg acagactgga caaaggcagc tccgtatagg
    43321 cgcactagat aaaagataat ggcacagcca atcacgatgc cgatatagtt gtagatagtc
    43381 ccgatgatgt gcccgtagat aaagacccca gccaccgagg tcaaggcccc tggaatgata
    43441 gggacgacag tctgtaaaat ctgtaaaaag ataaagagag gtggacccca gatgcctgcc
    43501 tgctggataa aggcagagag ggtttccttg gattgtaaaa tcccagcctg ataagcccaa
    43561 atacagaaaa tcaaactccc aaccccaccg acaatcgatg agatattgat aactcgctgc
    43621 agaaggggag aaacagcttt catttgttta tcctgtgaca tgtaaactcc tcatagatag
    43681 tatatttcta ctataccata ttttggagga gaaaggggga atgagtcttt tttgataagg
    43741 aatagaaagt aaatagccct tcgagactta gaataggtct gtcaactaaa ggttatatgc
    43801 attctaggtt tcgaataatc gcaattccat aaatttaaaa gcattctaag tttcgaatag
    43861 cttatctgag ataattttga ggcattcgcg ctttcgaata gtcattttcc ctaaagttta
    43921 gatgtattct gaagctagaa agactaaaat ctaaaagtag taagagtctc tctctgatgg
    43981 acgtaattta tggctagtat gaatcctttg aattgttagt taattttaat attaatcagt
    44041 tctgaaataa ttactaaata tagttagatg gtgaattaat tattgctaaa tttcaagttc
    44101 aagttcaagt tagtcatcca gaagtcttct ctgggggact tgtagttcaa gcatttttta
    44161 ggatagttgt taatccactt ttcgatgaat gcgacttcct ttgtagtcgt tttcttagtt
    44221 ccctgaggta accatctatg aatgaacttg ttgtgatttt tattagatcc tatagtggtg
    44281 tgcataatag atataataga ttgaaactag aatagtacgc atctacttct aaaacattgt
    44341 tagaaatcga tttgactgtc ccgatctatt tgtcctgttt ttatttcatt ttactatata
    44401 atccttagaa aacatatcgg acaagcggtt gaattccgtt ccgtccatta gtagataaag
    44461 gattactcct tcttgaaatg acagatgaac ttgtttctta taaaaatgtt gtctgaaact
    44521 attcgctttt ttccagaagt tttagaggaa gaaaacttta tgaggaaaaa ggagttactc
    44581 aaataacaat tcaggattaa aaatagacag ttgaggagcg gaaggtataa attaagtttg
    44641 ctactgtata atggatttat cactaatact cttcgaaaat ctcttcaaac cacgtcagct
    44701 tcgccttgcc gtagatatag ttactgactt cgtcagttct atccacaacc tcaaaacagt
    44761 gttttgagct gacttcgtca gttttatctg caacctcaaa gctgtacttt gagcagccta
    44821 cggctagctt cctagtttgc tctttgcttt tcattgagta taaaagtgct ccaggccata
    44881 ttttacacag caatagtctt ctaaaaatgg acaaaaacat tgtaaaggct atcaaaaagg
    44941 agtataatga gtgcaagaaa tttcggaggt gaaagatgct agaagtaaga agtctagaga
    45001 aaagttttgg ctccaagcaa gttttgtttg gtattgactt tcaagcgcga ccaggtcgta
    45061 ttttgggact agtcggaaaa aatggtgctg gaaaaacaac gattttccat agtattttga
    45121 aattcctaga atatcaggga gaaatcggtc tggatggtca ggatattcgt caggagacct
    45181 atgctcggat tggttatctg cctgaagaac gcagtctcat gcctaaattg acagttcttg
    45241 aacaagttcg ctacttggcg actctaaaag gcatggatgc caaagaagtc aaagaaaaac
    45301 tccctcaatg gatgaagagg ttggaagtga aaggaaagct gacagataaa atcaagagtc
    45361 tgtcaaaagg aaatcagcag aagattcagc tcattattac tctgattcat gaaccagacc
    45421 tgattatctt ggatgagcct tttagtggat tggacccagt taatacagaa ttgctcaaac
    45481 aagtcatttt tcaggaaaaa gagcgcggag caaccattat cttttctgac catgtcatga
    45541 ccaatgttga ggaactttgt gacgatattc tgatgatccg agatggccgt gtggtcttgc
    45601 acggaccagt tcaggatgtc cgcaatcaat acgggaaaac gcgtctcttt gtttcaagtg
    45661 aacgaagcaa ggaagaattg gaaaatcttc ctcatgtcaa acaggtgagc ttgaccaaac
    45721 aaggcagttg gaaattgatt ttggaggatg agagcgctgg aagggaactc ttcccaatct
    45781 tgactcaagg tcaatatatc gcaacatttg accaacaagc gccaactatc gatgaaatct
    45841 ttaaactaga atcaggagtg gaagtatgag aaatatgtgg gttgtaatca aggaaaccta
    45901 tcttcgacat gtcgagtcat ggagtttctt ctttatggtg atttcgccgt tcctcttttt
    45961 aggaatctct gtaggaattg ggcatctcca aggttcttct atggctaaaa ataataaagt
    46021 ggcagtagtg acaacagtgc catctgtagc agaaggactg aagaatgtaa atggtgttaa
    46081 cttcgactat aaagacgaag caagtgccaa agaagcaatt aaagaagaaa aattaaaagg
    46141 ttatttgacc attgatcaag aagatagtgt tctaaaggca gtttatcatg gcgaaacatc
    46201 gcttgaaaat ggaattaaat ttgaggttac aggtacactc aatgaactgc aaaatcagct
    46261 taatcgttca actgcttcct tgtctcaaga gcaggaaaaa cgcttagcgc agacaattca
    46321 attcacagaa aagattgatg aagccaagga aaataaaaag tttattcaaa caattgcagc
    46381 aggtgcctta ggattctttc tttatatgat tctgattacc tatgcgggtg taacagctca
    46441 ggaagttgcc agtgaaaaag gcaccaaaat tatggaagtc gttttttcta gcataagggc
    46501 aagtcactat ttctatgcgc ggatgatggc tctgtttcta gtgattttaa cgcatattgg
    46561 gatctatgtt gtaggtggtc tggctgccgt tttgctcttt aaagatttgc cattcttggc
    46621 tcagtctggt attttggatc acttgggaga tgctatctca ctgaatacct tgctctttat
    46681 tttgatcagt cttttcatgt acgtagtctt ggcagccttc ctaggatcta tggcttctcg
    46741 tcctgaggac tcagggaaag ccttgtcgcc tttgatgatt ttgattatgg gtggtttttt
    46801 tggagtgaca gctctaggtg cagctggtga caatctcctc ttgaagattg gttcttatat
    46861 tccctttatt tcgaccttct ttatgccgtt tcgaacgatt aatgactatg cggggggagc
    46921 agaagcatgg atttcacttg ctattacagt gatttttgcg gtggtagcaa caggatttat
    46981 cggacgcatg tatgctagtc tcgttcttca aacggatgat ttagggattt ggaaaacctt
    47041 taaacgtgcc ttatcttata aatagaagag ccttgcgaaa gcgaggtttt taaaggtgaa
    47101 aagggtggaa tcacgaacct aattatgtac acattatgta aacaagttgc ttgaaaactc
    47161 aattgtatag tgaactgaat ctggaatagg ataatattac ttctaaaaca ttcttataaa
    47221 ttgatttgaa ttccaaaatc ccatcgttcc gttcttattt cattttgcga tatagtgaaa
    47281 ggaaataagt cagctcacaa aaaacgcata atatcaagga tttttaacac ctgatactat
    47341 gcgttttcta attttaaaga ctttttgcct ggtctctttt gttctatgag tatgttacat
    47401 atctaggtaa aaattattta aagcaaatta accttatttc tcaagatgta gtaggttccg
    47461 agataaaaga tagctatgaa tatgagttct ttaacaatgg ctatacctgc tcccatatag
    47521 aaatggtcat tgagtcctac cagtgaattg acatagaaat tagaactaag attgaagaaa
    47581 agttcaataa atccaatgac gatttggata ccaatgtagg ctgcaacagc gagtgctgta
    47641 cggtattcat tgaaaagctg tccaatggaa atagccaggt agatgcatag gattcctgaa
    47701 atggtattta gtaggaagga tatacctgta agaaagatct gagggagatg tgtttctaca
    47761 aatgtaatca cataagaaag aggaatccat tctggagctg ttaaagccag aataataaca
    47821 gcacttagag ccaatacagc ggtgctaatc aatgaccaga taaaggcacc gattagtttg
    47881 gctgtgatga tatggtgttc agaaactggc aaggtcaaag tcagatagcc ttgtcggtcg
    47941 tagacactac ctttgaagcg tttaataatc aagaaaatgg ttgaaatcgc aagtgtaagc
    48001 atcaagccac caaagactgt agctagaaaa agtagcatag tagcctgact ttcttggtaa
    48061 ggtagatttt taaagccttg tgtctgtatt ccgatgaggg cagaaaggac tagcacggct
    48121 gcgtagaggg ctaaatacca cttgttaaca tttttaaatt cgtagtgaac taaattccaa
    48181 aacataaata atctcctttg cttaggcctt aaattcctga cggaagagtt ggtcaatgga
    48241 ttcacctgac tcgtagcgaa tatcatctac atttccttga cggacgactt ttccgtcttt
    48301 taggaagaca atttcatcca agattggctc gatatcagaa atcaagtggg tagaaatcaa
    48361 aacggtagaa gttggtgagt agttgttgat aatggtattg aggatataag cacgggctgc
    48421 tggatccacc ccaccaatgg gttcatccaa aacatagaga cgagcatcac ggctcataac
    48481 caaaatcagt tgaacctttt ctttgtttcc ttttgatagt ttcttgagac gactattttc
    48541 atcaatgccc aggtctgcaa gtagatgatg agcgcgttca agattgaaat ctttatagaa
    48601 ggtcttgaag taggttaggg cttctttgac cttcatttgc tcattgagat aggtcgtatc
    48661 aggcaaataa gctacaacgg ccttggttgc tgggcttggg tccatgtcgt tgatgaggac
    48721 acgtccttga tctggttgta agaggccatt aattagttta atcagggttg tttttcctga
    48781 gccgtttggc ccaagaaggc cgacaatttt tccagctgga atgtcaagag aaacattttc
    48841 aagggctggt gttgctccat atgatttgga tacattttca aatgctagta atgacatagg
    48901 cttaaactcc tttaatataa tcactgacta cgcctggtag ttcttctttt tcatagccaa
    48961 aatgggtcat ggaggaaacg aagtgttcca attcttcttc tgataattgt ttgcgtgact
    49021 gagcgattag ctccttatcc ttagtcacaa atcgtccagt tgttcgcttg ctgtagacaa
    49081 atccttctcg ttcaaggtct gataaggctc tttggatggt attgggattg acactagcct
    49141 cgctagctag ctccctcacg gttggaagtt gttgattggg ttccagtgta tgggaaacaa
    49201 tctgaagttt gattttctcc ataatctgta aatagatggg ttttttgttg tcaaatgtcc
    49261 aggacatctt agtctccttt ctcttattct tttgtcttaa ttaaataata caacaaaaca
    49321 aaaaacttgt caagcaaaaa gaagaattgt tttgggaatc gcttaaaaaa tggtataatg
    49381 aaaagaaaac gataaggagg gaaaggatgc gttgtccaaa atgtggggct accaagtcaa
    49441 gtgttatcga tagtcgccaa gcagaagaag ggaacaccat tcgtagaaga cgtgagtgcg
    49501 acgaatgcca acaccgtttt acaacttacg aacgagtaga agaaagaacc ttagtggttg
    49561 ttaaaaaaga tggcacacgg gaacaattct ccagagataa aatctttaat gggattatcc
    49621 gctcagccca gaaacgtcct gtgtcaagtg atgaaatcaa catggtagtc aatcgtatcg
    49681 aacagaaact ccgtggtcga aatgaaaatg aaattcaaag tgaggacatt ggttcactcg
    49741 tcatggagga gttggctgaa ttggacgaga ttacctatgt acgttttgct agtgtctatc
    49801 gtagttttaa ggatgtcagt gagttagaga gcttgctcca acaaatcacc cagtcctcta
    49861 aaaagaaaaa ggaaagataa atgaagccaa ttgaccgttt ttcttatcta aagaataatc
    49921 gggtgtcgca agatacctca tctctggtac agtgctacct cccgattatc ggtcaggagg
    49981 cactgagcct ttatctttat acaatcagtt tttgggataa tggtaggaag gaatatcttt
    50041 tttcaagtat cctcaatcat ctcaactttg ggatggatag actgataaaa tcattgaaaa
    50101 tcttatctgc ttttaatctc ttgaccctct atcaaaaggg ggatgtttat cagctagccc
    50161 tccatgctcc tctatctagt caagacttct tgaggcatcc tgtttatcgc agactcttag
    50221 agaaaaagat tggcgatgta gctgtggagg atttgaaagt tgaaagtgct gatggtgaag
    50281 aaatacctgt ctcactcaat caagtctttc cagaattggc agaactaggc agtcaagaag
    50341 accttggtct caagaagaaa gtggccaatg attttgactt ggaacatttt cgccagctga
    50401 tggctcgaga tggacttcgt tttgcggatg agcagtccga tgtcttaaac ctctttgcta
    50461 ttgccgagga gaagaaatgg acttggtttg aaacctatca attggccaag tcaacagctg
    50521 tttctcaggt tatttcaacc aaacgcatgc gtgaaaaaat tgctcaaaaa ccaatttcct
    50581 ctgactttag tcttaaggaa acaaccatta tcaaagaagc caaaagtaaa actgccctgc
    50641 agttcttggc agaaatcaag caaacacgca agggaaccat tacccaaaca gaaagagaac
    50701 tcttgcaaca gatggctggc ttgggcttgc tggacgaagt catcaatatc attcttttat
    50761 tgacctttaa taaggtggat tcggcaaata tcaatgagaa atatgccatg aaggtagcca
    50821 atgactatgc ctatcaaaag atacattcgg cagaagaggc agtcttgcgc atccgtgagc
    50881 gtgggcagaa gaatcaggct caaaaaagca gtacccctag tcctgccaag tccaatgtac
    50941 ccaagtggag caatccagat tataaaaatg aaaccagcga ggaaactcgt ctggaactag
    51001 aacgtaagaa acaagaacta ttagctcgat tagaaaaagg aggagattag atggaaagtg
    51061 tcggagacgt actcaagcgt caacctagcc gttttcatta tcaagatttg gtccagaaaa
    51121 tcatgaagga ccctgatgtt gcggccttta tccagcaaga atccttgacc ccagaggaat
    51181 tgaatcgcag tatctccaag tttaatcagt acatcaccga gcgcgacaag tttctccgtg
    51241 gtgatacgga ttatattgcc aaaggctaca agccgatttt ggttatgaat catggctatg
    51301 cggatgtttc ttatgaagaa actcctgagc taatcgcagc ggaaaaagaa gcggctatta
    51361 agaaccgtct caagttaatc aatctgccag ccagtctcaa gcaagctagt ttggctcaag
    51421 tagacttgga tgatttgggg cgcttaccag tttttgaaaa gttattagca ttcgtggagc
    51481 aatatccagc tattcgaaaa ggtctttact tgtatggaga ctttggtgtg ggtaaaagtt
    51541 tcatggtggc tgccttagct catgatttat cagaaaaacg tggtgtttcc tccactcttc
    51601 tccactatcc tagctttgtc attgatgtca aaaatgctat cggtgatggt aatgtcaaga
    51661 ccttggtgga tgagattaag ctttctgaag tcctgatttt agatgatatt ggtgccgagc
    51721 aatcaacagc ttgggtgcgt gatgaaatcc tgcaggtcat tctccaatat cggatgcagg
    51781 aaaatttacc gacctttttc acctccaact tcaactttga agaattggag ctgcatttcg
    51841 ctaaagggaa gcatggaaat gacgaaacct gggaagccag acgcgtcatg gaacgcatcc
    51901 gttatttggc tgaggagact cgtttagaag gagtaaaccg tcgatgacag aaaccattaa
    51961 attgatgaag gctcatactt cagtgcgcag gtttaaagag caagaaattc cccaagtaga
    52021 cttaaatgag attttgacag cagcccagat ggcatcatct tggaagaatt tccaatccta
    52081 ctctgtgatt gtggtacgaa gtcaagagaa gaaagatgcc ttgtatgaat tggtacctca
    52141 agaagccatt cgccagtctg ctgttttcct tctctttgtc ggagatttga accgagcaga
    52201 aaagggagcc cgacttcata ccgacacctt ccaaccccaa ggtgtggaag gtctcttgat
    52261 tagttcggtc gatgcagctc ttgctggaca aaacgccttg ttggcagctg aaagcttggg
    52321 ctatggtggt gtgattatcg gtttggttcg atacaagtct gaagaagtgg cagagctctt
    52381 taacctacct gactacacct attctgtctt tgggatggca ctgggtgtgc caaatcaaca
    52441 tcatgatatg aaaccgagac tgccactaga gaatgttgtc tttgaggaag aataccaaga
    52501 acagtcaact gaggcaatcc aagcttatga ccgtgttcag gctgactatg ctggggcgcg
    52561 tgcgaccaca agctggagtc agcgcctagc agaacagttt ggtcaagctg aaccaagctc
    52621 aactagaaaa aatcttgaac agaagaaatt attgtagaaa gtgagaaatt atggccctac
    52681 caactattgc cattgtagga cgtcccaatg ttgggaaatc aaccctattt aatcggatcg
    52741 ctggtgagcg aatctccatt gtagaagatg tcgaaggagt gacacgtgac cgtatttatg
    52801 caacgggtga gtggctcaat cgttctttta gcatgattga tacaggagga attgatgatg
    52861 tcgatgctcc tttcatggaa caaatcaagc accaggcaga aattgccatg gaagaagcag
    52921 atgttatcgt ctttgtcgtg tccggtaagg aaggaattac cgatgcagac gaatacgtag
    52981 cccgtaagct ttataagacc cacaaaccag ttatcctcgc agttaacaag gtggacaacc
    53041 ctgagatgcg aaatgatatc tatgatttct atgccctcgg tttgggtgaa ccactgccta
    53101 tctcatctgt ccatggtatc ggtacagggg atgtactaga tgcgattgtg gaaaaccttc
    53161 caaatgaata tgaagaagaa aatccagatg tcattaagtt tagcttgatt ggtcgtccta
    53221 acgttggaaa atcaagcttg atcaatgcta tcttgggaga agaccgtgtt attgctagtc
    53281 ctgttgctgg aacaactcgt gatgccattg atacccactt tacagataca gatggtcaag
    53341 agtttaccat gattgatacg gctggtatgc gtaagtctgg taaggtttat gaaaatactg
    53401 agaaatactc tgttatgcgt gccatgcgtg ctattgaccg ttcagatgtg gtcttgatgg
    53461 tcatcaatgc ggaagaaggc attcgtgagt acgacaagcg tatcgcagga tttgcccatg
    53521 aagctggtaa agggatgatt atcgtggtca acaagtggga tacgcttgaa aaagataacc
    53581 acactatgaa aaactgggaa gaagatatcc atgagcagtt ccaatacctg ccttacgcac
    53641 cgattatctt tgtatcagct ttaaccaagc aacgtctcca caaacttcct gagatgatta
    53701 agcaaatcag cgaaagtcaa aatacacgta ttccatcagc tgtcttgaac gatgtcatca
    53761 tggatgccat tgccatcaac ccaacaccga cagacaaagg aaaacgtctc aagattttct
    53821 atgcgaccca agtggcaacc aaaccaccaa cctttgtcat ctttgtcaat gaagaagaac
    53881 tcatgcactt ttcttacctg cgtttcttgg aaaatcaaat ccgcaaggcc tttgtttttg
    53941 agggaacacc gattcatctc atcgcaagaa aacgcaaata aaaaagtaga atctggaatg
    54001 acagttccgg atttttttga tataataaaa taatagaaaa cgctatcaaa agaaggaggg
    54061 tgatgtcggt gatggaacat ttgtttaaat tcttactttt agcaccgtac ttttattttg
    54121 ataactggat tgagaaggcc aacagaaata gtaagttttt tccaattttt tattattttt
    54181 actggtttta catccccttc tattctcttt ttagccttgc ttggacagtt gtttcagttc
    54241 tgtttttcaa taccgtcttg agaaatgtga cagatatcaa gttatggggc atttggtttc
    54301 tttttattct gctagctatt ggtatgaatt ggttaactta ttcctgtttc aaagaaatgt
    54361 ttcgcttgag acaggaacta gggaagtcta agggtggaag gcattgattt atatcggttt
    54421 ctatttgtag gaggtggctt atggtacctc taaaatcatt tattacacgc tattccaagg
    54481 tttatattgg taataacatt taatagaacg aaactaaaga aaacaattta aaaaaggagg
    54541 cttgtgatgg aacacttgtt taaaatgata atcttatcac cctgttttta ctttttcagc
    54601 tggattgaca aggataatag agaaagtaaa tttttcccaa ttttttacta tttttactgg
    54661 atttacatca ccctctatgc tctttttagc cttgcttaga cagttttttc agttctgttt
    54721 ttcaatatcg tcttgagaaa tttgacagat atcaagttat ggggtatttg gctattatta
    54781 ctacttatcg cttttgctag tgactggtta gactatatct gtttcaaaaa aatgcttgac
    54841 ttgagacggg aactagggaa gtctaaaggc ggaaggcatt gatttatact cttcgaaaat
    54901 ctcttcaaac cacgtcaacg tcgccttgga ttatatatgt aactgacttc gtcagtctta
    54961 tctacaacct caaagcagtg ctttgagcaa cttgcggcta gtttcctagt ttgctctttg
    55021 attttcattg agtattatat tactttctat ttgtaggagg tggcttatga agattcctct
    55081 cttaactttt gcaaggcata aatttgttta tgtcttgctt actttgcttt ttcttacttt
    55141 ggtttatcgt gatgttttga tgacttattt cttttttgat attcatgcgc ccgatctagc
    55201 taaattcgat ggacaagcaa ttaaaaatga cttattaaaa tcagcattag attttcgtat
    55261 tctccagttc aatctaggtt tttatcaatc atttattatt ccaatcacca ttgttttgct
    55321 aggttttcaa tatattgagc tgaaaaataa agttttacga ttgagtattg gaagagaagt
    55381 gagctatcaa gggctaaaaa gaaagttgac tttgcaagtt gcaagtatcc cttgtttaat
    55441 atatttagtg actgtgctga taattgcaat tttaactcat ttctttggga ctttttctcc
    55501 tcttggatgg aattctctat tttctgacgg gagtagttta caaaggctcc tagatggaga
    55561 gataacaagc tatttgttct ttacttgtgt cctactaatc ggtattttca tcaatgcagt
    55621 ctattttttt aaaatagttg attatttagg aaatgtgact cgttcggcaa tcgcctattt
    55681 gatgtttctt tggcttggtt ctatgttact ctatagtgcc ttgccttact atatggttcc
    55741 tatgacgagt ttgatgcaag ctagctatgg ggatgtaagt ttgatgaaac tctttactcc
    55801 ttatatcctt tatattgtcc cttatatggt tcttgaaaaa tatgaagata atgtttaaga
    55861 attttaacaa tattttgcta aagagaaaga ttgttttact acttcgtata gttctgatga
    55921 tgattttgat aaactatcta ttgtcaacag cggttcaaaa gcaggatgct gttatctttt
    55981 tcaagagaga attgatttca atcttttcct ataatgacta ttctgaagcg aatttagaaa
    56041 tccccaaact cttgttaaac ctttcgcttt tcatggtagg atggctctct gtcattttac
    56101 ttgaaagtga tttggcagat cattaccatc acttgattcg ctatcaatca agctcctttt
    56161 tagattatac aaggaaacga ttggttgtca tttctaaatt ttttactcaa gatttgtttg
    56221 tctggtttct tggtttactt cctataggaa ttcatttcaa aacagtcgca cttttctttt
    56281 tacttgctca gttaatgatg ttgtacttac tactgtctta tctgatagca ctgattagtg
    56341 cgggcgctgg tttttccttt tttctctatt ttttagcatt tgtgggacaa gaatggatga
    56401 tggatcatat tgtaacagtg tatttagtac ttttaagttt attagttatg ttgattgtta
    56461 gtcgcttgga agagaaattt aagaaaggat aaacgatgag acttgaaatt ataaatggac
    56521 agaaaattta tgggaaaaga cctattttaa atcagttgaa tttggtgttt caatcaggaa
    56581 aaatttatgg acttaaaggt gataatggat ctggcaagac ggttctttta aagatacttg
    56641 ctggttatat taagcttgac aaaggaaaag ttcttcaaga cgggaaagtc tacgggataa
    56701 aaaatcatta tattcaggat gcaggaattt taattgaaaa agtcgagttt ttatctcatt
    56761 tatccctgag agaaaatttg gaactgttaa ggtatttttc atctaaagtt acggaaaaaa
    56821 gaattgccta ttggattcaa tactatgatt tacaggaatt tgaagacgtt gaataccgtc
    56881 atttatcctt aggaacaaag caaaaaatgg ccttgattca agcctttatt tcctctcctt
    56941 ctatactctt tctcgatgaa cctatgaatg ctttggatga gaagagtgtg aggttaacca
    57001 aacaggtcat tttatcttac ctgaaaaaag aaaatggtct ggttatcctg acgtcgcaca
    57061 tatcggaaga tatttcagac ctttgtacag atgtattagt tgtcgaaaat ggacatatac
    57121 aatatgtaaa ggatatacaa tcctaggaga tggcttatgg cacatctaaa atcatttatt
    57181 acacgctatt ccaaggttta tattggttta gttctgctga tctggctgac tttcttcttt
    57241 ttcccttggg atagagcgat tctgggggta aggattgaca tcttcatcat acagaaagtc
    57301 ttgctagttt ttggaattct gtccattctc atggccttgc tgtccaagaa agtcagtctc
    57361 tttgtttttg gactgatttg ctgtctttct ctttggatta acttatttat cacatttgcc
    57421 attttgccga tttttggcaa ttaaacagtc ataaaagtcg gagaggttag cttgaaaact
    57481 aacctctttt tccttttcaa aatggggatt cttccttgaa aataatcagt aattgtgcta
    57541 aaattaaagg aacattctaa aatattcgga atttaaagta aggaaaaaca tggctaatat
    57601 tttaaaaaca attatcgaaa atgataaagg agaaatccgt cgtctggaaa agatggctga
    57661 caaggttttc aaatacgaag accaaatggc tgctttgact gacgaccaac taaaagcaaa
    57721 aacagttgaa tttaaggaac gttatcaaaa tggagaatca ctggattcat tgctttacga
    57781 agcatttgcg gttgtccgtg aaggtgccaa acgtgtccta ggtctcttcc cttataaggt
    57841 tcaggtcatg ggggggattg ttcttcacca tggtgacgtg ccagagatgc gtacagggga
    57901 agggaaaacc ttgactgcga ccatgccggt atacctcaat gccctttcag gtaaaggggt
    57961 tcacgtagtt acggttaatg aatacctgtc agaacgtgac gcgactgaga tgggtgaatt
    58021 gtactcttgg cttggtttgt cagtagggat taacttggct accaaatctc caatggagaa
    58081 aaaagaagcc tatgagtgtg atattactta ctcaactaac tcagaaatcg gatttgacta
    58141 ccttcgtgac aacatggtcg ttcgcgctga aaacatggta caacgtccgc ttaactatgc
    58201 cttggtcgat gaggttgact ctatcttgat tgacgaggct cgtacacctt tgattgtatc
    58261 aggtgccaat gcggttgaaa ccagtcagtt gtatcacatg gcagaccact atgtaaaatc
    58321 tttgaacaaa gatgactaca tcatcgatgt gcagtctaag actattggtt tgtctgattc
    58381 agggattgac agggctgaaa gctacttcaa acttgaaaac ctctatgaca ttgaaaacgt
    58441 ggctttgact cactttatcg ataacgccct tcgtgccaac tacatcatgc ttctcgatat
    58501 tgactatgtg gtgagcgaag agcaagaaat cttgattgtc gaccaattta caggtcgtac
    58561 catggaaggt cgtcgttatt ctgatggatt gcaccaagct attgaagcca aagaaggtgt
    58621 gccaatccag gatgaaacca agacatctgc ctcaatcacg taccaaaacc tcttccgtat
    58681 gtacaagaaa ttgtctggta tgacgggtac aggtaagact gaggaagaag aattccgtga
    58741 aatctacaac attcgtgtta ttccaatccc aacaaaccgt cctgttcaac gtattgacca
    58801 ctcagacctt ctttatgcaa gtattgaatc taagtttaaa gcggttgtcg aagacgttaa
    58861 ggctcgttac caaaagggtc aacctgtctt ggttggtaca gtagcggttg aaactagtga
    58921 ctacatttct aagaaattgg tcgcagctgg tgttcctcac gaagtcttga atgccaaaaa
    58981 ccactataga gaagcccaaa tcatcatgaa tgctggtcaa cgtggtgccg ttaccatcgc
    59041 aaccaacatg gcgggtcgtg gtaccgacat caagcttggt gaaggtgttc gtgaacttgg
    59101 aggactttgt gttattggta cagaacgtca tgaaagtcgt cgtatcgata accagcttcg
    59161 tggacgttca ggtcgtcaag gagatccagg tgagtcacaa ttctacctat ctcttgaaga
    59221 tgatttgatg aaacgttttg gttctgaacg cttgaaggga atctttgaac gcttgaacat
    59281 gtctgaagag gccattgagt ctcgcatgtt gacgcgtcag gttgaagcag ctcagaaacg
    59341 tgtcgaagga aataactacg atacccgtaa acaagtcctt caatacgatg atgtcatgcg
    59401 tgaacaacgt gagattatct atgctcaacg ttacgatgtc atcactgcag atcgtgactt
    59461 ggcacctgaa attcaggcta tgatcaaacg cacgattgaa cgtgtcgttg atggtcatgc
    59521 gcgtgccaaa caagatgaaa aactagaggc aatcttgaac tttgctaagt acaacttgct
    59581 tcctgaagat tctattacga tggaagactt gtcaggcttg tctgataagg ccatcaagga
    59641 agagcttttc caacgtgcct tgaaggttta cgatagtcag gtttcaaaac tacgcgatga
    59701 agaagcagtt aaagaattcc aaaaagtttt gattctacga gtggtggata acaagtggac
    59761 agatcatatc gatgcccttg atcaattgcg taacgcggtt ggacttcgtg gctatgctca
    59821 gaacaaccct gttgttgagt atcaggcaga aggtttccgt atgtttaatg atatgattgg
    59881 ttcgattgag tttgatgtga cacgcttgat gatgaaagca caaattcatg aacaagaaag
    59941 accacaggca gaacgtcata tcagtacaac agcgactcgc aatatcgctg ctcaccaagc
    60001 aagtatgcca gaagatttgg atttgagcca gattggacgc aatgaacttt gcccatgtgg
    60061 ttctggtaag aaatttaaaa actgtcacgg taaaagacaa taaaatgaga tagtttagag
    60121 gcggatatct tgtgaaaagt aaatttttac tgggtatccg tttgctttat aaggagatga
    60181 gttatggtat ttacagcaaa aagctctaaa ataaatatag aagaagttcg tgccttgtca
    60241 aaattagaag gtcaggcttt ggagaggaaa tcacagcgag atcaagagct agaagccatt
    60301 atacgtggag aagaccagcg aattctcttg gtaatcgggc catgctcatc tgacaacgaa
    60361 gaagctgtcc ttgaatacgc taggcgtttg gcagtcctac aagaagaagt ggcagatcgt
    60421 atctttatgg ttatgcgtgt ttatactgcc aaaccccgta ccaacggaga tggctataag
    60481 ggcttgattc accagcctaa cgcgacagaa gcgcctagtc ttatcaatgg aatcaaagcc
    60541 gttcgccatc ttcactatcg tgtcatcaca gaaacaggga tgacaactgc tgatgaaatg
    60601 ctttatcctg aaaaccttcc gcttgtagat gatttgattt cttacatggc agttggtgcc
    60661 cgttcagttg aagaccagca acaccgcttt gtggcaagtg gggcaggatt ttctactggt
    60721 tttaaaaatc caacctctgg aaatctcaat gtcatgttta atgggattta tgctgctcaa
    60781 aacaaacaaa gtttcctttt cttaggaaaa gaagtagaaa caactgggaa cccgctttca
    60841 cacgctattc ttcgtggtgc tcttaatgag tatggaaaaa atattcccaa ctactattat
    60901 gacaatttaa ttgataccat tgcccagtat gagaaaatgg gcttggaaaa tccttttatc
    60961 atcattgata ccaatcatga caattctggt aagcagtata ttgaacagat ccgaattgtc
    61021 cgccagacct tgattaaccg tgcttggaat gaaaaaatta agcagttcgt tcgtggtttt
    61081 atgattgagt cttatctgga agatggtcga caaaatgagc cagaagtatt tggcaagtct
    61141 atcacagacc cttgcctggg ttgggataac acagaagctc ttgtcagaga aatttacaaa
    61201 acgttaggag aataagatgg catttattga aaaaggtcaa gaaatcgata tggaagtcat
    61261 caaggctgaa acccaattgt ctgcggaagc cttgagactc aaggaaagcc gtgacaggga
    61321 attggcagat attatttcag gggaagatga ccgtattctc ttggtgattg gtccttgctc
    61381 ttctgataat gaagaggcgg tcttggaata tgctcgccgt ttatccgcct tgcaaaagaa
    61441 ggtagcggac aagattttca tggtcatgcg cgtgtatact gctaagcctc gtaccaatgg
    61501 agacggctat aaaggattgg ttcaccagcc agatacttct aaggctccaa gcctgattaa
    61561 cggcttgcag gctgtgcgcc agttgcacta ccgcgtgatt acagagactg gtttgacaac
    61621 ggcagatgag atgctttatc cgtcaaatct gatcttggtg gatgacttgg tcagctacca
    61681 tgccgttgga gctcgttctg tggaagacca agagcaccgc tttgtggctt ctgggattga
    61741 tgcaccagta gggatgaaaa atccaacctc aggaaatttg ggtgttatgt ttaacgccat
    61801 ctatgctgct caaaacaagc aaaccttcct ttatcatggg caggaagttg agacatcagg
    61861 taatcctttg gcccatgtta tcctccgtgg agcagtcaac gagtatggta attatatgcc
    61921 gaattactac tatgaaaacc tactccaagc cattgaacgc tatgaaacca tgggacttga
    61981 aaatcctttt atcctcattg acaccaacca tgataactca ggcaagcaat atatggagca
    62041 gattcgaatt gttcgccaga ccttgcagaa tcgtgattgg aatgagaaaa ttaaaaagac
    62101 ggttcgagga tttatgattg aatcttacct agcagatggt cgtcaaaacc aaccagaggt
    62161 ctttggttgc tctattactg acccttgcct aggttgggaa aatacagagg ccttggtaga
    62221 agagatttat gttaccttga caaaataagt gaaaaggatg gagttgggga atctcaactc
    62281 cttttgatga gaatgatagt tggacacgga attgacatcg aagaattggc ttcgatagaa
    62341 agcgcagtta cacgacatga aggatttgct aagcgtgtac tgaccgctca ggaaatggag
    62401 cgcttcacca gtctcaaagg acgcaggcaa atagaatatt tagctggtcg ctggtcggct
    62461 aaggaggcct tttccaaggc tatgggaacg ggcattagca agctcggttt tcaggatttg
    62521 gaagtcttga acaatgaacg tggggcgcct tattttagtc aggcaccatt ttcaggaaag
    62581 atttggctgt ctatcagcca caccgatcag tttgtgacag ccagtgtcat tttggaggaa
    62641 aatcatgaaa gctagtccac atagaccaac caaggttctg attcatctgg gagctattcg
    62701 acaaaatatt cagcaaatgg gggctcatat ccctcaagga acgctcaagt gggctgtggt
    62761 caaggccaat gcttatggtc atggagctgt tgccgttgcc aaggaaattc aagatgatgt
    62821 tgatggcttt tgcgtttcca atatcgatga agccattgaa ctcagacaag ctggactcag
    62881 caagccaatc ctcattttag gagtttctga aatcgaagct gttgctctag ctaaagaata
    62941 tgacttcacc ttgacagtgg ctggactgga gtggattcaa gcactcttag ataaggaagt
    63001 ggacctaact ggattgacag tccacctcaa gattgattca gggatgggac ggattggttt
    63061 tagagaggcc agtgaggttg agcaggctca agatttgctc caacaacacg gtgtttgtgt
    63121 tgaaggaatc tttacccact ttgctactgc tgatgaggaa tcagatgact attttaatgc
    63181 ccagttagaa cggtttaaaa ctattttagc tagtatgaag gaagttccag agctggttca
    63241 tgctagcaat tctgcaacga ctctttggca tgtagagact attttcaatg cggttcgtat
    63301 gggagatgcc atgtatggtc tcaatccaag tggagcggtc ttggatttgc cttatgattt
    63361 gataccggcc ttgaccttgg agtctgctct ggttcatgtc aagacagttc cagctggagc
    63421 ttgcatgggt tatggagcaa cttatcaagc ggatagcgag caagtcatcg cgaccgtgcc
    63481 aatcgggtat gcagatggat ggacaagaga catgcagaat ttctctgtct tggtagatgg
    63541 ccaagcttgc ccaattgtcg gcagggtttc gatggaccaa atcactattc gattacctaa
    63601 gccttaccca ctcggaacca aggtaacctt gattggctcc aatggggata aggaaatcac
    63661 tgcaactcag gtagcgacct accgcgtaac cattaactat gaggtggttt gcctcctcag
    63721 cgaccgtatt ccgagagaat attattagaa aagaaaggag tggagcatga atctacatca
    63781 acccttgcat gtcttacctg gtgtgggact aaagtcagca gaaaaatacg ccaaactagg
    63841 aattgaaaac ttgcaagatc tcttgctcta ctttcctttc cgttatgaag acttcaaaac
    63901 caagcaggtg ctggagctgg aagacggtga gaaggcagtt ctttctggtc aggtagtgac
    63961 tcctgctagt gtccagtatt atggtttcaa gcgcaatcgc ctgcgtttta gtctcaagca
    64021 gggagaggtc gtttttgcgg tgaatttctt taaccagccc tatctggctg ataaaataga
    64081 gttgggagca acccttgctg tctttggaaa atgggaccgc gctaaggcta gtctgactgg
    64141 gatgaaggtt ctggctcagg tagaagatga cctccagcct gtctatcgtc tggctcaggg
    64201 aatcagtcag gccagtctgg ttaaggtcat caagacggct tttgatcagg gactggacct
    64261 cttgatagaa gaaaatctgc cccagtcttt actagacaaa tacaaactca tgtcccgttg
    64321 tcaggcagtc cgagctatgc attttccaaa ggatttggca gaatacaagc aggctcttcg
    64381 ccgtatcaag tttgaggaac tcttttattt ccaaatgcag ttgcagacgc tcaagtctga
    64441 aaatagagtt cagggaagtg gtctggttct gaattggtct caggaaaaag tgacagcagt
    64501 taaagcaagt cttccttttg ccctgaccca agctcaggaa aagagtttgc aggaaatttt
    64561 aattgatatg aagtccgacc accacatgaa tcgtctccta caaggagatg tggggagcgg
    64621 aaaaacggta gtcgctggct tggccatgtt tgcggcagtg acagcaggtt atcaggctgc
    64681 cctaatggta ccaacagaaa tcctcgcaga gcaacacttt gagagtttac agaacctttt
    64741 tcccaatttg aaactggctc tcttgacagg ttccttgaaa gctgcagaaa agagagaagt
    64801 cttggagacc attgccaagg gtgaggctga tttgattatc ggaactcacg ctctgataca
    64861 agatggggtg gagtatgctc gtcttggttt gattattatc gatgagcagc accgttttgg
    64921 tgtggggcaa aggcgtattt tacgggaaaa aggcgacaat ccagatgtcc tcatgatgac
    64981 ggcgactccc attccacgga cgcttgccat cacagccttt ggagatatgg atgtttccat
    65041 tatcgaccag atgccagcag gtcggaaacc tattgtgacg cgctggatca aacatgagca
    65101 actacctcag gtcttgactt ggttagaggg ggaaattcaa aaaggttccc aagcctatgt
    65161 catctctcct ttgattgaag aatcagaagc tctagatttg aaaaatgcca ttgccttatc
    65221 agaagagctg acggctcatt ttgcaggtaa ggcagaagtg gctcttctac atggtaagat
    65281 gaagagtgac gaaaaagacc agatcatgca ggatttcaag gagagaaaaa cagatattct
    65341 ggtttcaaca acggttatcg aggttggggt caatgttcca aatgcgactg tcatgatcat
    65401 catggatgcc gatcgcttcg ggcttagtca gcttcaccag ctcagaggtc gtgtcggtcg
    65461 gggggacaag cagtcctacg ctgttctcgt tgccaatccc aagacggatt ctgggaaaga
    65521 ccgcatgcgc atcatgacag aaacgaccaa tggatttgtc cttgcggagg aagatttgaa
    65581 aatgcgtggt tctggtgaga tttttggaac cagacagtca ggacttccag agttccaagt
    65641 ggctgatatt atcgaagatt ttccgatttt agaagaagct agaaaagttg ttagttacat
    65701 tagttctatt gaaggctggc aagaggatcc agagtggcgc atgattgcct ttcatctgga
    65761 aaagaaagaa catctggatt aagctttctc taaggaaaac ttaagctagc tttcaggttt
    65821 ggcccttata ctagagtcat caaaaagaaa cgaggactct catatgacag taacgattaa
    65881 agtaaattac ccaagcactt ttcaaaagaa agaagcaaca gattaagatt gagcagaaga
    65941 aaaagggcgg aaatgctctt ttttcgtttc taaaactact ttcagtcaat aggcttgaag
    66001 gaagaaaagc taaattcact ttctatttac ccttctttct tgcattgctt tcttagatgt
    66061 gctacagtgg tgctagcgat tacaaaacaa aaggagcatg ctatgaaaaa tccagctttg
    66121 ttagaagaaa tgaagatcta tctaggaagg gacgaggttc cagaagacgt tgatgctttc
    66181 tgggatgagg aagtgaaaaa agtttccacg cttccagcct accagttgga ggaaataaat
    66241 ttccacattt ctcaagtcaa gtgctatgag ctaacctttg aaggaagcaa gcaaggcaag
    66301 gtctatgcac gagttgttct tccaaagagt gaggagaagg ttccgttaat cttccatttc
    66361 catggttata tgggacgtgg ttgggattgg gccgacatgc tggctttcac cgtagctggt
    66421 tacggtgttg tttccatgga tgttcgaggc cagtcgggct attcacaaga cggtttgcgc
    66481 tctcctcttg gaaataccgt taagggacat atcatccgtg gtgctgtgga aggtcgggac
    66541 cacctctttt ataaggatgt ttatctggac atttaccagt tggttgaaat tattgctagt
    66601 ctgcctcagg tagatgagaa gcgactttcc agctatggtg cctcgcaagg aggggctcta
    66661 gctttggttg cagcagcgct caatcctcga attcagaaac cagttgccat ctatcccttc
    66721 ttgtcagact tcagacgagt gcttgagatt ggtaatacta gcgaagccta tgacgaactt
    66781 tttagatatt tcaaatttta cgaccccttc catgaaactg aggaggagat catggcgatc
    66841 cttgcccatc gtatcaaggg tgaggttaag atgattacgg gtttggatga cgatgtttgc
    66901 tatcccatta cccagtttgc gatttacaat cgtttgacct gcgataaggc ttatcgcatc
    66961 atgcctgagt atgcccatga agccatgaat gtttttgtca atgaccaggt ttataactgg
    67021 ctctgtggga gtgagattcc tttcaaatat ctaaaataag gagtcgactc taggcacaaa
    67081 atcttaaaaa tcacaaacac gcatagtatc aggggattaa gaagacttga tactatgcgt
    67141 tttatcatgg aaatatagta aaatgaaaca agaacaggat aaatcgatca ggacagtcaa
    67201 atcgatttct aacaatgttt tagaagtaga tgtgtactat tctagtttca atatattata
    67261 tttatagaat tttttgttgc tagatttgtc aaattgctta aaataatttt tttcagaaag
    67321 caaaagccga tacctatcga gtagggtagt tcttgctatc gtcaggcttg tctgtaggtg
    67381 ttaatacttt tcaaaaatct cttcaaacca cgtcagcttc gtcttgccgt aggtatggtt
    67441 actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga cttcgtcagt
    67501 tctatctgcc acctcaaaac ggtgttttga gctgactttg tcagtcttat ctacaacctc
    67561 aaaacagtgt tttgagcatc atgcggctag cttcctagct tggtctttga ttttcattga
    67621 gtgtaaaaaa acagatgagt ttctgttttc tttttatgaa ctataaatgt tcagctgaaa
    67681 ctactttcaa ggacattatt atataaaaga gttttttgaa actaaaatct actatactac
    67741 actatattga aagcgtttta aaaatgaggt ataataaatt tactaacact tataaaaagt
    67801 gatagaatct atctttatgt atatttaaag atagattgct gtaaaaatag tagtagctat
    67861 gcgaaataac agatagagag aagggattga agcttagaaa aggggaataa tatgatattt
    67921 aaggcattca agacaaaaaa gcagagaaaa agacaagttg aactactttt gacagttttt
    67981 ttcgacagtt ttctgattga tttatttctt cacttatttg ggattgtccc ctttaagctg
    68041 gataagattc tgattgtgag cttgattata tttcccatta tttctacaag tatttatgct
    68101 tatgaaaagc tatttgaaaa agtgttcgat aaggattgag caggaagtat ggtgtaaata
    68161 gcataagctg atgtccatca tttgcttata aagagatatt ttagtttaat tgcagcggtg
    68221 tcctggtaga taaactagat tggcaggagt ctgattggag aaagtaaagg gactccaaaa
    68281 tgcaactgtt catgtggagt tcaaaccggc tgctgatggt cctagttttt acaatctctt
    68341 ttctgcttcc agtacaacta aagtaaatga atactttaca atggcaatca ataatgggac
    68401 agctttgata gagggacgtg gagctgatgg tagccaattt tatggaagtt atacagatgc
    68461 gcctttgaag attagaccag gcaagtataa ttcggttact tttactgttg aaagaccaag
    68521 aaaggatagt ccaaatggtc aggttcgtct ttatgtgaat ggtgtattat ctcgtacgaa
    68581 taaaaagtca gggaaattcc tggcagatat gccagatgta gataaactcc agttaggtgc
    68641 aactaataga gcaggagaac tgaagtggag ctcagatctt tctattcgta atctgactgt
    68701 atacaatcgt gctctaactc cagaggaagt caaaaaacgt agccagttgt ttgatgtgat
    68761 agatattgag cctttacttg ctgaaggggc agtcttgaca gagaagcaag agttgtttat
    68821 gagtgatgtc aatggtaagc caaatagtga gggaattaag agttatcgga ttccagcttt
    68881 gctacgtacg gataaaggaa cattactggc aggggcagat cagcgtcgtc tccaccattc
    68941 tgattgggga gatgttgcta tggtcgttag gagaagtgag gatgggggaa ctacttggca
    69001 gccaacctta accttgacca acctgcgaga caatccagaa gcaaaagatc cgcaggcatc
    69061 atctccactt aatatcgata tggtcttggt tcaagatcct accacaaaga gaattttttc
    69121 aatctacgat atgtttccag agggtcgagc tgtctttgga atgccaaaca aacctcaaaa
    69181 agcttatcaa caagttggag acaagcacta tcaattacta tataaacaag gggaaaatca
    69241 agcatatact gttcgagaaa acgaagaagt atatgatgca aataatcaaa aaacagatta
    69301 tcgcgttgta gtggatccaa aagaagaagc ctatagagat aagggcgacc tctataaagg
    69361 agaagagctt cttgggaata tctactttgc tcaatctgct aaaactccat ttcgtgtagc
    69421 ctatacgagc tatttgtggc tttcctatag tgatgatgat gggaaagctt ggtcgcaacc
    69481 aagagatatt acaccatcaa ttcgccaaga ttggatgaaa tttttaggaa caggtccagg
    69541 tacaggaatt gtgcttagaa caggagagca caagggacgt atcctagttc ccacttatac
    69601 caccaatgct atctcccatc taagcggctc ccagtcttca cgtttgattt attcagatga
    69661 tcatggagaa acatggcagg ctggagctgc tgttaatgat gataggacgg taggcagaag
    69721 gaaaattcat tcctcaacta tgaataatag gaatgcccaa aatactgagt cagttgctgt
    69781 gcagttaaat aatggtgatg tgaaactctt tatgagaggg ttaacgggtg atttacaggt
    69841 tgccacaagt aaagatggtg ggcaaacttg ggacaaggaa atcaagagat ataatcaggt
    69901 taaagatgtt tatgtccaaa tggctgctat tcacaccatg cacgaaggaa aagaatatat
    69961 cattttaacc aattcaggag gacctaaacg gacgaatgga atggctcatt tggctcgtgt
    70021 agaggacaac ggagacttga cttgggttac atcatagacc aattcaaaaa ggagagtttg
    70081 cctataattc gcttcaagaa ttaggaaatg gggagtatgg tatcttgtat gaacatactg
    70141 aaaaaggaca aaatgactat accctatcat ttagaaaatt taattgggac tttttaacaa
    70201 aggagccggt atatccaacg agtgtaacta tcagggacgt tcgtaaattg gaaacagaag
    70261 aagaggatgc agaacaaggc atcttagcta tgcaatttga ttctgaggta ctagtgaatg
    70321 ctattccgac tttgacttta gcgaatggac acaaagctac cttcttgacc caagcagatc
    70381 aaaaaactct acttttcacc tttaataaag aagatgcagg tcaagaaatt acaggtctaa
    70441 tggccggtag aattgacagt atgcatgatt taccagttac actagctggt agtagaattc
    70501 ctgaagatgc gaaagaaaat cctgtcgaga ccatgaatac agtaagagaa aatgtatctg
    70561 aggagatgac agaaaggaag tcagagaagg ataaattatc tttggagtct tcagatagaa
    70621 tggtagcaaa ctctcctctt acttcttttg ctcctcgtta cctccaatct tatgtaggag
    70681 atgttattaa aactgagact aaagttccaa taacgactgg ttggaagcaa gaaaatggtg
    70741 cgtggtattt ttatacatct gctggtgaag tggtgaaagg ctggcatcag gaagcggata
    70801 aatggtacta cttgagttct actggtgcga tggcaactgg ttgggtcaga gatggtaatc
    70861 aatggtatta tttgagtgag agtggagcaa tgtctactgg ctgggttgaa tccagtggtg
    70921 tgtggtacta tctccattct aacggttcaa tggcgactgg ttggataaaa gatggagacc
    70981 attggtacta tcaggaatca tctggtgcaa tgagggtaaa tcaatggttc caagttggag
    71041 acaaatggta ctatgtcaat gaaagcggaa gattagctgt taataccata gtggatggtt
    71101 atcaagttaa ctccaatgga gagtgggtca actactagag acttggatgt tgatgaataa
    71161 ctgagacacg ttttattcgt catagagatt aaaagtttat ttagatagtt ttcgtagaga
    71221 tttctactct aaggaaaaat caatttaaat gagcttctat tgccgggtaa atgacttgct
    71281 aatcgtaaat aaactgtata tttccgactt acttccgact ggatactact agtcgcaatt
    71341 taacagttcg ctttaagtgt taaaatgcat atagctagtt attggttata tgcgtttttg
    71401 ttcttgatta ttttatttct tgtcttggaa tataggtaaa attatagtaa aataaaattc
    71461 tgtaattcat gttggtagat atacaggaag aagagtgtat tgttgacaat atagcacata
    71521 gaatccaata tgtccttata ctcaaaaaat caaagagcaa attaggaagc tagccgtagc
    71581 ctgcccaaaa caccgttttg aggttgtaga tgaaactgac gaagtcagct caaaacaccg
    71641 ttttgaggtt gcagatagaa ctgacgaagt cagtaacata tacatacggc aagacgaaga
    71701 tgacatggtt tgaagagtat ggaacaatca taacttattt gaagatttta aaagattata
    71761 agctattata tctggataaa taagtattag aaactaaagt gaggaaaaga tgtttttata
    71821 tttaaaaggt ttaggtaaat atcgtaagtc aaaagcttac gggttggtgg gatgtctggc
    71881 attagtgagt atgattggat tagctgcacc agacttacca gttattggtg gtggagtcgt
    71941 tgctgctgat gttattcagg gtggtaacga tataaaagat gtgaacgttc atagtaaatc
    72001 tgcggaaggt gttgctatga cctataccac ttatgatagc ggaacaagtg gaaaacaaac
    72061 cgcatcaggt agcggtgtct ttgtagcgcc gaatgtgatg gtaacagtag ctcataacta
    72121 ctatgataaa aaccaagagg ataagtctgc ggtcttgcgt ggtggggcgt ctgctcgtag
    72181 ttatgttgtg atgaactcag agacggaaaa gcacaataaa gtacctactt ctggtgtatc
    72241 agaaactctt gaaaaagact ctattcattt gtatgatgag aaaaattttg ggaaagacta
    72301 tagcaacgac ttagcagtag tggtaactaa aaagactgta gaagctatga caggtggtga
    72361 agattcacca agagaattga gccataaaga ggtttctact ggtgataaaa tctctatggt
    72421 cggctatcct aatgactttt caactccgaa tttaagtgca gaaaacaaag cacgattgaa
    72481 agacggtaag gcttattcag ttacaacaac tgtaagtagt gtcaataaag agagtggtac
    72541 agtcacttat cattcctcag ctttaggagg tttttcaggt gctcctttgt ttaatgataa
    72601 gggagaggta gtcggtatcc accaacatgg gacaaatact ccaaacgctc aagaaagtga
    72661 gcgtattggt ggtggtaccc tctttacgga aaagcacaga gcttggattc gttctatgat
    72721 tgataaatat ggtataaagg gttggtatat agatggtgca aaccgttact actatgatga
    72781 aaatcacaga gccttaaaag atgtagagtc tgagattgac ggtgctttgt atcgttttga
    72841 tgaaaaaggc cgagctactt tactagaggg tgaagaaaaa ggtcgcgttc tacttcgagt
    72901 ggaagatact aaaggaactc ctttgatttc agataaggtt gttcaagaag gttctgttgg
    72961 aagtggtttg aattttcatt taagacaaaa tccaaacttc aaacagttaa tagcaacttc
    73021 tccaacagct aaagtggtat cctataacgg agtgccaatt aacaaattag caagtgatac
    73081 aagttggtct gatgaatatg tcagtaagtt agctttgggt gatacaatta taagagcggt
    73141 agtagattcg gtaactcctc catctacgtc ttcttcggat tttgcaagaa ctgaagttgg
    73201 taaggttgat ttgagtggta aatcgaactt acctgtgcct agtaaagagg tattacaagc
    73261 tccgaatggt tcagaaaact tctatgctac aacgcatatt caaacgccag atgggtcggg
    73321 gtcaggtact ttaattgcac caaatttggt gttaacagtc gctcataatt tcttaacagt
    73381 taaaggttct gaggtagtta cgaagtctgg tcgcaccaat acagtgtata aagctacttt
    73441 gccaagtggt cagcctgtga atttttccga tgatgatatt gtttattgga acaagaaaga
    73501 ctcagtattt ggatttaaaa atgacttagc tttggttcgt ttgaaagaaa agcttacagc
    73561 ggtatctcct gtagaggtgg tatctgagtc aacttcgatt actaaaggtg acaaagtttc
    73621 cgtttatggt tttcctgatg gtcgtttgtc tccagttttg gatagtgaag tagtagctac
    73681 tactgacttt ggttcaggta ttgaagggat tagctatggt ggtacaaaac ccggagcttc
    73741 tggtggtggt ctttataatg acaaaggttc tttaattgga gttcaccaaa atggtgttgt
    73801 aggaagccgc agtggtgggt tagtcttatc aaaagaacaa ttagattggg ttcgttccta
    73861 tattgagggt aaacccaaag cccctgttta tgtaacagat aatattttgg tggatgaaaa
    73921 agacaaggat aaacttccat caacttcaaa agaagaaaaa ccgaccacac caaaagtaga
    73981 gtcggataaa gataaaccaa atacacctct aaaaccgcaa gaaaagccga aaacagaggt
    74041 tataacgagt tatgagggtg atagtaccct tgaagttggg aaagagcgta cagaggaaac
    74101 tgagggcgaa aaagaaggtg tttcccttat ttatcgaacg gtgtataaag gtactaaatc
    74161 gaaaacagaa atgtcaccta ttgcctttga cacggtttac caaggagatg aaactaaaga
    74221 gcttggtttc cgttcagttt tagagggtaa agagggtcta gttactcgca ctacaagtta
    74281 ccaagtagat aagtacacag gagcggtatc ctccaagatt tctgaagaga aaatagcacc
    74341 tcaatctcaa gtcatcacat taggtattaa gaaaaatagc agcacaaaag aagttccaat
    74401 tacagaacgt tttgaagatt ccgcagaact agagaaaggt aaaactgagg ttatttctga
    74461 aggttctgta ggtaaagagg ttactacggt tacttataag gttttacctg atggaaaggt
    74521 tattgaaaat tctcgtacag ttgacgttac acccatgaga gagcgtgtag ttcgtaaggg
    74581 tgtgaaggaa gtggtatctc cagataaagt agagtctcta gttccaaaag atgcgccgat
    74641 tagagaagag cagcctgcgc ttagtgaggg attttcagag tcagatgctt tagtatcagg
    74701 agaaaaaata caaggagatc ttgggatact tatagtatct tcagaagaac tagtccctga
    74761 aagagtagaa gttccagatt ttgtgactaa agttacaggt ggagaaaaat tgacagtaga
    74821 agggcaccga aatgagagta aaataaagac tccatcaaaa caggaaagat catctcgccc
    74881 agaaaccact gctcaattca caacgaacgg gacaggttcg tcatcgttaa cagctgtttt
    74941 tggcggtaaa acggataaaa tattactttc tactgttgaa cattctgtta ttaaacataa
    75001 tcaacaaaga ggatggcata agataaataa tcagtggtat tttagaaatt ctgatgggaa
    75061 agaacggaca ggttggatga aagaaaatga tgcatggtat tattttgata cgaatggaac
    75121 catgcaaact ggttggctag aggatacaga cggtaattgg tattatctca atgataatgg
    75181 taggatggag ataggctggt tccaagattc aagtggcgcg tggtactact taggatcatc
    75241 tggtcgcatg gaatccaata catggattta ttataaagga aagtggtact atattgatgc
    75301 tttgggtaaa ctacttttca attcggtaac accagacggc tatagagtga acgagtatgg
    75361 ggaatggatc aactgaactt gctttatggc atattgacga gaaagctagg agtataaaaa
    75421 cactagaatt catagtctag aaagtggtaa ggcttttcta aaatggttga ttttgtaatc
    75481 ttttttgtaa aatatagctt ttaataaata atgtgagcaa gatatatctc tttgcaagtg
    75541 attagggtca atagttttta actttctcac ttcttttccg aataaataga tagaaccata
    75601 gaatctagca aaattagatt taaaactatg gtataataga gggaggagaa ggataattct
    75661 cagacatccg ggcatcagcc caaccaatga cttagttgct aagaaaatct ttagcaatcc
    75721 ggaaatcact tgtcaattta ttcgcgatat gctggacttg ccagcaaaaa atgtgactat
    75781 tttggaggga agtaacattc atgttttgcc ttctatgcct tactcagctc aagattttta
    75841 cactagtata gacgtcttgg cggagttgga taatggtact caagtaatca ttgagattca
    75901 ggtgcatcat cagaattttt tcatcaatcg cttgtggact tacctgtgca gtcaggtcaa
    75961 tcaaaaccta gaaaaaattt gccaacgaga aggtgataca caccatagtt acaaacatat
    76021 cgcaccagtt tatgctattg ccatcgtaga tagtaattac ttccaagatg atttggcctt
    76081 tcacagtttt agtatgcgcg aagacacgac aggtgaggtc ttaactatca caactaacgg
    76141 tcaagaaaac catttggtca agatggcatt cttggaacta aaaaaataca gagaaaccag
    76201 caaagacgag gttcgtaagc cgtggttgga gtttttcggg aacaaaccct ttacccaaga
    76261 acccgagcga gccatcagcc aagcagacca actgctggac tacaagagct ggtccgagga
    76321 ggacagaaaa atgtttagtc aactacgtat gcgagaagaa caggcattat tggctcatga
    76381 ctattccttg gaacaagctg aggaaaaagg gttggagaga ggtcgtgcag aaggacttga
    76441 acgtggtctt gaacgtggaa aactttttgc ctttctggat atggttcgcc aaggacttct
    76501 gacttccgag gttgccagtc agcagttggg catgaccgtt gctgagtttg aggcgttgtt
    76561 gtaagatcag caataataga caggaaaacc atctggtcaa gatggcgttc ttggaattaa
    76621 aaaactctag gtataaaatc ttaaaaatta caaacacgca tagtatcagg ggattaagaa
    76681 accttgatac tatgcgtttt atagtgcatt gaatctacat tagtacacta tagttgattg
    76741 aaaacagaat agtataccgc agcttctaaa tccttgttat aaatttgatt tgactttcct
    76801 aatcgattta ttctcatctt atttcaatct gctatattta cttcactttc tcctaaaatt
    76861 gactttcttg ttttcttatc ttgtccactc gaaacaagta ttgtaagaat ttgattattt
    76921 ttgaaagtac ttttaatata cttgatatag ttaaaaaaga tttgaaacta aattccaaat
    76981 tagaaaaaga cttgaaatac taaaaaaaaa aaagtatact ctaattgaaa acggtaacaa
    77041 aactaattta gagaatgaaa tatagagtat ttctctctta aaagtttttg gtgaaacgag
    77101 atgtagaaag gagatttagc caaagagtct attagtgcta gaataataga ttagaattat
    77161 tttagaaaaa cgaagtgagc agcttataaa ttcaagtccc caaatagatt catactagta
    77221 tcttttgcaa aaaataaagg gcgacttcct tcatgaatat caatttcatc tataaggaag
    77281 gtagctaatt gaactaactt atttattctg tttgtcgcta gaaaaatcag acctccttgt
    77341 gaagattgag gagatactta atgaaaatca aagaagaaac tagcaagcta gtagcagatt
    77401 gcccaaaaca ccgctttgag gttgtagata agactgacgt atataatcca aggtgaagcg
    77461 actgtggttt gaagagattt tcaaagagta taggctagag agtagtgttt ttatgtcctt
    77521 ctagtagaaa atgctagaca gaagaatggg gaacttggat aggaaaaata gattgagaaa
    77581 ggaggttaga agagatgatt attacaaaaa ttagccgttt aggaacttat gtgggagtaa
    77641 atccacattt tgcaacatta atagattttc tagaaaaaac aggactagaa aatttaacag
    77701 aaggttcgat tgctatcgat ggtaatcgat tgtttgggaa ttgctttact tatctagcag
    77761 atggtcaagc aggggctttc tttgaaacac accaaaaata tttggatatt catttagttt
    77821 tggaaaacga agaagccatg gctgttacat cgccggaaaa tgtaagcgtt acccaagagt
    77881 atgatgaaga gaaagatatt gaattataca cagggaaagt ggaacagttg gttcatttga
    77941 gagctggcga atgcctcatc acttttccag aagatttaca tcaacccaag gttcgtataa
    78001 atgatgaacc tgtgaaaaaa gttgtcttta aagttgcgat ttcttaatgt agaaagagaa
    78061 gaacgatgaa aaaaatgaga aagtttttat gtctagctgg aattgcgcta gcggctgttg
    78121 ccttggtagc ttgttcagga aaaaaagaag ctacaactag tactgaacca ccaacagaat
    78181 tatctggtga gattacaatg tggcactcct ttactcaagg accccgttta gaaagtattc
    78241 aaaaatcagc agatgctttc atgcaaaagc atccaaaaac gaaaatcaag attgaaacat
    78301 tttcttggaa tgacttctat actaaatgga ctacaggttt agcaaatgga aatgtgccag
    78361 atatcagtac agctcttcct aaccaagtaa tggaaatggt caactcagat gctttggttc
    78421 cgctaaatga ttctatcaag cgtattggac aagataaatt taacgaaact gccttaaatg
    78481 aagcaaaaat cggagatgat tactactctg ttcctcttta ttcacatgca caagtcatgt
    78541 gggttagaac agatttgtta aaagaacata atattgaggt tcctaaaact tgggatcaac
    78601 tctatgaagc ttctaaaaaa ttgaaagaag ctggagttta tggcttgtct gttccgtttg
    78661 gaacaaatga cttaatggca acacgtttct tgaacttcta cgtacgtagt ggcggaggaa
    78721 gcctcttaac aaaagatctt aaagcagact tgacaagcca acttgctcaa gatggtatta
    78781 aatactgggt taaattgtat aaagaaatct cacctcaaga ttctttgaac tttaatgtcc
    78841 ttcaacaagc taccttgttc tatcaaggaa aaacagcatt tgactttaac tctggcttcc
    78901 atatcggagg aattaatgcc aacagtcctc aattgattga ttcgattgat gcttatccta
    78961 ttccaaaaat caaagagtct gataaagacc aaggaattga aacctcaaac attccaatgg
    79021 ttgtttggaa aaattcaaaa catccagaag ttgctaaagc attcttagaa gcactttata
    79081 atgaagaaga ctacgttaaa ttccttgatt caactccagt aggtatgttg ccaactatta
    79141 aggggattag cgattctgca gcctataaag aaaatgaaac tcgtaagaaa tttaaacatg
    79201 ctgaagaagt aattactgaa gctgttaaaa aaggtactgc tattggttat gaaaatggac
    79261 caagtgtaca agctggtatg ttgactaacc aacacattat tgaacaaatg ttccaagata
    79321 tcattacaaa tggaacagat cctatgaaag cagcaaaaga agcagaaaaa caattaaacg
    79381 atttatttga ggctgttcag tagatgtaaa agactagaaa ataggtgggc tagtgagctg
    79441 aaaagctcta gcccaatctt gtaaaagaag ggagaaggag aatggttaaa gaacgtaatt
    79501 taactcgctg gatatttgtt ttgccagcta tgattatcgt aggattactc tttgtttatc
    79561 cgtttttctc gagtattttt tatagcttta ccaataagca tttgattatg cctaattata
    79621 aatttgttgg tttggctaac tataaagctg tgctatcaga tcccaacttc tttaatgcgt
    79681 tctttaattc aattaagtgg accgttttct cattagttgg tcaagtttta gtagggtttg
    79741 tattggcttt agctcttcac agagtacgcc acttcaagaa attatatagg accttattga
    79801 ttgttccttg ggcatttcct accatcgtta ttgccttttc ttggcagtgg attctaaacg
    79861 gggtttatgg ctacttacct aatctaatcg taaaattagg tttaatggaa catacacctg
    79921 catttttgac agatagtaca tgggcattcc tatgtttggt gtttatcaac atttggtttg
    79981 gagcaccaat gattatggtt aatgtgcttt cagctttgca aacagtacca gaagaacaat
    80041 ttgaggctgc taagatagat ggtgcttcaa gttggcaggt gttcaagttt atcgtctttc
    80101 cacatattaa agtggttgta ggacttctag ttgttttgag aactgtatgg atctttaata
    80161 actttgacat tatctaccta attactggtg gtggaccagc caatgctaca acgacgcttc
    80221 caatttttgc ttacaacctg ggttggggaa ctaaattgtt gggtcgtgct tcagcagtta
    80281 cagtattgct ctttatcttc ttggtggcga tttgctttat ctactttgct atcatcagta
    80341 agtgggaaaa ggagggtaga aaataatgaa gaagaaatcc agtatttatt tagatattct
    80401 ctcacatgta cttttagttg gtgcgaccat cgttgcaatt ttcccattgg tatggattat
    80461 catatcttct gtcaaaggga aaggggaatt aactcagtat ccaacacgat tttggcctga
    80521 acagtttaca ttagattatt tcactcatgt tatcaacgat ttgcacttca ttgataatat
    80581 tcgaaacagt ttaatcattg ccttggctac aaccctcatt gcgattatta tttctgctat
    80641 ggcagcctat ggtattgttc gattctttcc taaattggga gcaatcatgt cgagactact
    80701 cgtcattacc tacattttcc caccaatttt gttagcaatt ccctattcaa ttgccattgc
    80761 taaagttggg ttaacaaata gtttatttgg cttgatgatg gtttatctat cttttagtgt
    80821 tccatatgca gtttggctct tagttggatt tttccaaaca gttccaattg gaattgaaga
    80881 agcggctaga attgatggtg caaataaatt tgttacgttt tataaagttg tgctaccgat
    80941 tgtagcacca ggtattgtag caacagctat ttatacattt atcaatgctt ggaatgaatt
    81001 cctgtatgcc ttgattttga ttaacaatac aggaaagatg acagtagcag tagcccttcg
    81061 ttcacttaat ggttcagaaa tactagactg gggagatatg atggcagcgt ctgttattgt
    81121 agttcttcca tcaattattt tcttctctat catccaaaat aagattgcaa gtggattatc
    81181 agaaggatct gtgaagtaga cgaaagaagg aaaaaaatga ataaaagagg tctttattca
    81241 aaactaggaa tttctgttgt aggcattagt cttttaatgg gagtccccac tttgattcat
    81301 tcgaatgaat taaactatgg tcaactgtcc atatctccta tttttcaagg aggttcatat
    81361 caactgaaca ataagagtat agatatcagc cctttgttat tagataaatt gtctggagag
    81421 agtcagacag tagtaatgaa atttaaagca gatgaaccaa actctcttca agctttgttt
    81481 ggcctatcta atagtaaagc aggctttaaa aataattact tttcaatttt catgagagat
    81541 tctggtgaga taggtgtaga aataagagac gcccaaaagg gaataaatta tttattttcc
    81601 agaccagctt cattatgggg aaaacataaa ggacaggcag ttgaaaatac actagtattt
    81661 gtatctgatt ctaaagataa aacatacaca atgtatgtta atggaataga agtgttctct
    81721 gaaacagttg atacattttt gccaatttca aatataaatg gtatagataa ggcaacacta
    81781 ggagctgtta atcgtgaagg taaggaacat taccttgcaa aaggaagtat tgatgaaatc
    81841 agtctattta acaaagcaat tagtgatcag gaagtttcaa atattccctt gtcaaatcca
    81901 tttcagttaa ttttccaatc aggagattct actcaagcta actattttag aataccgaca
    81961 ctatatacat taagtagtgg aagagttcta tcaagtattg atgcacgtta tggtgggact
    82021 catgattcta aaagtaagat taatattgcc acttcttata gtgatgataa cgggaaaacg
    82081 tggagtgagc caatttttgc tatgaagttt aatgactatg aggagcagtt agtttactgg
    82141 ccacgagata ataaattaaa gaatagtcaa attagtggaa gtgcttcatt catagattca
    82201 tccattgttg aagataaaaa atctgggaaa acgatattac tagctgatgt tatgcctgcg
    82261 ggtattggaa ataataatgc aaataaagcc gactcaggtt ttaaagaaat aaatggtcat
    82321 tattatttaa aactaaagaa gaatggagat aacgatttcc gttatacagt tagagaaaat
    82381 ggtgtcgttt atgatgaaac aactaataaa cctacaaatt atactataaa tgataagtat
    82441 gaagttttgg agggaggaaa gtctttaaca gtcgaacaat attcggttga ttttgatagt
    82501 ggctctttaa gagaaaggca taatggaaaa caggttccta tgaatgtttt ctacaaagat
    82561 tcgttattta aagtgactcc tactaattat atagcaatga caactagtca gaatagagga
    82621 gagagttggg aacaatttaa gttgttgcct ccgttcttag gagaaaaaca taatggaact
    82681 tacttatgtc ccggacaagg tttagcatta aaatcaagta acagattgat ttttgcaaca
    82741 tatactagtg gagaactaac ctatctcatt tctgatgata gtggtcaaac atggaagaaa
    82801 tcctcagctt caattccgtt taaaaatgca acagcagaag cacaaatggt tgaactgaga
    82861 gatggtgtga ttagaacatt ctttagaacc actacaggta agatagctta tatgactagt
    82921 agagattctg gagaaacatg gtcggaagtt tcgtatattg atggaattca acaaacttca
    82981 tatggcacac aagtatctgc aattaaatat tctcaattaa ttgatggaaa agaagcagtc
    83041 attttgagta caccaaattc tagaagtggc cgtaagggag gtcaattagt tgtcggttta
    83101 gtcaataaag aagatgatag tattgattgg aaatatcact atgatattga tttgccttcg
    83161 tatggttatg cctattctgc gattacagaa ttgccaaatc atcatatagg tgtactgttt
    83221 gaaaaatatg attcgtggtc gagaaatgaa ttgcatttaa gcaatgtagt tcagtatata
    83281 gatttggaaa ttaatgattt aacaaaataa aggagaaaaa catggttaaa tacggtgttg
    83341 ttggaacagg gtattttgga gctgaattgg ctcgctacat gcaaaagaat gatggagcag
    83401 agattactct tctctatgat ccggataata cagaggcgat tgcagaagaa ttgggagcaa
    83461 aagtagcaag ttccttagat gagttggttt ctagcgatga agtagattgt gtcatcgtcg
    83521 caactccaaa taatcttcat aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg
    83581 ttttctgtga aaaaccaatt gcgctttctt atcaagattg tcgcgagatg gtagatgcat
    83641 gtaaagaaaa caatgtaacc tttatggcag gacatattat gaatttcttt aatggtgttc
    83701 atcgtgcaaa agaactcatt aatcaaggag ttatcggaga cgttctatat tgtcatacag
    83761 ctcgtaatgg ttgggaagaa caacaaccgt cagtatcatg gaaaaaaatt cgtgaaaaat
    83821 caggtggtca cttgtatcac cacatccatg aattggattg cgttcaattc cttatggggg
    83881 gcatgcctga aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg
    83941 gtgatgaaga tgatatgatt tttgtcaata tggaattttc taataagcgt tttgccttgt
    84001 tagaatgggg ttcagcttat cgttggggtg aacattatgt cttaatccaa ggaagcaaag
    84061 gtgccatccg cttagactta ttcaactgta aaggaactct taagctagat gggcaagaaa
    84121 gctatttctt gattcacgaa tcgcaagaag aagatgatga tcggactcgt atctatcata
    84181 gtacagagat ggatggagca attgcttatg gtaaaccagg taaacgtact ccattatggc
    84241 tatcatctgt cattgataaa gaaatgcgct atctgcatga gattatggaa ggagctccag
    84301 tatcagaaga atttgcaaaa cttttgacag gtgaagctgc cctagaagca attgctactg
    84361 cagatgcttg tacccagtct atgtttgaag atcgcaaagt aaaattgtca gaaattgtaa
    84421 aataaatttt ggtattctcc tattataggt cgacttgctc ctctgaaagt acttttagag
    84481 gagctgtttg acttggctag tttttgaaac tgaaatctat tatactacaa actattgaaa
    84541 gcgttttaat tttaaggtat aataatctca tagaaataaa gaaaaggagg aaagaggatg
    84601 ccacagatta gcaaagaagc cttgattgag caaatcaaag atggaatcat cgtttcttgt
    84661 caggctcttc ctcatgaacc gctttataca gaagcgggag gggtgattcc cttgctggtc
    84721 aaagcggctg agcaaggtgg agcagtcggt atccgagcaa acagtgttcg cgatatcaag
    84781 gaaattaagg aagtcactaa acttccaatc attgggatta tcaaacgtga ttatccacct
    84841 catgaaccct tcatcacggc tactatgaaa gaagttgatg aattggcaga actggacatc
    84901 gaggtgattg ctctggattg taccaagcgt gaacgctacg atggtttgga aattcaagag
    84961 ttcattcgtc aggttaagga gaaatatcct aatcagcttt tgatggctga tactagtatc
    85021 ttcgaagaag ggctagcagc tgtaaaagca ggaattgact ttgtcggaac aaccttatca
    85081 ggctacacat cctacagtcc aaaagtagac ggtccagatt ttgaattgat taagaaactc
    85141 tgtgatgccg gtgtagatgt cattgcagaa ggaaaaattc atacaccaga acaagccaaa
    85201 caaatccttg aatatggagt gcgaggcatc gttgttggtg gcgctattac tagaccaaaa
    85261 gagattacag aacgcttcgt tgctagtctt aaataagatg tgagggggag ttttatgttt
    85321 aaagttttac aaaaagttgg aaaagctttt atgttaccta tagctatact ttctgcagca
    85381 ggtctacttt tggggattgg tggtgcactt tcaaacccaa ccacgatagc aacttatcca
    85441 atactagaca atagtatttt tcaatcaata ttccaagtaa tgagctctgc aggagaggtt
    85501 gtattcagta atttgtcact acttctctgt gtgggattat gtattggctt agcgaaacga
    85561 gataaaggaa ccgctgcgtt agcaggagta actggttact tagttatgac tgtaacgatc
    85621 aaagctttgg taaaactttt tatggcagaa ggatctgcaa ttgatactgg agttattgga
    85681 gcattagttg tcggaatagt tgccgtatat ttgcacaatc gatataacaa tattcaatta
    85741 ccttccgctt taggattctt tggaggttca cgcttcgttc ctattcactt tatttggaat
    85801 tttgcagggg aacgctaaga cgaattgggt tcttcagatt ccatttggac ttatttggag
    85861 tgttttgtat tatattattt ttagatggtt cattactcaa ttcaacgttc taacgccagg
    85921 acgaggagaa gaagtagatt ctaaagaaat ttctgaatcc gcagattcaa cttcaaatac
    85981 tgcagattat ttaaaacagg atagcctaca aattatcaga gccttgggtg gatcaaataa
    86041 tatagaagat gtagatgctt gtgtgacacg tttacgtgta gctgtaaaag aagttaatca
    86101 agttgataaa gcacttttaa aacaaattgg tgcagttgat gtcttagaag tgaagggtgg
    86161 cattcaagca atctatggag caaaagcaat cttatataaa aatagtatta atgaaatttt
    86221 aggtgtagat gattaagtac ttactgactt aataaaaaac agaggagagt gatggatgag
    86281 taggatgaaa tgaaatcgca tacaagaaat aaagaactca ttatccaagt tggatacgct
    86341 tattacatag gagaatacaa atgaaattta gaaaattagc ttgtacagta cttgcgggtg
    86401 ctgcggttct tggtcttgct gcttgtggca attctggcgg aagtaaagat gctgccaaat
    86461 caggtggtga cggtgccaaa acagaaatca cttggtgggc attcccagta tttacccaag
    86521 aaaaaactgg tgacggtgtt ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag
    86581 caaacccaga tataaaagtg aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa
    86641 tcacaacagc catcgaagca ggaacagctc cagacgtact atttgatgca ccaggacgta
    86701 tcatccaata cggtaaaaac ggtaaattgg ctgagttgaa tgacctcttc acagatgaat
    86761 ttgttaaaga tgtcaacaat gaaaacatcg tacaagcaag taaagctgga gacaaggctt
    86821 atatgtatcc gattagttct gccccattct acatggcaat gaacaagaaa atgttagaag
    86881 atgctggagt agcaaacctt gtaaaagaag gttggacaac tgatgatttt gaaaaagtat
    86941 tgaaagcact taaagacaag ggttacacac caggttcatt gttcagttct ggtcaagggg
    87001 gagaccaagg aacacgtgcc tttatctcta acctttatag cggttctgta acagatgaaa
    87061 aagttagcaa atatacaact gatgatccta aattcgtcaa aggtcttgaa aaagcaacta
    87121 gctggattaa agacaatttg atcaataatg gttcacaatt tgacggtggg gcagatatcc
    87181 aaaactttgc caacggtcaa acatcttaca caatcctttg ggcaccagct caaaatggta
    87241 tccaagctaa acttttagaa gcaagtaagg tagaagtggt agaagtacca ttcccatcag
    87301 acgaaggtaa gccagctctt gaatatcttg taaacgggtt tgcagtattc aacaataaag
    87361 acgacaagaa agtcgctgca tctaagaaat tcatccagtt tatcgcagat gacaaagagt
    87421 ggggacctaa agacgtagtt cgtacaggtg ctttcccagt ccgtacttca tttggaaaac
    87481 tttatgaaga caaacgcatg gaaacaatca gcggctggac tcaatactac tcaccatact
    87541 acaacactat tgatggattt gctgaaatga gaacactttg gttcccaatg ttgcaatctg
    87601 tatcaaatgg tgacgaaaaa ccagcagatg ctttgaaagc cttcactgaa aaagcgaacg
    87661 aaacaatcaa aaaagctatg aaacaatagt ccttagttat tctataaaaa gtagtttttt
    87721 aaagaaccta agagtgtata cccccttttc cctctacaca gatagtgtaa gaaaaggggg
    87781 cttttgttta aaatgtaaga aactgtcacg aaattaaaat gaagttctta cataagcgaa
    87841 tcataaaaaa tttcattttg attttaaaac agttcaagaa agtcaaaaaa ttattctatt
    87901 tgaaagagag gtgccgactg tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc
    87961 ctacgctttc ctagcaccag tattattctt ctttgtcatc tttgtgttgg ctccgatggt
    88021 gatgggcttc attacaagtt tctttaacta ctcaataact aaatttgagt ttgtaggctt
    88081 ggataactat atccgtatgt ttaaagatcc tgtctttaca aaatctctga ttaacacagt
    88141 tattttggtt attggatctg taccagttgt tgttctattc tcactctttg tagcatctca
    88201 gacctatcat caaaatgtca ttgccagatc cttctaccgt ttcgtcttct tccttcctgt
    88261 tgtaacgggt agtgttgccg tgacagttgt ttggaaatgg atttatgacc cactatcagg
    88321 gattctaaac tttgtcctta agtcaagcca catcatcagc caaaacattt cttggttggg
    88381 agataaaaac tgggcattga tggcgattat gattattctc ttgaccactt cagttggtca
    88441 gcccatcatc ctttatatcg ctgccatggg gaatattgac aattcactgg ttgaagcggc
    88501 gcgtgttgat ggtgcaactg agtttcaagt tttttggaag attaaatggc caagccttct
    88561 tccaacaact ctttatattg caatcatcac aacaattaac tcattccagt gtttcgcctt
    88621 gattcagctt ttgacatctg gtggtccaaa ctactcaaca agtaccttga tgtactacct
    88681 ttacgaaaaa gccttccaat tgacagaata cggctatgcc aacacaattg gtgtcttctt
    88741 ggcagtcatg attgctatcg taagctttgt tcaatttaaa gtacttggaa acgacgtaga
    88801 atactaaaga aaggagacag ctatgcaatc tacagaaaaa aaaccattaa cagcctttac
    88861 tgttatttca acaatcattt tgctcttgtt gactgtgctg ttcatctttc cattctactg
    88921 gattttgaca ggggcattca aatcacaacc tgatacaatt gttattcctc ctcagtggtt
    88981 ccctaaaatg ccaaccatgg aaaacttcca acaactcatg gtgcagaacc ctgccttgca
    89041 atggatgtgg aactcagtat ttatctcatt ggtaaccatg ttcttagttt gtgcaacctc
    89101 atctctagca ggttatgtat tggctaaaaa acgtttctat ggtcaacgca ttctatttgc
    89161 tatctttatc gctgctatgg cgcttccaaa acaagttgtc cttgtaccat tggtacgtat
    89221 cgtcaacttc atgggaatcc acgatactct ctgggcagtt atcttgcctt tgattggatg
    89281 gccattcggt gtcttcctca tgaaacaatt tagtgaaaat attcctacag agttgcttga
    89341 atcagctaag attgacggtt gtggtgagat tcgtactttt tggagcgtag ccttcccaat
    89401 tgtaaaacca gggtttgcgg ctcttgcaat cttcaccttc atcaatactt ggaatgacta
    89461 cttcatgcag ttggtaatgt tgacttcacg taacaatttg accatctcac ttggggttgc
    89521 gaccatgcag gccgaaatgg caaccaacta tggtttgatt atggcaggag ctgcccttgc
    89581 tgctgttcca atcgtcacag tcttcctagt cttccaaaaa tccttcacac agggtattac
    89641 tatgggagcg gtcaaaggat aatactctac catgaaattg atctttgtga ggtagagaaa
    89701 tgagaataaa atatttaaaa attggtatct tctaagtatg ctgcaagagc tagtttctta
    89761 gatggacagg ggattacagt tgatgagatg gcttggataa ttaatggcat tgtgaatgga
    89821 ttgattggta gatacataaa attaggtact tatgcagcta agtatggtat tagtatggcg
    89881 cgctcgatct taagtagggc agctgcaact gcggcagcaa gagtaggatt attgactaag
    89941 atttttggat ggattttacg aatagctgtg ctcggagctg atgtatatgg taattttgcc
    90001 aacaatattg ctgtagcttg ggatgcacat gataaaatcc ctaacaatgg tcgtataaac
    90061 ttttaaaatg cgagaatgaa agcactttgt atttttttat tgaatatgtt agcttggaca
    90121 gtgcttgcaa tgacagtccg tggagggcta gatggattta atgagcatac ttggagtact
    90181 attttaattg cttcgctgtc cgggatatat atagattata tgtccataga taaaagtaga
    90241 aaaaagtcca aaagaaaaaa gaaaaaatag atttgttcat ggtagggact tatgaaagct
    90301 ttactgacaa aaaagaaaac agtttacaaa gaaaaatgat ggaggagcaa acatggcaca
    90361 aaaaggagta agccttatca aggcagcatt tgatacagac aactttctca tgcgttttag
    90421 tgagaaagtc ttggacatcg tgacagccaa tcttcttttt gtcgtctctt gtttgcccat
    90481 cgtgacgatt ggagtggcta aaatcagcct ctacgagacc atgtttgaga ttaagaagag
    90541 cagacgggtg cctgttttta aaatctatct aagatctttc aagcaaaatc tgaaactagg
    90601 tcttcagctg ggtttaatgg agttaggaat tgtgtttctt accctttcag atctctatct
    90661 tttctggggt caaacagctc tgcccttcca attgctgaaa gccatttgtt taggtattct
    90721 gatttttctt actatcgtga tgctggctag ttaccctatc gcggcacgtt atgacctatc
    90781 ttggaaagaa attcttcaaa aagggcttat cttggcaagt tttaactttc cttggttctt
    90841 cctcatgtta gccattcttg tcctcattgt gatggttctc tatctgtccg ccttcagtct
    90901 acttttaggt ggctcagtct tcctgctttt tgggtttgga ctattggtct ttatccagac
    90961 tggattgatg gagaaaattt tcgcaaaata ccaataggag ccttatttct gaaactactt
    91021 tcaaaggctc caaacgctat tctataagcg agaaactaaa atctaagtgt ctataagata
    91081 ttgaaagcct tttcggtaaa gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga
    91141 aaataaaaat aataggagaa aatctatgtc agatttgaaa aaatacgaag gtgtcattcc
    91201 agccttctac gcatgttatg atgagcaagg agaagtaagt ccagagcgta cgcgtgcctt
    91261 ggttcaatac ttcattgata aaggtgttca aggtctttat gtcaatggtt cttctggtga
    91321 atgtatctac caaagcgttg aagatcgcaa gttgattttg gaagaagtca tggcggtagc
    91381 caaaggtaaa ttgaccatta ttgcccatgt tgcttgcaat aatactaaag atagtatgga
    91441 acttgctcgc catgctgaaa gcttgggagt agatgctatt gcaacgattc caccaattta
    91501 cttccgcttg ccagaatact cagttgctaa atactggaac gatattagtt ctgcagctcc
    91561 aaatacagac tacgtgattt ataacattcc tcaattggca ggtgttgctt tgactccaag
    91621 cctttacact gaaatgttga aaaatcctcg tgttatcggt gtgaagaact cttctatgcc
    91681 agttcaagat atccaaacct ttgtgagcct tggtggggaa gaccatatcg tctttaacgg
    91741 tccagatgaa cagttcctag gtggtcgcct catgggtgcc aaagctggta tcggtggtac
    91801 ttatggtgct atgccagaac tcttcttgaa actcaaccaa ttgattgcgg ataaagattt
    91861 agaaacagcg cgtgagttac agtatgctat caacgctatc attggtaaat tgactgctac
    91921 acatggaaat atgtacggtg tcatcaaaga agttttgaag atcaatgaag gcttgaatat
    91981 tggttctgtt cgttcaccat tgacaccagt gactgaagaa gatcgtccag ttgtagaagc
    92041 ggctgctgcc ttgattcgtg aaaccaagga gcgcttcctc taatctaaaa ggaggtattt
    92101 atgacatact acgttgcaat tgatatcggt ggaaccaaca tcaagtatgg tttggttgat
    92161 caagaggggc aacttcttga atcgcatgaa atgccaactg aggcgcataa gggtggacct
    92221 catatcttac aaaagaccaa agatatcgta gctagttatt tagaaaaagg cccagtagca
    92281 ggtgttgcca tatcttctgc tgggatggtg gatccggata agggtgagat tttctatgct
    92341 gggccgcaaa tccctaacta cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt
    92401 actattcctt gtgagattga aaatgatgtc aactgtgcag gtcttgctga ggcagtatct
    92461 ggttcaggca agggagcaag tgtgacactt tgcttgacca ttggaacagg tatcggtggt
    92521 tgcttgatta tggataggaa agtcttccat ggttttagca attcagcctg tgaagtcggg
    92581 tatatgcata tgcaggatgg agcttttcaa gacttggctt ctacaacagc tttagtgaaa
    92641 tatgtagctg aagcccatgg agaagatgtt gatcagtgga atggccgacg tatctttcag
    92701 gaagctactg aaggaaacaa aatctgcatg gaaggcattg accgtatggt tgactatcta
    92761 ggaaaaggtc tggcaaatat ttgctacgtt gccaatccag aagtggtcat tcttggtgga
    92821 ggtatcatgg ggcaagaggc tatcctcaaa cctaagatcc gcacagcctt gaaagaggct
    92881 ttggtaccaa gtttagcaga aaaaacacga ttagaatttg cccatcacca aaatacagca
    92941 gggatgttgg gtgcatatta tcattttaag acaaaacaat cctagtttgg ctcagccaaa
    93001 ctaggatttt cttacacgtt tttgtctacg atagccgttg agttttttat tttcccagta
    93061 gctattaaag attttttcct tgctttcgcg attgatttcc aaaaagtagg cataaatcaa
    93121 atcgataaag aagagcatag gaagttgagc ggatattcgt tggatatagg agggttggct
    93181 gtgggtggct acaagaacag tctctgtata ggtctggcta tctttattgg gaacacttgt
    93241 aaagagtaca gtctttgccc ccatctcctt ggcatctaat agactatcta aaatagaagg
    93301 agttgagcct gaaagtgaga agcccagtac tagacaattt tcatccatga tgctggttgt
    93361 ccaggcaaag ccgtcttggt ctgtcaaagc ttcgcagacc acacctagtc gcataaaacg
    93421 taatttcatt tcacgggcga cgaggccaga actccctgtt ccaaagaagt agatacgctc
    93481 agcatcttcg attagctggg caattcgctc tagttggatt tcgtcaatca agtcttgtgt
    93541 ttgttccctc atattgctat aacttctgag gactcgtttg gtcagtggac tgtgcttgga
    93601 gacttggttg gcttgatttt ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc
    93661 ggtaaagcca cactttttag caaagcgggt caaagcagct tgagaaatat gtaatttttg
    93721 ggtgacttgt tgagaagata aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc
    93781 gatttcttgc tctaggtctg tcatttcttc aaaatgtgaa tcaatgatag ttgcgatatc
    93841 tggtttgtcc atagggaaag ctcctttaca tgagtcatac tggaagacta gatcagggaa
    93901 tagtcacact tcattataac acataatata aggatagata aataaaaacg catctctgtt
    93961 ttaaaaacga aaaaatcgaa aaagcttctt tcttttccat aattttctac tcaaattgtg
    94021 gtacaattaa gagtaagatt ttaagttaga aatgagactg atttgtatga gaaaatttaa
    94081 cagccattcg attccgattc ggcttaattt attgttttca atcgtcattt tactctttat
    94141 gaccattatt ggtcgtttgt tgtatatgca ggttttgaac aaggattttt acgaaaaaaa
    94201 gctagcctca gctagtcaga ccaagattac aagcagttca gcccgtgggg aaatttatga
    94261 tgctagtgga aaacctttgg tagaaaatac gttaaagcag attgtttcct ttacgcgtag
    94321 caataaaatg acggctacag acttaaaaga aacagctaaa aagttactga cttatgtgaa
    94381 catcagctcg ccaaatttga cagaacgcca gctggcggat tactatttgg ctgatcctga
    94441 aatctataaa aaaacagtgg aagctctccc aagcgagaaa cgcttggatt cagatggcaa
    94501 tcgtctatcc gaatcagaac tgtataacaa tgcggtcgat agtgtccaaa caagtcaatt
    94561 aaactataca gaggatgaaa agaaagaaat ctatcttttt agtcagttaa atgctgttgg
    94621 aaactttgcg acaggaacca ttgctacaga tcctctaaat gattctcagg tggctgttat
    94681 tgcctctatt tcaaaggaga tgcctggcat tagtatttct acttcttggg atagaaaggt
    94741 tttggaaact tccctttctt ctatagttgg gagtgtatcc agtgaaaaag ctggtctccc
    94801 agcggaagaa gcagaagcct atcttaaaaa aggctattct ctaaatgatc gtgtaggaac
    94861 ctcctatttg gaaaagcaat atgaagagac cttacaagga aaacgctcgg taaaagaaat
    94921 ccatctggat aaatatggca atatggaaag cgtggataca attgaggaag gtagtaaggg
    94981 aaacaatatc aaactgacca ttgatttggc cttccaagat agcgtggatg ctttgctgaa
    95041 aagttatttc aattctgagc tagaaaatgg tggagccaag tattctgaag gtgtctatgc
    95101 agtcgccctt aacccaaaaa caggtgcggt tttgtctatg tcagggatta aacatgactt
    95161 gaaaacggga gagttgacgc ctgattcctt gggaacggta accaatgtct ttgttccagg
    95221 ttcggttgtc aaggcggcga ccatcagctc aggttgggaa aatggagtct tgtcaggaaa
    95281 ccagaccttg acagaccagt ccattgtctt tcaaggttca gctcctatca attcttggta
    95341 tactcaggct tacggttcat tccctatcac agcagtccaa gctctggagt attcatctaa
    95401 tgcctatatg gtccaaacag ccttaggtct tatggggcag acctaccaac ccaatatgtt
    95461 tgtcggcacc agcaatctag agtctgctat ggggaaattg cgttcaacct ttggtgaata
    95521 tggtttgggt tctgcgaccg ggattgacct accagatgaa tctactggat ttgttcccaa
    95581 agagtatagc tttgccaatt acattactaa tgcctttggg cagtttgata actatacgcc
    95641 catgcagttg gctcagtatg tagcaactat tgcaaatgat ggtgttcgtg tggctcctcg
    95701 tattgttgaa ggtatttatg gcaataatga taagggagga ctgggtgact tgattcagca
    95761 actgcaaccg acagagatga ataaggtcaa tatatccgac tccgatatga gcatcttgca
    95821 ccaaggtttt tatcaggttg ctcatgggac tagcggcttg acaactggac gtgccttttc
    95881 aaatggtgcc ttggtatcca ttagcggaaa aacgggtaca gccgaaagct atgtggcaga
    95941 tggtcagcaa gcaaccaata ccaatgcggt ggcctatgcc ccatctgata atccccaaat
    96001 cgctgttgca gtggtctttc ctcataatac caatctaaca aatggtgtag gaccttccat
    96061 tgcgcgtgac attatcaatc tgtatcaaaa ataccatcca atgaattaga aaggaaatta
    96121 tgctttatcc aacacccatt gccaagctga ttgacagtta ttccaagtta ccaggtatcg
    96181 ggattaagac ggctacgcgt ctggcctttt atacgattgg gatgtctgat gatgatgtca
    96241 atgaatttgc aaaaaatctc ctttctgcta agagagaatt gacctactgt tccatttgtg
    96301 gacgtttgac agacgacgat ccttgttcta tctgtaccga tccgactcgt gaccagacaa
    96361 cgattttggt gctagaggat agtcgtgatg tggcggccat ggaaaatatc caagaatacc
    96421 atggcctcta tcatgttctg catggcctca tttctcctat gaatggcatt agtccagacg
    96481 atatcaatct caagagtctc atgactcgtc ttatggatag tgaggtttca gaagtaatcg
    96541 tagcaaccaa tgccacagca gatggggaag cgacttccat gtatctttca cgtttgctca
    96601 agccagctgg catcaaggtt acgcgcctgg cgcgaggcct cgctgtggga gcagatatcg
    96661 agtatgcgga cgaagtgacc ctcttacggg ctattgaaaa tcgaacagag ttgtaagtgt
    96721 agacaaattt acgaactcta ttcatttata aaaaatcaaa gaggctgaaa atcgttccta
    96781 tcggcctctt tttgtatagt gtgatgggta ggttcaggtt caagttttaa aaaaacaagc
    96841 aaatgtgata tactaaagag cgagtattct agtagaatta ggacaagtaa tatgaaacaa
    96901 acgattattc ttttatatgg tggacggagt gcggaacgcg aagtctctgt cctttcagcg
    96961 gaaagtgtca tgcgtgcggt taactacgac cgtttcacag ttaagacttt ctttatcagt
    97021 cagtcaggtg attttatcaa aacgcaggaa tttagtcaga ctccaggtca agaggaccgt
    97081 ctcatgacca atgcgaccat tgattgggat aagaaagttt caccaagtgc catctacgaa
    97141 gaaggtgcgg tagtctttcc ggttcttcac ggtccgatgg gggaggatgg ctctgttcaa
    97201 ggattcttgg aagttttgaa aatgccttat gtcggctgta atatcttgtc atcaagtctt
    97261 gccatggata aaatcacgac caagcgtgtg ttagaatctg caggcattgc ccaagttcct
    97321 tatgtggcta tcgttgaagg ggatgatgtg actgctaaaa tcgctgaagt ggaagaaaaa
    97381 ttggcttatc cagtcttcac taagccgtca aacatgggtt ctagtgtcgg tatttctaaa
    97441 tctgaaaacc aagaggaact ccgtcaagct ttgaaacttg ccttccaata tgacagccgt
    97501 gtcttggttg agcaaggggt gaatgcccgt gaaatcgagg ttggactctt gggaaattac
    97561 gatgtcaaga gcacgcttcc aggagaagta gtcaaggatg ttgcctttta tgactacgat
    97621 gccaagtata ttgataacaa gattactatg gatattcctg ccaaaatcag tgatgatgtg
    97681 gtagctgtca tgcgtcaaaa tgcagaaaca gccttccgtg ccattggtgg cctcggtctc
    97741 tctcgttgcg atttcttcta tacagataag gaagagattt tcctaaacga gctgaatacc
    97801 atgccaggct tcacccagtg gtctatgtat ccactacttt gggataatat gggaatcagc
    97861 tacccagacc taatcgagca tttggttgcc cttgctaagg aaagttttga taagcgcgaa
    97921 gcgcatttgc tataaaaatg aaagagaggg tagaagccag aactatcact gcaaggtgat
    97981 cagagttctc ggacttcaac cctttttaaa ggagtagaaa tgaaattaac aatccatgag
    98041 gttgcccaag ctgttggagc taaaaatgat atcagtatct ttgaggacac ccagttagaa
    98101 aaagctgagt ttgatagtcg tttgattgga actggagatt tatttgtgcc acttaaaggt
    98161 gcgcgtgatg gccatgactt tattgaaaca gcctttgaaa atggtgcagc agtaaccttg
    98221 tctgagaaag aggtctcaaa tcatccttac attctagtag atgatgtttt gacagccttt
    98281 caatccttag catcctacta tcttgaaaaa acgactgttg atgtctttgc tgttacaggt
    98341 tcaaatggca agacaacgac taaggatatg ttggcgcatt tactgtcaac aagatacaag
    98401 acctacaaaa cacaaggcaa ttacaataat gagattggcc ttccttacac agttcttcat
    98461 atgcctgaag gaacagaaaa gttggttttg gagatgggac aggatcactt gggcgatatt
    98521 catctcttgt ctgaattggc tcgtccaaaa acagtcatcg tgaccttggt tggagaagcc
    98581 catttggcct ttttcaaaga ccgttcagag attgctaagg gaaaaatgca aattgcagac
    98641 ggaatggctt caggttcctt gcttttagcg ccggctgacc ctatcgtaga ggactatttg
    98701 ccaactgata aaaaggtggt tcgttttggg caaggggcag agctggaaat tactgacttg
    98761 gttgagcgca aagatagtct gaccttcaag gccaatttct tagagcaagc ccttgatttg
    98821 ccagtaactg gcaagtacaa tgcgacaaat gctatgattg catcctatgt tgccttgcaa
    98881 gaaggagttt cagaggagca aattcgtttg gccttccaag atcttgaatt gacgcgtaac
    98941 cgtaccgagt ggaagaaagc agccaatgga gcagatatcc tgtcagatgt ttacaatgcc
    99001 aatccaactg ctatgaaact gattttagag accttctctg ccattccagc caatgaaggt
    99061 ggcaagaaaa ttgcagtgtt ggcggatatg aaggagcttg gtgaccagtc tgttcaactt
    99121 cataatcaga tgattttgag cctttctcca gatgtgcttg ataccgtgat tttctatgga
    99181 caagatattg ctcagttggc tcaattggcc agtcaaatgt tcccaatcgg ccacgtttac
    99241 tacttcaaga aaacagaaga ccaggatcaa tttgaagacc tagtcaagca ggttaaggaa
    99301 agccttggag cctatgacca aatcttgcta aaaggttcta actctatgaa tctagccaaa
    99361 ttggtagaaa gtttagaaaa tgaagccaag tgattttgtt aagtatctgc aaagaatgat
    99421 tgcccttaca gatactggct taacctttac aaaagatcct tttgaccgtg agcgctacga
    99481 ggacttgcga agtctgttat ctgaaatgtt gaatcaggga tcagacctgg atgtagaaga
    99541 agtagcagaa gtcttgaaac caacttcagc ttatgcgact cccttaatgg acgtccgtgc
    99601 ttggattgtt gaggatgaga agatttgtct ggttagggga caaggagagg atagttgggc
    99661 tttgccaggt ggctttggtg aagtcggcta ttctccaact gaaaatattc tcaaggaaat
    99721 tgaagaagaa accggtttta aagccaaagt tgaaagactg ctagctgttt ttgataccaa
    99781 tcgtttccaa ctacagagca aacaatatgc aaagtttgtt tttgaatgta agcttctcga
    99841 tggacaattc caagaaaatc aagaaatcgc tgaccttcaa ttttttgcaa ttgaccaact
    99901 gccgaattta tctgaaaaac gcattaccaa ggagcaaatc gagattcttt ggcaggttta
    99961 tcaaggtcag agggagcaat atcttgacta agaagatgat tatcgtattt ctaaattcat
   100021 ttttcttaag tagcatggta taataaaatg caggaaaatt ttgaatcatg aggaagacta
   100081 gatgaattta tgggatattt tctttacgac tcaggcaacc gagccgccca aatttgacct
   100141 tttttggtat gttagcctat ttacgctctt agccttaacc ttttatacag cccatcgcta
   100201 tcgtgaaaag aaggtttacc aacgattttt ccaaatcttg cagactgttc agttaatcct
   100261 tctttatggt tggtactggg tcaatcatat gccactgtca gaaagcctac ccttttacca
   100321 ttgccgtatg gctatgtttg tggtactctt gcttcctggt cagtccaaat ataaacaata
   100381 ctttgcatta ttgggaacat ttgggacatt agcagccttt gtttatccag tgccagatgc
   100441 ttaccctttt ccacatatca ccattctatc ctttatcttt ggtcatttag cactcttggg
   100501 gaactctcta gtttatctat tgagacagta taatgcgcga ttgctggatg tgaagggaat
   100561 ttttctcatg acctttgccc taaatgcctt gatttttgtg gtcaatttgg tgacaggtgg
   100621 cgattacgga tttttgacaa aaccgccatt ggttggggat cacggtctag tagctaatta
   100681 tttacttgtt tcaattgtgc tggtagctac tatcagtttg actaagaaaa tcttagaatt
   100741 ctttttagct caagaagcag aaaaaatgat tgcaaaggaa gcttaacaca gagctttctt
   100801 ttttgctctt agagagtttt tacaagcagc ttataaaata agaatttctg aatagacaaa
   100861 ctcaaaaaat ggctgggaaa tttaggaaaa aagcaagcac gattaaattt tttgtgttat
   100921 aatattttgt gaatagctat gcctatgttt agctatggaa taatacgaag tgcgaaactt
   100981 ggaagataga gaggaagcga tgtaatggct agagaaggct tttttacagg tctagatatt
   101041 ggaacaagct ctgtcaaggt gcttgtggcc gagcagagaa atggtgaatt aaatgtaatt
   101101 ggcgtgagta atgccaaaag taaaggtgta aaggatggaa ttattgttga tattgatgca
   101161 gcagcaactg ctatcaagtc agccatttcc caagcggaag aaaaggcagg catttcgatt
   101221 aaatcagtga atgtcggctt gcctggtaat cttttgcagg tagaaccaac tcaggggatg
   101281 attccagtaa catctgatac taaggaaatt acggatcaag atgttgaaaa tgttgtcaaa
   101341 tcagctttga caaagagtat gacacctgac cgtgaagtca ttacctttat tcctgaagaa
   101401 tttattgtgg atggtttcca agggattcgt gacccacgtg gcatgatggg ggttcgcctt
   101461 gaaatgcgtg gtttgcttta tacaggacct cgtactatct tgcacaattt gcgtaagacg
   101521 gttgagcgtg caggtgttca ggttgaaaat gttatcattt caccactagc aatggttcag
   101581 tctgttttga acgaagggga acgtgaattt ggtgctacag tgattgatat gggggcaggt
   101641 caaacgactg tcgctacaat ccgtaatcaa gaactccagt tcacacatat tctccaagaa
   101701 ggtggagatt atgtaactaa agatatctcc aaggttttga aaacctctcg caaattagcg
   101761 gaaggcttga aactgaatta cggggaagcc tatccgcctc ttgcaagcaa agaaaccttc
   101821 caagtagagg ttattggaga agtagaagca gtcgaagtga cggaagccta cttgtcagaa
   101881 attatttctg cacgaatcaa gcacatcctt gaacaaatca agcaagaatt agatagaagg
   101941 cgtctattgg acctccctgg tggtattgtc ttaatcggtg ggaatgccat tttaccaggt
   102001 atggttgagc ttgctcagga agtctttggc gtccgtgtca agctttatgt tccaaatcaa
   102061 gttggtatcc gtaatccagc ctttgcgcat gtgattagtt tatcagaatt tgcgggtcaa
   102121 ttaacagaag ttaatctttt ggctcaggga gcgataaaag gtgagaatga cttaagtcat
   102181 cagccaatta gttttggtgg gatgctgcaa aaaacagctc agtttgtaca atcaacgcct
   102241 gttcaaccag ctcctgctcc agaagtagag ccggtggcgc ctacagaacc aatggcggat
   102301 ttccaacaag cttcacaaaa taaaccgaaa ttagcagatc gtttccgtgg attgatcgga
   102361 agcatgtttg acgaataaag aggaaaaata aattatgaca ttttcatttg atacagctgc
   102421 tgctcaaggg gcagtgatta aagtaattgg tgtcggtgga ggtggtggca atgccatcaa
   102481 ccgtatggtc gacgaaggtg ttacaggcgt agaatttatc gcagcaaaca cagatgtaca
   102541 agcattgagt agtacaaaag ctgagactgt tattcagttg ggacctaaat tgactcgtgg
   102601 tttgggtgca ggaggtcaac ctgaggttgg tcgtaaagcc gctgaagaaa gcgaagaaac
   102661 actgacggaa gctattagtg gtgccgatat ggtcttcatc actgctggta tgggaggagg
   102721 ctctggaact ggagctgctc ctgttattgc tcgtatcgcc aaagatttag gtgcgcttac
   102781 agttggtgtt gtaacacgtc cctttggttt tgaaggaagt aagcgtggac aatttgctgt
   102841 agaaggaatc aatcaacttc gtgagcatgt agacactcta ttgattatct caaacaacaa
   102901 tttgcttgaa attgttgata agaaaacacc gcttttggag gctcttagcg aagcggataa
   102961 cgttcttcgt caaggtgttc aagggattac cgatttgatt accaatccag gattgattaa
   103021 ccttgacttt gccgatgtga aaacggtaat ggcaaacaaa gggaatgctc ttatgggtat
   103081 tggtatcggt agtggagaag aacgtgtggt agaagcggca cgtaaggcaa tctattcacc
   103141 acttcttgaa acaactattg acggtgctga ggatgttatc gtcaacgtta ctggtggtct
   103201 tgacttaacc ttgattgagg cagaagaggc ttcacaaatt gtgaaccagg cagcaggtca
   103261 aggagtgaac atctggctcg gtacttcaat tgatgaaagt atgcgtgatg aaattcgtgt
   103321 aacagttgtt gcaacgggtg ttcgtcaaga ccgcgtagaa aaggttgtgg ctccacaagc
   103381 tagatctgct actaactacc gtgagacagt gaaaccagct cattcacatg gctttgatcg
   103441 tcattttgat atggcagaaa cagttgaatt gccaaaacaa aatccacgtc gtttggaacc
   103501 aactcaggta tctgcttttg gtgattggga tcttcgccgt gaatcgattg ttcgtacaac
   103561 agattcagtc gtttctccag tcgagcgctt tgaagcccca atttcacaag atgaagatga
   103621 attggataca cctccatttt tcaaaaatcg ttaagtaaat gaatgtaaaa gaaaatacag
   103681 aacttgtttt tcgagaagtt gcagaggcta gtctgagtgc tcatcgagag agtggttcgg
   103741 tctctgtcat tgcagttacc aagtatgtag atgtaccgac agcggaagcc ttgcttccgc
   103801 taggtgttca tcatatcggt gaaaatcgtg tagataagtt tctggaaaaa tatgaagctt
   103861 taaaagatcg agatgtgact tggcatttga ttggtacctt gcaaagacgt aaggtgaaag
   103921 atatcattca atacgttgat tatttccatg cattggactc agtaaagcta gcaggggaaa
   103981 ttcaaaaaag aagtgaccga gtcatcaagt gtttccttca agtaaatatt tctaaagaag
   104041 aaagcaaaca cggtttttcg agagaggaac tgctggaaat cttgccagag ttagccagac
   104101 tagataagat tgaatatgtt ggtttaatga cgatggcacc ttttgaggct agcagtgagc
   104161 agttgaaaga gattttcaag gcgacccaag atttacaaag agaaattcaa gagaaacaaa
   104221 ttccaaatat gcctatgacc gagttaagta tgggaatgag tcgtgattat aaagaagcga
   104281 ttcaattcgg ttccactttt gttcgtatag gtacatcatt ttttaagtag gagagaacca
   104341 tgtctttaaa agatagattc gatagattta tagattattt tacggaggat gaggattcaa
   104401 gtctccctta tgaaaaaaga gatgagcctg tgtttactcc agtaaattct tcacaggaac
   104461 cggctctccc aatgaatcaa ccttcacagt cggctggtac aaaagagaac aatatcacca
   104521 gacttcatgc aagacaacag gaattggcaa atcagagtca gcgtgcaacg gataaggtca
   104581 ttatagatgt tcgttatcct agaaaatatg aggatgcaac agaaattgtt gatttattgg
   104641 caggaaacga aagtatcttg attgattttc agtatatgac agaggtgcag gctcgtcgtt
   104701 gtttggacta tttggatgga gcttgtcatg ttttagctgg aaatttgaaa aaggtagctt
   104761 ctaccatgta tttgttgaca ccagtgaacg ttattgtaaa tgttgaagat atccgtttac
   104821 cagatgaaga tcaacagggt gagttcggtt ttgatatgaa gcgaaataga gtacgataat
   104881 gattttttta attcgtatga tttataatgc agtggatatt tactccctga ttttggtagc
   104941 cttcgctgtc atgtcttggt ttccaggtgc ctatgaatcc agtttaggtc gttggattgt
   105001 agcgttggta aaaccagtgc ttgctccctt gcaacgcctg cctttacaga tagcgggtct
   105061 tgatttatct gtttgggttg cgattgtttt ggttcgattt ttaggagaaa acctagtgcg
   105121 ttttctggcg atgataggat gaataaaggg atttatcagc atttctccat agaagatcgt
   105181 ccatttcttg acaagggaat ggaatggata aagaaggtag aagatagcta tgctcctttt
   105241 ttaactcctt ttatcaatcc tcatcaggag aagctattaa agattttggc caaaacctat
   105301 ggtcttgctt gtagcagtag tggggaattt gtctcgagtg agtatgttcg agttttatta
   105361 tacccagatt atttccaacc agagttttca gattttgaaa tatctcttca ggaaattgtg
   105421 tattccaata aatttgaaca tttaacgcat gctaagattt tagggacagt catcaatcaa
   105481 ttagggattg aacggaaact ttttggagat atcctagtag atgaagagcg ggcgcagatt
   105541 atgattaatc agcagtttct tcttctcttt caagatggat taaagaaaat tggtcgtata
   105601 cctgtttcgc tggaggaacg tcctctcgcc gagaaaatag ataagctaga acagtatcga
   105661 gaactggatt tatctgtgtc tagttttcga ttagatgttc ttttatcaaa tgttttgaaa
   105721 ctatctagga atcaagcaaa ccagttgatt gaaaagaaac ttgtccaagt aaattatcat
   105781 gtggtagaca aatcagatta tactgttcaa gttggagatt tgattagtgt gagaaaattt
   105841 ggtcgcttga aattacttca agataaggga caaacgaaaa aagagaagaa aaaaataacc
   105901 gtccagttat tattaagtaa gtgaggaata gaatgccaat tacatcatta gaaataaagg
   105961 acaaaacctt tggaactcga ttcagaggtt ttgatccaga agaagtcgat gaatttttag
   106021 atattgtggt tcgtgattac gaagatcttg ttcgtgcaaa tcatgataaa gatttgcgta
   106081 ttaagagttt agaagagcgt ttgtcttact ttgacgaaat gaaagattca ttgagccagt
   106141 ctgtattaat tgcccaggat acagcggaga gagtgaaaca ggcagcgcat gaacgttcaa
   106201 ataatatcat tcatcaagca gagcaagatg cccagcgctt gttggaagaa gctaagtaca
   106261 aggcaaacga gattcttcgt caagcaactg ataatgctaa gaaagttgct gttgaaacag
   106321 aagaattgaa gaacaagagc cgtgtcttcc accaacgtct caaatctaca attgagagtc
   106381 agttggctat tgttgaatct tcagattggg aagatattct tcgcccaaca gctatttatc
   106441 ttcaaaccag tgatgaagcc tttaaagaag tggttagcga ggtcttgggt gagtctgtgt
   106501 tacagcaaca tccagaggaa gaaccaattg atatgacacg tcagttctct caagtagaaa
   106561 tggcagaatt acaggctcgt attgaggcag ccaataaaga attggctgaa tttgaagctc
   106621 agactaaaca ggaagtggaa gctccaactc ctgtagtgag tcctcaaatt gaagaagaac
   106681 ctactcaacc agttggtcca atgtatgaag aaccagaagt agctccagta tatccttcag
   106741 cttcaacacc agctacagaa actgttgatt cagcaccagg atttgaagca ccgcaagaat
   106801 ctgttacaat tttataagaa atattctgag aacaatatct tatccttata tttccagcga
   106861 gcaggagatg gtgtgagtcc tgtaatccct aacgataaga ttatcctctc aaaaactcaa
   106921 gtctgaagtt agtaggattt gacgttcccc acgttacggg ataagaggga gaaagactag
   106981 atctttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt cgtggttttt
   107041 aatttgttat tatttataaa ggagatacca tgaaactcaa agataccctt aatcttggga
   107101 aaacagcttt tccaatgcgt gcaggccttc ctaccaaaga gccagtttgg caaaaggaat
   107161 gggaagatgc aaaactttat caacgtcgtc aagaactaaa tgaagggaaa ccgcattttg
   107221 tcttgcatga tggccctcca tacgcaaacg gaaatatcca cgttggacat gccatgaatc
   107281 atatctcaaa agatatcatc attcgttcta agtctatgtc aggttttaac tcaccttata
   107341 tcccgggttg ggatactcat ggtctgccaa tcgagcaagt tttggcaaag caaggtgtta
   107401 agcgcaaaga aatggacttg gttgagtact tgaaactttg tcgtgagtac gctctttctc
   107461 aagtttataa acaacgtgat gatttcaagc gcttggggat gtcaggtgac tgggaaaatt
   107521 tatatgtgac tttaactcca gactacgaag cagcccaaat ccgtgtattt ggtgagatgg
   107581 ctaataaagg ctatatctac cgtggtgcaa aaccagttta ctggtcttgg tcatctgagt
   107641 cagcccttgc tgaagcggaa attgaatacc atgatttggt ttcaacttcc ctttactatg
   107701 ccaataaggt aaaagatggc aaaggtgttc tagatacaga tacttatatc gttgtttgga
   107761 caactactcc atttactatt acagcttctc gtggtttgac tgttggtgca gatattgatt
   107821 acgttttggt tcaacctgct ggtgaaactc gtaagtttgt ggttgctgca gaattgttga
   107881 ttagcttgtc tgagaaattt ggttgggctg atgttcaagt gttggcaact taccgtggtc
   107941 aagaactcaa ccacatcgta acagaacacc catgggatac agttgtagat gagttggtta
   108001 tccttggtga ccacgttaca actgactctg gtactggtat tgtccataca gcccctggtt
   108061 ttggtgagga tgactacaat gttggtattg ctaatggtct tgaagtcgca gtgactgttg
   108121 acgaacgtgg tatcatgatg aagaatgctg gtcctgagtt tgaaggtcaa ttctatgaaa
   108181 aggtggttcc aactgttatt gaaaaacttg gtaacctcct tcttgctcaa gaagaaatct
   108241 ctcactcata cccatttgac tggcgtacca agaaaccaat tatctggcgt gcagtaccac
   108301 agtggttcgc ctctgtttca aaattccgcc aagaaatctt ggatgctatt gataaagtta
   108361 aattccatac agaatggggg aaagtacgtc tatataatat gattcgtgac cgtggtgact
   108421 gggttatctc tcgtcaacgt gcttggggtg ttccacttcc aatcttctat gcagaagacg
   108481 gtacagctat catgacagct gaaacgattg aacacgtagc tcaactcttt gaagtacatg
   108541 gttcaagcat ttggtgggaa cgtgatacca aagacctctt gccagaagga tttacacatc
   108601 caggttctcc aaatggggag ttcaagaaag aaacagatat tatggatgta tggtttgact
   108661 caggttcatc atggaatggt gttttggtaa atcgtccaaa tctgacttat ccagctgacc
   108721 tttaccttga aggttctgac caataccgtg gttggttcaa ctcatcactc attacatctg
   108781 ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt gcccttgatg
   108841 gtaaaggtga gaagatgtct aaatctcttg gaaataccat tgctccaagc gatgttgaaa
   108901 aacaatttgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca agcaacgacg
   108961 tacgtatctc tatggatatc ttgagccaag tctctgaaac ttaccgtaaa atccgtaaca
   109021 cccttcgttt cttgattgcc aatacatctg actttaaccc agctcaagac gcagtagcat
   109081 acgaagagct tcgctcagtt gataagtaca tgactattcg ctttaaccag cttgtcaaga
   109141 ccattcgtga tgcttacgca aactttgaat tcttgacaat ctacaaggcc ttggtgaact
   109201 ttatcaacgt tgacttgtca gccttttacc ttgattttgc taaggacgtt gtttacatcg
   109261 aaggtgctaa atcattggaa cgccgtcaaa tgcagactgt cttctatgac attcttgtga
   109321 aaatcacgaa actcttgact ccaatccttc ctcacactgc ggaagaaatc tggtcatatc
   109381 ttgagtttga agccgaagac ttcgttcaat tgtcagaatt gccagaagcg gaaacttttg
   109441 ctaatcaaga agaaatcttg gatacatggg cagccttcat ggacttccgt ggacaagctc
   109501 aaaaagcctt ggaagaagct cgtaatgcaa aagtaatcgg taaatcactt gaagcacact
   109561 tgacagttta tccaaacgaa gttgtgaaaa ctctactcga agcagtaaac agcaatgtgg
   109621 cccaactttt gatcgtgtct gagttgacca tggcagaggg accagctccg gaagctgccc
   109681 ttagcttcga agatgtagcc ttcacagttg aacgtgctgc tggtgaagta tgtgaccgtt
   109741 gccgtcgtat cgacccaaca acagcagaac gcagctacca ggcagttatc tgtgaccact
   109801 gtgcaagcat cgtagaagaa aattttgcgg aagcagtcgc aggaggattt gaagagaaat
   109861 aagatgaaaa gtctctatgc gtctagtata taaaaatgag ttattccaag tttataatct
   109921 ctcttgtgag atgctaaagt ttgatgagaa ttggttttgc taatattagg agaaagtaag
   109981 tatgctaaaa ttgcaagatt gtttttcttg cgattgttta aactagtgag gaaaaataaa
   110041 cattatgaga caaacaaatg ttagaggaag cttgtccctc cgtggcttta gaaaattaag
   110101 aactggtgca attgttgcga caggtgtgat tctactgggg ctgggctttt cagctccaac
   110161 tgcgtcagtc agtgaacaag atggtgtttg ggtagccaga acagttgcag aagtaaaagc
   110221 tgatattcaa aaagaaggtg atttatttaa gtatgtcatt aagtggggag atacattaag
   110281 tgttatcagc gaagcaagca atatccctgt agatgtactc caagaaatga atcaagcttc
   110341 aggcaagaat ttattcttac catacaatga attgtacttt actgaagctg aaacagtttc
   110401 agatacagtc acaaaacaca agattgtcat caaagaaagt ggtgcaagtg gcgaagttcg
   110461 cacttatgag gtcttgctca agaaagacca agaaacaaaa gctgttacct ttgaattaac
   110521 agatgtcact gagaaagttg aaaaaatgac tgtgaactat agcccagttt atcagcctgt
   110581 atcagtacca gtagtggaaa gagcggaaga atcagttgaa gagcctgccc tagtagcacc
   110641 agctgtgaca agcccagaag ttaaagaaga aacagaagat ccagtagtac taaaagcaga
   110701 agaagcagcg actaccccag caacgaaaga aacagcacca gaggtggtaa caccagctga
   110761 accaaacgca gaaaccccag cgccgaaagt agaagcgcca acagaatcat ctgaaccaaa
   110821 aggaacagag ccagaggtag ccaaaccagc tggagattca gtatcatcta caagtgagtc
   110881 aaatgaggat ggcaattcag gcgattcaac tcattcaaca ttgacctctg atgaaacaaa
   110941 accagaagag gtagaatcaa cttcagtaac ggacaatgtc ccttcaaatg cagggacaac
   111001 aaatcaacct ctaaccccaa catctaattc tgatgattca gcaccaaaag aagtagcaaa
   111061 tggaactgaa ggaaaagtag aagcgccgaa agttgaagaa gcagtatcag aaggagaaga
   111121 aggtaacgcc gaaataacaa ataatccatc aacaggcgct actccttcaa gtgatgaaac
   111181 gacagaacaa tctggaactc cagctccaaa accagaagag gaagctccag tagcgacaga
   111241 aacctcagcg gcatcagctg aatcaacaga atcagcacca gtggtagcaa aaccagctga
   111301 gccaaaagca gaaacaccag aagcaacaat tacaggagat gaaggaaaag aatctgaaga
   111361 atcaggaaca tctgcaactg tggaatcaac accagcagga gaagaaggaa aagcggagga
   111421 ttcagtttct tcaactgaat cttcatcaac tgcttctgaa ggggagtcaa cagctacgca
   111481 accagctgta gaagcaggaa cagattcaac atcggaagct gaagaacttg caactacgga
   111541 aacagcaaca acgccgaaaa cggaagagcc agaagcggta gccccagctc cagaagcacc
   111601 ctcagaatca gactcgaaag aagaagattc agctgcaggg gatacaacag ttacagaaga
   111661 acagccagct gcagaaactg tctctgaagg tggatcacca gctacgcaac cggctggaga
   111721 agaaggtaaa tctgaaaaag aaccgaaagt agaagggcaa ccatcaggta cagagtcggc
   111781 aaccccagaa cagcatacaa atattgagga aacaacagaa aagcaatcgg gggctacatc
   111841 agaaaattca ggtgatagtc tagtatcaga tgagccagct gcgagctcag gtatttcaac
   111901 atcttcagga acagaagggg cagaaacgat agatacagaa acaattgcag aaaaatcaga
   111961 aataccgtct ccagcagaag aaggatctgc taaagaagaa aaagaagtta ttaagaaact
   112021 agaacttaga aatatatctt ctgttgaact atattctaaa gaaggtgata agtatcgtca
   112081 tgtaacttca cttgctacct taccaagtaa tccagagact tactttatga aagttaaatc
   112141 agagaacttt aaagatgtta tgctaccagt tacaagcatt actaatgata ataaagataa
   112201 tagagatgtt tataaaatag tagcaagtgt aaagaatctg atacagcatg aaaataataa
   112261 agtactagag aattatacat actatttatc aaaaactcag caaggtgaaa ctggagtata
   112321 tacatcattt aaaaatttag ttgatgcgat gaatagagat tcttatggag agtttcgttt
   112381 aggtgcaact atggatgctc gtgaagttga acttccagat ggtcaagaaa gttatgtgaa
   112441 gaatgtattt cacggtagac taataggtca aaatagtaat aagtattatg ctatatataa
   112501 tttgaaaaag ccattattta atgctttaag taatgctaga gtacaaaatc tttcactaaa
   112561 agatgttaat atttccgcaa aggacgatac tgcaacacta gcgaaagaag caaataacaa
   112621 tactcatatt gataatgttc attctgatgg agcgatagcc ggggaacgta gcataggagg
   112681 attagtatca caagttaata attctactat ttctaatagt agctatactg gtagaataac
   112741 taatacatat aaaacagttg ctagttatca aatcggaggt ttagtaggta aactttctgg
   112801 tccgaatggt ttaattgata aatcgatagc atcaatagat ttggcttcaa acgcaacacg
   112861 aggtgatcag tctattggtg gaatagctgg ttcagtaatt gataatgcag tgataagtag
   112921 tagttatgct gaagggaaat taaataatgt tcaacctttt gcaaatgttg gtggagtagt
   112981 tggtgacctt tgggatccag taggcggatt ggaaaaatct ggtcaactat ctaatgtact
   113041 aagtgatgtt aatgttacaa acggtaatgc tatcgcgggt aaacattttg atcacatgaa
   113101 agcaactaat gtttatagta ataaaaataa taaggttgtg aacgtagtac aagaaaatga
   113161 tgaaatttta actaaggatt ctgttgttca aagaggagaa gtattagaag atgaacaaat
   113221 aaaagagaaa aaagctgctt ttgttactaa aaatactgtt aaaacagaag attttaattt
   113281 ctcttcaaga tatgtaactg actataaaaa tcttgagaat gctgattcgt caaaagaaaa
   113341 agtatataaa aatattgaaa aactattacc attttataat agcgaaacaa tagtgaagta
   113401 tgggaattta gtagagacaa gtagtaatct ttataataaa gaattattgt cagttgttcc
   113461 tatgaaagat aaagaagtaa ttagtgatat taataaaaat aaatcaagca taaataaatt
   113521 attactgtat tatgcggata attcgtatga gacattaaat gtaaattatc aaagtgattt
   113581 ttctaatgta gcagagtata gcataggcgg tacaaattta atttatacac cgaatacatt
   113641 acttcgcgat tacaataata tattagatgg agtattacct gtattagaaa ctgtggatta
   113701 taagtcagac gcaattagaa aagtattaga tgtttctaat gatgttagct taacggagtt
   113761 atatttagaa gaacaattca atactactaa aaataatttg agagatagtc taacaaaact
   113821 gcttactgca gatgctgcaa tatctgaaaa tagtaattca ataattgata attatgtaat
   113881 agaaaaaatt aagaataata aagaagcgtt acttctagga ttaacatatt tagagcgttg
   113941 gtacaatttc aaatatggtg aaacaaaagc gaaagattta gtgatgtacc acttggattt
   114001 ctttggtaaa tcaaatagtt cagctctaga taatgttatt gaactaggta aatctggatt
   114061 taataattta ttagctaaga ataatgttat tacttataat gtattgttat cgaaaaatta
   114121 taaaactaat aatttatttg atgcattaga aaaatataga aaagtttttg tgccagataa
   114181 aacaaataac gaatggttta aagaacaaac taaagcttat atagtggaag aaaaatctac
   114241 aattaaagag gtaaatgata aacaatcaaa agcaggtact ccgcaatcta taggggtgta
   114301 tgatagatta accagcccat cttggaaata cccaagtatg gtattgccgc tattaacatt
   114361 acctgaaaaa tcggtgttta tcatagcgaa catttcaaca ataggatttg gcgcttatga
   114421 tagatataga agtaaagaac atccagcagg aactaattta aatgactatg ttgaggcaaa
   114481 agctagagaa gcggctgtta gatttagaga tcactatgat tactggtata aaattctaga
   114541 taataataat aaagaaaaat tatatagaag tgtcctagtc tatgatgcat ttagattcgg
   114601 tgcagatgat aagggagaaa gagaaacaaa acaagctaat tttgaaactg atcatccagc
   114661 aataaaacac ttcttcggtc cagcaggaaa taatgttgtt cataattcta atggagcata
   114721 tgctacaggt gacgcattct actatatggc ttatcgtatg cttgataaag atggtgcggt
   114781 aacttataca catgaaatga cacataactc agatagagaa atttatcttg gaggctatgg
   114841 aagacgaaat ggacttggac cagagtttta tgcaaaagga ttgttacaag ctcctgatca
   114901 tcctgatgat cctactatta cgattaactc aatattgaaa tatgaagaat cagaagatcc
   114961 aactagactt caggtaaaag atcctacaaa acgatttaat aatgcagaag acttgcaaaa
   115021 atatatgtat aatatgtttg atgtaattta tatgctagaa tatctagaag gtaatgcagt
   115081 tgttaaatta gatatttcta agaaaaatga gttgttgaga aaaatagaaa ataaatttga
   115141 aacagatcca gatggaagta atgtctatgc aactaatgtt gttcgttatt taaaacctga
   115201 agagcttact aaattaactt catttaatag tttaattgaa aatgatgtta ttactagaag
   115261 aggatacgaa aatggaaatg acaatacttt taaacgaaat ggatattata caattaaact
   115321 attttcacca atatattcag ctttaagtaa taatgaagga actccgggag atttaatggg
   115381 tcgtcgtatg gcatttgaac tgttggctgc aaaaggattt aaagatggaa tggtaccata
   115441 tatttctaat caatatgcag aagaagcgaa agctaaaggt aaagtgatta agtcatatgg
   115501 taaggaagtt ggtaatgtaa ctgatgagtt agtacttcaa aaaatattta ataatcgtta
   115561 ctcatcttgg gtagaattta aaaaagcaat gtataatgaa agaatagcta aatttaaaaa
   115621 attaatgagc attagcttcg ataacccaaa tggaaattgg ttcagaaaag atagagtgac
   115681 aataaaaaat atagaagatc ttcaaagaat gataactact gctgtcaatg aagatgctga
   115741 ggattatctt gtgaacatat atccagaaag aagtagagtt cttaaactga aaaaagcaat
   115801 ctttaaagct tatcttgatc aaacaaatga ttttagaagt tcaatttttg atgaggaaaa
   115861 ataaatttac taattagggg tagcacatga agataggttt cgtttcttca tgtgtgaaac
   115921 tctttccttt ttggttttga ctagcttttt tgtgaaaaat tgtgtaaaat agaatagata
   115981 aacgagggga aacctcggaa aatttaaagg agaatccatc taatggtaaa attggttttt
   116041 gctcgccacg gtgagtctga atggaataaa gctaaccttt tcactggttg ggctgatgtt
   116101 gatttgtctg aaaaaggtac acaacaagcg attgacgctg gtaaattgat caaagaagct
   116161 ggtatcgaat ttgaccaagc ttacacctca gtattgaaac gtgcgattaa aacaacaaac
   116221 ttggctcttg aagcttctga ccaattgtgg gttccagttg aaaaatcatg gcgtttgaac
   116281 gaacgtcact acggtggttt gactggtaaa aacaaagctg aagctgctga gcaatttggt
   116341 gatgagcaag ttcacatctg gcgtcgttca tatgatgtat tgcctccaaa catggaccgt
   116401 gatgatgagc actcagctca cactgatcgt cgttacgctt cacttgacga ctcagttatc
   116461 ccagatgctg aaaacttgaa agtgactttg gaacgtgccc ttccattctg ggaagataaa
   116521 atcgctccag ctcttaaaga tggtaaaaac gtattcgtag gagctcacgg taactcaatc
   116581 cgtgctcttg taaaacacat caaaggtttg tcagatgacg agatcatgga cgtggaaatc
   116641 cctaacttcc caccattggt attcgaattc gacgaaaaat tgaacgtagt ttctgaatac
   116701 taccttggaa aataaaaaat tgtaagtcta gaattgattt ctaggctttt tatgtggctc
   116761 tttgtcaact gtagtgggtt gaagtcagat aagctcgaga aaggacaaat ttcgtccttt
   116821 cttttttgat gttcaaagcg atagaaatcc gttttttgaa gttttcaaag tttcgaaaac
   116881 caaaggcatt gcgcttgata agtttgatga gattattggt cgcttccagt ttggcattag
   116941 aatagtgtag ttgaagggcg ttgataatct tttctttatc tttgaggaag gttttaaaga
   117001 cagtctgaaa aataggatga acctgcttaa gattgtcctc aatgagtccg aaaaatttct
   117061 ctggttcctt attctggaag tgaaaaagca agagctgata gagctgatag tggtgtttca
   117121 agtcttccga ataactcaaa agcttgttta aaatctcttt attggttaag tgcatacgaa
   117181 aagtaggacg ataaaatcgc ttatcactca gtttacggc
//
LOCUS       DAVDHZ010000002       117045 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000002 DAVDHZ010000000
VERSION     DAVDHZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 117045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 117045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..117045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.002"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(102..845)
                     /locus_tag="VUR46_000106"
     CDS             complement(102..845)
                     /locus_tag="VUR46_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455615.1"
                     /translation="MSDIRDSLDKILAVSIDSIKDEQNFLNLVLSDSPEGNILKELAI
                     FKDNGALYKLIFSVYATFEYTIKECCNTALLTIDKNSLDSLTDELQMLTFRQKLDELR
                     KKIIEKREDNTVIKPLTDLHIKIKQQTEFNSNENMIDTKSNLNFNNFTEILEIFHFDK
                     KKYKSYSIIIDSIITYRNMIAHGNRKDLTEINIRQYIPGNYKIITLHKENNRLYFEDL
                     CSDMINLLKLFCQDLTDYVNEQKYLRQDK"
     gene            complement(838..1935)
                     /locus_tag="VUR46_000107"
     CDS             complement(838..1935)
                     /locus_tag="VUR46_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HET5455616.1"
                     /translation="MAQNKLVRRNFDISFNELYDMYNDGELVIKPEFQRLFRWSLTQQ
                     SLFIESLLLDMPIPPIYVDEQEDGRYVLVDGLQRISSYLNFRGITLDSPELTAIDPDD
                     DDCEIDFERVEPGFQLSGCEIIDDLNGKEFDELSIEEKRQLKRTFIRVEVLTKENPKE
                     IKYHMFKRLNSGGALLSKQELRNSNIRMIDEKFINFINELANSEDFVELTHYMTESDK
                     QQMKRAEVVLRFFLFKNKFINDNPDVRMGFLDDELTTYLEEVSSQKFPFEYETEKENF
                     LSLVSYLKNHFGSVIFSGISKNNTISKRFVQYNYDGFMQYFSKESNRDSSITIDKINE
                     IKNSDEYKQYRTGGLENSRKRVEVIAGKVNE"
     gene            complement(2030..4681)
                     /locus_tag="VUR46_000108"
     CDS             complement(2030..4681)
                     /locus_tag="VUR46_000108"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET5455617.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPELGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4674..5252)
                     /locus_tag="VUR46_000109"
     CDS             complement(4674..5252)
                     /locus_tag="VUR46_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5455618.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQDLLDNFHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQHQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5252..5812)
                     /locus_tag="VUR46_000110"
     CDS             complement(5252..5812)
                     /locus_tag="VUR46_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5455619.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDAQGNCCDDLRYGLLRSEWEVI"
     gene            complement(5799..6248)
                     /locus_tag="VUR46_000111"
     CDS             complement(5799..6248)
                     /locus_tag="VUR46_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET5455620.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6661..7056)
                     /locus_tag="VUR46_000112"
     CDS             complement(6661..7056)
                     /locus_tag="VUR46_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET5455621.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7152..7406)
                     /locus_tag="VUR46_000113"
     CDS             complement(7152..7406)
                     /locus_tag="VUR46_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET5455622.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(7416..8750)
                     /locus_tag="VUR46_000114"
     CDS             complement(7416..8750)
                     /locus_tag="VUR46_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET5455623.1"
                     /translation="MTDERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8750..8983)
                     /locus_tag="VUR46_000115"
     CDS             complement(8750..8983)
                     /locus_tag="VUR46_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET5455624.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9398..9580)
                     /locus_tag="VUR46_000116"
     CDS             complement(9398..9580)
                     /locus_tag="VUR46_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455625.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9582..10365)
                     /locus_tag="VUR46_000117"
                     /pseudo
     CDS             complement(9582..10365)
                     /locus_tag="VUR46_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10644..10994)
                     /gene="rbfA"
                     /locus_tag="VUR46_000118"
     CDS             complement(10644..10994)
                     /gene="rbfA"
                     /locus_tag="VUR46_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET5455626.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(11245..14037)
                     /gene="infB"
                     /locus_tag="VUR46_000119"
     CDS             complement(11245..14037)
                     /gene="infB"
                     /locus_tag="VUR46_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET5455627.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKSAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(14054..14353)
                     /locus_tag="VUR46_000120"
     CDS             complement(14054..14353)
                     /locus_tag="VUR46_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET5455628.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(14346..14639)
                     /locus_tag="VUR46_000121"
     CDS             complement(14346..14639)
                     /locus_tag="VUR46_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET5455629.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(14661..15797)
                     /gene="nusA"
                     /locus_tag="VUR46_000122"
     CDS             complement(14661..15797)
                     /gene="nusA"
                     /locus_tag="VUR46_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET5455630.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(15841..16320)
                     /gene="rimP"
                     /locus_tag="VUR46_000123"
     CDS             complement(15841..16320)
                     /gene="rimP"
                     /locus_tag="VUR46_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET5455631.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(16446..17081)
                     /gene="trmB"
                     /locus_tag="VUR46_000124"
     CDS             complement(16446..17081)
                     /gene="trmB"
                     /locus_tag="VUR46_000124"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET5455632.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(17078..17872)
                     /locus_tag="VUR46_000125"
     CDS             complement(17078..17872)
                     /locus_tag="VUR46_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET5455633.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(18034..18645)
                     /locus_tag="VUR46_000126"
     CDS             complement(18034..18645)
                     /locus_tag="VUR46_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5455634.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(18675..18923)
                     /locus_tag="VUR46_000127"
     CDS             complement(18675..18923)
                     /locus_tag="VUR46_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455635.1"
                     /translation="MYKHLFFLDSKTLDRLTPYIIVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLDLKNDV"
     gene            complement(18966..19655)
                     /locus_tag="VUR46_000128"
     CDS             complement(18966..19655)
                     /locus_tag="VUR46_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5455636.1"
                     /translation="MKKYQLVFKISAVLSYLFFVFGLSQLTLIVQNHWQFSSQVGNFF
                     WIRNILSLLFSGVMIWILVKTGHGYLFRIPRKKWLWYSILTVLVVVLHISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYVTLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(19687..19920)
                     /locus_tag="VUR46_000129"
     CDS             complement(19687..19920)
                     /locus_tag="VUR46_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HET5455637.1"
                     /translation="MDTKMMSQFAVMDNEMLARIEGGDVSDIYRGYANQVSPFGSYPP
                     ILKNSGPFPVSGYCPRGYHDRGYIGAGFHLCGI"
     gene            complement(20166..20624)
                     /locus_tag="VUR46_000130"
     CDS             complement(20166..20624)
                     /locus_tag="VUR46_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455638.1"
                     /translation="MKSSEETVTESVRDENTRSDSMNISDKVVSDSKGMSDKKRTEMK
                     ISNANSENSGKVESTNSTSEAKTTQSGNLAMLDNKNQLETLKPIFDAAQENKTSLTDV
                     KDADYVSESITSNEKLLLKTGEEESYQLIRLAVAFFMASIMIKVKQKIHK"
     gene            complement(20767..21192)
                     /locus_tag="VUR46_000131"
     CDS             complement(20767..21192)
                     /locus_tag="VUR46_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET5455639.1"
                     /translation="MKKQKIKSLLLVPLVFASITAGLAYAEEQPTTSSTQANDSSLVA
                     PDLPSAKEKVEHKPSVVTPEEYEKNVTDFKKIDIEAVRQSFTGDQLEHTIYFGRKTCS
                     HCRQFSPELKEFNNLIEKKLEYYDLDGKDFDGEAREFLF"
     gene            complement(21353..21757)
                     /locus_tag="VUR46_000132"
     CDS             complement(21353..21757)
                     /locus_tag="VUR46_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET5455640.1"
                     /translation="MKIFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSLVFQF
                     FLVVINLASILVTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAILCLTIMLLLIWGLKYYKK"
     gene            complement(21754..21918)
                     /locus_tag="VUR46_000133"
     CDS             complement(21754..21918)
                     /locus_tag="VUR46_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455641.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(22216..22335)
                     /locus_tag="VUR46_000134"
     CDS             complement(22216..22335)
                     /locus_tag="VUR46_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET5455642.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSPKKDTDSTP"
     gene            complement(22439..22588)
                     /gene="blpO"
                     /locus_tag="VUR46_000135"
     CDS             complement(22439..22588)
                     /gene="blpO"
                     /locus_tag="VUR46_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET5455643.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CVTTV"
     gene            complement(22832..23026)
                     /gene="blpN"
                     /locus_tag="VUR46_000136"
     CDS             complement(22832..23026)
                     /gene="blpN"
                     /locus_tag="VUR46_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET5455644.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGAVVCGYLAYTATS"
     gene            complement(23042..23296)
                     /gene="blpM"
                     /locus_tag="VUR46_000137"
     CDS             complement(23042..23296)
                     /gene="blpM"
                     /locus_tag="VUR46_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET5455645.1"
                     /translation="MNTKMMEQFEIMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            23577..25730
                     /gene="blpA"
                     /locus_tag="VUR46_000138"
     CDS             23577..25730
                     /gene="blpA"
                     /locus_tag="VUR46_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET5455646.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYILNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMDYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVFTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            25741..27102
                     /locus_tag="VUR46_000139"
     CDS             25741..27102
                     /locus_tag="VUR46_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET5455647.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSFVATKE
                     ITVTSQGEIAPTSAIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFRNFTKQSHDIELGISKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINKRARLPTGNPHQSILNRY
                     LVAAQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIIHLSSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHCITIIAQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            27159..27314
                     /gene="blpC"
                     /locus_tag="VUR46_000140"
     CDS             27159..27314
                     /gene="blpC"
                     /locus_tag="VUR46_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET5455648.1"
                     /translation="MDKNQNLTSFQELTTTELNQITGGGWWKDLLHRFNVIEQNNTKG
                     FNQPIQL"
     gene            complement(27356..28696)
                     /locus_tag="VUR46_000141"
     CDS             complement(27356..28696)
                     /locus_tag="VUR46_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5455649.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKN
                     KLHERLNQEQTLRYRDMERHSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDSVLKDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFLKARDKKIIFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIHTE"
     gene            complement(28710..29448)
                     /locus_tag="VUR46_000142"
                     /pseudo
     CDS             complement(28710..29448)
                     /locus_tag="VUR46_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(29453..29791)
                     /locus_tag="VUR46_000143"
     CDS             complement(29453..29791)
                     /locus_tag="VUR46_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5455650.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQKRILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            30047..30376
                     /locus_tag="VUR46_000144"
     CDS             30047..30376
                     /locus_tag="VUR46_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET5455651.1"
                     /translation="MTDTDPIKRAQALITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETADNRVLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLSL
                     YGPTIIL"
     gene            complement(30437..31486)
                     /locus_tag="VUR46_000145"
     CDS             complement(30437..31486)
                     /locus_tag="VUR46_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5455652.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLAMGYGLPVFLVYVLLLGVGKYFLFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKVVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSLLAQVFIEQSWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQAVVRGLTSLVLVVELVVGLVTFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(31483..32214)
                     /locus_tag="VUR46_000146"
     CDS             complement(31483..32214)
                     /locus_tag="VUR46_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455653.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYKELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            32282..32692
                     /locus_tag="VUR46_000147"
     CDS             32282..32692
                     /locus_tag="VUR46_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET5455654.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            32702..32989
                     /locus_tag="VUR46_000148"
     CDS             32702..32989
                     /locus_tag="VUR46_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455655.1"
                     /translation="MKLSNLLLFAGATAGSYLVTKNRQTITDEILNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKILEKDIQTRLAVIKEMQGTEDK"
     gene            33150..33389
                     /locus_tag="VUR46_000149"
     CDS             33150..33389
                     /locus_tag="VUR46_000149"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455656.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDKVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYHSPFHN"
     gene            complement(33715..34851)
                     /gene="dnaJ"
                     /locus_tag="VUR46_000150"
     CDS             complement(33715..34851)
                     /gene="dnaJ"
                     /locus_tag="VUR46_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET5455657.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(35195..35599)
                     /locus_tag="VUR46_000151"
     CDS             complement(35195..35599)
                     /locus_tag="VUR46_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HET5455658.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGVIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(35610..37433)
                     /gene="dnaK"
                     /locus_tag="VUR46_000152"
     CDS             complement(35610..37433)
                     /gene="dnaK"
                     /locus_tag="VUR46_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET5455659.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNSDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVIAGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQETGNAGDDVVDGEFTEK"
     gene            complement(37913..38437)
                     /gene="grpE"
                     /locus_tag="VUR46_000153"
     CDS             complement(37913..38437)
                     /gene="grpE"
                     /locus_tag="VUR46_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET5455660.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(38464..39498)
                     /gene="hrcA"
                     /locus_tag="VUR46_000154"
     CDS             complement(38464..39498)
                     /gene="hrcA"
                     /locus_tag="VUR46_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET5455661.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKAIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVVAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYL
                     YLSSNHYEVH"
     gene            complement(39662..40171)
                     /locus_tag="VUR46_000155"
     CDS             complement(39662..40171)
                     /locus_tag="VUR46_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET5455662.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSCFGLFYFEQ
                     GQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCMSSFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            40779..43112
                     /locus_tag="VUR46_000156"
     CDS             40779..43112
                     /locus_tag="VUR46_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET5455663.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKSGEHITYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIGD
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVGEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLDKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            43125..44588
                     /locus_tag="VUR46_000157"
     CDS             43125..44588
                     /locus_tag="VUR46_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET5455664.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERAALNHKIDNVLADILQLLEDK"
     gene            44588..46135
                     /locus_tag="VUR46_000158"
     CDS             44588..46135
                     /locus_tag="VUR46_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5455665.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALSPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYA
                     MQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLEISIVSKEDDNSYYGNIP
                     MNWVVIKIKDIFSINTGLSYKKGDLSINNKGIRIIRGGNIKPLEFSLLDNDYYIDTQF
                     ISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIFQLTPFESSEIISKF
                     LLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFEEQELITQKIEKLFE
                     KVNQLWK"
     gene            complement(46083..46691)
                     /locus_tag="VUR46_000159"
     CDS             complement(46083..46691)
                     /locus_tag="VUR46_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5455666.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETSSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQFFE"
     gene            complement(46702..47499)
                     /gene="psrA"
                     /locus_tag="VUR46_000160"
     CDS             complement(46702..47499)
                     /gene="psrA"
                     /locus_tag="VUR46_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET5455667.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLTFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            complement(47556..48875)
                     /locus_tag="VUR46_000161"
     CDS             complement(47556..48875)
                     /locus_tag="VUR46_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5455668.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDSSYYEEVPCEIPESWEWVRLNDITSYI
                     QRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNS
                     TGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEE
                     KASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            49420..49539
                     /locus_tag="VUR46_000162"
     CDS             49420..49539
                     /locus_tag="VUR46_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET5455669.1"
                     /translation="MPDIVFKIEFFHSDSLIFFYTSDDKSNLQKSQEDFSKNK"
     gene            complement(49635..50981)
                     /gene="glnA"
                     /locus_tag="VUR46_000163"
     CDS             complement(49635..50981)
                     /gene="glnA"
                     /locus_tag="VUR46_000163"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET5455670.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKAMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLHGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVRAALGEHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(51018..51374)
                     /gene="glnR"
                     /locus_tag="VUR46_000164"
     CDS             complement(51018..51374)
                     /gene="glnR"
                     /locus_tag="VUR46_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET5455671.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(51451..51978)
                     /locus_tag="VUR46_000165"
     CDS             complement(51451..51978)
                     /locus_tag="VUR46_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET5455672.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(52114..53310)
                     /locus_tag="VUR46_000166"
     CDS             complement(52114..53310)
                     /locus_tag="VUR46_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET5455673.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELET
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TVGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(53400..58275)
                     /locus_tag="VUR46_000167"
                     /pseudo
     CDS             complement(53400..58275)
                     /locus_tag="VUR46_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            58564..60194
                     /locus_tag="VUR46_000168"
                     /pseudo
     CDS             58564..60194
                     /locus_tag="VUR46_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            complement(60753..62360)
                     /locus_tag="VUR46_000169"
     CDS             complement(60753..62360)
                     /locus_tag="VUR46_000169"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET5455674.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKIFLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(62750..63337)
                     /locus_tag="VUR46_000170"
     CDS             complement(62750..63337)
                     /locus_tag="VUR46_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET5455675.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(63465..63914)
                     /locus_tag="VUR46_000171"
     CDS             complement(63465..63914)
                     /locus_tag="VUR46_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5455676.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(63919..64308)
                     /locus_tag="VUR46_000172"
     CDS             complement(63919..64308)
                     /locus_tag="VUR46_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET5455677.1"
                     /translation="MKVNIVDLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(64336..64986)
                     /locus_tag="VUR46_000173"
     CDS             complement(64336..64986)
                     /locus_tag="VUR46_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET5455678.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(64976..65539)
                     /locus_tag="VUR46_000174"
     CDS             complement(64976..65539)
                     /locus_tag="VUR46_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5455679.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(65704..65922)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(65976..66479)
                     /locus_tag="VUR46_000175"
     CDS             complement(65976..66479)
                     /locus_tag="VUR46_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET5455680.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSRMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(66672..67502)
                     /locus_tag="VUR46_000176"
     CDS             complement(66672..67502)
                     /locus_tag="VUR46_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET5455681.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLILQNQGRFYNPWK
                     "
     gene            complement(67487..69169)
                     /locus_tag="VUR46_000177"
     CDS             complement(67487..69169)
                     /locus_tag="VUR46_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455682.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLSLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(69271..69528)
                     /locus_tag="VUR46_000178"
     CDS             complement(69271..69528)
                     /locus_tag="VUR46_000178"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455683.1"
                     /translation="MKIKEKTRKQVAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(69535..70083)
                     /locus_tag="VUR46_000179"
     CDS             complement(69535..70083)
                     /locus_tag="VUR46_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET5455684.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(70098..70946)
                     /locus_tag="VUR46_000180"
     CDS             complement(70098..70946)
                     /locus_tag="VUR46_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET5455685.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQLVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            71135..72484
                     /gene="trkA"
                     /locus_tag="VUR46_000181"
     CDS             71135..72484
                     /gene="trkA"
                     /locus_tag="VUR46_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET5455686.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGGDFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            72488..73927
                     /locus_tag="VUR46_000182"
     CDS             72488..73927
                     /locus_tag="VUR46_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET5455687.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLITLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            74013..74813
                     /locus_tag="VUR46_000183"
                     /pseudo
     CDS             74013..74813
                     /locus_tag="VUR46_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            75686..75865
                     /locus_tag="VUR46_000184"
     CDS             75686..75865
                     /locus_tag="VUR46_000184"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5455688.1"
                     /translation="MKTVTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVRE
                     YITDSISTNTIEEAR"
     gene            76476..76760
                     /locus_tag="VUR46_000185"
     CDS             76476..76760
                     /locus_tag="VUR46_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455689.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVKKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            76753..77001
                     /locus_tag="VUR46_000186"
     CDS             76753..77001
                     /locus_tag="VUR46_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455690.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLPATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVAKQI"
     gene            77097..77315
                     /locus_tag="VUR46_000187"
     CDS             77097..77315
                     /locus_tag="VUR46_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455691.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDAFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(77598..79922)
                     /gene="pflB"
                     /locus_tag="VUR46_000188"
     CDS             complement(77598..79922)
                     /gene="pflB"
                     /locus_tag="VUR46_000188"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET5455692.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGSTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            80270..81331
                     /gene="dinB"
                     /locus_tag="VUR46_000189"
     CDS             80270..81331
                     /gene="dinB"
                     /locus_tag="VUR46_000189"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET5455693.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIELMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVVLNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(81478..82323)
                     /locus_tag="VUR46_000190"
     CDS             complement(81478..82323)
                     /locus_tag="VUR46_000190"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET5455694.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(82354..82491)
                     /locus_tag="VUR46_000191"
     CDS             complement(82354..82491)
                     /locus_tag="VUR46_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455695.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            82578..83519
                     /locus_tag="VUR46_000192"
     CDS             82578..83519
                     /locus_tag="VUR46_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET5455696.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYEVYTYTPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKVEKCVNDLMAEFNSVITTVTGIDNRLGAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLR"
     gene            complement(83898..85787)
                     /locus_tag="VUR46_000193"
     CDS             complement(83898..85787)
                     /locus_tag="VUR46_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET5455697.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGAELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLHLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGGEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVLYYWKLQLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINFYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            85926..87491
                     /locus_tag="VUR46_000194"
     CDS             85926..87491
                     /locus_tag="VUR46_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET5455698.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMGKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILHFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            87491..88231
                     /locus_tag="VUR46_000195"
     CDS             87491..88231
                     /locus_tag="VUR46_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5455699.1"
                     /translation="MTQVILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(88340..88555)
                     /locus_tag="VUR46_000196"
     CDS             complement(88340..88555)
                     /locus_tag="VUR46_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455700.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(89426..90676)
                     /gene="ilvA"
                     /locus_tag="VUR46_000197"
     CDS             complement(89426..90676)
                     /gene="ilvA"
                     /locus_tag="VUR46_000197"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET5455701.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGISTYIKETSPEIEIIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHVQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(90726..90866)
                     /locus_tag="VUR46_000198"
                     /pseudo
     CDS             complement(90726..90866)
                     /locus_tag="VUR46_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
     gene            complement(91051..91287)
                     /locus_tag="VUR46_000199"
     CDS             complement(91051..91287)
                     /locus_tag="VUR46_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455702.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(91394..92416)
                     /gene="ilvC"
                     /locus_tag="VUR46_000200"
     CDS             complement(91394..92416)
                     /gene="ilvC"
                     /locus_tag="VUR46_000200"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET5455703.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYIVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGLRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(92482..92958)
                     /gene="ilvN"
                     /locus_tag="VUR46_000201"
     CDS             complement(92482..92958)
                     /gene="ilvN"
                     /locus_tag="VUR46_000201"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET5455704.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(92951..94651)
                     /locus_tag="VUR46_000202"
     CDS             complement(92951..94651)
                     /locus_tag="VUR46_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET5455705.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(94851..96518)
                     /locus_tag="VUR46_000203"
     CDS             complement(94851..96518)
                     /locus_tag="VUR46_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET5455706.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(96521..96886)
                     /locus_tag="VUR46_000204"
     CDS             complement(96521..96886)
                     /locus_tag="VUR46_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5455707.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(97043..97231)
                     /locus_tag="VUR46_000205"
     CDS             complement(97043..97231)
                     /locus_tag="VUR46_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET5455708.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(97347..97523)
                     /locus_tag="VUR46_000206"
     CDS             complement(97347..97523)
                     /locus_tag="VUR46_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET5455709.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(97634..97831)
                     /locus_tag="VUR46_000207"
     CDS             complement(97634..97831)
                     /locus_tag="VUR46_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET5455710.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(98246..99790)
                     /locus_tag="VUR46_000208"
     CDS             complement(98246..99790)
                     /locus_tag="VUR46_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET5455711.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYDQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            100003..100305
                     /gene="gatC"
                     /locus_tag="VUR46_000209"
     CDS             100003..100305
                     /gene="gatC"
                     /locus_tag="VUR46_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET5455712.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            100305..101771
                     /gene="gatA"
                     /locus_tag="VUR46_000210"
     CDS             100305..101771
                     /gene="gatA"
                     /locus_tag="VUR46_000210"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET5455713.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGFPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            101771..103213
                     /gene="gatB"
                     /locus_tag="VUR46_000211"
     CDS             101771..103213
                     /gene="gatB"
                     /locus_tag="VUR46_000211"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET5455714.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMQTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            103337..104380
                     /locus_tag="VUR46_000212"
     CDS             103337..104380
                     /locus_tag="VUR46_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET5455715.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTCVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            104711..105271
                     /gene="efp"
                     /locus_tag="VUR46_000213"
     CDS             104711..105271
                     /gene="efp"
                     /locus_tag="VUR46_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET5455716.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            105293..105682
                     /locus_tag="VUR46_000214"
     CDS             105293..105682
                     /locus_tag="VUR46_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5455717.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            105675..106097
                     /gene="nusB"
                     /locus_tag="VUR46_000215"
     CDS             105675..106097
                     /gene="nusB"
                     /locus_tag="VUR46_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET5455718.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVAEEQ"
     gene            complement(106146..106373)
                     /locus_tag="VUR46_000216"
     CDS             complement(106146..106373)
                     /locus_tag="VUR46_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5455719.1"
                     /translation="MLSGLIFGLSHLILSHRDPISLLYYSLIGFFFAFVYRSTDNLRL
                     TILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(106395..106786)
                     /locus_tag="VUR46_000217"
                     /pseudo
     CDS             complement(106395..106786)
                     /locus_tag="VUR46_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835936.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(106892..107077)
                     /gene="briC"
                     /locus_tag="VUR46_000218"
     CDS             complement(106892..107077)
                     /gene="briC"
                     /locus_tag="VUR46_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET5455720.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(107236..108003)
                     /locus_tag="VUR46_000219"
     CDS             complement(107236..108003)
                     /locus_tag="VUR46_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET5455721.1"
                     /translation="MNIAKIVREAREQSHLTTLDFATGIFDDFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLRVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGSRAMEAAELMKITSHELLEMDVVDKVISETGLSS
                     KELIKNVKKELQTELARLSQKSLEELLEERYQRFRKY"
     gene            complement(108000..108866)
                     /locus_tag="VUR46_000220"
     CDS             complement(108000..108866)
                     /locus_tag="VUR46_000220"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET5455722.1"
                     /translation="MALFSKKDKYIRINPNRSIREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLVLTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     TMREKTGLDEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEQL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(108903..110270)
                     /gene="accC"
                     /locus_tag="VUR46_000221"
     CDS             complement(108903..110270)
                     /gene="accC"
                     /locus_tag="VUR46_000221"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET5455723.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKTEDLVFAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAESVGYENAGTIEF
                     LLDEASGNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQIRIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(110282..110704)
                     /gene="fabZ"
                     /locus_tag="VUR46_000222"
     CDS             complement(110282..110704)
                     /gene="fabZ"
                     /locus_tag="VUR46_000222"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET5455724.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(110701..111186)
                     /locus_tag="VUR46_000223"
     CDS             complement(110701..111186)
                     /locus_tag="VUR46_000223"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET5455725.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(111189..112424)
                     /gene="fabF"
                     /locus_tag="VUR46_000224"
     CDS             complement(111189..112424)
                     /gene="fabF"
                     /locus_tag="VUR46_000224"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET5455726.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(112446..113177)
                     /gene="fabG"
                     /locus_tag="VUR46_000225"
     CDS             complement(112446..113177)
                     /gene="fabG"
                     /locus_tag="VUR46_000225"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET5455727.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGVISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(113211..114131)
                     /gene="fabD"
                     /locus_tag="VUR46_000226"
     CDS             complement(113211..114131)
                     /gene="fabD"
                     /locus_tag="VUR46_000226"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET5455728.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVSSGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(114124..115098)
                     /gene="fabK"
                     /locus_tag="VUR46_000227"
     CDS             complement(114124..115098)
                     /gene="fabK"
                     /locus_tag="VUR46_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET5455729.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(115217..115441)
                     /locus_tag="VUR46_000228"
     CDS             complement(115217..115441)
                     /locus_tag="VUR46_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET5455730.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(115501..116475)
                     /locus_tag="VUR46_000229"
     CDS             complement(115501..116475)
                     /locus_tag="VUR46_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET5455731.1"
                     /translation="MAFSKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGIIGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(116475..116909)
                     /locus_tag="VUR46_000230"
     CDS             complement(116475..116909)
                     /locus_tag="VUR46_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5455732.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
BASE COUNT        35166 a        25331 c        21208 g        35340 t
ORIGIN      
        1 aaaacacggc attacaccat gtttctatgt tattctataa agataatatt cttagtttaa
       61 cttttagaat gtcgttcttt tttaattatt taaaataata ttcacttatc ttgacgtaaa
      121 tacttttgtt cgtttacata atctgtaaga tcctgacaaa atagtttaag aagattaatc
      181 atatcactac ataaatcttc aaaataaagt cgattatttt ctttatgaag agtaataatt
      241 ttataatttc caggaatata ttgtctaatg tttatctccg ttaaatcctt tctgtttcca
      301 tgagcaatca tatttcgata agttattatt gaatcaatga taattgaata ggatttatat
      361 ttctttttat caaaatgaaa tatttcaaga atttctgtaa aattattgaa attcagattt
      421 gatttcgtat caatcatatt ttcattgcta ttgaattcgg tttgttgttt aattttgata
      481 tgcaagtccg taagtggttt aataactgtg ttatcttctc tcttctcaat tatttttttg
      541 cgtaattcat ctagcttttg tcgaaaagtt agcatttgta gttcatctgt caatgaatct
      601 agactatttt tatcgattgt tagtaaggca gtattacagc attccttgat ggtatactca
      661 aaggtagcat agactgaaaa tatcaattta tataatgctc cattatcctt aaagattgct
      721 agttctttta gaatattacc ctcaggagag tcggataata ctaaatttaa aaaattctgt
      781 tcatctttaa tactatcgat tgaaactgct aaaattttgt caagagaatc cctaatatca
      841 ctcatttact ttccctgcta ttacctcaac gcgttttcta gaattttcaa gccccccagt
      901 tcggtattgc ttatactcat cactattttt tatctcatta atcttatcaa tagtaattga
      961 tgaatctcta ttgctctctt ttgagaaata ttgcataaaa ccgtcgtagt tatactggac
     1021 aaatctttta gaaatagtat tgtttttgct gataccactg aaaataacac taccaaaatg
     1081 atttttaaga tacgaaacta aactcaaaaa gttttccttt tctgtttcat attcaaaagg
     1141 aaacttctgt gaggaaactt cttctaaata ggtcgtaagt tcatcatcta aaaatcccat
     1201 tcttacatcg ggattatcat taataaattt atttttaaac aagaagaatc ttaaaacaac
     1261 ttcagctctc ttcatttgct gcttatcaga ttctgtcatg taatgtgtca attcaacaaa
     1321 atcttcagag ttagccagtt cattaataaa gtttatgaac ttctcgtcaa tcatgcgtat
     1381 attactgttt cttaattctt gtttagatag caatgctcca ccagaattta atcttttaaa
     1441 catatgatat ttaatttctt ttggattttc ttttgttaag acttctactc gaataaacgt
     1501 acgttttaat tgccgttttt cctctatgct taactcgtca aattctttac cattcaaatc
     1561 atcaataatt tcacaacctg ataattgaaa acctggttca actcgctcaa agtctatctc
     1621 gcagtcatca tcatctggat caatagcagt taattctgga gaatctaacg ttatgcctct
     1681 gaaatttaga taagatgaaa ttctttgtag tccatctact agaacatacc tcccatcttc
     1741 ttgctcatct acataaatag gaggtatagg catatctaaa agaagggact caataaagag
     1801 agattgctgt gttaatgacc atctaaataa tctttggaat tctggcttaa taactaattc
     1861 gccatcatta tacatatcat aaagttcatt aaacgatata tcaaaatttc ttctgacaag
     1921 tttattttgt gccataaaaa agtctcaact ttcaataaat atttataata ttgattatac
     1981 cataaaaaca cagtttttac actgtgtttt attaaattta tataattgtt tatttcacca
     2041 acttcttcat ctcatcaata cgtgctacgg tcgcatcata cttggcttgg tagtcagctt
     2101 gtttgtcacg ttctttttgg acgacttctg gtttggcgtt ggctacgaag cgttcgttag
     2161 agagtttctt accaaccatg tccagttctt tttgccattt agcgagttct ttgtcgagac
     2221 gagctagttc ttcttcaaca ttgaggagat cggccagtgg caggtagatt tctgctcctg
     2281 tgatgacact tgacatagcc agttcaggtg cagggatggt tgatgcgatt tccaaatgtt
     2341 ctggatttgt aaagcgtttg atgtagttga cattgctgtt aaagaaggct tccaagtcac
     2401 tatcgctagt cttaacaagg attgtgatag gtttgcttgg tgctacattt acttccgcac
     2461 gcgcattacg aacggcacgg atcaagtctt tgagactttc cacaccagtg tgggcagcaa
     2521 ggtcttcaaa ggctagatta acagttgggt atgcagctgt cacgatagaa ccttctgaga
     2581 tttgtccaaa gatttcctct gtcacgaatg gcatgattgg gtgaaggaga cgaaggatct
     2641 tgtccagcgt atagaggaga acagatcgag taatgacctt atcgtcttca ttgtcgctgt
     2701 atagaacttc cttggtcaac tcaacatacc agttggcaaa ttcttcccag atgaagttgt
     2761 aaaggatatg accagccaca ccaaactcga acttatcaaa gttttcagta acttttgcaa
     2821 tggtttcgtt gagattgtgg agaatccagc ggtccgtcac attaccagcc tcacctgttg
     2881 caacttttgt gacattgtca tgcgccacat ccagcgtcaa accttcattg ttcatgagga
     2941 tatagcgaga aatgttccaa attttgttaa taaagttcca tgaagcatcc attttctcgt
     3001 aagagaaacg aacgtcttga cctggtgcgg aaccgtttga aaggaaccaa cgaagggcat
     3061 cagcaccgta tttctcgatg acatccattg ggtcaatccc gttaccgaga gatttagaca
     3121 tcttgcgtcc ttgctcgtca cggatgagac cgtggataag cacgttttgg aatggctgac
     3181 gaccagtaaa ttccaaggac tggaagatca tacgagacac ccagaagaag atgatgtcgt
     3241 aacctgttac caaggttgaa gttgggaaat aacgtttaaa gtcttctgag tcgacttcag
     3301 gccagcccat ggttgaaaat ggccagaggg cagaactgaa ccaagtatcc aagacgtctt
     3361 cgtcctgagt ccatccgtca ccttctggag cttcttcgcc gacatacatt tcaccatcag
     3421 cattgtacca ggcagggatt tggtgacccc accaaagctg acgagagata acccagtcgt
     3481 ggacattttc catccattga aggaaggtat cgttgaaacg aggtgggtag aattcgacct
     3541 tgtcctctgt gtcttggttg gcaatggcgt tcttagccaa ttggtccatc ttgacgaacc
     3601 attgagtaga caagcgtggc tcaactacga cacctgtacg ttctgagtga ccaacactgt
     3661 ggacacgttt ttcgattttg acaagggcac cgatttcttc caacttagca acgactgcct
     3721 tacgagcttc aaaacgatcc atgcctgaaa attcaaaggc aagctcattc atagttccgt
     3781 cgtcgttcat gacgttgact tgtggcaagt tatgacgttg gccaaccaag aagtcatttg
     3841 gatcgtgggc aggtgtgatt ttcacgacac ctgtaccaag ctcaggatct gcgtgctcat
     3901 ctccaacgat tgggatgagt ttattagcga ttggaaggat gacgttttta ccaatcaagt
     3961 ccttgtagcg cgggtcttct ggattaaccg caaccgcaac gtccccaaac atagtctcag
     4021 gacgagttgt agcaacttca agggcgcgtg aaccatcttc cagcatgtaa ttcatgtggt
     4081 agaaggcacc ttctacatcc ttgtgaatca cctcaatatc agaaagggct gtgcgagctg
     4141 ctgggtccca gttgatgata aactcaccac gatagatcca gcctttcttg taaagatcca
     4201 caaagacctt acgaacagct tttgacaaac cttcatcaag agtgaaacgc tcacgagaat
     4261 agtctacaga aagccccatc ttgccccatt gttccttgat ggtagtggca tattcgtctt
     4321 tccattccca gaccttcgtc aagaaagact cacgacctag gtcataacgc gtaataccct
     4381 caccacgtaa gcgctcctca accttagcct gagtcgcaat accagcgtgg tccatacctg
     4441 gaagccaaag ggtatcaaag ccttgcatgc gtttttgacg gatgatgata tcctgcaaag
     4501 tcgtatccca agcgtgacca aggtgaagtt tcccagttac gtttggtggt ggaatcacga
     4561 ttgaataagg cttagccttt tgatcgcctg aaggcttgaa aacatccgca tcaagccatt
     4621 tttggtaacg accagcctca acctcggctg gattgtattt aggtgaaagt tctttagaca
     4681 tgtgtgtgtc ctttctctat tttgtttatt ttattttgaa tttgcttagc agcttcttct
     4741 gcagacaaat tcgtattatt tattttaaag tagtggtgca actcattcgg ttgatgttgg
     4801 gaatttaatt gaagtgtttc agcggtctct aaaatttctc tttcagatac ctcaatatgt
     4861 cgttttaagg gtttgtgctt taatcgattc tccgttcgat ttcgacgtat gcactcttca
     4921 agacttgttt ccaattcaac aaacagaatc tcttgatgaa agttatccaa taaatcctga
     4981 atttgcttta aatacatcag ctggtactga tttgaaaaat caattacgtc tgttaaaatt
     5041 actgatcgct gatttcttgc acttgctcca aggaaagaaa aggtaattcc acgaacaaat
     5101 tcccacatct cctcggtata atcctgatag atctctagtg caaaatcaat ggcttgatgg
     5161 ttataaaata gggtagcatc cgtcagtcga gataattctt gaccaatggt catttttcct
     5221 gatgctggag caccaatgat gaaaagatgc atcaaatcac ctcccactca ctcctcagca
     5281 agccatatct caaatcatca cagcagttgc cttgagcatc tttgcggtct cttatgcgag
     5341 cttcgagggt aaagccaagc ttttccgaga ctcgttgact ttgaaggtta tatccaaagc
     5401 aagttagttc aatcttgtga agaccaagtt ctttaaaagc tagatcaatc aaggcacacg
     5461 ctgcttctgg aacataacct cgcccccaat agtctgggtg taaggtatag ccgatttcca
     5521 gcacatcatc ttcatggcga tggttgaaat cgacagagcc aacgatctta tccgttcctt
     5581 tgacgacaat cccgtagcct gctgggagat tttccttttg attacgctcc ggaagaatgt
     5641 gctccagata ataaatctca tcttccaagg tcttgactgg aggaaaacct gctggatagg
     5701 caacctctgg caaactagca tagtcaaaga tatcctcagc atccgccaca gtacggactc
     5761 gtaaaacgag acgttctgtt tcgattttat ctggcagctc agttcttgcc atccttcttc
     5821 ctcgcttttt tgatgaaact gcccttcata tctacacgct tgtccagata gcgataaacg
     5881 cgctgatatc catctcccat gaaataggtt ggggcaaaca gttgattttt aaaatgtccc
     5941 ttttcatcca ggagttctgg aacaacaagt cgctcaagaa tcttggcaaa gatgtggcaa
     6001 ataccgtctt cctcaacaat cctatctacc cgacaatcta aaacaagtgg acaggcgtct
     6061 aaaataggag tctgagttcg ttcagaaatt tcataatgca ctcccaaacg ttccaatttc
     6121 tcctgatgac tgataaaacc agcctgctcc atcgcaagca tagaagtttc atcagaaata
     6181 ttcacagtaa atttttgata ctgtttgatc tgctctgcgg cattctctct cgcaacgact
     6241 ccaatcacaa cccaatctcc tagactataa gaggaactac aggtcgtgat gttatagcca
     6301 aaattctaat cttgatatcc taaaataaaa acaggaaaac cataatatag tttacttgtg
     6361 ttaaaagatt gcttcataac aacccccttt gactaagacg taaaagaaaa gccctgccat
     6421 ctacatgaca gggacgaatg tgtttatccg cggtaccacc caatttcggg cagttgcccg
     6481 caactctcgt ctttaaagca aaaagacact tttatttcaa tttttcatcc attagcaacc
     6541 agttttgaca catttgtgga cttctcagcg ccgccacttt ctgtaaaatg tgggattcaa
     6601 aacacctcta atggctctat tgtagcaaga ttttttcgga aatgcaaggc tcaagaaaaa
     6661 ttacttgaac ttgatgccat tttctttcaa tttcttgatg gtagctgggc cgattccttt
     6721 caaggcaagg agttcttttt cagtccagtt tttgaaatct gaagcagact tgattccttc
     6781 atcatagaaa gtcttggcac gatcaagtgg aagtccaccc aaatttgctg caaaatcttc
     6841 tacagaatta gctacttttt gagcttgctc tttggtagct tctactgctt gttcaacttt
     6901 tttagaaaca gccttaccag ctgcgcttgc tgactgttct gcacgcttca cgactttttt
     6961 tgtctcatct acaaccttag tcacagtact tgaaaaggca cctgcgcgac ggaggccatt
     7021 tcgtaattgt tttttacgat tgagtttctt tgacatgata aaatcctttc aataaaaaat
     7081 ccctgctctg acaaggattt aacataaaca ttctatcaag attttagtga aaaatcaaga
     7141 atctttctcg tttaataatt tcgctcacca aacaagcctt ctggcaaatc atggaatccc
     7201 ttgcctgctt tgaagttttc aaacttacca agcaagaact gataagcatc caagcgactc
     7261 tcgtagcgaa tcatggcatc tttggcacgc tcgtcctggt cttcttcgta aactttttga
     7321 ctttccttgt gcgccatatc gttaatcatg atttgggtat tgacccaagc ttcaaattcc
     7381 ttcataaatt cttgttcgta actcattttt tctccttatt ctaatccacg aaaatagtcc
     7441 gtatcaatct cacggtaggg ctggatatcc tgaacatact ccaacactcc ttggaattct
     7501 ccgtcttcat cgtgtactgc agcataggtg atgtggacaa acttacctcg cgactcagac
     7561 ttgaaccaca tttcatactt gtctttgctt ccctcacgaa gccccttcat gatagttttg
     7621 accttgtcca agtacttagg cggatggcag agttcgacat tgcgcccgac ttgggacggc
     7681 gtccgtttga aaatcatctc atcagctggc gtattgtcat tgtaatactg gaaaatatct
     7741 tctttattga caaaggtaat ctccataggg agatgattga ggatgagatt ggcctgctcg
     7801 actgaaagat agccattacc aaaagcctgt tgactatggc ggtccagcac agcttccttt
     7861 tccttagggg taaaggtaat ggtaaaatgg ccttctggcg tatctatgac ttgttgaact
     7921 tgaccttctg ccgtatctag ctgtacaggt tcctctgcaa tcttttcctc aataaagctc
     7981 tgtcgttctg gcacccattt ctctgacgga cggatgatgg catagccata ggcatcgctc
     8041 tcctccgcaa tctgaagcca gtcatcctga gtaaaagact caaggagaat catgaggagg
     8101 atggactctt ccttgaaaat catactttca aactctgtcg caaaagcttc aaaagcttcc
     8161 tttacactgc taattgacac ttctggtagt gacttggctg tcgttagagc tgtttgaaag
     8221 agttccctaa tctgatcatc cactccccac ataactttgg gaggtgaatc gtgtccatag
     8281 cgctccatga taggaaagaa gagttcttcc ttacgttggt aatggatgtc aaattgcccc
     8341 acaagcccca tctgacgcac caagcccttg cgcatctccg caagcatttc ctcgtcttcc
     8401 atagactcat aggtatctaa caatctacga atgcgaatca aggccgcacg gagagccaga
     8461 ttttcttctt tgaagacacg aactgggtga cctggatgct cagtatctga aacttcgaca
     8521 cctttgatag catttttaaa aagattggca tggacatcac agagttccat aacatcttca
     8581 aaggtgacac ctgagtctga gttcatcagc tcgtgctcca taagggaaat ctcaatggct
     8641 gagacacccg caaaggtcgc atcaaaacgc tcctgaaccg actcaggaga ggcgccatta
     8701 tgcaattcta ataaaatatc ccgtaggaca tgaatccgtt catctgtcat tagtctaatc
     8761 caatcacttc gtagccattc gcttccagtg tgcgtacaat cttgtccata ggagttcctg
     8821 ctagcttaga accctgttta agtgatactt tacgaccaac tgtattgcgc attaagggat
     8881 tggcaagggg tttaaaaccc agctccacta gaatttccaa gacttctgga tgcttgtcca
     8941 ccacttctgc aacaggaatt gacacatcga tgatattgtc catgacgacc tccattatat
     9001 gttctaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa
     9061 acaccgtttt gaggttgtgg atagaactga cgaagtcagt aacatatata ctgcaaggtg
     9121 aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgattttact gcttatatta
     9181 taccatatgg agagagatta aaaaactagc agtggagttc ctgctagctc tctgcgactt
     9241 ggattaccat ctagataagt ttaaagagcc aatccaatat cttaaataat atcttgtaaa
     9301 acagcaattg aactgcaaaa gaaatgatca tccaaaagaa tttcacaatc ccaataatcg
     9361 gtttgataaa aagaatagca agaagaccaa aaaaatttca ttctctctcc tctggcttaa
     9421 tgagccaccg agccgtatcc attagcttat ctgcaataaa aagtttgccc agaccaacaa
     9481 cgacatggtc agctttcttt atcgttttca tcacttttac accttgcacg gtcaaaaagt
     9541 aattaccata aattttagca aaagctttga taggattcat attactctcc tttgatgatt
     9601 tcagcctctt ttcggattgt ttcaacatct tcttgatatt gaacttcact atagttgact
     9661 agcttggata attctttctg caagctttcc cccattggtt tcatagttgc aaaggttaaa
     9721 ccacctgaaa tgataccacc caagatagga ataaatttcc ctattccttt ggccagccct
     9781 cccttggtaa gattcacacc aaatattctt aagacttttt tcaaaatagg gtaccaaagc
     9841 gtctttgtta aagctttatt aggcactgtt ttcattacct gtttggcaat tgttatacca
     9901 ccagcacgta gcaaacaaag cagcggttcc attcacccct aacattacgc ctagataaag
     9961 caagagggta ttttgagtat cttcactcaa ctcctcacgt gaagcccaaa gatcctcata
    10021 accataaata taacctaatt cttgggccaa tttcagagag aaaccataaa attgagccac
    10081 ataagctgga atggtaattg ccatagcaag ccctccaggt aatcctgcca aaacagaagt
    10141 cccactcgct aataaaacat tatccctaat acaggcatta gccactcgat ctaagatttc
    10201 ttgagataag agagacgttg gaccttgttc caataaggta ggaatgtcct gtggacccaa
    10261 ttctttggaa aacttatcca ctaaaaattt cgaacgatca accttaacaa ctggtagttt
    10321 taccacttgt tgtaatactt gcatagctaa gtcttgttca gccatataca aactccttat
    10381 ttcttttttg caccttatca tattatattt cctacaaaaa aagcattttc taattagata
    10441 acattaaaaa atacagaacc ccttttttat agtaaaataa aacaagaaca ggacaaatcg
    10501 atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggcgta ctattctagt
    10561 ttcaatatat tttaaaagaa tatttttcca tttcaaattc aacctatttt cctccaccaa
    10621 aaaagagggg caacccctct tctttagttc ttatccagat tgcgtagcat ctcgtcaatc
    10681 ttgtttccat actcgatgga ctcgtctttg acgaaggtca aatctgggat tttgtacaat
    10741 ttcaaattgc gaccaagttc acgtttgatg gtaccagttg ctttttcaag cccgatttgg
    10801 gctttttggt tatccgaagc aaggttactc aaaatggtgt aataaacctt ggcaacagac
    10861 aagtcaccca gcatctgaac atctgtgatg gtcacacctt ggacacgtgg atcacggact
    10921 ttcttttgca aaatctcatt gacttcacgc ttgatttcca tgcccacacg atctgtacgg
    10981 aaatgatttg ccatgatatt cctttctcta ctttgaacca aaagctaggc cagcagacct
    11041 agctatttta aacttcttga ttttcagttt aaattgaaac gaagttcaat ttgaagtcat
    11101 ctgcttcttt cgccgtggtg aaagtgatgg aactgattta tcagtcccat cacaggggat
    11161 ttttgagacc ctaggctcaa aaataagcaa tgaaaccatc ggtttgcttg cgtccctcac
    11221 cacctaagaa aggagcaaaa aatcttatct cttgatttct tccatgacat acgcctcaat
    11281 cacatcatcc atcttaatat cattgtagcc gtcgatcatc aatccacctt cacggccgtt
    11341 tgtaacttcc ttaacgtcgt ctttatagtg tttcaagctt gcgagttcac catcatagat
    11401 aacgacacca tcacggataa cacggacttt agagtcacgg gcaaccttac cgttgataac
    11461 cataaatcca ccgatagttc ccactttaga caccttgaag gtttcacgga taaccgcttc
    11521 accaataact ttttcttcaa attctggatc aagcatccct ttcatagctt cttccatctc
    11581 ttcgataacc ttgtagataa tgctgtgaag acggatttcc acatcgtcag cttctgcttg
    11641 ttgacgagct tgtggtgtag ggcgtacgtt gaaaccaacg ataaaggcat ttgaagcttc
    11701 ggcaagggtc acgtctgatt cgttgatagc accgaccgct gagtggacga tagtcacttt
    11761 gacaccttcc acgtcaatct tttgaagtga ggcagaaagt gcttcaacag aaccttgtac
    11821 atcggccttg atgataacat taacagattt gagttcccca gctttaaggg tatcaaagag
    11881 gttttcaagg ctaacacgtt gggtagcttg acgttgtttc atgagggcac gtttggcacg
    11941 ctcttcacct gctgcacgcg cagatttttc atcctcgtaa acggcaaagt ggtcacccgc
    12001 catcggtgct tcgttcaaac ctgtgataga gactggtgtt gatggtccag caactttaac
    12061 acgacgacca aggtcgttgg tcatagcacg gacacgaccg aaggtatttc cgacaacgat
    12121 tgggtcttga acattcaagg taccttgttg tacaagaagg gttgcgaccg caccttttcc
    12181 tttatccaag cgcgcttcga taaccgtacc gattgcacgc actgttgggt ctgccttgag
    12241 ttcttggatt tcagctacaa gaaggactgt ttccaacaat tcttcgatat tttggttgaa
    12301 tttagctgag atttcaacaa attcagaatc tccaccccaa gcagttgaca taactccatg
    12361 ctctgccaat tcaccgataa cgcgttctgg gttagcacct ggtttatcaa tcttgttaat
    12421 ggctacgatg attggaacgt tggccgcttt tgagtggtta atggcttcga tagtctgagg
    12481 cataaccccg tcatctgccg ctacgaccaa gatcgtaata tcggtaacag aagcaccacg
    12541 cgcacgcatt gatgtaaagg ccgcgtgtcc tggtgtatca aggaaggtaa tcttcttacc
    12601 attttccacg atttggtagg caccgatatg ctgagtaata ccacctgctt cacctgtcgc
    12661 aacacgtgag ttacgaagag tatccaaaag ggttgtttta ccgtggtcaa cgtgtcccat
    12721 gatagtaaca actggtggac gctcaaccaa ttcatcttca ttgagataac catcttcgac
    12781 aaagaaacgt tcgatgtcag cattatccac ttcaaccttt tgtttagctt cgataccgta
    12841 atccaccatg aggagttcaa ttgtttcccc atccaaggat tggttttgtg tggccatgac
    12901 acccatcatg aaaagtttct taacgatttc agctggttca cgtttgatac gttttgcgat
    12961 ttccgcaacg gtcataccat ctgtatattc aaattctgtt ggcaattcat ggaatttacg
    13021 ctccgtaaca ggttttggag tctgattacg gttgttcttg ttattgcctt ttttgttctt
    13081 tttgttgtta ttccagttac tattcttttg atttctcact tgattttgac tacttcgatt
    13141 cttttgttgt tttctaggac catcttcttc atgatcataa tcgtcacgat ttttgtctgg
    13201 tcgagcttgt tttttacgac gtgtatccac tgcaggttct tttttctcag ggacgacttc
    13261 aaccactgct tgaacttgct gtgcttgttc agctaactta gccgcttctt caaagatttc
    13321 ctctggttcc ttgcgtttgt tagcttgagc caaggcttct ttagcagcct gatactgctt
    13381 gaagcgttcc tcacttgaac gagcgtactc tgcattttgc tctgctttta gggctgctgc
    13441 acgggcttta aagtcaatac gtggagccac ttgatttgaa cgtttgtcct cttgctgacg
    13501 gcgctcattt ctacgttttt gctgaccttg ctgcttctta gcttggtcat taaagcgacg
    13561 attgtcgcgg ttgctttgac cttgttttcc accattacgg ccgtcgtttt tctgacggtt
    13621 tccgttttgt tgttggtcac ggttattgcc cttattttgc ttgcgtcgtt ctgcctgctc
    13681 tttagcacgg gcttcacgct cagccttgaa attacgactt tgcggtttcg ctgctacttt
    13741 ttctgttttc ggagcaactg gctcagccgg ttttgcctct tccttagcta cagctggttt
    13801 agctggctca gatttttcgg ctttcttttc tgcacttact tttggtgctg caggttttgc
    13861 ttctactttc ggagcagctg cagacttaaa gctggcagca atttttgcag cgacagcttc
    13921 ttccacactt gatgagtggc ttttcacatc caagcccaac tcttttgcac gcgctacaac
    13981 ttctttactt tcttttccaa gttcttttgc gatttcgtac aatcttttct tagacaaatc
    14041 atgtcctcct cttctattcc ataagagacc tcattttctt tgtaaatcca gcatctgtta
    14101 cagccaaaac ctttctcgat ttcccgactg ctatgcttaa ttccagtgtt gaaaacacgg
    14161 ttacaatttc tacttgataa taatgacttt tatcttgaat cttcttggtc agattgggtc
    14221 cagcatcatg agctagaaag accaacttgg ccttgccgtc ttgaatggcc ttgaccacca
    14281 attcttcacc cgatatgatg cgccctgctc gctgagcaag ccccaagaga ttacttatct
    14341 tttgcttatt caagtcccaa ctctcttctt ttcactttgt gatccacata agcgatcaac
    14401 tcgtcataaa agctttcttc cacttccatg ctaaagctgc ggttaaagac cttcttcttt
    14461 ttcgcctcta gggcttctgc attgtctagt ttgatataag cgccgcggcc attggccttg
    14521 cccgtaggat caataaagac ttgtccttcc ttgttcttga caatgcggag caaatcacgc
    14581 ttatcaatca cttcgttaga cacaacagac ttgcgcaaag ggatttttct tgttttcatc
    14641 tttccctcct ctagcagctt ttattcttct acagtatcgt tttctacttc caactctact
    14701 gaagcagcgt cttccatggc ttcaaattcg ctagcagact tgatatcgat acggtaacca
    14761 gtcaagtgag ccgccaagcg cacgttttgt ccacgacgac caatggcaag agaaagcttg
    14821 ttatctggaa caaccaccaa ggcacgtttg ctgtcgtttt catcaaagat aacttggtca
    14881 acctcagcag gagcgatggc attgtagata aattcagctg gatctgctac ccactcgata
    14941 acatcgatat tttcttcgat tggtaccatg cggtcatttt tagcatcgta acgagctggg
    15001 tggaatttgc tagtaatctt cttgatatta gcaccaccac gtccaacgat tgtaccgata
    15061 gcatccacgt ttggattgtg gctacgaaca gcaaccttcg tacggtcacc tgcttcacga
    15121 gccacgctca tgatttcaac agttccatca taaacttctg gaatttcttg ctccatcaaa
    15181 cgtttgatca tttctggatg gctacggcta acaaagacgt tcacaccacg agggttgtct
    15241 tcaaccttgt aaacataaac ttcgatacga tcatgagaag caaaaacttc tccaggaatt
    15301 tggtcttgtt ttgacaattg ggcttcgatg ctaccaaggt tgacatagat aaagcggttg
    15361 tcaaagcgtt ctactgtacc agacatgatt tcttgctcat gttctttgta agtattgtaa
    15421 gtgatggcac gtgtttgctt gcgcattttt tccatgatgg tttgtttggc agattgggct
    15481 gctacacgac caaactcagc tggtgcttct tcaaacttga ttttgtctcc aagttcataa
    15541 gctgaattaa tggcaagagc atctttcaag ctgatttcca aacggctatc aaatacttca
    15601 tcaacaactt cacggacagt ataaactgta aagtcacctg ttttttcgtt gaagtcaata
    15661 gctacgctgt ctgactgacc atagcgtctg cgataagcgg aacgaagcga ctctactact
    15721 gcgtcgatga tatcttcttt tttgattccc ttgtcttctt ccaaaatgcg gaaggcctct
    15781 agcatttctt tactcatgtt ttcttcactt ttgaatcctc aaaagctatc ctttcttttt
    15841 ctataattta actgctaaac gtgcttttga tactaaactg tatggaattt ggacggtttt
    15901 cttacgcgtc ttgtccatat attccatagt caactcgtcc tcttcgaagg ccaacaaggt
    15961 tccttcaaag accttttgct tatcgatggc ttggtagagc ccgacatgga tgtattttcc
    16021 aaccgctcca gcgacggcat ccttggtttt caaaggacgt tccaaacctg gactggtaat
    16081 ttctaggaaa tattgttctg ggaagggatc tggcttgatg gtgtctagga caggactgat
    16141 catttctgtc aagtctgccg tgtcgttcaa ggtaattcct tcgggtttat ctacaaaaat
    16201 actgagaatc atgtcactgc caatctttcc atactcgata tccacgagtt caaaaggagc
    16261 ttctatgaca ggttctacaa cttctctgac taattctacg attgttgcga ttgcgtccac
    16321 ctcctcataa gcaagaggcg aagatatttc cccgcctcac ttttcatatt cttactatca
    16381 gtatagcacg tttgccaact tatgtaaagc aaaagcactt gtacagccta attttaggct
    16441 atctcttaaa attctgcctc aactcggtag ataacttgcc ccttgtttga gaatttttgc
    16501 tcgtattctg tcatgacatt gccttcaaaa tcactggcat gcaaatctaa ccagacacca
    16561 ttgagtttca tgccatattg agaaaagctc actaaactgt actcaaacaa gccacggtta
    16621 tccgtcttga aatgaatttc tccattttca ggcaagatac gtttgaaggt atccaagaag
    16681 gtcttgtagg tcaaacgacg cttttcatgg cgttttttcg gccatggatc tgaaaagttc
    16741 agatacaagc gatcaatctc accgtcttca aagtagtcag ttaagtcaga accatctacc
    16801 cacaagagct tgatgttagg cactccaact tcaagcacct tgtccaaagc gtagctcaaa
    16861 acagactttt gaatatcaat cccgatatag ttgatgtcag ggttttgctt ggccatacct
    16921 gaaacaaagg caccctttcc acttccaact tccacatgaa tgggattatc attgccaaac
    16981 aagtcccgcc attttgcctt ggcttccaag ggattgagga ccacatactg gggatttgcc
    17041 tctagtaatt ctgttgcccc tttacgattt ctaactctca tcttctcttt ccatacttgt
    17101 ctcggaaatg acgcaaacca tgaatctccc gattgacatt ttctaaatct tggttcatat
    17161 aatacttgga aatctgactc aaataagaca attgaccata ccaatacaat ttacttaata
    17221 ccgtttgatt gtacttgtaa ccgtagtagg tcaaccattc cttccactga tgttctgaaa
    17281 tataatggca gagcatatgg gccacatcaa acatgcgatc ggtcaagcga accgaatccc
    17341 aatctactaa ataaatcaag ccactatctg tctcaatcca attactatgt cgtacatctc
    17401 catggacaat ggtcgcatgg tcctctctaa atcctggaat agtctgacgt aaatcagcca
    17461 tcacttcact gataaaatga tttttacgca aagcatctgg agccgtttcc tgccaagact
    17521 gtagtaaatc tacaggtgtt tccatggcat agcccaaacg actcaattgt gtcatcaacg
    17581 gacgtgagcg atgaagacgg gttaaaatat tgacgatttg cttacgattc atatcatagg
    17641 gggtcaatat cttgcctgtc aaccattctt gagcacacat atcacgccca tctgccaaac
    17701 gacgactcca taataattgt ggagcaattt gttctctagc tagaccaggt aggattggag
    17761 aggtgttcat ttttacaaag atgcgcttcc catcaggata gctacccata taagccttgc
    17821 cacttttccc aggtatggga gtcagtgtta gctcattatc acccaaatcc atttctttcc
    17881 tccgtataaa gtttccttac tattctacta gtttttggcc tattcgtcaa ccactctaac
    17941 ccgattctca aagaaaagcc tctggagtgg tttgggttat cattatagaa agaaaaaggt
    18001 aagcacaatc tcctacttac cttttcatga tttttataaa taatataaga gtggccaact
    18061 gttgtaaagc atatggacta gagtagaaac ccataggttt tggctctttt tataagcaaa
    18121 gcccagcaac aaacccccaa gtagataaaa aataaacgaa gggacattag aaggtccatg
    18181 catgaaagaa aagagagagg aagttagcac aagccctaac caagaattgt caaaaaccgc
    18241 accttgaaga agtcctctga aaatgagttc ctcctggatg gggccaaaaa ctgaggtagt
    18301 caaaatcaaa gacagggaaa ttcctctgct gacttccgcc aagtgttgga cccctgagcc
    18361 agaagaaaca gcgaagaaat gaatataaac cagcgtctca agtacactta gaagaaagat
    18421 tgcaatgaaa agcaaaagtt gtttcttgct taacatccca aaagaaatca tttcaaactt
    18481 tctagcataa gcaacactca gcgaggttac aagaagactt acaataatca atgcagattc
    18541 attttgaaaa aaatccccat ggttaatcgt ataaggaact gtaatgacaa ttattagtac
    18601 taaaaatcca aaacacaagg catgaaattt atcaaaaaac tccataaaat tatcctcctc
    18661 aacaaacaga cttcctacac gtcattcttt agatctagcc tttccaaaac aaaccatttt
    18721 agcaaccaaa atccgaccac atagccagcc cctatgaata tagccattaa agctagcatg
    18781 gaatttagga aattaaaaac caccgcagat acaaaggtta gcacaaaaac attaaaagca
    18841 atggtgtcag aagccaagac tataatatag ggtgtcaacc gatctaaagt tttggaatct
    18901 aggaaaaata agtgtttata catgatgacc tcctctatgg ctgaaaagca agccttttgt
    18961 tttttttacc ccaagaccct atgtagaaaa gtgagcaaaa acgggaaggt cgctacaata
    19021 ttattgatca catgcaccgc ataggatgga taaatactct tggtatagcg ggtcaaaccg
    19081 gcaaagatga ttccaaatgt tgcaaagacg aagatatcta acagactagg cagactcaaa
    19141 aaatgaggaa gagcaaacaa aatggaagga agaagcaaat caaggccaaa tcgcgaatgc
    19201 ttaaagaagg cgtgttgcag taatccccta taaatcaact cttccattag tggagtcagg
    19261 aaaaacaggg ttacatagat acctagctca gcaaagttgg tcccactata accgatcaat
    19321 acggcccaac cttcagcggt tgactgaaca tgtttagctg tctgaacgtt aaaagagata
    19381 tggagcacta ccactaatac tgtcaaaata gaataccaaa gccatttttt tcttggaatg
    19441 cgaaagagat agccatggcc tgtcttaacc agaatccaaa tcatgactcc gctaaatagc
    19501 agactcaaga tatttctaat ccagaaaaaa tttcctacct gagaagaaaa ttgccaatga
    19561 ttttggacga taagagttaa ctgagaaaga ccaaatacga aaaataggta agacaagact
    19621 gcacttattt tgaaaacaag ctgatacttt ttcatagaaa ttcttcctca tttcttgtat
    19681 ttcagcctat attccacata aatgaaaacc tgctcctata taaccacggt catgataacc
    19741 gcgcgggcag taaccactta ctggaaaagg acctgaattt tttaatatag gagggtaaga
    19801 accgaatgga cttacctgat tagcgtaccc tctataaata tcagagacat ccccaccctc
    19861 tatacgagca agcatttcat tatccataac tgcaaattgt gacatcattt ttgtatccat
    19921 gacgaatatc tcctttttta tgtttaattt ttgtcctgtt gcaaccttga caagtttagt
    19981 atatcatcgt ttattaattt ttttcatcca aatcttgaat tgtcatcgaa acgtcttgaa
    20041 ttgttaaaaa atttaaaaag caagcattaa caacatactt gccctttcac tcttgtctat
    20101 aggcaaattc tagctatatg ttattacaaa caaatagtat catttcacct gtttaccatc
    20161 tatttttatt tatgaatttt ttgtttcact ttaatcatta tagaagccat aaaaaacgcg
    20221 acagctagtc gaatcagttg gtaactttct tcctcgcctg ttttcagtaa taatttttca
    20281 ttcgaagtaa tagattcgct tacataatca gcatccttaa catcagttaa agaagtttta
    20341 ttttcttgag cagcatcaaa aataggtttg agagtttcca attgattctt attgtctaac
    20401 attgctaaat tgccagattg agtagtttta gcttcagaag ttgagtttgt actctccact
    20461 ttcccactat tttcactatt agcattggat attttcattt cagttctttt tttatcactc
    20521 atacctttgc tgtcacttac aactttatca ctaatattca tgctgtcact tctagtattc
    20581 tcatcacgga cactttcagt tactgtttcc tcagaagatt tcactgtctc cgtttgctta
    20641 ggtgagtttc tcgaatacat ataatcatac acctgttgtg cagttgctcc gccaccaacc
    20701 catccagatg tcggatgtcc atttcttaaa tacaaaattg ttggtgttcc tggaataccg
    20761 acttttttaa aatagaaact ctctcgcttc cccatcaaaa tccttaccat ccaaatcata
    20821 atactctaac ttcttttcaa tcaagttatt aaattctttc aattcaggag aaaattgacg
    20881 acaatgagag caagtttttc taccaaaata aatagtatgt tccaattgat cccctgtaaa
    20941 agattgacga acagcttcaa tatctatctt tttaaagtcc gtaacattct tctcatactc
    21001 ttctggggtt acaacagaag gcttatgctc caccttttcc ttagccgatg gcaaatctgg
    21061 cgccacaaga gaactatcat tcgcctgggt agatgaagta gtaggctgtt cttctgcata
    21121 tgcaagacct gcagtaatag atgcaaatac aagtggtaca agtaatagcg attttatctt
    21181 ttgtttcttc ataagaatac tcctttacat ttgttatctt tatcttacct tatttaagat
    21241 tacaaattca tctaaatctt aaatggtcat cgaaacatct tgaattgcaa aaacttcatt
    21301 ataaaagggt aagtatttca aaaacactta cccctttata ctttattaag ctctactttt
    21361 tataatactt caatccccaa atgagcagaa gcatgatggt caagcagaga atagcgccaa
    21421 tgtaggcaat tatttgttgg taggattctc ctgctgtgat ccctctatac aaacaaataa
    21481 tagacataaa acctgtcaag ccgatgaaca tgagttgatt agttctagga ctaaccaaat
    21541 catcgtcttc aaactctttt atccgcattt ccctagtgag gtaaacagtg accaaaatag
    21601 aagctaagtt aataaccact aaaaaaaatt ggaaaactaa ggaaaaattt aaaaactgac
    21661 gagatagaaa tagataagta gagacaagca agggcaactg acctaagaac aatctcgcaa
    21721 ggaagatgtt ccgtttttta gcaagaaaaa ttttcatttc ttttctcctt tctttttatt
    21781 gatagcaaaa tagatcataa ctgcaatcac ataggctatg gtataaaata gctgatacca
    21841 agcactctcc ctaagcggat atagaaagat ggacatgatt agatacagaa cgaaaataat
    21901 cagtattttt ttcttcataa gatttcctcc taaatgtgtg ctttatctta gttgagcaag
    21961 aacatttaca ctgctagtat agcacttatt ttgaccttgg atcactcaaa tcataaatgg
    22021 tcatcaaaac ctcttgaatt gtaaaaatta aaaaaagcaa gcatgaaaaa catactttcc
    22081 tctttatatt gtattgatac caacttgttt gtagactttt catcctgcta tcacatatca
    22141 ttttgacagg cgaaacaaaa ttaaagaaac tcccctgtaa attaagctag caaatacagg
    22201 ggagaaattt attttttagg gggtactatc tgtatccttt ttgggagatt ttgaaaatat
    22261 ttttctaatt aaatcatcca tataaggacc aaatatacca actactaaac caataataaa
    22321 acttttaaaa tccataatta ccaccaacat gttgctgcat aggctacacc tccaagtata
    22381 gctccacctg cagcaccagt tacacctatt cctatagcaa atggtcccaa tagaaatgtc
    22441 aaaccgttgt tacacaccca tcaattgcgc catatgcaac ccctgctgca caactaattt
    22501 ttcttcccca atcaatatct ccaccttcaa cgcaagcaag catttcatta tccataacag
    22561 aaaattgtga catcattttt gtattcatat agtatgtcac ttttcagtta cggaacaagt
    22621 ttaatataaa aattatcaaa aaaacatagg caataaagag aaaaattaat ttatcataga
    22681 ttagaaataa tatgacaaaa caattcaatg atgttaattc aatagtcttt tgttttttat
    22741 cagagatact tatggataga taaataagat aggtttgaaa agcgaagaga ataataaaga
    22801 atatagcctt cataaaattt agctttcatt tttatgatgt agcggtatag gctaaatatc
    22861 cacaaaccac tgctcctcct attgcagcgc cccatggtcc tagaattttc ccatatttca
    22921 ctccacccgc tgcacaacct aaagcagcaa ctacagctgc tcctccggaa ttacctccgt
    22981 aaacctcact cagcattgtt tcatttatat tacaataagt attcatacaa gtctcctttt
    23041 gttaaaatcc acccgttgcc cctgttactc ctgcccaaag agccacacca aatttagctc
    23101 ctatgtatcc acatgctccc ataaatggtg ctccaacacc actcgcagca caaatagctg
    23161 tccctaaccc ccagccacca aaagcggcac caccaccttc taagacatta gtttgccaat
    23221 tattcttgcc tccttcaata ctagataaca tagttatatc cataatctca aattgttcca
    23281 tcatttttgt attcatgaca aatactcctt ttttattttt tatttttgtc ttgttgtaac
    23341 cttgacaagt ttagtatatc attatttttt aatttttttc atccaaatct tgaactgtca
    23401 tcgaaacgtc ttgaattagc ttttttattt caagccacct ctaaatgttt aaaaaaaata
    23461 atttctaatc acttttttac cattcaggaa gttttaatga ctattcaaga tttcataaaa
    23521 tatgaactta tttttatggc ataatatacc tatccactat attaaaggaa ttgccaatga
    23581 cttcttataa acgtacattt gttcctcaaa tagatgcgag agactgtggt gtcgctgcct
    23641 tagcctcgat tgctaaattc tatggttcag atttttctct agctcacttg agagaacttg
    23701 caaagaccaa taaagaaggg acgactgctc ttggcattgt aaaagccgct gatgaaatgg
    23761 gctttgaaac aaggcctgtt caagcagata aaactctctt tgacatgagt gatgtcccct
    23821 atccatttat cgttcacgtt aacaaagaag gaaaactcca acattactat gttgtctatc
    23881 aaacaaagaa agactatctg attattggtg atcctgaccc ttctgtaaaa atcaccaaaa
    23941 tgtcaaaaga acgctttttc tctgaatgga ctggagtagc tatttttcta gctcccaaac
    24001 ccagctatca accccataaa gataaaaaga atggtctact aagcttcctt cctctgattt
    24061 tcaaacaaaa atctctcatt gcttacattg ttctctcaag cttattggtc actattatca
    24121 atatcggtgg ttcttattat ctccaaggaa tcttggatga atacatccta aatcagatga
    24181 aatcaacttt aggaatcatc tcagttggtc tggttattac ctatatcctc caacaagtca
    24241 tgagcttctc cagagattat ctcctaactg ttctgagtca gagattaagt attgatgtga
    24301 ttttatccta tattcgccat atttttgaac ttcctatgtc tttctttgcg acacgtcgta
    24361 caggagaaat catttcacgg ttcacagatg ctaactctat tatagatgcc ttggcttcta
    24421 ccattctttc tctttttctg gatgtttcta ttctgattct tgtaggggga gtcttactgg
    24481 cacaaaatcc taatctcttc cttctttctc ttatttccat ccctatatac atgttcatca
    24541 tcttttcttt tatgaagcct ttcgaaaaaa tgaaccatga tgtcatgcaa agtaattcta
    24601 tggttagctc tgccattatc gaagatatca acgggattga aactataaag tcgctcacga
    24661 gtgaagaaaa tcgctatcaa aatatagaca gcgaatttgt agattatttg gaaaaatcct
    24721 ttaagctcag taaatattct attttacaaa cgagtttaaa gcagggaaca aaattagttc
    24781 tgaatatcct tatcctatgg tttggcgctc aattagtcat gtcgagtaaa atttctatcg
    24841 gtcagctaat tacctttaac acactttttt cttactttac aactcctatg gaaaatatta
    24901 tcaacctcca aaccaaactc caatctgcga aggtcgctaa taaccgtttg aacgaagtct
    24961 atctagtcga atctgaattt caagttcaag aaaaccctgt tcattcacat tttttgatgg
    25021 gcgatattga atttgatgac ctttcttata agtatggttt tggacgagat accttaacag
    25081 atattaatct cacgattaaa caaggagata aggttagcct agttggagtt agtggttctg
    25141 gtaaaacaac tttagccaaa atgattgtca atttctttga accctacaaa gggcatattt
    25201 ccatcaatca tcaggatatt aaaaacatcg ataaaaaagt cttgcgccgt catattaatt
    25261 acctaccaca acaagcctat atctttaatg gctctatttt ggaaaactta accttgggcg
    25321 gtaatcatat gattagccaa gaagatattc taaaagcttg tgaattagct gaaattcgtc
    25381 aagacattga aagaatgcct atggactatc aaactcagct ctctgatgga gctggtctat
    25441 caggaggaca aaagcaacga atcgctctcg ctcgtgctct tttaactaaa gctcctgttt
    25501 taatactaga tgaagctact agcggtcttg atgtctttac tgagaaaaag gttatagata
    25561 atcttatatc cctaactgat aaaaccattc tctttgtagc ccatcgtctc agtatagccg
    25621 aacgaactaa ccgtgtcatt gttcttgacc aggggaaaat cattgaagtt ggtagtcacc
    25681 aagagttaat gcaggcgcaa ggcttctacc atcatctatt caataaataa ggagaatgtt
    25741 atgaatccta atctttttag aagcgtcgag ttttatcaga gacgttacca taactatgcg
    25801 acagtgttaa ttatacctct ttcattactg tttactttca tcttgatttt ctcctttgtt
    25861 gccacaaaag aaattactgt tacttcccaa ggagaaatcg cccctacaag tgccattgca
    25921 tctattcagt cgaccagtga taatcctatc cttgctaatc atttagtggc aaatcaagta
    25981 gttgagaaag gtgacttact catcaaatac tctgaaacaa tggaagaaag tcagaaaact
    26041 gccttagcaa ctcaattaca aagacttgag aagcaaaaag aaggacttgg aattttgaaa
    26101 caaagcttag aaaaagcgac tgatcttttt tctggcgagg atgaatttgg ctaccataat
    26161 acctttagga attttactaa acaatcccat gatattgagc taggtatctc aaagactaac
    26221 accgaggttt caaatcaagc taatcttgcc aatagcagtt catcagccat cgaacaagaa
    26281 attacaaaag ttcaacaaca aattggagaa taccaggagc tgagagatgc tatcataaat
    26341 aaaagggctc gcttaccaac tggcaatccg caccagtcaa ttttaaatcg ttatcttgta
    26401 gccgctcaag gacaaacaca aggaactgca gaggagccat ttttatctca aattaatcaa
    26461 agtattgcag gtctggaatc atctatcgca agcctcaaaa ttcagcaagc tggtatcgga
    26521 agtgtagcaa cttatgataa tagtttagca accaaaattg aagtactccg cactcaattt
    26581 ttacagacag cctcacagca acaactaacc gtggagaatc aattaacaga attaaaagta
    26641 caactagatc aagcgacaca gcgcttagaa aacaatacct taacagcacc aagtaaaggt
    26701 atcattcacc taagcagtga atttgaaggt aaaaatagaa ttccaactgg tacagaaatt
    26761 gctcaaatat tccctatcat cacagataca agagaagtac taatcactta ctacgtagct
    26821 tctgactatc tacctctact agataaagga caaactgtaa gattaaaact ggagaagatt
    26881 ggaaatcact gcattaccat catcgcccaa cttcagacaa ttgatcaaac tcctaccaga
    26941 acagagcaag gcaatctctt taaattaacc gctcttgcaa aactatctaa tgaggatagt
    27001 aaactcatcc aatatggctt acaaggtcgc gtcactagtg taaccgcaaa gaaaacatat
    27061 tttgattatt tcaaagataa aattctaacc cattctgatt aattttcaga taacactcta
    27121 taactattta ttatcttatc aaaaaggaga attgtaacat ggataagaat caaaacctaa
    27181 cttcattcca agaactaaca actactgaac tcaaccaaat tacaggcgga ggatggtgga
    27241 aagatttatt acatagattt aatgtaattg aacaaaacaa tacaaaagga tttaatcaac
    27301 caatacaact ataaaaaata agaccgagaa acaagaattc tcggtcttat tttcatcatt
    27361 ctgtatgtat catagtaagc acctgacgaa agacttgatc ttgacaggta gtatttaaac
    27421 tggcattggg ataactttcc acaatcttca taacggtata gagaccgaca cctctctcct
    27481 cccctttaga actaactcca aaggagaaga tttcagaaat atcgatgccc tcttctttga
    27541 tagaattttc aatgataaag gtctcctgtg ctccattttt taaaaaggca attgaaacat
    27601 gaggttgact agcctctgca ctcgcttcaa tagcattgtc acaaaggata gacacgatgg
    27661 ttagaaaatc aagcaggctc atcccctcga cctgaatctc ctcaggaact tcgacattaa
    27721 agataatctt cttatctcta gcttttagaa atttccctgc tagaagactt ttgagggcac
    27781 ggtcacgaat attcaccaat ctgcccaggt catatttatt gtcctgcaat ttctgactgg
    27841 aatcctttaa aacagagtcg taaacctctt ttatctgctc catatcctcc tcttcaatac
    27901 ccagacgtaa actggtcaag aggttggtgt agtcatggcg aaaactcctt acttccttgt
    27961 aaagttcctc tatatgccga ctatggcgtt ccatatctct atagcgcaag gtctgctctt
    28021 ggttcagtct ctcatggagt ttgttcttca aataggtatc caatttcttg ataaccccca
    28081 taaaaaatag gaggtagaac actaggatga gatggcgaac agtcgttgat tgaatacctt
    28141 gctcatattc aaagtaagac agactttgta tcaccaaata gtaagccccc attatccagt
    28201 taatcttagt cagggacttt tgaaaacctg tatctagaat ctcccttctc aaactagtaa
    28261 aatcatagtc caaccatttc aaaaaggcta gagaaatgaa gaaattgaaa attattatac
    28321 ataacccagt gaatgagtag ccatcatata cttgcccttg tcccaaaaat ggaagcacaa
    28381 aataggagac tcctctataa aagagattca ccaatatcat tggaaagaga ccataaaaga
    28441 aaaggagttt tttaggaagc cctcttaaca ataagaaaga caagcctatg ccgtacaagg
    28501 gttccataaa ataagatagg taaacatttc ctactatata gctaatcatt acaaaaacaa
    28561 agaccaacag tatcttcaaa agaaaggcct taaaaatcct ctcgaaagta agattaattc
    28621 catccacctt aaagaaaatg acaatttcta gcccattagt aataagtgta tgcaataata
    28681 tccaaacaat attcataaac tctcctagtt cagtgtaagt tattaatagc ctcagacact
    28741 tccctgacct tataacgcac gatcagacaa cttccaccat tgggaaggaa aaggagtttt
    28801 tctttcttat ccaaatgcac cacatttgca ggattgatga gaaaagagcg atggcactgc
    28861 aagagacggg gttcctgctt gaaaacctcc tctaaactcg ctgtaaattc cagcctgtct
    28921 gtcttggtat agagaataac acgatgggct ctgggagaca tttcgagata gtaaacctct
    28981 ttaaaaggat attggaattg ggcaaatttt gatttaaagt aaaagcaatc ttccgccaga
    29041 cttttactat cttgactatt ggcatagagg agggctgtct cgatacgaga ttcaaactcc
    29101 tctgccgaaa gggccttatc aatgtagtcc aaagctgaca cttggtagcg aaaggacaga
    29161 ggcataaact ccgagtgagt cgtcacaaag acgattaggg cataagggtc ccgatcccga
    29221 atctttctag ccacttccag ccccttcatc tcctcatttc gaatctcaat gtccaaaaag
    29281 aatagctgat gggcccccct tctcatgcac ctctgtcagc agttggtccg gcttgccaaa
    29341 tacctcaaaa gagctaggaa tgatatgatg tgctttcaaa agtttctcaa tcgtcgtttc
    29401 aattctagtc tgttgggaaa aatcatcttc taaaacaaat attctcatct tcttactctc
    29461 cctctttcaa ccatttttga cgaatttctc tatagcgacg tctggcatac ttgacagcgt
    29521 attgaccttc ttctccgaga aaaaggattc ttttttgaaa atcaatcgat tttaatttat
    29581 caagattaac caaacaattt cgatgacatc tcatcaaggt ttccccatat tggttctcaa
    29641 gattacttaa attttgaagc atattaaaac tagcttcttc tgtaacaatc tgtacggtat
    29701 gggctttagt tggatgtgtt tggatatagt agatatcgtc gacgtttact ttatagactg
    29761 ttttctgcgt ctgaataatc atatgtttca ttggattctc ctcctaagaa aagaataaca
    29821 gaaaagttct agcccaagcc cacccaatcc taaacagtct ttgaaagctc ctaaaaggat
    29881 tatttttcta caacatcatg atgagcttac aactatttta tcataaaatt cactcagcgc
    29941 aattaaagat ttgaataaaa aaaaagaatt aaaaatgata aactaacagt atcaaaacac
    30001 agttgccaga agtaagactg gcacccagat taaaggagga attcccatga cagatacaga
    30061 ccctatcaaa agagctcagg ctttgattac tgacttaaac aaagcctatc aagcatgcaa
    30121 acaggcaagc gctgacgacg tccgctttca ggagcaatta aactctattc ttggttttct
    30181 agccaaggct gagacagcgg ataatcgagt cttgattgaa ctggaaaaat tttaccagac
    30241 ttccagtctt ctcatgggac tcagcgctct tgatccagat gctccaactc gcgccgcttg
    30301 gcgggcctat gaccgcttcc actttgacca agtcaagacc aagttgagcc tctacggtcc
    30361 aaccattatc ttgtaaaaaa taaaagaagc tgagacagat tgaactcaac ttcttttttg
    30421 ttccatataa gcaatgttag tcctgcatct gacgttttac ctgataaggc aaatacaaga
    30481 cttgtaaaac caaacctgca cccagcaagg ctagaagggc tagtttttct tggaaggtca
    30541 caaggccgac aactaattcc accactaaga ccaaactagt caatcctcgg actaccgcct
    30601 gcaagccttt ttccttttgc cccttgtcca gcggaaaaag ttgggtcaaa tactggtagt
    30661 caaaggcgtg atagagggcc agcaactgaa agagcaagag gtagttaaac agaaccacta
    30721 ccgctgtcgc aatccaagat tgctcaataa agacctgcgc cagcaaagaa agcaagagca
    30781 gacggagact aagggcaaaa aggtctccat ttcgcaaata agaacgcaga tagagatttt
    30841 gccaaatctt cccaggcacc ttctgaacaa cctttagaat aaagtccaga taggcacgac
    30901 gcttgacgct gtttgaaatt cccttgacct gcgtaaagag ggcaaagaaa cgaagcaaga
    30961 cttgcttacg cttgctttct tgggaaatga catagtccca atccagtcca gtttcagtga
    31021 aaaatttgct ggccttttga cgaaagagga aatattttcc tacccccaat aaaagcacat
    31081 aaaccagaaa aacaggcaag ccataaccca tggctaaaaa caagggcgca aataaaagca
    31141 agaagagggt ctggacaaaa atccaaaaga ctagggaaat gccggtttga cgcttgagat
    31201 ggagcttgat ttcctcttct ccaactaaga gaaagagctt gtctggagcc tccatatagg
    31261 tggcaattcc tccccaaagt aaaagtaaaa cagacgtaat tcctacaaac aaaaggatag
    31321 gccaatgatt ttcaggaaaa tgttgtaaga gttgactgta ctggtaggct agaaagccca
    31381 acagtacaag caggaacaag acaaagtggt cattgagaac atagcgcaga taaccaagac
    31441 actccttacg aaaggcctgc tttctcttta aaaacaagtc tttcataggt cctcctcttt
    31501 tgtcagagcc aagtaaatat cattcaaact agcctcaggc atatcaaagg cttcgcgtag
    31561 ttgcaggaga ttgcctttgg cacgcacctc tcccttgtga agaatgacaa aggcatcaca
    31621 catcttctcc gccgaatcca gcacgtgggt actcatgaga atagactttc ccttttgctt
    31681 ctccacttcc aaaagctgaa tcaaatcaga aatagccagc ggatcaagac caaggaaagg
    31741 ctcatccacg atgaaaagac ttggatccac cacaaaagca cagataatca tgaccttctg
    31801 cttcatccct tttgaaaaat gaacagggaa ccagtctaat ttctgttcca aacggaacat
    31861 ttttaacaag ggctctactc gttcgaaagc cactttttgc tcaataccgt aagccatagc
    31921 aaccgtttcg atatgctctc tgagggtcaa ttccttatac agactaggcg tctcaggaat
    31981 gtagccaatc tgcttgcggt agctagtcgc atctccttgc agagtcaggc cattgatatt
    32041 gatggagcca ctataaggtg ccaacagacc gataatctca ttgatcgtcg ttgatttccc
    32101 agcaccattg agaccaatca aaccgaccaa ctgcccactt tcaacagtaa aggacacatc
    32161 tttcaaaaca ggaacatgaa catagccacc tgtcaggttt ttaatttcta acatattttc
    32221 tccaaatctg gtataatgta gctatattat atcaaaattc agtacagtag aggtagattt
    32281 tatgtcagat tgcatttttt gtaaaatcat cgcaggggaa atccctgctt caaaagtata
    32341 tgaagatgag caggtccttg cctttcttga tatctctcaa gtaacactag gacacacctt
    32401 ggtcgtgcca aaagaacact atcgcaatct tttggagatg gatgctacga gcgccagcca
    32461 actctttgcc caagtaccaa aagtagctca aaaagtcatg aaagtcacta aggctgctgg
    32521 tatgaatatc atttccaact gtgaagaagt cgctggtcaa acagtttttc atactcacgt
    32581 tcaccttgtg cctcgctaca gtgctgacga tgacctcaag attgatttta tcgcccacga
    32641 accagacttt gacaaacttg ctcaagttgc tgaaaccatc aaaaacgctt aaggagttgc
    32701 tatgaaatta tccaacctac tgctatttgc aggagctaca gccggaagtt atctggttac
    32761 aaaaaatcgc caaaccatca cagatgaaat cttgaatacc actgaccgcg ttcaagctat
    32821 caaggacgat gtggatatta tccaaaacag cctgcaaatc atcgaccagc aaaaagaact
    32881 tatcaaggaa taccaagaag acttgactta caagtttaag atcttggaaa aggatatcca
    32941 gactagacta gctgtgataa aagaaatgca gggaactgaa gataagtaaa aagagccccc
    33001 ggctcttttt taaaacgtaa acaagttata gtgaattgaa tttagaatag cacatcatag
    33061 tttctaaagc attgttagag attactttaa aatcctctta tcaatttgtt catattctat
    33121 ttcaatctac tatatatatc ccatcaacta tgcatcataa tttaggtaac tcatactcaa
    33181 taaaaatcaa aaagcaaact agaaagctag gcacagactg ctcaaaacac cgttttaagg
    33241 ttgtggatag aactgacaaa gtcagctcaa aacactgttt tgaggttgtg gatagaactg
    33301 acgaagtcag taaccatacc catggcaagc cgacactgac gtggtttgaa gagatttttg
    33361 aagagtatca ttcaccattt cacaactaaa tcgaagactt tctgccgtaa tgaaaacacc
    33421 tgaaacagct tggtttcagc tgtccggaaa ctttaagact taggttcaaa gtttaggtat
    33481 ggaacttcga aggaggtcgc taccgtccgt cattacttag gaaagtctta aaaaatctat
    33541 aaagtaaaaa gagcccgaca gctctttttg tttatactca atgaaaatca aaaagcaaat
    33601 tagccacggg ctgctcaaaa cactgttttg aggttgtaga tacgactgac gaagtcagtc
    33661 acatatatac ggcaaggcaa cgctgacgtg gtttgaagag attttcgaag agtattattc
    33721 tccatcaaag gcatctttaa tatggtcaaa gaagcctttt ttctttggat ttactttcaa
    33781 gtcaccagca gccgcgaatt ctttcaaggc tactttttgg cggtcgttca agcctgtcgg
    33841 tgttacgaca ttaacagtaa cgtattggtc accaactgca ccgccacgaa ggctcggtgc
    33901 ccccttacta cgtaggcgga acttcttacc agtctgagtt ccctctggaa taaccaattc
    33961 aacatcaccg tgaacagttg gaatatctac tgtatcacca agagccgctt ggacaaagtt
    34021 gaggttgaga ttgtagaaga tagtcgttcc ttcacgttca aacttgtcgc tagcttccac
    34081 agaaactact acatacaagt caccataagg tccaccgtta aagcctgctt caccttgacc
    34141 agcgaggcga atttgttgac ctgtttccac accagcaggg attttcacat gtacgctatg
    34201 agcttgtttc tcatgacctg ttccatgaca ggttgtacat ggatatttga tttcttttcc
    34261 tcgaccgtga cagacatcac aggttacttg gcgacgcatc ataccaagag gagtctgcgt
    34321 atcgacgtta atgacaccag cgccatgaca gcgtccacaa gtgactggac tcgtccctgg
    34381 cttagcacca gagccattac atgtacgaca gccagcttca cgatgatact taacttcctt
    34441 ctcagttccg aagatagctt cttcaaaggt caaattgaca cgatactgga gatcatctcc
    34501 ttggcgagga gcgtttggat tgcgcgaaga accgcctccg ccgaagaaac ttgagaaaat
    34561 atcctcaaaa ccaccgaagc cacctgcccc attgaaaccg ccgaaaccac cagctccacc
    34621 aaaaccacca ttggcacctg cagcaccata ctggtcatag gcagcacgtt tttggtcgtc
    34681 actcaaagtc tcataggctt cttgaacttc cttgtacttg tcctcagcac caggctcctt
    34741 gttgatatct gggtgatatt ttttggaaag cttacgataa gcctttttga tttcgtctgc
    34801 cgaagcgttt ttggataccc ccagacgatc ataaaattca gtattgttca taattcaaga
    34861 tacaaagggc gtcaaacgga cacagccatc taggagtttt gacgacggac gcttacgtcc
    34921 tagagaaaac tatctttttg gcacagtccg tagcccgtgt tcagttacga acacccttat
    34981 tcctttctat tgatgttctg aatcgaacca ccatttaggt cggattcaat tcctttcttt
    35041 tatatttagt aagaaattct gaaacccgtg ttcagttacg aacactcttt gttcctttct
    35101 attgatgaga caaaacccaa acaaatgaga ttccgtccct ttttatcgaa aaacagaggc
    35161 tgggttgcaa cctctgcaaa taagtaaatt aactttattt tgattttaaa tatcctataa
    35221 gtacagaaat atttatatat ttttgtctct tcttagtatt tgctatataa ttccaattga
    35281 tcataagaaa tacaactact gtccaaatca caccaattat gaacggtatt acaaatttat
    35341 atgtttgtat ttctaatgat atcatagctg ataccagcgc cgatacaaat gcagacaaca
    35401 atactgaggt aacaaaattc cttaccgctt catcattttt gatacaacta tcatgttcag
    35461 ctaatataat ttctctatat ctagctaaat attctattgg aatattatca ataaaatctt
    35521 ttgatgttct atagttatca gcttgattac aaaaatcatt ataaactttt cgtgtatttt
    35581 ttagatactc ttcatccaat acactcgtct tacttttccg taaactctcc gtctacgacg
    35641 tcatcgcctg cgtttcctgt ttcttgtgcg ccttctgctc cttcttgagc ttgttgcgct
    35701 gctgcggctt gttcgtagag tttaacagca agtccttgag ctttttcgtt caatgcttca
    35761 agttttgttt tcatgtcgtc caagttgttg tcttcttgag ctttcttaag gtcatcaagg
    35821 gcagcttggg cagcgtcacg ttctgcgtcg aagcctttac cttcagtttc cttgattgtc
    35881 ttttcagtcg caaagattgc ttggtctact tcattacgaa ggtctacttc ttctttacgt
    35941 ttcttatcgg cttcagcgtt tgcttctgca tctttcatca tgcggtcgat ttcttcgtca
    36001 gtcaaacctg agttcgattg gatgacaata gtttgttctt tttgagttcc aaggtctttg
    36061 gccttaacag acacgatacc gttcttgtcg atgtcaaatg ttacttcgat ttgaggaatt
    36121 ccacgaggtg cagctgggat atcagtcaat tggaagcgtc caagagtctt gttatctgct
    36181 gccattgggc gttcaccttg aagaacgtgg atatcaacgg ctggttggtt gtctgctgct
    36241 gttgagaaga cttgtgattt agatgttggg attgtagtgt tgcgatcgat aagttttgta
    36301 aatactccac ccattgtttc gataccaagt gacaatggcg ttacatcaag aaggacaacg
    36361 tccttgacat caccagcaat cacaccacct tggatagccg cacccatagc aactacttca
    36421 tcagggttta ctgatttgtt tggttcttta ccagtttcag ctttaacagc ttcaacaacg
    36481 gcagggatac gagttgaacc accaacaagg ataacttcgt cgatttctga caagctcaaa
    36541 cctgcatctg aaagggcttg acgaactgga acttttgtac gttcaacaag gtcacgagtc
    36601 aaatcgtcaa atttcgcacg agtcaaagtc atttccaagt gaagaggtcc agcctcacct
    36661 gcagtgataa atggcaagct gatttgtgtt gaagttacac cagaaaggtc tttcttcgct
    36721 ttttcagccg catctttcaa acgttgcatt gccatcttgt cagtagacaa gtcgataccg
    36781 ttttctttct tgaattctgc taccaagtgg tcaatgattt tttggtcaaa gtcgtcacca
    36841 ccaagtttgt tgtcccctgc agttgacaat acgtcgaaga caccgtcacc caattcaagg
    36901 atagagacgt cgaatgtacc accaccaagg tcaaatacca atattttttc ttctttgtca
    36961 gtcttgtcca aaccataagc aagagctgct gcagttggtt cgttaacaat acgttctact
    37021 tcaagaccag caattttacc agcgtctttt gttgcttgac gttgagcgtc gttgaagtaa
    37081 gctggaactg tgataacagc tttggttact ttctcaccaa ggtagtcttc agcgtagcct
    37141 ttcaagtatt gaaggatcat agctgagatt tcttgtggag tgtattcttt tccatttgca
    37201 gaaacttttt cagaagttcc catcttagat ttgatagaga taactgtatc tgagtttgtg
    37261 actgcttgac gttttgcagc atcaccaacg atgatttctc cgtttttgaa tgagactaca
    37321 gatggagttg tgcggtttcc ttctgggttt gcgatgattt tgctttcagt tccttcaaga
    37381 actgcaactg ctgagtttgt tgtacctaag tcaataccga taattttaga catgtgtttt
    37441 tctccttgtt agttaatttt ctatttttct ttttgatact cttcttaagt ggcgacgccg
    37501 tcagagcttg acttcgtcag tctctttgac taaactttga gcctaaggtc tcaaaatttg
    37561 cgcaaatagc gccacggcga agagtatcgt ctttggttcg cttcgctcac tattacaaag
    37621 caaaacatat tttatctttc ttcatagttt attgtcgttt cggacaagtt ttctattatg
    37681 taaattgcga cacgaggagt cgaaatcgat tttatttcga cgacgagtta gtaaggaagc
    37741 taggcaaacg ccatagcaat tgccgttttc tgacgagttg ctttagctac cgtcagaatt
    37801 gccgaatcga acacgcccta agctctgagt aaaaatagga gattttcttg tgttcatcga
    37861 acacttcgtc aatctcctat ttttactgcg agctttttac gggctttgta tcttagttat
    37921 acaccactac cattgctggg cgtaggatgc ggtcatggag tttgtagcct ttttgaaaga
    37981 cttgggcgat ggtatctact gggtgttcat cgtctgctgg gagagtttgg atggccatat
    38041 ggtagttatg gtcaaattcg ccatctgctg cgatttcttc aattccttct tctttcaaag
    38101 cgtgaatcaa gctttcttgc accatcccca agcccttctt cacatcatct gtcaaacctt
    38161 caactgcaag tgcacgctca aggttgtcaa gagatggtaa gattgctttt gccaagtcct
    38221 ggctacgata acgttgcaag ttttgacgtt cttcattggc acggcgttgg atattttgca
    38281 tttctgcatg agcgcgaaga tatttgtttt cgaactcatc tgcacgttca tttgccaagt
    38341 ccaactcaga cttttcagga gttgtttctt cagctgtttc cacaacttcc tcttcttgaa
    38401 cttcttctac ttcttcattt tttatatctt gggccatgtt cgcctccttt aatgatttca
    38461 atcttaatgt acttcgtaat gattactgct gaggtagagg taaaaatctg tcaacttcat
    38521 ggtcaaaaca cggttgacca cattgacttg attgattagc tgttggtaat ccagattaac
    38581 cggaccgata atggctagaa ttccaactcc ccgataagga atgaggaact tactactaat
    38641 cactgctagg tcagctaaac aggattcttg accgtctgca acacgaacat tttgcatctg
    38701 atcctcacgc aacccctcac gaatctccaa ggccaccttt tgcggttggt caaagaactg
    38761 ataggctgct agattggcaa aattcaagag attaaccttg ccagccacca caatgttttc
    38821 gttgaacatt tccttaaaga tgtgttcaaa gagatcaatc acattatccg ttgttgtaaa
    38881 gtaacgctgg ataatctgcg gaatctccgt ccgaatcttg tagtgaatat ctaaaacagt
    38941 gtgaccgagg aaacgttcct gaatgattgc cttcagtttc agcaaatcct cctgcaagaa
    39001 gttccttgga atcagaaact gactagtaac cgttcgcgac tcgtctaggg taaataccgc
    39061 caaggctgta tgttgcccca aaacaacgat atcaaaggct gtcaaccgtt gcctgctcgg
    39121 ctcaacatcc agtgccacta ccgtacagcc actcaggtct gttagcaagt tagcagcctc
    39181 ttgcagaata tcctccaatt tgaagaattc ctgatcaaag gctttgacaa tctcatatac
    39241 ctcattttca gccagccggt caaaatccag tgagtgtttc acatagtact gaaaaccagc
    39301 aacacttggc atccgaccgc ttgaagtatg agccttctca agcaaccctt gtttttctag
    39361 ttccgccatg tcattacgaa tggttgcact gctagagtta atagactctt gcaaggcttt
    39421 tgatccgaca ggttcgtgcg ttttggtaaa gatgtcaata atcagattta aaatatcctg
    39481 ctgacgctct gtaaccatct catcactcct ctctgtctga tcaattagca ctcaaggcat
    39541 ccaagtgcta acttatgatt ctattataca cccttagaag agaatgtcaa gacaaaaact
    39601 caaaaaatta gcactctttt atcaagagtg ctaaaaatca atctgaagac ctagaacctt
    39661 gctattcatc tactcggtat ttccttttta gtctgaaata accatgaatt agataagaaa
    39721 tcagaaaagc atataaaaca aaaataagaa agaaagacat agaaagatct tctctaaacg
    39781 aactcataca aacaacaaga ccacctaaga aagtagctgt acaggaacga agtctagatc
    39841 gcataacttc ccatttgagc cccttactca tatagacttg atcctctgga agtaaatcag
    39901 aagacgattt acgaagaatc gaacaagaac ctgctcctat caattcccaa cctctatctc
    39961 taaaatcttg cagttcatgc ttatattttt taagaaatct agaatcatag atacggtaga
    40021 tgacatcgtc tggttgacct tgctcaaaat agaacaaacc aaaacaacta gttctatacc
    40081 tccaaccttt caaatgcatc tcatgtaaat actcttcttc cttatccaaa tcaacaatgg
    40141 tgaaaatccg aaattctact ctgctattca ttgtcctacc ccaaaattag aaaacatgcc
    40201 tggcgttatt tattagataa ttctttccac ttttgactca atctccaaaa aatataagaa
    40261 atctgaatcg caaaaactat caataaaacc caatctatta tgaaaatcaa aaatactccc
    40321 caactgaaag aactacctcc agtgacaaac tttgagaaaa ccggtaatag agctaaaaag
    40381 agaagcaaaa taggaagcat ccgcattgtt aaaatccgtt tggcataaaa aaatctttat
    40441 ttaaacgaaa atattatggc aaaatttacg ccagtttttg aacggctgat gtagatattt
    40501 tatactttca aaatgtttaa atgtgattat ttatttttga aaaatagctc accagcccga
    40561 ctgaaagtgc ttatagaatg ataataagtc gcctgccgaa aacagcgaaa aatagcggtg
    40621 ttatgcggag ataatctgac gcgatgcgaa agtatattgc atacttattt tcaacaattt
    40681 agcagagtat ttttataagt gtgatataat agaagtataa tttgttctga tagtttattt
    40741 tatggagaag tagattttta gaatgcggag ggttcaatat ggttgagttt ataaagtcta
    40801 agaaagaaat gagtgaggag gatattaaag caaatttcat cactcctgct attgtatcca
    40861 aaggatggaa aagtggtgag catatcactt acgaagaata cttcactgat ggtcgaattg
    40921 aggttagagg agataaggct cgtcgtaaag aaggaaaaaa atcagactat tcactgtatt
    40981 accaatttgg aactcgaatt gcaattgttg aggcaaagga taataaacac agcgttcgag
    41041 caggattaca acaagctatt gaatatggag agattttaga tgttccattt gtttattctt
    41101 cgaatggtga tggctttatt gaacacgacc gtatcacgag agaagaacgt gagctggagt
    41161 tagacgaatt ccctactcgt gaagaattat tttctcgtat gacgaaggaa aaaggattga
    41221 cgtacgaaat tacagaagct atctcaactc catactatac agacgccttc tcaatgaaaa
    41281 cgccacgcta ttatcagcaa atagctatca accgtactat tgaaacagtt gccagaggac
    41341 aaaaacgagt aatgtttgtg atggcaacag gaacggggaa aacgttcatg gcttttcaaa
    41401 ttattcatcg ccttcgaaaa gctggtttgg ctaaacgagt tttattctta gcagatagaa
    41461 acatcttagt agaccaaacg atggctgaag actttaggcc attcgaaaag gtaatgacga
    41521 aaattacacc aaaacttttg actgctcctg aaaaattaaa ttcttttgaa atttatctag
    41581 ggctttatca gcaactaact ggtgaagatg gaactgaaac acattatcaa aaatttgaca
    41641 aagacttctt tgatttaatc gtaattgatg aagcgcaccg tggttcagct aaggaagaca
    41701 gtaactggcg taaggtgatt gattatttca gttctgcgac acagattggg atgaccgcta
    41761 ctcctaaaga aaccaagaat gcttccaata cggaatactt tggtgagcca atctatactt
    41821 atagtttaaa acagggaatc gaggatggtt ttttggctcc atatcgtgtt atgagggtta
    41881 atttagatgt ggatgtggat ggttatcgtc cagaaactgg aaaagttgat gctaacggac
    41941 aattaatagg agataggtac tacggcagga aagattttga taaaaccatt gtcattgatg
    42001 atagaacgca aagagttgcc aagtttgttt ctgattatat gaagcaaaac aatgcacgat
    42061 ttgataaaac aattgttttt tgtgttgata ttgaccatgc cgagcgaatg cgtgctgcac
    42121 ttgtaaaaga gaatctagac ttagtccaag aagactatcg ttatgtcatg caagtaactg
    42181 gtgacaacgc tgaaggaaaa gctcaactgg ataactttat ggatgtcaat tctaattttc
    42241 ccgctatggt aacaacgtct aaattattaa cgacaggagt taatgctaaa acatgtcgtt
    42301 tgattgtttt agactctaat atccaatcca tgactgaatt taaacaaatt attggtcgtg
    42361 gcacacgtct ttatcctcaa aaggggaaag aattttttac gattattgat tttcgaaatg
    42421 ttaccaatct gtttgctgac cctgattttg atggtgagcc agtgaaggtg ctggaaacag
    42481 gtgcgaaaac agtcagtggt tctacgcctg gtttcgtagg tgaggaaggt gacccagtag
    42541 aaaaatatat cgttacagac aagcaggtta ccattcttaa ttctactgtt caagtattgg
    42601 atgaaaacgg gaaactgatt accgaaagcc tgaccgacta cactcgaaag aatatcttag
    42661 gtagctacgc cactttgaac gattttatca cagtttggca tacggcagat aaaaagaagc
    42721 ttatcttaga cgaactttat aaaaaaggag tttatctaga tgctattcga gagtcggagg
    42781 gaatatcaga acaagaaatc gatgattttg atttactcct aaaacttgcc tatggtcaaa
    42841 aagaattaac caaaacggaa cgtatcaata aactcaaaca aagcggatat ttatataaat
    42901 atagtgagga agcgcgtgct gttttggaaa ttttactgga caaatacatg gataaaggta
    42961 ttggagaact cgaaagcatt gaaacattaa aacttccaga atttcagata tatggtggaa
    43021 ccttcaaaat catcaatact tattttggag ataaaaaacg atatttacaa gcaattaaag
    43081 aattggagca agagctattt acagtagctt aatgaaagga aagtatgtca attacatcat
    43141 ttgtaaaaag aattcaagat atcactcgaa acgatgctgg tgttaatggt gatgctcaac
    43201 gtattgagca aatgtcttgg ttattattct taaaaattta tgatagccgt gaaatggttt
    43261 gggaattaga agaagacgag tatgagtcaa ttatcccaga ggaattaaaa tggcgaaatt
    43321 gggctcatgc tcaaaatggg gaacgggtat tgacaggcga tgaattactt gattttgtca
    43381 ataacaagtt attcaaagag ttgaaagagc ttgaaataac ttcaaatatg cctattcgaa
    43441 aaacgattgt taaatcagct tttgaagatg cgaacaacta tatgaaaaat ggcgtcttgt
    43501 tacgccaagt catcaatgtt attgatgaag ttgatttcaa cagccctgaa gatcgtcatt
    43561 cgtttaatga tatttacgaa aaaattctta aagatattca aaatgctggg aactcaggag
    43621 aattttatac gccacgtgca gcgactgatt ttattgccga agttcttgac ccaaaacttg
    43681 gagaatcaat ggcagacctt gcttgcggaa caggaggctt cttgacttcg actctgaacc
    43741 gtttaagtag tcaacgtaaa actagtgaag atacaaaaaa atataataca gctgtttttg
    43801 gtattgaaaa gaaagcattt cctcatcttt tagcagttac aaatctgttt cttcacgaaa
    43861 ttgatgaccc taaaattgtt catggaaata ctttggagaa aaatgttcgt gaatatacgg
    43921 atgatgaaaa atttgacatt attatgatga atccaccttt tggagggtca gaattagaaa
    43981 caataaaaaa taactttcca gcagaattac ggagttctga aacggctgat ttatttatgg
    44041 ctgtcattat gtatcgtttg aaagaaaatg gtcgtgttgg agttatttta cctgatggtt
    44101 ttctatttgg tgaaggtgta aaaactcgct tgaaacaaaa actggtagat gagttcaact
    44161 tgcatacgat tattaggttg cctcatagtg tctttgcacc gtatacagga atccatacga
    44221 acattctttt ctttgataaa acaaagaaaa cagaagaaac ttggttttat cgtttagata
    44281 tgccagatgg ttataaaaat ttctctaaaa ctaagccgat gaagtcagaa cacttcaatc
    44341 ctgttcgtga ctggtgggaa aatcgtgaag agattctgga aggtaagttc tacaaatcta
    44401 aatcatttac acctagtgaa ttggctgagt tgaattataa tttagaccag tgtggttttc
    44461 caaaagagga agaggaaatc ttaaatccct ttgagttgat tcagaattat caagcggaaa
    44521 gagcggcttt aaatcataaa attgataatg tattagctga tattttgcag ttgttggagg
    44581 ataaataatg acaccagaac aacttaaagc aagtatcctt caaagagcga tggaagggaa
    44641 attagtgccg caaaatccca atgacgaacc tgcaagtgaa ttgttaaaga gaattaaagc
    44701 tgaaaaagaa aaacttatca gtgaaggaaa aatcaaacga gataaaaagg aaaccgagat
    44761 atttcgtggt gatgatggga aacattatgg gaagtttgct gatggaagca ctcaagaaat
    44821 tgatgttcct tatgatattc ctgatacttg ggagtgggtg aggataaaat caatttattg
    44881 gaattttggg caaaataagc cagagaaatc ctttaggtat atagatacgt ctagtattga
    44941 tagaaaaaag aacataatca actacaaaaa tctacaatat ctttcacctg aacaagcgcc
    45001 ttcccgtgct agaaaattag tttcgcagaa tagtgtctta ttttcaacag ttagaccata
    45061 tctaaaaaat attgctgtag ttagagaact taaagagtat ttgatagcta gtacagcatt
    45121 tattgttttg gatactttac ttaacgaaac atatttgaaa tattatttat tatcagataa
    45181 ttttatcaat cgtgttaata ataaatctac tggaacaagt tatcctgcaa tcaatgatta
    45241 taattttaat ctattattaa ttgctctctc cccactatcc gaacaacaac gaatagtaga
    45301 agcaatcgaa tcagctttag aaaaagtaga tgaatatgct gaaagttata atagactaga
    45361 acagctagat aaagaatttc cagataaact aaaaaaatct attcttcaat atgctatgca
    45421 aggaaaatta gttgaacaag acccaaatga tgaatcagtc gaagttttac ttgaaaaaat
    45481 acgagcagaa aaacaaaaac tttttgaaga aggcaagatc aaaaagaaag atttagagat
    45541 ttcaattgtt tccaaagaag atgataactc ttattatggg aatataccta tgaattgggt
    45601 tgttataaaa ataaaagata ttttttcaat aaatacaggt ctttcttaca agaagggcga
    45661 tttaagcatt aataataaag gtattagaat tatacgtggt ggtaatatta agcctttaga
    45721 attttctctg ttggataatg attactacat tgatacacaa ttcatctcct ctgagcaagt
    45781 ttatttaaaa cataatcagc taataacacc tgtatcaacc tctttagaac atattggaaa
    45841 gtttgcaaga atcgataaag actatgatgg tgttgtggct ggtggattca ttttccaatt
    45901 aacaccattc gaaagttcag agattatttc aaaatttcta ttatttaact tgtcctctcc
    45961 gttattttat aaacaattga aagcaataac taaactatca ggtcaagctt tatataatat
    46021 tcctaaaact acactaagcg agctattaat tccgttagct ccttttgagg aacaggaact
    46081 tattactcaa aaaattgaga aactttttga aaaagtaaat caactttgga aatgattctt
    46141 ttcatctctt catgattaga aatagggatt aataattcgg agatactggt actatttaat
    46201 gttttccctt tgatagcatc ttttgaatca cctaaagtag agataagtgg caaaaatatc
    46261 attaagtaat ctctgataat attttcttta ttagcatagg ggaatatcga tataatggct
    46321 tcattatgag tggcaggaat atccaatatg gcaacttttc caatagataa tttaaagctc
    46381 attaataaag ttcctttagg tgaaatgtct attttctttg attttaatgc taatttagaa
    46441 atagattctc tcgtattagt tacataacca gatataggca tatctgatat agatacccag
    46501 ggtatttcag ttccccaaaa agtagcttca ctgcgtggag gagtttttcc tattctgaag
    46561 ttaactaggc tagcaaattt aatatatctc catgcttctg ggatttcata tataggataa
    46621 gaggatgttt cgtctttgtt cccataataa gagccataat cacaaaaata gcaggtagtc
    46681 agtttgacca cctgttattt tttaccaatt aacaatttta tctacaatat tttgttgttc
    46741 agtagctgtt ttccttagat aaattcgagt agtttctata ctttcgtgtc ccatcaaatc
    46801 tgcaagcaag gcaatatcat tatacttcgc taaaaaattc ttagcaaata aatgcctaaa
    46861 agaatgaggg taaattactt taggattcat tttgtattta tcagcataat tttttaactg
    46921 ttgagcaact cctcttgctg taattggttc gttaaattta ttcaaaaata aataaccact
    46981 tcggcgattt tctgattcta accaactaag acaactattt cttaattttt taggaatgta
    47041 cagtctacga attttaccac cttttgagta aatgtcaaaa taaccgattt ctacatgctc
    47101 tacttttagt ttaataagtt cacttacacg agccccagtt gcacctaaaa accaaacgac
    47161 aaaatgccat tttaaaatac catctttttt caaactacgt ttaagaaaaa ggtaatcagc
    47221 gtggctaatg acatcttcta aaaacggttt ttgctgtact ttgacaaatt ttaatttcaa
    47281 atcatcatga ccaataaaag tcagatattt atttactcct tgtagtcgca aattgacagt
    47341 tttaggttta aaattgtcta ataaatatcc tttgtattca aataaatctt ccattttgag
    47401 ttcgtaattc tccaagaaaa atcgaacacc ataaaggtac gaacgcacag tattttcagc
    47461 taaaccagct ttcttcaaat gtaattcaaa atctttcaac gtaaaactcc tatcttatgt
    47521 ttgatagaaa ttccaccgca cgtaaaacta ttatactaaa ttagtgcgtc aatatgggcg
    47581 aaaaattgtt cgattttatc aacgattctg gattgttcag gaaggggtgg gagggggatt
    47641 aaatattctt ttatagtttt cgttaataat tctttttgtt ttgtactacc cgacgctttt
    47701 tcttcaataa ctgactgaac aataggagag gaaagaaaat tatagatgaa atggcaatta
    47761 ataactcccg ataagactct tataactgta acatggctat ctgcaacagc ccagccataa
    47821 ggatttttat tttcatggta aatagctaat cgtcctaacg tacctagacc tgttgaattc
    47881 cacattaaat caccatctct tagtaatctt tctttctggt aactatgaac tgtttcggga
    47941 tcaataaatc ttgctaagtc aatagaaaag ccagaccatt gattacattt ctgagcaatc
    48001 acagggtata taggaatatt tgaatatttt ggagacttcc ctctttgaat gtaggaggtt
    48061 atatcgttta acctcaccca ttcccaactt tctggtattt cacaaggtac ttcctcataa
    48121 taagagctat catctccttg ggaaacaata gaaatgtcca aatctttctt tttaatcttg
    48181 ccttcttcaa agagtttttg tttttctgct cgtatttttt caagtaaaac ttcgactgat
    48241 tcatcatttg ggtcttgttc aactaatttt ccttgcatag catattgaag aatagatttt
    48301 tttagtttat ctggaaattc tttatctagc tgttctagtc tattataact ttcagcatat
    48361 tcatctactt tttctaaagc tgattcgatt gcttctatta tgcgttgttg ttcggatagt
    48421 ggggggagag ggataagaat agaagcaact ttatcactat tcaagttttt cacaacagct
    48481 ccactaatta gagatagaaa ttgagaataa actacatttg atgaaagaat atagaatagg
    48541 taatctttat ttaatgagtt ttcatagttc gaaatagcca accatccatc gtgtattgca
    48601 ccatcaacat tcaaaatata aggtctacca aaactcatag aattagttaa caaaaatgta
    48661 ccttttttta caaatctagt tttgttaagc cctgattttt tgattttttc tttaacatta
    48721 tttatatact tttcaccctt ttcagtatca cctattttta tccaatttat tccatctact
    48781 tcagaagtaa gataatcttt gattggtcgt ggagagccac ctctgacaat ttcaaccaat
    48841 gtagaaaacc tcacccactc ccaagtatca ggaatatcat aaggaacatc aatttcttga
    48901 gtgcttccat cagcaaactt cccataatgt ttcttatgtg cttcaagtat ataaaaaggc
    48961 gtaaaaatac gcctatagat aatggggttg aaataggttt attgttgatg agattgtaga
    49021 taattcaatt ttttacttcc aatcgaatat tcaaaacctc caccttttct gcctgtaatt
    49081 gttcatcata aaattcaata tcttcaggat tttccccttg gcaacctcgg cagaaatatt
    49141 cttccgctcg atcaggattc aaaaatcgac aagcacaaac aaaacagtcg ccatcatcat
    49201 ttattgagat aatatagtag attgaaataa gatgtaaaca aatcgattag gaaagttaaa
    49261 ttagtttcta gaaattttta gcagatgtag tgtactattc tagtctcaat ttactatggc
    49321 ttcaaatata tctttcgaaa aaatatttac agatgtgtaa ttttgaagct tgcaaaagtt
    49381 agtaaacttg tagatttcga tttgaagtaa cttgttttct tgcccgatat tgtttttaaa
    49441 attgaatttt tccatagtga ctccttgatt ttcttctaca cgtctgatga taaatctaat
    49501 ttgcaaaaga gtcaagagga tttttcgaaa aataaatagc gaccgaaatc gctattttaa
    49561 gggttatagg tatttgatgg cttagactgc tgtgtgactg tttacccaca ggcaatcttt
    49621 cttctatatt agtattagta aaggtctaaa taattatcaa tttcccattg tgaaacaaag
    49681 gttgcataac ttgcccattc gattcgtttg gcttcaagga aactagtata gatatgttct
    49741 ccaagagccg ctctgacaac ttcatcttct gtcaaagctt tcaaagcgtt atgaagagtt
    49801 gatggaaggt ctgtaatacc agcttcctta cgctcttctg ctgtcatgat gtagatattt
    49861 tcttcgatag gagctggtgc ttcgatttta ttttcaatac catgcaaacc aacctccaac
    49921 agaaccgcca tagcgatgta agggttcgcc attggatcca ctgaacgcaa ctcaagacga
    49981 gttcccatac cacgtgaagc aggtacgcgc acaagtggcg aacggttacg accagcccaa
    50041 gcaatgtaaa caggcgcttc ataacctgga accaaacgtt tgtatgagtt aactgttggg
    50101 ttcatgatag cagtatagtt gtaggcatgc ttaatcaaac cgccaagaaa atggtaggct
    50161 gtttctgaca actgcattcc ttttggatca tttggatcaa agaaggcgtt atttccttct
    50221 gcatcaaaca aggacatatt acagtgcata cctgatccag caataccaaa ttttggtttc
    50281 gccataaagg ttgcgtaaag cccatgtttg cgagcaatgg ttttaacaac gagtttaaag
    50341 atttgaatct tatcacaagc acggagaact tcatcatact taaagtcaat ctcgtgttga
    50401 ccaaccgcaa cctcgtggtg actggcttct acttcaaatc ccattttggt caagacattg
    50461 acaatctcac gacgtgtatt gtccgcaagg tcagtaggcg ccaaatcaaa gtagccaccc
    50521 ttgtcattca cttcgagcgt tggatctcca ttttcatcca gtttaaatag gaagaattct
    50581 ggctctggac caaggttgaa agatttgaat cctacttctt ccatatgacg aagagctcgt
    50641 ttcaaattac cacgagggtc ccctgcaaat ggttcacctt ctgttgtata gacatcacag
    50701 atcaaacctg caacacttcc attttcatct ccccaaggga agactgtcca tgtatccaag
    50761 tcagggtaca agtacatatc cgactcattg atacgtacaa aaccttcaat agaagatcca
    50821 tcaaacatag ccttgttcga caagacctta tctaattgtt catctgtagc aggaatttcg
    50881 acgtttttca tggttcccaa aatatctgaa aacatgagac gaataaaggt aacatttttt
    50941 tccttgactt cacgacgaat atctgcagct gtgattggca tgagttttct ccttaatgta
    51001 tgactacttg cggttgccta accgcgacca aaaggtgact gtactgaagc aaagcgaccc
    51061 tgttggagga gttcattgtg aagtgcacgg cgcacctcag tctgactcac cgctttcttg
    51121 gatttcgctt cacgttcagc atattttttc ttaatggcag cgatattata accttcagag
    51181 atataatctt tgatttcaag cagacgatcc atgtcattca aggaatacat gcgacgattt
    51241 ccttcgtttc gatcgggctt gatcaactct tgatcttcat aataacgaat ctgacgcgcc
    51301 gatagatcgg tcaacttcat aacactgccg ataggaaaaa cagccatatt tcggcgaaat
    51361 tctttttcct tcatttacaa tttccttctt tctgtctatt atagtctaaa aaaagacaaa
    51421 cgtcaattaa taatgttata aaatgtaaca ttatttttct tttttctcta agaagagacg
    51481 aatacgatca atatcgtaat ttacgataat tgcgacaaaa actcccataa acgtttctga
    51541 tacacgcaca aacacgtacg aaattgtctc accacttgga attgataggg taatgattaa
    51601 catagctgct acaccaccaa taactcctgc tttgttgttc atggctacat ttgtcataat
    51661 ggttaacatg gtgcagattg gaacaactac caaggtcacc caaaaggctt cgtggaaaaa
    51721 ggtatttaat aagaagaaga ccaaggcata gagtccaccg atactatttc ctagaatacg
    51781 cgaagtccca aaatgaacac tcttatcaaa actctccctc aggctaaaaa cggctgtcaa
    51841 agcaccaatt tgaagacctt tccagccaaa aaatccaaaa atcaagagaa ctagaaaaac
    51901 agcaatacct gttttaaagg ttcgcatacc aagtttaaac tgggatttat cgaatttata
    51961 ttttttaaaa taactcataa tctcaacttt ctatttccat tttatcataa atcggtgatt
    52021 tttatgagta atagttgaga ggaagcgttt ttattttaag caaaagaaaa gaggaacttt
    52081 catccctctc ttctttgatt tgtttataaa atcttatttt tctgtcaagg ctgcaagtcc
    52141 tggaagaacc ttaccttcaa gaagttccat tgatgctcca ccacccgtac taatccatga
    52201 gaacttgtct gcacggccaa ggttaatcgc tgcggcagct gagtcaccac caccgatgat
    52261 tgatttaact cctggttgtt tcacgatagc gtccatcaca ccgactgtac cagcttggaa
    52321 atctgggttt tcaaatacac ccataggtcc gttccataca actgttttgg caccagtcaa
    52381 agcttcgtca aatttggcga tagattttgg accgatatca agaccaagga agccttcaga
    52441 aactgcttca ccttcagtgt cacgcacttc agtgtaacca gcaaatgcgt tagcttcttt
    52501 tgagtcaact ggcaagatca atttaccatt tgctttttca agaagagctt tcgcaacatc
    52561 caatttgtct tcttctacaa gtgagttacc aatttcgata ccttgtgctt tgtagaatgt
    52621 ataagtcatc ccaccaccga taaggacttt atcagctttt tcaagcaagt tttcgataac
    52681 accgatcttg tctgaaactt ttgaaccacc aaggatagcc acgaatggac gttctggagt
    52741 ttcaactgct tcttggatgt aggcaatttc gttttcaaga aggaaaccag caactgcttt
    52801 ttcaacgttt gctgagatac caacgttaga tgcgtgtgca cggtgagctg taccgaatgc
    52861 atcgtttacg aagataccat ctccaagtga tgcccagtat ttaccaagtt caggatcgtt
    52921 tttagattct ttcttgccgt caacatcttc gtaacgagtg ttttcaacca agagaacttg
    52981 tccatcttca agagcgttga ttgccgtttc caattccgca ccacgagtga cacctgggaa
    53041 aacaacatct tgaccaagtt ttgctgccaa gtcagctgct acaggagcaa gtgatttacc
    53101 agctttatca gcttcttctt tcacacgtcc aaggtgagag aaaagaattg cacgtccacc
    53161 ttgttcgatg atgtacttaa tagttggaag agctgctgtg atacggttat cgttagtgat
    53221 tacgccatct ttcaatggta cgttgaagtc aacacgaacg aggacttttt tacctttcaa
    53281 gtcaacgtct ttaacagtaa gttttgccat gttacaaaaa ctcctttatt tattttattc
    53341 gaaactatta tatcatactt tggaaatata aggaaagatt tcacaagatt tttcgatatt
    53401 taatctttat cttctctttt ccgtctcaag gtcaaggcta aactagcaag accaaggctg
    53461 accaagcctg ctattaggga ttcattagca tcagctgttc ctgtatttgg caattgtttg
    53521 cttgcttctt ctgatttaac tgctgtattt tgagctggtt tttcctgtgt agctactact
    53581 gctggtactg tttttacttt tgttccaatt tcaacaattt ctggaatcgc ttcttggatg
    53641 acttctgttg aacgaagacg acgctgaccg ttttcatcaa cttcaaagac atgtcttaac
    53701 agtccatctc gtccctgtat gatgactcgt tgttccccaa ctagcatctc agcattttca
    53761 tgctcttgac gatgaaaggc aaccttttcc tcttgaactt ccaatttagg agccttttgt
    53821 tgatcagaag ccggttgata agtaggtttt ggaaggactg tgttttgtgg tgctggttta
    53881 gcaggttgtg gtttttcagc agattcataa acaaaggcat aatgagtaaa gtgtggtgct
    53941 gtaaagataa catgactatc cgtttgttca aaagccaatt ctactgcctc tttgccttca
    54001 ggtaagaaaa atactttctt aactttctta tctttttcaa ttgggatttt cacaatagaa
    54061 gcgtaagaga gatcaacatc ttgacctttt tcatccaaac cttctatttc aaagacatga
    54121 gcatcttctc cagcaaagta tttcttctct tcagcacttg cttgaacacg ctctactttc
    54181 aaatccttga tgacagtctt ctctttattt gagaagtgta cttcaacacc tgttttacta
    54241 tcagaaaaga ctgctggctt gtcttctttc aataaagcaa ccagatcttt tagactctgt
    54301 ttcgctgttg caagctcttc tggactcaaa tctacttttt caaccaaggc cttgttcttt
    54361 tcaagaagcg gagctagggc agaacctgaa ggatggtttg gcagccaaga gttcttgagc
    54421 ctcacctgtt aagcgatcaa gctctgtctt ttcttccata aatttctctt gaccattcag
    54481 agctttatga gcttctgtca atttattaag tcggtcattg acttgatctt gggtgctagt
    54541 ttcatggtct ttcaacactt gttcggccgc ttcaattgct ttcaagaaag cttcttttac
    54601 ttctggtgaa gcaaagttat agaccacctt gttcttagca gcttcaactt ctgctaattt
    54661 ttgtttgagg tactcatcgt tcaatgctgc ttttggagat accaaaacat caaagttgac
    54721 ttcatgacct tggtaacgaa gcgtcaaggt ttgacgacca gtcttttgag catcgtaacc
    54781 agaaatttca actccctcat cagtaaagga atgttcttcc atggtgtcat tgctataagc
    54841 cactgcaaag cgtccttcag acaagtctaa gctatcacca actaggtaat cttttttcgg
    54901 ttcctgactt acttcaattc ccaaaatagt tttcggactt gcttcatctt ggccagtgac
    54961 agtcactgac aaattagcat ttactggttg tcccaaatat tggagagtaa gattctgttc
    55021 tcccttatga tgcgtatcaa aacctgatac tgatacacct gcgtgattta gacgaatgag
    55081 ttcgtcctca gttcctcctt catactgaac tcgaagaaca ccacctctaa ggtccaaatc
    55141 ctccccttcg gcgtagctta ttttcttagg tcctgtttct aggctgacta acttgattct
    55201 tctgccatct tttggaacgg aaactgctag gacattacta atttccttgc ctggcaactg
    55261 ggtacgataa taaagaagac cagattgatt tgtcaaatcc aatggtgcac ttgctaggtc
    55321 tcctccaact tcgctcttca aggttgcgag cggagtttga gaatttggat tatcataaac
    55381 ggtaatagtt gctccagccg gtacatctgc aaagccaact tgtaccttgt tattgcctag
    55441 agaacgggct gcagccttgg ccatcggaat atttacactc tcagtatcaa gcttttcata
    55501 cattttccag ttatagatac gaatagcctt ccatggagtt ccattgtcag aagtgacaac
    55561 attcaagtac cagtcttgag cagtgattgg tttatcaaga gtgatatctg tcacatgtgc
    55621 tttgttacca cggacttcct tagctagctt ccactcacaa tctgcatctt tataataaag
    55681 gtcaaagtct ttggtgttca tcaagccatc gttaacagac tcaccaccag cccctgcatg
    55741 atccatgacc catctaacaa cggtacgtgg cttggtcaaa cgaatatcca cactaccact
    55801 caactgagct gaagaccatt tatctgacaa gctagtaatg gtaccgttca acataccttc
    55861 aataccttct ccaccttcag tcttagggaa agtactatca ataactgttg cacctggaac
    55921 gatattttca gctagtggtt ttggtaggct ggtatctttt acagtcatac cccaatcaaa
    55981 ggttgtggtt gcagcttctg aacgaactcc atttttaccg actgctacaa ccttcagttc
    56041 ttgagttgta ccctgagcac ttgctgagcg gctaactttt ggtagataaa tagttgtaga
    56101 agatgagcca gttagtaatt tccagctgtc tccatctttt tcataaactt catagaaatc
    56161 tgcatccttg ttgcctttaa attgcacaac tgcttccgct tcttgggcat ttttaagcga
    56221 ttgtttcact acagaaaagc ttgttggcga ttgtggctct tggtgattgt ccgagatagt
    56281 taattgtccg aggttgaact gataatcttt tacagcacct tcatgctcga aaaatagttt
    56341 gactgcatag atggttttac ctgctagtga gctgagatca aattcttcat ttgtccagtt
    56401 gtcagaaagg gttagctctt tccatgcatc tgcatcatcg aatttgtagt ctggagttgt
    56461 agagaatgcc atataaactt tagaaccttt tcctctcttg tgggcaacac gaagtttggt
    56521 cttctcagtt acttctaact tagtagaata aagtctcaca tcctgatctg tcttaccggc
    56581 tacatcacca gagaatttaa gggaatttcc gccattatag gcatctgtaa aatcatattc
    56641 tgcacgaagt ttttcccctg ttgaagtctg ccaccagcgc catgttggaa gaacacctga
    56701 tactgaacga taattccact cagaatcctt agaaacctta ccatctacga accatttttt
    56761 accatgacct gtattaaaag aagtagtaaa agtattacct accgctggcg tacggtccgc
    56821 aactaggtta gcaataccat accaatcttt gtcacctggt ttttggccag tagggtctcc
    56881 ttgataacct gtaaagaaga tatcttcatt tttatgataa tcttcaccag tttttcctaa
    56941 acttgtaatg gtatctgggg caaataaacc aagagaaagg cgcaatttcc cattttcgtc
    57001 taaaatgtca ttccacttaa cctttgtctt gtaggaacca ccctgttgca attccaaacc
    57061 tgcaaataca tcataaggat tacgaccaat ccagttggca gttgcaatag tgtaatcatt
    57121 tttagcctta tcccagttaa agttagcaaa gaagttatct gccggaacct tatctccttc
    57181 tggttgcatg aattggtagt tgtattctcc caaaccatct tgatggtaac gtccataatt
    57241 ataggtcatg gcatcatacc aagaatactt gattggatgg tttaccttag cagcatattc
    57301 cttgctatag agcataaact ggcgcatctt ttctccaaga ggtttaacca aatctccagt
    57361 tgtttcttgg ttgatgaaat agccatcata gccataatac ttggccatgt ctaccaattt
    57421 acgggcaatt gggaagctac catctgcgtc ttgcttcaaa gcttcagcaa atctttcttg
    57481 atctgcaata ctattagacc agttgaagaa gagtgtaccg tatacaggaa ccccattacg
    57541 gtgacctgca tcaataacgt caggagttgg tacgagacct tcccagaaaa ccattgaatc
    57601 tagatattgc caatagtcaa aagcataggc cttgaactct tctccaccaa cagaagcatg
    57661 gtcttttgct ttagaattgg tgtttgataa ggcttgaact tttgcttcct tgctagcttt
    57721 ttcattgact aaatgacctg tccgacgtga agcgaggata acagatccgc ggttaatagc
    57781 atcatcttca cgagcacctg gttcccattt taacaattct tcccaagaat taaatttgat
    57841 ttcctttggt tttaatgttt tttctgtatt tttagggaca tctggctgga cttctttttc
    57901 agtcttatta gcttctgctg ctggcttaga ctcatcccct tggttagttg cttcgggctt
    57961 tgcttctgca gatggtgttt ctgcaaccac ctcacctgct ttttcctctg gtttagctac
    58021 gctagctgct tctgcctttt ctagcttgtt ttctctagca tgttcccctt cattctgctt
    58081 atcaacttca ttggtcgaat gctcactctc tcctgaaaca agctctgtat tagctccgct
    58141 attttcagga actgcagttt cttcagccaa ggctggacca gcaaataaaa cagcaccaat
    58201 catcagcgag caggctccta ctgataactt acgaatactg taacgacaac gtctttcaaa
    58261 aaatggattc ttcattttct cctcctaaaa gattgatttt gttgttttca agaaagcgct
    58321 ttatattctg tagtttttta actctagaac catgataatc acatttttat cctaaaacat
    58381 ttttagacaa aaaacaatag ctgttttcac aaatctaaaa taaggttaaa aactcttaaa
    58441 aataatacac ttatcaatta taattttctt ttacaaactt gacattaaca cttgttagat
    58501 ttacttttat cctttaaaat agaataggag atattccgcg attatttttc ggaggaaaaa
    58561 gaaatgtcca ttaattggca ggaaatttta tttcactttt taggtggtct ggggctattc
    58621 ttatatagta tcaagaccat gggagacggt ttgcaacaag ctgctggaga tcgccttcgt
    58681 ttttacattg acaaatatac tagtaatcct ttctttggag ttctggttgg tattgggatg
    58741 actgctctaa ttcagtctag ttctggtgta acagttatca cagtcggcct ggtcagtgcc
    58801 ggtctcttaa ccttacgtca ggctatcggg attgtcatgg gtgctaatat tgggacaact
    58861 gtcacatcct ttctcatcgg ttttaaatta ggtaactatg ccctacctat gctctttatc
    58921 ggtgccgtct gtctcttttt tacaaaaaat ggacagtcaa taatatcgga cgtatcctct
    58981 ttggtgtcgg tggtatcttt tttgccctca atctcatgag cggcgcaatg actccactca
    59041 aggatttaca ggtctttaag gactatatga ttgagctaag taagaatcct gttttgggtg
    59101 tctttgtcgg taccggcttg accttgctaa ttcaagcttc ttcggctacc attgggattt
    59161 tacaaaacct ctacgccggc aatctaattg acctacaggg agctttgcca gttctatttg
    59221 gtgacaatat cgggacaacc attacagcca tcattgcctc tttaggggct aatattgcag
    59281 ctaaacgggt agcaggagct catgttgcct tcaacgttat cggaacagtc gtctgcgtta
    59341 tttttctagt tccttttact gtcctgattc attggtttga agctacgcta aatctagcac
    59401 cggaaatgac catcgccttt gctcacggaa cctttaatat taccaacacc attgtccaat
    59461 ttccatttat cggagctctg gcttactttg taaccaagat tattcctgga gaggacgagg
    59521 ttgtcaaata cgaaccctta tatcttgatg aacatttcat caaacaggcc ccatctatcg
    59581 ctctaggaaa tgctaagaaa gagctcttgc acttaggaaa ctacgctgct aaagcctttg
    59641 acctttccta taagtacatc attgacttgg atgaaaaagt tgctgaaaaa gggcataaaa
    59701 ccgaagaagc aattaacacc atcgatgagc aattaacacg ttatctcatt gccctttcaa
    59761 gcgaagctct cagccaaaaa gaaagtgaag tgcttaccaa tatccttgat tcctcccgtg
    59821 atttggaacg gattggagac cacacggagg ctctactcaa tctgactgcc tatcttcaac
    59881 ggaaaaatgt tgaattttct gatgccgcct tgaaagaatt agaggaagtt taccgccaaa
    59941 ctagtgactt tatcaaagat gctctggata gtgtggaaaa caatgatatt gaaaaagcac
    60001 gcagtcttgt agaacgtcat gaaacaatca ataagataga acgtgttctc agaaaaaccc
    60061 acatcaaacg cctcaacaaa ggcgaatgtt caacacaagc tggggtcaac tttatcgaca
    60121 tcatctcaca ctacactcgt gtatcagacc acgctatgaa ccttgctgaa aaggtttttg
    60181 cagaacaaat ctaagaacca agaagctatc catcataatt ggatggcttt ttactttttt
    60241 ctaagcaaga ctaggctgaa tgaaactgaa agagtattct acagatatat agtatattga
    60301 aactagaata gtacacctct atttctaaaa cattcttaga aatcgatttg actgtcctga
    60361 acgatttgtc ctgttattat ttcattttat tatagtggat taaattaaaa aagtatagta
    60421 tattgaatct ataacagtac atcttgactg ctaaaatatt tctataaatt aatttgactt
    60481 tcctgataga gatgttcaca tcttatttca attcactata caatccagtt cctaaaactt
    60541 tgctagaaat tgatttggct ttccgaatta atttgttcaa attttatttc atttcaatat
    60601 actgataaat ccattcacta gcacagggca agagggagtc gctattgatt tcaagggtag
    60661 caggtacata cagaggactc ctacctcaga tatactgcaa tatcatcgta tgcaaaaaac
    60721 ctctgagatt tttctcaaag gttctgattt tgctaattgc tgttctcaac cgctgcagta
    60781 acaaaggcag tgtagagttc ttctggtcgg tttggacggc ttgacagttc agggtgatac
    60841 tgacaagcta caaagaattt attttcagga atttccacga tttctaccaa acgattgtct
    60901 ggagaaactc ctgaaaagac aaaacctgct gcctcaaact gctcacggaa ggcattatta
    60961 aactcataac ggtgacggtg acggcgttgc accacttctt gattgtgata agcagcagca
    61021 gccttagagc cacgtttcaa cttagacgga taaagtccca aacgaagggt tccacccata
    61081 tcctcaatat caatctgatc acgcatgata tcaatgatag ggtattttgt ttctggtgca
    61141 agctctgcag aattggcacc ttcaagacct aaaacgtgac gagcaaactc gatacatgtc
    61201 aactgcattc ccaagcagac tcccaacatt ggaacatcat tttcacgcgc atagcggatg
    61261 gcttggattt tcccttctgt accacgttga ccaaaaccac ctggtacgat gatcccgtcc
    61321 gcatcagaca agagttctgc tacattctct gctgtcacat cattggcatt gacccaattg
    61381 attttaactt ctacatcatt gacatagcca gagtgtttca aggcttcgac cactgagata
    61441 taggcatctt gcaactccac atacttacca acaaggaaaa tcttaacttg tttcttgagg
    61501 ttcatgacct tgtccaccat ggctgaccat tctgtcatat ccgctgctgg tgcgtctaat
    61561 ttcaaatgat cacaaacaat ttggtccatc ccttgtgcct gcaagttcag tggaatttgg
    61621 taaaggtgtt caacatccaa cgattcgata acggcttctg gtgccacatc acagaactgg
    61681 gccagtttat ttttaattcc ttgaccagct ggctcttctg tacgaataac caacatattt
    61741 ggttggattc ccaagccacg caattctttg acagagtgtt gggttggttt ggttttcatt
    61801 tcaccagcag ccttgaggta aggaagcaag gttgtatgga tatacatgac attatccgca
    61861 cccacatctg ccttcatctg acgaagagcc tctaggaatg gcaaggactc gatatctcct
    61921 actgttccac caacctctgt gataatgaca tcagagtcgg tcgttagagc ggcacgcttg
    61981 attttttctt tcaaagcatc tgtgatatga ggaatgactt gaacagttgc cccaaggtat
    62041 tctccacggc gttctttacg aagaacttca ctgtaaattt tcccagttgt cacgttggaa
    62101 tatttgttga gattgatatc gatgaaacgt tcatagtgac ccaagtccaa atctgtctca
    62161 gctccgtcat ctgtcacaaa aacttccccg tgctggtaag gactcatggt tcccggatca
    62221 atattgatat aagggtcaaa cttttgaatg gttactttga gaccacgatt tttcaagaga
    62281 cggcctagac tcgctgccac aatccctttc ccaatagacg ataccacacc accagttaca
    62341 aaaatatatt tcgtagacat agattcctct ttctaaaatg ctcaaggtct tgttaactac
    62401 gaggggatat agaaaacaag accctactaa taagaataat ctgggacgac tgcaccagat
    62461 tcacaactaa tactcttcga aaatctcttc aaaccgcgtc aacgtcgcct tgccgtagat
    62521 atgtgttcct gactttgtca gtcttatcta caacctcaaa acagtgtttt gagcagccta
    62581 cggctagttt cctagcttgc tctttgattt tcattgagta taaaatacaa gaagataact
    62641 tcttgaaaaa acaaaaatag ctccctaaga actagggagc cccgacctct aaaagaggtg
    62701 cccaaacaat atgataccta aaaataggat aattgtcaat agctaactct tattcctcgc
    62761 tggtttcagc gtcgtcatct gaaaactcgt cgtcgtcttc gttgagatcc acatcttctc
    62821 ccaagtcatc tggagcgatt tcgttgattt ctgcatcata agcttccact tcattttttt
    62881 catcatctgg attttcatca tcgtatgaaa gagctggatc tgcttcgtat gcatcttcgt
    62941 cttctggatc atctgcattg tagtcaatgg catctgaatc accatccata aaggcattga
    63001 cacgtttttt cttagctttt ggtgctactt catcgtcgtc attttcttca agagcgatga
    63061 tttcttcgtc gatttcgtcc acaccatacc atgaacgaag accccatttg ttgtccccaa
    63121 gtgagatgaa gctaccgtca aagttcaact ctgtgtagaa caaaggcaaa gcttcgcgga
    63181 tatcgctgtt tgatgttcca aggtagtttt gaatttcgtt tacaagatcg ctaaaatgca
    63241 tctcatgatc gcgaccacga agttccaaga tagcacgcgc tacctcaatc atagatagtt
    63301 cacttttttc ttgcccagca aatacttcta attccaaagc gtttctcctc atttatacta
    63361 ctatcgccag agcgaacaga ctctgacctc attttatcat ttactcttta ttttacgata
    63421 attttgcgga atagtcaaag gttaaggggg agaaagtggc aggattagac taattccaat
    63481 ataaaactcc ttcctttttc tgttgctcca ttttccacaa atccaagcga cttgaaacac
    63541 ctcctagaag catgattgta ggtgtagatt tccttgactc tcaattcttt ccatcctttt
    63601 actcgagcca attcaatcaa agcacttaga atcttttttc caagtcctcg atgttggtaa
    63661 gcggaattcc caatcacaat ggggagatta tcctgagata gtgtaatatc cccaattgga
    63721 aaccattctc ccttctcctt gacttcaatc caaaaaagct caccatgccg atccaaatag
    63781 gaatacatgg cttccaaggt cgcttgactg taaggaagct tcaccccatc tacgaggtaa
    63841 accaagttca catcctgata ccaagcaaaa gcttcctcac aataattgac cttataataa
    63901 ggaacaaaac acaatgcact accttttcaa caaaagagtt gctgcttgat taaaaccatc
    63961 acaccagtta taccattttg cttcataccc atcttgagct aggatacgat cttctaaatc
    64021 aaaaacagag taaatctttc tttcctcgca agcttgcgca tagagatgat atagttcatc
    64081 accaccatct ctatcccact cagcagaaat cgtatcccga cctgccaata aagcctgata
    64141 agccctgtga tgcccatctg taatcagcaa acaatctcca aaggcaagaa tactgattgg
    64201 atcgacttgg tttgtttctg ccgactggta aagcatctga atatcttgca acttcttttc
    64261 tgataaatat agttgagtcg gatgaagatc tactatattg actttcattt ctttctcctc
    64321 aagggaattc gatactcact tctgtttgcc tttaaatcgc cattggaagc ggagcttgtc
    64381 atagaaggga aactcgataa acaagactcc caaacccaca cagaaactgg caagaacatc
    64441 tgatgggtag tgaactccca gatagactct tgataccagc acactgacta ggtagaggcc
    64501 aaggacgatt tgtacgattt ttctccagac ctgatcttta atccgctgac taagaataac
    64561 aatcaaagtc cctaccatca gcgttacagc tagagaatgc ccacttggga aggaaaatcc
    64621 cttctcctcc accagatgta agatagctgg tcgtgggcgc tggtagatat ttttaaaggt
    64681 cacgattaaa agacctgcca aagccagatt tcccagcatg aagaaacttt ctatcttcca
    64741 tcgcttacga taaaagacaa aagctataat gacaacccaa gtgataatca ctggaatatc
    64801 aatcagatgt gtgagggatc gaaaaagaat agtcaaataa tctggtaagt ctcctcgaat
    64861 ggcagtctga atcgattggt caaaaccgac cagcgtttca gggtaaaatt tgaccatgta
    64921 gccaagaata acgaaaagta aaagggcaaa actgcccttc attaaaaatg tttgtttatc
    64981 tttcatagtg ttttaaggtt ggtttcaaaa ggacgtacaa caaccagaat gaaacggaaa
    65041 agattacacc ctcaatcaag ttaaaaggta ataccatggt cattaggtag ttggaaagtc
    65101 ccaaaatttt tccaatatca aagttagcaa acttagcgta caaaggaaca gcataaacat
    65161 agttgagaac caacatggcc aaggttaaac caacagttcc agctagagag cctagtagga
    65221 aacgaagggt tgtccgttcc tttttccaaa tcaaagcaaa tacgatgaca aaaactccca
    65281 aagctacgat attcatcggc aaaccaatgt aagtattcac tccttggctg ttaagaagca
    65341 atttcaatag tgagcgaagc aagagcactc ctagagcagc aggcaaatcc atgaccacca
    65401 gacccacaag gactggcaag atactaaatt cgatcttgag gaaagatgcc gctggtaaaa
    65461 gcggaaagtc aaagtacatc agcacaaatg agatggctga tagaattgca atggtcgaaa
    65521 gtcgacgtgt gtttgtcata acaggttcct ccaattttct ataaaatcag aagaagttgg
    65581 aaaggattcc tctatctatt ctcacttttt atatcccaaa agttccctct tactctatta
    65641 aagaaaaaca aagcaagtgg ttacaatccg gctataaatc tatcaaaaca gacaaagcta
    65701 ttctttcgtc ttctcccatc cagactatac tgtcggttgt ggaatctcac cacatcagct
    65761 tgcgctcgcg gacttatttt gctaagatat tttagattta tctaggcgtc gcagtcgaag
    65821 ataatactta aggtatatcg agacaaaaca acgacgagaa agctaaaata gctagtcaaa
    65881 tttaccgccg gtcgggaatt tcaccctgcc ctgaagactc ttttatcata acaaaaaacg
    65941 cttgcaagcg caagcatttt gttcattttc attttttatt tcaatttatc cacttcatag
    66001 gtatggacga gctcaagacc tgcaaagttc tgctggcgaa gagcctcata gacaatcatg
    66061 cagacggtat tagacacatt gagactgcgg acatgttcat cattcatggg aatacgaaga
    66121 gccttctcag gatgttctcg cataaaatct tcaggtaagc ccttgtcttc acgtccaaag
    66181 agaaaataat ggtcctcgtc agtcgataaa tccacctcag aatagacttt ttccgcgaat
    66241 ttcgaaatca gatagagttt tcccttcatc cgagacatga aatcttccaa actctcgtaa
    66301 aaataaatct ctagcttatc ccagtaatcc aatccagccc gcttcatctt gcggtcatca
    66361 ataggaaagc ccataggctt gatgatgtgg aggggagaat tggtcgcagc gcaagtacgc
    66421 gcgatattgc ccgtattttg tggaatttga ggttcaaata atacaatgtg atttgtcatg
    66481 acttgcttcc tttcaccatt gcaaaaaaat agccacactg cccggagtca agctcagcaa
    66541 acagcgtggt taaggcatcg ttaacttacc tcacaacagg tttgaagtaa atcagcgaaa
    66601 ctactttctt agtataacac tttcagaatc attgtcaata gaaacgactt gattttttaa
    66661 attttttcaa gctatttcca agggttgtaa aatcgtccct gattctgcaa gataagtagt
    66721 aaactagcta ctaaaaacaa ggttgccaag agcaaggtaa tatagtctcc ttttttcaag
    66781 gcctgataac tataccatgt gcgttttttc tctttcccaa agcggcgaag ctccatggca
    66841 gtcgcaatgg tatcaatgcg ttctagcgag ctaaaaatca agggcgtaat aatgagcaga
    66901 ttgcctttga ttcgttgcat aagagaagct ttcttggata attccatccc acgcgcctcc
    66961 tgagacatct tgatagtaaa gaattcttcc tgcaaatctg gaatatagcg caaggtcagg
    67021 ctgacagaat aagcaatctt atagggcaca ccaatttgat ttaaactgga agcaaactga
    67081 ctaggatggg ttgtcatcaa aaagataata gccagaggaa tggtgcaaag atacttaatg
    67141 gccaaattta gcagataaaa gagctcctgg ctggttagag tgtagacacc gattccctgc
    67201 caaatcacac ttctctctcc ataaagtcca accccatact cgggagaaaa gagatagacc
    67261 atcaaaacgt ttaaaacggc aaataccgtc gcaaaaacgg ctacaaagga gacatcttta
    67321 aagcggattt ctgataaata gaggagaaag actgaaaaga tggcaatcag caagagcatt
    67381 ctggtatcat agctaatcat ggccgccaat gataccagaa tgaaaaagag aagtttccca
    67441 gctcctgaca agcgatgaat cacagtatct ctatgctggt aaccgattaa tttagcttgc
    67501 atccctctct cctttctttg taaaatgccg ttaaatccag tggatccaca tctagtttct
    67561 tagccaagtt aaagatggag gtttctttta gattggcttt tactaacagc tcaggatcgc
    67621 tcaacagact ggctggaaca gtatcggcaa tcaattctcc atccaccatg acaaggaccc
    67681 ggtctgaata atccagcatc aattgcatat catgggtaat catgacaatg gtatgccctt
    67741 tttgatgtaa ctcttcgaga aattccataa tctcagtata gttcttctga tcttgacctg
    67801 cagtcggttc atctaggaga ataatttcag ctcctaagac caaaattgaa gcaatggtga
    67861 cacgtttttt ctgaccaaat gacagggcag aaataggcca attacggaat tcataaagtc
    67921 cacagatttt caaggtttca tagactctcg tttcaatttc cttctcatcc acacctcgca
    67981 aacggagccc tagagccacc tcatcaaaaa tcatattggt tgaaatcatt tgattaggat
    68041 tttgtagcac atatcctact cgttccgccc gctctgcaac agaatcgcct tttatatcct
    68101 gtttttccca aagatagcgt ccttccgtct gaataaagct acttatagcc ttggctagag
    68161 ttgatttccc tgctccattt tttccgacaa tagcaatctt ttcacccttt ttaatatcta
    68221 aatgtaggga ttttaaaatc ggtctatcat cataagaaaa agatacttcc tctagtctaa
    68281 agagtgactg caattctgag gtttctttta ccagttccgt ctgtaactgg acttgccctt
    68341 ttgagataga caagttatcc agatctgcta attgttcttc cttgactaag tccacaccta
    68401 attgacggag agtggttaga taaaggggtt ctcgaattcc attttgagtc aataaatcag
    68461 tcgcaagcaa ctggtcaggg ctcccattaa aaaggatacg accatcgttt atcaagacaa
    68521 tccgatccac agggcgatgc agaacgtcct ccaaacggtg ctcgataatc agagtcgtcg
    68581 tcccctcttc cttatgaatc tggtcaatca attcgataat atcctgacct gacttgggat
    68641 ctagattggc gagtggctca tcaaacaaga gaatcggact ttcatcaatc aagacaccag
    68701 ccagactgac tcgctgcttt tgtccacctg acaaatcctg aggacgctga tccagtaaag
    68761 aaagaaggtc caacttttca gcccatttat aaacacgacc tttcatctca tctagggctg
    68821 tcacatcatt ttccagagca aacgccaaat cttctgccac agacaagcca ataaactgcc
    68881 catctgtatc ctgcaaaact gtgctaacca gatgagactt atcatagatg ctcatatcaa
    68941 aggctacttg accctttatc aaaaattctc catatgtctg acccttgtaa atattgggaa
    69001 taatcccatt caaacactga cccaaggtag atttacctga cccagatggt ccaacaatta
    69061 agactttctc tcccttgtaa atggtcaagt ctatcccttg caaggtcggt tcttgttgtg
    69121 tttcataccg gaaagagaaa tccttccact caattatagc ttctttcatc ttactctctt
    69181 cattcgcttc ttagacttct attttatcat aaatcaagcc cttcttgcag tctctcctct
    69241 taaaatctta gcgccaaaaa gattcctatc ctagcttact tgcctaacta atctataaac
    69301 atcgaaaaag actagttgcc cagccttccc catcatttta tactcttcga aaatctcttc
    69361 aaaccacgtc agcttcgcct tgccgtaggt atggttactg acttcgtcag tttcatctac
    69421 aacctcaaaa ccatgttttg agctgacttc gtcagttcta tccacaattt caaaacactg
    69481 ttttgagcaa cctgcgactt gcttcctagt tttctctttg attttcattg agtattagtc
    69541 ctttttcaaa cttcctgcac gagtttgggt tcctgcatag gcaagtaaga gaagagttcc
    69601 tgcaatagct acagatacac cattggcaat tcccgcaaca atcccttgtg caaatacttt
    69661 ttctgccgct tcttgataaa tcacaacatc tccaagtggt gccaagacac cccaaacaag
    69721 ggcatttgca agtagttgaa tgagattaaa aataagaata tctttccagt caaaaacact
    69781 attgatcacg cgaacgtact ttctaaaaag tcccacaact aaaccaaaga gtccgctagc
    69841 gataatccaa gtccaccata gaccataacc aacaagagag tccttgattg catgaccaat
    69901 caacccgaca agcaaaccga taatcggtcc aaaaataata gaaagtagcg cttgtaccgc
    69961 atactgaagc tggatgcttg tatttggaac aggggttgga atgttgatca tcccgatgac
    70021 gacaaagagg gcagcgccaa ttccgacagc aacaacttgt ttaattgtaa atttgatttc
    70081 catactattc tcctatttta tccttctatt ttctttattt caatggtcca agatgaaccg
    70141 acacctacat tataggcctt ggcaaaggaa ccttggttga tagccaaacc taaacgatag
    70201 agagagttga tgtaaaggat gggttgccca attctcacat ctgcaaatga tttgccatag
    70261 acaagctgat tttgatagac cagcatatca gcatgataga tggtcacttc aaaacgatca
    70321 ccaaattctg gttccagctt gtaaaattct tcccgtgtga tagaggtcca aagcgaaccg
    70381 aaacgcacat ccagaatatc aatggctccc ttcaccagat gatcttctat gatggtcgct
    70441 acgactggaa gctctacaat ctgttccaca ctgagctctg gccctacttc ctcaaaagta
    70501 atgtgaccac tggccagttt agcaccagta taggcataga catcacgacc gtggaaggta
    70561 taagaatgct ctgtgttttg acgcctattg gccacctcag aaatctcacg aatggctaca
    70621 atgccaacgt gtttcttgat aaaggaaagc gtcccattat ctggcgtgac aatgtattga
    70681 ttttttgcag tcttggcaac tacactctta cgtttcgaac cgacacctgg atcgacaacc
    70741 gatacaaacg tcgttccctc aggccagtaa tccaccgtct gaaagagacg atagctcccc
    70801 tcaaaaatat tataaggcgt gatatcgtgc gtcaagtgat ggatttttaa ggttggagac
    70861 tcttctaaag ccactccaat catagccgat accgcaccat caaccagacc aaagtctgat
    70921 tgtaatacca gtaaattatt attcatttta tctccttgta tatcctttat cataccatat
    70981 ttcagagaaa gtcgctaata gctatttcaa ttggttaggg tatagtttta ccttatagca
    71041 aatttcctac taaaagttct tgttattagc tagtaggtgc attttttctt gaaaaagggt
    71101 atgatagtta catcatgaaa aagtaggttt tattatgaaa attatccttg tcggaggggg
    71161 aaaagttggt tttgctctct gtcgctcctt ggttgcagaa aagcatgatg ttttgctgat
    71221 tgagcaagac gaagctgttc tcaatcatat tgtcagtcgc tttgatatca ttggtatcct
    71281 tggtaacggg ggcgattttg ccattcttga gcaagccagc gtccaagatt gtgatatctt
    71341 tatcgccctg actgagcacg atgaagtcaa catgattgca gcagttctag ccaagaaaat
    71401 gggagctaaa gaaactatcg ttcgggtgcg gaaccctgaa tattctaact cttatttcaa
    71461 ggaaaagaat attctcggtt tttctcttat cgttaatcct gagctcttgg ctgcccgcgc
    71521 tatcgcgaat atcattgact tccccaacgc cctgtctgtc gaacgctttg ctggtggacg
    71581 cgttagcctc atggaatttg tcgtcaagtc caccagcggt ctttgccaaa tgcccatttc
    71641 tgattttcgt aaaaaatttg gtaatgtcat tgtctgtgcg atagagaggg atcatcaaat
    71701 tatcattcca agcggtgaca tgactgtaca ggataaagat agaatctttg tcactggtaa
    71761 ccgtgtcgat atgatactct tccataatta ttttaaatca cgcgccgtga agagccttct
    71821 catcgttggg gcaggtagaa ttgcctatta tctacttggt attctcaaag atagtcgtat
    71881 cgatacaaaa gtcattgaaa tcaatcctga aatcgccagc ttctttagcg agaaattccc
    71941 aaatctctac atcgttcaag gagatggaac cgcaaaagat atcctgctgg aagaaagtgc
    72001 tcaacactat gatgccgttg cgactctaac aggagtcgat gaggaaaatc tgattacatc
    72061 tatgttcctt gacagggtag gtgtacagaa aaatattact aaggtcaatc gtaccagtct
    72121 cctcgagatt atcaatgcgc ctgatttttc aagtatcatc acacctaaaa gcatcgctgt
    72181 agatacgatt atgcacttta ttcgtggtcg agttaatgcc cagtattcag accttcaagc
    72241 catgcaccat ctagccaatg gccaaattga aaccctgcaa ttccatatca aggaagccaa
    72301 taaaatgact gccaaacctc tttctcaact gaaattgaaa aaaggggttc ttattgcagc
    72361 cattattcga aagggcaaga ctattttccc aactggggag gatatgttgg aagttggaga
    72421 caagctccta gtaacaacct tgttgccaaa catcaccaag atttatgact tgattgcgag
    72481 gtaagaaatg aataaaagta tgattcgtta cctcctttca aagttacttt tgattgaagc
    72541 tgttctcctc ttggttcctg tggctatcgc tgtctattac cgtgaatcga gccaagtctt
    72601 tacagccctc ttttcgacca tagggattct cgtattgtta ggcggttcag ggagtttaca
    72661 gaagccaaaa aatcaacgga tttatgccaa ggagggagtc ttgatcgttg ccctctgttg
    72721 gatcctttgg tctttctttg gtggtctccc ctttgtcttt tctgggcaaa tccctagcgt
    72781 tattgatgcc ttttttgaaa ttagttctgg gtttacaact actggagcaa gtattttgaa
    72841 cgacatttcg gttctcagcc gttccctcct cttctggcga agttttaccc acttgattgg
    72901 agggatggga gtgcttgttt ttgcacttgc tattatggac aatgccaaaa atagtcacct
    72961 agaagtaatg aaggctgagg ttcctggtcc tgtctttggt aaggttgtat ccaaattaaa
    73021 aaacactgcc cagatcctct atctccttta catagccctc ttttccctct ttgtcatcat
    73081 ctattatcta gccggtatgc ctctctacga tagttttgtc attgctatgg ggacagcggg
    73141 aactggagga tttaccgtct ataacgatgg aattgcccac tatggtagct cactgattac
    73201 ctatctggtt agtataggag ttttggtttt tggggtaaat ttcaatctct actactacct
    73261 tatgctccgt cgggttaagg ccttctttgg agatgaagag cttcgggctt acttggtcat
    73321 cgtgctggtt tctacaggct tgattaccct caatactctc tacctctacc caggattttc
    73381 caaaagcttt gaaatggcct tcttccaggt ttccaacatc attacaacaa ctggttttgg
    73441 atatggagat attaccaact ggcccctctt ctcccagttt atcctcctct tcctcatgac
    73501 aatcggtggt tctgctggat caactgcagg tggactcaag attattcgag gcctcatcct
    73561 ttcaaaaatt gccaaaaatc aaattttgtc cattctatct ccccaccgtg ttttgactct
    73621 ccatgtgaat aaaacggtga ttgataagga tacccagcat aaaattctca agtactttgt
    73681 catctatgct atgattttgc tatcccttat ctttattgtc agcctagata gcaatgattt
    73741 tctgatcgtg accagcgctg tctttagctg tttcaataat atcgggccta ttctaggaac
    73801 cacttctagt ttctcaatct ttagtcctat ctcaaaaatt ctcctctcct ttgcaatgat
    73861 tgcaggccgc ttggagattt acccaatcct acttctcttt atgaagagaa cttggtctaa
    73921 gagataaaat acaaaatctc tctttttaca attatgaaag agggattctt atattatact
    73981 tcctgcggaa caaaatatgg tatagtagtt ctatgaatta tgaagcaagt aaacaactaa
    74041 ctgatgcacg attcaagcgt cttgttggtg ttcagcgcat gacttttaaa gagatgttag
    74101 ctgtattaaa acagcttatc aacttaaaca cgcaaaaggt ggacgaaaac ctaaattaag
    74161 cctagaagac cttcttatgg tcactcttca atatgtgcga gagtatcgaa cttatgaaga
    74221 aattgcggct gattttggta tccacgaaag caacttaatc cgtcggagcc aatgggttga
    74281 agtaactctt gttcaaagtg gtgttacgat ttcaagaact cctctcagtt ctgaggacac
    74341 ggtaatgatt gatgcgacgg aagtacaaat caatcgccct aaaaaaagaa ttagcgaatg
    74401 attctggtaa aaagaaattt cacgctatga aggctcaagc gattgtcaca agtcaaggga
    74461 gaattgtttc tttggatatc actgtgaact attgtcatga tatgaagttg ttcaaaatga
    74521 gtcgcagaaa tatcggacaa gctggtaaaa tcttggctga cagtgattat caagggctca
    74581 tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag ccgctaacag
    74641 ctgaagataa agcctataac catgcgctat ctaaggagag aagcaaggtt gagaacatct
    74701 ttgccaaagt aaaaacgttt aaaatgtttt caataaccta tcgaaatcat cgtaaacgct
    74761 tcggattacg gatgaatttg attgctgata ttatcaatca tgaactagga ttctggtttt
    74821 gcaggaagtc taatatgaaa acaagacgac ttccatatag gaaaccgcct tctagctatg
    74881 ttgagtgatt tatattaaaa taacttttct tctagcttca ttttattatt ataaaaacat
    74941 tcatcataac ccccagaact taaataacga tttttattca agatacatac tcctagaata
    75001 aactttatat gaaatcccca tttttgtttt tacaattctc ctgatactca atgaaaatca
    75061 aagagcaaac taggaagcta gctgcaggct gctcaaaaca ctgttttgag gttgtagata
    75121 gaactgacga agtcagtaac atctatacgg taaggtgaag ctgacgtggt ttgaatttaa
    75181 ttttcgaaga gtattagtta aatcttgctt aatatatcta caccatacta ttttacatat
    75241 agtatttagc acgacataat actgaagtct ctctccaaaa aacggttatg cctctttgaa
    75301 taggaagttc tcacaagaaa agcatctcca cgtttcaact tcatatggct caaaaacaat
    75361 caattgatgc taaaacctgt acctagatgt ttcggttcat aaaaccatga aactgtaaaa
    75421 atggatgaaa ttgatagcgg gtagtcagat caagagacat cataactcta aaaagtcaca
    75481 atatagtaga ttgaagttga aatagtacac tttggtttct aaaacattat tataagttag
    75541 tttaaattcc ttaatcaatt tgtacatttt tatttcattt cactatagat aagttcatcc
    75601 tcagaaaaat atcattctaa ttgttgaaat ggatatataa acaggggtat taacattaaa
    75661 tgctcatgaa acaacgaata caggtatcaa aactgtaaca aaacaagtcc ctaaatttac
    75721 taaagacact gctcaacttt acacctgtaa atggttgttg tataataaag ttacaaagat
    75781 gtacgaccac accgttgtaa atcatagtgt tcgcgaatat attactgata gcatttctac
    75841 aaatacaatt gaagaggcta gatagggttt aaacgaaata tgtcagtgtt ttagcactcc
    75901 tagccttcat atcatttaaa gaattgtata gacaaaattt ttcccaatac agacactcgt
    75961 aacaactgct tcatttttct accaacatat ttaggaacag gataagatac aagagaatta
    76021 atccatagat cagttctata ccaatctaag ataaataagc taaaaaacaa ttaataataa
    76081 gcaaatagat tccaaatttt ctctatctgc tcattttaat aaacaatact agtgtaacta
    76141 tccttccagt cagaagcttg tcaaaccaca tcgaaaattt ttctaaaatt tatctcgtta
    76201 ggcaatcaag caaaaactcg acgatagtac aaacattatc atacaggatt gacttcctaa
    76261 attatatgct ttagtaaggt tttcggataa gaaaaaaggt tcattttaca tctctaaaca
    76321 ctcttttcta agatgaaaaa cagaattttt cgattgtgat ttaaagcaac aagaagattt
    76381 tcagtatcat cctatagata cgagctaatt aagaaaaact acatttttga atataaacta
    76441 caataagata aactaaattt cataggagga agacaatgga ttggtacgat tatatgatac
    76501 aggcatccaa acaatcacaa ttcaacgcaa gccattggtt tcgctatttg cgaaaagtta
    76561 tttttgaaga ctattcttat ttaacaaacc aagatgtaaa aaagttgcta gactccaaag
    76621 aactaacccg ttttcaaaaa attagcttga agtatgcctt tcaagagcat actccaactc
    76681 ataaatatgt gatttcatta aataaacctg ctaagttaac caatgttcaa aaattgatgg
    76741 agaaatacaa acatggataa aatgaaaccg gtcttccaag ccctaaataa ggaattaatt
    76801 caggaaaatc tgactttaac aattatctgt gtcggtggtt atgtcttaga atatcatggt
    76861 ttacctgcca cacaagatgt tgatgctttt tatgaccaaa atcagaaaat aaatgaaatt
    76921 attgctcgtg taggaaaaca gtttaatctt aacacccacg aagagttatg gctcaacaat
    76981 catgttgcaa agcaaatatg aacaaacaac ctcccttaag tttatgcgaa tccttgtagt
    77041 catttgagaa tctgaccgtt ttagtagtcc ctattgagta tgtgttagga atgaagatga
    77101 tgagtatcag agagcaggat ttgcaagata ttggtgcaat tattaaatac aaaaactttc
    77161 attcaccatt cgatgccttt aaatatttaa aagacatggg atttgatact attgacctct
    77221 ctgttctatt agaaggtttt agttatgctt atggtatgga ttggttagaa aaatttttta
    77281 aagaaaatca agataaactt cgcgaatttt attaacagta tcaaacaaga tgattgtcaa
    77341 ttagacagtc gtcttgtttt tatgatgaaa tgaaataaga ataggacaaa tcgatcagga
    77401 cagtcaaatc gatttctaag aatgttttag aagtaaaggt gtactattct agtttcaatc
    77461 tattatattt cagattcggt ccactattcc ttcccaaaaa cattgcatat tgcgccgaag
    77521 gaattgctca cactatccca agcacaaacc cctcagtcga ttgaccgagg gttccttttt
    77581 attattcaag aacttgatta gctcaatgca tccaaggcat catccattga aagaacttcg
    77641 tggaagacac gttgtgtcaa ttcagttttt tgttctggag tgaggtattt agtgtttaca
    77701 cagtatccag agatacgtac gataacgtct tcgcctgaca tgatcttttc gtaaacatcg
    77761 ttcaagtcca taacgttcaa gttaacgtgt tgtccaccgt tttcaaagta accatcaagg
    77821 attgttacca agttatcaac ttgttcatca cgagtcttac caagagcgcg aggtgatact
    77881 tgtgtagtca atgagatacc gtcagctgca taactaaagt caaggctaga aagtgagttc
    77941 aagttttgca accaaccacc tttagctttg ttagatgggt tagcacctgg tgagaagaat
    78001 tcaagtttag acaagttcac agaaccatct tcgttgaggt atacaccttt gtgaactggt
    78061 gagttaccag tttgtttaga gtaagcaacg ttagatgtga ttgtcaaaag tgatactgta
    78121 gcttctgcgt ctttgtatag tttgtggcta cgtagacgag ttgtgtaagc ttcgatcaac
    78181 cattctgcca attcgtttga acgtgggtca tcttcacccc agcgtgggta gtcaccgatt
    78241 gtttcgtaat cgtagatgta gccatcttca tcacggattg gtttaactgt agcgtattta
    78301 atcgctgaca atgtatcaac agtgttagca aatccacaaa taccgaatcc catgttggca
    78361 cgttgtttag ttggcaagaa ggccatttga acagcttcgt agttatactt atcagtcatg
    78421 tagtggatga tgttcaaggc atctacgtaa gtgtcagtca accagtcaag agatttttca
    78481 aagttcgctt taactgattc aaattcaaga acttcgtcac gaataggatc gatgtcaaat
    78541 actttgtagt ctttgtgaac atcgtcgtaa ccaccattca aaccagtaag aagggctttg
    78601 agaacgttta cacgagcacc gaagtactgg atgttgtggc gttgttcttc attttctgga
    78661 tcaagtggag acacacagca tgagatacag ctcatttcac catatccgtc tttagccatt
    78721 gttgttacac cttcgtattg gatagaagag tgtttgtggc tcatgtgcat acagtagcga
    78781 cggaagttgt atggcaattt gtcagtccaa agaactgtca agtttggctc tggagagtta
    78841 ccgatgttgt caagagtgtt caagaaacgg tagtccatct tagtaacacg gtgacgaccg
    78901 tcgttaccca taccagccat agaagttgtg atgaatgttg ggtcacctga gtacaattgg
    78961 tcataagctt ttgtacgagc aaatttaact gtacgaagtt tcataacgaa atcatcaacg
    79021 aattcttgga tttctgattc agtaaatgta ccacgagcaa ggtcacgttc tgcaaagatg
    79081 tccaatacga ttggtacacg acctagagat gtagcagcac cgttaatcac acggcagaca
    79141 gccatgaaag caatgttaac ccattggatt gcttctttca cgttcatcgc tggtttgcga
    79201 acatcaaccc cgtaaaggtc acccaggcga acaacttgtt gcaatgcttg gtattgaagg
    79261 tttacttctt cacgaagacg gattgtttct tcatcgattt ctttgattgc attccagtca
    79321 tttacttttt cttgcatcaa gtagtctgca ccgtaaagag caagacgtgc gtaaacaccg
    79381 atgatacgtc cgcgtgagta tgcatctgga agaccagtta cagtgtgtgc gtgacgagcg
    79441 cgacgaatat ttgaagtgta ggcacggaaa ataccgtcgt taactgttgt tacatattta
    79501 gtgaagattt cgtgaacagc tgggtctggt tcgtatccat tttcttttaa agtagtttca
    79561 gccatacgga taccaccttt tggcatgaag ttcaatttga agagttcatc gttttggata
    79621 ccgaagataa cttcattttc tttgtcgata aatccagcag ggatatcagc gatagatgtt
    79681 ggacgagtgt ccattgggaa acgagtttct tcgtagtgtg ctttagtttc ttctacaatt
    79741 ttcttgatgt gaagtgaacg ctctgttgat cctgcaagga agctttcgtc tccatcataa
    79801 ggtgtgtagt tagcttgtac aaagcgtgat acacttgctt tttctttcca atctacgcct
    79861 ttgaagcctt cccaagcttt gtcaaaaata tcttgtgctt caacaactgt cttaacaacc
    79921 atattaatgt cctctttttt ctagtaacag tcatctgtta cattcatgag acaagtatac
    79981 catatagtaa ccgttttcaa caagtgaaaa atccctattt ttacactttc ttttctaaaa
    80041 cagtctatat tttatttcaa actgtattat atttttgaaa aaataaagtc cttttttctt
    80101 tttttcagaa aaaagggtat aataaaagaa aataagcagt aacactcaat ggaaatcgaa
    80161 aagcaaacta ggaagctagc cgcagattgc tcaaaacact gttttgaggt tgcagataga
    80221 gctgacgtgg tttgaagaga ttttcgaaga gtataaaaag gtgctaggca tgttgatttt
    80281 tcctttgtta aatgatttgt caagaaaaat catccatatt gacatggatg ccttttttgc
    80341 tgcagtggaa atcagggata atcctaaact cagaggaaaa cctgtcatta ttggaagcga
    80401 ccctcggcaa acaggtggac ggggagtcgt ttctacctgt agttatgagg caagagcttt
    80461 tggtgtccat tctgccatga gttccaagga agcttatgaa cgttgtcccc aggctgtctt
    80521 tatctcaggg aattatgaga aatacaagtc tgtgggactc cagattcgag ctatttttaa
    80581 gcgctataca gatttgattg aactcatgag cattgacgaa gcctatttgg atgtgacaga
    80641 aaataaactc ggtatcaagt cagcggtcaa aattgctcgc ctcattcaaa aagatatctg
    80701 gcaagaactc catctaactg cttccgcagg cgtttcttac aacaaattct tagctaaaat
    80761 ggcgagtgat tatcaaaagc cacatggttt gacagtgatt ctacctgaac aggctgagga
    80821 ttttctcaaa caaatggata tttccaaatt tcatggagta ggaaaaaaga cagtagaacg
    80881 tcttcatcaa atgggcgttt ttactggtgc tgatttactt gaagttcctg aggtaaccct
    80941 aatagaccgt tttggtagac taggctatga tctgtatcga aaggctcgtg gcattcacaa
    81001 ctctccagtc aaatccaatc gcatccgtaa atcaatcggc aaggagaaaa cctacgggaa
    81061 gattctccgt gccgaggaag atatcaaaaa agagctgact cttctatcag aaaaagtcgt
    81121 tctcaatcta catcaacaag aaaaagctgg aaaaattgtc attttgaaaa tccgctacga
    81181 ggacttttca actcttacca aacgaaaaag tcttgctcaa aaaacacaag atgctagtca
    81241 gataagccaa atagccctgc aactctatga agaattaagt gagaaagaaa gaggtgtccg
    81301 cctattgggg attaccatga ctggatttta aagctcaatg aaaatcaaag agcaaactag
    81361 gaagctagcc gcaggctgct caaaacactg ttttgaggtt gcagataaag ctgacgcggt
    81421 ttgaagagat tttctaagag tataaaacct tgaagagttg ccccttcaag gtttttctta
    81481 tacaaataaa cggacaaaac tgtaaagtag caaaacacta ccaagcacga tacggtattt
    81541 accaaaaagg gtgaagtcgt gttttttcac atagctggtc aagaagcgaa tagccaccat
    81601 gctgaccgca aaagctactc ccatcgcgac caagagcaaa aacaattgcc caaagctcaa
    81661 gagttctccg gctttcacaa atttgaaaat ctttaaggca ctagctccaa acataacagg
    81721 aatcccaaga tagaaggtaa attctgtcac aactgaacga ctggttccat ttaacaaacc
    81781 accgacaatc gttgcacctg aacggctagt ccctggtaaa agagcaagaa cttggaagag
    81841 tccgatatag aaagcggtcg tataaggaag cttgtccaac tctgttacac ttggctcgat
    81901 agcacgcgct ttattgcgct tttccaaata gatgaaggca accccgtaga taatcaacat
    81961 gagagcaact gaaaccatgt tatggaagtg ggtatcaaac caatcatcaa atttaaagac
    82021 accaagtaaa ggtaaagtag caatcaagac cttcaaccat agtctccaag tcttacgaac
    82081 ttcctgtttg tccttagtcg gtttaaaagg attgagcttg ttaaaataaa tcaccataac
    82141 tgctaagata gcaccaagct gaatcacgac attaaacatg gacataaagg cttcattttg
    82201 attttggtat tggataaact cctctgctaa aatcaagtga cctgtactgg aaatcggcaa
    82261 ccattccgta attccttcaa caatcccgaa gaagatagat tttaaaattt caataagata
    82321 catagattac tccctatatt atatttagcg cagttagcta ctgccaaagc ccaagtggta
    82381 tacttggaat aagccactgt ggattagttc atttcctcca atcgcttgac gatttccgaa
    82441 aggctctaac cacagctttt gtttcaattg gtaatgagtt tgataacgca tagacgtttt
    82501 atctcgtcta aggtaacaag gcaaaaagtt cgtggataac caagtagact tgaaatacta
    82561 tatctggagg tactcccatg ctttatgtgg gcattgatgt cgctaaaaat aaacacgatg
    82621 ttacagcctt gaatgttcca ggaaaaactg ttcttaaacc actcactttt tcaaataata
    82681 aagctggttt tgaactctta gatctgtctc ttcgacagct caaccaagac tgtctcatcg
    82741 ctcttgaaga tactggacat tatgccttta atctactgaa cttcctgcat gaacaaggat
    82801 atgaagttta cacctacact cctttgctca tcaaggaatt tgccaaatca ttatcacttc
    82861 gcaagactaa aacggataag aaagacgctc atggcatcgc tcttaaactt ctttctgacc
    82921 ccaatcgtga acaatttcaa cacgataatc ggcaagtaga actaaaaata ctggctagac
    82981 atattcatcg tctcaagaaa aaacagtctg attggaaagt acaatacact cgttgtcttg
    83041 atatcatctt tcctgagttg gataaaatcg ttggaaagca ttcagaatat acctaccaac
    83101 tcttgacacg ctaccctaat cctcagaaaa ggattgaggc aggatttgat aagctgatag
    83161 aaattaagcg attgaccgct tctaaaattc aggatatcct ctcagtcgca cctcgttcta
    83221 tcggaacaac atctcctgct cgtgaattcg aaatcatcaa acattacaag aggctcattg
    83281 acaaggtgga aaaatgtgtc aatgacttga tggctgagtt caactcggtc atcacgacgg
    83341 tcactgggat tgataatcgt ttaggggcgg tcattttagc cgagattcga aatattcatg
    83401 cctttgataa tcctgctcaa ttacaagctt tcgctggact ggattcttct atttatcagt
    83461 caggtcagat tgatttagct ggaagaatga tcaaacgggg ttcccctcat ctgcggtagg
    83521 cactcataca agctgccaaa gcatgcgctc gcttttcacc tgcttttaag gcctatctta
    83581 agactaagtt agaataagga aaacattaca atgtagccat catccacctt gcaaaaaaac
    83641 ttatccgaac cctgttttat atcctaaaaa agagctgcca tttgacgaac aaaaagtgat
    83701 gtaatttctg aaattaacac aggattacct ttgaaaaaat ggactttttc aagggctttt
    83761 tgccgtgctc taaaatcatc gccaaatcat caaattgaaa taagaaatag tttagataaa
    83821 actattgact tttcttatag tttgtctttt ttctatcttc cattatatca tactttttca
    83881 gtctatggta gctctcttta aaaggcaccg atactgccgc cacctccgcc tccagagaag
    83941 ccaccaccag aacttccact tccagaagat acagagtagg tgcttgctgt atttgcgaca
    84001 ctagcataat gactcatttg tgctgttgaa tgataaaaca tactgtgcca gccataagct
    84061 acatagaaat tgatatctgg attttccact tgaatctgat gaaccttcat caaatgacta
    84121 accttgtccg catagccaaa taaggtcgca tagaccaaga ggcgattcca gaccacaata
    84181 ctttccagtt cagcctgatc caatcgtgca atctcacgca acatattttc aaaactggtc
    84241 cagagatagt agacctcagc tcccgcttca tttagaacac catcacgatt atctagttga
    84301 agcttccaat aatagagaac agacaaaact aaccctagaa aaccaagtat tggcaagggg
    84361 aggtaaagat agccatgaac gtctaaactg tacaagaaca aaccaaatcc gataaatagg
    84421 ggcaagatag tcaagacacc catacccact tgcaaagcct tttccccacc agttaaagga
    84481 cgatagtaat ctgggagtcc ccagaagaca actcgctttc tcactccttc ttgcatctct
    84541 tttaatactg cttcgaaaga agatttgagc tgaatccctc ttgcttgaat ccgtttttca
    84601 tcagaaactt tggctctacg ataaagacta tcagatacct tgtaatccgc aaacaaattg
    84661 gaaagagttt cttctttttt acctgaaaaa gctagatgta ggcagtcttt ctcaaagctt
    84721 gacaaaccat cttcttttac tagcctcaaa ccaactgcat ctccttctga aataatagaa
    84781 acattcccac ggtccatcac atctagcaag gtagcttgaa taagttggtc aaaagtgaat
    84841 ttgccagccc ccttgactaa gggactcact tcctccaagg aggtcgagta gacagcctct
    84901 gataaaacca taggctctaa ttccattggc ggttcgtaga gacgatgatt tttagcatat
    84961 ttgattgaag gagcggtttt tcttctatag ataaaataga aacagatgct caataacaag
    85021 gagatggaaa ggatcgaagg gaagatccaa gtaagtagtt gtttactttg ctctttttct
    85081 ttaacaatcg aatcctctat cttattaaac tcttctaaac gattcccttt caagccctga
    85141 tccctagcgc tagcaaaatc agttcgaggc cagtaggcat gcaactcagc tccacgctta
    85201 gccggaagat tgtctaaacg aatagtataa tcaaggttac tcttttcaac cgttctctct
    85261 ctaaaaagtt tccctgtatg gaaaaagagt ttctcagccc ccttgtctcc ccttacatga
    85321 aattcaaact tttcaataga ctctgaacta tctgtcagag gttgccaatt taattcagcg
    85381 atatcatcat aaaggaaaag taaatttttt aagttccaga cgagatcaac ttcaactatg
    85441 tcgccctcct gacctggatt atagactctc acagtataac catccgcttc ttctgttact
    85501 tcgctagtca catctgctag ttctgcaccg tttttcgcgg cctgaacctt tggatgaggg
    85561 tcaatgtcaa acccgctagg catcttgcca gcacgtccaa gtcccacgat ttggccctta
    85621 aagtcctcct caaactggta aactatcttc tgtctaaact ctgccgtatt atctgcatga
    85681 atatacaaat ccccttgata agagtttatc ttgaaatcaa tggcaaaaac agagagtgga
    85741 agaaggcaaa acaagcctaa caccagtaag aaaaaagttt ttttcatcaa ctaagccccc
    85801 tttttatctt tcttatcatt atagcatttt ttcgtaagca aaggcttact tatgttgaaa
    85861 aattacgcat ttttcgataa aataggagac agttattttt taatagatta gaaataggag
    85921 aaattatgag aaaaatatac ttatctattt tcacaagtct cttgctgatg ctaggacttg
    85981 tcaatgttgc tcaagccgat gaatatttac gcatcgggat ggaagcagca tatgctccct
    86041 ttaactggac ccaggatgat gatagcaacg gagctgtcaa aatcgatggg accaatcagt
    86101 atgccaacgg atacgatgtt caaatcgcca agaaaatcgc taaggactta ggtaaagaac
    86161 ctttggttgt taaaaccaag tgggaaggtc tagtccctgc ccttacttct ggtaagattg
    86221 acatgattat cgcaggtatg agtccaactg cagaacgcaa acaagaaatt gccttttcga
    86281 gcagttacta cactagcgaa ccagttctac tggtcaaaaa agattctgcc tatgcaagtg
    86341 ctaaatcttt ggatgacttt aacggtgcaa aaatcacttc tcaacaaggg gtctacctct
    86401 acgacttgat tgcacaaatc ccaggtgcta aaaaagaaac agccatggga gacttcgctc
    86461 aaatgcgcca agctcttgag gctggtgtca ttgatgctta tgtttctgaa cgtccagaag
    86521 cactgactgc tgaagctgcg aactctaagt tcaagatgat tcaagtagaa cctggtttca
    86581 aaactgggga agaagataca gctatcgcta tcgggcttcg taaaaatgac aatcgtatta
    86641 gccaaatcaa tgccagcatt gaaaccattt caaaggacga ccaagttgcc ctgatggatc
    86701 gtatgatcaa ggaacaacct gccgaagcta caacaactga agagactagc agtagtttct
    86761 ttagccaagt tgctaaaatt ctttctgaaa actggcaaca actcttgcgt ggtgctggta
    86821 tcactctttt aatctctatc gtcggaacca tcacaggtct cattattgga cttgctattg
    86881 gtgttttccg tactgctcct ctctctgaaa acaaagtcat ttacagccta caaaaactag
    86941 tcggctggat cctcaacgtc tacattgaaa ttttccgtgg tacgccaatg attgttcaat
    87001 cgatggttat ctactatgga actgcccaag ctttcggtat caaccttgac cgtacactag
    87061 ctgctatctt catcgtttca atcaataccg gtgcctacat gactgaaatc gtccgtggtg
    87121 gtatcctggc agttgacaag ggacaatttg aagctgcgac tgctcttggt atgactcata
    87181 accaaaccat gggtaagatt gtcctacctc aggttgtccg caatatccta ccagcaactg
    87241 gtaatgaatt tgtcatcaat atcaaagata catctgtatt gaacgttatc tctgttgtcg
    87301 agctttattt ctcaggaaat accgtggcga cgcaaaccta tcaatacttc cagacattta
    87361 caatcatcgc cgtgatttac tttgtcctca ccttcaccgt aacacgtatc ctacacttta
    87421 tcgagcgcag aatggacatg gatacctata ctacaggtgc taaccaaatg caaacggagg
    87481 atttgaaata atgacacaag taatccttga aattaaacac ctcaaaaaat cctatggaca
    87541 aaacgaagtg ctaaaagaca tttctctcac tgtccacaag ggagaagtta tctctatcat
    87601 cggaagctct ggaagtggga aatcgacctt cctacgctcc attaacctac ttgaaacgcc
    87661 aactgatgga caaatccttt atcatggaca aaacgtcctc gaaaaaggct atgacctcac
    87721 gcaataccgt gaaaagttag ggatggtttt ccaatccttt aacctctttg aaaatctcaa
    87781 cgttcttgaa aacacaatcg tcgctcagac aactgtcctt aaacgcgaac gcacagaagc
    87841 tgaagaaatt gccaaagaaa acctggaaaa ggtcggcatg ggagaacgct actggcaagc
    87901 caaaccaaaa caactctcag gtggtcaaaa acaacgtgtg gccatcgctc gtgccctctc
    87961 catgaatccg gacgctattc tctttgatga accaacatca gctctcgatc cagaaatggt
    88021 tggagaagtc ctcaaaatca tgcaggacct ggctcaggaa ggcttgacca tgattgtcgt
    88081 aacccatgaa atggaatttg cccgtgatgt ctctcaccgt gttatcttta tggataaggg
    88141 cgtgatcgct gaagaaggta aaccagaaga cctcttcacc aatcctaaag aagaccgaac
    88201 aaaagagttc cttcaacgct atctcaaata aaaagaaaag gctgcatcaa ccgtgcagtc
    88261 tttttgctgt cctcaaaatg aaaaggcaga ttctctatct ctactacttg aaggtcaaga
    88321 atccgccgtt atccaaagat taatcttcaa atttttcata atttttttca tagaaatcaa
    88381 ttaggcctag ggctgtttca aatgaaatat tttttacttt tgcacgaccc tgcgccagag
    88441 caatgataga catttcacgc gcattcgttt ctttagagat acggtagcct gtgattttct
    88501 tatcacgaac ccagccaaca actgattcta ctttttcaaa gtttgactta gccatgtttt
    88561 tctcctattt tcttctttat aatatttaat tgtatacgtt tttactactt ttgtcaataa
    88621 aaaaaacata tattcaacga aaataattag ttcagaattt tcttacttcc tttttaaacc
    88681 cgataatata taggttttgc tagcctctac accataaata tttgctaata aaaatactgt
    88741 attattaccc tcttaaggtg cgaaattatt caagttctta aaaaatgctt ctctatttcc
    88801 gtaagatagc ttatttcttc gatttaagaa ctgaagatga tagttctaac ctttagaaat
    88861 ccaagccttc actagctcaa aaactcctat ctttcttcct caataaatca tctgagagat
    88921 aggtattcct tatatccttc aaattcatca ctcctttgga tattgaggtg ctagcctaga
    88981 agcagacacc cgattatcta aaccatcctt aatagagatg acaagacaga taagctcagt
    89041 taattactta tatatctttt taatatggta tatttgtcaa caaaaagaaa tcaaatcata
    89101 ccttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaagt tgctcaaaac
    89161 actgttttga ggttgcagat agagctaacg tggtttgaag agattttcga agagtattaa
    89221 agacagtgtg actatgcttg tcaatagata ggaaatcaaa atgaaggatg gaaatctgag
    89281 ccaaacatca taaatgctat aatgaacaga agtaagaatt gcacgataag cttcctaaaa
    89341 ccataggaat cgctcccttt cttcatcttc attatagcac ctatacatca gttgtgcaaa
    89401 taatatgata tttttttatt agtcctcaga caagcatatt ataaagcgtt tcattaccat
    89461 ttaagttaat ataagctgga tcaaaacctt ccattctacg gatcaaacct gcataatcat
    89521 gcttatctgc caaagcgatc ccaatcaata ctgggcctgt tcccttgcta gctcgtttga
    89581 tatactcaaa acgtgtgata tcgtcatttg gacccagaat atcatttaca aactcacgca
    89641 aagcacctgg acgctgtgga aaattgacca caaagtaatg cttgatgcca tcataaatca
    89701 aggcacgctc ttccatttct ggcatacggt tgatatcatt atttcctcca gaaatgatac
    89761 aacaaatggt tttcccctta atatattcag ccaaaacctc taaagaggcg atactagccg
    89821 ctccagcagg ttctgcgaca atcccttgct tagagtagag gtcaatcaaa gtttcagaaa
    89881 tcagcccctc atcaacacct actaaagttt gaacatgttg acgagttgcc tcataggtca
    89941 actgacctac cttttgcaca gcaatcccat ccgcaaattt atcaatttcc ttgagtttga
    90001 ctggacctcc agcctcaaag gcagctttca tggaacgcgc tccattcgcc tctactccga
    90061 taatctcaat ctctggactt gtttccttga tataggtaga aatcccggca atgagaccgc
    90121 caccaccaac aggaaccaag acagcatcaa aatcaatcga ttcttttcga gcttcttcta
    90181 aaatctcata agcaactgtt ccttgacctg cttgaacatg agcatcatca aaaggatcaa
    90241 taaaggtacg attctcagag actgtaaatt cttgagctgc tttggctgag gcatcaaagg
    90301 tatctccaac tagtttaata gttacaaaat ccccaccaaa aaagcgaact tgaccaattt
    90361 tttgttgtgg cgtagtaatg ggcataaaga tagtagcagg aattttcatc tcattacaag
    90421 tataggcaac tccctgcgca tgatttcccg cagaggcaca gactacccca cgctcacgct
    90481 cttccttgct gagctgagaa atagcataat aggcaccacg aattttaaaa gagcgaacac
    90541 gttgagcatt ttcctttttc aaataaatct tagcaccata cttctccgat aaataatgat
    90601 cgtaatccag tggagtattc acaaccacac cgttcaagac cttgtgagcc ttgattatat
    90661 cttttgaact taacatataa aacctctttt tctataaaaa acagtcacta atgactgttt
    90721 tttagttatt catctccgaa aacttcagta acactttcat ggtatttatg agccatacga
    90781 atcgaaaact ctttaggaag ttcataacga tttgtggaaa tccaatcata taaccattct
    90841 accaaacttt cttcactatc attacgaaag ttttcgcagt ccagtcattt aaacccgatt
    90901 ctttcaatcc agatgcaata atttgctcta tttgatataa accgccatct atcgtctcat
    90961 ttattctgcg aagaggacct tcaatatagg ataaagcttc tccgaatcta acagctgatt
    91021 taggtcctaa tgatttacca actatatttg ttaatgtttt ttatttctca aaatccattt
    91081 cgctatataa cgagcagatt tagtcgcacc agctctctca aacggagaat gaatttcaag
    91141 accttcttct ctagatattt gtgccaattt gaagaattgt tcaaagttca tatgcaacct
    91201 accatcttca aaattagcat catcataaat gttaattaca gcattttcat catacgacca
    91261 atctgcttta ttttggtctg ctagcactat taccgacggt gtaattacat tatacaacta
    91321 gaaccaataa taacgatgca atttttctca taatcttttt cataaaatca tctccagcgc
    91381 tatatatttc taattagtta tagattttga atgcatcatc gtcgttttta ccaacgaatg
    91441 gcattgcttt acgcaattct gcaccaactt tttcaatttc aaggttagct gcttgttcac
    91501 ggtaagcagt caattttgga cgtccagctt tatagtcatt tacaaagtca tttgcaaatt
    91561 taccattttg gatgtctgcc aagacagcct tcatattttc tttaacttgt tcagtgatta
    91621 cacgtagacc tgatacatag tcaccgtatt cagcagtgtt tgaaatagat tgacgcattt
    91681 tcttgaatcc accttcgtag atcaagtcaa cgatcaattt catttcgtga agaacttcaa
    91741 agtaagccaa ttctggagcg taacctgctt ctgtcaagac ttcgaaacct gcttcgataa
    91801 gggcagtcaa accaccacaa agtacagctt gttcaccaaa caaatcttct tcagtttctt
    91861 ctttgtaagt tgtttcaaga agacctacac gagccgctcc aacaccttta caccagtcca
    91921 tagcaatgtt tttagcattt cctgttgcat cttgatatac tgcataaaga gctggaacac
    91981 caaatccttc ttcgtaagta cgacgtacca agtgtcctgg tcctttagga gcacacatga
    92041 agacatctac atccgcagga actttgataa attcaaagtg gatgttgaaa ccatgggcaa
    92101 atccaactgc gtttccagct tccaagtttg gagcgatttc tgcttcgtac aattcttgtt
    92161 gaatttcgtc tggcgccaag atcatgataa catcagccaa cttagtagct tctgctacta
    92221 tgtaagtatc aaatccatct tcttttgctt tatcaaaaga tttacctgga cgtacaccga
    92281 taataacgtc acgacctgaa tcacgcaagt tttgagcatg cgcatgccct tgtgaaccat
    92341 aaccgataac ggcgattttt ttaccgtcaa gtgctgctac tttaacatct ttttcatatt
    92401 ccatttgaac tgtcatagct tttctctctt ttctattatt tattgccttt taggctggtt
    92461 taataaattt aagttggatt tttaatcgcg ggtaaatcca gttgcacccg ttcgagcaat
    92521 attgcgaata ccgtatgggc gaatgactcg caatagggct tcgctctttt ctgcatttcc
    92581 cgtcatctga atggtaatcg agcttggcgc tacgtctacc actgttgcac ggaaaggttg
    92641 aataatcgct aaaatctcag ctctcttctc agctggcgct gacatcttaa ccaaaatcac
    92701 ctcgcgctcc aaatgaggct tgtctgtaat atctcgaatg cgaatcacat caatctgacg
    92761 attgagctgt ttgatgattt gctccacttc atcatgagaa gcaacatcaa taataatagt
    92821 gatacgcgat acattcggat cttctgttgc tccaacagag atgctttcaa tattaacctg
    92881 acgacgagat aggacacctg taaagcgatt gaggactcct gaacgatttt gtagttttgc
    92941 tgttaacatt ctacgcatgg aactgcaccc ccaacatctc atgattactc ttaccagccg
    93001 gtaccattgg taacacctgt tccttacgag aaatatctac ctcaattagc ataggaacat
    93061 cctcagtgat gacttcaagg tcttgagcca aggtctcagg attgtcaaac ttatagtttt
    93121 taataccata agcctgcgcc atcaattgga aatcaggaag ggtatcaaag accgactctg
    93181 atgttctgcc ttcatagaag gattcctgcc actggcgaac cattccaagt gaatgattgt
    93241 tcagcataac caccttgatt ggcaccttgt aaatattcaa aatagccaac tcctggttgg
    93301 tcatttggaa accaccatcc ccaacaaaca agactacctc cttatctggg ttagcaattt
    93361 tagcaccgat tgctgctgga attccaaatc ccattgttcc caaaccacct gaagtcacta
    93421 actgacgttc attttggtag ggataatact gagctgtcca catttggtgt tgaccaacgt
    93481 ctgttaccac aatggcatct ccattcgtca attcaccaat tcgttcaata actgcttgcg
    93541 gttgaaccac acgctctttc ttgtcataag aacgaacacg attcttgtct ttagtgactt
    93601 tctcaatcca cttttcagta ttgttgtgaa ctgttggttc tgctagcaac atttgcaagg
    93661 ccttcttagc atctccaact acaggaatgt ctgcactgat aatcttgcca atctcagctg
    93721 ggtcaatatc aatgtgggca accttagcat tcttagcgaa agtcttagga ttccccgtca
    93781 aacggtcatc gaaacgagaa ccaatactaa tcataaagtc cgcttccgtc atggcaatat
    93841 ttgctgcgaa tgacccgtgc atgcctccca ttccaagaaa gagtgggtga ctcgttgcaa
    93901 tcgttccttg tcccaaaaga ctggttacca ctggaatttg atagcgttct gcaaattcat
    93961 ttagttccgt agcagcctca gcataactaa ttccaccacc agctaacaag actggctttt
    94021 tagccttgga caattgcttc aagattttct tgatttgcat atcattcggc tcaagagtcg
    94081 gctgataact tggtaaattc acttctggtg aataaatgaa gtctgtttct aaagcagata
    94141 tgtcttttgg taggtcaatt acaactggcc ctggacggcc tgtagttgcg atatggacag
    94201 cttccgtaat gatacgcgga atatcagctg tctcacgaac ttggtaattg tacttagtga
    94261 ttggcatggt aattcccacg atgtctgcct cctgaaaggc atccttccca atccctgctc
    94321 gcgccacctg acctgtaaag accaaaaggg gaacgctatc gctcatggca tccgcaatcc
    94381 ctgtaatggc atttgttgct cctggtccac tagtgacgac ggcaacaccc aactttccag
    94441 ttgatttggc ataaccttca gcttcatgca aacaaccttg ctcatggcgc cctagaatgt
    94501 ggcgaatgcc tttaaaatta tatatcgcat cataaaaagg caaaaccgca ccaccaggat
    94561 aaccaaagat ggtatcaact cctaaatcac gaagtgtttc caaaactagg tccgaccccg
    94621 tcttaggaga ttctaaactg attttctcca ttattcccct ttctttcctc ttaaaaataa
    94681 cttgttacta tcataccatt ttttcaaaat ttttcaagat aaaagaagaa attttctgaa
    94741 ttttctattt taacgtttat ttatgaatgt tatttttgtt tttattaaaa agataccgat
    94801 ttcatttact aaaaagaaaa aagaactgat ttctcagtcc ttcattaatc ttattccaca
    94861 ctaaataggt atgggtaaac aggttgttga ccttggtgaa tctcgacttc aacgtcttcg
    94921 aattcttcta cgatttcttg agcgatttca ttggcaagtt cttcgcttcc gtcttcaccg
    94981 acatagaagg ttacgatttc actatcttca tccaacatat gtttcaaggt ttcagtcaat
    95041 gtttggtgca tatcagggtt tgacacaaga atttttccat ccaccatacc tagattatcg
    95101 ttttcatgga tttctaagcc atcgatcgtt gtatcacgca cggctgttgt gacgcttccg
    95161 ctaacgacat cgctaagagc agctgtcata cgctcttggt tttcttcaat ggacttgctt
    95221 ggatcaaagg caagaagact tgtcatacct tgaggaagag tgcgagcctc taccactact
    95281 gctggttgct ccaaaacttc tgccgcagat tgagctgcca tgaagatgtt cttgttgttt
    95341 ggcaagaaga tgatgttacg ggcattgacc tgttcaacag ccttgataaa gtcttctgtt
    95401 gaagggttca tggtttgacc gccttcgata acataatcca cgccttgaga acagaagata
    95461 tctgctagac ctttaccagc caccacagca atcaaagcat actctttttc ttcagccgac
    95521 ttgataactt gagtagcttc tttctcaacc tgtgcttcgt gttggttacg catattgtca
    95581 acttttacct tgaccaagct accatatttg agaccttctt gcataacaag tcctggatct
    95641 tctgtatgaa catggacttt gacaatttca tcatcgttaa caacgaggag agaatcccca
    95701 agctcatcca agtagttacg gaattcatcg tagtcaaaat ctttagcata ggttggacct
    95761 tgcttaagag ctaccatgat ttcagtacag taaccaaacg tgatgtcctc agttgctacg
    95821 tgaccagcta cagacttatg atgctctaca ttgatcatct cactcatgtt ggcaggagtc
    95881 gctacaaagt cctcagatgc aatatattcg ccagtaaggg ctgaaaggaa accttcgtag
    95941 atgaagacca atccttgacc acctgagtcc acaacgccaa cttctttcaa tactggaagc
    96001 atgtctggtg ttttagctag agctgtttta gcaccttcca aggctgcgcg catgacttca
    96061 acagtgtcat ctgtttgctc agcttttttc ttagcaccga tagcagctcc acgagaaact
    96121 gtcaaaatcg ttccttcaac aggtttcatc actgccttat aggcaacttc cacacctgat
    96181 tggaaggcca gagccaagtc ttgacctgtt aactcgtctt tatccttgat agcttgggaa
    96241 aatccacgga aaagctgaga cgtaatcact cctgagttcc cacgcgcacc catcaaaagc
    96301 cctttggcaa gaatgctcgc tacttctcca actgtagaag ctggcttgtc tgcaacttct
    96361 ttagcaccat tttcaatggt cattcccata tttgtcccag tatctccatc tggaactgga
    96421 aagacgttta atgaattgac atattcagct tgcttattca agcgagttga tgcagcctgc
    96481 accatttctt gaaataagct agtagtaatt tttgacacgg ttattctcct acaactttga
    96541 tattttgaat gtagacattt acagtctgag cagtaattcc aagctggttt tccaagctaa
    96601 aggcaacacg ctcttgaatg ttttttgaca cttcactaat ctttgttccg tagcttaaca
    96661 cggtatatac atcaactgca atactgccat cttcggctgc ctttacgacg acacctttag
    96721 aataattttc cttacctagc agggcttgga aattatcttt gagggcattt ttactagcca
    96781 taccgaccac accaaaaatc tcagttgctg ctccacctac gacggttgca atcacttcat
    96841 ctgttagttc gatttgacca tcttttgtat taatttttac agtcatcctt tttacctcaa
    96901 ctagttgata ctctatttta tcatatttca gcccaagtgt aaaagcagaa tgatgtatca
    96961 gcggatattt actctatttt tcaaacgatg ttatacccac aataaaagaa aaaagaccct
    97021 aaggtctcct ttgcttttat tattaaacgc gttcaacttt acctgatttc aaagcacgag
    97081 ctgaagccca aactttttta ggtttaccat cgataagaac agtaactttt tgaaggtttg
    97141 gttttacggc acgttttgtt tggttcatcg cgtgtgaacg gttgtttcct gatacagtct
    97201 tacgacctgt aaagtaacat actttagcca ttgtgttttc ctcctattag atctaatata
    97261 gcggatgtgc tagcaccaca taccgtacta tgttatcaca ctttcttgtt ttttgcaagg
    97321 gaattggaag attttttatt tgtgtcttaa atcaggtctt gcgtgacatt ttctgctctc
    97381 cacatgccat cgttgattaa cagaacacca gaattaaaat tatgtgtata aaaatcatct
    97441 ctaactgcag ctaagggtat agccgtcaag tccaaatccc acagctcatc tatcgatttt
    97501 cttacaacaa tatctgaatc caaatacagt acacgagact cgcttacata ctttggaata
    97561 aaatacctaa aaaagccgca tatgaaagtc cctcaaaggg gagacgataa cctttcagaa
    97621 tattactgtc aatctaaaca ttcacaatct cactattcaa agtctctagt cttttttcca
    97681 tcaattggaa ccattctcgc ggaaggtcat cattaaaaac ataaaactta agattataat
    97741 gatgaacaca aagagatttt attgttgttt caactttatc catataagca ttatctgcac
    97801 ctaagacaat cgcttttttc tcttctttca ctttttatct catttctttt tattcccatc
    97861 atattattcc catcatatgt ttctacgtaa ccattatttt cgcctattcg ttcgtaaaac
    97921 tataccagtg gagattttag atgaagtccc attacggttt acaattttta cattacgaca
    97981 cggagtttta caaatcgatt tcatttgcca aacgtagtta gtaaggcagt tagctaggct
    98041 acctactttc tgctacgacg gaaaaatcca caaatcaata ccattcgtgg atttttccta
    98101 gtgaagcgtt taggtaagcc gccatagcgg ttaccgatta ttagattacg acacggagtt
    98161 tggcaaatcg attctatttg ccaaacgtag ttagtgactc agtaccaaca atttggaact
    98221 ttagttccaa attgttggta ctgagtcaca tcttctcctc taactctacg tctggatact
    98281 tgtccgcaaa ccagcggagg gcaaagtcat tttcaaagag aaagactggt tggtcaaaac
    98341 ggtctttggc taagatattg cgacttgacg acatccgttc atccaagtcc tcaggcttga
    98401 tccaacgaac ggtcttttta cccattgggt tcataactac ttccgcattg tactcacctt
    98461 ccatgcggtg tttaaagact tcaaactgga gttgacctac agcgcctagc atgtactcac
    98521 ctgtttggta attcttataa agctgaacgg ctccttcttg caccaattgc tcaatcccct
    98581 tgtggaagga tttttgcttc ataacattct tagcagaaac tttcatgaaa atttcaggag
    98641 taaaggttgg cagtggttca aattcaaact tgtttttacc aactgtcaag gtatccccaa
    98701 cttgataagt acctgtatcg taaaccccga taatatcacc tgccacggca ttggtcacat
    98761 tctcacgact ttccgccata aactgagtaa cattagacag tttagccccc ttaccagtac
    98821 gagggagatt aacactcatg ccgcgctcaa attcgccaga tacgatacgg acaaaggcaa
    98881 tacggtcacg gtgacgaggg tccatgttgg cttggatttt aaagacaaag cctgagaaat
    98941 ccttgtcata aggatccaca atttcaccat ctgttttctt gtgaccatgt ggttctggag
    99001 caaacttgag gaaggtttca aggaaggtct gcacaccaaa gtttgtcagg gctgaaccga
    99061 aaaagacagg cgtcaattct ccagccagaa tagcttcctc tgaaaactca ttcccagctt
    99121 catttaaaag ctcaatgtca tccttgactt gatcgtagaa aggattgcta ccaaagagtt
    99181 tgtccccgtc ttctagactg gcaaaacgct catccccttt gtaaagctct aaacgttggt
    99241 tatagaggtc atacaagccc tcaaaggctt tccccatccc gataggccag ttcatagggt
    99301 agctagcaat gcccaagatt tcttccaatt cttgcaagag atccaaaggc tcacgaccgt
    99361 cacgatccaa cttgttcata aaggtaaaga ctggaatgcc acgatgtttc acaacctcaa
    99421 acagtttctt tgtttgagcc tcgatcccct tggcagagtc cacgaccatg accgcagcat
    99481 ccaccgccat caaggtacga taggtatctt ctgagaagtc ctcgtgccct ggcgtgtcta
    99541 agatattcac gcgcttgccg tcgtagtcaa attgcataac agatgaagta acagaaatcc
    99601 cacgttgctt ctcgatatcc atccagtcag atttagcaaa agtccctgtt ttcttccctt
    99661 ttaccgtacc agcctcacga atctcacccc caaagtagag taactgctca gtgatggttg
    99721 ttttccccgc gtccgggtgg gaaataatgg caaaggtacg acgtttctta atttcttctt
    99781 gaatattcat aagttctctt tctttgattc tctatttttc ttgtttcaat agctgagaat
    99841 gatttttaca ttggatttta ccattccttt caacactcca ttatatcgga ttttagcatt
    99901 tttttcaatt tctatttctt ttcacttccc cctcccttat ttataggaaa atatggtaaa
    99961 atagaacaga ctaaaaatca tcatttcacg aaaggatgca agatgaaaat tacgcaagaa
   100021 gaggtaacac acgttgccaa tctttcaaaa ttaagattct ctgaagaaga aactgctgcc
   100081 tttgcgacca ccttgtctaa gattgttgac atggttgaat tgctgggcga agttgacaca
   100141 actggtgtcg cacctactac gactatggct gaccgcaaga ctgtactccg ccctgatgtg
   100201 gccgaagaag gaacagaccg tgatcgcttg tttaaaaacg tacctgaaaa agacaactac
   100261 tatatcaagg tgccagctat cctagacgat ggaggagatg cctaatgact tttaacgata
   100321 aaactattga agagttgcac aatctccttg tctctaagga aatttctgca acagaattga
   100381 cccaagcaac acttgaaaat atcaagtctc gtgaggaagc cctcaattca tttgtcacca
   100441 tcgctgagga gcaagctctt gttcaagcta aagccattga tgaagctgga attgatgctg
   100501 acaatgtcct ttcaggaatt ccacttgctg ttaaggataa catctctaca gacggtattc
   100561 tcacaactgc tgcctcaaaa atgctctaca actatgagcc aatctttgat gcgacagctg
   100621 ttgccaatgc aaaaaccaag ggcatgattg tcgttggaaa gaccaacatg gacgaatttg
   100681 ctatgggtgg ttcaggtgaa acttcacact acggagcaac taaaaacgct tgggaccaca
   100741 gcaaggttcc tggtgggtca tcaagtggtt ctgccgcagc tgtagcctca ggacaagttc
   100801 gcttgtcact tggttctgat actggtggtt ccatccgcca acctgctgcc ttcaacggaa
   100861 tcgttggtct caaaccaacc tacggaacag tttcacgttt cggtctcatt gcctttggta
   100921 gctcattaga ccagattgga ccttttgctc ccactgttaa ggaaaatgcc ctcttgctca
   100981 acgctattgc cagcgaagat gctaaagact ctacttctgc tcctgtccgc atcgccgact
   101041 ttacttcaaa aatcggccaa gacatcaagg gtatgaaaat cgctttgcct aaggaatacc
   101101 ttggtgaagg aattaaccca gaggttaagg aaaccattct aaatgccgct aaacactttg
   101161 aaaaacttgg tgctattgtc gaagaagtca gccttcctca ctctaaatac ggagttgccg
   101221 tatactacat catcgcttca tcagaagctt catcaaactt gcaacgcttt gacggtatcc
   101281 gttacggcta tcgcgcagaa gatgcaacca accttgatga aatctatgta aacagccgaa
   101341 gccaaggttt tggtgaagag gtaaaacgtc gtatcatgct gggtactttc agtctttcat
   101401 caggttacta tgatgcctac tacaaaaagg ctggtcaagt ccgtaccctc atcattcaag
   101461 atttcgaaaa agtcttcgcg gattacgatt tgattttggg tccaactgct ccaagtgttg
   101521 cctatgactt ggactcactc aaccatgacc cagttgccat gtacttggct gacctcttga
   101581 ccatacctgt aaacttagca ggtttccctg gaatttcgat tcctgctgga ttctctcaag
   101641 gtctacctgt cggactccaa ttgattggtc ccaagtactc tgaggaaacc atttaccaag
   101701 ctgctgctgc ttttgaagca acaacagact accacaaaca acaacccgtg atttttggag
   101761 gtgacaacta atgaactttg aaacagtcat cggacttgaa gtccacgtag agctcaacac
   101821 caattcaaaa atcttctcac ctacttctgc ccactttgga aatgaccaaa atgccaacac
   101881 taacgtgatt gactggtctt tcccaggagt tctaccagtt ctcaataaag gggttgttga
   101941 tgccggaatc aaggctgctc ttgccctcaa catggacatc cacaaaaaaa tgcactttga
   102001 ccgcaagaac tacttctacc ctgataatcc caaagcctac caaatttctc agtttgatga
   102061 gccaatcggt tataacggct ggattgaagt cgagctagaa gacggtacga ccaagaaaat
   102121 tggtatcgaa cgcgcccact tagaggaaga cgctggtaaa aacacccacg gtacagacgg
   102181 ctactcttac gttgacctta accgccaagg ggtacctttg attgagattg tatctgaagc
   102241 cgatatgcgt tcgccagagg aggcctatgc ttatctgaca gccctcaagg aagttatcca
   102301 gtacgctggc atttctgacg ttaagatgga agaaggttct atgcgtgtgg atgccaacat
   102361 ctcccttcgc ccttatggtc aagaaaaatt cggtaccaag actgaattga agaacctcaa
   102421 ctccttctca aacgttcgta aaggtcttga atacgaagtc caacgccagg ctgaaattct
   102481 tcgctcaggt ggtcaaatcc gccaagaaac acgccgttac gatgaagcta acaaaacaac
   102541 catcctcatg cgtgtcaagg aaggggctgc tgactaccgc tacttcccag aaccagacct
   102601 acccctcttt gaaatttctg acgagtggat tgaggaaatg cagactgagt tgccagagtt
   102661 tccaaaagaa cgtcgtgcgc gttatgtatc tgaccttggt ttatcagact acgatgctag
   102721 tcagttgact gctaataaag tcacttctga cttctttgaa aaagctgttg ccctaggtgg
   102781 tgatgccaaa caagtctcta actggctcca aggggaagtc gctcagttct tgaatgctga
   102841 aggtaaaaca ctggaacaaa tcgaattgac accagaaaac ttggttgaaa tgattaccat
   102901 catcgaagac ggtactattt catctaagat tgccaagaaa gtctttgtcc atctagctaa
   102961 aaatggcggt ggcgcgcgtg aatacgtgga aaaagcaggt atggttcaaa tttcagatcc
   103021 agctatcttg atcccaatca tccaccaagt ctttgccgat aacgaagctg ctgttgccga
   103081 cttcaagtca ggcaaacgta acgccgacaa ggcctttaca ggattcctta tgaaggcaac
   103141 caaaggccaa gccaacccac aagttgccct taaactactt gcacaggaat tggcgaagtt
   103201 gaaagaaaac tagacagaac aaaaccagcc ctaaggttgg ttttttcttg acaaatagaa
   103261 agaaaacgtt tacaatattg cgtgtaaagt ttccaaacaa gaaaactaaa aatcgcaaca
   103321 ataaggagtt atttatatgg ctacaatgaa ggcagctcgc tggcatgcag cgaaagatgt
   103381 tcgtattcaa gaaatagaag ttcctgaagt acttccgcac caagtaaaag ttgcagttaa
   103441 gttcacagga atttgtggta ctgacctcca tgaattttta gatggaccta tctttatccc
   103501 aacagatgag cacgtctatt ctggtcaaaa agcaccggta acactgggac atgaattttc
   103561 tggtgaaatc atagaagtcg gaagcgatgt tacctgtgtt aaagttggtg atcgtgttgc
   103621 tgtggaacca attctagcta aaaataactt agttggtgat tataatttgg atccaaacct
   103681 taattttgtc ggtttggctg cagacggtgg atttgccaaa tattgtgttt tagacggtga
   103741 cttagtacat gtcattccag atagcttgag ctatgagcaa gctgctctta ctgaacccgc
   103801 tgctgttgca gtctatgctg ttcgtcaatc ttctttgaag gctggcgata cagctgttgt
   103861 ctttggttta ggcccgattg gtctattaat tgtagaagct cttcgtgcag ctggtgcttc
   103921 taagatttat gctgttgaac tatcacctga acgtcaagca aaagctgaag agttaggagc
   103981 tatcgttgtc cgtccggaag aaggtgaaac agctgttgaa gctattcatc gtttaacaaa
   104041 cggtggtgta gatgtttctt atgaagtaac gggtgtgcca gtagttttag gacaagcctt
   104101 agctgccgta cataaagcag gtgagtgcat ggtggtctct atctgggaac gagaagcaaa
   104161 tattaatccg aatgaatttg caatccaaga aaagacacta aaaggaatca ttgcttatcg
   104221 tcatatcttc cctaaagtat tagaattgat ggaacaaggc tacttctccg ctgaaaaatt
   104281 agttactaag aaaattaaat tggaaaatat cgtcgaagaa ggctttatcg aattaactca
   104341 agataagtca caaattaaaa ttttggtaga accagaataa aaaatcaatc tttttaagac
   104401 aatactaaca ggtcggagta aacttacttc ggccttttga aatataatac tcttcgaaaa
   104461 tctcttcaga ccacgtcagc gtcacattac cgtactcaaa tacagcttgc ggctagcttc
   104521 ctagtttgct ctttgatttc cattgagtat gagaagaaat atagtggata ctctttaaca
   104581 ttaaccactc cacctgacta gccaatattc tttttcgctc ctaccaactc ccaataacta
   104641 ttttggcttt atttccagag tattttatgg taaaatgaag agtaataata tttattaaag
   104701 aggtaaaaac atgattgaag caagtaaatt aaaagctggt atgacctttg aaacagctga
   104761 cggcaaattg attcgcgttt tggaagctag tcaccacaaa ccaggtaaag gaaacacgat
   104821 catgcgtatg aaattacgtg atgtccgtac tggttctaca tttgacacaa gctaccgtcc
   104881 agaggaaaaa tttgaacaag ctattatcga gactgtccca gctcaatact tgtacaaaat
   104941 ggatgacaca gcatacttca tgaatacaga aacttacgac caatacgaaa tccctgtagt
   105001 caatgttgaa aacgaattgc tttacatcct tgaaaactct gatgtgaaaa tccaattcta
   105061 cggaactgaa gtgatcggtg tcaccgttcc tactactgtt gagttgacag ttgctgaaac
   105121 tcaaccatct atcaaaggtg ctactgttac aggttctggt aaaccagcaa cgatggaaac
   105181 tggacttgtc gtaaacgttc cagacttcat cgaagcagga caaaaactcg ttatcaacac
   105241 tgcagaagga acttacgttt ctcgtgccta atctctagaa agaggtcatt ctatgggaat
   105301 tgaagaacaa cttggcgaaa tcgttatcgc cccacgtgta cttgaaaaaa tcattgctat
   105361 cgctactgca aaggtagagg gtgttcactc tttttcaaac agatcagtgt ctgataccct
   105421 ttcaaaactt tcactcggcc gtggcattta tcttaaaaac gtggacgaag aactcacagc
   105481 agatatctat ctctaccttg agtacggagt aaaagttcct aaggtagcgg ttgctatcca
   105541 gaaagctgtc aaagatgccg tccgtaatat ggctgatgta gaactcgctg ctatcaatat
   105601 tcacgttgca ggtatcgtcc cagataaaac accaaaacca gaattgaaag atctatttga
   105661 cgaggacttc ctcaatgact agtccactat tagaatctag acgccaactc cgtaaatgcg
   105721 cttttcaagc tctcatgagc cttgagttcg gtacggatgt cgaaactgct tgtcgtttcg
   105781 cctatactca tgatcgtgaa gatacggatg tacaacttcc agcctttttg atagacctcg
   105841 tttctggtgt tcaagctaaa aaggaagaac tagataagca aatcactcag catttaaaag
   105901 caggttggac cattgaacgc ttaacgctcg tggagagaaa cctccttcgc ttgggagtct
   105961 ttgaaatcac ttcatttgac actcctcagt tggttgctgt taatgaagct atcgagcttg
   106021 caaaggactt ctccgatcaa aaatctgccc gttttatcaa tggactgctc agccagtttg
   106081 tagcagaaga acaataaaaa gaaaaagtgt ttgatagata tcaaacactt tttctttgcc
   106141 tcccactatc taaaaaaatg ataatagata taattgtaaa caaaaatcca gataggtttt
   106201 gcatgattga gaaagttaaa aaaactatgg cagagaatcg ttaatctcag attgtcggta
   106261 gaacgataaa caaaggcaaa aaagaaacca atcagactat aatataataa actaattgga
   106321 tctctgtgag atagtatcaa atgactaagc ccaaagataa ggcctgataa gatgacatct
   106381 aaataatact tggactaggg aaagaaggta ttcataaaat accctctatc aagagtctcc
   106441 tcaaaaacag gaccgatgat tacaggcagg acaaaagata agatagtcga taaaaaggtt
   106501 ggttgtccat ttgaaagaac cacggtaaaa tactcatcat gaatattcct atgattaatc
   106561 aaatgagcat agcgtgccca aaaattaccg agaatctgat aaaccacata agttgcaaat
   106621 aaggagaaga caaatgacca gttccagctc tttttctcaa agataaagag catctttttc
   106681 ttttttaacc tccaaattaa tagaaaagga aacttcccac taatcccact gttaaaataa
   106741 gagaatagac atcagctcct aaccctaaaa tgatcgtcac atacaatcca attgtttgtg
   106801 gtaagtaaat aggtagatag taaaataata agcaaaaata ttccaaattg tcttagtttc
   106861 tttgtgtttc tcatcgtact tttttgaaag attaccctgt tcggaagccg tacttccaag
   106921 catctatata agaattaagt gccccttgcc tcatataagg agcaaattct ctataatata
   106981 accatctact atatccatct tcccaaacag caagaccacc tgaagtttgc tccaagtcct
   107041 cagttgaaat aactgtaaat gtttctgtac ctgtcattgc aagtaccttc ttaaaataga
   107101 ttgttgtagg ctcacattta tagtatattt ctttttttgt ctattttata gtctatctcc
   107161 tcaactgtca atttttcaac ctgaattgca tttttccata aaaaatgaga cctttctagt
   107221 ctcatttagt cattcttagt attttctaaa tctttgatag cgttcttcca gcaactcttc
   107281 tagcgatttt tgtgaaagtc tagctagctc cgtttggagt tcttttttaa cattcttaat
   107341 caattcttta ctagaaagtc ccgtttcaga gatcacctta tccaccacgt ccatttctaa
   107401 caactcgtgt gaagtgattt tcatcagttc tgccgcttcc atggcacgac tgccgtcctt
   107461 ccatagaatg gaagcaaagc cttctggact gagaatagca tagatagaat tttccagcat
   107521 ccagacacgg tctgcgactg ctagagccag agccccacct gaaccacctt caccgataat
   107581 gatagcgata ataggaactc tcagatcact catttccatg agattgcgag caatggcttc
   107641 tccctgtcca cgttcttccg ctcccacacc aggataggca cctgctgtat tgataaaggt
   107701 cacaactgga cggccaaact tttcagcctg tttcatcaaa cgcaaggcct tgcgatagcc
   107761 ttctggatgc ggttgtccaa aattccgctt gaggttatct tgtaaactct tgcctttttg
   107821 gataccaacc actgttacag cttgatcacc aagccagcca ataccaccaa caactgcacc
   107881 atcatcacga aaagaacggt caccgtgtaa ttggataaag tcatcaaaaa tgcctgtcgc
   107941 aaagtccaaa gttgtcaagt gactctgctc acgcgcttct ctgactattt ttgcaatatt
   108001 catctaggac tccctccatg caatctgact aggctagcaa tcgtatctgg caaatctctt
   108061 cttttaacga tagcatccac aaagccatgt tccaatagga attctgcctt ttggaaatcc
   108121 tcaggcaagc tttcacgaac cgtattttca atgacacgac gcccagcaaa accgaccaag
   108181 ctctgtggtt cagccagaat aatatcgcct tccatagcga aagaagctgt cacaccacca
   108241 gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag catttgaatg gcgtttaact
   108301 gctgcagaaa tcttggccat ctgcatgaga ctcatgattc cttcctgcat acgggctcca
   108361 ccagaggctg tgaagagaac aactggcaac tgttcaaccg tcgcatactc aaataagcga
   108421 gtgatttttt cacctacaac cgtacccata gaagccatga taaagttgga atccataatc
   108481 ccaagagcca cagtctgacc tttaataaga gcagttcctg tcacaacggc ttcatccaga
   108541 ccagtttttt cacgcatagt tgctagtttc ttttgataac cagggaaatg caagggatcc
   108601 ttgctttcaa tccctgtaaa caattccttg aaggttccca tatcaatcgt caaaaccaag
   108661 cgttcttggg cagaaatacg aaaggtatag ctacagtgtg gacagatacg ctcacttccc
   108721 agatccttct gatagatggt atgcttacaa cccggacact gagaaaataa ttcatctgga
   108781 acttctggct tggcttgagg tttttcccta atcgaacgat tgggattgat tcgaatatac
   108841 ttatcttttt tactaaatag agccattgat tccccttttc ggtttaaact cttgaagtca
   108901 ttttattctt tttcttgata cttgggtaaa aaggtttcca tcaagaagga agtatcataa
   108961 tccccagcaa tgacattgcg atctgaaatg aggtcaagct ggaaatctgc atttgtctgc
   109021 actccttcaa tctctaattc ataaagggca cgttgcattt tcatcaaagc atcaaaacga
   109081 ttttcgccgt gaacgatgat tttagcaatc atactatcat aataaggcgg aatggtatag
   109141 cctggataaa ctgctgaatc cacgcgcaag ccaactccac cacttggcag atagagatta
   109201 gtaatcttac ctggacttgg agcaaagtta aaggctgggt tttctgcatt gatacgacac
   109261 tcgatggcat gaccgcgtag gacaatatct tcttgcttaa cagacaaagg ctgacctgct
   109321 gcaatgcgaa tttgttcctt aacgatatcc acacctgaaa caaactctgt tactggatgt
   109381 tctacttgta cacgagtatt catctccatg aaatagaaat tgccacttgc ttcatcaaga
   109441 agaaactcaa tggtccctgc attctcatag ccaacagact ctgcagctcg aacagccgca
   109501 gcaccgattt catggcgcaa cgtttttccg attgcaatcg aaggactttc ttccaaaacc
   109561 ttttggttat tccgttgaag agaacaatcc cgttcaccca agtgaatcac atgtccatgt
   109621 tcatctccta ggatttgaac ctcgatgtga cgagctggat agataacccg ttcaatgtac
   109681 atggcaccat tgccataatt ggccttggct tcactagagg cagtttcaaa ggcgaaaacg
   109741 aggtcttctg ttttttcaac cttacgaatt cctttaccac ctccacctgc tgaagccttg
   109801 agcataacag gatagccaat tttttctgca acaatcaaag cttcctcaga gttatgcact
   109861 tctccatctg aacctggaat gacaggcaca cctgctttga tcatctgagc acgcgcattg
   109921 atcttgtctc ccatcatatc cattacatga ccagatggac cgataaactt gattcccacc
   109981 tcttcacaca tggtcgcaaa tttggaattt tcgctgagaa atccaaaacc tgggtgaatg
   110041 gcttctgcct cagtcaagac tgcagctgat agaaccgcat taatattgag ataagactct
   110101 gttgccttgc caggaccgat acaaactgct tcatctgcca aaagcgtatg aagggcttcc
   110161 ttatcagcag ttgaataaac cgccaccgtt gcgatcccca attcacgtgc cgcacggata
   110221 atacgaaccg caatttcacc acgattggca attaaaattt ttcgaaacat ggagaacctc
   110281 cttagttccc aattgcaaaa gtaagggtac cactggctgc aagcttgcca tccacttcag
   110341 cctttgcttc aaccacagct atggtgccac gacgttttac aaaagtcgct gtcataacca
   110401 attggtcgcc tggtacaact tgcttcttga acttaacctt atccatacca gcgtaaaaga
   110461 ccagttttcc tttattttca ggttttgata actccaacac accagcagtt tgcgccaagg
   110521 cttccataat cagaacacct ggcataactg ggtattgagg aaagtggccg ttaaagaaag
   110581 gctcgttgat ggtcacattt ttgatagcaa caatggtatc ctcgctcacc tccaagacac
   110641 ggtccactag aagcatagga taacggtggg gaagggcttc tttgattcct tgaatatcga
   110701 tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt tcttcgttag agacgagaat
   110761 ttccgttacc acaccatcct taggagctgg gatttcattc atgactttca tggcttcgat
   110821 aattaccaat gtttgacctt ttttgacact atcaccaact gtaacgaagg caggtttatc
   110881 tggtccagca gccaagtaaa ccactccaac aagtggactc tctacaagat ttccctcagt
   110941 agccacactt gcttcagctg gagctggaac ttcttctgct acagtctctg ctggagcaga
   111001 tgtaggagct actggactcg gtgttgctag aacgggtgct ggagcgactt gagttgcaac
   111061 ttcaggcaca ggtctcgctt cattcttgct aaactgcaac tcatccgtcc catttttata
   111121 agaaaattct ctcaaacttg actggtcaaa ttgagtcatc aagtctttaa tatcgtttaa
   111181 attcatactt atctattctc ccaacgtttg aaagcaagaa ctgcattgtg gcctccaaaa
   111241 ccaaaagtat ttgaaatagc gtatggaatt tctttctcca agccttgtcc ataaacgaca
   111301 ttagcttcga tataatctga tacttcactt gtcccagctg tcattggtac aaagttatga
   111361 cgcatagctt cgatggtgac gatagcttct actgcacccg cagcccccag caaatgtcct
   111421 gtaaaagact tggttgatga tacaggtact tccttaccaa gaacagctac gatagcacca
   111481 ctttctcctt tttcattggc aggagttgac gttccgtgag cattgacata ggctacttgc
   111541 tctggagaaa tctcagcttc ttccaaggct agtttgatgg ccttgatagc tccctgacct
   111601 tctggatgtg gagaagtcat gtggtaggca tcacaagtat ttccgtaacc aaccacttca
   111661 gccaggatag tagctccacg tttttcagcg tgttcaagac tttctagaac caacatccct
   111721 gaaccttcac ccataacaaa cccattgcga tccttatcaa atgggatcga agcacgagtt
   111781 ggatcctctg tagtagagag agctgttaag gcttggaaac cagcgatggc aaaaggtgtg
   111841 atagaagctt ctgttcctcc caccaacatc acatcttgga aaccaaactt aatggagcgg
   111901 aaggcatccc caatcgcatc atttgatgaa gagcaggcag tattgataga tttacaaaca
   111961 ccgtttgcac caaaacgcat ggctacattc ccagaagcca tatttggtaa agcttttgga
   112021 agagtcattg gtttgacacg tttgggtcct ttttcatgaa gacgaagtac ctgatcttca
   112081 atttccttga ttccaccaat accagatgca acgataacac caaaacgatc cctattaaga
   112141 gcctctacat caagattggc atgatttaca gcctcttggg ctgcatacaa ggcatataaa
   112201 gaatagttat caaaacggtt ggtatctttt tttacaaagt atttatcgaa cggaaaatct
   112261 tggatttctg ccgcattatg cacatcaaag tcactatgat caaattttgt aatgccacca
   112321 atgccgattt tcccagttgc taaactattc caaaattctt ctggtgtatt tccgattgga
   112381 gatgttactc cataacctgt taccactact cgatttagtt tcattctttt ctcctctagc
   112441 tttcgctaca tacttaagcc gccatcaatg gcaatcactt gaccagttag ataatcttgg
   112501 cctgctaaaa atactgtcaa atctgcaacc tgctctgcct gcccaaattc tttcatcgga
   112561 atctgagcta gtgtagcttc cttaatctta tctgataaga tagctgtcat atcagactca
   112621 atcattcctg gagcaatcac attgactcgt atattccgac tagcgacctc gcgtgccaca
   112681 gacttggtaa agccaatcaa gccagcctta gaagcagcat agttagcttg accaatattc
   112741 cccatcaaac caacaacact agacatatta atgatagcac cttctctggc tttcatcatc
   112801 ggtttcaaga ctgattgtgt catattaaag gcaccagtca gattgacctt gagcactttt
   112861 tcaaaatctg cttctgtcat cttgagcata agagtatctt gggtaatccc tgcattgttg
   112921 accaaaacat ctactgaacc cagttctgca atagcttgat caatcatacg cttagcgtct
   112981 gcaaaatctg atacatctcc tgaaatggga accaccttga taccatagtt tgaaaactca
   113041 gcgagcaatt cttctgagat taccccacga ctgtttaaga caatgttggc tcctgcttga
   113101 gcaaacttgt gggcgatggc aagaccaatt ccacgactcg aacctgtaat aaagatattt
   113161 ttatgttcta gtttcatttt tttcctttca aaacttctac ttattttagt ctatttttct
   113221 aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta agtgagcagt ttgatcaatt
   113281 tttttaacaa aacctgacaa gactttccct ggtccaatct cgataaagtt gcttatgcct
   113341 gcttcttgca tgaccccaat actttcatag aaacgaacgg gttccttgac ctgacgcgtc
   113401 aagagctgag caatgtcctc tttttgcatc acagcagctt ctgtattgcc gactagggga
   113461 caagtaaaat ctgaaaaact tacctgagct agagtttcag ctagtttctg gctagcaggt
   113521 tcaaggagag cggtgtgaaa gggacctgac accttaagag gaatcaagcg tttggcacct
   113581 gcttcttgca aaagttcaac cgctcgatca actgcaacca cttctccagc aatgacgatt
   113641 tgtgcaggtg tgttatagtt ggctggagta accactccaa gttcagaagc tttttgacag
   113701 gcttcttcaa tgacctctac tggcgtattg agaactgcta ccatcttgcc agagtcagca
   113761 ggagccgctt cttccatata ggctccacgc ttagctacca aggcaaccgc atcttcaaaa
   113821 tccaaggcgc cgcttgacac caaggcagag tattctccaa gagacaaacc agcaaccata
   113881 tcaggctgat agcccttttc ttgcaataaa cggtagatag caaccgaagt cgctagaatg
   113941 gctggttgcg tatagcgggt ctgattgagt ttgtcttctt ccgtatcgat gagataacgc
   114001 aaatcataac cgagcacctg actcgctcga tcaatcgttt ctttaacaat cggatactga
   114061 tcatagaaat cccgtcccat ccctagatac tgggcacctt gaccagcaaa taaaaaggct
   114121 gttttagtca tttcttacaa ctcctgtcca gcgagaggct tcttcttgaa ttttcttagc
   114181 ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt tcttctttag aaacaagccc
   114241 tgcgatttga cctgccatga cagagccacc atccacatca ccgtgaacaa ctgctttggc
   114301 tagggcacct gctcccattt gttcaaagat ttctaaatca ggatcttcct gcttaaaggc
   114361 atctttttca gccagttcaa aatctctagt caactgattt ttaatagcac gaacagcatg
   114421 accaaagtgc tgagctgaaa tcgtagtatc aatatccctt gcttttaaaa ttttctcctt
   114481 gtagtttgga tgggcattcg actcttttgc aactacaaac cgtgtcccca cctgtacagc
   114541 ctctgcacct agcataaagc cagccgcagc accttcacca tccgcaattc ctcctgcagc
   114601 aataacagga atagatacag ctgtggctac ctgtcgcacc aaggtcatgg ttgttaattt
   114661 accgatatgc cccccagctt ccattccttc tgcaataaca gcgtctgcac cgattttttc
   114721 catgcgttta gctaaagcga cactaggaac aacaggaata acgattatcc cagcttcatg
   114781 gaaacgttcc atatacttgc ttggatttcc tgctcctgtt gtgacaactt taacaccttc
   114841 ttcaataacg agatccacga tatcttccac aaagggagat aagagcatga tgttgacccc
   114901 aaagggttta tcagtcaatg atttgatttt atcaatattg gccttgacaa cttctttcgg
   114961 ggcatttccc ccaccgataa ttcctaatcc tccagccttg gaaacagccc ctgccaaatc
   115021 accatcagca acccaggcca tccctccttg gaaaatagga tagtcaatct tcaataattc
   115081 tgtaatacgc gttttcatag tgcctccaac cttccttgct tacgtaatag ttcgatttca
   115141 ccataatttg acagtcaaac tattacctaa acaagaggga gtgggtttct ccctactcct
   115201 tctactaata ttctgcttat tttgcttgct cttcaacgta agcaaccaag tcaccaactg
   115261 ttttcaagtc attttctgct tcgatttgga tatcaaaagc atcttcgatt tctgagatta
   115321 cttggaacaa gtccaatgaa tctgcgtcca aatcatcaaa agttgattca agtgttactt
   115381 ctgatgcgtc ttttccaagt tcttcaacga taatttcttg tactttttca aatactgcca
   115441 tgataggact cctttaaaat aaatagtttt tttataacaa tgtgttcacc acatgattac
   115501 ctaaattgta agaatgagcg tgccccaggt caagcctcca ccgaagcctg atagaagaac
   115561 agtctggcta ccatctaaag ggatgagacc ttgttctaca cactctgaaa gtaaaatcgg
   115621 gatactggct gcactggtat tgccatattc catcatattg gctggaagtt tggctcggtc
   115681 aacaccaatt tttctagcca tcttatccaa aatacggtca ttggcttgat gaagtagcag
   115741 ataatccaag tctgtcacct ctataggaga ttcatcaata gtctgcttga tagacttggc
   115801 tacatctcga atggcaaaat caaagactgt gcgtccatcc atcttcaaaa atgaatctgc
   115861 actttcttga tctgaaaatg gagaatgcaa acctgaatgc ccataagtta aacactcgct
   115921 gcgacttcca tcgctattga gactctcagc taagaaatgc tcttgctcgc tagcttctaa
   115981 caagacacca ccagcaccat ctccaaacaa cacagctgtt gatcgatccg accaatcgac
   116041 tgccttagag agggtttcac taccaatcac caagcctttt tgaaagcgac cagaagcgat
   116101 aaacttttca gcagttgaaa gagcaaatac aaatccactg caagctgcgg ttaagtcaaa
   116161 agcaaaggct ttattagcac caatattagc ttgaacacga gcagctgtag agggcatcat
   116221 cgaatctgga gtaatggtag ctaggatgat aaaatccagt tcctctccta ttattccagc
   116281 ttttgccatc agtttcttag caacctctgt agccaaatca ctggtagatt ctgttcttga
   116341 aatatgcctt tgtcgtattc ccgttcgact tgaaatccac tcatcattgg tatccataat
   116401 ctgagccaag tcgtgatttg taaccacttg ctctggaaca taatgagcaa cctggcttat
   116461 ttttgaaaaa gccattattt caaatcctcc aaaaattggt aaagattagt caaaccttta
   116521 cccatgacag caatttcttc ctcgctcatg ccatcaataa ttttttctac catggccttg
   116581 tggaagcgtt tatgcagtct atgaatcaag cgacccttct ttgtcaaatg cagatgcacc
   116641 acacgacgat cctgttctga ccgaactcgc tcaatgtagc ccttacgctc taaattgttc
   116701 aaacttgtcg taacagttcc aagagttacc atcaactctt ttgacacttg acttggagtc
   116761 acgtctggag ccttaccgat aacatcaatc gtatgcattt ctttgatgga gatatcctta
   116821 aaacgactac ctctcaagtt cacttcctca atcacaagga cattgttaaa tatagatgtt
   116881 aaatattcat tgattcgttg gtagtccatt tttcatatcc ctccttcttc aaaaaacttt
   116941 tacaatcaaa acatttgaca aaaagaatta tatcaaaatt caaagaatga tgcaagtatt
   117001 ttttattttc ctgtaaattt aggtcttctt ctctccgaat gagct
//
LOCUS       DAVDHZ010000003        91316 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000003 DAVDHZ010000000
VERSION     DAVDHZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 91316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.003"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            122..523
                     /locus_tag="VUR46_000231"
     CDS             122..523
                     /locus_tag="VUR46_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET5455733.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            523..801
                     /locus_tag="VUR46_000232"
     CDS             523..801
                     /locus_tag="VUR46_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET5455734.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKEEGKISLGK"
     gene            791..1564
                     /locus_tag="VUR46_000233"
     CDS             791..1564
                     /locus_tag="VUR46_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET5455735.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            1565..2869
                     /locus_tag="VUR46_000234"
     CDS             1565..2869
                     /locus_tag="VUR46_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET5455736.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            3443..4321
                     /gene="pstS"
                     /locus_tag="VUR46_000235"
     CDS             3443..4321
                     /gene="pstS"
                     /locus_tag="VUR46_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET5455737.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTMLEGRQ"
     gene            4321..5238
                     /gene="pstC"
                     /locus_tag="VUR46_000236"
     CDS             4321..5238
                     /gene="pstC"
                     /locus_tag="VUR46_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET5455738.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            5228..6112
                     /gene="pstA"
                     /locus_tag="VUR46_000237"
     CDS             5228..6112
                     /gene="pstA"
                     /locus_tag="VUR46_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET5455739.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            6123..6926
                     /gene="pstB"
                     /locus_tag="VUR46_000238"
     CDS             6123..6926
                     /gene="pstB"
                     /locus_tag="VUR46_000238"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5455740.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            6939..7697
                     /gene="pstB"
                     /locus_tag="VUR46_000239"
     CDS             6939..7697
                     /gene="pstB"
                     /locus_tag="VUR46_000239"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5455741.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            7709..8362
                     /gene="phoU"
                     /locus_tag="VUR46_000240"
     CDS             7709..8362
                     /gene="phoU"
                     /locus_tag="VUR46_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET5455742.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            8519..9334
                     /locus_tag="VUR46_000241"
     CDS             8519..9334
                     /locus_tag="VUR46_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET5455743.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     CLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(9354..10625)
                     /locus_tag="VUR46_000242"
     CDS             complement(9354..10625)
                     /locus_tag="VUR46_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET5455744.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKTNQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            10767..11498
                     /gene="budA"
                     /locus_tag="VUR46_000243"
     CDS             10767..11498
                     /gene="budA"
                     /locus_tag="VUR46_000243"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET5455745.1"
                     /translation="MDKNVQEPAKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGTGEQPEIVEVSPDTLIPYAAVVPHQAEVIFRQRFEMTD
                     KELEERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     GGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            11508..12260
                     /locus_tag="VUR46_000244"
     CDS             11508..12260
                     /locus_tag="VUR46_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET5455746.1"
                     /translation="MTIHIIIIMLLLLVFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLVYIIYGLAMAAFFEETARLVFFKCLEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            12372..13277
                     /gene="murB"
                     /locus_tag="VUR46_000245"
     CDS             12372..13277
                     /gene="murB"
                     /locus_tag="VUR46_000245"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET5455747.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSSITLEREVRILGESK"
     gene            13437..14594
                     /locus_tag="VUR46_000246"
     CDS             13437..14594
                     /locus_tag="VUR46_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455748.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDILLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILSGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            14575..15381
                     /locus_tag="VUR46_000247"
     CDS             14575..15381
                     /locus_tag="VUR46_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5455749.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGHRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            15378..16151
                     /locus_tag="VUR46_000248"
     CDS             15378..16151
                     /locus_tag="VUR46_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5455750.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLIVTQTFFLAFLSAFIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTKLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            16148..17218
                     /locus_tag="VUR46_000249"
     CDS             16148..17218
                     /locus_tag="VUR46_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5455751.1"
                     /translation="MKKLYSFLAGIVAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLEQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKLEGLENIGLEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNAAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDA
                     AYAFINFMLKPENALKNAEYVGYSTPNLPAKELLPEEKKEDKTFYPDAETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            17479..17718
                     /locus_tag="VUR46_000250"
     CDS             17479..17718
                     /locus_tag="VUR46_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455752.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            17993..18478
                     /locus_tag="VUR46_000251"
     CDS             17993..18478
                     /locus_tag="VUR46_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET5455753.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            18500..21118
                     /gene="alaS"
                     /locus_tag="VUR46_000252"
     CDS             18500..21118
                     /gene="alaS"
                     /locus_tag="VUR46_000252"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET5455754.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGSSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETPFYAEMGGQVA
                     DHGQILNASGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDTNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIVDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(21208..22662)
                     /locus_tag="VUR46_000253"
     CDS             complement(21208..22662)
                     /locus_tag="VUR46_000253"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET5455755.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSRIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFDASRAGSNYNLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEVLDRLLTIR
                     KDLAYGEQTDYFDDANCIGWVRSGAENQSPIAVLISNDQENSKSMFIGQEWAKQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSAASVSVWATNTI"
     gene            22841..23590
                     /locus_tag="VUR46_000254"
     CDS             22841..23590
                     /locus_tag="VUR46_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455756.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            23571..25205
                     /locus_tag="VUR46_000255"
     CDS             23571..25205
                     /locus_tag="VUR46_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455757.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFVLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTIKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            25892..27055
                     /locus_tag="VUR46_000256"
     CDS             25892..27055
                     /locus_tag="VUR46_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET5455758.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASELENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSTYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVVAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            27052..27729
                     /locus_tag="VUR46_000257"
     CDS             27052..27729
                     /locus_tag="VUR46_000257"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET5455759.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLGFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAAMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTMSMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            27719..28573
                     /locus_tag="VUR46_000258"
     CDS             27719..28573
                     /locus_tag="VUR46_000258"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET5455760.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGTYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            28592..29659
                     /locus_tag="VUR46_000259"
     CDS             28592..29659
                     /locus_tag="VUR46_000259"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET5455761.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            29669..30835
                     /gene="aroC"
                     /locus_tag="VUR46_000260"
     CDS             29669..30835
                     /gene="aroC"
                     /locus_tag="VUR46_000260"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET5455762.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQERGQEIKDYIDKIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            30845..31948
                     /locus_tag="VUR46_000261"
     CDS             30845..31948
                     /locus_tag="VUR46_000261"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET5455763.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADIIILSLPIKQTISFIKELANLDLKEGVIISDAGSTKSA
                     IVDAAENYLAGKPVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSPDTLEE
                     MKELLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNRETILERIEDFKERLDEVGQAISKGDEEQIWNFFN
                     QAREQRQAMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVVK"
     gene            31959..32297
                     /locus_tag="VUR46_000262"
     CDS             31959..32297
                     /locus_tag="VUR46_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET5455764.1"
                     /translation="MSNIYDSANELSRGLRELPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQDKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            32389..33672
                     /gene="aroA"
                     /locus_tag="VUR46_000263"
     CDS             32389..33672
                     /gene="aroA"
                     /locus_tag="VUR46_000263"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET5455765.1"
                     /translation="MKLKTNISHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVVTIQGVGMDGLKAPQNALDMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTIPLKKMGVSISGQTERDLPPLHLKGTKKLAPIQY
                     ELPIASAQVKSALMFAALQAQGESVIIEKECTRNHTEDMLQQFGAHLSVDGKKITVQG
                     LQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EVTEIDLVAKSATLTVESSDLQGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTVDGMIVKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVSDGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            33665..34141
                     /locus_tag="VUR46_000264"
     CDS             33665..34141
                     /locus_tag="VUR46_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET5455766.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGISIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIATDKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            34138..34986
                     /gene="pheA"
                     /locus_tag="VUR46_000265"
     CDS             34138..34986
                     /gene="pheA"
                     /locus_tag="VUR46_000265"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET5455767.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQTVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAGKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            34983..36257
                     /gene="psr"
                     /locus_tag="VUR46_000266"
     CDS             34983..36257
                     /gene="psr"
                     /locus_tag="VUR46_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET5455768.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTIDARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFGLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            36536..37381
                     /locus_tag="VUR46_000267"
     CDS             36536..37381
                     /locus_tag="VUR46_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5455769.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLICYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTVFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            37371..38474
                     /locus_tag="VUR46_000268"
     CDS             37371..38474
                     /locus_tag="VUR46_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET5455770.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTINS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            38476..39462
                     /locus_tag="VUR46_000269"
     CDS             38476..39462
                     /locus_tag="VUR46_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5455771.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQRQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            39478..40947
                     /locus_tag="VUR46_000270"
     CDS             39478..40947
                     /locus_tag="VUR46_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET5455772.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFVARKKIKVANIGSSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNIQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVMIFVAKILTKENQYLLNKGEKNHV"
     gene            40940..41974
                     /locus_tag="VUR46_000271"
     CDS             40940..41974
                     /locus_tag="VUR46_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET5455773.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            42174..42911
                     /gene="mecA"
                     /locus_tag="VUR46_000272"
     CDS             42174..42911
                     /gene="mecA"
                     /locus_tag="VUR46_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET5455774.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            43062..44348
                     /locus_tag="VUR46_000273"
     CDS             43062..44348
                     /locus_tag="VUR46_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET5455775.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHSAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILATDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            44350..45219
                     /locus_tag="VUR46_000274"
     CDS             44350..45219
                     /locus_tag="VUR46_000274"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET5455776.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            45295..45372
                     /locus_tag="VUR46_000275"
                     /pseudo
     CDS             45295..45372
                     /locus_tag="VUR46_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            45514..46452
                     /gene="msrB"
                     /locus_tag="VUR46_000276"
     CDS             45514..46452
                     /gene="msrB"
                     /locus_tag="VUR46_000276"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET5455777.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            46512..48236
                     /locus_tag="VUR46_000277"
     CDS             46512..48236
                     /locus_tag="VUR46_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455778.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRNRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELAFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            48238..49986
                     /locus_tag="VUR46_000278"
     CDS             48238..49986
                     /locus_tag="VUR46_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5455779.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRGRII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            50288..51547
                     /locus_tag="VUR46_000279"
     CDS             50288..51547
                     /locus_tag="VUR46_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET5455780.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKALGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    51623..51758
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            51797..52297
                     /locus_tag="VUR46_000280"
     CDS             51797..52297
                     /locus_tag="VUR46_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET5455781.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            52373..52741
                     /gene="rplL"
                     /locus_tag="VUR46_000281"
     CDS             52373..52741
                     /gene="rplL"
                     /locus_tag="VUR46_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET5455782.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DATDAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            52943..53116
                     /locus_tag="VUR46_000282"
     CDS             52943..53116
                     /locus_tag="VUR46_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455783.1"
                     /translation="MTKELQSSRHIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            53113..53892
                     /locus_tag="VUR46_000283"
     CDS             53113..53892
                     /locus_tag="VUR46_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET5455784.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQDENDTAPVSHLAPSETEVSETKYSE
                     TDSLFIEDEEERNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            53991..55349
                     /gene="dcm"
                     /locus_tag="VUR46_000284"
     CDS             53991..55349
                     /gene="dcm"
                     /locus_tag="VUR46_000284"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET5455785.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGTRLLFPFRREGQATNSETLKALGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLEKRQNGRRFKDNQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYQVAGILIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     IK"
     gene            55333..55782
                     /locus_tag="VUR46_000285"
     CDS             55333..55782
                     /locus_tag="VUR46_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455786.1"
                     /translation="MKALNRESILDCDELETELHDAEIKQLDEQIFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFVDDNQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKQPINFANLLDSLIVSEYQMEPNLWEVSHD"
     gene            55775..56155
                     /locus_tag="VUR46_000286"
     CDS             55775..56155
                     /locus_tag="VUR46_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455787.1"
                     /translation="MIDLYLSKNNHRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            56168..56401
                     /locus_tag="VUR46_000287"
     CDS             56168..56401
                     /locus_tag="VUR46_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5455788.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            56404..56991
                     /locus_tag="VUR46_000288"
     CDS             56404..56991
                     /locus_tag="VUR46_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5455789.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYGASLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFISLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGLVRYKSDLWGSMGLHLVWNLSVYVLFLL"
     gene            57368..57682
                     /locus_tag="VUR46_000289"
     CDS             57368..57682
                     /locus_tag="VUR46_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET5455790.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            57698..58084
                     /locus_tag="VUR46_000290"
     CDS             57698..58084
                     /locus_tag="VUR46_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET5455791.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            58113..59495
                     /locus_tag="VUR46_000291"
     CDS             58113..59495
                     /locus_tag="VUR46_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET5455792.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLHL
                     EKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEYD
                     KLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKE
                     DLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKE
                     NTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGM
                     MFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQA
                     TCEAEVAGVD"
     gene            59498..59650
                     /locus_tag="VUR46_000292"
     CDS             59498..59650
                     /locus_tag="VUR46_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET5455793.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            59673..61088
                     /locus_tag="VUR46_000293"
                     /pseudo
     CDS             59673..61088
                     /locus_tag="VUR46_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            61271..62065
                     /locus_tag="VUR46_000294"
                     /note="aph(3')-IIIa"
     CDS             61271..62065
                     /locus_tag="VUR46_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HET5455794.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            62341..62913
                     /locus_tag="VUR46_000295"
     CDS             62341..62913
                     /locus_tag="VUR46_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HET5455795.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVILIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            63242..63483
                     /locus_tag="VUR46_000296"
                     /pseudo
     CDS             63242..63483
                     /locus_tag="VUR46_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            63532..63615
                     /locus_tag="VUR46_000297"
     CDS             63532..63615
                     /locus_tag="VUR46_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HET5455796.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            63740..64477
                     /gene="erm(B)"
                     /locus_tag="VUR46_000298"
     CDS             63740..64477
                     /gene="erm(B)"
                     /locus_tag="VUR46_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HET5455797.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(64734..65981)
                     /locus_tag="VUR46_000299"
     CDS             complement(64734..65981)
                     /locus_tag="VUR46_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5455798.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            66161..66382
                     /locus_tag="VUR46_000300"
     CDS             66161..66382
                     /locus_tag="VUR46_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455799.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            66499..66996
                     /locus_tag="VUR46_000301"
     CDS             66499..66996
                     /locus_tag="VUR46_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET5455800.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            66971..67477
                     /locus_tag="VUR46_000302"
     CDS             66971..67477
                     /locus_tag="VUR46_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET5455801.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            67461..69908
                     /locus_tag="VUR46_000303"
     CDS             67461..69908
                     /locus_tag="VUR46_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5455802.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            69911..72088
                     /locus_tag="VUR46_000304"
     CDS             69911..72088
                     /locus_tag="VUR46_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET5455803.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            72085..73086
                     /locus_tag="VUR46_000305"
     CDS             72085..73086
                     /locus_tag="VUR46_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET5455804.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            73083..74018
                     /locus_tag="VUR46_000306"
     CDS             73083..74018
                     /locus_tag="VUR46_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET5455805.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            74263..74379
                     /locus_tag="VUR46_000307"
     CDS             74263..74379
                     /locus_tag="VUR46_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET5455806.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            74395..76314
                     /gene="tet(M)"
                     /locus_tag="VUR46_000308"
     CDS             74395..76314
                     /gene="tet(M)"
                     /locus_tag="VUR46_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET5455807.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            76433..76600
                     /locus_tag="VUR46_000309"
     CDS             76433..76600
                     /locus_tag="VUR46_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET5455808.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(76660..77013)
                     /locus_tag="VUR46_000310"
     CDS             complement(76660..77013)
                     /locus_tag="VUR46_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5455809.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            77518..77940
                     /locus_tag="VUR46_000311"
     CDS             77518..77940
                     /locus_tag="VUR46_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET5455810.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            77937..78167
                     /locus_tag="VUR46_000312"
     CDS             77937..78167
                     /locus_tag="VUR46_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5455811.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            78628..78831
                     /locus_tag="VUR46_000313"
     CDS             78628..78831
                     /locus_tag="VUR46_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET5455812.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            78913..80130
                     /locus_tag="VUR46_000314"
     CDS             78913..80130
                     /locus_tag="VUR46_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5455813.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            80400..80990
                     /locus_tag="VUR46_000315"
     CDS             80400..80990
                     /locus_tag="VUR46_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET5455814.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVAEGKIDA
                     EEKGLYRLPDIYLDEWFVLQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEVERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNKIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            80990..81826
                     /locus_tag="VUR46_000316"
     CDS             80990..81826
                     /locus_tag="VUR46_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET5455815.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIHIFEEILCSNTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AEKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQIIREIMQQ
                     IF"
     gene            82109..82408
                     /locus_tag="VUR46_000317"
     CDS             82109..82408
                     /locus_tag="VUR46_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455816.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            82398..82886
                     /locus_tag="VUR46_000318"
     CDS             82398..82886
                     /locus_tag="VUR46_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455817.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            82886..84763
                     /locus_tag="VUR46_000319"
     CDS             82886..84763
                     /locus_tag="VUR46_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET5455818.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSL
                     K"
     gene            84784..85026
                     /locus_tag="VUR46_000320"
     CDS             84784..85026
                     /locus_tag="VUR46_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455819.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            85043..85897
                     /locus_tag="VUR46_000321"
     CDS             85043..85897
                     /locus_tag="VUR46_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET5455820.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            85951..86310
                     /locus_tag="VUR46_000322"
     CDS             85951..86310
                     /locus_tag="VUR46_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET5455821.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            86303..88618
                     /locus_tag="VUR46_000323"
                     /pseudo
     CDS             86303..88618
                     /locus_tag="VUR46_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241830.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            88630..>91316
                     /locus_tag="VUR46_000324"
     CDS             88630..>91316
                     /locus_tag="VUR46_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5455822.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSFLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQESKQKSNFFFQGKSLEELKAKKE
                     VKAAKENLKSTKQAYKYKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     FRKLKKQGLSSVQNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELQKPV
                     HLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGQSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDAVVSL
                     DGDNIILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYDFLKSQGVSPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTSDGSTRYTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPADYGHVAFV"
BASE COUNT        27996 a        16510 c        19962 g        26848 t
ORIGIN      
        1 aatcgttcgc aaacagccta tttttcttga aaaaataggc tttttttcta aaaatcccta
       61 gtcaagcgcc ttattttttt gtataataga agtagcaaag tatagataag aagagaaaag
      121 catgattaca ctatttctat caccgagctg tacatcatgt cgtaaggcta aggcctggtt
      181 agaaaaacat aaggttccct ttgtggaaca caatattatg accagtcctt taacaagaaa
      241 agaattgcaa cacatccttt ccttgaccga aaatggtact gatgacatca tttcaactcg
      301 ttcaaaaatt tttcaaaaat tgaatattga tgtagagagt atttcggtat cggaattgct
      361 tcatttgatt gagcagtatc ctagtctttt gcgtcgtcca attattattg atgccaagcg
      421 tatgcaaatc ggttttaatg aagatgagat tcgtgctttt ctccctcgta gttatcgtaa
      481 gcaagaacta aaagaagcaa gaatgagagc tggtattagt taatgaacaa acagtatagt
      541 tacccactag atttgtcgtg gagcactgaa gaacttgctt cagtgctttc tttttttaat
      601 gatgttgaag ctgcctatga aggcaaagta gaggctaaaa agttactgga ctcctataag
      661 ggattcaaag cggtcgtgcc aagcaagagc gaagagaaac gtttgggacg agaatttgaa
      721 acggttagtg gctattcact ttaccgagca gttcaggctg ccaaagaaaa agaggaagga
      781 aagatttctc ttggaaagta aatttgaatt tgctaaagag cttgttaaga aagcaggtca
      841 gtacattctt gaccatatgc aggaagactt gcgtgttgaa accaagtcct ctccaacaga
      901 tttggtgacc agactggaca aagaagttca ggaactcttg gttggtgaga ttttgtcccg
      961 ttatcctgag gataagattt gtgctgaaga aggttgtctg cgagcctcgg ttcaagaggg
     1021 caaggtttgg gtcattgatc ccattgatgg taccaataat tttgtagccc agcaggaaga
     1081 ttttgctgtt atgatggctt attttgaaaa tggtcaggga cagtttggtc tgatttatga
     1141 tgtggtcaaa ggggattgtt accacggtgg tggggaattt ccagtttgtc taaatgatag
     1201 gcccctagct ccttttaaaa ctaaaccact tggagatttt ctcattgcag ggaatagtgg
     1261 tatgctggaa accaatgaat gggggctggc tgatttgagc cgagcggttc ttggtgttcg
     1321 tgtctatgga agtgcggcca ttagttttgc caagattttg tcagggcgtt tgttgaccta
     1381 tctcacttat ctgcaaccat gggattatgc cgcagctagt attttagggg aaagtctggg
     1441 ctatcgggtt gtgacccttt ttggtgaagc tcctgatttt caaaccagac agcctgtcat
     1501 gatggtgcct cttgagatgc aggaggaaat tcagtcctat atttacgaaa ggaaaagaac
     1561 ttaaatgcaa tttccagaag gatttgttga aaaatataaa gaaatactag gagatgaggc
     1621 aagagatttt cttgcctctt ttgaggagga agcggtttcg gcctttcggg tcaatccctt
     1681 aaaagaagag caactttcct tttctgatgc cattactcaa accccttggg gccactatgg
     1741 gaaggtttca gggaaatcgc ctgagcatgc tacaggttta gtttattcgc aagaacctgc
     1801 tgctcaaatg gtggctcaag tagcccaacc cagtcctggt atgaaggtct tggacttggc
     1861 tgctgcaccg gggggcaaat caactcaact ggcagcctat ctagcagggg aggggctact
     1921 tgtttccaat gaaatttcaa gcaaacgggc taagattttg gttgaaaaca tggagcgttt
     1981 tggagcgaca aatgtcgtgg tgaccaatga atctgccgac cgcttggtca aggtctttaa
     2041 aggctatttt gacttaatcg ttcttgatgc cccttgctct ggtgaaggaa tgtttcgtaa
     2101 gcagcctgat gctatggact attggagctt agattatccg agtcaatgtg ctagcttgca
     2161 aagagaaatt ctggaggatg cagtgaccat gttagctgaa ggtggtcgtc tggtttattc
     2221 gacctgtacc tgggcacccg aggaaaacga agagattgtc aattggttgc tggaagagta
     2281 tgattttgac ttgttgccag tagagcatat caatggaatg gtagctggta ttgacctgcc
     2341 agaaacggct cggatgtacc ctcatcagtt taagggagag ggtcagtttg ttgcccatct
     2401 acagtttaag ggtaacaatc cagctcctaa atttaaggca agtaagagta acctcagccg
     2461 tgaacaagtt gccttgtggc aggaatttgc ccaaaaccat ttgaaggtca atctaccggg
     2521 tatcttgcag acttttggag accagcttta tctcttgcca gaacttttgc cagatttagg
     2581 gaagctcaag attgctcgca atggactgca tctgggcact tttaagaaga aacgctttga
     2641 gcccagtttc gctcttggtt tagccttgaa accgagtcag gtcgaacagt cggttgaaat
     2701 tggccaagaa gcgtttgtca agtatgcggc tggagaaacc gttcagctgg cagaaagtct
     2761 gccaaatggt tggtaccaag ttttggttaa aggcaatggc ttgggctttg caaaggttac
     2821 tggaaatgtt ttgaaaaatt attttccaaa aggcctcaga ttcaaatgaa aatgctagtc
     2881 aaatatctta ttctatgtta tagtgaaagt atggattttt ttagtaggat gattcttgat
     2941 atcttgattg ccatcacatg tagttttact actcgatgaa aatcaaagag caaactagga
     3001 agctagccat agatagctca aaacactggt ttgaagagat tttcaaagag tacaagaagt
     3061 ttagttatta gcgttcttac cgcttgtaaa ctagatttct cataaaatag aatcttttcc
     3121 ttttagttgt aaactagtct gggagagtag agaggtttga gatacctttc tagcttttgg
     3181 attatcatct gaggagagta atttcccttg cattaaaaag gggaaaaaga gacacgaaat
     3241 gactataatg ggtgacaatg ggggaaggga tagacaagag attttatcca catatgaaaa
     3301 aaggaggtta ggaaagagta atatagccta tattatataa ataatcaatt gcgcagaaat
     3361 ttggtaagaa ttcatgcgtc aactcataaa gaactactta aaaaattcac agtattcata
     3421 attattttcg aggagaaaaa cagtgaaaaa aagaaaaaag cttgctctgt ctcttatcgc
     3481 tttttggctg acggcttgtt tagtaggctg tgctagctgg attgatcgtg gagaatccat
     3541 aacggctgtt ggctcaactg ccttgcaacc cttggttgaa gtagcggcag atgaatttgg
     3601 cacgatccat gttggaaaaa cggtcaatgt ccaaggggga ggttctggta caggcttgtc
     3661 ccaggttcag tctggggcag ttgatatagg aaactcagat gtatttgctg aggaaaaaga
     3721 cggaattgat gcttctgctc ttgttgacca caaggtcgcg gtagctggct tggctctgat
     3781 tgtcaataag gaggttgatg ttgataacct aacgacagag caacttcgtc aaatcttcat
     3841 aggtgaggta accaattgga aagaggttgg tggtaaggac ttacccatct ctgttatcaa
     3901 tcgggcagcc ggctctggct ctcgtgctac ctttgatact gtcattatgg aaggtcagtc
     3961 tgccatgcaa agtcaggagc aggattcaaa tggagcggta aaatcaatcg tatcaaaaag
     4021 tccaggagct atctcttatt tatctcttac ctatatagat gattcggtca aaagcatgaa
     4081 gttgaatggc tatgacttaa gtccagaaaa tataagtagc aataattggc ccttgtggtc
     4141 ttatgagcat atgtatacat tggggcagcc caatgagttg gctgcagaat ttctcaattt
     4201 tgttctctcg gatgagaccc aagaagggat tgtcaaagga ttgaagtata ttccgattaa
     4261 ggaaatgaag gttgaaaaag atgctgccgg aactgtgaca atgttggaag ggagacaata
     4321 atgaatcaag aagaattagc taagaaaatg ttgcttccat caaagaattc tcgtctggag
     4381 aaattaggaa aaggtttgac ctttgcctgt ctttctttga tagtcatcct tgtggccatg
     4441 attttggttt tcgtagcgca aaaaggcttg tcgaccttct ttgtcaatgg tgtgaatatc
     4501 tttgactttc ttttgggagg aacttggaat ccttctagta aagaatttgg tgcccttcct
     4561 atgattttgg gttcctttat cgttaccatt ctctcagccc ttatcgcaac accctttgct
     4621 attggtgcag cagtttttat gaccgaagta tcaccaaaag gggcgaagat tttgcaacca
     4681 gctattgaac tcctggttgg gattccttca gtagtgtacg gatttattgg cttgcaagtc
     4741 gtcgttccct ttgttcgcag tgtctttggt gggactggtt ttgggatttt gtcagggatt
     4801 tccgtcctct ttgtcatgat tttgccgacc gtaaccttta tgacaacgga tagcttgcgt
     4861 gcggttcctc gttattatcg tgaggccagt ttcgctatgg gagctactcg ctggcagact
     4921 atctggcgtg tgatcttgaa ggcggcccgt tctggtattt tcactgcagt ggtctttggg
     4981 atggcgcgtg cctttggtga ggctctagct atccagatgg ttgtcggaaa ctcagctgtt
     5041 atcccaactt ccttgaccac accagctgca actttaactt ctatattaac tatgggaatt
     5101 gggaacactg tcatgggaac tgtaaataat aatgttctct ggtcactggc cttggtactg
     5161 ctcttgatga gtttagtttt taacagtgtg attaaattga ttacgaaaga aagaggaaag
     5221 aaaaattatg cgcgctaaga aattagataa acttgcaaca gctgtcctct atacgattgc
     5281 tagcatcatt gtgacaatct tggcttcctt gattctctat atcttggttc ggggcttgcc
     5341 ccatatctct tggtctttct tgactggaag gtcttctgct tttcaagcag gtggtgggat
     5401 tggcattcag ctttacaatt cctttttcct attggtcatt accttgatta tttctgtacc
     5461 tctttctatg ggagctggga tttacttggc tgaatatgct aaaaaaggtc ctgttaccaa
     5521 ctttgtgcgg acttgtattg aaatcttgtc ctctttacca tcagtggtgg tgggtctctt
     5581 tggttacttg atctttgtag tccagtttga gtatggattt tcaatcattt caggtgcctt
     5641 ggccttgaca gtctttaact tgcctcagat gacgcgtaat gtagaggata gtttgaaaca
     5701 cgttcaccat acccaacgtg aggctggtct ggctcttggg atttctcgct gggagacagt
     5761 ggttcatgtt gttattccag aagcgcttcc aggtattgta acgggtgtcg tcttggcatc
     5821 tggtcgtatc tttggcgaag ctgcagctct gatctataca gcagggcaat cggcgccagc
     5881 tcttgactgg tctaactgga atatcctcag tgtgactagc cccatctcta tcttccgtca
     5941 agcagaaacc ttggctgtcc atatctggaa agtcaatagt gaaggcacta ttccagatgg
     6001 aacaattgta tcagcaggtt ctgccgctgt gctcctgatc tttatcctga tttttaactt
     6061 tggagctcgt aagttcggaa gctatctaca caagaaatta accgctgcct aaaggagaag
     6121 ccatgtcaac atataactgg gatgagaagc atatccttac ctttcctgaa gaaaaagtag
     6181 ccctttctac taaggatgtc catgtttact atggtaaaaa tgaatccatt aaggggattg
     6241 atatgcaatt tgaaagaaat aaaattacag ctttgattgg tccgtcggga tcggggaaat
     6301 ctacctactt acgcagtctc aatcgcatga atgatactat tgatattgct aaagtaactg
     6361 ggcagattct ctatcgtgga attgatgtca accgtccaga aatcaacgtt tatgaaatgc
     6421 gtaaacacat tggaatggtt tttcaacgcc ccaatccatt tgctaagtca atttaccgta
     6481 atattacctt tgcgcatgaa cgtgctggag ttaaggataa gcaagtccta gatgaaatcg
     6541 tagaaacctc ccttcgtcag gctgccctct gggatcaggt taaagacgat ctccacaagt
     6601 cagccttgac cttatcaggt ggtcagcaac aacgtctctg tatcgctcgt gccatctctg
     6661 ttaagccaga tatcctctta atggatgagc cagcctcagc cttggatccg attgcgacca
     6721 tgcaactaga agagaccatg tttgagctca agaaaaactt taccatcatc attgtaacgc
     6781 ataatatgca gcaggctgct cgtgcaagtg actatacagg cttcttttac ttgggtgatt
     6841 tgattgagta tgacaagact gcaactattt tccaaaatgc caagctacag tccaccaatg
     6901 actatgtatc tggtcacttt ggttagaaag gaaaccgtat gacagatgcg attttacagg
     6961 tatcagacct gtccgtttat tataataaaa agaaggcttt gaatagtgtt tccctatctt
     7021 tccaacctaa ggaaattaca gccttgattg gtccatctgg atcagggaag tcaaccctcc
     7081 tcaagtctct taaccgcatg ggagatctca atccagaggt gaccacaact ggatccgtgg
     7141 tgtacaatgg tcacaacatc tacagtccgc gtacagatac ggttgaatta cgtaaggaaa
     7201 tcggaatggt tttccaacaa cctaatcctt tccctatgac tatctatgag aatgttgtct
     7261 acgggcttcg tatcaatgga attaaggata agcaggttct ggatgaagcc gtagaaaaag
     7321 ccttgcaagg tgcctctatc tgggatgagg tcaaggatcg tctatatgat tcagctattg
     7381 gattgtcagg tggtcaacag cagcgtgtct gcgtggcccg tgtcttggca actagtccta
     7441 aaatcatcct cttggatgag ccaacttcgg ctttggatcc gatttcagct ggtaaaattg
     7501 aggaaacctt gtatggtcta aaagacaagt acaccatgct tctggtaacc cgttccatgc
     7561 agcaagcttc acgtatctct gataagacag gatttttcct agatggagat ttgattgaat
     7621 ttaatgatac caagcagatg ttccttgatc cccaacacaa ggaaacggaa gactatatta
     7681 caggaaaatt tggataagga gatgaaagat gttacgatct caatttgaag aagatttaga
     7741 gaaattacat aaccagttct acgctatggg acaagaagtg ctctcacaaa tcaatcgtac
     7801 ggtacgtgct tttgtcacgc atgaccgtga cctggcaaaa gaggtcatcg aagatgatgc
     7861 agaagtaaat gaatacgaag tgaaactgga aaagaaatca tttgaaatga tcgcactcca
     7921 acaaccagtc tctcaagatt tgcgtacagt cttgactgtc cttaaggctg tatcagatgt
     7981 ggagcgtatg ggggatcacg ctgtagccat tgcccaggca accatccgta tgaaggggga
     8041 agaacgcatc ccagctgtag aggaagaaat taaaaaaatg ggacgtgaag ttaaaagcgt
     8101 tgttgaagca gcacttgatc tttatcttaa tggttctgtt gacgacgcat accgggtggc
     8161 ctccatggat gagcaaatta accactattt tgaaactatc cgtgaccttg cgactgaaga
     8221 gattaagaaa aatccagaag ccattgttac gggtcgtgat tatttccaag ttatttccta
     8281 cttggagcgt atcggtgact atgctaaaaa tatctgtgaa tgggttgtct actttgaaac
     8341 aggtaagatt gtcgaactat aaaatagttt aattctgtat aaaaaggagc ttggaatcaa
     8401 ctgatggctc ctttttttga acaaaaaaat atttttgaga taaaaattta aaaaacactt
     8461 gacaagtaac ttggatatcg ttataattat acaaaattaa cagagaggtt gtttatttat
     8521 gaaatcaaaa aaatggatat ttgttttatg taattttctt gcaagtttct tcttagtagc
     8581 ttgccagtca ggttctaatg gttctcagtc agctgttgag gccattaagc aaaaggggaa
     8641 attagttgtg gcaaccagtc ctgactatgc accctttgaa tttcaatcat tggttgatgg
     8701 aaagaaccag gtagtcggtg cagacatcga catggctcag gctatcgctg atgaacttgg
     8761 ggttaagttg gaaatctcaa gcatgagttt tgacaatgtt ttgaccagtc ttcaaactgg
     8821 taaggctgac ctagcagttg caggaattag tgctactgac gagagaaaag aagtctttga
     8881 tttttcaatc ccatactatg aaaacaagat tagtttcttg gttcgtaagg ctgatgtgga
     8941 aaaatacaag gatttaacta gcctagaaag tgctaatatt gcagcccaaa aagggactgt
     9001 tccagaatca atggtcaagg aacaattgcc aaaagctcaa ttaacttccc taactaatat
     9061 gggtgaagca gtcaatgaat tgcaggctgg aaaagtagat gctgttcata tggatgaacc
     9121 tgttgcactt agttatgctg ctaaaaacgc tggcttagct gtcgcaactg tctgcttgaa
     9181 gatgaaggac ggcgacgcca atgccgttgc tcttagaaaa aatagtgatg atttgaaaga
     9241 agtggtagac aaggttatcc aaaaacttaa ggatgaagga acttaccaaa gctatcttga
     9301 aaaagcagca agtctaactg aagttgaaga ataagaaaaa gcagagttgg atgtcattcc
     9361 aattctgctt ttaaatagtt taaaacattt tccagattgt ctagggacac cttggcaaat
     9421 tgataaggac aggtgcttaa ataggcctct tcaaagaagt ccaagcccag ttgactgtgt
     9481 ttgagactgg cgattttagg atactgtctc aggtctagca ataaaccatc gtgtagggga
     9541 taatgaggga ggggacaagg tgttttagtt atcctttctt cgatttgttt ttggtaagat
     9601 tcatgattgg tcaagcgagc caaacgattt ttttcaaaca attgactgtc aatatagagt
     9661 gacagggcct tttgcataat gaggttgctg tcgtagtcta ggatattttt gtaggccaca
     9721 aatgcttctt tgatagcatt tggaagaatg agtgctgtaa tacgaagggc aggaaaaagg
     9781 ctggtcgaga aggacttgat ataaataaca tgctcctctg tatcaagata gtggaaggtt
     9841 tggcccttct tggagtccaa atcacccaga taatcgtcct ctacgatata gacatcatac
     9901 ttggcagcta agttaagaat agatcgtttg tcttgctcag aataggaatg tcccagagga
     9961 tagtgaaatc ggggaatggt gtagaaaaat ttaatttttc ctgttttgaa gtggccttcc
    10021 agctcctcca agtcaatccc atcaatgcct cgttcaatcg tttgatagtc cagcccctgt
    10081 gcaatcaaga ggcgattcat ccgatggtag gttggctgtt ccaccaagat ttccttggct
    10141 tggctaggaa aggatatttg agataggata aacaaggctt gctgggttcc agaagtcagt
    10201 actagttggt tagtcttgca gtagagagct tggtcaaaga ggagtttgtg aatggattgt
    10261 cttaggtctt ctaatccttc ttgattgtca tagtagttga agaggtagtt ttctcggcca
    10321 atcaaggttt cattgacaca gagtcggaaa tcgtcatagg cactggcatg ttcgtcggta
    10381 acctcgattt ctaggtcttg atgttgccct tgttctaata catagtagcc actctgaggc
    10441 ttggcataga ggtattgttc gtgccgtaat tccagcaggg ctcgttgaat ggtgtccttg
    10501 ctgcagtgaa agtcaaggct cagttgacgg atagaaggca ggcgactacc cgtcggaaat
    10561 cgtccagact cgataccatt tttcagatag gaaacgacct ctttgtactt gctttgtttc
    10621 ttcattccag acctcccttg attttgttac attgtaccct tttttttcct tcttggcaat
    10681 gtctagagcg tttctctcgt tcacatctag gggcaaatgt ggtatactta ggagtaacat
    10741 ttatagaata acagacaaga aagtgaatgg ataagaacgt gcaggaacca gcgaaattat
    10801 ttcaatacaa tactcttgga gccttgatgg ctggccttta tggtggtacc atgacagtgg
    10861 gagaattgct agagcatggt gaccttggtt tgggaacctt ggattctatt gatggggaat
    10921 tgattgtctt agatggcaag gcttatcagg caaaaggaac aggagaacag ccagaaattg
    10981 tggaagtgtc accagatacc cttattcctt atgcagcagt agtaccgcat caggcagagg
    11041 tcattttccg ccagcgcttt gagatgacag acaaggaatt ggaagaacga attgagtctt
    11101 attatgatgg ggaaaatctt ttccgttcta tcaagattcg gggagaattt tcacatatgc
    11161 atgtgcgtat gattcctaag tcaacacccg ataccaagtt tgctgatgtc gcaacccatc
    11221 aaccggaata tagtcgtgac aatgttgggg ggactattgt tggtttctgg acgcctgaga
    11281 ttttccatgg ggtcagtgtg gcaggctacc atctgcactt catatcagat gatttgacct
    11341 tcggtggaca tgtcatggat tttgtcatca aggaaggcat tatcgaggtg ggagcagttg
    11401 accagttgga ccaacgtttc ccagtccaag accgtcaata cttgtttgct aagttcaatg
    11461 ttgacgagat gaaaaaagat attgaaaagg cagaatagga gaagaaaatg accattcata
    11521 tcattattat catgttgctg ttgctagttt ttctgatagg aagcatttgg tttgccaaaa
    11581 agaaatacca gattaatcta gctgtcttgg gcttgggtgc agtcgctttc tttgtctctt
    11641 cgcagatttt ggaaaaactg gtgcatatct tgattttgca tcctcaaaaa gacggtagta
    11701 ttgccctctt gcaagatcat ccgcttgtct atattattta tggcctagcc atggcagcat
    11761 tttttgagga aacggctcgt cttgttttct tcaaatgctt ggagaaaaag agaagtttgg
    11821 aaaaggcaga cgccttggcc tatggacttg ggcatggtgg cttggagttg atttttctag
    11881 gccttactag tttactcaat ctttacattg ttctttcggc agttcaaact cagaatccac
    11941 aggttatgca attactgtct gaaaatatgt taaaaaccat tcagtcactt tcggtctggc
    12001 agatttattt gcttggtttt gagcgaatct tggcgcttgg tttccaatta cttttgacag
    12061 tttgggttta ccaagctgtt cgccagaaga aatggattta tctcctagca gcctatggct
    12121 tgcatgcctt ctttgatctg gcaccatctc tttcccaagt aggctggttg acaaatccag
    12181 tcttggttga agtgattcta gcactggagc tcgttctggt cgcctatgga accaaggaaa
    12241 tcttttgtaa aaaatcataa aaagggggga acctcttttt cttatgcaaa atccaaacaa
    12301 ggtattttta tggtcgtcaa atgtctctaa aaatggtata atggaatgaa ttttgtaaaa
    12361 ggaagagtga catgtctgta agagaaaaaa tgcttgaaat cttagaagga attgatatcc
    12421 gttttaagga acccttgcat agctatagtt atacaaaagt aggtggagag gctgattatt
    12481 tggtctttcc acgaaatcgt tttgagttgg ctcgcgttgt gaaatttgcc aaccaagaaa
    12541 atatcccttg gatggttctt ggtaatgcaa gcaatatcat tgttcgtgat ggtgggattc
    12601 gtggatttgt catcttgtgt gacaagctca ataacgtttc tgttgatggc tataccattg
    12661 aagcagaagc tggggctaac ttgattgaaa caactcgcat tgccctccgt catagtttga
    12721 ctggctttga gtttgcttgt ggtattccag gaagcgttgg cggtgctgtc tttatgaatg
    12781 cgggtgccta tggtggcgag attgctcaca tcttgcagtc ttgtaaggtc ttgaccaagg
    12841 atggagaaat cgaaaccctg tctgctaaag acttggcttt tggttaccgc cattcagcta
    12901 ttcaggagtc tggtgcagtt gtcttgtcag ttaaatttgc cctagcccca ggaacccatc
    12961 aggttatcaa gcaggaaatg gaccgcttga cgcacctacg tgaactcaag caacctttgg
    13021 aatacccatc ttgtggctcg gtctttaagc gtccagtcgg gcattttgca ggtcagttaa
    13081 tttcagaagc tggcttgaaa ggctatcgta tcggtggcgt agaagtgtca gaaaagcatg
    13141 caggatttat gatcaatgtc gcagatggaa cggccaaaga ctacgaggac ttgatccaat
    13201 cggttatcga aaaagttaag gaacactcaa gtattacgct tgaaagagaa gtccggatct
    13261 tgggtgaaag caagtaggaa gctgtatttg aaaagctgct gctatgtcat ggaaaggggg
    13321 tgaaagccta tcggtagcga agatgtatgc aggtggtttt actccctgca agaggtagtg
    13381 gggacctgac agagccccga tcggttaatc tatgaaaaag aaggaattta tgccaattga
    13441 aaaaaccaat tatcgaattc aaaaacgtct ctaaagtttt tgaagacagc aacaccaagg
    13501 ttctcaaaga catcaacttt gagttggaag aaggaaaatt ctacaccctt ctaggtgcat
    13561 ctggttcggg gaaatcaacc atcctaaaca ttattgcagg gttactggat gcgacgacag
    13621 gagatatttt gctggatggt gtccgtatca atgacatccc aaccaacaag cgagacgtcc
    13681 ataccgtttt ccaatcttat gccttgtttc cgcatatgaa tgtgtttgaa aatgttgcct
    13741 ttccacttcg cttgcgtaaa attgacaaga aagaaatcga gcaacgcgta gcggaagttc
    13801 tcaagatggt tcagttggaa gggtatgaaa aacgttccat ccgcaaactt tctggaggac
    13861 aacgtcagcg tgtggctatt gcccgtgcca tcatcaacca accccgtgtg gtcttgttgg
    13921 acgaacctct gtcagcgctg gacttaaaat tacgaacaga catgcagtac gaactgcgtg
    13981 aactgcaaca acgattggga atcacctttg tttttgttac tcatgatcag gaagaagcgc
    14041 tggccatgag tgactggatt ttcgttatga atgatggcga gattgtccag tctggaacac
    14101 cagtagatat ctacgatgag ccaatcaatc actttgttgc cacctttatc ggcgagtcaa
    14161 atatcttgtc aggaaccatg attgaggact acttggtcga atttaacggc aaacgcttcg
    14221 aagcagtcga tggggggatg aagccaaatg aacctgttga ggtcgttatt cgtccagagg
    14281 acttgcgcat tacccttcct gaagaaggca agctccaagt taaggtggat acccagctct
    14341 tccgtggagt tcactatgaa attatcgcct atgacgagct tgggaatgaa tggatgatcc
    14401 actcaacccg taaggctatt gttggtgagg aaatcggtct ggactttgaa ccagaagaca
    14461 tccatatcat gcgtctcaac gaaacagaag aagagttcga tgctcgtatc gaagaatacg
    14521 tggaaatcga agagcaagaa gcaggtttga tcaatgcaat cgaggaggaa agagatgaag
    14581 aaaacaagct ctaaactctt tgtagtgccc tacatgcttt ggattgccct ctttgttctg
    14641 gcacccttgg tcttgatttt cggtcaatcc tttttcaaca tcgaaggcca gttcagttta
    14701 gaaaattaca aatcttactt tgcgtcacaa aacttgacct acctaaaaat gagtttcaac
    14761 tctgtactct atgcagggat tgtaaccttt gtgaccttgc ttatcagcta tccgacagcc
    14821 ctctttttga cccgtctcaa gcaccgtcaa ctctggctca tgctgattat cctgccaacc
    14881 tggatcaatt tgctccttaa agcctatgcc tttatcggga tttttggtca gaatggctct
    14941 attaatcaat tcttggaatt tatcggaatt ggttcgcaac agttgctctt taccgatttc
    15001 tcctttatct ttgtcgcaag ctacatcgag cttcccttta tgattttgcc gattttcaat
    15061 gtcttggacg atatggataa caatctcatc aatgccagct atgacctcgg tgcgaccaag
    15121 tgggagacct tccgtcatgt catcttccct ctatcgatga acggtgtgag aagtggggtt
    15181 caatccgtct ttatcccaag tttgagtctc ttcatgctga cccgtttgat tggtgggcac
    15241 cgcgttatca ccttggggac ggctattgaa cagaatttcc taaccaatga caactacggt
    15301 atgggttcaa ccatcggtgt aattctcatc ttgaccatgt tcatcaccat gtgggtgacc
    15361 aaggaaagga gagaacgatg aaaaaatttg ccaaccttta tctaggactg gtctttcttg
    15421 tcctctacct gccgattttt tatttgattg gctatgcctt taatgctggt gatgatatga
    15481 atagctttac aggttttagc tggactcact ttgaaaccat gtttggcgat ggtcgcctta
    15541 tgttaattgt gactcaaacc tttttcttgg cctttttatc agcctttatt gcgaccatta
    15601 tcgggacttt cggtgctatt tacatctacc agtctcgtaa gaaatatcaa gaagcctttc
    15661 tttcactcaa taatatcctc atggttgcgc ctgacgttat gattggtgcc agtttcttga
    15721 tcctctttac caaactcaag ttttcacttg gctttttgac cgttctatct agtcacgtgg
    15781 ccttctccat tcctatcgtg gtcttgatgg tcttgcctcg tctcaaggaa atgaatggcg
    15841 atatgattca tgcggcctat gaccttggtg ccagtcaatt tcagatgttc aaggaaatta
    15901 tgcttcctta cctgactcca tctatcattg ctggttattt catggccttc acctattcgc
    15961 tagatgactt tgctgtgacc ttctttgtaa cgggaaatgg cttttcaacc ctgtcagtcg
    16021 agatttactc tcgtgctcgt aaggggattt cgctagaaat caatgccctg tctgcccttg
    16081 tctttctctt tagtattatc ctagttgttg gatattactt tatctcacgt gagaaggagg
    16141 agcaagcatg aaaaaactct attcattttt agcaggaatt gtagccatta tcctcgtctt
    16201 gtggggaatt gcgactcatc tcgatagtaa aatcaatagt cgagatagtc aaaaactggt
    16261 tatctacaac tggggggact atatcgatcc agaactcttg gagcaattta cagaagaaac
    16321 aggcatccaa gtccagtatg agacctttga ctccaacgaa gccatgtata ccaagatcaa
    16381 gcagggtgga acgacctacg atattgccat tcctagtgaa tacatgatta acaagatgaa
    16441 ggacgaagac ctcttagtac cgcttgacta ttcaaaactt gaaggtcttg aaaatatcgg
    16501 attagagttc ctcaaccagt cctttgaccc aggaaataaa ttctctatcc cttacttctg
    16561 gggaaccctg ggaattgtct acaatgaaac tatggtagat gaagcgcctg agcactggga
    16621 tgacctctgg aagccagagt ataagaactc tattatgctc tttgatgggg cgcgtgaggt
    16681 gctgggacta ggacttaatt cccttggcta cagcctcaac tccaaggatc cacagcagtt
    16741 ggaagagaca gtagataagc tctataaatt gactccaaat atcaaggcta tcgttgccga
    16801 cgagatgaag ggctacatga ttcagaacaa tgctgccatc ggtgtgacct tctctgggga
    16861 agctagccaa atgctagaaa aaaatgaaaa tctacgctat gtggtaccga cagaagccag
    16921 caacctttgg tttgacaata tggtcattcc caaaacagtc aaaaaccaag atgcagccta
    16981 tgcctttatc aactttatgt tgaaacccga aaatgctctc aaaaatgcgg agtatgtcgg
    17041 ctattcaaca ccaaacctac cagctaagga attactccca gaggagaaaa aagaagacaa
    17101 gaccttctat cctgatgctg aaaccatgaa acacctagag gtttatgaga aatttgacca
    17161 taaatggaca ggaaaatata gcgacctctt cctacagttt aaaatgtatc ggaagtagga
    17221 gataaacgta agaagacgaa tcagtcaagc tggttcgttt ttaaggaata gaagtcagtt
    17281 tttagagccc tatctttttc tattctagtt gtttatttgc ttatttgctt atttgcttgc
    17341 ctagtagtat actaagccta tactcttcaa accatgtcag cgttgccttg ccgtactcaa
    17401 gtacagcttg aggctagctt cctagtttgc tttttgattt ttattgagta ttaaccttac
    17461 agaaagcggc aacaaataat gaaaatgtct acttttttca aaaaaagttt ctggccaacc
    17521 tttatgattg ttaaccaaac tgttatacta ttccatttaa aggatggctt ggatcgacaa
    17581 tacctaacaa ctgagtccat atattgggtg ataggcacct ttatatttgg aaatattcta
    17641 gtagctgtgt ttagtaatat gaaaatttgg gataaaaaga aaaatggcag taagaaaaaa
    17701 tatatcctga aaaagtaatc agagatgtag ggaattggtc taattcaacg gagatcattt
    17761 ccagttgacg caagcttaaa aaaacgttat aataagagag ttgagaattg attttcactt
    17821 gtcttagtcc agagaaatgg cggtgctgcg agccatctaa gctaggaagt catgctactc
    17881 aatcatacaa ttgcataaga acaagagaat gacaagttca ttgaatgaag gtggtaccgc
    17941 ggtttttcgc ccttcgtgat atgagcttgt cttttgattt ttggaggtgt tgatgaaaac
    18001 atttcttgtc aaacaaaagt ttcgtcttgg aggcgaacgc ttcgctatca aggatgacag
    18061 gggagaaatt gcctatcagg tggagggatc attttttaag attcctaaaa cctttaccat
    18121 ctatgatgcg gctggtgaac aagtcagtga gattagtaaa gaaatcttga ccttgcttcc
    18181 tcgttttgag attcagcttc gggatggctc gagttttgtc attcgtaaga agttgacctt
    18241 ctggcgagat aagtatgagt ttgataatct aggtcttcgt atcgagggca atatctggga
    18301 tttgaatttc aaattgctgg atgatcgcga tcagttgatt gcggaaatta agaaggaact
    18361 cttccatctg acctctacct ataccgtaac ggttcttgaa gacgcttatg cagacctagt
    18421 catttccctc tgtgtcgcga ttgactatgt ggaaatgctg gaaagccaat cacattaaac
    18481 aagtgaataa ggagacaata tgaaacaact atctagtgca caagtacgcc aaatgtggct
    18541 tgatttctgg gcgaccaaag gtcactcagt agaaccatca gtaagtttgg ttcctgtaaa
    18601 tgacccaact cttttgtgga tcaactctgg ggtagcaacc cttaagaaat actttgacgg
    18661 gaccattatc cctgaaaatc cacgtattac caatgcccaa aaggctatcc gtaccaacga
    18721 catcgaaaac gtagggaaga ctgcgcgtca ccataccatg tttgaaatgc tggggaactt
    18781 ctctatcggg gattacttcc gtgacgaagc tatcacttgg gcttatgagc ttttgacaag
    18841 ccctgaatgg tttgatttcc ctgctgaaaa actttacatg acctactatc cagacgataa
    18901 agattcttac aaccgctgga ttgaagtggg agtggatcca agtcacttga ttccaattga
    18961 ggacaacttc tgggaaatcg gtgcgggacc ttctggacca gatacagaaa tcttctttga
    19021 ccgtggggaa gcctttgacc cagaaaatat cggtcttcgc ctgcttgcag aagatattga
    19081 aaacgaccgt tatattgaaa tctggaacat cgttttgtca caatttaacg cagaccctgc
    19141 tgttcctcgt agcgaataca aggaattgcc acataagaac attgatacgg gcgctggttt
    19201 ggagcgtttg gtggctgtta tccaaggggc taagaccaac tttgaaacgg acctcttcat
    19261 gccgattatc cgtgaagtcg agaaattgtc tggtaaggtt tatgaccaag atggcgacaa
    19321 catgagcttc aaggttatcg cagaccacat tcgttctctt tcatttgcta tcggtgatgg
    19381 tgcccttcca ggaaatgaag gtcgtggtta tgttcttcgt cgtcttctcc gtcgtgcttc
    19441 tatgcatggt caaaaattgg gtatcaacga gcctttcctt tacaaattgg ttccaactgt
    19501 tggaaaaatc atggaaagct actacccaga agtgcttgag aaacgtgact ttattgagaa
    19561 aatcgttaag agcgaagaag aatcatttgc ccgtaccctt cactcaggtc aacactttgc
    19621 ccaaggcatt gtggcagact tgaaagaaaa aggtcaatct gtcattgctg gtcaagatgt
    19681 ctttaaactc tatgatacat acggattccc agttgaattg actgaagaaa ttgctgaaga
    19741 ggctggtatg actgtagacc gtgaaggttt tgaagcagcc atgaaagaac aacaagaacg
    19801 cgcgcgtgcg tcagctgtca agggtagctc aatgggtatg caaaatgaaa ctcttcaaaa
    19861 catcactgta gaaagtgtct tcaactacaa tgctagccaa ttgtcttcta aattggtagc
    19921 tatcgtggcg gacaatgcag aagtagaagc tgtatcagaa ggaactgcct cacttatctt
    19981 tgcggaaacg ccattctatg ctgaaatggg cggacaggta gctgaccatg gacaaatctt
    20041 gaatgcgtca ggtaaggtcg tggctactgt gaccaatgtt cagaaagctc caaacggaca
    20101 agctcttcat acagttgaag tccttgcacc gcttgccttg aaccaagaat ataccttggt
    20161 aattgataca aatcgtcgtc accgtgtcat gaaaaaccat actgcgactc acttgcttca
    20221 cgctgccctt cacaatatcc ttggaaatca cgcaacacaa gcaggatctc ttaacgaagt
    20281 tgaattcctt cgctttgact ttacgcattt ccaagcagta actgctgaag aattgcgtgc
    20341 gattgaacag caagtcaacg agaaaatctg ggaagctctt gaagtgaaga cagttgaaac
    20401 ggatattgac actgctaaag aaatgggagc tatggctctc tttggtgaga aatacggtaa
    20461 ggaagtccgt gttgttacta tcggtgacta ctctatcgag ctttgtggtg gtacccacgt
    20521 tggcaacact tctgaaattg gtcttttcaa gattgtcaaa gaagaaggga ttggatcagg
    20581 aactcgccgt atcttggcag tgactggtaa ggaagccttt gaagcttacc gtgaacaaga
    20641 agacgctctt aaagctgtcg cagcaacctt gaaagcacct caagtcaagg aagtacctca
    20701 caaggtagaa ggacttcaag aacaacttcg tcaacttcaa aaagaaaatg ctgaattgaa
    20761 agaaaaagcc gcagctgcag ccgcaggcga tatcttcaag gatgtgaagg aagtcaacgg
    20821 tcaccgttac attgctagcc aagtttctgt atcagatgca ggtgcccttc gtacttttgc
    20881 agataattgg aaacaaaaag actactctga tcttcttgtc ctagttgccg ctatcggtga
    20941 caaagtcaat gtccttgtag caagcaagac aaaagacctt catgcaggaa accttgtcaa
    21001 agaattggca ccaatcgtcg atggacgtgg tggtggaaaa ccagacatgg ccatggcagg
    21061 aggaagcaac caagctaaaa ttcaagaatt gttggatgca gtagcaggta aattgtaatc
    21121 gagtaaagat ctatccattt gggtaggtct ttttgtgaat gcaaaaaagc caaatccgat
    21181 tggacctggc ttgattatca ttagctatta gattgtattg gttgcccaga cacttaccga
    21241 agcagctgag actgggaatt gtccataacc ttcctcatca attgtaactt gaccttggtg
    21301 gtttccaagt aaatctacaa aggtttgttt agcccattct tggccgataa acattgactt
    21361 gctgttttct tggtcatttg aaatcaagac tgcgattggg gattgatttt cagcgcctga
    21421 acgtacccaa ccgatacagt tagcatcatc aaagtagtct gtttgctctc cataggccaa
    21481 atcttttcgg atggttagga ggcggtcaag gacttctttg aaatcttctt gagcatattg
    21541 ccctgaaatc ccatagtagt cgccgtaaaa gacacatgga agcccatctt ggcgtaatag
    21601 aatgagggca taggctgctg gtttgaacca ttcttcaaca gtagattcaa gagcttgtcc
    21661 tcgttgggta tcgtggttgt cgacaaaggt aacagccttg tcaggtttga gttcaaccag
    21721 gctatctgtg aaaatgccac gaaggttata gttggaacct gctcggctag catcaaagag
    21781 attctggtgg agacgaacat cgacaaggtc aaagtgttct tccgtttttt cgagatagtc
    21841 cagattggct tccttgtctg ggttccaaaa ttcaccaaaa acatagaaat cgtcaccgta
    21901 tttttccttc atatcgcgga tgaagttgcg cataaagaaa gagtcaatat gcttaacggc
    21961 atccaaacgg aaaccagcta caccagtcgt ttccatgaac caatcagccc agtcatagat
    22021 gttttggatg acttcaggat gtttaaagtc taggtcggca tacatgaggt agtcgtagtt
    22081 tccgttttcg ttatcgacca attcctcgtt agcccagccc ttgttgtccc cttggatcag
    22141 ataaatccta gatttactgc gtttggcatc gtagtctgta ccggtgaagt ggtaccaatg
    22201 ccagtggaag ccattatagg tatcttggcg accatcgaag gtaaaactag tccagccatt
    22261 gatggtgaag ggttctccaa gttcaactgt acggtctaca ggatcaactt cgataacctg
    22321 aaaggcttcc ctgttatcgg cagcagcctt gtggttgaga actacatcag ccatgggttg
    22381 aattccctgt gctttaaggg cttgaatggc ttgaagatag tcttctttga aaccatactt
    22441 ggtgcggaca gtcccttttt ggttgaactc tcctaagtca aataagtcat agaccccata
    22501 gccgacatct ttttcgttgg ttgccttgaa ggctggtggc atccagacgt gactgatccc
    22561 cagatgagct aggtgtggag cattttcagc cagacgcgtc cagtgttgac cgtcgtgggg
    22621 cagataccat tcaaagtatt gcatgagtgt ttgattttgc atgatgtttc ctcttacttg
    22681 tcaatcttgt tctttattct atcataaagt atctctcgga gcaaacgttt gcgtaagata
    22741 gaaggaaact attttaacta cttaaaataa agtattgatt tttttgtatc aaagtgctag
    22801 tatagcgatg tataatacag ataaagatag gagttgtccc atgattgaat ttcaaaatgt
    22861 tagtaagttg tatggtgata aagaggcctt gagtaatctc aatttgcaga ttgaaaatgg
    22921 agagattatg ggcttgattg gtcataatgg ggctggaaaa tcgaccacta taaaatccct
    22981 agtcagtatc atttcaccca gcagtggtcg tattttggta gacggtcagg agttatcgga
    23041 aaatcgcttg gctattaaac gaaagattgg ctacgtagca gactcgcctg acttattttt
    23101 acgcttaacg gccaatgaat tttgggaatt gatcgcctca tcctatgatc tgagtagatc
    23161 tgacttggag gctagtctag ctaggctatt gaacgttttt gattttgctg aaaatcgcta
    23221 tcaggttatt gaaactcttt ctcacggaat gcgtcagaaa gtctttgtca tcggagcact
    23281 cttgtctgat cccgatattt gggtcttgga tgaacccttg actggtttgg atccccaggc
    23341 tgcctttgat ttgaaacaga tgatgaagga acatgcacaa aaagggaaga cagtcttgtt
    23401 ttcaactcat gtcctagagg tggcagagca agtctgtgat cggattgcca ttttgaaaaa
    23461 ggggcatttg atttattgtg gtagtgtaga ggacttgaga aaagattacc cagaccagtc
    23521 tttggaaagt atctacctta gtcttgctgg tagaaaagag gaggttgcgg atgcgtctca
    23581 aggtcattaa aaaattagtt gatatcaata tcctttattc atctcaagaa gctaatctgg
    23641 ctaatctacg aaagaagcag gctaagaatc ctgggaaaaa agtaaatgtt tccgctagag
    23701 tcttaagttc ttacattttt tccagtctct tgatgatcat ctgttttagt aatatagcca
    23761 ttcattttcc ttttgaggaa atgcctgttt attttagttt catggttgct attttactag
    23821 tgattgcctt ttcaacttct ttaactgcat tttacaatgt tttttatgag agtaaggatt
    23881 tggcctccta tagtccctat gcttttaaag aatcagagat tataattgct aaaggactgt
    23941 ctgtcctttt gccagctcta actggaattg taccaatcct agcttatttt ctagccctct
    24001 atattagtct agctccttct ctttggctgg gtttgccttt gatgctactg tccttgacct
    24061 tattatttgt ctctgttact ttagtgacgg tagtggcagt acatttcttg gctcagacta
    24121 gggtcttcag aaagtatcag tctatttttt cgaatgtgat gattgggata ggagttctca
    24181 tacctttaat atttatcttc tttcttcagt cgacttttgg aagtattgtt gacaaagtta
    24241 gagacattcc atttgtcctt tatcctcttc atatctttta caaaatagca gtggagcctt
    24301 tttcgacaga agccttagtg ggtctgctcg cttggatagg actaactctc ttcctgcttt
    24361 atctgaccaa aaagaaggtc cttcctcgtt tttatgacgt gatcctgctt aacagtgagg
    24421 agaaggtcaa aaaagaacgt cgcagcaagg agaggatttc aactattaaa aagggctttt
    24481 tccgtatggt tttacgctac cacctcaccc tcttgggaca ggggactggc gtgattacag
    24541 tgctttttac aagtgctttc cttccttatc tcatgatgat cagtctgatt tccaaaatcc
    24601 gagattctca gatagttcca gacattcatc ctccatactg gttacccttg ttttttatag
    24661 ctctctttat agcagttgtc aataacaata tcaccagcct gcattcaatt gccttgtcct
    24721 tggagaggga aaatgttgat tttctgaaga gtttaccctt tgactttgct cgttatgtga
    24781 aagtgaaatt ttggattatc tttgctgttc agtccttttt accaattctg actttactcg
    24841 gtctttctct atatctaggc ttgtccatcc tttcgatgat ttaccttctt gtagtctgga
    24901 tcattgccag tgtcatcctt tcttgccacc attactttaa ggacgttaaa aatctgtcaa
    24961 ccaattggag tagcattacg gacctggtga atcgttcaaa tggcatagtc gccatagttt
    25021 tattgtttat ttatagtgca atcctgatgg ctcttgtaat tgggagcata ttcttggttc
    25081 agtctctctc ccctatcctt gccatcagct tgggagtagg agctcttatc gtcttgcttg
    25141 ctcttgctat ttttggctat cattactacc tgtcacgcat attggcagaa atagaaaaaa
    25201 gatgagctgg ttggtcgctt gcttgataaa ttcaattcga caaacgcttt tatagtttgt
    25261 tagaatgtag ttgtaaatga ttaagattgg taatcaaaaa tatataggga ggaatgtttt
    25321 gaataagaaa tataacatag ttctattttt gttgtttata gtttatttat ttgaatattt
    25381 ttcaatttca aaaactttaa ttcctataat gtgtcttttt caagtatttt tgatagaaca
    25441 tatatttaga gttcgaaata gaattatgca gataggtgaa attataatta ttgttgcttc
    25501 tataatatta tttattgata gtatattgag tttgtaacaa aaggcttctc tataaaatca
    25561 aattttccag atatctactg aagctgattt atttctttat ctttcttcta ctacctttgt
    25621 tactaaattt gacagacaca tattgctgat acaacctctc tacctataat ctcacagtta
    25681 acctgaggct agtttcatag tttgccattt gattttcgtt gataaaaaga aaagctcctc
    25741 caagacggaa gagcattttt tattgtgatt cttacacatt tacttcctag ttttgcagga
    25801 agtctagtat accatttttt aaaagaagag taaaaaagaa agggtagttt cttttttgag
    25861 aattgtctaa aagtttgata taatggtagt tatgaataga ataagagtca gcaaaagggt
    25921 tgaaaagaag cttgctaagg ggctagtttt actagaagcc agtgaacttg agaatgtcaa
    25981 tcttaaggat caggaagtag aggtgcaggg tcaggaagga aactttcttg ggactgccta
    26041 tctttctcag caaaacaagg gcttgggctg gtttgtcagc aaagacaagg tggccttcaa
    26101 tcaagctttc tttgaaacct tgtttagaaa agccaaagaa aagagaagca cctactatca
    26161 agatgatttg acaactgcct ttcgtctctt taatcaagag ggagatggct ttgggggtct
    26221 gacagtggac ctttatggcg actacgccgt tttttcttgg tataactctt atgtttatca
    26281 gattcgtcag actatatcag aagcctttag acaggttttc cctgaggttt taggggctta
    26341 tgagaaaatc cgctttaagg ggttggacta tgaatctgcc catgtttatg gtcaagaagc
    26401 acctgacttt ttcactgttt tagaaaatgg tgtcctgtat caagtcttta tgaatgatgg
    26461 cttgatgaca ggaattttcc tagaccagca tgaggttcgc ggtagtttag ttgacggctt
    26521 ggctatgggt aaatccttgc taaatatgtt ttcctacaca gcggcttttt cagtagttgc
    26581 ggccatggga ggagctagcc agacaacttc tgttgatcta gccaaacgtt cacgagaatt
    26641 gtctcaagcg cattttcagg caaatgggct cagcacagac gagcatcgtt ttatagtcat
    26701 ggatgtcttt gagtatttca aatatgccaa acgcaaagac ttgacctacg atgtgattgt
    26761 cctagatccg cctagctttg ctcggaataa aaaacaaact ttctctgtgg ccaaggatta
    26821 tcacaagttg atttcccaga gtcttgagat tttaaatccg ggagggatta tcattgccag
    26881 taccaatgct gccaatgttt cccgtcagaa atttacagaa caaattgata aaggctttgc
    26941 aggaagaagt taccagattt taaacaaata tggtcttcca gcagattttg cctataataa
    27001 aaaagatgaa agtagtaatt acctcaaggt gattagtatg aaggttagta aatgaaatta
    27061 atcgtttcag taatgccaag aagtttagag gaggctcagg ctctggatgc cacgaggtac
    27121 ctggatgccg acatcattga atggcgtgcc gactatctgc ctaaagaagc gattttgcag
    27181 gtagctccag ccatttttga aaaattcgca ggccgtgagt tggttttcac gctacgaact
    27241 cgttccgaag gtggagaaat cgacctttct ccagaagagt atatccatct aatcaaggaa
    27301 gttgcgcaac tctatcaacc agactatatt gattttgagt actatagcta caaggatgtt
    27361 tttgaggaaa tgctgggctt cccaaatctt gttttgagtt accataattt ccaagaaaca
    27421 cctgagaaca tgatggaaat cttgtcagag ttgacgatcc taaatccaaa acttgtcaag
    27481 gttgcggcga tggctcacac ggagcaggat gtcttagact tgatgaacta tacacgaggc
    27541 tttaaaaccc tcaatcctga acaggaatat gtgaccatgt ctatgggtaa ggtgggcaag
    27601 gtctctcgta tcactgcgga tgtgactggt tcgagttggt cttttgccag tctggatgag
    27661 gttagtgccc ctgggcagat ttctctagct agcatgaaaa aaatcaggga gattttggat
    27721 gaagcttgat ggctatacac gtttagctgc agttgttgcc aatcctatta agcattctat
    27781 ttctcccttc atccacaata gagcctttga ggcgacagct accaacggta cttacgtggc
    27841 ttgggagatt gaagcgagtg acttggcaga aacagtggcc aatattcgtc gctaccagat
    27901 gtttggcatc aatctgtcca tgccctataa ggagcaggtg attccttatt tggatgagct
    27961 gagcgatgaa gcgcgcttga ttggtgcggt taatacggtt gtcaatgaga atggcaattt
    28021 aattggatat aatacagatg gcaagggatt ttttaagtgc ttgccttctt ttacaatttc
    28081 aggtaaaaag atgaccctgc tgggtgcagg tggtgcggct aaatcaatct tggcacaggc
    28141 tattttggat ggcgtcagtc agatttcggt ctttgttcgt tccgtttcta tggaaaaaac
    28201 aagaccttac ctagacaagt tacaggagca gacaggcttt aaagtggatt tgtgtgcttt
    28261 agaatatgtt tctgaactgc aagcaaggat tgccgagtcg gatttgctag ttaatgccac
    28321 cagtgtgggc atggatggcc aatcctctcc tgttcctgaa aacatagtct taccagaaac
    28381 tctattagtt gcagatatca tataccaacc ctttgaaaca ccgtttttga aatgggctag
    28441 aagtcagggc aatccagcag tcaatggtct gggaatgttg ctctatcaag ctgcagaagc
    28501 ttttcaactg tggacaggca aggaaatgcc gacagaagag atttggcagt ctttaacaga
    28561 aaaatatcaa taaagaaagg gagactctcc tatgaaaatc agaatcgata ttcctcatca
    28621 tccttatgat attcagattg aaaaaggttg tatggcccag gctggtcagt ggttgcgaga
    28681 actctggcaa ccgcaaaagg tagtcattgt gacagataac catgtagcct ctctctatgc
    28741 agagaaggtc aagctcagcc tagaagatgc tggctttcag gtagctgttt ttgatttctt
    28801 agaaggtgaa gaaagaaaga atttaactac tgttcagaaa gtctatgaat ttctagtcaa
    28861 gcaaggtctg actcgtagcg atggaatcgt ggctcttggt ggtggcgttg ttggggacct
    28921 ggctggcttt gtagcctcta cctatatgcg gggtattcac tttgttcaga ttccgactag
    28981 tttgacagct caggttgatt cttctatcgg tggaaagaca ggcgttaaca caccatttgc
    29041 taaaaatatg gtggggacct ttgcccaacc agatggggtt ctgattgatc cacttgttct
    29101 tgaaaccctc ggaaaaagag agttgattga agggatgggt gaagttatca agtatggctt
    29161 gattgaggat ccagaactgt gggctctctt gacggggctg aatggttctg ttgagagcat
    29221 tttggaacat gcagagacct tgattgaaca ttcttgtcag gtgaagcgca agatggtggt
    29281 tgaagatgag ttggacaatg gtattcgtct ttacctcaat tttggccaca ctattggcca
    29341 tgccatcgaa gcgactgccg gttatggcaa ggtcatgcat ggagaggctg ttgccatggg
    29401 aatggtacag atttccaagg ttgctgagga aaaaggcctc atgccagctg gcattaccca
    29461 atctatcaca gagatgtgtc agaaattcgg cttgcctgtt gactatgaaa attgggaagt
    29521 tgacaagctt tatcaggctc ttactcatga caagaaagcg cgtggtaaca ccttgaaatt
    29581 ggtcttggtg ccagagcttg gttcagcgac cattcaccca gtttctctgg aagagatgaa
    29641 agactacttg gtaaaataag gagagtgtat gagatattta actgcaggag aatcacacgg
    29701 cccccgtcta acagctatta ttgagggaat tccagctgga cttccattga cagctgagga
    29761 tatcaatgag gaccttagac gccgtcaggg tggctacggt cgtggtggtc gtatgaagat
    29821 tgagagtgac caggttgtct ttacttcggg cgttcgccac gggaagacga caggggcgcc
    29881 tattactatg gatgtcatca ataaggacca ccagaaatgg ctggacatca tgtctgcgga
    29941 ggacattgaa gaccgcctta aaagcaagcg gaaaattact catcctcgcc caggtcatgc
    30001 cgatttggtt ggggggatta agtaccgttt tgatgatttg cgaaattctt tggagcgttc
    30061 atcagctcgt gaaaccacca tgcgggtggc agttggtgca gtagccaaac gcctcttggc
    30121 tgagctggat atggagattg ccaaccatgt cgtggtcttt ggtggcaagg aaatcgatgt
    30181 tcctgaaaat ctgacagtcg ctgaaattaa gcaacgagct gcccagtctg aagtttctat
    30241 tgtcaaccaa gaacgaggac aggaaatcaa ggactatatt gacaaaatca aacgtgatgg
    30301 tgataccatc ggtggggttg tggagacagt cgtcggaggc gttccagttg gtcttggttc
    30361 ctatgtccaa tgggatagaa aattggatgc aagattggct caagctgttg tctccatcaa
    30421 tgcctttaaa ggggtggaat ttggtcttgg ctttgaggct ggttatcgta aaggtagcca
    30481 agttatggat gaaattctct ggtctaaaga agacggttat actcgccgta ccaataatct
    30541 aggtggtttt gaaggtggta tgactaatgg gcaacccatc gttgttcgtg gggtcatgaa
    30601 acccattcct actctttata aacctcttat gagtgtggat atcgaaaccc acgaacctta
    30661 taaggcaacc gtggagagaa gtgatccgac tgctcttcca gctgcaggaa tggtcatgga
    30721 agcagttgta gcaacggttc tggcgcaaga aatcctcgaa aaattctcat cagataatct
    30781 tgaggaacta aaagaagcgg tagccaaaca ccgagactat acaaagaact attaaggagt
    30841 tcctatggca aaaacaatct atatcgcagg tcttgggttg attggagcct ctatggcact
    30901 tggtatcaaa cgcgatcatc cagattatga aattttaggt tataatcgta gtcaagcttc
    30961 gagagatatc gccttgaaag aaggcatgat tgaccgtgca acggatgatt ttgctagttt
    31021 tgctcctttg gcagatatca ttattctcag cttgccaatt aaacaaacta tttcctttat
    31081 taaggagttg gccaacttgg acttgaaaga aggtgtcatt atttcagatg ctggttcgac
    31141 caagtcagct attgtggatg cagcggagaa ctatttggct ggcaagcctg ttcgttttgt
    31201 aggagcccat cccatggctg gtagtcacaa gacaggggct gcttcggcag atgtcaatct
    31261 ttttgaaaat gcttattata tcttcacgcc ttcgagtctg acaagtcctg acacgcttga
    31321 ggaaatgaag gagctgcttt caggtcttca tgctcgcttt atcgagattg atgccaagga
    31381 gcatgatcga gtcacttctc agattagcca ttttcctcat attctggctt ctagtctcat
    31441 ggaacagacc gcggtctatg ctcaagaaca tgagatggca aggcgctttg cggccggtgg
    31501 tttccgagat atgactcgaa ttgcggaaag tgagccaggt atgtggactt ccattctctt
    31561 gtctaatcgt gagaccattc tggagcgaat tgaggatttc aaggaacggt tggatgaggt
    31621 tggtcaggct atcagcaagg gagatgaaga gcagatttgg aactttttca accaagcgcg
    31681 tgagcaacgt caggccatgg aaatccataa gcgtggaggt gtggatagtt cttacgacct
    31741 ctatgtcgac gttcccgatg aagaagatgt catcttgagg attttggaac tactacgtgg
    31801 aacttccttg gtcaatattc atatcaacga ggaaaaccgt gaggatattc acgggattct
    31861 acaaatttca tttaaaaatg ctcaagactt ggaaagagct gagcatctaa taacagaaaa
    31921 taccgactac acagtcgttg tcaaataagg agaaaatcat gtcaaatatt tacgatagtg
    31981 caaacgaact tagtcgcggt ctacgcgaat taccagaata caaggctgtc aaagcagcta
    32041 aagatgcgat tgcagcagat gctgaggcaa gcaaaatctt tacagattat cttgcctttc
    32101 aagaggaaat tcaaaaacta gcacagacag gtcaaatgcc agatgcgtcc ttccaagata
    32161 agatggaagg ctttggcaag cagattcaag gaaatagcct cttgtcagaa ttctttacta
    32221 agcaacaaca attggcaatt tacctttctg acattgaaaa aattgttttc gaaccagttt
    32281 cagaattgct aaaataagaa aataactatc ctaaagtcag gaatttttaa ggaatttctg
    32341 gctttttatg ataaaatagg taaaagtatt gcaagtatga ggtccagtat gaaactaaaa
    32401 acaaacatta gccacttaca tggcagtatc cgcgtcccag gtgacaagtc tatcagccac
    32461 cgttccatta tctttggaag tttagctgag ggagagacca aggtttatga tattttgcgg
    32521 ggtgaagacg tcctttcaac catgcaggtc tttcgtgatc ttggtgtaga gattgaggat
    32581 aaagatgggg ttgttaccat tcaaggtgtc ggtatggacg gcctaaaagc tccacaaaat
    32641 gcccttgata tgggaaattc tggaacctcg attcgtctga tttcaggtgt ccttgctggt
    32701 gcagacttcg aagtagaaat gttcggagac gatagtcttt ccaaacgtcc tatggaccgt
    32761 gtgacgattc cactgaaaaa aatgggcgtt agcatttcag ggcaaactga gcgagacttg
    32821 cctccccttc acttaaaagg gacgaaaaaa ctagcaccta ttcagtatga gttgccaatt
    32881 gcctctgccc aagtcaagtc agccttgatg tttgcggcct tgcaggctca gggagagtca
    32941 gtgattatcg aaaaagaatg cacccgtaat catactgaag atatgctgca acaatttggt
    33001 gctcatttaa gtgtggatgg caagaaaatc acagtccaag gacttcaaaa actgacagga
    33061 caaaaggtgg ttgttccagg agatatttcc agtgcagcct tttggttggt cgcaggtttg
    33121 attgttccga attctcgtct agtgctgcag aatgtgggga ttaacgaaac gcgtaccggt
    33181 attattgatg tcattcgtgc catgggtgga aaattagaag ttactgaaat tgacctagtg
    33241 gctaaatctg ctactttgac tgttgagtct tctgacttgc aaggaacaga gattggcggt
    33301 gccttgattc cacgcttgat tgatgaattg cctattattg cccttttggc gacccaagcc
    33361 caaggtgtaa cagttatcaa ggatgctgag gagctcaagg tcaaggaaac agaccgtatt
    33421 caggttgtgg cagacgcctt aaatagtatg ggagcagata ttactcctac ggtagatggg
    33481 atgattgtca aaggaaaatc agctcttcac ggtgctagag tcaatacgtt tggtgaccac
    33541 cgtatcggca tgatgacagc tatcgcagcc ctcttggttt cagatggaga ggtggagctt
    33601 gaccgtgcag aagccatcaa taccagctat cctagtttct ttgatgattt ggagagcttg
    33661 attcatggct aaggtgttat tagggtttat gggggctgga aaatcgacta ttgcaagagg
    33721 attggaccct aattaccttg atatggatgc tctgattgag aagcgcctag gtatatccat
    33781 tgcgaatttt ttcgctgaaa agggagaatc agcctttcgt caggtagaat cagaagtcct
    33841 agctgattta ctacaaacag accaagtcgt gtcaactgga ggaggagtgg ttatttctca
    33901 gagaaatcgt gacttactca agactaatac agataacatc tacctgaaag cagattttga
    33961 aaccctctac ctacgtatcg caactgataa ggacaatcag cgaccgcttt ttctaaataa
    34021 tagcaaggaa gaactagtag ctatttttca agaaagacag gcttggtatg aggaagtggc
    34081 tagtcgggtt ttggatgtga ccaagctaag cccagaggaa attatagagg aactaagatg
    34141 aaaattgctt atctaggtcc caagggatca ttttcacacc acgttgtgca gacagctttt
    34201 cctcatgagg aattgcaggc ttttgccaac attacagatg tcatcaaggc ttatgagcaa
    34261 ggattagtgg actattctgt ggtgccagtt gaaaactcta ttgagggtag tgttcatgaa
    34321 accttggact atctttttca tcaggctcac atccaaacag tagcagaaat cgttcagcct
    34381 attcatcagc agttgatggt ggttccaggc catactaaga ttgaaaagat tttttcacat
    34441 ccacaggcat tggctcaagg aaagaaattc atcgatgaac aatatccaga ggctcaaatc
    34501 gaggtaacag ctagtacagc ttatgcggcc cgttttattt ccgaacatcc agaccagccc
    34561 tttgcagcaa ttgcacctag aagttctgct gaagaatatg gattggaact gattgccgag
    34621 gatattcagg aaatggaagc caatttcaca cgtttctggg ttctaggagc tggaaagcct
    34681 agtattccct tgcaagcaca aactgaaaag atgagtttgg ccttgacatt acctgacaac
    34741 cttccaggtg cactttataa ggccctgtcg acctttgctt ggcgaggaat tgacttgaca
    34801 aaaattgaaa gtcgtccact caagacagca ctgggtgaat acttttttat tatcgatgtg
    34861 gattataccg ataaggactt ggtccacttt gcccaaaaag aattagaagc gattggaatc
    34921 cagtataaaa ttctgggcgc ctatcctatt tatccaatat cagaccatgg aaaggagaga
    34981 agatgagtaa agaaaatccc ttaagtcatc atgagcagtt gcgttatgat tatttgctaa
    35041 aaaatattca ctatctcaat gagagagaaa aaaatgagtt tgcctatttg caagaaaagc
    35101 taactcttgc taggggaaat agtagctcta gcttggaaca agaaagagaa gagcaggttg
    35161 acttaccaag ctatgcgaac cggagtcgct cacaatccaa atcacaagca ctctcttcac
    35221 ctccaaaaaa gaaaagacgg aagctccgtc ttaaacgaat ttttatggtg attttttcac
    35281 ttttagtctg tgtggctttg gccatggtat tcatgttttt gcgtggttac caagatgcta
    35341 gcgcaaagaa aactattgat gcccgggcag ctcaagtaga agtctttaat ggtcaggaca
    35401 ctagagatgg agttaatatt ttaatcatgg gtactgatgg tcgaatcggc cagaacagtg
    35461 ttgagacacg aactgactct attatggtat taaatgtcgg gggctcagat aagaaaatga
    35521 agctagtcag tttcatgcgt gataatttgg tctatataga tggttatagt caagtgatta
    35581 acggtagaaa acagacagat aacaagttaa acgtagccta cgagttagga gaacaagagg
    35641 ggcaaaaagg ggcagaaatg gttcgccaag tcttgaaaga taattttggc ttggacatta
    35701 agtactatgc cttggttgat ttccaggcct ttgccacagc gattgacacg cttttccctg
    35761 atggggtgac gattgatgct caattttcaa cattgaatgg gcgtccccta acagaagcta
    35821 cagtcggaga tgatttatac gctaccgaga ctgagtctcc aacccaaacc attaaagtcg
    35881 gaaaacagca gatgaatggc tcgaccctgc tcaattatgc tcgtttccgt gatgatgatg
    35941 aggcggatta cggccgtaca aaaagacagc aacaagtttt aacagcaatt ttagagcaaa
    36001 ttaaagatcc tactaaactt ttcactggtt ctgaagctct tggaaaggtt tttgctatga
    36061 cctcaaccaa cgtaccctat actttcctcc taacaaacgg tttatctgtt ttggatggag
    36121 caaaaaatgg tattgaaaaa ttgacgattc cagaactggg tgactgggta gatgcctatg
    36181 atgtttatgg aggcttgggc ttgctggttg atcaaaacaa atatcaaacc aagctcgctc
    36241 aaatgggctt gagataagat aatactcaat gaaaatcaaa gtgcaaacta ggaagctagc
    36301 cgcaggctgc taaaaacaca gttttgaggt tgtagataag actgacgaag tcagttacct
    36361 atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttcgaagag tataagacag
    36421 aaaaatcaaa gtttgatagc tatttggata gcagtcaggc tttgattttt tacagtctgc
    36481 aatagatttt caccccttgt ttgtggtata atgaaacgat acgatagaaa gaataatgaa
    36541 caatatgact gatttaaaag caattcaggc tcgtagtctg gagatggctg aatattttgt
    36601 ggccttttgt aaagaacatg atttgatctg ttatctctgt ggcggaggcg ctattggtgc
    36661 ccttcgaaac aagggattta ttccttggga cgacgaccta gactttttta tgcctcgtaa
    36721 agattatgag aaattagcag aattatggcc tcgttatgca gatgaacgtt atttcttgtc
    36781 aaagagtcac aaggattttg ttgatcgtaa tctttttatt accattcgtg acaaggaaac
    36841 cacctgtatc aagccttatc agcaggattt ggatttgcca catggtctgg ccttggatgt
    36901 tttgcctttg gattattatc cgaaaaatcc agctgagcgg aaaaaacagg ttcgttgggc
    36961 cttgatttat tcactctttt gtgcgcaaac tattccagaa aagcatggtg ctcttatgaa
    37021 atggggaagt cgcattttac tgggtttgac tccaaaatct ctccgttatc gcatctggaa
    37081 aaaagctgag aaagaaatga ctaagtatga tttggctgat tgtgatggca ttacagaatt
    37141 atgctcaggt cctggctaca tgagaaacaa gtacccaatc acatcttttg aagacaatct
    37201 tttcttgcca tttgaaggaa cagagatgcc tattccaatc ggctatgatg tctatctcag
    37261 aactgttttt ggggattata tgacgcctcc accagcagac aagcaggtac cgcatcatga
    37321 tgctgtcatc gctgatatgg ataagtctta tacagaatac aagggagaat atggtggcta
    37381 agaaaaaaat cttatttttt atgtggtctt tttctcttgg aggtggtgca gagaagattc
    37441 tatcaaccat tgtttcaaat ctggatccag aaaagtatga tattgatatt cttgaaatgg
    37501 agcactttga caagggatat gaatctgttc caaagcatgt acgcatttta aaatcccttc
    37561 aagattatcg ccaaaccaga tggttacgag cttttttgtg gagaatgaga atttattttc
    37621 caagactgac tcgtcgtttg cttgtaaaag atgattatga tgttgaagtt tcttttacca
    37681 ttatgaatcc accactgttg ttctctaaaa gaagagaagt caagaagata tcttggattc
    37741 atggaagtat tgaagaactt cttaaggata gctctaaaag agaatcacat agaagccagt
    37801 tggatgctgc gaatacaatt gtagggattt caaaaaagac catcaattct atcaaggaag
    37861 tttatccaga ttatgcttct aaattacaga caatctacaa tggatatgat tttcagacta
    37921 ttctagaaaa atctcaagag aagatcgata tcgagattgc tcctcaaagt atctgtacta
    37981 tcggacggat tgaggaaaat aagggttctg accgtgtagt ggaagtgata cgattattac
    38041 accaagaggg aaaaaactat catctctatt ttatcggggc tggtgatatg gaagaggaac
    38101 tgaaaaaacg agtcaaagag tatgggattg aggactatgt acatttcctt ggttatcaaa
    38161 aaaatcctta tcagtattta tctcagacga aagttctctt gtctatgtct aaacaagaag
    38221 gttttcctgg agtgtatgtg gaggccttga gtctgggact cccttttatc tctacggacg
    38281 ttggaggggc tgaggaatta tcccaagaag gacgatttgg acaaatcatt gagagcaatc
    38341 aagaggcagc tcaggcgatt actaattaca tgacttctgc ctcaaacttt gatgtcgatg
    38401 aggctagcca attcattcaa caatttacaa ttacaaaaca aatcgaacaa gtagaaaaac
    38461 tattagagga gtagcatgga aactgcatta attagtgtga ttgtgccagt ctataatgtg
    38521 gcgcagtacc tagaaaaatc gatagcttcc attcagaggc agacctatca aaatctggaa
    38581 attattcttg ttgatgatgg tgcaacagat gaaagtggtc gcttgtgtga ttcaatcgct
    38641 gaacaagatg acagggtgtc agtgcttcat aaaaagaacg aaggattgtc gcaagcacga
    38701 aatgatggga tgaagcaggc tcacggggat tatctgattt ttattgactc agatgattat
    38761 atccatccag aaatgattca gagcttatat gagcaattag ttcaagaaga tgcggatgtt
    38821 tcaagctgtg gtgtcatgaa tgtctatgct aatgatgaaa gcccacagtc agccaatcag
    38881 gatgactatt ttgtctgtga ttctcaaaca tttctaaagg aatacctcat aggtgaaaaa
    38941 atacctggga cgatttgcaa taagctaatc aagagacaga ttgcaactgc cctatccttt
    39001 cctaaggggt tgatttacga agatgcctat taccattttg atttaatcaa gttggccaag
    39061 aagtatgtgg ttaatactaa accctattat tactatttcc atagagggga tagtattacg
    39121 accaaaccct atgcagagaa ggatttagcc tatattgata tctaccaaaa gttttataat
    39181 gaagttgtga aaaactatcc tgacttgaaa gaggtcgctt ttttcagatt ggcctatgcc
    39241 cacttcttta ttctggataa gatgttgcta gatgatcagt ataaacagtt tgaagcctat
    39301 tctcagattc atcgtttttt aaaaggctat gcctttgcta tttctagaaa tccaattttc
    39361 cgtaagggga gaagaattag tgctttggcc ctattcataa atatttcctt ataccgattc
    39421 ttattactga aaaatattga aaaatctaaa aaattacatt agaacggggg tgaccaagtg
    39481 attgatggga aacgattatt atttagtttg accatagtca gttatgcctt gacgctagta
    39541 agtggaattg tgtatctgtt taataataat aatgttagct tactttctac tttattgttc
    39601 ttgttggtta gtagcttaat tgcttgttgg aatgatatca agtattactt aatccatttt
    39661 attttctatt taaccatttt tgtatttctg gtatcaagac cgaccattga ttattttagg
    39721 gatggtgctt tggataccta tcatccaata gcctatcgtt ttgccttcat agttgtcatg
    39781 gtttcgattc tgggcttgac tacaggaggc gtcctggctc gttacttcgt agctaggaag
    39841 aaaataaaag tagcaaatat aggaagttct ctaaaagagg tttatatcaa gcggttacgc
    39901 tttgtatcac taggagtttt tcttctaact tatcctttct atttcattcg gttatttgaa
    39961 cggctcttgt atcgtttgca gacttcctac tatgcctact atgcaaattt tgaaagtaaa
    40021 ctgccttatt ttacctacat tttgtctacc tttacggtct atgcaatgtg tatgtatctg
    40081 gcaaccaagc caaagaaatt gcaggccaca gcagtgcttg tctcctttat tgcagctaat
    40141 actattcatt tggcaattgg gacacgaaat ccctttattt taagtatttt atttgctttt
    40201 gtttattact ttatgcggga gcaaactgaa aaaggaaaat ggattgggtt taaagaaaag
    40261 ttagcgattt ttgtaggttc tcctattctc atgttagcga tgggagtact caattatgta
    40321 cgggataata tccaagtttc ccatacaggt ttctgggata tcttacttga ctttatctat
    40381 aaacaaggga ctagttttgg tgttctggct cgaggttttc tatttaacag tagcctccct
    40441 taccgagatt tccgtaattt tacttttggt cctgttcttg attattttgc aagggggagt
    40501 ttgggagcca ttttcggagg aaaagccttt gaacatacaa ccaatagtgt ggaactagct
    40561 attgatagta atagttatgc ccacaatcta tcctatcttg tcttgaacaa ggaatacttg
    40621 aaagggcatg gtatcggaag tagttatatc atggagttgt ataccgacta tggtatgatt
    40681 ggagtctttc tgcttagttt cttactcggc gtattattta tagccatgct gcaagtagcc
    40741 tatcgctcaa ggacaatcct atttgcttta tccctactca tcttgaataa tctattcttt
    40801 atgccaagaa gcagcttttc agaaagtttc ttcaatttat ttacaatgca attctgggga
    40861 attgttcttg tgatgatatt cgtagcaaaa atacttacaa aagaaaacca gtatctacta
    40921 aacaaaggag aaaaaaatca tgtttgaaca ttattcagta gctgatttat ttgcaaatct
    40981 atacaaaaaa cgaaaagcaa atattctagc tctcatcgct ttatttgctc tcattgctgt
    41041 accatttaca attaaagcag ttaggaataa aaacactgtc aaagatacaa caagttattc
    41101 aacttatctt atctataaaa tcactcctcc agaagattcg gccaaaacga ttttgaatca
    41161 tcaaattggt ggttatagtg atttttatgg gaaattgatt gatggtaatt tgaatggagc
    41221 ttatcttttc aatgatgtag aacccagtga gttgaaaaaa attgccagtg aattagacac
    41281 gacagaaaca accttgaaaa attcaacgaa tgactattgg tggaaaaaat tgaccgtcta
    41341 ctatatgatt gacgatgcag gggttggtgt gaaaattttg acatcaagta aagatgccaa
    41401 tgacttgtta gagaaaaaaa ttgatgggtt gattgagaaa tttaaacatg cctatgcaaa
    41461 tgtgaaaatt gaaaaactgg aaaccatcaa ctctaaagaa ttgaacgcaa atggtgaaac
    41521 agcgcttggc ttaaatgtga aaaatctgat tcttcgttta gttgttattg gagtggtttg
    41581 tgtgattttg gttgtgatgg gaaatgtgtt agtttatctc tttaatccaa caatcaatag
    41641 agtaggtgat ttttctcagt atcaaattga ttttgtaaca gagattacaa caattgctaa
    41701 cctagcagat gttttgtcat acaaaaatac tggacaggaa ttgaccatcg ttagctcaaa
    41761 taaagctatc ctagataaat tgaaacagag tcaagaagct ttaaaaggaa tgcattttgt
    41821 agatttacag gatgtatcat ctcttttgga aagagataca gtccttcttg ttgaagagta
    41881 cggagtgact cgttataaga aatttgagca aagtcttcaa attctcagaa acttaaatcg
    41941 ttctatcctc ggcgtagcaa cctttaaatt ataagtattc tgatgtataa ggtcttcaaa
    42001 gtcggctaag agccgatttt gaaggctttt tctatctgtc tgcagaaatt ttcttttgga
    42061 gtctcctata gaaagaccct agggaaaatc tatccgtata gaggagcctt cttttgataa
    42121 aatcgtaaaa atctagtata atagatagaa ctgaaagtat gaggttacta gcaatgaaaa
    42181 tgaaacaaat tagtgataca actttaaaaa tcacgatgtc tttagaggat ttgatggatc
    42241 gtggaatgga gattgctgac tttctcgttc ctcaagaaaa aacagaagag ttcttttatg
    42301 ctatcttgga tgagctagag atgcctgata gctttctgga tacaggcatg ttgagcttcc
    42361 gtgtgactcc aaaacctgat aaggtagatg tctttgtgac caagtcaaag attgaccaaa
    42421 atctagattt tgaagactta tcggatttgc cagatatgga agaattggct caaatgtctc
    42481 cagatgaatt tatcaaaacc ctggaaaaaa gcatcgcaga caaaaccaag gatgatatcg
    42541 aagccattca atctcttgag caagttgaag ccaaggaaga agagcaagag caagctgaac
    42601 aagaagctga gagtaagaaa gaaccttaca tctactacat cctttctttt gctaagttgg
    42661 ctgacttggt agcttttgcc aagacagtga cttttgaaat ggaaacttct gaactctaca
    42721 aaatgaacga gcgctattat ttgaccattt tagtggatat tgaaaatcat ccaagcccat
    42781 atccagcttg gctgttggcc cgtatgcgcg agtttgcaga cgatagtgat atcagtcgct
    42841 cagtcttaca agagtatggt caagtcttga tgagtcacga tgcagtgctc aatctgcaaa
    42901 aaatcggcta atcctttctg gaaagctatt ttcagatttt aagaagagcg aatcgtctga
    42961 ttcgtttttt ctttttatac tgaaatagtg atttactata ataggaattt tcacaaaatt
    43021 ctgttataat ggctatatta gaaaatttcg aggagataaa gatgacagtt aaaattgctt
    43081 tactaggatt tggtaccgtt gcaagtggtg tgcctttcct cctaaaggaa aatggaggaa
    43141 aaatcaatca atcagcacat tcagatatca aagttgctaa ggtattggtc aaggatgaag
    43201 atgaaaaaaa tcgcttgctt gcagcaggga atgactttaa ctttgtaacc aatgtggatg
    43261 atattttatc agaccaagat attactatcg tagtggaatt gatggggcgt attgagcctg
    43321 ctaaaacctt tatcactcgt gccttggaag ctggaaaaca cgttgttact gctaacaagg
    43381 accttttagc tgtccatagc gcagaattgc tagaaatcgc tcaagctaac aaggtagcac
    43441 tttactacga agcagcagtt gctggtggga ttccaattct tcgtacttta gcaaattcct
    43501 tggcttctga taaaattacg cgcgtgcttg gagtagtcaa cggaacttcc aacttcatgg
    43561 tgaccaagat ggtggaagaa ggctggtctt acgatgatgc tcttgcggaa gcacaacgtc
    43621 taggatttgc agaaagcgat ccgacgaatg acgtagatgg gattgatgca gcctacaaga
    43681 tggttatttt gagccaattt gcctttggca tgaagattgc ctttgatgat gtagcccaca
    43741 agggaatccg caatatcaca ccagaagacg tagctgtagc tcaagagctt ggttacgtag
    43801 tgaaattggt tggttctatt gaggaaactt cttcaggtat tgctgcagaa gtgactccaa
    43861 ccttcctacc taaagcgcac ccacttgcta gtgtgaatgg cgtaatgaac gctgtctttg
    43921 tagaatctat cggtattggt gagtctatgt actacggacc aggtgcgggt caaaaaccaa
    43981 ctgcaacaag tgttgtagct gatattgtcc gtatcgttcg tcgtttgaat gatggtacca
    44041 ttggcaaaga cttcaacgaa tatagccgtg acttggtctt ggcaaatcct gaagatgtca
    44101 aagcaaacta ctatttctca atcttggcta cagactcaaa aggtcaggtc ttgaagttgg
    44161 ctgaaatctt caatgctcaa gatatttcct ttaagcaaat ccttcaagat ggcaaagagg
    44221 gtgacaaggc gcgtgtcgtt atcatcacac acaagattaa taaagcccag cttgaaaatg
    44281 tctcagctga attgaagaag gtttcagaat tcgacctctt gaataccttc aaggtgctag
    44341 gagaataaga tgaagattat tgtacctgca accagtgcca atatcgggcc aggttttgat
    44401 tcggtcggtg tagctgtaac caagtatctt caaattgagg tctgcgaaga acgagatgag
    44461 tggttgattg aacaccagat tggcaaatgg attccacatg atgagcgtaa tctcttgctc
    44521 aaaatcgctt tgcaaattgt accagacttg caaccaagac gcttgaaaat gaccagtgat
    44581 gtccctttgg cgcgcggttt gggttcttcc agctcggtta tcgttgctgg gattgaacta
    44641 gccaaccaac tgggtcaact caacttatca gaccatgaaa aattgcagtt agcgaccaag
    44701 attgaagggc atcctgacaa tgtggctcca gccatttatg gtaatctcgt tattgcaagt
    44761 tctgttgaag ggcaagtctc tgctatcgta gcagactttc cagagtgtga ttttctagct
    44821 tacattccaa actatgaatt acgtactcgc gacagccgta gtgtcttgcc taaaaaattg
    44881 tcttataagg aagctgttgc tgcaagttct atcgccaatg tagcggttgc tgccttgttg
    44941 gcaggagaca tggtgaccgc tgggcaagca atcgagggag acctcttcca tgagcgctat
    45001 cgtcaggact tggtaagaga atttgcgatg attaagcaag tgaccaaaga aaatggagcc
    45061 tatgcaacct acctttctgg tgctgggccg acagttatgg ttctggcttc tcatgacaag
    45121 atgccaacaa ttaaggcaga attggaaaag caacctttca aaggaaaact gcatgacttg
    45181 agagttgata cccaaggtgt ccgtgtagaa gcaaaataaa gaatagaaga taggatgggg
    45241 aaactcttga ccagagggtt tcatatcctt tttgtgaaaa gaagtttata ctcaatgaaa
    45301 atcaaagagc aaactaggaa gttagccgca ggctgctcaa aacagtgttt tgaggttgtg
    45361 gatagaactg acgaagtcag ctcaagacac tgttttgagg ttgcagatag aactgacgaa
    45421 atcagtaaca tacctacggt aaggtgacgc tgacgtggtt tgaagagatt ttcgaagagt
    45481 attagttaaa aacgtgataa aggagaaata aagatggcag aaatttatct agcaggtggt
    45541 tgtttttggg gcctagagga atatttttca cgcatttctg gagtgctaga aaccagtgtt
    45601 ggctacgcta atggtcaagt cgaaacgacc aattaccagt tgctcaagga aacagaccat
    45661 gcagaaacgg tccaagtgat ttacgatgag aaggaagtgt cactcagaga gattttactt
    45721 tattatttcc gagttatcga tcctctatct atcaatcaac aagggaatga ccgtggtcgc
    45781 caatatcgaa ctgggattta ttatcaggat gaagcagatt tgccagctat ctacacagtg
    45841 gtgcaggagc aggaacgcat gctgggtcga aagattgcag tagaagtgga gcaattacgc
    45901 cactacattc tggctgaaga ctaccaccaa gactatctca ggaagaatcc ttcaggttac
    45961 tgtcatatcg atgtgaccga tgctgataag ccattgattg atgcagcaaa ctatgaaaag
    46021 cctagtcaag aggtgttgaa ggccagtcta tctgaagagt cttatcgtgt cacacaagaa
    46081 gctgctacag aggctccatt taccaatgcc tatgaccaaa cctttgaaga ggggatttat
    46141 gtagatatta cgacaggtga gccactcttt tttgccaagg ataagtttgc ttcaggttgt
    46201 ggttggccaa gttttagccg tccgatttcc aaagagttga ttcattatta caaggatctg
    46261 agccatggaa tggagcgaat tgaagttcgt tctcgttcag gcagcgctca cttgggtcat
    46321 gttttcacag atggaccgcg ggagttaggc ggcctccgtt actgtatcaa ttctgcttct
    46381 ttacgctttg tggccaagga tgagatggaa aaagcaggat atggctatct attgccttac
    46441 ttaaacaaat aaaacagaga gggtggggtt tcccactttc ttcatttcta gaatatgaat
    46501 agaagggatt tatgaaacac ctattatctt acttcaaacc ctacatcaag gaatcaattt
    46561 tagccccctt gttcaagctg ttagaagctg tttttgagct cttggttccc atggtgattg
    46621 ctgggattgt tgaccaatct ttacctcagg gagatcaagg tcatctctgg atgcagattg
    46681 gtctgctcct tatctttgca gtaattggcg ttttagtggc cttgatagct caattttact
    46741 cagcaaaggc agcagtaggt tttgctaagg aattgacaaa cgatctttat cgtcatattc
    46801 tttccttgcc caaggatagc agaaaccgtc tgacaacttc tagtttggtc actcgcttga
    46861 cttcggatac ctaccagatt cagactggta tcaatcaatt cctgcgtctc tttttacgag
    46921 cgcccattat tgtttttggt gccattttta tggcttatcg aatctcagct gagttgactt
    46981 tctggttctt agtcatggtt gccattttga ccattgtcat tgtagggtta tctcgattgg
    47041 tcaatcctct ctacagtagt ctcagaaaga aaacggacca actggttcag gaaacgcgcc
    47101 agcaattgca agggatgcgg gttattcgtg cttttggtca agaaaaacga gagttacaga
    47161 tttttcaaac ccttaaccaa gtttatgcta gattacaaga aaagacaggt ttcttgtcta
    47221 gtttattaac acctctgacc tatctgattg tcaatggaac tcttctcgtt attatctggc
    47281 aaggctatat ttcaattcaa ggaggagtgc tcagtcaagg tgctctcatt gctcttatca
    47341 attacctctt acagattttg gtggaattgg tcaagctagc catgttgata aattccctca
    47401 accagtccta tatttcagcc aagagaatcg aggaggtctt tgcggaatct cccgaaaaca
    47461 tccattcaga attagaacaa aagcaagtta ccagtggtcg ggttttacaa gtccaagaat
    47521 tggcttttac ctatcctgat gcggcccagc cttctctgag agacatttcc tttgatatga
    47581 ctcaaggaca aatccttggt atcattgggg ggactggttc tggtaaatca agcttggtgc
    47641 aactcttact tggactttat ccagtagaca aggggaacat tgacctttat caaaatggac
    47701 gtagtcctct taatttggag cagtggcggt cttggattgc ctatgtacct caaaaggtcg
    47761 aactctttaa aggaaccatt cgttccaact tgactctagg tttcaatcaa gaagtatctg
    47821 accaggaact ctggcaggcc ttggagattg cgcaagctaa ggattttgtc agtgaaaagg
    47881 aaggactctt ggatgctcta gttgaggcag gggggcgaaa tttctcaggt ggacaaaaac
    47941 aaagattgtc tatcgcccga gcagtcttgc gccaagctcc gtttctcatc ctagatgatg
    48001 cgacctcagc actggacacc attacagagt ccaagctgtt gaaagctatt agagaaaatt
    48061 ttccaaacat gagcttaatt ttgatctctc aacgaacctc gactttacag atggcggacc
    48121 agattctcct cttggaaaaa ggtgagttgc tagctgttgg caagcacgat gacttgatga
    48181 aatccagtca agtctatcgt gaaatcaatg catcccaaca tggaaaggag gactagaatg
    48241 aaacgacaaa ctgtaaacca gacgctcaaa cgtttagccg tagatttagc aaaccatccc
    48301 ttcctccttt tcctagcctt tctaggaact attgcccaag ttggcttatc aatttaccta
    48361 cctattctga ttgggcaggt cattgaccaa gtcctagtgg ctggttcatc accagttttt
    48421 tggcagattt ttctccagat gctcttggtg gtaataggaa atactctggt acaatgggcc
    48481 aatcctctcc tctataatcg tctaatcttc tcttatacca gagatttacg ggggcgaatc
    48541 atccataaac tccatcggtt accgattgcc tttgtagata ggcaaggtag tggagagatg
    48601 gttagtcgtg taaccacgga catcgaacag ttggcagctg gcttgaccat gatttttaac
    48661 caatttttca ttggtgtttt gatgattttg gttagtattc tagccatgct ccaaattcat
    48721 ctcctcatga ctctcttagt cttgctattg acgccactgt ccatggtgat ttcacgcttt
    48781 attgccaaga gatcctatca tctcttccag aagcaaacag agacgagggg gattcagact
    48841 cagttgattg aagaatcgct tagccagcag actataatcc agtccttcaa tgctcaaaca
    48901 gaatttatcc aaagattgcg tgaggctcat gacaactact caggctattc tcagtcagcc
    48961 atcttttatt cttcaacggt caatccttcg actcgctttg taaatgcact catttatgcc
    49021 cttttagctg gagtaggggc ttatcgtatc atgatgggtt caaccttgac cgtcggtcgt
    49081 ttagtgactt ttttgaacta tgttcagcaa tacaccaagc cctttaatga tatttcttca
    49141 gtgctagctg agttgcaaag tgctctggct tgcgtagagc gtatctatgg agtcttagat
    49201 agccctgaag tggctgaaac aggtaaggaa gtcttgacca gtgaccaagt taagggagct
    49261 atttccttta aacatgtctc ttttggctac catcctgaaa aaattttgat taaggacttg
    49321 tctatcgata ttccagctgg tagtaaggta gccatcgttg gtccgacagg tgctggaaaa
    49381 tcaactctta tcaatctcct tatgcgtttt tatcccatta gctcgggaga tatcttgctg
    49441 gatgggcaat ccatttatga ttatacacga gcatcattga gacagcagtt tggtatggtg
    49501 cttcaagaaa cctggctcac acaagggacc attcatgata atattgcctt tggcaatcct
    49561 gaagccagtc gagagcaagt aattgctgct gccaaagcag ctaatgcaga ctttttcatc
    49621 caacagttgc cacagggata cgataccaag ttggaaaatg ctggagaatc tctctctgtc
    49681 ggccaagctc agctcttgac catagcccga gtctttctgg ctattccaaa gattcttatc
    49741 ttagacgagg caacttcttc cattgataca cggacagaag tgctggtaca ggataccttt
    49801 gcaaaactca tgaagggccg cacaagcttc atcattgctc accgtttgtc aaccattcag
    49861 gatgcggatt taattcttgt cttagtagat ggtgatattg ttgaatatgg taaccatcaa
    49921 gaactcatgg atagaaaggg taagtattac caaatgcaaa aagctgcggc ttttagttct
    49981 gaataagcca ttctcttttg aaagtttatg gacgaaaaaa gttgccttcg agtgactttt
    50041 ttgttacaat agctagaaaa attgttcact gtaatactca atgaaaatca aagagcaaac
    50101 taggaagcta gccgtaggtt gctcaaagca cagctttgag gttgtagata agactgacga
    50161 agtcagttca aaacactgtt ttgaggttgc agatagaact gacgaagtca gtaaccacac
    50221 ctacggcaaa gtgaatctga agtggtttga agagagtaca acttgtcttt tagaaaagga
    50281 gcctacaatg aaagtctttc agcatgtaaa tatcgtgact tgtgatcaag atttccatgt
    50341 ttatcttgat ggaatcttag cagtcaagga ttctcaaatc gtctatgtcg gtcaagataa
    50401 gccagcgttt ttagagcaag ctgagcagat tatagactat cagggagctt ggattatgcc
    50461 tggtttggtc aattgtcaca cccattctgc aatgacaggt ctgagaggga tccgagatga
    50521 cagcaatctc catgaatggc tcaatgacta tatctggcca gcagaatctg agtttactcc
    50581 cgacatgact accaatgcgg tcaaagaagc cctgacagag atgctccagt caggaacaac
    50641 aacctttaac gatatgtata atcccaatgg tgtggatatt cagcaaattt atcaggtggt
    50701 gaaaacttcc aagatgcgtt gttatttttc tccgactctc ttttcttcag agacagaaac
    50761 aactgctgag actataagca gaactcgatc catcatagac gaaatcttaa aatataaaaa
    50821 tccaaatttc aaggttatgg tagcacctca ttctccgtat agctgcagta gagacttgct
    50881 ggaagcgagt ttggaaatgg caaaagagct aaatattccg ctccatgtcc atgtggcgga
    50941 gaccaaggag gagtcaggaa ttatcctcaa acgatacggc aaacgccccc ttgcttttct
    51001 tgaagaactg ggttatttag atcatccgtc cgtatttgct cacggggtcg aattaaacga
    51061 gagagaaatt gaacgcttgg catcttctca agtggctatc gcccacaatc ctatcagtaa
    51121 cctcaaactg gcatcaggaa ttgctccaat tatccagctc caaaaagcgg gagtagcagt
    51181 cggaattgcg actgactcgg ttgcttccaa taacaatcta gatatgtttg aggaaggaag
    51241 gactgcagct cttcttcaga agatgaaaag tggggatgcc agccagtttc caatcgaaac
    51301 agctctcaag gtactgacaa tcgaaggggc taaggccctt ggaatggaaa atcagatagg
    51361 aagtctggaa gtcggcaagc aagcagattt tctggtcatt caaccacaag ggaaaattca
    51421 tctccaacct caggaaaata tgctgtctca cctggtttat gcagttaaat ctagtgatgt
    51481 agatgatgtt tatatcgccg gagaacaggt tgttaagcaa ggtcaagtcc tgacagtaga
    51541 actttaaaag aaaaatcacg aaaaatttta aaaaaagttt gcaaaaatct tgcattcttt
    51601 ttttgactat gctatactta tatacggttt aaaaaaactg cctaagacag taggggagct
    51661 cgactcataa atatcctacc gaggacaaga cgtatcatgt aaaaagaagc gtattgtact
    51721 ttcgtgtcta ggtttgggcg cgtttttctt tttgaaaaat tccccaagca aaataattac
    51781 ggaggtgaac acactaatga gtgaagcaat tattgctaaa aaagcggaac tagttgacgt
    51841 agtagctgaa aaaatgaaag ctgctgcatc tatcgtcgtt gtagacgctc gtggtttgac
    51901 agttgagcaa gatacagttc ttcgtcgtga gcttcgtgga agcgaagttg agtataaagt
    51961 tattaaaaac tcaatcttgc gtcgtgcagc tgaaaaagct ggtcttgaag atcttgcatc
    52021 tgtatttgtt ggaccatctg cagtagcatt ttctaatgaa gatgttatcg caccagcgaa
    52081 aatcttgaac gacttttcta aaaacgctga agcacttgaa attaaaggtg gtgcaatcga
    52141 aggcgctgtc gcatctaaag aagagattct tgcacttgca actcttccaa accgcgaagg
    52201 acttctttct atgctccttt ctgtacttca agcgccagtg cgcaacgttg ctcttgcagt
    52261 caaagcggtt gcagaaagca aagaagacgc ggcttaatct taagctacat agcgtagcct
    52321 agctacgaaa aaaactatta taaaatttaa aacttatttg gaggaaataa caatggcatt
    52381 gaacattgaa aacattattg ctgaaattaa agaagcttca atccttgaat tgaacgacct
    52441 tgtaaaagct atcgaagaag aatttggtgt aactgcagct gctcctgtag ctgttgctgc
    52501 agctgatgca actgatgctg gtgctgctaa agattcattc gacgttgaat tgacatctgc
    52561 aggcgacaaa aaagttggtg ttatcaaagt tgtacgtgaa atcactggtc ttggtcttaa
    52621 agaagctaaa gaacttgttg acggtgcacc agcacttgtt aaagaaggcg ttgcaactgc
    52681 agaagctgaa gaaatcaaag ctaaattgga agaagctgga gcttcagtta ctcttaaata
    52741 agaggcatat accaattaga aatcggaata ctatagtatc agccttttag aatcgtgaac
    52801 acattttaga aactgataaa ttaatttagt ttcctaccaa aaaccctacc aaaaattaat
    52861 ttggcagggt ttttcttttt aacaaattta tcgtggagaa caattgaata ttgttctcct
    52921 ttttttattt tcaggaggaa aaatgacaaa agaattacaa tcatcacgcc atattgtcat
    52981 ttcattttta gtacgtgaaa tgggaattga cattgttgag gccatctctc ttatggctga
    53041 attagaaaaa agtggcttgg ttcgcttgga atcaagtgga gatttaatac tcaaagaact
    53101 tggaggagcg ctatgaaacg aattaccgca aatcaatacc aaacttcaga acggtattat
    53161 aaattaccta aaattctttt tgaagatgag aaatatatgg atatgaaact agaagtaaag
    53221 gtggcttatt ctattttaaa agatcgttta gaattatctc tcagtcgtgg ttggatagat
    53281 gaagaaggag cggtttattt agtattttct aattctaaac tgatgaagct attaggttgt
    53341 tcgaagtcaa aattactgtc catcaaaaaa actcttaaag aatatgactt aattgatgaa
    53401 gttcaacagt cttcaagtga gaaggggaga ctagctaata agatttattt aggggaatta
    53461 tcttctaccc cagtaggtaa ttcaaacagg cctagtgtta aaaaaagact agggcaggat
    53521 gaaaatgata cggcccccgt ctcacattta gcccctagtg agactgaagt tagtgagact
    53581 aaatatagtg agactgattc tttatttatt gaggatgagg aggagaggaa tactcaacct
    53641 atcttgaaaa gaaaagtaga aaaggtcaca aaatatgatc gagattatat ttggggattg
    53701 gtacaagatc aatttagacg agaggggttt tctgaaacag ccagtgaaat tgctatgact
    53761 gattttgaga gaatctatca gtatgctctt gacaatgttc gctttgttag acgtgcggaa
    53821 gtacttgctg aatttgtgtt taatggcttg tattctgttt ggaacaaccg tgttagaaaa
    53881 ggaggtggtt aaatgtcgcc aatcgagtgg atattagtta tgctcattgt catttcaagt
    53941 ggagtgacag ttctgacaat gatagtcgat aagaaagggg tgataaagaa ttgagattta
    54001 ttgatttatt ttcaggtatc ggtggctttc gacttggaat ggaaagtgtt ggacacgagt
    54061 gtattggatt ttgtgagatc gataaatttg ctagagaatc ttataagtcc atttttcaaa
    54121 cggaaggaga aatagaattt catgacatac gagatgtttc agatgacgaa tttaaaaaac
    54181 ttagagggaa agtcgatgtc atctgtgggg gattcccttg tcaagcattt tcaatcgcag
    54241 gaagacgatt gggatttgaa gatactagag gaactttgtt ctttgaaatt gctcgggcgg
    54301 ccaaacaaat ccaaccacgt tttctttttc ttgaaaatgt taaaggccta ctcaatcacg
    54361 ataagggacg gacgttcacc acaatcctta ccacacttga tgagttgggg tttgatgttg
    54421 agtggcaggt gcttaacagt aaggattttg gcgttcccca aaacagagag agggtgttta
    54481 ttatcggaca ttctagaaag aaaggtaccc gactcctatt tcctttcaga cgagaaggtc
    54541 aagcaactaa ctctgagact ttgaaagcac taggaaattt gaatccatca aaaagtggaa
    54601 tgagtggtaa agtctattat tcagaaggtc ttgcgccaac cttagttcgt ggaaaaggag
    54661 aaggatttaa agttgcgatt ccttgtatga caccagacag attagaaaag agacaaaatg
    54721 gtagacgttt caaggataat caagagccaa tgtttacttt aaatactcag gatcgccatg
    54781 gtattgtcgt tgttggagat ttaccaacta gctttaagga aactggtcgc gtctatggaa
    54841 gtgaggggct atctccaaca ctgactacga tgcaaggtgg agataaaatc cccaaaatac
    54901 tgattccaga accaatccaa tttctaaaag tccgagaggc aacgaaaaaa ggatatgctc
    54961 aagcagagat tggggattca atcaatttag aaagaccaag ttctcagtat cgtcgtggta
    55021 gagttggaaa aggtatagcg aatacgttaa caactagtgg gcaaatggga gtagtagtgg
    55081 ctagctatga aggagaagat aaacaagttt accaagtagc tggtatctta attgatgggc
    55141 aattttaccg tttgaggata cgacgaatca ctcctaaaga gtgttttaga ctgcagggct
    55201 ttcctgattg ggcttttgaa gctgctagaa aagtctctag taatagtcag ctctataaac
    55261 aagctggtaa tagtgtaacc gttcctgtga ttgccgcaat cgcaaaaaaa ttaaaagaaa
    55321 tagaggaaaa agatgaaagc attaaataga gaatcaatac tagattgtga tgaattagaa
    55381 acagaattac atgacgcaga aatcaaacag ctggatgaac aaatattttt aatgcctaat
    55441 tatccatgtg agtttgaggt gacattttta gatgattacc ataaaaaaca taattaccca
    55501 ctattttatg aatcctatct tcaaaacatt atggaattcc ttgaaagtca ggatataaag
    55561 aacggagctg atgcctttgt agatgataat cagaatctag tttttgtttt atatggacaa
    55621 ggctatcgag ccgagggaaa agagggaata cttacaaccc aagtaactgt aaaagcttat
    55681 gatgaagaca agcaaccgat taacttcgca aatttattag attccttaat cgtatcagaa
    55741 tatcaaatgg aaccgaatct ttgggaggtt tcccatgatt gatctctatc taagtaaaaa
    55801 taaccataga aatcaacttc ttttggattt cttccaaaac tatggtatcg aggtatcttg
    55861 tcattcagtt tctgaaatga caaaggacaa attaattgag atgatgagct attcttcaga
    55921 ttgtttcgag tttttatctc ccaatttatt acgatttaag aaccgtgaca atttaagatt
    55981 aacggatttt attgaaatga tcttaaaaaa tcctgaacta accatcagac ttcctcttgc
    56041 ggtttcgaat aaaagagttt atccaaatct gaatctggag gaggctagag ctttattgcc
    56101 aagagatacg aaacaattga tttacatggc acaaacacat tatttatcta actaaaggag
    56161 aagcaatatg gctgaacgat tttgggagaa cttgtccatt attttggctg aaagaaatat
    56221 tagctggatt gagttaacca gaaaaatgtt tgcgggagag tttcactatc caagtgaatt
    56281 gaaccgtttg tatcaaaaga tacgccacta caagatggaa caacgaatgc ctcaaagtcc
    56341 atgggtagaa aggattgtgc aggtattaga tttagattat gaagatttat ttcggaggta
    56401 actatgaaaa gaatcattcc agtttatata ttccaacaag taaatgtcct attggtatct
    56461 ctatacttac tgaaattgct ttgtatcggt gagttaacta tactacagat tctctatggt
    56521 gcgtcactca tttctttttt atggatgtat ggccaacgca aacaagctca taaggtcaat
    56581 atgaaatcta ggatgaaatg gcttggtatt ggattcatta gcctactgat tataagtcta
    56641 tgttttagcc taatccatgc tcaaggaacc acgaatcaag caaacttaat tggacttcaa
    56701 catcaagttc cttggttttc atttttattg ttcttaatca atgcgagtat ggttgaagaa
    56761 tttctgtatc gagaaatttt atggaacttg gttagaaaat tagatattcg agttgctttg
    56821 acaagtgttt tatttgcctt agcacatcat ccaggaacca ttctagcttg gtgtttatat
    56881 gtttcacttg ggatgttttt agggcttgta cgctacaaat cggacttatg gggcagtatg
    56941 gggctacatt tggtgtggaa cctatcagtc tatgtcttat ttttgcttta ataatagctg
    57001 ttctgtctta cgtatggatt aattttgaaa taaaaatagc ataaaaatct agttatccgc
    57061 ataaaaactg gacttatcac actttatcaa ggtcaaaacc actcaattta ctactaattt
    57121 actacttatg aatgagcttt gatacgacga tttatccttg aaaagtgaag atataaagat
    57181 acttccaata aaatttgaat atttaatagg tagacacttc aaaaaatgag gtgtctattt
    57241 ttttacccga ttttgaaagg aagtgaactt atgaaaacaa aaaatcaaga atcaaaaggt
    57301 cgttccccac tctttaagac catcaaacat tcattcagcc aataaaaaag aaaggatagg
    57361 taaaaatatg gaacttaaat ttgtgattcc caacatggaa aaaacattcg gcaatttaga
    57421 atttgctggc gaggataaag tcgttcagcg aagaatcaac ggacggctaa ctgtcttatc
    57481 aagaagctat aatctctatt ctgatgttca aagagcagat gatattgtgg tggtgcttcc
    57541 tgctgaagct ggcgaaaaac atttcggctt tgaggaacgt gtgaagttag tcaatccacg
    57601 tattaccgca gagggctaca aaatcggcac tcgtggtttt acaaattacc ttttacatgc
    57661 tgacgacatg ataaaagaat aaagaaagag aggaaaaatg atgagattag caaatggcat
    57721 tgtattagat aaagacacga cttttggaga attgaaattc tctgctctac gtcgtgaagt
    57781 gagaatccaa aatgaagacg ggtcggtttc agatgaaatc aaggaacgta cctatgactt
    57841 aaaatccaaa ggacaaggac gcatgattca agtaagtatt cctgccagcg tgcctttgaa
    57901 agagtttgat tataacgcac gggtggaact tatcaatccc attgcggaca ccgttgctac
    57961 tgccacctat caaggagcag atgttgactg gtatatcaag gcagacgata ttgtgctgac
    58021 aaaggattct agttcattca aagctcaacc acaagcaaag aaagaaccga cacaagacaa
    58081 atagtcgcta ggtagaaagg agactttttc gcatgaaaca gcgtggtaaa aggattcgcc
    58141 catctggtaa agatttagtc tttcatttta cgatagcgtc actcctgcct gttttcctgc
    58201 tggttgtcgg actgtttcat gtgaagacaa tccagcagat caactggcag gattttaacc
    58261 tatcacaagc agataagatt gacattccct atttaattat cagtttcagt gtcgcaattc
    58321 ttatctgctt gctggtagcg tttgtattca aacgggttcg ctatgatacg gttaaacaac
    58381 tttaccaccg tcaaaaactg gcaaagatga tacttgaaaa caagtggtat gaatctgaac
    58441 aggtcaaaac agagggtttc tttaaagata gtgctggtcg tacaaaaaag ataacctact
    58501 tccctaaaat gtattatcga cttaaaaatg gcttgataca gatacgggtg gaaatcacgc
    58561 tgggaaaata tcaagaccaa ctcttacact tggaaaagaa attagagagt ggcttgtact
    58621 gtgagctgac ggataaagag ttaaaggatt cctatgtgga atatactttg ctctatgaca
    58681 ccatagccag tcgtatttct attgatgaag tagaagctaa agatggtaaa cttcgcttaa
    58741 tgaaaaacgt atggtgggaa tatgataagc tccctcatat gttgattgct ggtggtacag
    58801 gtggcggtaa aacttacttt atactgacac tgattgaagc cttgcttcat acagattcaa
    58861 aactgtatat tcttgacccg aaaaatgctg accttgcgga cttaggttct gtgatggcaa
    58921 atgtctacta tagaaaagaa gacttgcttt cttgcattga aacattctat gaagaaatga
    58981 tgaaacgtag tgaggaaatg aagcagatga agaactataa gactggcaaa aattatgctt
    59041 acttaggtct cccggcacac ttcttaatct ttgatgaata cgtcgctttc atggaaatgc
    59101 tgggaacaaa agaaaacacc gcagttatga ataagctgaa acagattgtc atgttaggtc
    59161 gtcaagctgg cttctttcta atactggctt gtcaacgtcc agacgcaaaa tatttaggcg
    59221 acggaatccg tgatcagttt aatttcagag tggctttagg tcgtatgtct gaaatgggct
    59281 atggcatgat gtttggcagt gacgtacaaa aggatttctt cttaaagcga atcaaaggtc
    59341 gtggctatgt tgatgtagga acaagtgtca tatcagagtt ttatactccc cttgtaccaa
    59401 aaggatatga tttcttggag gaaattaaaa agttatccaa cagcagacag tccacgcagg
    59461 cgacgtgcga agcggaagtc gcaggtgtgg actgatcttg ctggctggtg tggcaatagc
    59521 cacgccagca cttaaccccc cgtatctaac aggggggtac aaatcgacag gaaacagtca
    59581 aaaaaacatt agaaaatcct ttggttacaa gggatttaca aaatttcagc gtatgtcaaa
    59641 tgggctttaa aagttgacat acgccttttt gattggaggg atttttactg aatgaacaaa
    59701 cttggttaca gcatttaaaa gaaaaacgct tggcttatgg actatctcaa aaccgtttag
    59761 ctgttgcgac tggtattaca aggcagtatc taagcgatat tgaaacagga aaagtcaagc
    59821 catcagagga tttacagcag tccctttggg aagctctgga acgcttcaat cccgacgctc
    59881 cccttgaaat gctgtttgat tatgtaagaa ttcgctttcc gacaacagac gtacagcagg
    59941 tggtcgaaaa catcttacaa ctgaaactgt cctattttct tcatgaggac tatggtttct
    60001 attcttattc agagcattat gctttaggcg acatattcgt cctttgctcc catgaactgg
    60061 acaaaggagt tctggtggaa ttgaaaggtc gtgggtgcag acaatttgaa agctatcttc
    60121 tggcacaaca aagaagctgg tatgagttct ttatggacgt tttggtggct ggcggtgtga
    60181 tgaaacgcct tgaccttgcc attaacgata agacagggat tttgaatatc cctgtactca
    60241 ctgaaaaatg cagacaggaa gaatgtatat ccgtcttccg cagtttcaaa agctatcgca
    60301 gtggcgaact ggtacgcaaa gatgaaaagg aatgtatggg aaataccctc tatatcggtt
    60361 cattacagag tgaagtttat ttctgtatct atgaaaagga ctatgaacag tacaagaaaa
    60421 atgatattcc cattgaagac gcagaagtaa aaaaccgttt tgagattcgg ctgaaaaatg
    60481 agcgtgccta ttatgcagtc cgtgatttac tcgtctatga caatccagag cataccgcct
    60541 ttaaaattat caatcggtat atccgttttg tagataaaga cgattccaaa cctcgttctg
    60601 attggaaact gaatgaagaa tgggcttggt ttattgggaa caatcgtgaa cgattaaaac
    60661 taaccacaaa accagagcct tactccttcc aaaggacgct gaactggcta tctcatcaag
    60721 ttgccccgac cttaaaggtt gcgattaaac ttgatgaaat caaccagacg caggttgtaa
    60781 aagacattct cgaccatgcg aaactgacag accgacacaa gcagattttg aagcaacagt
    60841 cagtaaaaga acaggacgtg ataacaacaa aaaaaggata tctgtcaacc ataccagttg
    60901 acagatatcc aaaaaaagat ataatgggag ataagacggt tcgtgttcgt gctgacttgc
    60961 accatatcat aaaaatcgaa acagcaaaga atggcggaaa cgtaaaagaa gttatggaaa
    61021 taagacttag aagcaaactt aagagtgtgt tgatagtgca ttatcttaaa attttgtata
    61081 ataggagtgg tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca
    61141 actttgaaaa agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg
    61201 agttcgtctt gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag
    61261 gaaataataa atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata
    61321 ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga
    61381 aaatgaaaac ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt
    61441 ggaacgggaa aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct
    61501 gcactttgaa cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct
    61561 ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga
    61621 gtgcatcagg ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga
    61681 cagccgctta gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga
    61741 aaactgggaa gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac
    61801 ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt
    61861 tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa
    61921 gtggtatgac attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta
    61981 tgtcgagcta ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta
    62041 tattttactg gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac
    62101 aagcttttta gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt
    62161 tttatatctt ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt
    62221 ggtgaagagg tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc
    62281 agctagctta agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat
    62341 ttgaacagga ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaaataatt
    62401 cctgccaaag aaattgcaca gcgatttaat ataagcttaa ggacagttta cagagatatc
    62461 cggacacttg aagaagccgg aataccaatt ggatctgagg ccggaaaagg atattttctt
    62521 gtagagggct tcctacttcc gccggtaatg tttacagcgg cggaagtggg tgcattgatt
    62581 acagcaggga aatttttaaa ttgccatgga gatgaatcat ttataaagga ttttgattca
    62641 gctatgtata aaatcaaatc tattttgaag catggtgaaa aaaactatgc acaggagttg
    62701 gagaacagta ttaacgtgta cagcacatct ggacagaaaa atacattggc ggataacgtt
    62761 attgcagcaa ttcagactgc aatctgcaat aaaagggtaa tattaattca atatcctgca
    62821 tcaggagggc aagaaccgga aagcagaatg atagagccta tatcactggg gttttatgaa
    62881 cagaactggt acttaatcgg ttttgcaggc taagaaatga atataggaat tttcgtgtgg
    62941 atcggattaa aagcatttgc atagaagaag agctctgtca aagccatgat ggctctttgg
    63001 aacaaatatt aaaacaaatg ctttcatata aaaaactata tgccctacaa tgccgttgta
    63061 aaaattgggg aaaagggata tattgatttt atatctttct caaaataaac ataaaagccc
    63121 tttaaagagg gcttttatat attaatcaca aatcacttat cacaaatcac ttatcacaaa
    63181 tcacaagtga tttgtgattg ttgatgataa aataagaata agaagaaata gaaagaagtg
    63241 agtgattgtg ggaaatttag gcgcacaaaa agaaaaacga aatgatacac caatcagtgc
    63301 aaaaaaagat ataatgggag ataagacggt tcgtgttcgt gctgacttgc accatatcat
    63361 aaaaatcgaa acagcaaaga atggcggaaa cgtaaaagaa gttatggaaa taagacttag
    63421 aagcaaactt aagagtgtgt tgatagtgca gtatcttaaa attttgtgta taataggaat
    63481 tgaagttaaa ttagatgcta aaaatttgta attaagaagg agggattcgt catgttggta
    63541 ttccaaatgc gtaatgtaga taaaacatct actgttttga aacagactaa aaacagtgat
    63601 tacgcagata aataaatacg ttagattaat tcctaccagt gactaatctt atgacttttt
    63661 aaacagataa ctaaaattac aaacaaatcg tttaacttct gtatttgttt atagatgtaa
    63721 tcacttcagg agagattaca tgaacaaaaa tataaaatat tctcaaaact ttttaacgag
    63781 tgaaaaagta ctcaaccaaa taataaaaca attgaattta aaagaaaccg ataccgttta
    63841 cgaaattgga acaggtaaag ggcatttaac gacgaaactg gctaaaataa gtaaacaggt
    63901 aacgtctatt gaattagaca gtcatctatt caacttatcg tcagaaaaat taaaactgaa
    63961 tactcgtgtc actttaattc accaagatat tctacagttt caattcccta acaaacagag
    64021 gtataaaatt gttgggaata ttccttacca tttaagcaca caaattatta aaaaagtggt
    64081 ttttgaaagc cgtgcgtctg acatctatct gattgttgaa gaaggattct acaagcgtac
    64141 cttggatatt caccgaacac tagggttgct cttgcacact caagtctcga ttcagcaatt
    64201 gcttaagctg ccagcggaat gctttcatcc taaaccaaaa gtaaacagtg tcttaataaa
    64261 acttacccgc cataccacag atgttccaga taaatattgg aagctatata cgtactttgt
    64321 ttcaaaatgg gtcaatcgag aatatcgtca actgtttact aaaaatcagt ttcatcaagc
    64381 aatgaaacac gccaaagtaa acaatttaag taccattact tatgagcaag tattgtctat
    64441 ttttaatagt tatctattat ttaacgggag gaaataattc tatgagtcgc ttttttaaat
    64501 ttggaaagtt acacgttact aaagggaatg gagataaatt attagatata ctactgacag
    64561 cttccaagaa gctaaagagg tccctagcgc ctacggggaa tttgtatcga taaggggtac
    64621 aaattcccac taagcgctcg ggaccccttg taggaaaatg tcctaagtgg gatatctgtc
    64681 aactggtatg gttgactaaa aatacttcct acgaaaatgt agggggtatt tttttacgaa
    64741 aaaatacaat cgattcttaa aaagaaaaat ttttgattgg caaaaccata acaagttcgt
    64801 tttagggttt tgattttgcg attgatgcct tctaaaggac cattagagta ttcaaattta
    64861 gcgctattta agacatattt tctgttttga cgaagggttt gaatagcagt atccatttct
    64921 gtattggttt tttggtagtc taagatggtt gactctagta attcactatt gcgctcgttt
    64981 agggctttcg tgatatcttg gtaagtttgg tatacttcag cgaacttgga aaatttacta
    65041 gtaatgagat caacagcatt ttggcgagtc atatattgtt taacgccgcg aagaaaaact
    65101 acttcttcag ggtgaagatc ttcagctttt ttatggaata gcttccaatg tgacttcata
    65161 attttatatt cttggctctg tttatcaagt tgctttagga tagagatacg acaattgtcc
    65221 aaagcgcgac cagctaattg tacaaggtgg aagcgatcaa taatgatatt ggcattaggg
    65281 aaaaggcgat agataaaact ttgatattga gcatttaaat caattacaac tgattgaacg
    65341 cattcgcgtt cggcttttga ataacgactt tcaaaataat caacaatggt aggtgataga
    65401 cgatcctgta actttgtgac aatttggtgg gtttcagcgt cacaacagat aaaggacatc
    65461 acagacttaa ttgaacgaaa ctcgtcaaaa catagatgct taggcaactt agccacacga
    65521 tagtgtggtt ccatgcgctc taagattgtt cgacgaacac tgctaggaga gcagtgacac
    65581 atttcagcaa taagctgacc agataagcct ttacgagcta aaagcatgat ttgatttttg
    65641 agatcactgg ataaggtttg attttctttg gttaaattag taatagcacc aaaagtagta
    65701 tggcatgatt tacatttata gcgttgttta cgaagctcta gttcatatct tctcccattt
    65761 aaacttgcca gtcgtacatg agttttgcga aagccatcct tattaactgt gggaaagcca
    65821 cagttacgac aacgattaat cggataagaa agagtagctg ttattagcgt tatatactct
    65881 ttaacagaat cgttgttgtg ttcagcttct tcaacagaaa taattttaat atttttatct
    65941 ttaattccaa gaatatttag gatagaatca ttatgggaca tttgtttaac cttctttcat
    66001 gatttttgtg gtgaattgat tgtataacga ggggacagca aatgtcctct tttttgtata
    66061 aaaaaatctg gcatggaatc tctatccata ccagaaagtg tataccccaa aaaaataact
    66121 caaatacaaa ttcattgaat atagagagga gaacattttt atgaattttg gacaaaacct
    66181 ttataactgg tttctatcaa acgctcaatc actggtgctt ttagcaatcg ttgtgattgg
    66241 cttgtatctt ggcttcaagc gtgagtttag caaactgatt ggctttttaa ttattgcgat
    66301 tattgcggtt ggcttagtct tcaacgctgc tggagtaaaa gacattttac tagagctatt
    66361 caatcgcatt attggtgctt aaataaaacc gttcttttgt ggaatataag tggttttctt
    66421 atgttccgca aaggaatggt acaccaaacg aagtgcggta gggatttttg aatctctaca
    66481 aagaaaggac gtgaatatat ggacgatatg caagtctata ttgcgaattt aggcaaatac
    66541 aatgagggcg aattggtcgg tgcgtggttt acctttccca ttgactttga ggaagtcaaa
    66601 gagaaaatcg gcttgaatga tgaatatgag gaatacgcca ttcatgacta cgagttaccc
    66661 tttacggttg acgaatacac ttccattggc gaactcaatc gactatggga aatggtatcg
    66721 gaattacccg aagaattaca atcggagcta tctgctctgc tcactcattt ttcaagcatt
    66781 gaagaactaa gcgaacatca agaggatatt atcattcatt ccgattgtga tgatatgtat
    66841 gacgtggcac gctactacat tgaagaaacg ggtgctttag gcgaagtacc agctagtctt
    66901 caaaactata ttgattatca agcctatggt cgggatttag acctttcagg aacgtttatc
    66961 tcaaccaatc atgggatttt tgaaatcgtc tattaaatct gtcggtacat tactactggc
    67021 agattttcta ttttacgggg tggctcaatc agctacccct attttttatg aaaggattga
    67081 ttacatgaag aaaatacgaa gctataccag tatctggtct gtggaaaagg tactgtattc
    67141 tatcaatgat tttagacttc cgtttcccat aacctttacg caaatgacat ggtttgtcgt
    67201 gtcactcttt gcagtgatga tacttggcaa cttgccccct ctttccatga tagagggagc
    67261 atttctcaaa tactttggga ttcctgtggc tttcacatgg tttatgtcta caaaaacttt
    67321 tgatggtaaa aagccttatg gatttttgaa gtctgtcatt gcttatgcac tgcgaccaaa
    67381 gctgacctat gcaggaaaaa aagtaacgct tggcagaaac cagccacaag aagccattac
    67441 agcagttagg agtgaatttt atggcatatc caattaaata cattgaaaac aatctcgtct
    67501 ggaataaaga cggggaatgt tatgcttact atgagcttgt tccttacaat tactcatttc
    67561 taagtccaga acagaaaata caagtgcatg attctttcag acagcttatc gcacaaaatc
    67621 gtgatggcaa aattcatgct ttacaaatca gtacagaatc cagcatacgt tctgcacaag
    67681 agcgttccaa aaatgaagtc actggcaagc tcaaagcggt tgcctatgac aaaatcgacc
    67741 aacagacaga cgctttaata tccatgattg gcgaaaatca agtggactac cgtttcttta
    67801 tcggttttaa gttgcttctc aacgatcagg agttttctat gaaaagtctt accgttgaag
    67861 caaaaaatgc ttttactgat tttgtctatg atgtgaacca taagctgatg ggcgattttg
    67921 ttagtatgag taatgatgaa atcctgcgtt ttcagaagat ggaaaagctt ttagaaaata
    67981 aaatctcccg tcgtttcaaa atccgaagat tagataagga cgacttcggc tatctgattg
    68041 aacaccttta cggacagaca ggcactgcct atgaagagta tgagtaccat ctatcaaaga
    68101 aaaagctgga taatgaaacg ctgattaaat actatgactt gattaagcct actcgctgtc
    68161 tggtggaaga aaaacagcga tatttgaaaa tccagcagga agatgaaacc gtctatgtag
    68221 cttactttac cattaacagc attgtcggag aactggactt cccgtcctct gaaatcttct
    68281 actaccagca acagcaattt acattcccga ttgatacgtc aatgaatgtg gaaattgtag
    68341 cgaatcgtaa agccctatct actgtccgca ataaaaagaa agaactgaaa gacttggata
    68401 accacgcttg gcaaagtgat aatgaaacca gctccaatgt ggcggaagct ctggaaagtg
    68461 tgaatgagct ggaaaccaat ttagaccaaa gcaaggaatc tatgtacaag ctgtcttatg
    68521 tggtaagggt atcagcaaat gatcttgacg aactcaaacg tcgttgtaat gaagtgaaag
    68581 atttttatga cgatttaagc gtaaaactgg tacgaccatt tggggatatg ctcggcttac
    68641 atgaagaatt tttacctgcc agcaagcgtt atatgaatga ttatattcaa tacgtgacct
    68701 ctgatttcct cgctggttta ggttttggtg ctactcaaat gctgggggaa aatgagggga
    68761 tttatgttgg ctacagctta gatactggac gcaatgtcta tctgaaacct gctcttgcca
    68821 gtcaaggggt taagggttca gtaaccaatg cgttagcgtc ggcttttgtt ggttcgctgg
    68881 gtggtggtaa atcctttgcg aataacctta tcgtctatta tgcggtgctt tatggggcac
    68941 aagcagtgat tgtagaccca aaagcagaac gtggcagatg gaaagaaacc ttgccagaga
    69001 tttcccatga aatcaatatc gtcactctga cttctgatga gaaaaacaaa ggcttacttg
    69061 acccttatgt gattatgaaa aatcccaaag attctgaatc actggctatt gatattctga
    69121 cattccttac ggggatttcc tctcgtgatg gggaacgctt cccaatcctt agaaaagcca
    69181 ttcgtgcagt aaccaatagt gaagtacgag ggttgatgaa agtgattgag gaattacggg
    69241 ttgagaatac gccactaagt accagtatag ccgaccatat cgaaagtttt acagactatg
    69301 actttgcaca tttattattc agtaatggtt atgtggagca gtctatcagc ttagaaaaac
    69361 aactgaacat tatacaggtt gcggacttgg tacttcccga caaggaaact tcctttgagg
    69421 aatataccac tatggagctt ttatccgttg ctatgctgat tgtcattagt acctttgctt
    69481 tagactttat ccatacagac cgaagcattt tcaagattgt agatttagac gaagcatgga
    69541 gctttttaca ggtagcacaa ggaaaaacac tatctatgaa gctggttcgg gctggtcgtg
    69601 ctatgaacgc tggggtatat ttcgtgaccc aaaatacaga cgacctctta gatgaaaaac
    69661 tgaaaaataa cctcggctta aaatttgcat ttcgttccac tgaccttaac gagattaaaa
    69721 agaccttagc cttttttggt gtagacccag aggacgaaaa caatcagaag cgattgcgtg
    69781 atttggaaaa cgggcaatgc cttatcagtg atttatatgg tcgtgtcggt gtgatacagt
    69841 tccaccctgt atttgaagaa ctgctccatg cctttgatac cagaccacct gtgcgaaaag
    69901 aggtgtaaat gtgaaaccat caatagtaaa cagaataaaa tcaaactgga cgctgaaacg
    69961 tctaggtaaa gtggcaatga cagtggcttt cacacttgtg attgccattt ttcttttagc
    70021 catgctggga acggtggttc aagctgcggg cttggtagat gatacggtca atgtggcaaa
    70081 tgaatacagc cgatacccac ttgaaaacta tcaactggat ttttatgtgg ataatagctg
    70141 gggctggctt ccgtggaact ggtcggacgg gattggaaaa caggtcatgt atggactata
    70201 tgccattacc aattttattt ggacaatcag tttgtatgtt tccaatgcga caggttactt
    70261 agtacaggaa gcctattcct tagacttcat ttccgctaca gcagattcca ttggtaagaa
    70321 tatgcagacc ttagctggtg tgagtgcaaa cggattttca acagagggtt tctatgttgg
    70381 attcctctta ctcttgattt tggttcttgg ggtttatgtt gcctatacgg gactgataaa
    70441 gagagaaacc acaaaggcaa ttcatgccat tatgaatttt gtgctggtgt ttatcctatc
    70501 ggcttccttt attgcctacg ctcccgacta cattaaaaaa atcaatgact tttcatcaga
    70561 catcagtaat gccagtttat cacttggcac gaagattgtc atgccccatt ccgatagtca
    70621 aggcaaggac agcgtggact taatcagaga tagcctgttt tccatacagg ttcagcaacc
    70681 gtggctactg cttcaataca acagttcaga cattgaaagt atcggtattg accgtgtgga
    70741 aagcctgctc tccaccagcc cagattccaa caatggcgaa gacagagaaa aaattgttgc
    70801 ggaagaaatt gaagacagaa gcaataccaa tctaaccatt acaaagacca ttaaccgttt
    70861 aggtacagtc ttcttcctat ttgtcttcaa tattgggatt tccatatttg tattcctatt
    70921 aacaggaatc atgattttct cgcaggtact ttttatcatc tatgctatgt ttctgcctgt
    70981 gagctttatt ttaagcatga ttccatcatt tgatggtatg tcaaaacgag ccataacaaa
    71041 gctctttaat accattttga cacgagctgg aatcacattg attattacga cagcatttag
    71101 tatttcaacc atgctctata ccttatcggc tggttatccg ttctttttga ttgcttttct
    71161 acagattgtg acctttgcag gaatctactt caagctgggc gatttaatga gtatgttttc
    71221 tctacagagt aacgattctc aaagtgtggg aagtcgtgtg atgagaaaac ctcgtatgct
    71281 tatgcacgct cacatgcacc gtctacagcg gaaacttgga cgttccatga ctactctagg
    71341 ggctgggtct gccattgtta caggtaaaaa aggacagtcg ggttcgggga gttctgcaag
    71401 gacacaagca gatcactccc gaccagacgg aaaggaaaaa tcaacacttg gaaaacgtat
    71461 cggtcaaacc atcggtacag tagctgatac caaagacaga atggtagaca ctgctagtgg
    71521 tttgaaagaa caggttaaag atttgccgac caatgcaaga tatgcagtat atcaaggaaa
    71581 atccaaagta aaagagaatg tccgtgattt aaccagtagt atttctcaaa ccaaagcgga
    71641 cagagccagt ggacgcaagg aacagcagga acaaaggcga aaaaccattg cgaagcgtcg
    71701 ctctgaaatg gaacaggtca aacagaaaaa acagcctgct tcttctgttc atgaaagacc
    71761 gactacaaga caagaacaat atcatgatga acagacctca aaacagtcta atattcagac
    71821 ttcatataag gaatctcaac aagccaaaca agagcgtcca gcagttaagt ccgatttttc
    71881 aagtccaaaa gtggaacgcc aaggcaatac cgttcaagaa aaaaccgttc aaaagccagc
    71941 aacttcaacc actacagcag atagaacttc acaacgtcca atcacaaaag aacgtccgtc
    72001 tactgttcaa agagtaccac tacaaaatac aagaagtaga ccaccaatca aaaccgccac
    72061 cattaagaaa gtcggtaaga aaccatgaag ttgaaaactt tagtgattgg tggttctgga
    72121 ttattcttga tggtcttctc actgcttctg tttgttgcca ttttattttc agatgaacag
    72181 gacagcggaa tttccaatat tcattatgga ggtgtgaatg tttccgcaga agtgctggct
    72241 cataagccta tggtagaaaa atatgccaaa gaatatggcg ttgaagaata tgtcaacata
    72301 cttcttgcga ttatacaggt ggaatcgggc ggtactgcgg aagatgttat gcagtcctcg
    72361 gaatccctcg gtcttccacc taattcattg agtacagaag aatccattaa gcaaggtgtg
    72421 aagtatttca gtgaattatt agccagtagc gaaaggctca gtgtagattt agaatcggtt
    72481 atccagtcct acaattatgg tggtggtttc ttagggtatg tggctaatcg tggaaataaa
    72541 tatacctttg aactggctca aagtttctca aaagagtatt caggtggcga aaaagtgtct
    72601 taccccaatc ccatagccat acctatcaat gggggctggc gatacaacta tggcaatatg
    72661 ttttatgtgc aactggtaac gcagtatctt gtcacaacag agtttgatga tgatacggta
    72721 caagccatca tggacgaagc actgaaatat gagggctggc gatacgttta cggtggagct
    72781 tccccgacta cttcttttga ttgtagcgga ctgacacaat ggacgtatgg aaaagctgga
    72841 attaacttac cacgaaccgc acaacagcaa tatgatgtga cccagcatat cccactatcg
    72901 gaagcacaag ctggcgattt ggttttcttt cattctacct ataacgctgg ctcttatatt
    72961 actcatgttg ggatatacct tggcaataac cgtatgtttc atgcaggcga cccaatcggt
    73021 tatgccgact taacaagccc ctactggcaa cagcatttag tgggagcagg acgaatcaaa
    73081 caatgagaaa ggaagattta atgatgaaat ttagaaaaaa tcagaataaa gaaaaacaga
    73141 taccaaagga aaagaaacct cgtgtctact ataaggtcaa tcctcataaa aaggttgtga
    73201 ttgccttgtg ggtactttta gggcttagtt tcagctttgc gatattcaag cactttacag
    73261 ctatagatac tcatactatt cacgaaacaa ctatcataga aaaggaatac gttgatactc
    73321 atcatgtaga aaattttgta gagaactttg cgaaagtcta ctattcatgg gagcaatccg
    73381 ataagtccat tgataatcga atggaaagtc taaaaggcta tctgacagat gaacttcaag
    73441 ctctcaatgt tgatacagta cgcaaagata ttcctgtatc gtcttctgta agaggatttc
    73501 agatatggac ggtagagcca actggcgaca atgagtttaa tgtaacctac agtgtagacc
    73561 agctcattac agagggagaa aatacaaaga ccgtccactc tgcttatata gtgagtgtct
    73621 atgtagatgg ttctggaaat atggtactgg ttaagaatcc gaccattacc aacataccta
    73681 agaaatcaag ttataaacca aaagccattg aaagtgaggg gacggttgat tccattacaa
    73741 ccaatgaaat caatgagttt ttaacgacgt tcttcaagct ctatcctaca gcgacagcca
    73801 gtgaactttc ctactatgtg aatgacggga tattaaaacc aatcggaaaa gagtacatct
    73861 ttcaagaact ggtaaatcct attcacaatc gtaaggataa tcaagtcacg gtatcgctga
    73921 cagtggagta tatcgaccag cagaccaaag caacgcaggt atctcaattt gatttggtac
    73981 ttgaaaagaa cgggagtaat tggaagattg taaaataaca aatattggta catgattaca
    74041 gatactttgt aatcatgtac tctttttgat aaaaaattgg agattccttt acaaatatgc
    74101 tcttatgtgc tattatttaa gtgactattt aaaaggagtt aataaatatg cggcaaggta
    74161 ttcttaaata aactgtcaat ttgatagcgg aaacaaataa ttagatgtcc ttttttagga
    74221 gggcttagtt ttttgtaccc agtttaagaa tacctttatc atgtgattct aaagtatcca
    74281 gagaatatct gtatgctttg tatacctatg gttatgcata aaaatcccag tgataaaagt
    74341 atttatcact gggattttta tgcccttttg ggtttttgaa tggaggaaaa tcacatgaaa
    74401 attattaata ttggagtttt agctcatgtt gatgcaggaa aaactacctt aacagaaagc
    74461 ttattatata acagtggagc gattacagaa ttaggaagcg tggacaaagg tacaacgagg
    74521 acggataata cgcttttaga acgtcagaga ggaattacaa ttcagacagg aataacctct
    74581 tttcagtggg aaaatacgaa ggtgaacatc atagacacgc caggacatat ggatttctta
    74641 gcagaagtat atcgttcatt atcagtttta gatggggcaa ttctactgat ttctgcaaaa
    74701 gatggcgtac aagcacaaac tcgtatatta tttcatgcac ttaggaaaat ggggattccc
    74761 acaatctttt ttatcaataa gattgaccaa aatggaattg atttatcaac ggtttatcag
    74821 gatattaaag agaaactttc tgccgaaatt gtaatcaaac agaaggtaga actgtatcct
    74881 aatatgtgtg tgacgaactt taccgaatct gaacaatggg atacggtaat agagggaaac
    74941 gatgaccttt tagagaaata tatgtccggt aaatcattag aagcattgga actcgaacaa
    75001 gaggaaagca taagatttca taattgttcc ctgttccctg tttatcacgg aagtgcaaaa
    75061 aacaatatag ggattgataa ccttatagaa gtgattacga ataaatttta ttcatcaaca
    75121 catcgaggtc cgtctgaact ttgcggaaat gttttcaaaa ttgagtattc ggaaaaaaga
    75181 cagcgtcttg catatatacg tctttatagt ggcgtactgc atttgcgaga ttcggttaga
    75241 atatcggaaa aggaaaaaat aaaaattaca gaaatgtata cttcaataaa tggtgaatta
    75301 tgtaaaatcg ataaggctta ttccggggaa attgttattt tgcagaatga gtttttgaag
    75361 ttaaatagtg ttcttggaga tacaaagcta ttgccacaga gagagagaat tgaaaatccc
    75421 ctccctctgc tgcaaacgac tgttgaaccg agcaaacctc aacaaaggga aatgttactt
    75481 gatgcacttt tagaaatctc cgacagtgac ccgcttctgc gatattatgt ggattctgcg
    75541 acacatgaaa tcatactttc tttcttaggg aaagtacaaa tggaagtgac ttgtgctctg
    75601 ctgcaagaaa agtatcatgt ggagatagaa ataaaagagc ctacagtcat ttatatggaa
    75661 agaccgttaa aaaaagcaga gtataccatt cacatcgaag ttccaccgaa tcctttctgg
    75721 gcttccattg gtctatctgt agcacagctt ccattaggga gcggagtaca gtatgagagc
    75781 tcggtttctc ttggatactt aaatcaatcg tttcaaaatg cagttatgga ggggatacgc
    75841 tatggctgtg aacaaggatt gtatggttgg aatgtgacgg actgtaaaat ctgttttaag
    75901 tatggcttat actatagccc tgttagtacc ccagcagatt ttcggatgct tgctcctatt
    75961 gtattggaac aagtcttaaa aaaagctgga acagaattgt tagagccata tcttagtttt
    76021 aaaatttatg cgccacagga atatctttca cgagcataca acgatgctcc taaatattgt
    76081 gcgaacatcg tagacactca attgaaaaat aatgaggtca ttcttagtgg agaaatccct
    76141 gctcggtgta ttcaagaata tcgtagtgat ttaactttct ttacaaatgg acgtagtgtt
    76201 tgtttaacag agttaaaagg gtaccatgtt actaccggtg aacctgtttg ccagccccgt
    76261 cgtccaaata gtcggataga taaagtacga tatatgttca ataaaataac ttagtgtatt
    76321 ttatgttgtt atataaatat ggtttcttgt taaataagat gaaatatttt ttaataaaga
    76381 tttgaattaa agtgtaaagg aggagatagt tattataaac tacaagtgga tattgtgtcc
    76441 tgtatgtgga aataaaacac gattaaagat aagggaagat actgaattaa aaaaattccc
    76501 cctctattgt ccgaaatgca gacaagaaaa tttaattgaa ataaagcagt tcaaagtaac
    76561 tgtgattaca gagccagacg caaagacgca gagccgataa aatgagatta atacaatctc
    76621 attttatcgg ctctttccgt tatgtatgga ttcttttaat tagtcttcga tgtttcttgc
    76681 ttcgttgata ccgctggcta aagattccat taaggatagt tctttgtctg taaagctatc
    76741 catgtatttc tctatctgta atcgtcgggt gctttttacc aagttattag caggtaagaa
    76801 aaattcatca acggaaacat gaagtaacga tacaaggtca taaagaactt gtatgctggg
    76861 gtgttgccct ttattttcaa tattagttaa gtaccgtggg tcaatttcaa tcaatgctcc
    76921 cacttgttca cgagttaaac ctcgtttcaa tcgagcttct ttaatggcta aaccaaaggc
    76981 tctaaaatca tatttatctt cttttttacg catagtagac cacctctata cattttattg
    77041 tccctactga attaaaaaca ggtatagaaa aacgtgttat atggtttata ggtttatatt
    77101 taataaaaag cactactaaa cgccaataaa aaaaaccgtt atatggtagt gctatttacg
    77161 ctgttaaaat attgtatatt acttccaaat ggcggtttgt tggaggtcaa cgtcgccatg
    77221 aagtacatca tatacaataa atttccttac attgggttct tgtcaaaaaa agtcgtctat
    77281 ctgcaataga taagtacgtc caccaatgtg gttttataaa tcatatagat agaataacag
    77341 aagcatgtaa acagagaaat aaatctgttt atatgctttt ttggctattc agaacttttt
    77401 tacaaagttt atttatcagt aatgcaacaa atcccccttt cacattggga ctaagagtga
    77461 aaggagataa acgagcaagg ctcacttcct ttcctagaca gaaagggggt gagaaacatg
    77521 aaaccatctt cttttcagac cacaatagaa aatcagtttg actatatctg taaacgtgct
    77581 atggaagacg agcgaaagaa ttatatgctt tatctttcaa ggattgcaaa gcgtgaggtg
    77641 tccttttcgg atgttggcga ttatcttgtt agccagtttg cgacaacaga taactattca
    77701 actgactttc agatttttac actcaatggg ttatcagtag gcgttgaaaa tgatttgttg
    77761 agtgaagcat tacgtgagtt gccagacaag aaacgtgaaa ttctactgct gttttacttt
    77821 atggacatga gcgattcaga aattgcagac ctgttgaaat tgaaccgttc tactgtctat
    77881 cggcatagaa ccagtggact agccttaatt aaaaagttta tggaggaatt tgaagaatga
    77941 aaacacaata tcctatgatt ccctttcctc tcattgtaaa ggcaacagat ggcgataccg
    78001 aagcgattaa ccagattcta catcattaca gagggtacat aacgaagcgt tccctacgac
    78061 ttatgaaaga tgaatatggc aatcaaagta tggtcgttga tgaagtctta cgtggaagaa
    78121 tggaaaccag actgattaca aagattttgt catttgaaat taagtaatat cctctctcct
    78181 ttcgtggaag cgtgctaaac cattccacgc ttcccgaaca gggaggtttg ttattccacc
    78241 aaagcatatt gagctttcaa tgtgttttga taggctaacg agccattgtt ctttgaaaac
    78301 tgaataaaag taatcgaata cgtttcgata agaaaagagc caacggaact aaccgccatg
    78361 acctatctta taaagatagc gagcgattca tgttagtgat ccgagaagca atctttagca
    78421 ggattgcctg caacgacatt cttatcgtga taatgatact cccatacagt caatagtccg
    78481 agcgtgataa aaccgtcgca ggcaatgagt atggctacat gagaaccatg caggggtgga
    78541 actcccgtga gctttgctaa agctgttcga ttgctggtaa aacaactttt atgaaatcca
    78601 aataagtgat ttggaaagga ggattttatg aagcagactg acattcctat ttgggaacgt
    78661 tataccctaa ccattgaaga agcgtcaaaa tattttcgta ttggcgaaaa caagctacga
    78721 cgcttggcag aggaaaataa aaatgcaaat tggctgatta tgaatggcaa tcgtattcag
    78781 attaaacgaa aacaatttga aaaaattata gatacattgg acgcaatcta gcgtcgccaa
    78841 agggtcttgt atatgataaa atagtattaa gtcgtatcaa ggctctttcc ataaaggaaa
    78901 ggagcaaatg ccatgtcaga aaaaagacgt gacaataaag gtcgaatctt aaagactgga
    78961 gagagccaac gaaaagacgg aagatactta tacaaatata tagattcatt tggagaaccg
    79021 caatttgttt actcgtggaa acttgtggct acagaccgag taccagcagg aaagcgtgat
    79081 tgtatctcac ttagagagaa aatcgcagag ttacagaaag acattcatga tggtattgat
    79141 gttgtaggaa agaaaatgac actctgccag ctttacgcaa aacagaacgc tcaaagacca
    79201 aaggttagaa aaaacactga aactggacgc aaatatctta tggatatttt gaagaaagac
    79261 aagttaggtg taagaagtat tgacagtatt aagccatcag acgctaaaga atgggctatt
    79321 agaatgagtg aaaatggtta tgcttatcaa accatcaata actacaaacg ttctttaaag
    79381 gcttcattct atattgctat acaagatgat tgtgttcgga agaatccatt tgactttcaa
    79441 ctgaaagcag ttcttgatga tgatactgtc cctaagaccg tactaacaga agaacaggaa
    79501 gaaaaactgt tagcctttgc aaaagctgat aaaacctaca gcaaaaatta tgatgaaatt
    79561 ctgatactct taaaaacagg tcttcgtatt tcagagtttg gtggtttgac acttccagat
    79621 ttagattttg agaatcgtct tgtcaatata gaccatcagc tattgagaga tactgaaatt
    79681 gggtactaca ttgaaacacc aaagaccaaa agtggcgaac gtcaagttcc tatggttgaa
    79741 gaagcctatc aagcatttaa gcgagtgtta gcgaatcgaa agaatgataa gcgtgttgag
    79801 attgatggat atagtgattt cctctttctt aatagaaaga actatccaaa agtggcaagt
    79861 gattacaacg gcatgatgaa aggtcttgtt aagaaataca ataagtataa cgaggataaa
    79921 ttgccacaca tcactccaca tagtttgcga catacattct gtaccaacta tgcaaatgca
    79981 ggaatgaatc caaaggcatt acagtacatt atgggacatg ctaatatagc catgacgctg
    80041 aactattacg cacatgcaac attcgattct gcaatggcag aaatgaaacg cttgaataaa
    80101 gagaagcaac aggagcgtct tgttgcttag tagtacaaat gaatttacta cttatttacc
    80161 acttctgaca gctaagacat gaggaaatat gcaaagaaac gtgaagtatc ttcctacagt
    80221 aaaaatactc gaaagcacat agaataaggc tttacgagca tttaagaaaa tataaaaaga
    80281 taattagaaa tttatacttt gtttatttat aaaaaaacta aatgaattga ttttaaagaa
    80341 ataaaatgct aacatatata gtagatgtta gtattttatt tctaagaaag gagaatgata
    80401 tggttgataa aagagagaaa ctgatgaact ctttcaatca gtatggtttt ttaactttta
    80461 aacaagtaat agatgaaaat ttacactaca aaaccttatt aaaaatggtt gcagaaggaa
    80521 aaatcgatgc tgaagaaaaa gggttatatc gcttacctga tatttattta gatgagtggt
    80581 ttgtccttca gtatcgattt ccaaagggaa tcttttcttt ggagacagca ctttggttac
    80641 atggtttatc tttgactatc ccttttaaca tgacgatgag ttttccttat ggtacgaata
    80701 ccaaaaacat taaggaagca gatatatgtc ctattatctt acgctctcac tatagtgaag
    80761 gaattattga aatagagcgc cttcctggtc aatttattaa agtttatgaa gttgagcgag
    80821 ttttggttga atgtctaaga ccagttcatc aggtggatct tcaaattatt gcaccagcgt
    80881 ttaaaaaata ttttcaacaa aataaaattc atttacacaa attattttat tatgcccagc
    80941 tatttaaagt aactgataag ttacaatctt atacggaggt actatcttaa tgttttcaaa
    81001 tgcgaatagc tttaaagcaa aaatcaaaaa catttcaaaa gataagggaa ttccagctca
    81061 acaagtacaa caacattatt taattgagca agtgttaaag ctgatttcta ctagttctta
    81121 tagagattcc ttcattgtaa aaggagggta tctaataggt caaatgattg gactagataa
    81181 gcgaaccaca atggatttag atgtcactct gaagggaacc gaaatgagca gagaaaattt
    81241 gattcatatc tttgaagaga ttctttgttc taatactgat ggattttcat tttcagtaga
    81301 taagctagaa cctattcgtc aagatgatga atatggagga ttttcattaa aattaaatgc
    81361 aacttttgat acattaaaag aggttgtttt tattgatatt actactggtg ataaaatcac
    81421 accaagagaa attacttatt caatgacttc tatctttact aatgaaagca tcaagatatg
    81481 gacatataat ctagagactg tacttgctga aaagttagaa acaatcatca gtaggggact
    81541 agcttcgacg cgtccacgtg atcgatatga tcttttcacc ttgtataaac ttagaaaaga
    81601 agagattaat cttgaagtat taaaaaatgc acttgagaat acggcagaaa aacgtaaaag
    81661 taaagatact atttataatt gggaagaaca agtgagagga attgaaattt ctgattatca
    81721 gaaagagcta tggattcgtt atcaacgcca atttaagtat gctaaagata tctcatttga
    81781 taactctgtt cagatcatta gggaaattat gcaacaaata ttttagtaca aaagtaactc
    81841 attagtaaag cagtgagttg ctttttttat tccaataact ccaaaaatgt gataaaaatt
    81901 tcaactactc ttatctataa taaagctacc tgttctttga aaattgaatc cactccgtct
    81961 tgattagcgt gcctgtgtaa gtagggactg agagtatttc cctgtgaagg gcaactggca
    82021 caagacgtgt gtgagaattt tctaacagac acggagttta tcgttaccag acttaaacga
    82081 tgcgacaaac tagataaagg agttaatcat gaaggtagta aacttgtatg atttgaaaca
    82141 aatgggaaat aaaggtggtt gtaccatcca attgattcat cactttcctt ttggtatggg
    82201 cttaggacat ctcaaaaaag actacattga atttaaacgt gttggtatcg ttgatgggaa
    82261 ggcagtagaa gtcactcttc gagaacctta ttcgagagat ctactgcagg ttgtcaagtc
    82321 gattaagcaa cgtcagaaat tgatagctta tcgttataaa gaaggaaagc tgctatttgt
    82381 gaagaaggag gcatcagatg tcctctgaac aacaggaacg aatggcagtt caatatgcgg
    82441 agcgtagtct tttatttact gtcaaaagtc tcttaaaaat tctagaatgg tctagacgtc
    82501 aggctttagc acaggattcc gcctataaga taggggtgca gaaattagaa gaattgctac
    82561 aatctcctta ttcgattgat acgattaatc tgaaaaaaga ttttttagac aaaccaattg
    82621 atatagagaa atttaaagct tttttagaaa aagaagagat tcctttagcc atcgcttggc
    82681 aaggggattc tctacatttc tacacgaaag accgttcgat tctggacaat catttagacc
    82741 atctgttaga aaaaatggtt aatgatccgg agaaattagc tgattttacc atggataagt
    82801 cattagacga tgcaattgat gaggcgaaat cccaaattac ctttagacaa gaaggggccg
    82861 tcaaacagaa agagatggtg agatgatgta cagtggaaag aaattcctac tattttcact
    82921 gttaggtatc ttactaggct atctttttca tcgtttgacg cttttgtatg attcctatac
    82981 tggaaataca ttagataaat ggactcatct tctgatggaa ggtcaagatg aagttcttca
    83041 gtcgccatgg aatgtttcct ttactggaaa atccagtgct ttttttctac taggctttgt
    83101 gatgatgttg ctggtttatc tttatttaga gactggcaaa aaacaatacc gagaaggggt
    83161 agaatacggg agcgcccgtt ttggaactct aaaagaaaag aagctctttt acggtaagga
    83221 attttctcat gatacgatct tagctcaaga tgttcgtttg acattattag ataaaaaacc
    83281 accccaatat gatagaaata agaatattgc ggtgatcgga ggttcaggaa gtgggaagac
    83341 atttcgcttt gtgaaaccta atcttattca gatgaatagt tctaatattg tagtggatcc
    83401 taaagatcac ttggccgaaa aaacaggcaa actcttttta gaacatggct atcaagtaaa
    83461 ggtgctagat ttagtcaata tgaagaactc agatggcttc aatccttttc gctatataga
    83521 gacagaaaat gatttgaatc gcatgctgac ggtttatttt aataacacca aaggctctgg
    83581 ctcccgaagt gacccatttt gggatgaagc ttctatgact ttggttcgag ctttagcctc
    83641 ttacttggtc gatttctata atccacccaa aacaagagaa cagctcattg aagagagtcg
    83701 tttgagtcaa aaagaatacc agaacttgtt gaaacgtcaa aaaaaagaag tggaagagcg
    83761 aaaaaaacga ggacgttatc caagttttgc tgaaatctca aaactcatta aacacttatc
    83821 taagggtgaa aaccaagaaa aaagtgtctt agaaattcta tttgaaaatt atgctaaaaa
    83881 gtatggcact gaaaatttta ccatgcgaaa ttgggcagat ttccaaaatt ataaggataa
    83941 gactctggat tctgttatag ctgtaaccac tgctaaattt gccctcttca atattcaaag
    84001 tgtcatggat ttgaccaaaa gagataccct tgatatgaag acatggggcc aggaaaaatc
    84061 aatggtttac ttagttatcc cagataacga tagtaccttt cgctttcttt cagccctctt
    84121 tttttcaacc gtatttcaaa ccctaacaag acaagcagat attgatttta agggtcaatt
    84181 gcctcttcat gtgagagtct acttagatga gttcgcaaat ataggagaaa tcccagattt
    84241 tgctgaacaa acctcaacag tccgttctcg aaatatgagt ctcgttccca ttcttcaaaa
    84301 tattgcccaa cttcaagggc tctataaaga aaaagaagct tggaaaacca ttttggggaa
    84361 ctgtgatagc ttagtctact taggtgggaa tgatgaagat acctttaaat ttatgagtgg
    84421 cttactcggt aaacaaacca ttgatgttcg aaatactagt cgttcctttg gccagacagg
    84481 ttcaggatcc ctttctcatc aaaagattgc tcgtgattta atgacacctg atgaggtcgg
    84541 aaatatgaaa cggcatgaat gcttggttcg aattgccaat atgcctgtct ttaaaagcaa
    84601 aaaatacaat tccactaagc atccaaactg gaaataccta gccaatcaag aaaccgatga
    84661 acggtggtgg aactatcaaa tcaatccttt gaatcaaaga caagaaaatc atcttgaagg
    84721 ccttagaatt cgtgatttaa cttttgaatc tagtttaaaa taaaaataga aaagaggaaa
    84781 tagatgatta cgcattttaa aggttttgtt tatggagtag acgcaagtgc tatgtttgca
    84841 caagctatgt ctttgttaca gaagggtttg attgcggttg gtgcctttct cgttgttgtg
    84901 gggattgtca atcttgcaac caacattaaa gatggtggac caggtgttcg gaatgccatt
    84961 ctggaaattg tcggtggtgt tatggtaggg gctgctggag cctttgtaac tcaaatttca
    85021 atttaggagg ataaacaatg acatgaatct tagtttagtc tcaccctttg tttaccttgc
    85081 atctgaaaaa atatcagctg aaaatttatt tgaagggttt aatgtagatt tacaatctac
    85141 ggtagatctg attaaatccc tatctagcta caatccaaca gtttggactt atatgtctag
    85201 tattactaaa agtgtcatgc agcctcttgg agttgcgatt ttatcagttg ttctcatctt
    85261 agaattttcg aagatggcaa agaaaattgc taactcagga ggagcgatga cctttgaagc
    85321 attagcgccg atgttgatta gttatatcat ggtcgcagtc gtgattacca atactaccgt
    85381 tattgtagaa gccatcatcg ggattgcgag tcacgccatt gaacaagtgg cctcaattgt
    85441 ggctcacggt ggggcaaagt atgataccat ctctggatta aaaggttcag gatttattgg
    85501 ccggatgatt gtgggctttt tcgccctcct catttggcta gttcggatag taagtgcagc
    85561 catggttaac cttttggtat ctattcgatt tattcaactc taccttatga ttccatttgc
    85621 ccctcttacg attccaacat ttttaagtga tgaatggaag tctattggta ttggctattt
    85681 aaaaaatatt atggtttatg cggtacaagg ggttctcatt tttctgattg tttctcttgt
    85741 tcctttattt gaatctgctg ggaaaatagc tgtttcaaat ggtgcaggag tcttgcaatc
    85801 acttgcgatt atgtttggta gtttggtaca agctatctta ctgattattg ccctcgttgg
    85861 ttctcaacgt acggctcgct caatcttagg tatgtaatta gataaaggct aggaagtgat
    85921 tgcttcttag cctttttaga aaggaaagtc atgaatacac gtgtctttaa agacatctca
    85981 aaataccaac acagggcttg gttaggtttc accacaagac aaatcatctt tgttttacca
    86041 gcctttattg tcacaattat tgttttgggc ttgaatctct ttttctggca atttggagat
    86101 tggtttgttt acggttttgt gtttgctttt accatccccc tcatgctttt tggagtctat
    86161 aaacccaatg atttatattt tgaacattat ttgaaatacc gtcttcattt tgaactaacg
    86221 gttcccctac gcacaattac aggaaagaaa ggacctgaac atgaaaagaa aatcaaatac
    86281 attaaagaaa caaaaaactt caatgactaa tcagaaagaa gtagttaaag gaaaaaaaga
    86341 ggaagtgtta ccatcgacgg ctaatactct ttcctatcaa gccctgtatc aaaatggtct
    86401 gatgcaggta aaagaagatt atttctcaca aagctattta cttggtgatg tcaattacca
    86461 gactgttggt ttagaagata agggcgcaat cattgagaag tattctgatt tgattaactc
    86521 cctagacgac caaaccaact tccaattgac tatctttaat aaaagattga atttagaaaa
    86581 gtttagacaa agtgttttgt atgaggaaaa agaagatggg tatgatagct atcgtaaaga
    86641 attgaatcgg atgatgaatc agaatttaga cagtggtgaa aataactttt cagctgtgaa
    86701 actgattagc tttggtagaa aggattctaa tcccaaacaa gcctatcgtt ccttgtctca
    86761 aattggagaa tatttcaaga gtggtttctc agaaattgat gctcgatttg aatctttggc
    86821 tggagaagaa cgggtgaact tgctggcaga tatgcttaga ggagaacacc atcttccttt
    86881 ttcttaccgt gatttaacga gatctggtca gacaactcgt cacttcatag cacctaatct
    86941 cttggatttt aaaaacaaga attacctaca aatcaatgac cgcttattgc agattgtcta
    87001 tgtcagagac tacggtatgg aattaggaga tcagtttatt tgagacctca tgcaaggaga
    87061 tttggaattg attgtgagcc tccatgctca aagttcgacc aaggcggatg ctatgaagaa
    87121 actacgaaca aagaagacct tgatggaatc ccaaaagatt ggggaacaac aaaaacttgc
    87181 tcgtacaggt atctatttgg aaaaagtagg tcatgtatta gaaagcaata tcgatgaagc
    87241 tgaggaactc ttaaaaacca tgaccgagac aggagataaa ctatttcaaa cagtattctt
    87301 gattggtgtt tttggtcagg atgaagaaga acttaaacaa gctctagata cgattcaaca
    87361 agtggccggc tcaaatgacc taatgattga taaactacca tatatgcaag aagcagcctt
    87421 taatagtttg ctgccatttg gttgtgattt tttagaggga gtatcacgga gtttattaac
    87481 atccaatata gcagtgaact ctccatggac ttcagtagac ttacaagacc gtagtggaaa
    87541 atattacggt atcaatcaaa tctcaagcaa tattattacc attgatcgca gcctattaaa
    87601 tacaccgtct ggtctgattt tagggacatc tggagctggg aaagggatgg caaccaagca
    87661 tgaaattatc acgacccaaa tcaaggaatc tggtgaaaat actgaaatta tcatcgtgga
    87721 tccagaagca gaatacagtg tcattggacg agcttttggt ggagaaatga ttgatattgc
    87781 gcccgattcc caaacttatc tcaatgtcct tgatttgtct gaggaaaata tggatgaaga
    87841 tcctgtaaag gtaaaatcag aatttctttt atcctttatc ggcaagttat tggatagaaa
    87901 aatggatgga agagaaaaat cgattatcga ccgagtcaca agactcacct atcagtcatt
    87961 taaagagcct tctttggaag aatgggtctt tgtcttgagc caacaaccag aagaagaagc
    88021 gcagaatttg gcacttgata tggaactgta tgtcgaaggt tctcttgata ttttttctca
    88081 taagaccaat attcagacag gatctaattt cttgatttat aacgttaaga agttaggaga
    88141 tgagctgaaa caaatcgccc ttatggttgt ttttgatcag atatggaatc gtgtcgttcg
    88201 gaatcaaaaa ttagggaaga agacctggat ttattttgat gaaatgcagc ttctcttatt
    88261 agataaatat gccagtgatt tcttctttaa attgtggagt cgtgtcagaa aatatggagc
    88321 cagtctgact ggaataactc aaaacgtcga aaccttattg ttagatccaa atggtagacg
    88381 gattattgca aatagtgaat ttatgattct tctcaagcaa gcaaaaaatg accgagaaga
    88441 actggttcaa ctcttaggct tgtcaaaaga actcgaaaaa tacctagtca atccagaaaa
    88501 aggagcagga ctgataaaag ctggttcagt tgtcgtacca tttaaaaata agattcctca
    88561 aggtactcaa ttgtttgata ttatgagtac ggatcctgat aaaatggctt ctaattaagg
    88621 ggaaggtaaa tgaaggataa aagagaaatc atacgtgccc gaaaagcatt tagaagaagt
    88681 ctaaaagatg agaagaaatt cttgaaacaa ggaaagaagg aggtgaggaa acagaaaaaa
    88741 gattccgctg tactggatga aaaagcatgg aaaaaagaga taaaagaaaa gctagaggag
    88801 atgagagaag cttcaaagga gagagtaaaa caagcaaatg aagactacaa tcatattctt
    88861 caaaatagtc ctccatcttt tttgaatcgt aaagaattaa gagacagacg attacctcat
    88921 gctaggaaac gattgaaaat agccaagaag caatttagag aagccaaggt agaagcaaaa
    88981 gaagaaagaa aagagagtcg taaagaaaga aaaaccaatc aaaaatttct ctacggtcag
    89041 gaatcgaaac aaaaatctaa ttttttcttt caagggaaga gtttagaaga attaaaagct
    89101 aagaaagaag tcaaggctgc taaagaaaat ttaaaatcta ctaaacaagc ctataagtac
    89161 aaaaaagtca gtaggaaagc caaaactttt ctttatgtcc ttggacgtga aggtggagag
    89221 ttagcttcag aaaatgaaga tttagaaggc tatcgcacac ttcaagagac cattagaaaa
    89281 gggaaacgct acagtcggct ttcttataat cttggaaaag ctagtgtcaa aacaggacaa
    89341 gcaacaggtc gttttaccaa gaaaagactg accaacacaa aagagcgata ccatcatttt
    89401 aaggatggaa aaggatggaa actagcaaaa gataacccaa gttcctttaa gaatcggttt
    89461 cgaaaattaa agaaacaagg tctttcaagt gtccaaaata tctatcaaaa actaaaagca
    89521 gccttttcct tctttacatt tgcggctgga aatcctgcaa catggatagt tggaggaata
    89581 gtctttcttc ttttacttat gatgagcttc ttcttaggat tttcatctgc tagtttgatt
    89641 caacaagatg aatttgaatt aacaaaagct tatacccacc taacttggga agatgcagaa
    89701 catactcgca caaatgacaa aggaattacc tattacacaa aagttgatga tgtgatgggg
    89761 tatatgaact ttaaattcca tgactatgag ttacagaaac cagttcactt atttagttca
    89821 gaaacttaca aggattatct gtctactttg tggcatgatt taaacgatgg tgatgatttg
    89881 aaatccatgc aagacctcta tgaaactcct aagtataaac tatcgaaaga cgatcaagag
    89941 gaaataaagg aactaaaaga agaaggtgtg tatgcttcca tgcaggaatt agacaatcca
    90001 tttgagggac aaagcaacga agatagtcta accatgactt atcgttatgg atactatgat
    90061 ttagatggga aacctactct tcaggagtac atcctactag aagcaaaggc tcaccaaacg
    90121 attgtcgcac caatggatgc agttgtatct ctagatggtg acaatattat tctcactaac
    90181 ggaaaaggag agaatgagag tcgattaacc ttgtattcta ttcataatgg ccgtgcgatt
    90241 gaggggacaa gagtcctaac gggtgatatt attggtgaaa caccagacga tacaggtttg
    90301 aaagtttcct atcaaaagta taagaacaag aaagaaaaat tggtgtatgt caatccgcaa
    90361 ttttattttc caaaagtcat tcaacttcag accactatct tacctgccat tggtcagttt
    90421 ggtggggatg agtttgaacg agcaaaacat atttatgatt ttttgaaatc tcaaggcgta
    90481 agtccccaag ccattgcggc tattttagga aattggtctg tagagtcttc tattaatcca
    90541 aaacgagctg aaggagatta tttatctcct ccagttggcg ctaccgattc ctcatgggat
    90601 gatgaaagct ggttagcgat tggaggtcca gccatttata gtggtgctta tcctaatatt
    90661 cttcatagag gtttggggtt agggcaatgg acggatactt cagatggttc aacacgttat
    90721 acagctttat tgaattatgc acatagcaaa aataagaagt ggtatgattt agacctccaa
    90781 cttgatttta tgcttcatgg ggatagtcct tactaccaaa gttggttaaa agatttcttt
    90841 aaaaatacgg gcagtgcagc caatctcgcc caactcttcc tcacctattg ggagggaaat
    90901 tctggtgaca aattactgga aagacaaacc agagcaacgg aatggtatta ccaaattgaa
    90961 aaaggcttca gccaaacaaa tggaggacag gcaaaaagtg acccacaatc ccttgaaggg
    91021 gttcgtgggg acttgtatga tcattctgtt cctggtggtg gagatggtat ggcctatgcc
    91081 tatggacaat gtacatgggg tgttgcggct cgtatgaatc aattaggctt aaaattaaaa
    91141 ggaagtaatg gagagaagat ttcaatcatt aataccatgg gaaatggtca ggactgggtt
    91201 gcgacagctt caagtcttgg tggggaaact ggctctacac caagagcagg tgctattgtt
    91261 tcttttgtgg gaggtacaca tggcacacca gcagactatg gtcatgtagc ttttgt
//
LOCUS       DAVDHZ010000004        85084 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000004 DAVDHZ010000000
VERSION     DAVDHZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 85084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.004"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            187..444
                     /locus_tag="VUR46_000325"
     CDS             187..444
                     /locus_tag="VUR46_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET5455823.1"
                     /translation="MQINLENLVSITEANQNFSKVARMVDSKGTAVILKNNKPKYILV
                     DYNTLIQEEQTEAIIADQTGVDEVANSILSRHLEAFKELAK"
     gene            441..812
                     /locus_tag="VUR46_000326"
     CDS             441..812
                     /locus_tag="VUR46_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001221831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET5455824.1"
                     /translation="MKRLTTEQVLALHRQLIVASGGMDGIRDKGLVESSLSNVFDTYF
                     EVEQYLTIEEKAARLCYSLIKNHAFLDGNKRIGIFVMLVLLEINDIVLDCTDEELVHL
                     GLGVATSKLTYEDILDFVKNH"
     gene            complement(1011..1841)
                     /gene="glf"
                     /locus_tag="VUR46_000327"
                     /pseudo
     CDS             complement(1011..1841)
                     /gene="glf"
                     /locus_tag="VUR46_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002890901.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(2164..4122)
                     /locus_tag="VUR46_000328"
     CDS             complement(2164..4122)
                     /locus_tag="VUR46_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5455825.1"
                     /translation="MNTKKRVLSTGLTFVAALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNTSIITNLVDGLLENDNYGNLVPSLAEDWSVSSDGLTYTYKLRKDAKWF
                     TADGEEYAPVKAQDFVTGIKYAVDNKSQAIDLIQNSIKGLNDYIIGADSDFSKVGVKA
                     IDDQTVEYTLTRPEPYWNSKTTNSILFPVNEEFLNSKGKDFGTLSPDSILYSGPYLLK
                     DFTSKSSIEYVKNPHYYDHDKVSIEHVKLAYFDGSDQELTIRNFESGAYSIAGVYPNS
                     SNFAKTKEKYKDNIVYSLQDKTSWYFNFNVNRKAYNHTAKMTDEQKKSTETAVLNKNF
                     RQAVNFALDRTAYSAQSNGEEAASKTLRNTLVPPTFVQVGDKTFGEVVASKLVNYGTE
                     WSGINLEDAQDAYFNKEKAQAKFAEAKKELTSQGVTFPIHLDVAVDQTSKNAVTGMNS
                     VKQTLESVLGADNIVIDVQQLSTDDFNNVAFLAPTPADRDYDLNFDGWVGDYQDPSTY
                     LNPFNAEDGFYLKIFGLDAKEDKEKITSLGLDAYTKMLKDADSENKDVAKRYEKYAEA
                     QAWMIDNSLVMSAMSSGGTASVTKVTPFTRGYSLVGIKGDGDNYKYMKLQKDTVTTKQ
                     FEEAKTKWEQESKKAIEKAQKEAEKHVK"
     gene            complement(4326..6293)
                     /locus_tag="VUR46_000329"
     CDS             complement(4326..6293)
                     /locus_tag="VUR46_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5455826.1"
                     /translation="MQSKKWLLGAGVTLTTALLLTACGKSEKNADAPKTFSYVYAVDP
                     SSLDYSVTSKNSTSDVIGNVVDGLLENDKYGDLIPSLAEDWSVSKDGLTYTYKLRKGV
                     KWYTSEGEEYAKVKAQDFVTGLKHAADGKSDGLSLVEKSIKGLEAYVSGETNDFSTVG
                     VKALDDYTVEYTLNQPESFWNSKVTTATMLPVNEEFLNATGKDYGAPTPSSILYNGPY
                     FLKSLISKSVIEYEKNPNYWDKENVKIDNVKLTFYDGSDQESLIRSFTQGAYTTARLF
                     PASSNFESTKKEYGDKIVYSPQEATSYYLTVNVNRQSYNKTAKTDESQKTSTKEALLN
                     KNFRQALNFAFNRHAYTAQLNGEEGADKIIRNSLVPDNYVQVAGKTFGQLAQDELLKY
                     GEQWKDVTLTDGKDTIYNPTKAKSAFEKAKSELQAKGVSFPIHLDVPVEQTDVVAVQQ
                     TNSLKQSIEETLGTENVIIDVLQMTDNEKESITSQAKVPTQKDYDLNGTGWGPDYQDP
                     ATYLNILDAKKGSALKHLGITKGKDPEVVAKVGLDEYKNLLDDAASETSNLDKRYGKY
                     AKAQAWVTDSSLLIPVASSGGSPMVSRTVPFTKAYSQVGIKGDPFIFKGMELQNDIVT
                     TKEYEAAFKKWQKEKLESNAQYQKDLEKHVK"
     gene            complement(6569..8179)
                     /locus_tag="VUR46_000330"
     CDS             complement(6569..8179)
                     /locus_tag="VUR46_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET5455827.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIEEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMDFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKNLLTVGETWGATPEIAKLYSDPKGQELSMVFHFEHIGLQYQEGQPKW
                     HYQKELNIPKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFGTLNQVEDIESLNYAREALEKGVPMEEIMDS
                     IRVIGRDNARTPMQWDKSKNAGFSTGQPWLAVNPNHQEINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRSDFELLETADKVFAYIRKDGDRRFLVVANLSNEEQDLIVEGNVKSV
                     LIENTAAQEVFEKQILAPWDAFCVELTD"
     gene            8331..9815
                     /locus_tag="VUR46_000331"
     CDS             8331..9815
                     /locus_tag="VUR46_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET5455828.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVAASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            9910..10392
                     /locus_tag="VUR46_000332"
     CDS             9910..10392
                     /locus_tag="VUR46_000332"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET5455829.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAEIAAV
                     IKDSLKEIAETTTWEEVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(10454..12559)
                     /locus_tag="VUR46_000333"
     CDS             complement(10454..12559)
                     /locus_tag="VUR46_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5455830.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAEADGQMPQHTSGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     EVEKDKQEKAVESEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGPTGVGKTELAKQLALDMFGTKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLD
                     AKHLEADMEDGVLVIREKS"
     gene            complement(12898..13878)
                     /locus_tag="VUR46_000334"
     CDS             complement(12898..13878)
                     /locus_tag="VUR46_000334"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET5455831.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIAAVVVSFLVALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYILFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKMTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(13880..16132)
                     /locus_tag="VUR46_000335"
     CDS             complement(13880..16132)
                     /locus_tag="VUR46_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HET5455832.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNRILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQ
                     MDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEGITEDFVWRDILYQSNYE
                     PGSAMKVMTLASSIDNNTFPSGEYFNSSEFKIADATTRDWDVNEGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAA
                     STTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST
                     NYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPA
                     KNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAP
                     NQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGSVVQKQDVRTNTAIKN
                     IKKIKLTLGD"
     gene            complement(16136..16453)
                     /gene="ftsL"
                     /locus_tag="VUR46_000336"
     CDS             complement(16136..16453)
                     /gene="ftsL"
                     /locus_tag="VUR46_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET5455833.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(16465..17415)
                     /gene="rsmH"
                     /locus_tag="VUR46_000337"
     CDS             complement(16465..17415)
                     /gene="rsmH"
                     /locus_tag="VUR46_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET5455834.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQERLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPVETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            17582..17776
                     /locus_tag="VUR46_000338"
     CDS             17582..17776
                     /locus_tag="VUR46_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5455835.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            17792..18334
                     /locus_tag="VUR46_000339"
     CDS             17792..18334
                     /locus_tag="VUR46_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET5455836.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITAIDPDLLSEKE
                     SKQLYYPGLKAGLFFGLWMFFITPLLSILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKAKKDQDED"
     gene            18344..18586
                     /locus_tag="VUR46_000340"
     CDS             18344..18586
                     /locus_tag="VUR46_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455837.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENSNFISSL
                     LNTKHIFKTILGAFFFGVMMHIVDSLRIARAKKDQD"
     gene            18597..18923
                     /locus_tag="VUR46_000341"
     CDS             18597..18923
                     /locus_tag="VUR46_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455838.1"
                     /translation="MKSLVTLLTYHLLFSSLLIFIIVSGNLPIYDIVLLPVFVPALNK
                     GLTYLKIDSPKTRILNLALCFMILSLPQLMLISSDWKYYLLLTIASLSSITYLYYLYQ
                     FVKENQ"
     gene            18950..19528
                     /locus_tag="VUR46_000342"
     CDS             18950..19528
                     /locus_tag="VUR46_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET5455839.1"
                     /translation="MKKEDLTTRLLRNLFHIQGPFDECRQEIIYKACARFMVQIVYSS
                     FFLFLFYLLFGRFIEVVRYAMPYVCFGLIFFITLKTQRAVKELHLEKDDKSEIILKTY
                     SKAQIKFRSWIVFIGLQIGLFTLLIFHKVFVQQMSFSDFVKLLMQFDKSVPFLMYGLI
                     IGSIFGTLTYGFLSLQEEKTPKNTKQKEKSNQ"
     gene            complement(19799..20800)
                     /locus_tag="VUR46_000343"
     CDS             complement(19799..20800)
                     /locus_tag="VUR46_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5455840.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIKKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSTQIVKGIEDIASQSGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSRLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHARLT
                     IEDKHTNLEQIKEFLQKEINPDEKTLVFVPNCWALPPVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPAFEEGQQATKILIDQIEGLNQEERQQVLDCSVSWKESTF"
     gene            complement(20860..22761)
                     /locus_tag="VUR46_000344"
     CDS             complement(20860..22761)
                     /locus_tag="VUR46_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET5455841.1"
                     /translation="MKEERRQFFERIDGDQYRDYILSRCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWNQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFRPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEEELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPILATYHFFSDKMDLEEAYHFASKELKQQ
                     IETQILEDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSFQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAMVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFRSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREVDERYLLKSAWSHSTCIVDGKAPERIVGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYLSAEPDLPYLHRRKILMLAEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLKLWSEVDFDLEDTIISPKYNELEKSSKLIKHQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDGHQVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(22783..23076)
                     /gene="yajC"
                     /locus_tag="VUR46_000345"
     CDS             complement(22783..23076)
                     /gene="yajC"
                     /locus_tag="VUR46_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET5455842.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRKEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(23076..23894)
                     /locus_tag="VUR46_000346"
     CDS             complement(23076..23894)
                     /locus_tag="VUR46_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5455843.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKILA"
     gene            complement(23881..24660)
                     /locus_tag="VUR46_000347"
     CDS             complement(23881..24660)
                     /locus_tag="VUR46_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5455844.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            complement(24675..25166)
                     /locus_tag="VUR46_000348"
     CDS             complement(24675..25166)
                     /locus_tag="VUR46_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET5455845.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIEE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELNQTYQVTFNTKTTPTGNDGAVEVNIM
                     DYI"
     gene            complement(25177..26367)
                     /locus_tag="VUR46_000349"
     CDS             complement(25177..26367)
                     /locus_tag="VUR46_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET5455846.1"
                     /translation="MIKKVTIEKIKSPECFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFNLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(26379..26813)
                     /locus_tag="VUR46_000350"
     CDS             complement(26379..26813)
                     /locus_tag="VUR46_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5455847.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            27085..27900
                     /locus_tag="VUR46_000351"
     CDS             27085..27900
                     /locus_tag="VUR46_000351"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET5455848.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASDFVNGHILYVDGGILAYIGKQPE"
     gene            27919..28560
                     /locus_tag="VUR46_000352"
     CDS             27919..28560
                     /locus_tag="VUR46_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET5455849.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATNKKGYQLFNYGMRGEEGE
                     NPLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITYNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            28591..29592
                     /locus_tag="VUR46_000353"
     CDS             28591..29592
                     /locus_tag="VUR46_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET5455850.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYFLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGIGHFHFSGITVAIGQEVRTLLLLLLEEAKRRGI
                     IVSMDLNLRTKMISVLEAKYEFSKFARFADYCFGIDPLMIDDQNLEMFPRDRASLKEV
                     ENRMRQLKEAYGFKAIFHTLRSSDEQDKNVYQAYALGERFEESVQLKTAVYQRVGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSETSIEKLLANAQDIIR"
     gene            29602..30231
                     /locus_tag="VUR46_000354"
     CDS             29602..30231
                     /locus_tag="VUR46_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET5455851.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVIDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGDFDRISEIAQQYVTLR"
     gene            complement(30325..33529)
                     /locus_tag="VUR46_000355"
                     /pseudo
     CDS             complement(30325..33529)
                     /locus_tag="VUR46_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            33752..34228
                     /locus_tag="VUR46_000356"
     CDS             33752..34228
                     /locus_tag="VUR46_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET5455852.1"
                     /translation="MTSLYDFSVLDQNNQSTPLETYRGKVLLVVNTATGCGLTPQYQG
                     LQELYDRYQEQGFEILDFPCNQFMGQAPGSAEEINTFCSLHYQTSFPRFAKIKVNGKE
                     ADPLYVWLKEQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(34450..36663)
                     /locus_tag="VUR46_000357"
     CDS             complement(34450..36663)
                     /locus_tag="VUR46_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET5455853.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHCYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMIEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTANFEWKDNKTPSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTNEN"
     gene            complement(37065..37241)
                     /locus_tag="VUR46_000358"
     CDS             complement(37065..37241)
                     /locus_tag="VUR46_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455854.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            37388..37810
                     /locus_tag="VUR46_000359"
     CDS             37388..37810
                     /locus_tag="VUR46_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5455855.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            complement(38072..38464)
                     /gene="rpsI"
                     /locus_tag="VUR46_000360"
     CDS             complement(38072..38464)
                     /gene="rpsI"
                     /locus_tag="VUR46_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET5455856.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(38484..38930)
                     /gene="rplM"
                     /locus_tag="VUR46_000361"
     CDS             complement(38484..38930)
                     /gene="rplM"
                     /locus_tag="VUR46_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET5455857.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            39287..39604
                     /locus_tag="VUR46_000362"
     CDS             39287..39604
                     /locus_tag="VUR46_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET5455858.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPLYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(39649..40461)
                     /gene="folB"
                     /locus_tag="VUR46_000363"
     CDS             complement(39649..40461)
                     /gene="folB"
                     /locus_tag="VUR46_000363"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HET5455859.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFETYPLVQEIKLELKKPWA
                     PVHLPLDTCSVTIHRRKQRAFIALGSNMGDKQANLEQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVIEVETWLPAPVLLETLLAIESEMGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIASHFIHPTLKQPIRNLYNALKK"
     gene            complement(40504..41058)
                     /gene="folE"
                     /locus_tag="VUR46_000364"
     CDS             complement(40504..41058)
                     /gene="folE"
                     /locus_tag="VUR46_000364"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET5455860.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(41039..42361)
                     /locus_tag="VUR46_000365"
     CDS             complement(41039..42361)
                     /locus_tag="VUR46_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET5455861.1"
                     /translation="MKEFENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     RSLLEGESATNLQGTTEFEIITAIAYDYFALEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGTPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(42363..43340)
                     /gene="folP"
                     /locus_tag="VUR46_000366"
     CDS             complement(42363..43340)
                     /gene="folP"
                     /locus_tag="VUR46_000366"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET5455862.1"
                     /translation="MVKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGRSSYVEIEEEIQRVVPVIKAIRKESNVLISID
                     TWKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVIARPQHPSSL
                     IFPHFGFGQAFTEKELADFETLPIEDLMETFFDRALARAEEAGIAQENILLDPGIGFG
                     LTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTA
                     SAHVTSIAVRQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(43434..44141)
                     /locus_tag="VUR46_000367"
     CDS             complement(43434..44141)
                     /locus_tag="VUR46_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5455863.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTVVFALLHQPSNLPSLLIYGGMSIVLSWTAYKTQRLEMSILLHMIVNGVAF
                     CLLALVVILSRTLGISV"
     gene            complement(44194..45612)
                     /locus_tag="VUR46_000368"
     CDS             complement(44194..45612)
                     /locus_tag="VUR46_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET5455864.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            45802..46614
                     /locus_tag="VUR46_000369"
     CDS             45802..46614
                     /locus_tag="VUR46_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5455865.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            46953..47972
                     /gene="adhP"
                     /locus_tag="VUR46_000370"
     CDS             46953..47972
                     /gene="adhP"
                     /locus_tag="VUR46_000370"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET5455866.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIATADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            48205..49194
                     /gene="manX"
                     /locus_tag="VUR46_000371"
     CDS             48205..49194
                     /gene="manX"
                     /locus_tag="VUR46_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET5455867.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            49222..50025
                     /locus_tag="VUR46_000372"
     CDS             49222..50025
                     /locus_tag="VUR46_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET5455868.1"
                     /translation="MSIISMVLVIVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            50049..50960
                     /locus_tag="VUR46_000373"
     CDS             50049..50960
                     /locus_tag="VUR46_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5455869.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(51016..52350)
                     /gene="pepC"
                     /locus_tag="VUR46_000374"
     CDS             complement(51016..52350)
                     /gene="pepC"
                     /locus_tag="VUR46_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET5455870.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(52567..53289)
                     /locus_tag="VUR46_000375"
     CDS             complement(52567..53289)
                     /locus_tag="VUR46_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET5455871.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(53557..53787)
                     /locus_tag="VUR46_000376"
     CDS             complement(53557..53787)
                     /locus_tag="VUR46_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET5455872.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(53797..55038)
                     /locus_tag="VUR46_000377"
     CDS             complement(53797..55038)
                     /locus_tag="VUR46_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET5455873.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(55060..55212)
                     /locus_tag="VUR46_000378"
     CDS             complement(55060..55212)
                     /locus_tag="VUR46_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455874.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(55233..55511)
                     /locus_tag="VUR46_000379"
     CDS             complement(55233..55511)
                     /locus_tag="VUR46_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET5455875.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(55504..55767)
                     /locus_tag="VUR46_000380"
     CDS             complement(55504..55767)
                     /locus_tag="VUR46_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET5455876.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(55869..60260)
                     /locus_tag="VUR46_000381"
     CDS             complement(55869..60260)
                     /locus_tag="VUR46_000381"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET5455877.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(60364..62445)
                     /gene="fusA"
                     /locus_tag="VUR46_000382"
     CDS             complement(60364..62445)
                     /gene="fusA"
                     /locus_tag="VUR46_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET5455878.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(62870..63340)
                     /gene="rpsG"
                     /locus_tag="VUR46_000383"
     CDS             complement(62870..63340)
                     /gene="rpsG"
                     /locus_tag="VUR46_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET5455879.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(63360..63773)
                     /gene="rpsL"
                     /locus_tag="VUR46_000384"
     CDS             complement(63360..63773)
                     /gene="rpsL"
                     /locus_tag="VUR46_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET5455880.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            complement(64265..65611)
                     /locus_tag="VUR46_000385"
     CDS             complement(64265..65611)
                     /locus_tag="VUR46_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET5455881.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVANMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            65898..69668
                     /gene="spuA"
                     /locus_tag="VUR46_000386"
     CDS             65898..69668
                     /gene="spuA"
                     /locus_tag="VUR46_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET5455882.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDATSIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEVHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVRNESV
                     ENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            complement(69768..70817)
                     /locus_tag="VUR46_000387"
                     /pseudo
     CDS             complement(69768..70817)
                     /locus_tag="VUR46_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
     gene            complement(71069..72205)
                     /locus_tag="VUR46_000388"
     CDS             complement(71069..72205)
                     /locus_tag="VUR46_000388"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HET5455883.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKSGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLITKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDPELIEQIVEYI"
     gene            complement(72267..72704)
                     /locus_tag="VUR46_000389"
     CDS             complement(72267..72704)
                     /locus_tag="VUR46_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5455884.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(72706..74661)
                     /locus_tag="VUR46_000390"
     CDS             complement(72706..74661)
                     /locus_tag="VUR46_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5455885.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECMKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(74685..76454)
                     /locus_tag="VUR46_000391"
     CDS             complement(74685..76454)
                     /locus_tag="VUR46_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HET5455886.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGSLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMLIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDISTSASVDSQEIDFNHIDAVVVAYGKAQ
                     GSATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQTAPNS
                     QFLIVDSLVTTPEYDKMAVRMYK"
     gene            complement(76899..78707)
                     /gene="glmS"
                     /locus_tag="VUR46_000392"
     CDS             complement(76899..78707)
                     /gene="glmS"
                     /locus_tag="VUR46_000392"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET5455887.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDSNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEVGQ
                     VVVDQAIIQAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANHTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLTLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKETDAIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(78900..80279)
                     /gene="bglA"
                     /locus_tag="VUR46_000393"
     CDS             complement(78900..80279)
                     /gene="bglA"
                     /locus_tag="VUR46_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET5455888.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVLAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(80378..82231)
                     /locus_tag="VUR46_000394"
     CDS             complement(80378..82231)
                     /locus_tag="VUR46_000394"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET5455889.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(82244..83503)
                     /gene="rseP"
                     /locus_tag="VUR46_000395"
     CDS             complement(82244..83503)
                     /gene="rseP"
                     /locus_tag="VUR46_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET5455890.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(83525..84328)
                     /locus_tag="VUR46_000396"
     CDS             complement(83525..84328)
                     /locus_tag="VUR46_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET5455891.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(84337..85065)
                     /locus_tag="VUR46_000397"
     CDS             complement(84337..85065)
                     /locus_tag="VUR46_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET5455892.1"
                     /translation="MEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFGHKAGMEALQT
                     VTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPELHANNVKIQMI
                     GETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLISQDVLDAKIN
                     PGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYSELYFTDTLWP
                     DFDEVALQEAILAYNRRHRRFGGV"
BASE COUNT        24955 a        18962 c        15789 g        25378 t
ORIGIN      
        1 ccctttttca agttctgtca atagaatttt ctgaatttta agagttattt gttatatttg
       61 atctattctg aaaagcatat ttacagttga ttgaaactag actagtacac aataggacaa
      121 atatagccta tattcttgtt tttgttgctc aaaaatggta tgataaaata aaaggagaag
      181 atgataatgc aaattaatct tgagaattta gtttcaatca ccgaagcaaa tcaaaatttt
      241 tctaaagttg ctcgtatggt tgatagcaaa ggcacagctg ttattttgaa aaataataaa
      301 cccaaatata ttttagtcga ctataatacc ctgattcaag aagaacaaac agaagccatt
      361 attgctgatc aaactggtgt tgacgaggtg gcaaattcta ttttatcacg ccatttagag
      421 gcctttaagg aattagccaa atgaagcgat taaccactga acaggttctt gccttacatc
      481 gccaattgat tgtagcttcg ggaggaatgg atggtatacg agataaaggg ttagttgagt
      541 catcactttc taatgttttt gatacctatt ttgaagttga gcaatatttg actatcgaag
      601 agaaggcagc tagactttgt tattctttga ttaagaacca tgctttttta gatggaaaca
      661 aacgcattgg tatttttgtg atgcttgtac tattagaaat taacgatatt gtacttgatt
      721 gtactgatga agaattagtt catcttggat taggtgtagc aacatcaaaa ttaacttatg
      781 aagatatttt agattttgtg aaaaaccatt gatacaaaaa gcaggtgatt ttctatcaat
      841 cacttgcttt gcttttaatt tattcgaaaa tagtaacggt gtgacttttt ggtaatcata
      901 ctcaatgaaa atcaaagagc aaactaggaa gctagctgca ggttgctcaa agcactgctt
      961 tgaggttgta gataaggcaa cgttgacgca gtttgcagag attttcgaag agtataagga
     1021 atttctcgtt ctgtatagtt gacaacagca tttccttgat agttttcttc atggagaact
     1081 ttatgctcaa aacgaagact acggtattct aactcaccat gtttataatc gaagtattgg
     1141 tcgatcatcc ctgtaaagac aactttttca gcagaagctt ctaattcttg acgattagca
     1201 aaaaagtcaa ggccaagttc tacttctaca tccttcatca tgttttcgat gatgacatta
     1261 tagccaccga ttggaatccc ttgataacgg tcgttaaaat aattattatc aaaggttaaa
     1321 cgaactggta gacgtttgat gataaagggt ggaaggtcag tcgcagaacg tccccattgc
     1381 ttttcagtat accctttaat caacttttca taaatatctg agccgatcaa cttgatagcc
     1441 tattcttcta agtttttcgg ttcaacatcc ttcatatgag ccgtttgctc agcaatctta
     1501 tctttgactt cttgaggagt ttttgtaccc cacatagcat agaaagtatt catattgaaa
     1561 ggtagattat aaaggctacc cttgtaatta gctagaggcg aattgatata gttgttaaat
     1621 tcagcaaatt gattaacata attccagact ttcttattgg aagtatggaa gatatgggca
     1681 ccatatttat gaacattgat tccttctaca ttctcacagt agatattccc accaatgtgg
     1741 tcacgtttat caataacttt tacttttttt ccccgcttgg ttgcttcata agcaaaaatt
     1801 gctcctgaca aaccagcacc aacgattaga tagtcgtaca tagtctcttt tatctctcat
     1861 ctccttaact atagcaaaag agaggatatt atactcttcg aaaatctctt caaagtacgt
     1921 cagcgtccat ctgcaacctc agaacagtat tttgagctga cttcgtcagt tctatctacc
     1981 acctcaaagc tgtactttga gctagcttcc cagttgctct ttgattttca ttgagtattc
     2041 gtttcaatct attttagcac aaaacaaatc atttctcagt tttcaatagc cgagtaattt
     2101 aaaaagacaa gcaccaaaac taatgtttgt ctttatgatt ttgcttgaaa aggctatttc
     2161 taactattta acatgttttt ctgcttcttt ttgggctttt tcgattgctt ttttgctttc
     2221 ttgctcccat ttggtcttag cttcttcaaa ctgtttggtt gtcaccgtat ctttttgcaa
     2281 tttcatgtac ttgtagttat cgccatcacc cttgatgcca accagtgagt agcctcttgt
     2341 aaatggcgtt actttggtta cagatgctgt gccaccactt gacatagctg acatgactag
     2401 agaattgtca atcatccaag cctgtgcttc agcatatttt tcatagcgtt tggctacatc
     2461 tttattttca ctatctgcat ctttgagcat cttagtgtag gcatccagac ctaggctagt
     2521 gattttttcc ttgtcttcct tggcatctag tccaaaaatc ttgagataga agccatcctc
     2581 tgcattgaaa ggattgagat aagttgatgg atcttggtag tcacctaccc aaccatcaaa
     2641 gttcaaatca tagtcacgat cagctggtgt cggtgctaag aaagctacgt tattaaaatc
     2701 atctgttgaa agttgctgaa cgtcaatgac aatgttatca gcacccaaaa ctgactcaag
     2761 ggtctgctta actgagttca taccagtcac agcattttta cttgtctgat caactgccac
     2821 atccaagtga attgggaagg tcacaccttg acttgtcaat tcttttttag cttccgcaaa
     2881 ttttgcttgg gctttttctt tgttgaaata ggcatcctga gcatcttcca agttaatacc
     2941 tgaccattct gttccgtaat tgaccaattt agaagcgact acttctccaa aggtcttgtc
     3001 tccaacttgg acaaatgtag gaggcactag ggtgttacga agggtcttgc tagctgcttc
     3061 ttccccattt gattgggcag aataggctgt gcgatccagg gcaaagttca ccgcttgacg
     3121 gaagtttttg ttcaagacag ctgtctcagt tgacttcttc tgctcatctg tcattttagc
     3181 agtgtgattg taagccttac gattgacatt gaaattgaaa taccaagaag tcttgtcctg
     3241 caagctatag acgatattat ccttatattt ctccttggtc ttggcaaagt tagaactatt
     3301 tggataaaca ccagcgattg agtaagctcc actttcaaag ttacggatgg tcaattcttg
     3361 gtctgaacca tcaaaataag ccaatttcac gtgttcaatc gatactttgt catgatcata
     3421 gtaatgcgga tttttcacat actcgatcga tgatttcgat gtgaagtctt ttaacaaata
     3481 aggtccgctg tagagaatgc tatctggaga tagagttcca aaatctttcc cttttgaatt
     3541 tagaaactct tcgtttactg ggaaaagaat actgttcgtt gtttttgaat tccagtaagg
     3601 ttctgggcgt gtcaaagtat actcaacagt ctggtcgtcg attgctttca caccaacctt
     3661 agaaaagtca gaatccgctc ctataatata atcattcaag cctttaatcg agttttgaat
     3721 caagtcaatg gcctgtgatt tattatccac tgcgtacttg atacctgtca caaaatcctg
     3781 ggccttgact ggcgcgtact cttcaccgtc agccgtgaac catttggcat cttttcttaa
     3841 tttataggta taagtcagac catcgcttga aacagaccag tcttctgcca aagatggaac
     3901 tagattccca taattgtcat tttcaagcaa accatcaact agattggtga taatcgatgt
     3961 attatctgcg tagtagtcta ataaatagtt aaatgtagtt ggatttccac taaaggtcga
     4021 tgagtaagtt tttgtatctg aacctgattg tccgcaagca gctaaaagca aagcagccac
     4081 aaaagtcagg cctgtactaa ggacacgctt ttttgtattc atcttctttc tcctttatgt
     4141 tagtttttat aacataagtt tattttacca aaatcatggg aatttgtaaa gttaattgaa
     4201 ttttgagaat gaaagtttat aaatttcggg tatataaaaa caaaggattt ctgcctttca
     4261 tacaatcctc ctttgttttt atacgattta ttaattaaaa attatttgtg aaaacaagcc
     4321 tagactcatt ttacgtgttt ttctaaatcc ttttgatact gagcattcga ttccagtttt
     4381 tccttttgcc actttttgaa ggccgcttca tactctttag ttgtcacgat atcattttga
     4441 agttccatac ctttaaaaat aaatggatcc cccttaatac cgacctgtga ataagctttg
     4501 gtaaatggaa cagtacgact aaccatagga gagccccctg aagaagcaac tggaataaga
     4561 agtgaactat cagtaaccca ggcctgtgcc ttggcatact ttccgtatcg tttatcaaga
     4621 ttacttgtct cagaagccgc atcatccaag agattcttgt attcatccaa gccaactttc
     4681 gccacaactt caggatcctt gccctttgtt atacctagat gtttcaaggc agaacccttc
     4741 ttagcatcta aaatattgag ataggttgct ggatcttggt aatctggtcc ccaacctgtt
     4801 ccgttcaaat catagtcttt ttgggttgga acttttgctt gagaagtaat actttccttc
     4861 tcattgtctg tcatttgaag aacatctata attacattct ccgttccaag tgtttcttca
     4921 attgattgtt ttagcgaatt ggtttgttga accgcaacta catctgtctg ttctactggc
     4981 acatccaaat gaatcgggaa acttactccc ttagcttgca attctgactt cgctttttca
     5041 aatgcagatt tagcctttgt aggattgtaa attgtatcct taccatctgt gagagtcaca
     5101 tctttccact gttctccata tttcagtagt tcatcctgag ccaactgtcc gaaggtcttc
     5161 cctgctactt gaacgtaatt atctggcact agactattac gaataatctt atccgcaccc
     5221 tcttcaccat ttaattgagc tgtataggcg tggcgattaa atgcaaaatt aagagcctga
     5281 cggaagttct tattgagaag agcttctttt gttgatgttt tttgtgactc atctgtttta
     5341 gctgttttat tgtaagactg gcggtttacg ttcacagtga ggtagtagct tgttgcctct
     5401 tgtggactat agacaatctt atcgccgtat tcctttttag ttgattcaaa gtttgagctt
     5461 gctggaaaaa gacgtgcagt ggtataggca ccttgtgtaa aactacgaat taaggattct
     5521 tgatctgaac catcatagaa tgttaatttc acattatcaa tcttgacatt ttccttatcc
     5581 caatagttag gatttttttc atattcaatc acagatttag aaatcaaaga tttcaaaaaa
     5641 tatggaccat tgtaaagaat acttgatgga gttggcgctc cgtaatcctt gcctgttgca
     5701 ttcaaaaatt cttcatttac aggaagcatg gttgcagtgg ttactttaga gttccaaaaa
     5761 ctttccggtt gattaagggt atattctacc gtataatcat caagagcttt cacacctaca
     5821 gttgagaagt cgtttgtctc accactaaca taagcctcca atcctttgat ggatttctca
     5881 accaaagaaa gaccatcgga ttttccgtct gctgcatgct ttaatccggt gacaaaatcc
     5941 tgagctttaa ctttcgcata ctcttctcct tctgaagtat accacttcac acctttacga
     6001 agtttgtagg tataagtcaa gccatcttta gaaactgacc aatcctctgc tagagaagga
     6061 atgagatccc catatttatc attctctaaa agaccgtcga cgacattacc tattacgtca
     6121 gaagttgaat ttttacttgt aacgctataa tccaaggatg atggatcaac tgcataaaca
     6181 taagaaaatg ttttgggagc atctgcattc ttttcacttt tcccacaagc tgttaaaaga
     6241 agggctgtag tcaaggtcac tcctgctcct aagagccact ttttcgattg cataggtaat
     6301 ctcctttaag atagtatttt cactattata ccctattttt ttataaatgc aagagctttg
     6361 atgcaatttg ttagaaaatt ctaacaaata tttaaaaaga tttttatgca caagttttag
     6421 taaaaaacct caaacttcaa aagcttgagg ccctctcatt ttatactcaa tgaaaatcaa
     6481 agagcaaact aggaagaagc tagccgcagg ctgtacttga gtacggtaag gcgacactga
     6541 cgtggtttga agagactttc gaagagtatt agtcagtcaa ttccacacag aaagcatccc
     6601 acggagctaa aatttgtttt tcaaagactt cttgagccgc agtgttttca atcaagaccg
     6661 atttgacgtt tccttctacg atcaagtctt gttcttcatt ggacaagtta gcgacgacta
     6721 ggaagcgacg gtcaccgtcc ttacggatat aggcaaaaac cttgtcagct gtttccaaga
     6781 gctcaaaatc agatcgaatt agccagctat tctccttacg gatttgaacc aacttctgat
     6841 aggtatagaa aatagaatct ggatttgcca gcgcttcttg aacgttgatt tcttgatggt
     6901 ttggattcac tgccaaccaa ggttgaccag ttgagaaacc agcgtttttg ctcttatccc
     6961 attgcatggg ggtacgggca ttgtcacgtc caatgacacg gatactgtcc atgatttctt
     7021 ccatcggaac gcctttttca agagcctcac gcgcatagtt gagggattca atatcttcta
     7081 cttgattcag tgttccaaac ggatagttgg tcatcccaat ttcctcacct tggtagatat
     7141 aaggagtccc tctcatgaga tgaagcaaga ttgcaaaggc tttggcagat ttttctcggt
     7201 attcttggtc atttccccag attgagacga tacgagggag gtcatgattg ttccaaaaga
     7261 gtgaattcca gccgtcctca actcctaact ctgtctgcca tttgttgaaa atttctttta
     7321 acttaggaat attcagttct ttttgatagt gccacttagg ctgaccttcc tgatactgaa
     7381 gaccgatatg ttcaaaatgg aagaccatag acaattcttg cccctttgga tcagagtaga
     7441 gcttggcaat ctctggcgtt gctccccagg tttcccctac tgtcaagaga ttcttatctc
     7501 caaaggtggc ctgattcatt tccttgagat aggggtgaag cataggacca ttattgacta
     7561 ccttctcgtc aggaattttg ccaatcatgt caataacatc catacggaaa ccaccaatac
     7621 ctttatcaat ccagaagtcc atcatctcat aaattttctg gcgaagtttt tcattttccc
     7681 agttgagatc cggctgtttc ttgctgaaaa agtggagata gtattgacca gatttttcat
     7741 cgtattccca agcagatcca ctaaaaatag aatctaaatc gttaggctca tcccgccaga
     7801 tgtagtagtc tcgctcaggg ctatcaggat tttcacaggc ttcaacaaac caagcatgtt
     7861 catccgaggt atgattgacc accaagtcca tgatgatacg aatatcacgc ttcttggctt
     7921 cctcaatcag ctcatccata tcctccatgg ttccgaaaat agccgcaatc gcttgataat
     7981 cagcaatatc atagccatta tcatccatag ggctgtcata aacaggagaa agccaaatcg
     8041 ctgtaatccc taacttggct agatagtcta acttactggt aattcctggc aaatcgccaa
     8101 ttccatctcc attgctatcc ataaaactct ttggatagac ttgatagact acggcattgt
     8161 gccaccattt ttcttgcatc ttcttacctc attattttca taatctacag tctatgatag
     8221 cgctttttaa aattttgtgc aagcgttcgc ctaatctttt tgattccttt tttaactcca
     8281 tagtttccta acttccaatt ttttattata atagaggtca gaggtaaaaa atgaaaaaac
     8341 aagcttttag ttctgaacaa tatttgaatc tacagcgcga ccacattttg gagcgcatta
     8401 accaatttga cggcaagctc tacttggagt ttggtggcaa aatgttagaa gatttccacg
     8461 ctgctcgtgt ccttcctggt tatgagcctg acaataaaat caagctcttg caagagttga
     8521 aagagcaagt tgaggttgtg attgctatta acgctagcaa catcgagcat tccaaagcac
     8581 gtggcgacct aggcatttct tacgaccaag aagttcttcg tttgattgat aaattcaatg
     8641 aattggggat ttttgtcggc tccgttgtca ttacacaata cgctggtcag cccgctgcag
     8701 atgccttccg taaccaactt gagaaaaatg gaattgattc ttatcttcat tatccaatca
     8761 aaggatatcc gacggatatg gatcacatca tttctcctga aggtatgggg aaaaatgact
     8821 acatcaaaac tagtcgcaac ttgattgtcg taaccgctcc tggacctggt tctggaaaat
     8881 tggcaacttg tatgtccaat atgtatcacg accaaatcaa tggtatcaag tctggttacg
     8941 ctaaatttga aaccttccca gtctggaatc tgccccttca tcaccctgtc aacttggcct
     9001 acgaggctgc cacagctgac cttgacgatg tcaacatgat tgaccccttc catcttcaaa
     9061 cctatggaga aaccactgtc aactacaacc gtgatatcga aatcttccca gtgctcaagc
     9121 gcatgttgga acgtattctc ggaaaatcac catacgcttc accgacagat atgggtgtca
     9181 acatggttgg tttcgctatt acagatgacg aggctgctgt cgcagcttct aaacaagaaa
     9241 tcatccgccg ttactatcaa accgttcttg atttcaaagc tgaaaaagtt ggcgaagctg
     9301 ccgtcaagaa aattgagttg cttatgaacg acctcggcat cacacctgcc gaccgtaagg
     9361 ttgctgtcgt tgcgcgccaa aaagcagaag aaactggtgg accagcccta gcctttgaat
     9421 tgccaaatgg ggaaatcgtc actggtaaga actcagaact ctttggtcct acagccgctg
     9481 ccttgatcaa cgccatcaaa aaatcagctg acatcgctaa agaagtaaaa ctaatcgagc
     9541 ctgaagttgt taagccaatc caaggtctta aaatcgatca tctcggtagc cgcaatccac
     9601 gccttcattc aaatgaaatc ctgattgcac ttgctatcac agctacagaa aatcctgatg
     9661 ctgcccgcgc tatggaagaa ctcggcaacc tcaaaggaag cgaagcccac tcaaccatca
     9721 tcttgactga tgaagacaag aatgtccttc gtaaactggg tatcaacgta acctttgacc
     9781 catactacca atacgaccgc ttatatcgta agtaaagatt tcaacctctc cagcctcgga
     9841 gaggttttct ctctgtctca ggagcaacct ttatgatata atgagagaag aaaactgaaa
     9901 ggatttacca tgtcaaaaga agttattgtc gaaagttttg aacttgacca caccattgtc
     9961 aaggcaccct atgttcgctt gattggggaa gaaactggac caaaaggaga catcatctcc
    10021 aattatgata ttcgcttggt gcaacccaat gaagactcta tccctactgc tggccttcac
    10081 actatcgagc acctcttggc caaactcatc cgtactcgta ttgacggcat gattgactgt
    10141 tcaccatttg gttgccgtac aggcttccat atgattatgt gggggcgcca caccagtgct
    10201 gaaatcgcgg ctgttatcaa ggattcgctc aaggaaatcg ctgagactac tacttgggaa
    10261 gaggttcctg gaacaaccat cgaatcttgc ggcaactaca aggatcacag cctcttttct
    10321 gctaaagaat gggcaaaact tattctagaa caagggattt cagatgatgc ctttgaacgt
    10381 catgtgattt aaacacaaaa aaggaaccag ttttttcagc tggctccttc ttttttattc
    10441 tcaaaattct gtcttaggat ttctcacgaa tgaccaaaac accatcttcc atgtcagctt
    10501 ctaggtgttt agcatcaagg ttatccaagt ggaagtctgt gactttgtca cggatttgtt
    10561 gttcaaccac acgacggagt ggacgaaccc ccatgacttc atcgtagcct tcttctgtga
    10621 tatagtcctt agctgcttga ctgactacca agtcaatgtc tttcttagcc aaggtttggt
    10681 tgacttcagc caacattaaa tccacaatct tagaaaggtc ttccttcgtc aagtgcgaga
    10741 actcgataac tgcattaaag cggttgagga attctggacg gaagaatggt ttcaaacggt
    10801 ccatcaattc tggtttgtcc gcatcttctg tcaagttagc ttcatagcca aaaccagcat
    10861 ttgatgttgc gataatgact gtgtttttaa agttaacggt atttccttga ccatcagtca
    10921 aacgaccatc atccaagact tggaggagaa gggtaatgac ttgaggatca gccttctcaa
    10981 tttcatccaa gagaatgata gagtatggat tgcgacgaac acgttctgtt aaggtattgc
    11041 tattgtcatc ataacccaca tatcctgctg ttgtaccaat tagcttagaa acagctgtgc
    11101 ggtcactgta ttcagacata tccaaacgga tgatcgcatc cttggttcca aacatatcta
    11161 gcgccaattg cttagcaagc tctgtcttac caaccccagt tggtcctaca aagaggaaac
    11221 taccgattgg gcgattgcct tcatcaaaac cagcacggtt acgacggatg gcacgggcta
    11281 cagcttcaac tgccttatct tgaccgatta ccttatcttg cagacgatga gccatatctt
    11341 tcaaacgctc gatgtctgat gctcccattt gcgatactgg gatacccgtc attcgttcta
    11401 cagattcagc cacatcgttg acacttgcag tcaccttcat atcttctgtg tggttttcga
    11461 ttttcttttc caactctgca atacgtgttt tatagtttag agctgcttca aaatcttctg
    11521 actcaacagc tttttcttgc ttgtcttttt ctacctcaat ttcacgttca acagcatgca
    11581 catctgttac aggatgctga gctgccaagt gagctgccgt tacatcgaca aggtcgatag
    11641 ccttatctgg caagctacgt tgaggaatat actgaacaga ataatccacc gctgctttca
    11701 aaacttcgtc tggcaagatg acattgtggt gttgttgata gaggtcacga attccttgaa
    11761 gaattttaaa agtatcctct gctgaaggag cattgacctt gacttcgttg aaacgacgag
    11821 caagggctgc atttttcaaa atagtgttac gatattcgtc ttgagttgtc gctccaatca
    11881 ctgtcaattc tccacgtgaa agagctggtt tcaagatatc agcaagacct ttagaccctt
    11941 gaccatcacc tgtgctacca gcaccaagaa tttggtgaat ttcgtcgaag aaaaggataa
    12001 tatttccagc ttctttgact tcgtttacca agttttgaat gttttcttca aagctaccac
    12061 ggtattgagt accagcttca agtccagaaa tatcaataga aatgatctct ttgttcttga
    12121 ttgctgcagg aacgtcaccg ttcacgatag cttgggccaa tccttctact actgcagttt
    12181 taccaacacc agcatcaccg acgagaactg gattattctt tgtgcgacga gaaagaattt
    12241 cagatgtttc ttgaatttcc ttgtttcgtc cgataacagg atccaacttg ccctcacgcg
    12301 cttctgctgt caagtttcga cccagtttag caaggacacc atcttgtttc atacctgacg
    12361 tatgttgtgg catttgtcca tcagcttctg catttcctgg taattgacca gtcgcacgat
    12421 agtgagcaaa ttcctcaggt gtgacttcac gtccattaat caagtaacga cgattttcag
    12481 aactgtatcc gcgcatacca cccatcaatt ggttaaataa atcatccatg ttgttaaaat
    12541 tattaaagtt gttgttcata ttctttacct ctttttgttt acttagttat gattactgat
    12601 attgactatc tttgaccttt gttttaaaaa atttagacta gctaaatcgc tactctaggt
    12661 actatttctg gtttttcttt ttcaagcagg agtagactat ctttacttct gaagatttct
    12721 agattaaaca tagacacacc tctttctatt ttactttaaa taagtgttca cgtaaggctt
    12781 tcatttacct tacgttcata atatactaca ttagtcagaa aaggtcaagg gatttgactt
    12841 taattgacca atatttttta aaaagcaaaa acaccctgaa acatcagggt gccattctta
    12901 catcaaatac aaaattgcta gggtcaagag acttgctaga agtcccactc cccaaaagaa
    12961 gaagtcaacc ttccactcgc tccatggatt tcctttacca gacaatcctc caagctcaaa
    13021 atggtgatgc acaggcgtca tgcggaaaat acgtttgcca ccagtcattt tgaaataact
    13081 gacttgcatc atgactgaag ttgtttcaaa aacataaaca attccgataa tcaagagagt
    13141 ccattcttgg tggagggcca tagagatagc tgccagcatt ccaccgagag ctaaacttcc
    13201 cacatccccc ataaagacct tagcaggctt atggttaaag acaaagaaac caagcaaacc
    13261 accaatcatg gcaagaatca ctagaaggat atccatctga ccttgcacat aggcaataac
    13321 tccataggca gacaaactaa tcacgactga aatactagcc agaccgtcaa tgccgtcagt
    13381 caagttgact gcgtttgaaa aaccaactag ccagaaaagg gcgaaaagaa tatagaaaat
    13441 ccctagatgc acttggtaac caaagactga aagcatatcg cccccacgct cataaaaaag
    13501 gtagaaaatg acgccaccta gcagctgaag agccaatttc tgtttggggt ttagcccctc
    13561 attgatcttt cggaagacct tgagaaagtc atctaaaaaa ccaaccaagc catacaagac
    13621 caaaataaac aaaatcatac caacattatt ggtcaattgt ttcgaaaaaa gagcgacgag
    13681 gaaactcacc acaactgcag caatgaggaa aacaagtccc cccattgtag gagtcccagc
    13741 ttttgcctgg tgctgtttaa catcctcatg catctgctgg cctgtaattt gcgcctttct
    13801 ataaaattgg ataaaggccg gaattcctac taaagttagt aaaaatgtca caattccagc
    13861 actaatagaa ataaacatat tagtctccta aagttaattt aattttttta atgtttttga
    13921 tagctgtatt agtccgaaca tcttgcttct gaacaacgga acctgaacct tcaaattcca
    13981 gttcaatatc caaccattta gcaaaggtct cggcagtctc ttttttccag ccatacatgt
    14041 ctggaatttc ttctacctta tccgataaaa ggagaacttg ttggtttggt gcaagattgg
    14101 tcccttcttc tacagaagtc tctttaatct ttgttccagt acctacaacg attggttgca
    14161 caatatttcg gcgtaaggct tccgccaact caccaggtga aatatccttg atgctaggca
    14221 ttgcataaga agattctgtc gtaactttat ctaaattttt ggctggagat tgaagattga
    14281 gagattcttt catagctgaa gcccgctcca agattggggt ggcaaattct cccaactgga
    14341 tacctgaata atgctcaggc tgttgaaccg ttacatacaa gataaaatca ggattttcag
    14401 caggattcat agtcacagct gagaaaatat aattggtaga accaaccaag tatcctccat
    14461 ttttctcatc agcgatttga gccgtaccgg atttaactgc tacattttgt ccaggaactg
    14521 ttataattgg ctttcctgtg tagtgattat acatagttcc atatagaggg tccgtcccaa
    14581 ctaagatcat gtgatttcga gttgtgcttg ctgcctcttt ggaaacagga tttcctacta
    14641 tttctttttg tgacttacgt acagactgat tgttagtatc ataaatagca cttataaatt
    14701 ttggctccag cataactcca tcattagcaa tagctgtaaa ggcacgaagc atttgtgttt
    14761 gtgtcactga aattccttgc ccaaatgagc tttgagcaat actaacaata ttatcagctg
    14821 gaagttgacc agcgtattca tctgtcaagc caaagcgagt tggaacccca aatttaaagc
    14881 gttttagata atccaaccaa gtagcatctc ccattttttg ttcaagtaga ctcattccaa
    14941 cattactgga gtgagcgaaa ccttgtaaga aagtcatcat cccaccagta gtcaaacctt
    15001 cattaacatc ccaatctcga gtcgtcgcat ccgctatttt gaattcactg ctattgaagt
    15061 attctccact tgggaaggta ttattatcaa tagaagaagc taacgtcata accttcatgg
    15121 ctgatcctgg ttcatagtta ctttgataaa gaatatcacg ccaaacaaag tcctcagtga
    15181 ttccttcttt agtatctgca ttaaaggtag gtcgttgggt ggtagcgagg atttcaccgg
    15241 tctttgcact gaccaaggtc gcggtcatat acttaccttt tactttttct agaaaggcat
    15301 ccatctgagt ttccatgaag gactgaaggg tgctggaaat agtcgtataa acatccttgc
    15361 catctactgt ttgctgggaa acttgttctg ttccagggac aatattaccc agacgatctt
    15421 tttcataggt aataatgccg tctgtccctg caagaattct atttaaagaa ctctccattc
    15481 cagaggttcc cagcaagctc ttgctgccat cttcattttc atggagctga gctagaccga
    15541 taaaactaga agcaaattgt ccgtttggat aactacgatt gggactggtt gtaaaatcaa
    15601 tccccttgac ctctgcagtt tccaactctt ttttaatagc catcatattg gcataggtaa
    15661 tcccattgcc cttcgaacca aaggaaactt gcttgagatt aggttgcgag agttgctctc
    15721 ttacatagga ttcttccatg tccagatact tatgaaagac ctctgcaacc ttgttaaatt
    15781 gtgttttttc tacgtaaaga atcttacccg ttgctgactt atagttctca tcaatgaccg
    15841 catagacatt ataagatgtc gcatcctcag caatcgggac tccatttcgg tcataaatag
    15901 tcccacgttt ggcaggaact gtacgggtgg tttgatgaac cttcttagct tccttcgcta
    15961 aatctgttcc aaagcgagtg cccgtcccaa taatgaccgc aaaattgact aaaaaaacgg
    16021 caaaaacaaa gacagataat aaactcagac tttttccaac tctgcgtctg ttttcagccg
    16081 gcgatttcct atttttcgtc gcataacgga ttactttttt tgtccacttc atatcttact
    16141 ccgctattcg aatattttca ttgtttaatt gcaaatcgtg tgaattggca atttctttca
    16201 aacgttctgc acgtaatagt tcattgacct cttgcttggc atcgtccaat tcggtcttct
    16261 tttcctctat ctgcgcattg atttttgtca aatcattctg cacttgcaag agcttggtct
    16321 gcataaaaat aatactaatg gctacaataa gagtggttac agcaatggaa aagtaaaaag
    16381 ctttttccac acgcgaaaac cgtttaagtt gcatctgtag tatttgacct gttttttcca
    16441 ttctttctgc catcattttt cctcttactt gtgaattttt ctggccacgc gcaacttagc
    16501 tgagtgcgag cggttattgg cttctaattc ttctgcactt ggcaagattg gcttacggga
    16561 taccaattcc atcttgggct tgagatcatc tgggatgaag ggtaagcctt ttggaacttc
    16621 aaccgttgaa gcttccttga acaattgctt ggtcaagcgg tcttctaagg aatgaaaggt
    16681 aatcactgaa attctaccat ccagagccaa catctccata gcctgctgga tggactcatc
    16741 tgccgctccc agttcatcat tgacttcaat tcgaatagcc tggaaaatct gcttagcagg
    16801 atgacccttc ttcttgagtt ccttggcagg tttggccgac ttgataattt ctgccaattc
    16861 agtcgtagtc tcgactggct tcacttcccg agcttgttca atcttacgcg caatctgttt
    16921 agagaatttg tcctcgccat acttgaagaa aatacgaacc aagtcatgat agtcataatg
    16981 gttcaccact tcataggctg tcagactagc atcctgattc atccgcatgt ccagtggcgc
    17041 atccttttta taagaaaaac cacgctcacg ctggtctaat tgaggactag acactcccaa
    17101 gtcataacaa attccatcaa tttcctgaac accagcttcg cgcaaacgtg cctgtaaatg
    17161 acggaagtta tccttgataa aagtcaccat ccccttttca atgtagggtg ccaagcgttc
    17221 ttgcgcattg tcaatggcat tctggtcctg gtcaaaggca tagagatggc ctttttcact
    17281 taatttactt aataaatatt cgctatggcc tgctccaccc aaagtcgcat caacgtagat
    17341 accgtcaggc tttacgtcga gcatatcaat cgtttcgtgg agtaagaccg ttacatgatg
    17401 aaattctttt gtcatatctt atctatttta ccacaaatct gactagcttg cactagtcag
    17461 acaaataggc caaaaacaag taagatttct ttaagaaata tgtcaaatat gcttgacatt
    17521 ctctctatag aagactataa tatagtcaaa tatatacgac ataaatcaga aaggagacca
    17581 gatgaatcgt gtgaaagaat ttcgcaagga actgggcatt tcccagctcg aactcgccaa
    17641 ggatatcggt gtctcgagac agaccatcaa tatgattgaa aacgacaagt acaatccaac
    17701 cctggaactc tgtctcaatc tcgcccgcag cctccaaact gacctcaaca gtctcttttg
    17761 ggaggaagat ttttaaaaaa ggagccaact catgaaaaaa gaaaccttca ctgaaaaact
    17821 catcaaacgc acatacggta tttctggtcc ccttgacgaa tacaaacggc gtgaggccga
    17881 tcgtattggg aaccaagtct ttatcgtcct cttttatctg atgattttcg gaaatcttat
    17941 tccactcctt ctggcctata aataccctca agaagtggct ctaatctatc ctcctctgat
    18001 tttagtgatt gccctcatcg ctgctggcta tgtcacctac caaatgaaaa aaacagggat
    18061 tacagctatt gatccagatt tgctgagcga gaaagaaagt aagcaactat actacccagg
    18121 tctaaaagca ggtttgttct ttggtctatg gatgtttttt ataactcctc ttctcagtat
    18181 actcataggt gaaggtcagg actattttca ttctctcctc actataagaa atggtgtatc
    18241 aagcattctc ggttctatct tcttcggagc gagtatacag ttcctcatct cccgtcgcat
    18301 tgcaaaagct aagaaagatc aagatgagga ttaggaggta cctatgaaaa aagaaaagaa
    18361 acagttacgt tatcctggtc taaaagcagg ttcgatttat ggaacagtga tattttttat
    18421 aattccactc attgataccc tcacaagtga aaattcaaat tttattagtt ctcttctaaa
    18481 tacaaaacat attttcaaaa ctatactggg agctttcttt ttcggagtga tgatgcatat
    18541 tgtcgactca cttcgtattg caagagctaa aaaagaccag gattaggagg tgccttatga
    18601 aatcactagt aactttactt acctatcatc ttttgttcag ttctctgctc atcttcatca
    18661 tcgtttcagg gaacttgcca atctacgata tagtcctcct tccagtcttt gttccagccc
    18721 tcaacaaagg actgacttat ctaaagattg actccccaaa aacgcgcata ctcaacttag
    18781 cactgtgctt tatgattcta tctttaccac aactgatgct catttcaagc gattggaaat
    18841 attatttact gctgactatc gctagccttt cttccatcac ttatctttat tatctctatc
    18901 aattcgtaaa agaaaatcag taaaaccgct catttaggag gttactagca tgaaaaaaga
    18961 agacttaacc actcgcctac tccgaaatct ctttcatatc caaggtcctt ttgatgaatg
    19021 ccgacaagag attatctaca aagcttgtgc ccgtttcatg gtccaaatcg tttattcttc
    19081 cttctttctc ttcttgtttt atctattatt tggacgcttc atagaggtgg ttcgctatgc
    19141 tatgccctac gtttgctttg gactcatttt tttcattact ttaaaaactc aaagagccgt
    19201 caaagaactc catctggaaa aagatgacaa gtcagaaatc attctcaaaa cctacagcaa
    19261 agcccaaatc aaatttcgaa gctggattgt gtttatcggt cttcagattg gcctctttac
    19321 cttactcatc tttcataaag tcttcgttca gcagatgtcc ttttcagatt ttgtgaagtt
    19381 gctcatgcaa ttcgataaaa gcgttccttt cctgatgtat ggcctgatta tcggcagcat
    19441 ttttggaacc ctgacctacg gctttctatc attacaggag gagaaaactc ctaaaaatac
    19501 caaacagaag gagaaaagca atcaatgacc tcactatacg atttttcagt cttgaaccaa
    19561 gacaatcaag aaaccccatc caatggaaat ttccaatatt cctagtcgta accatcatct
    19621 caagtttggt ctacttctat aacttttatc aagtagttaa agaagtaaat caaaaacagt
    19681 tgatttagga gattactccc ataatttctc attttataga caaataatcc catccagctc
    19741 atgctagatg ggattatttt atttcttaac agaggttgcc agttatttcc ctttcatctt
    19801 agaaagtcga ctctttccaa ctcacactac aatccaagac ttgttgcctt tcttcttgat
    19861 tgaggccttc aatctggtca atcaaaatct ttgtagcctg ttgtccttct tcaaaggcgg
    19921 gctgaaccaa cgtcgaaaca cttggagaag aaaagcaagt ccactccgta ttgtcaaaac
    19981 caatcaaccc aacttgtggc aagttataat tcaactcttt gataacggta aagactggag
    20041 gtagggccca acagttagga acaaatacca gagttttttc atcgggattg atttcttttt
    20101 gtaaaaattc cttaatttgt tccaaattcg tatgcttatc ttcaatggtt agcctagcgt
    20161 ggcgcatatt agcatctgtt aaagcatcca caaaaccact tgcccgctca atccgagtac
    20221 tcaaacgact cgtatccgct gtaatcaaga gaaaatgctc ataacctttt tcgatacagg
    20281 actgggtcat atcataaacg gcatcatagt tattggtttt gacccagcta gttcggtgtt
    20341 catagagccg actatcaaaa aagaccattt tcttcttttt ctcatcgatg atacgagaat
    20401 attttcggaa attagaggta ggctgaataa taaagccgtc tactcccaag agaagcatgc
    20461 tttcaatata cctgtcctca ctctcttggc tgtagttact atttcctatc attacctggt
    20521 agccactctg gctggcgata tcctcaattc ccttaacaat ttgggttgag aaactgttgg
    20581 taatatcacc aatcaaaaca ccaattaatt ttgttcgttt ggagtttaag ctacgcgcaa
    20641 caatgctcgg tttgtaattt gtttcatgaa taactttttt aatcttttca cgtgtctctt
    20701 gggacatttt ttcatatttc ccgtttaggt aaaatgacac ggttgttttc gaggtctgag
    20761 ccatttctgc aatatctttt atggtcagtt tcttctccaa tctaaaacac ctcctactaa
    20821 tatccattat aacatattca ctattcaaaa catctatttc tagcactgca agcgaatcat
    20881 tctctcattt attttatcat atactagaca ttttccacgc atttttgttc cgtcaacgag
    20941 gcataatttt tcacctacac aaatatcctc gcttaataac agaatcagct tgtctgtttc
    21001 gtcatttttc acttcaaaag ccagagcatt ttctacttga tgaccatctg tctggtagac
    21061 agaatgacgg atgatttcaa aactctcatg cgcaatgatt gtataatcca gcatctgatt
    21121 ctcaaagaat tggtgtttga tgagtttgct acttttttca agctcgttgt atttaggaga
    21181 aatgatggta tcttccaaat caaaatcaac ttcactccat agtttcaact gattgatttt
    21241 cccatcttga taggtcacat ccttgtcaag gataaactga gtcaacgcct catgctgacc
    21301 ttgacacctg atatcatcta ccaagagcca tacatcctct gccaacatga ggatttttct
    21361 cctgtgaaga taaggcaaat caggttctgc tgacaaataa gccccctcaa tataatgcac
    21421 tccctctctt tctttgtggt gacagaacag ggagtgagga tagtattcat attcccagga
    21481 tcccacgatc ctttctggag ctttcccatc tactatacag gtcgaatgac tccaagcact
    21541 ctttaagaga taacgttcat caacctcccg ataagaataa cgcccagcat ctatgaaaat
    21601 cggttggcct tgatactgta agcaaaaact attctcgtca ctatggctat gggcacttcc
    21661 cagcggaccg tttttaaaaa atagataacg atgttcatcc ttaatgcaaa catgcccaga
    21721 atcttcaaag ctcctgaact taggctgcca agctctcttt tcaaattcct gcagtcgctt
    21781 gaccttttct cgtccgagga acaggaggct aagcaaatcg actttaacat ccagaccgtt
    21841 aagaaggtct tccttgttca aaaccatagc agacaggctc aaaatctctg tcgtttctgt
    21901 agaatcgcta tcaccaaaag ccaaggtccg tccatctaga cctgtcatca tttgaatgta
    21961 agttgccatc ttttccagca gctcttgaaa gctatcttgc aagtccggaa gcaagagaca
    22021 taagtccagc aaggctttat aaacctctac atgatagaga atcgactgtt caaactggct
    22081 tccatcttct aaaatctgcg tctcgatctg ctgtttcaac tcctttgaag caaaatggta
    22141 agcttcttct aggtccatct tatctgaaaa gaaatgatag gttgcaagta tcggaatcgt
    22201 ttgtaaaatc ccccagttac taagggtgta cttggcgcga taatggcttt tcataaagtc
    22261 aatctgcttt tctagactga ccaaaatttt ctctagttct tcctcctcta gcaagtcaaa
    22321 tttcaagagg agcaagagta gtttcaacca agtaaaggaa cgaatacccg tatccaaggt
    22381 tctagtcatc aaagattgag gacgaaattc tctcacctgc tcaatccagt caaatagaaa
    22441 gaacttgcac ttttgaatat agcccttatc tccttctacc agatacccta tcataaactg
    22501 caagagatat tcttgtcgat tgagcatata agcccattct ggatcatctt caaatacttg
    22561 attccacacc atcggctgga tttgatggat ttttgaacaa ggttccatat cccaaggact
    22621 atcaaacata aaacgattgt ccatcaagcg ctcaagggaa ctcttgactt tctcatagtc
    22681 ttttgaacag cgggacaaga tataatcacg atattggtcc ccatcaattc tttcaaaaaa
    22741 ttgtcttctt tcttctttca ttatctatta ccagaaaaag aactacttaa aaagcagttc
    22801 ttttgtcttt cccattacac tttccttttc tacatagatg accacacctt ttgcaatctg
    22861 caaggagacc aagtcatctt tgatagaaat gatttttcca tgaattccag acaataacaa
    22921 cacttcatca ccagatgtta aagaagctaa atactctttt cgttgctcca tctgtttgcg
    22981 aagcaacttt tgctgacgaa tagaatgaaa gcttgacagt aaaagggggc tcactgccaa
    23041 gacaatcact attccataaa acaatgttgt atccattaag ctagaatctt aagccagctt
    23101 ccgataattc cgatgataac tgttaaaata acgagtttat atgttgtcca tttcttttct
    23161 ttgatcaagt agtaaactaa aagtgtaaat agggctggta gaagagctgg agcaacctta
    23221 tcaagcattc cctgaatact tacgatactt tgtttagcgt ctgctttaac ttcccctgca
    23281 gcaaaggtaa tcggcaccat aatcttaaca gatgtcgctg ccaaaccagc aattacggtt
    23341 acaccgataa tattagcaat acgagaaatc gttgccatct gttcacttag tttatcaatc
    23401 acagtcgttc ctagtttgta tccatagaga ccagttgaca atttaatcgc tgtcaaaatc
    23461 gtattcatcg ctaggaagaa caagattgga ccgacaacca ggccttcttg agcaaaagaa
    23521 gcggcgatgg ttgagaacaa tggagctaaa cagaattgag aaagagaatc cccaatacct
    23581 gccaatggcc ccatcaaggc catcttgatg ctacgtgtct cttttgccgg acggccattt
    23641 tccaacatta caaggtgcaa actggtaata aaaggcagga agtgtgggtt ggtattatag
    23701 aattcacagt tttcttccaa ggcttggtag aaaccttcct gatcctctcc atagtgtttt
    23761 ttcaaagcag gatacatcac attggcatat cccaaccctt gatagttact atagttaaat
    23821 ccattttgac aaaagaatgc ccgcaaagac gttttaagat aatcacgttt tgttaatttg
    23881 ttagatccag tcatcgtgtg cttcctcctc taccacatga ttcgctgttt ttggcttgtt
    23941 ataaaattca atcaaagcaa agatagtacc tacaattgca ataccaattg ttgggatgtt
    24001 tagataagct gcacaaacat atcccaacaa gacaaaggga atcaactctt tcttagccat
    24061 cactgacaag atcatcgcaa aaccgatagc tgggagcatt ttaccagcaa ctgtcaaacc
    24121 tgtaagcaat accggtggaa tgtagtctac gagtttcaac aaggtatcca ttgaaagggc
    24181 acccaagcaa cccaaggtaa atccaataaa ggcaaacaac caaattgttg catttagagt
    24241 gaacttgaat ttcttcaaat tatggttttt caagtgcttc atcgccgttt caggcgcacc
    24301 agcacgtaca gtgtaggcga aagtttgtaa gaattgaatc gccacagcaa tcggagtaga
    24361 gagggcaaga gccgcttctg gactgacttt accagcacta gtgatagcca tcaaggtacc
    24421 aaagatacca ggtccgattg ggtttggtgg aacagtacct ccagcaccaa caccgaatcc
    24481 catataagcc aattcaccaa tagctcccat tgcaagagca gtaggcaaat cacctagaat
    24541 aattccgaca ccaaatgaca gaacaataca tctattggtg taaattccta acagcattcc
    24601 actaaaacag aaagctgtcc ataatccaat taaaatcgct tgaaatacat taatcgacat
    24661 aacgatctcc tcttttaaat atagtccata atgttgactt caacagctcc atcatttcct
    24721 gttggagttg ttttcgtatt aaatgttact tgataagttt ggttcaattc cttgagggct
    24781 gccttgtcct cttcacccag gaagatggag cgtgtcactt gctctttacc aggggcattg
    24841 tgaatgttcc caatattgat ttcttcaata gggacaccac cttctaccaa ggttaaagcg
    24901 tccttcacat cctttacaac gataaagatc gtttgagcag gattagcctt gtgaatgata
    24961 tcaatcacct tttgcaaagg gaagaaacgc atggcaactg agtctggcac aactgttttc
    25021 atcagagttt gttgcatctt gtccgtgctt acttcatcat tggcaacaat gaccgtatta
    25081 caacctaggt attttaccca aagttgtcct tgtccatgaa tcaaccgttc atcgatacgg
    25141 gtcataataa tatttggcat tgtcatattt ctcctcctac caatataggt tccaatcctt
    25201 gtagaaacgg ataagggctt ctaggtaata gtagtcaccc cagatattgc cttcgtccac
    25261 tcctttacct gaatgccatg agtacacacc gtggaggaga cttgtcccac caggggtaaa
    25321 ttgatcattt gcataatgtt cgatcaaaga acgaagcatg gcatgcatag catgtttata
    25381 aatatctttg tcagcatcca cctctgggag atgttttagc atttcatgaa tcccacagac
    25441 agcgatagct gttgctgaag aatctcgtga ttgatcacta ccatcattaa aaatcaaatc
    25501 ccaataagaa acatgatctt ttggcagacg attcaagaaa taattggtta cacccttaaa
    25561 caagttaaag caggactcgt ctttcaggtg acgataagtc aaaggaatac catagactcc
    25621 ccatgattga ccacgtgccc agcatgaatc atcactatac ccttgtctcg ttacaccttt
    25681 aaagggttga cctgtctcag gatcaaaata gaaggtgtgg aaggacgaag cgtcatcacg
    25741 gattacatta ttagctgaag catagaaatg gctttctgca atatcgtagt atttttgatc
    25801 gcctgtttct tgataagcaa agaataagag ttggatattg agcaagcagt cgataatcaa
    25861 acggtaatgc tctttcttgc ccaagtctcc ccaagcttga ataaaaccac ctttttcttg
    25921 atagcgttca atcaacttat ctgcagcttt caaggctgct tctctagcct ctccatctcc
    25981 atttatctta tattcagcca tacaagacgg tgtgtacaag aagccgagat catggtgagc
    26041 caattctact ctcttattga cacgatccag gaaagaaaga acatttttat gagcgatgtt
    26101 tttaaatgca tcctgttgac tgtattcata agccaaccac agttctcctg tccagaaacc
    26161 attggtccat tccgtgttat ccatgattgg atagacatta tcaaaggtag ctggcgtcgg
    26221 gaaatcttcc ttgaaatagt caaggttgag ttctaactgc cgaataacct tatcgattgc
    26281 ctggccgact tcttctttcg tcagaagtgg tacttctaag aagcactcag gcgattttat
    26341 tttttcaatc gtaacctttt ttatcattct tttacccttt aaatacccga ttcgaaatct
    26401 tcttcctctt cctctgcatc cgttgaaaac aattctttac catttacaac tccgccctgg
    26461 gccgccacta ctgatttatt aacaacctca tcaaagctat gagccattct agcaaagact
    26521 gcttccatta acatggctaa gttcaaaccc gagagaacat tcattgtttt ggctggattt
    26581 tctcccatta tggtagaaga aaccttgaat ggcgatcctc ccaagagatc acttaggatt
    26641 aaaacttctt cttcatttga aattgcaagt aagatttttt gcttgagttc atctgctgac
    26701 attccttcca caaagtcaat cgcctccaca ttttcttgat tgcctgcaat caattgtaaa
    26761 gaactataaa tccctgtggc aaaatgtcca tgccctacaa gtacaatttt catcttttct
    26821 cctttctttt ttgagtttac cggtttactc tatattttac attgtagacc tttattttta
    26881 tcttgtcaat agttttttca aaaaaatatt agcgctttca ttgcttattt aaccattaca
    26941 atagacagaa acttcaaaat cttccgtttt tttaggaaaa caaagatttt cagaaataaa
    27001 aatatttaat tattgacaaa accggtttac tagaatataa tttggttata gagaagtctt
    27061 aacaaatttg aaaggaagta tcaaatgaca aatacatcat tctcaattga gcagttttct
    27121 ttaaaaggaa aaattgctct catcaccggc gcttcttatg gaattggatt tgctattgcc
    27181 aaatcctacg ctgaggccgg cgctactatt gtctttaacg atatcaatca agacctggtc
    27241 aataaaggga ttgaagctta tcgtgaagtt ggcatcgaag cccatgggta tgtctgtgac
    27301 gtgacagacg aggacggtat ccaagccatg gtcaagcaaa tcgaacaaga ggttggtgtc
    27361 attgacatcc ttgttaataa cgctggtatt atccgccgcg ttccaatgtg cgaaatgagc
    27421 gccgctgatt tccgtaaggt catcgatatt gacttaaacg caccatttat cgtttcaaaa
    27481 gcagtcattc cttctatgat aaagaaaggg catggaaaga ttatcaatat ttgctcgatg
    27541 atgagcgaac tgggacgtga aacggttagc gcttatgctg ccgctaaagg cggcttgaaa
    27601 atgttgaccc gcaacattgc gtctgaatac ggtggagcca atatccaatg taacggaatc
    27661 ggaccgggtt atattgccac tcctcaaaca gcacctcttc gtgagttgca agaagatggt
    27721 tctcgccacc catttgacca gttcatcatt gcaaaaacac ctgctgcacg ttggggaaat
    27781 cctgaagatt taatgggccc tgctgtcttt ctcgctagtg atgccagcga ctttgtcaat
    27841 ggccacatcc tatatgtaga tggcggtatc ttagcctaca tcggaaaaca acctgagtaa
    27901 aaatagaaag aggatcttat gaaaatcgca ttaatcaatg aaaatagtca agctagtaag
    27961 aatcacatta tttatgatag tctaaaagaa gcgacaaata aaaaaggcta ccaattattt
    28021 aactatggta tgcgtggaga agaaggtgaa aacccattaa catacgtaca aaacggccta
    28081 atggctgcca tccttttaaa tacaaaagca gtcgactttg ttgttaccgg ctgtggtacg
    28141 ggtgtaggag ctatgcttgc tttaaacagc ttccctggtg ttgtctgtgg tctagcagtg
    28201 gacccaactg acgcttacct ttattctcaa atcaatggtg gtaacgcctt gtctatccct
    28261 tatgccaaag gatttggctg gggggcagaa ctgaccctca aattgatgtt tgaacgctta
    28321 tttgctgaag aaatgggcgg tggctaccca agagaacgtg taatccctga acaacgcaac
    28381 gctcgtatct taaacgaggt aaaacaaatc acctacaatg atttgatgac catccttaaa
    28441 acaatcgacc aagacttcct caaagacacc atctctggca aatacttcca agaatacttc
    28501 tttgaaaact gccaagatga tgaagtcgct gcttatttga aagaagtatt agccaagtaa
    28561 agctattcta aaccagaaag gaactaatgg atgacgaaaa tattactgtt tggcgaacca
    28621 ttaattcgaa tctcaccatt agatgccacc agtatcggcg atcatgttgc cagttcgact
    28681 tattttggcg gatcagaaat taacatcgct tgtaatttgc aggccctggg tatctcaacg
    28741 aaagtcttta ccgcactccc tgccaacgag attggagatc gttttctcac attcttgaaa
    28801 cagcaccaaa tcgataccag ttcaatctgt cggcttggcg atcgaatcgg cctctacttt
    28861 ttggagaacg gctttggttg tcgtcaaagt gaagttttct acgatcgtaa gcatacgagt
    28921 atcagccaga ttcggccaaa catgctagat atggattctc tctttcaggg gattggccat
    28981 tttcatttta gtggaatcac tgtagctatc ggtcaagagg ttcgtacgct ccttctccta
    29041 ctcttggaag aagccaagcg ccgagggatt atcgtttcaa tggatctcaa tctgagaaca
    29101 aagatgattt cagtcctaga agccaagtat gaattttcta agtttgcacg tttcgctgac
    29161 tattgctttg gtattgatcc tctcatgatt gatgaccaaa atctagagat gttcccaaga
    29221 gacagagcca gcctaaaaga ggtggaaaat cgcatgcgac aattaaaaga agcctatggt
    29281 ttcaaggcca ttttccatac cctccgctct agtgatgaac aagacaaaaa tgtctatcag
    29341 gcctatgctc tgggagaacg atttgaagag tctgtccaac taaaaactgc agtctatcaa
    29401 cgagttggta gcggggatgc ctttatatct ggtgcccttt atcaactact ccatcattcc
    29461 tccttaaaaa ctaccattga ctttgcagtt gcgagcgcaa ctctcaaatg cactcttcca
    29521 ggagaccatc tctccacttc cgaaactagt attgaaaaat tactggcaaa tgcacaagat
    29581 atcattcgtt aggagaatta catgaccaaa tcagatacga ttattgaact aaaaaaacaa
    29641 aaaattgtcg ctgttattcg aggaaataca aaggaagaag gactgcaagc ctcgattgct
    29701 tgtatcaagg gaggtatcaa agctattgaa atcgcctata ccaatcagta tgcagggcaa
    29761 atcatcaagg aacttgtaga cttgtatcag gacgatcaaa gtgtttgtat cggtgcaggt
    29821 actgtgattg atgccgtaac tgctagagat gctattctag ccggagcaaa ttacgttgtt
    29881 tctccatctt tccatgctga aactgcaaaa atgtgcaatc tctacagcac accgtacatt
    29941 ccaggctgta ttactctcac agagataacg actgcacttg aagccggtag tgaaatcatt
    30001 aaactcttcc caggtagtgc tctcagtcca gcatatatct ctgcagtcaa ggcaccgatc
    30061 ccacaagttt ccgtaatggt aaccggagga gtcggcctaa acaacattcc tcaatggttc
    30121 gctgctggtg cagacgccgt tggaattggt ggcgaactca ataaactcgc ttcccaaggc
    30181 gactttgacc gcattagcga gattgcccaa cagtatgtta cactcagata aaatgaagtg
    30241 aaaaaaatcc gaagatgttt gaccttcttc ggattttttc tattttccac agtttcatgt
    30301 gattcatctt agatgatgaa caaatcagtt attctttcct ctacggaata gataagccac
    30361 cccaagtagc aataacccta gacttgccaa gattgactga ccttctcctg tctgagggag
    30421 attcttttga tccgaatggt tcttttcttc ttcagatttt tccttttctt ttgaatcctg
    30481 agtttgtggt tgagctgctt gttctaactt tttaaagact tcctgatctg gagctgattc
    30541 ctgtgtttca ggattgtagt aggcaacctt atagtcatcc ccttcttttc gaatggtata
    30601 gaccccacgt ttcaagactt ggaattggtt ggaaatagta gagacagaat catcatattt
    30661 cacaatgccc caaactcctt gtttggcatc ataaacagac tgaagggtct cattgttatc
    30721 gatgagacta ctttctaact cttttaccat ttgattgaag gtggcacgat ccacgttagg
    30781 gatgagcata tagccataag aatccccatt ttacttatga gcctgactaa tcgtaagaaa
    30841 ttcattttca acttccttgt ctgactgtcc ttcattgata tccttccaag atcccttttg
    30901 gacagcctta ctcatactga ttgaactctt cttaaagaaa aagtaaccaa tattcttttt
    30961 cgaatcggac gattctaaga agacactttg ggtttcagga taatcctttt cttgttccgt
    31021 gagggaggct tctttatcat tgacatagac tttatatgga acacttgatt ccagttttct
    31081 ctggtcaatt gtagttgcag cagtatctgt tgaagtgttt tggatattgc ttcctaaaaa
    31141 ggcgatctta tccttcagta taaaccagct cttatgagca gtcagtgttt gattccagtt
    31201 agtgaaatcc atggttgctg tcacattggc ctcatctagt ttgctcgttc caacgaaagc
    31261 agacggtaga actttacctg tatcactatc cgatctctta gcatctggct ctgtcgtacc
    31321 aggcatctta tatggattaa ctgttggcca gtagccatcg ctatagtgac tcaaatcgcc
    31381 attgtaaaga tagaacatcc catcactcgt ataccaacca cgtttgtttt ccttgttcat
    31441 gtgttcgtaa ttcaagatat gactggaaaa gagtgacaag ccaaatccaa accctttctc
    31501 tgcattgtac atggctgttt tatccatctt attaaaggca gataggtaac tggttcttgg
    31561 aacacttgcg actccagcat cgcttaacaa agattgcatc aaactgatat ccttataagt
    31621 cttcaaattc ttaaagacat cataataact atccgattga acaatggtct tcacaagact
    31681 ctgcaaacgt tgtttggttt ctccttcaga catatccgct atccggtgaa tccctcttgg
    31741 cacttctact acggccacgt gcccctcgca atttgcacga ctgatcgagc gtccacgact
    31801 catatccatc aactctccat tcaccagcaa aggggcaaac gatttatcaa tccagtggta
    31861 catcgtttgc attttatctt tattgattgg gctcttggtc ttttgaatga ctggcaacag
    31921 ttgagacagg ccatcaatca agacatcccc ataagcatcc gtataggcaa cattggtgtg
    31981 gtcaatatag aatccatctt gataaaaacc ttcaccttgg tctaccaact tgaacacttg
    32041 ctcaatcgaa cgaatggtag aagaaatttc ttggtcatcc ttacgcagta aaccagctat
    32101 tacttttacc cttcccatat ccactaagtt tccacctagg gccttaaatg ggttatcagt
    32161 cgtctttcgg aaatgttcgg gatctggcgc aaatttttca atcacatctg tatatttttt
    32221 aatttcctca tcagagaagt attctttcat cagaggcaag gtattgttga tggcacgagg
    32281 tgtaccgatt tcataatacc gccaattccc aacaatgctt tttttcacta ctgtagacat
    32341 gtttatgcat ccattccatg gaatccctaa ctgttcgaat aacggtttca tcctgataat
    32401 aacgagaaga aggattggtc acttgcttgg ccatctcctc caatttccga taagtggcag
    32461 ttagatgcgc agacgtttta taatttgaaa atttttccca caaataggtg cggctcgcct
    32521 gacttgaaat actggatagg ctatcagcca cctttccttc cagttcctgg tttaatttgg
    32581 ccatccgttc atttttagaa tcatagtatt gattcccagc gatgatacca ttccagtcat
    32641 ccaaacgggc tgtgtatgca tccttaacag aggctaaaat cttcaaagga atctttttca
    32701 cctccttgcc atctttactg acaatgacat tggttgtccc ttccttaaga ggttctaaaa
    32761 ttccattttt gactgaagca aaatcaggat tttctacctt ataagtatag tctacaagag
    32821 caaagacatg ttttttccca attggtaaat caatcttttc ctcgagctgt ttatctgttt
    32881 gagaatcctc agaaggctgg tctgctacct ctaccagctc aatatcctta aaaaaaatag
    32941 tctcagttcc cgtttcatag aataactcca gcttgatttt atcaacatct aaagtcgggc
    33001 tatagtctgc ttcaatggta ttccagtcct ttgttcctga cgtcgttgca aaattccaca
    33061 attgcttgtc cttaccactt tcctcaatga tacgaacctt agcaatcccg actttattat
    33121 ctgttttagt cttgaaatgc agtttatact ttttcttagc ttcaacaggg accatacggt
    33181 gaaccactgc ccttaatttc tcatggcttg agatagtgat agccccatcc ttagcctcaa
    33241 taactcgagt tgaggcatct gcagaactat tcttctggtc tacccaagct gaccacccct
    33301 gagctttgct ttctgtccac ggactgcttc cgtcctccgt ctgaccaaaa tcaccatctt
    33361 caactaaatt ttttgtatcc ctttactgat actgaacttc cttctggctt tgctgaatag
    33421 tattcgtagt cgtttcttcc gctccaactg tcatataatg gtttaataaa aatcctgata
    33481 aaacaagtga agacaaactc acaatgagct tctttgtttt tgtttgcatg tatacactcc
    33541 aataaacata ttgtaaaatc aataggaact aaatctcaaa ttagagattt atagcaacta
    33601 agtaaatcgg tttaattaaa ccacaccatt ttttaagctg tttgtaaacg atttctatta
    33661 tatcaagaac ctatttttca acaatatctt ccatccgact cgacgaaaaa agtaaaaact
    33721 gttacaatgt agaaaaagaa aagaggccct catgacttca ctatacgatt tttccgtttt
    33781 agaccaaaac aaccaatcaa ctccactaga gacctatcgt ggtaaggttc tcttggttgt
    33841 caacactgct actggatgtg gtttaacgcc ccagtaccaa ggacttcaag aactctatga
    33901 tcgctatcaa gaacaaggtt ttgagatttt agacttccct tgcaatcagt ttatgggaca
    33961 agcaccaggc agcgcagagg aaatcaacac cttctgtagc ctacattatc agaccagctt
    34021 cccacgtttt gccaagataa aggtcaacgg taaggaagca gatcctctct atgtttggtt
    34081 gaaagaacaa aaatctggcc cactgggaaa acgagtcgaa tggaatttcg ctaagtttct
    34141 tatcggtcgt gatggtcagg tatttgaacg cttctcttca aaaacagacc caaaacaaat
    34201 tgaagaggcc atacaaactc tactataatt tcacaatctc actatgatta ggtttccttt
    34261 agcctaatga atagtgagat tttttgatga gctttgactt aaatagaaaa acaccccatg
    34321 atatgaacca tgaagtgttg taaattctat gttgtagtgc ttatttcaca ttttcaatgt
    34381 gaccagtgat aacgaatacc ataccgaagc ttcatataca ctaaacaaat gactttctaa
    34441 ttatctcaat tagttttcat tagtaaatat catttccaac aaacgccctc tcaattcctt
    34501 atcctgatga tgcaagatat tcattaagtc atgagaattt ttggcattga tgaattgatt
    34561 taacaatcta tcttttaatt catatggaag agaagccgtc tttagtagtc taaaaacttc
    34621 atcatttaga gatggtgttt tattatcttt ccattcaaaa ttagctgtat cattcttatt
    34681 tggcaattca attatagaca cattcgttcc tttaaaatga attctatgtt ttctattgct
    34741 tggaacgata ctagaatctc cttgtaatgt tagctctacc atccccattt cccagtcgat
    34801 tgataatctt gttttatatc tttgaccatt ttgatcttca atcatttcaa aagaatgttg
    34861 cttgcctggg aatacatacc aatctacaac ttcaggtaaa tcaacaccca tatctatctc
    34921 agaaccaacc aagggaatga ttgcaccact ttttgcaaac acaggcgtag tcgagatgtc
    34981 cctataaaca cttaacttca caccacctgt gtattttttc tctgaaaaga agtcatacca
    35041 ttcaccttca gggaaccata catctacttt tgcagattgg aatgtcaaat ccatcttttc
    35101 tacaatggga gccaccatca gttctgttcc aaaaaagtat tggtttggaa cattatagct
    35161 ctcatcattc tctggataga aataatagat tggactgatt aatggggcac cttcctcatg
    35221 tgtctttaca ttcatggtat atagataagg aatcatctga tgtctcaaac gaaggtattt
    35281 cttcataatc ttagatgttg tttctgaaaa aaaccaaggt tctttactat taaaaggact
    35341 tctagaacta tgtaatcgag taatcggact aaaaacacca aactgtagcc atctagtttg
    35401 tagctcttcg tcataatccc ccaacatatg tccaccgata tcatgactcc accaactata
    35461 accgatatta gatgctgtcg ctgtaaaata gggttgaaat cttaaggaat tccaactaat
    35521 aatagtatcc cctgaaaaac caacagggta gcagtgacta ccaggacctg catatcttga
    35581 taaaatcaaa ccaccttctg catttttaca actatcctga tagtgataat ggtttaaaag
    35641 ccaaagtgga tctagcatac cttgtgtccc ttgttgccag tcaatccacc aaaaatctac
    35701 tccctgcttt tctagctcat aatgaacatc tttaaagtag gcttccctaa aagagggatt
    35761 aaaaaaatca aaaatagcag gttcttctag ttctacattt aaccccaatc gttttgcgat
    35821 ttgaggataa gcttcttcat aagcccgtat cccatcagca ggatggacat ttaaggagag
    35881 ttttaacttt ctatcatgaa gttgttgcaa taactgttct ggatttggta ttaagtttct
    35941 attccaacta tatcctgtcc agccacttcc aaaacgagct ggaatgtcag ttatatgcca
    36001 atccatatct aacacaccga tagataatgg aattttctct gtttcaaatc tgtctattaa
    36061 atccaagtat tcatccgacg tataaggcca atatctactc caccaattgc ctaaagcata
    36121 tcttggcaac aagggtgttg aaccagtcaa atggtaaaag tctctgattg ctcctctata
    36181 atcatgccca taagcaaaga aatacaggtc aatttgattt tctctctcaa tataaccaga
    36241 ttgttcatcc caaataaatc cttgagaatc atccaataag gctataccat ttcggctaat
    36301 aattccatct tctaacgaga ttgctccatc tgccttatcc agagtccgag ctgttccttt
    36361 taacgtttca atagattcac caaaatacca gcgactacca tatacggcaa aatttccttt
    36421 taattctata aataaatttt cggcgttaaa ttctccttta ttaaagtgca gatgaaaata
    36481 gtccgtcata atatctagta catttgatgt ctcgatataa tctaacgaaa cttggccaaa
    36541 atctctatta tagataagtt gtgtcgttct atcctcaaaa tttccagttt gagagtattc
    36601 taaccttact agcttgtctg ttaatacaga gattcgataa aactctccct taaaaatttt
    36661 caatttgttt tcctcctttt atggtagcat aaaaacagaa cgcaccattt ttgatgcgtt
    36721 tttcattatt ctgaatgcaa tgttctatct gttatatcta tgacaaataa tagtcaattg
    36781 aaaaaaatgt agtggacaaa atatctttta acaaaccaag agtttattaa agagttatca
    36841 cttttcaact tttctaagct tatgcagttg tgaaacaaac tacttttaaa ctattaacta
    36901 agataggatt gataaataat ttcaaactct tactagcaat catacgatat tcaagctcgc
    36961 gtgctttttt ccttcctgct tatttcttag aactgaagaa cccggatcgg tatataaatt
    37021 atccggatca acatagtcat aagactcata acagttgcgc ttcattaagt catccccaga
    37081 gcaagagctt catctcgtaa tttttcaaca tcactaaccg taggtcgcca tccttcaatc
    37141 atatttgtac ttaaagcata ccaaacactc ttaaaaacgg atcggttttc aaaagctatt
    37201 cccatgattg tcatcttttc tttatctata tctaaggaca tatgctacct cctttagata
    37261 cattatacca tgtttctctg tagcttttaa aaattttatt ttgtttgtca tatctaagtt
    37321 ttcagtacgc ttatcctatt ttataagcct caaacccaaa tataaaacgc attaaccatc
    37381 tgataatatg cgttttattg tggaaacatt tcccattttc tctatttcta atgacttact
    37441 tcaacttctg acttcatgga aaaaacaaca aaaatatgaa ctggcaaagt ttggtatcat
    37501 cagtaatcca gaacaattca tctttactta catagatacc aaaggcaata tcaataaacc
    37561 tttacattct gactatctca ataataagat gaaaactatc agaaaacgac acccagagct
    37621 tacacacgct acgccacaca aactacgtca taccggagca acgctcgcta aacaagcagg
    37681 aatgagctta gaagccattt ctgaagctct aatacatagc gacacaggta caacacagat
    37741 ttatgtcaat acttctaatg tagtccctat ggccgtcggt gaatttgcct tacagtctct
    37801 aaaacaataa ggtgaaaata aggtaaactt tgaggtgaac tttttcaaaa aacataaaaa
    37861 aagcacccat gaggtaaact cttgagtgct ttgaaacgtt gatataattg tattgattaa
    37921 cgttttgagg caactgacct tgtcaggttg cagccacatt tgtaagcgac taaagtcgca
    37981 acaactgtgt caattgcacc aatttagtaa gaaagtataa aaaaagaaca ccccgaaagg
    38041 tgctctgtat aagtatagta attctttcga attaacgttt actaaattgt gatgctttac
    38101 gagctttctt aagacctggt ttcttacgtt caactttacg tgagtcacgt gtaagaagtc
    38161 ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg aagaagggca cgagcgatac
    38221 cgtgacggat agctcctgat tgaccagcgt atccaccacc tacaacgtta acgaaaacgt
    38281 cgtatgaacc tacagttgaa gtaactgcga atggttggtt gatgacaaga cgaaggtcag
    38341 cgtgtgggat gtactcttca acatcttttt tgttaacagt gattttacca gttcctggaa
    38401 caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt acctgcatat tgtgcttgtg
    38461 acatacttta tttgttcctt tccttagata agtcctgaaa tgtcaagaac ttctggttgt
    38521 tgtgcagcat gagtgtgctc agctccaaca aatactttca acttcatacc ttgagcgcgt
    38581 ccaagtgtat tgtgtggaag cataccttta actgatttct caatcaaacg tactgcattt
    38641 ttagaacgaa gttcacctgc agagatttgt ttcaatccac ctgggtggtt tgagtgagtg
    38701 tagtagattt tatcagttgc ttttttacca gtcaatttaa ctttttcagc attgataaca
    38761 atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg gtttgttttt tccgcgaagt
    38821 acgctagcaa ctactgcaga aagacgtcca agtggtacat cagttgcgtc aactacgtac
    38881 catttacgtt caacttggcc tggtttagcc ataaatgttg ttttgttcat gatttctcct
    38941 atatatagtt cgatttttgt ttacggtgat gggtgttcct tcccatcgaa aagtatttgg
    39001 aaggttccgg ggcctttcaa atggggtaaa caataccgcc tactatcata ccaaatttca
    39061 cccctaaaag tcaatagata tgaaaaatat ttttcggtaa cttctcaaag taactgaaag
    39121 ttatataatc aagttaattt gggaatttac ctattaactt cggtagattt ttgggaattt
    39181 ttttccttct ttttccctgt agttaaaatc cttttcaaaa aatcaccttt tcttgatttt
    39241 taatcctatt tgctgtatga taagggaaaa gaaaggagac agagatatgg cttttaccaa
    39301 tacccacatg cggtctgcta gttttggcat tgttaccagc ttgcctgatg acatcattga
    39361 ctctttttgg tatattatcg accatttctt aaaaaatgtc tttgaattgg aagaagaact
    39421 tgagtttcaa ttgctcaata accaaggaaa aattaccttc catttttcaa gtcaacacct
    39481 ccctacagct attgattttg actttaacca tccttttgac cctctatatc cgccaagagt
    39541 actggtttta gacatggatg gtagagaaac tatcctcctc ccagaagaaa atgacctatt
    39601 ttaaaaactc tagtcttcag ttacaaatga ctgaaaacta gagttttttt attttttcaa
    39661 agcattatac aagttgcgga tcggttgctt taatgtcgga tggataaaat gagacgcaat
    39721 ttcctgtaag gactcaagga caaaaaggcg ttccgctatg taaggatgag gcaagataag
    39781 gtcatctgta taaaggatct ggtcctccac aaagagcaag tccaaatcaa tcaaacgagg
    39841 tccccaatgc acttctctca cccgtcccat ctctgactca atggctaaca aggtttctaa
    39901 caagactggt gctggtagcc aggtttctac ttcaatcacc tgattagcaa agctatcctg
    39961 ctccactcca ccccaaggct ccgtcgctaa gacactggac tctttgagaa tatggatgcc
    40021 acgagctcgc agtttgtcaa tggcttgctc caagtttgct tgtttatctc ccatattgct
    40081 tcctagggcg ataaaggctc gttgcttgcg gcgatgaatg gttaccgagc aagtatctag
    40141 tggcaaatgc actggtgccc aaggtttttt tagttccagc tttatttctt ggacaagagg
    40201 ataggtctca aaagtacgtt ccaccagttt ataggctacc gtttcaatca aatcttcact
    40261 cgtttcctga aaccaagtcg tccactgctg acacaattct ccgtaatgga cagaggctgt
    40321 taaatccaag tctgtagctg ccttggtcat atcataggat aggatggctg aaacgacaaa
    40381 tttctgcccc aattctttct cactaggaaa aagaccatga taggcaaaca tttccaaatc
    40441 cttaatctgc agttgatcca taatgattcc tttctagaaa aatccgcttg aaacggattc
    40501 tttttatagc cccattaaac gataagcttg gtcgcggagg tccttatctg tttcaaatag
    40561 accacgagct actgtcgtca aggttgcagt gcctggtttt ctaacaccac gcatactcat
    40621 acacatatgt tccgcctcaa tgacaacaaa ggctccttta gcacctagat agtccatcaa
    40681 ggcatcggcc acttcgatat tcaaacgttc ttgaatttgt ggttttttcg aataaacttc
    40741 aaccgtacgg gctagcttag acaagcctgc cacacgacca tctggaatgt aggcaatgtg
    40801 cgctctacca taaaatggca agaagtggtg ttcacacatg gtatggaaaa agatatcctt
    40861 ttctaccacc atattatcgt caataatttc aaaggatttt gacaaatgtt cctctgctgt
    40921 ttgaccaaga cctgaaaaaa tctcttgata catacgggct acacgagcag gtgtttcctg
    40981 caagccctcg cgattagcgt tctctcctac agcctcgata atcattttta cagctgcttc
    41041 aatcttttgt gtatccattc tcgttcttcc tctccatcag ataggccctc acttggctca
    41101 agaaatacaa ggaacctgtg acaatcctaa ctgtttgttt ctcttctttt ttatctgtca
    41161 aattctgctc tagaaaatca tgccaatctt ggtagctgag atttctagac ttagctgcct
    41221 ctttcagcac gctttcatcc gtcgcccgac tatccgcaaa atgtgttaga gtaagctcgg
    41281 tatctggcat agctcccagc aagtccaaca tatcccccaa ggctttggtt ttgatacaag
    41341 tgaagaggat ttccttatga taatccgcaa aacgttcttg caaggttacc aacaaggcct
    41401 tgatagcatg gggattatgg gctccatcca aaatcatcaa gggatctctt gacacgattt
    41461 ccaaacgccc tggccaactt gtttcttcca aggcttgacc aagaaagtca ttgcttgcta
    41521 gctctcgacc atcttcttga caaaaagtat caagtaaagc tatggccatc ccagcattct
    41581 ctatttggta caaaccaagc aggctagtct ggaagcgacc ttgtctgaca gcacttgtat
    41641 agtcaaagac ttcccctgtc accacacttt cttgatgacg aacctgataa tctgtcccgt
    41701 aggcaagtct cggcgcatct ttcccttccg caatgcggtc aatcacagcc aaggcttctg
    41761 gagcgatacg acctgtcacc aagggagttc cttgtttgat aatgcctgcc ttctgctctg
    41821 ctatggcctc caaggtgtca ccaagtaggg ccacatgatc cagtccaata gtggtgatgc
    41881 ctgtcaaaat gggctggcaa acattggtac tatccaaaag tccacccatg ccaacttcca
    41941 tgatggccac atctacttgc tctaaggcaa agtagtcata ggctatggct gtaattattt
    42001 caaactcagt tgtcccctgc aaattggtag ccgattcccc ctcaagcaaa gaccggtagt
    42061 ctgccatgag ggcttctagc ctagcctctg gaatggattc cccgttgatg ctaatctggt
    42121 ctgtgtaatg aatgagatag ggagagctaa acacgccaac tctcagccct agcttttcta
    42181 gcatcttttt caaaaaagca atggtcgaac ccttgccgtt agtccctccg atatggatga
    42241 ccttgagttt gagatgggga ttgccacgca aagctaacag ttccaccatt cgttccaagc
    42301 caaaatgcgg ttgatccgtc cggtagttag caatccactg attgttttca aattctttca
    42361 tcttatttat attgttttaa atctaaattt tccgcttcat cagccagacg aatagcggag
    42421 gcaatttcaa ctgccatcct gtgactagct acatcatgca cgcgcaccac ttccacaccc
    42481 tgtctcacag cgatactggt tacatgagcc gaagccgtat ctcgattgcg gaaaccaagt
    42541 tctgtctcag gattgacttc aaaaccattt tcttcaagaa tattgatgac aaaccgcttg
    42601 cgcgacactc cgagaaagat tggatagcct ttctgatgta gtttatccag atcccgtaaa
    42661 agaagcagat tttctttctt ggtcaaacca aagccaattc ctggatccaa caagatattt
    42721 tcttgtgcaa taccagcttc ctctgctctc gctaaggctc tgtcaaagaa agtctccatc
    42781 aagtcttcta ttggcaatgt ttcaaagtca gctaactctt tttctgtaaa agcttgacca
    42841 aaaccaaaat gaggaaagat gagcgagcta gggtgctgag gtcgtgctat gactggatta
    42901 aacataatga ctactttcgc tccagcctta gcaaccacat gggccatttt ttcatcaccc
    42961 atgagaccag tgatatcatt gactagattg gcaccagcag ccaaagcagc ctctgctacc
    43021 tgactcttcc aagtatcaat agagatgagg acattacttt ccttgcgaat agctttgatt
    43081 actggaacaa cacgctggat ttcctcttct atctcaacat agctgcttct tcccggccga
    43141 gtcgattctc cgccgatatc tagcatacta gccccttctg ctatcaattt acgagcctgc
    43201 tggagtgctt gctcaagagc aaaaaattga ccaccgtccg aaaaggagtc tggggttaca
    43261 ttgataattc cgcaaatagc tgtctttgca tgattggctt tacttgacat atcggtcact
    43321 ccctcaaggc ttttcaccat attatttctc tattttacca taaaaagaaa aagatggaca
    43381 caattgcatt catctttttc ccagtagaaa caagtaagca attgtcaaaa atcttaaaca
    43441 gagatcccta atgtccgact caaaatcacc acgagagcca acaaacagaa agcaacccca
    43501 ttcacaatca tgtgaagtaa gatagacatt tccaaacgtt gggtcttgta agccgtccaa
    43561 gatagaacga tcgacatacc tccataaatc aataaagaag gtaaattact tggttgatgc
    43621 aataaagcaa acacaaccgt accgactaca aatcccaagt tctcttttcc tcggaaaatc
    43681 tttttaggaa caatcccacg gcacaagatt tcctcacaaa ttggagcaag caaggccaac
    43741 aagaagaaac tggaaattaa ggaactattc tgaaccatat cgttaatctg agactggtta
    43801 gctgttgtcg tctcatttga cagttgcaac aagatagaac caagtatatt tgacccgaca
    43861 ataactaaat aactcaagcc caaacgtgcc aaatctttag ctctaaaaaa agaaaaatta
    43921 aaactagcta acttggtttt acgagctccc ataataaata gagccagaac cacaattgaa
    43981 aggccagtaa ctatcagccc tgactgtagc agggctactt cttttaaagt caaaatagag
    44041 gtaaccacta ggggaacctg atataaaagg acggcaagta aaaagaccaa aatccagcct
    44101 gcacgattca acaattcttt ccacatattt ttctctttca tcacctatct cctttgtatt
    44161 aaaaaaaggg ggaaatcccc ctgggtcatt ctattataag gccatgctga tgtagttaag
    44221 gataaacaag gcatccaaaa tccaaatcat ggcatgaaca tctttaactt gacctttgac
    44281 aagcttagtc aaagtgtaag tcaagaaacc aactgcaatc ccttgagtga tagagtagct
    44341 gaatcccata aagatagatg tgaagaaggc aggaactgct tcagacatat catcccaatg
    44401 gatatttttc aagctaccaa gcatcataat cccaacgata atcaagattg gagctgtagc
    44461 cgctgttggt acgatcgcta gaagtgggct aaagaagctt gaaatcgcaa aacagatagc
    44521 tacaaccaag gctgtcaaac cagtacgtcc acctgcaccg ataccagcag cagactcaac
    44581 ataagtcgtt acgtttgaag tacctgcaat ggcaccgact gtcgttccaa tcaaatcaga
    44641 gtaaagagcc ttatccaatt tggctgattg gtgattttca ccatttgtcg ctacgatacc
    44701 aactttttca cctgtaccga tcaaggtacc aattgtgtca aaaatatctg tcaatgagaa
    44761 ggcaagaatg gccatcagag tttcaggcaa gcgagctgta tctgaaacca aagctcccaa
    44821 accttctgaa ccaagagctg caccaaagat tgtcttcaaa tcttcaaaag ctgcaccaac
    44881 atggttatta gcaaaatcga tactagacaa atcaaccaaa ccaactgcaa tagcaagaac
    44941 agttgttgtc aagatagaga gaataattcc ccctttaatc cctttgatga caaagaagat
    45001 agtaatggca agtcctgcaa gagccactaa aacagctgga ttattaaagc tgaccaatcc
    45061 tggaactgct gaagagtttg ctgcaatcgt tgcttgagct ttgtcagccc cttctcctac
    45121 aacagtatag ttgcctggat caatcgtgaa tttcaaaagt ccagcattct taatccctac
    45181 ataggcaagg aagacaccga taccagctga aatagctgag cgaagagcat tgggaatcga
    45241 ttcaatgatc attttacgaa catttgtcaa ggtaataatc aatgaaataa tcccacagat
    45301 gaagaccata gctagggctt cttgccaaga ataaccaagc ccgaatacaa ctgtaaaggt
    45361 aaagaaggca ttgagtccca tacctggcgc ttgggcataa ggtaagttag cataaaaagc
    45421 catcatcaag gtacccgcta ctgcaccaat aatcgtcgct aggaagacgc cctgagcagg
    45481 cattcctgtt tgtgaaagta tttgtgggtt tacaaagaga atatagctca ttgcaaagaa
    45541 agttgttaaa ccagcgagaa cctctgtacg aacgtctgta ccgttctctt ttagtttaaa
    45601 taatttgtcc atcatcaatc tccttttaat ttttacgaac aataatagaa ttatatcatt
    45661 tatcattcac tttttcaatg tctttgtttg atttgtttaa gaaattaatc caatttcatt
    45721 ttttgtttgg aatctgcttt tctgcctgct ttctgttata atagaagaca tcttatctga
    45781 aaacacacta gaaaggtcca tatgacgaaa aaaattattg cagttgacct ggatggaacc
    45841 ctgctcaact cagacagtca aatttctgac tttaccaaaa aaaccatcaa aaaagttgct
    45901 gaaaaaggcc atcaggttat tattacgaca ggtcgccctt accgtatgtc aaaagatttt
    45961 taccgtgaac tgggcttaga cactcctatg attaacttca acggatccct tactcattta
    46021 ccagaccaag tttgggattt tgaaaagtgt ttgactgtag acaaaaaata tctgctagat
    46081 atggttcaac gttcagagga cattcaagcc gattttatcg ctggagaata tcgtaaaaaa
    46141 ttctacatta caaatcccaa tgaagaaatt gccaatccca aactatttgg tgtagaagct
    46201 ttccagcctg aagatcaatt ccagcctgaa ttggtgacca aggaccctaa ctgtatcctc
    46261 ttgcagacca gagccagtga caaatatgcc ttggcaaaag acatgaacgc cttctaccag
    46321 catcaacttt ctatcaatac ctggggaggt ccgctcaata tccttgaatg taccccaaaa
    46381 ggtgtcaaca aggcctttgc tttggactac ttgctcaaga taatgaatcg tgacaaaaaa
    46441 gatttgattg cctttggaga tgaacacaat gataccgaaa tgctcgcttt tgctgggaag
    46501 ggttatgcca tgaaaaatgc caatccagag ctactccctt atgcagatga gcaaatttcc
    46561 cttaccaacg accaagatgg ggttgccaaa accctacaag acttattctt ataacctata
    46621 ctgatactca atgagaatca aagagcaaac taggaagcta gccgtaggtt gctcaaagca
    46681 ctgctttgag gttgtagatg aagctgacgt ggtttgaaga gattttcgaa gagtatgacc
    46741 agcttgcaag ctggtctttg tgctcttttc acagtctcat caaccagtta atcgattgtt
    46801 ctactttttg tctccaaaac cttggaaaag gcttcctttt gtgatatact tcacatataa
    46861 atacaagaga gctcgtcaca ctcgactctg ttgacaaaaa atcaatccag tcccgttgtc
    46921 cctgttctcg gtcaatatca aggaggatag ctatgaaagc tgttgttgta aatccagaaa
    46981 gcactggtgt tgctattgaa gaaaaagtac tccgtccact tgaaactggg gaagcacttg
    47041 tagaagttga atactgtggc gtttgccaca ccgacctcca cgttgctcat ggtgactttg
    47101 gtcaagtccc aggacgtgtt cttgggcacg aaggtatcgg tatcgttaaa gagattgctc
    47161 cagatgtgaa aagccttaaa gtcggtgacc gcgtcagcgt tgcttggttc tttgaaggat
    47221 gtggcacttg cgaatactgt acaactggtc gcgaaaccct ttgccgtaca gtgaaaaatg
    47281 ctggctactc agtagacggt ggtatggctg aacaatgtat cgcaactgct gactatgctg
    47341 tcaaagttcc tgacggactt gatccagccc aagcttcttc tatcacatgt gctggagtaa
    47401 caacctataa agctatcaaa gaagcaaaag ttgaaccagg ccaatgggtt gttctttacg
    47461 gtgctggtgg acttggtaac ctcgctgttc aatacgctaa aaaagtattc aatgctcatg
    47521 ttatcgcagt cgatatcaac aatgacaaac ttacccttgc aaaagaagta ggcgctgaca
    47581 ttgtgattaa cggcctcgaa gttgaagatg tagctggact cattaaagaa aaaactgatg
    47641 gaggagctca ttcagctgtc gtaactgctg tgtctaaagt tgccttcaac caggctgttg
    47701 actccattcg tgctggtggt cgcgtcgtcg ctgttggtct tccttctgaa atgatggaac
    47761 tcagcatcgt taaaacagtc ctcgatggaa tccaagtcat cggttctctt gtcggaactc
    47821 gtaaagactt agaagaagcc ttccaatttg gtgcagaagg tctggtagtc ccagttgttc
    47881 aaaaacgtcc agtagaagat gctgttgcca ttttcgacga aatggaaaaa ggccaaatcc
    47941 aaggacgtat ggtactcgac ttcacccact aatttaatag aaacctattt taaaagttgg
    48001 aagcttcttc caactttttt atattaaatt ttaaataaga attcaagatt actcctcaaa
    48061 aactcaacat atcaacatac aaaaataaaa attttttaat tttttatgat aaatagttgc
    48121 tttttttatg aaaacggttt atacttaaac agtcttaaag ttttcttaaa tgaaaactaa
    48181 aacaaaaaag gaggaatgac aataatgagt atcggaatca ttattgcgag ccacggcgaa
    48241 tttgctgctg gtattcatca gtcaggatct atgatctttg gtgaacaaga aaaggttcaa
    48301 gttgtgacct ttatgccaaa tgaaggtcct gatgatctat acgctaagtt taataacgct
    48361 gttgctgcat ttgacgcaga agatgaggtt ctagttttgg ctgacctttg gagtggttct
    48421 ccatttaacc aagctagtcg cgtgatggga gaaaatcctg agcgtaagtt tgccatcatc
    48481 acaggactta acttaccgat gttgattcaa gcctacacag agcgcctcat ggacgctgct
    48541 gcaggtgtag aaaaagtcgc tgctaatatc attaaagaag ccaaagatgg catcaaagct
    48601 cttccagaag agctaaatcc agttgaagaa gttgcaagcg ctgcagctgc tccagttgcc
    48661 caaactgcta tcccagaagg aactgttatc ggagacggta aattgaaaat caatcttgcc
    48721 cgtcttgaca cacgtctact tcacggtcag gttgcaactg cttggactcc agattcaaaa
    48781 gcaaatcgta tcatcgttgc ttcagataac gtggctaaag acgaccttcg taaagaattg
    48841 attaaacaag cagctccagg taatgtcaag gctaacgtgg ttccaattca aaaactgatt
    48901 gagatttcaa aagacccacg ttttggagaa acacatgccc ttatcttgtt tgaaacacct
    48961 caagatgccc ttcgtgccat cgaaggcggc gtgccaatca agactcttaa cgttggttct
    49021 atggctcact caacaggtaa aacattggtc aataccgttt tgtctatgga caaagaagat
    49081 gttgctacat ttgaaaaaat gcgtgacttg ggtgttgaat ttgatgtccg taaagtacca
    49141 aatgattcta aaaaagattt gtttgacttg attaacaaag ccaatgtcaa ataagccatt
    49201 atttatgaaa ggattttaaa catgtctatt atttctatgg ttttagtaat cgttgtagcc
    49261 ttctttgcag gtcttgaagg catcctcgac cagttccaat ttcaccaacc acttgtagcc
    49321 tgtaccctta ttgggcttgt aacaggtcac ttggaagcag ggattatcct cggtggatcg
    49381 cttcaaatga ttgcccttgg ttggtcaaat atcggtgctg ctatcgctcc tgatgctgca
    49441 cttgcttctg tcgctgctgc cattatcatg gttcttggtg gtgactttac caagactggt
    49501 atcggtgttg cccaagcggt tgctatccct cttgccgtag ctggactttt cttgacaatg
    49561 attgttcgta caatttcagt tggtttggtt cataccgcag atgctgccgc taaaaaaggt
    49621 gacttcggcg ctgtggagcg tgcgcatttc attgcgctac ttttccaagg acttcgtatc
    49681 gcgcttcctg cagctcttct ccttatggta ccaactgaaa ctgtacaaag tatccttagt
    49741 gccatgccag actggctcaa agatggtatg gctatcggtg gtggtatggt cgttgccgtt
    49801 ggttacgcca tggttatcaa catgatggca actcgtgaag tatggccatt cttcgctctt
    49861 ggtttcgttc tcgctgctgt gtcagatatt actctaatcg gattcggtgc tatcggtgtt
    49921 gctatcgctc ttatctacct tcacctttct aaaactggtg gaaatggtgg cggaggagcc
    49981 gcaacttcta acgacccaat cggcgatatc ctagaagact actaagataa gaaaggactg
    50041 aaaacatcat gactgaaaaa cttcaattaa ctaaatcaga tcgtaaaaaa gtttggtggc
    50101 gttcaacctt cttacaaggg tcttggaact ttgaacggat gcaaaacttg ggctgggctt
    50161 atacactcat tccagctatc aaaaaactct atactaaaaa agaagatcaa atcgctgctc
    50221 ttgagcgtca ccttgagttc ttcaacactc atccatacgt agctgctcca gtcatggggg
    50281 ttactcttgc gcttgaagaa gaacgtgcta acggtgtgga aatcgatgac gctgctatcc
    50341 aaggggttaa aatcggtatg atgggacctc ttgctggtat cggtgaccca gtattctggt
    50401 ttacagtacg cccaatcctt ggatctctcg gtgcttcact tgcccttact ggcaatatct
    50461 tggggccact cctcttcttt gttgcatgga acttgattcg tatgtcattc ttgtggtatg
    50521 ttcaagagat tggatacaag gctggatcag aaatcactaa agatatgtct ggtggtatcc
    50581 ttcaagatat cactaaagga gcttctatcc ttgggatgtt cattcttgct gtccttgttc
    50641 aacgctgggt aaatattaaa tttgctttcg atgtttctaa agttcaacta gatgaaaagg
    50701 cttatatcca ttgggataaa ttgccagaag ggtctaaagg tatccaagaa gcattcgcac
    50761 aagtaggaca aggattgtct caaactcctg aaaaagttac tactttccaa caaaacttgg
    50821 atatgttgat tcctggatta tcaggactac tccttacttt actttgcatg tacttactta
    50881 agaaaaaagt atctccaatc actattatcc ttgccctctt cgcagtgggt attgtggcac
    50941 atgttcttca catcatgtaa tcaagcaact aaaaaggaac caggttctaa aatctgattc
    51001 cttttttcta tgcttttatt tagccaaggc tcccattgga tcccatggtg caagtacaat
    51061 tggttctgct ccataggcag cttgttcttc tgctgtcagc aattccttac gaacaacgat
    51121 ttggtatgtg tattcgtcca tccaagcgtc tgaggcaaca aagtaaccat ctgtaccgac
    51181 cttgtctccc catgagtttt caaccttcca cttggttgat ttaccatttt cgtccaagtc
    51241 aacacctgtc aagaccatgg cgtgggtcat caagctttcg ctatagtcca aacgtccagc
    51301 cttgtcttga gtaagtttaa tgtccatgct tgattcaaag tcataaacat ctgtcgcaag
    51361 gattccagcc ttacggttac tgagctggcc gacatcagaa ccaaaccaaa cagtctcacc
    51421 tgcttgcatt tgggcaatcg ccaattcttt caagcgctcc attggaacgt tgatgtaacg
    51481 aactgcacgg ctaccaacca cattccccaa catctcaact gtgtaagatt ttccgtaagg
    51541 tttatcagca gttggagcat tgataacaga aacgtagtct tctaaaggaa gattgacata
    51601 tttcttgtag aactcttgtg gtgtgattcc tttttcactt ttgtagttgt tatctttatc
    51661 gcgataagca aagtcaaact tgcgtggtgg aagtcctaat gacatagcaa gaaagttaaa
    51721 gatttcttgc aagaggtctt ctttcttagc ttgaacagtc acttgatctg caccagaaac
    51781 aagcaaatca cgcaagattt gagcatcttg acgaagcaat ttattaagga tcgcatttag
    51841 ctcacgactg ctgctagatg aaacagactc aggataaact gacttaggca cgacaccgta
    51901 tttttcaaag agggaaacga ccatatccca ttgaccacca tcttgttgag gtgtttggag
    51961 taagaagcta accttgcggc tagtcaattc ttggtctgaa gtcgcaatga cttgctccaa
    52021 gaaccagttt gatttctcat acttatccca gaagaaagtg tgggcttgtg acaactcaaa
    52081 gttctccaat ttgtattgcg agatgagttt gtggcggaag gtgttgagag ccgcaaacat
    52141 ccagcaacga ccagacgctt tctggttagt gaccttgtcc ttggttaaat ccaatgagaa
    52201 aacaggtgtg ttgtctacat ggctttggcg acgttccaga gctgcaaaaa ttccgttgtg
    52261 gctggcagca ttttcaatcg cttggtattt tacatttgct tcatagttgg caaatagttt
    52321 atcagtaaat gattcttgaa tcgcgttcat agattcctcc ttttattcta cagtctatta
    52381 taactctttt cacaaaggaa gcaactaaaa aacataaaag gtaaggacat tctccctcac
    52441 ctttttcgaa tttatactct tcgaaaatct cttcaaacca cgtcaacgtc gccttgccgt
    52501 actcaagtac agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtattaa
    52561 actaaattaa ataatattag cgcggagaat ttctaattct tccttggtca agcgacgcca
    52621 ttcccctcgt tccaggttct catctaatac taaagttccc atagtcaatc gttgcaagtc
    52681 caccacttcc ttgccacagt agcccaccat acgcttgatc tgatgaaact tcccttctgc
    52741 aatggtcaca cggatttggc tctgattctt ttctgtatct atggatacaa gctccagtat
    52801 agcgggttga caggtaaagt ctttgagagg aataccctca gcaaatgtct ccacatcttc
    52861 ttgggtcatg attcccttga cttgtgccag ataagtctta tccacatgac gcttgggcga
    52921 aagaagaaca tgagccagct gaccatcatt ggtcaagagc aaaagaccat gcgtgtcaat
    52981 atccaagcgt cctactggga aaacttcctt actccgcgcc aagtcatcca acaagtccag
    53041 aacggttctg tgcttgggat cctcagtcgc tgagataact cctttgggct tgttcatcat
    53101 gtagtagaca aactcttcat actccaacac ttgcccatca aagcgaatct catctatttt
    53161 ttcatcaatc tgcaatttag ctgatttttc ttttttacca tttacagtca cgcgcccagc
    53221 cttgagcaag tttttgacct cagtccgact tcccaccgca caggcaacta aaaatttatc
    53281 taatctcata gaactattat atcatatcaa aaggaggctg gtacaatgac caacctcctt
    53341 ttcgtttcat actcttcaaa aatctcttca aaccgcgtca acgtcgcctt gccgtatata
    53401 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgtttttag ctgacttcgt
    53461 cagttctatc tgcaacctca aagcagtgct ttgagcaacc tgcggctagt ttcctagttt
    53521 gctctttgat tttcattgag tatcagattt aggaaattaa cttcctcgtc tccaaaaaat
    53581 agctaaaaca atcatggctc ctaaaatcgc tgggataata gctgttcctg ataaaactgg
    53641 cccccaagtt ccaaagagca agtgacctag aaaggctccg atccaaccga gaaacatttt
    53701 tccaaaacat cccattcgct ctccacgatt ggtcatagca cctgctaaaa atcccactag
    53761 gagaccaacg aacatacttc ctaacatatt atctccttaa tttgcccaat tcccattacg
    53821 gaaaagaggt acccgcgttc catcctcacg aataccatcg atatccattt ggttagaacc
    53881 aatcataaag tctacgtgaa catctgaacg gttaagccct gcagcttcaa gctcctcttc
    53941 gctcatctcc gctccatcaa caacgctagt cgcataggct gcaccgatag ccaagtggtt
    54001 tgacgcattt tcatcgaaaa gggtgttaaa gaaggtaatg cctgactgag aaattggact
    54061 tggatctggt accaaggcac attcacccaa ggcacgcgca cccgcatttt caaagacaag
    54121 gtctttcata acctgatcac ccttctcagc agtgatatct acgatttgtc catccttaaa
    54181 ggtcacctta atgccttcaa tgatatttcc gttgtagcta agcggttttg tagaagtgac
    54241 ataaccatct gcacgacgga agtcaggcgc tgtgaagacc tcttctgtcg gcatatttgg
    54301 caagaattct tcgccctgtg cattgacagc accagctgat tcccaaacgt ggttctttgg
    54361 caaaccaagt gttaaatctg ttcctggcgc tgtgtagtga agggctgaaa attgctcctt
    54421 attaagcata tcggccttgc tcttgagaat ggctgcatgt tcctcccaag ccttaacagg
    54481 atctgcttcg tagacacgac aagttttgaa gatttgatcc caaaggaaat caactgcttc
    54541 ttcgtcgctc gcagcatttg ggaagacttt cttagcccac tcaagtccag cagcggctgc
    54601 tacagtccag ctaaccttgt tagattgagt tgcgattcgc attggcttca tggcaagtcc
    54661 catagcttta gcagaagctg aaagcttgtc agcgtccact ccgttcaagg cacctggatc
    54721 agatgaacga accccaagac ggctagcctt gttctccaaa agatagttca tctcagcaat
    54781 cttgtattct ggcacattgt ccaaacgctc catcggggca tggaggaatt tctcacggtt
    54841 aatcacatca tctgtccact gaacgatgac ctcatgcgca cccaaggcat aagcttcttt
    54901 cacgattaga tgtgccaatt cacgttgctc cacatcaata gagagagcca aagtgtgacc
    54961 aggttgcacg ttaattccgt tcgcaaccaa caatttcgca tatttttcta gattttcttt
    55021 aaaatttggt aaaaccattc tgttttctct tttctatttt tatttttctt tcaaagcaga
    55081 aaagattcct gctaaagcaa tagcacctga caagagtgct gtcgatagaa gaattgtacg
    55141 atcagcaagt tctaattgat attcaaatac cttcttagcc ggcttatctt ccgcaaatat
    55201 tcttagtttc atgagaaccc ccttaaaata gattaaaata aatcactgtg actgcctgtc
    55261 ctcagcaaat ttaaaatcaa ttccgacttg tctactttat aaaccaaaag ccaatctggc
    55321 tgggtatggc attcacgaac tccttgaaaa tgcttggatg ccgtcaatga atgatcacga
    55381 tatctggcag gatgttcttt ttcttgaacc agaaaattca aaacttcttc taataattct
    55441 gccttcaaac cacgcttcat agccaactta aaatcttttt taaactgttt atgataacga
    55501 atcttaagca cgtaagtcct ccatcaaatc tgagactgat tcaaaagact ggctcatatt
    55561 acgattttgg tctaaatccg ttaacgcttg gagcaacttc cgattttcgt ctagtctaac
    55621 atcaaaaggt aatccctgat attgaattgc ctgacgaagg aaaatattaa tagctgttgt
    55681 catatccatt cccagattac taaacacctg ttgggcctgc tccttaacct cactatccag
    55741 acggatgctt atactcatct ttgacatact ctcaccctct ttccatagac tattttaaca
    55801 aaaaagaaag ctaatgtaaa tctattggat atacgttagc ctcttttaat agattattaa
    55861 gcaatttttt aaaacaactc atcaaacaaa ctcaactggt tatcctctgg catatttcca
    55921 agaataccca tctcatccat cttttcaacc aaggttgatg agagtccacc acgcttgcgt
    55981 agttctgttt tagagaggaa ttctccctct tcacgcgccc gcaccagttg cttggcaacg
    56041 ttctctccca gaccatccat tgctacaaat ggtgggataa gggtatcccc gtcgatgagg
    56101 aactctgtcg cctgactacg gtagagatct aatttaccaa acttgaaacc tcgttcccac
    56161 atctcattga caatctcaag agttgtatag agatcgattt ccacattaga ggcttcattg
    56221 ttcttccgtt tttcagagat ttcttccatt ctgcgcttga tgacctccaa gcccgcaccc
    56281 atggtcttga tatcaaaagc cttagcacga atggagaagt aagcacagta gtaataaata
    56341 ggatggtgaa ccttgaagta agctacacgc aaggccatca taacgtaggc tgccgcatgg
    56401 gccttaggga acatgtactt aattttccca caggattcga tataccactc tggcacctta
    56461 ttggccttca tggcttcgat atagtcattt ctctcctctt ctgaaatctt tagccacaaa
    56521 cccttacgta cccgttccat aatggtaaag gccatcttag gttccagacc cgcatgcatg
    56581 aggtaaacca tgatgtcgtc ccgacaaccg ataacagtcg ataggtccgc tattccttgc
    56641 ttaatcagat cctgagcatt ccccaaccaa acgtcagtac cgtgggacag accagacagc
    56701 tgaagcaatt ccgcaaaggt tgtcggatgg gtttcgtcta ccattccacg tacgaaattt
    56761 gttccaaact ctggaatccc caacataccc gtaggcgttc caatttgttc aggtgttacc
    56821 cctagcacat cagtcccaga aaagagtgcc atcacgcctt cgtcatccat aggaatttca
    56881 ttagggtcaa taccagacaa atcctgaagt tttcgaatca tggtcggatc atcatgtccc
    56941 agtacatcga gtttgaggac gttctcatcg atatcgtgga agttaaagtg agtggtctgc
    57001 cattcagccg tgacatcatc tgctggatac tggacaggcg taaaatcgta gacatccatg
    57061 tagttcggaa taacaacgat tccccccggg tgttggcctg ttgtccgctt gacacccgcc
    57121 gctccttgag cgaggcgttc tacttctgca tcacgataaa acttgccata atctcgctcg
    57181 taacccttga caaatccata ggcagtcttg gcagctaccg taccaaccgt tcccgcacgg
    57241 aaggcatatt cttcaccaaa gatatcacgc acatccaagt gggcgctagg ctgatcttct
    57301 cccgagaagt tcaagtcaat atcaggaacc ttatccccat caaagccaag gaaggtctca
    57361 aacggaatat cctgtccgtt tttactgagt ttgtgaccac agtttggaca gtccttatgg
    57421 ggcatatcaa atcctgaacc gtacgaacca tctgtgataa actcactgta ctgacactga
    57481 ccacagacat agtgaggaga gagaggattg acctccgtaa tcccaatcat ggtcgcaacg
    57541 aaactagatc cgacagaccc acgagaacca accaaataac cccgttcatt agaacgttgc
    57601 accagcatct gcgatgccag ataaatcaca gcaaatccat tccccagtat ggatgttaat
    57661 tctttttcaa tccgcaaatc aacaatatct ggcagcggat ttccataaat ctcaaaagct
    57721 ttcttatagg tcaactcagc aactgtttct tcagccttgt cgatgaaagg cgtatacaag
    57781 tcacccttaa cgacttcaac gggttcaaat atttctgcca aggcattagt gttttcaata
    57841 accagtttac gagccagttc ctctcccaaa aaggcaaatt catccaacat ctcattagtc
    57901 gttcgaaaat gagcctttgg aagtggtgct ggttgggcat gttcaccatg accgatagtt
    57961 cgattaatca tcgcaccctg tcccaaacta cggacaataa tttcacgata aatctcttct
    58021 tccggttcga tatagtgaac atttcccgta gccagaacag gcttgccaag gcgatctcca
    58081 acctctatca aactcttgat aatggtctgg agttcctcca tatccttgac ctgctctttg
    58141 gcaatcaagg gcgcatagat agccggtggc atgacctcga taaagtcata atacttggcc
    58201 acctcaaccg ccccatccac accttgagaa acgaccacgt caaaaacttc accctctgaa
    58261 caggctgaac ctaaaatcaa gccctctcga tgggcatcta gaaccgttct cggaatccgt
    58321 ggcactcctt caaaatactt ggtattagac aaggaaacca gcttaaagat attttttaga
    58381 cctacctgat tcttgacata gatggtcgca tgcttgatcc gagctttttt gtaagaatct
    58441 ggactgatta gatcaatgtt gagtctagct aaatcggtca caccatgttt ttctgctacc
    58501 tctttgataa agatgaaaag cagacgacca gtcgcttccg catcgtagtt ggccatgtgg
    58561 tgatgttcca aggccacacc aaaacgcttg gtcaaaggcc ccaaaccatg gcgtttatac
    58621 tcaggataga ggtttctagc aaactccagc gtatcaataa ctggctgact aatctttgga
    58681 agatcatgac gctcataatt agcattcata aagccaacgt caaaggtagc attgtgggca
    58741 actaggaccg tatccttgca aaattcttgg aattcttgca aaacttgttc tagtggtttg
    58801 gcatttttga catgatcatc tgtaattcca gttaactctg tagtaaaagc tgacaaggga
    58861 tgcccaggat tgataaattc atcaaattca gcaataacat tccccttgta catcttagag
    58921 gccgcaacct gaatcaagtc attatagata gctgaaagtc ccgtcgtttc cacgtcaaag
    58981 accacgtagg ttgcttctga caagtccatc tccacttcgt tatagacgat agggacacgg
    59041 tcctccacga tattggcttc cattccatag atcagctgga ttcccgcttt cttagccgcc
    59101 ttatagccat gtggaaagga ctggacattc ccatggtccg tgatagcaac cgccttgtgt
    59161 ccccacttag cagctgttgc aacaatctct tcgacctctg gcaaagcatc catagtcgac
    59221 atgttagtat gagcatgaaa ctcaacccga cgctcacctt ctggcatcaa atccttccgc
    59281 tcatagtgaa caacttcctg cagatcctgt acgttcatag tcaaatcgcg tgtgaagtta
    59341 ttcatctcca cattccctcg aactcggagc caagaattct tcttgatgag gtcaaacttc
    59401 tgggcctctt cctcgttttt aacccacttt tgcatagaaa aacttgaagt atagtccgtc
    59461 attttaaagt tgattaaaac acgacctgtt ctagtcactt tttgctccac atcaaaaaca
    59521 accccttcaa ataccagacg attttcctct gtcgtcactt cgatcatagg agtaatctcc
    59581 gccttatcca gcttgggttt agctgcagct tttttcgctt gaaaatcaaa gactggtttc
    59641 tcttccgctg gaggaggtgc catctgctcc agttgttcca tagcacggag cgcttcctca
    59701 ttggcagctt gaacaatctg ctcattttca gcatgaaagg cctcttcctg ctcttgggtc
    59761 aggacatcat tcttctcgac ttgacagtta aaagttggaa aaccaaactt ttcaagttgt
    59821 ttggctaaat taggaagatg attcttctta aaatgttcct tatcaatcgc ctcagatcct
    59881 tcaataaata gctgattacc ctcagcacga acttgcaaat tttgataaag ggacttaaaa
    59941 ccttgactag cacatggacc ttcagagaaa gcctccctat agtaggactg caagagctga
    60001 tttgaaaatt cttgagaccg agccttaatt tcaaaaacag ctttattgcc tgtcttagaa
    60061 aattcttcgc tcaaaccttt ctttaattct aaaaagattt caatcggtaa aatattagaa
    60121 aatacgaaat gaaactccca taccttacta attttatgaa ccacaactcg ctcaatattg
    60181 gcctgtgcta aagcaggagc ctgtctcatt tcagcaggca tccccaattg attcatcaaa
    60241 atttcaaaac tatttgacat tcattttcct cacattattc ttctactatt ttaccatatt
    60301 tagaggtatt ttctaaagac aaaaggaagc cactaagtga cttccttcta gagtgaggac
    60361 ggattagtct tcacctttat ttttcttaat aatttcttct tgtactgact taggtacatc
    60421 ttcgtagtgg tcaaatacca tcatgaatgt accacgtcct tgagatgcag aacgaagaac
    60481 tgttgcgtaa ccgaacattt cagcaagtgg aacgtaagca cgaacgattt ggctgttacc
    60541 gtgtgcttcc ataccatcta cacgtccacg acgagcagtt acgtgaccca taacatcacc
    60601 aaggttttct tctggaacag tgattgttac aagcatcatt ggttcaagga tagctggttg
    60661 tgctgattta gcagcttctt taagggaaag tgaagccgca atcttgaagg cagtttcaga
    60721 tgagtcgaca tcgtgatatg aaccatcata aagcttagct ttaacgtcaa ccattgggta
    60781 acctgcaaga acaccgttag ccatagattc taccaaacct ttttcaaccg ctgggataaa
    60841 ttcacgagga accacaccac cgacgattgc gttttcgaat tcgaatcctt taccttcttc
    60901 gtttggagta aattcaatcc acacatcacc gaattgacct ttaccaccag actgacgttt
    60961 gaagaatcca cgtgcttgag tagaagcgcg gaatgtttca cggtaagata cttgaggcgc
    61021 acctacgttc gcttcaactt tgaactcacg acgcatacga tcaacaagga cgtcaaggtg
    61081 aagttcaccc atacctgaga taactgtttc accagtttca acgtttgttt caacgcggaa
    61141 tgttggatct tcttcagcca atttttgaag ggcgataccc atcttgtctt ggtcagcttt
    61201 agattttggc tcaaccatca attggataac tggttctgga acgttgattg actcaaggat
    61261 gattttagat ttttcatctg tcaatgagtc accagttgta gtatctttca aaccaacggc
    61321 agcagcgata tcacctgagt aaacagtgtc gatttcttga cggctgttag cgtgcatttg
    61381 aaggatacgt ccgatacgtt cacgtttacc tttagaagta ttcaatacgt atgaacctga
    61441 ttgaagaaca cctgagtaaa cacggaagaa tgtcaaacga cctacgaatg ggtcagtcat
    61501 gatcttgaag gcaagagctg caaatggctc ttcgtcagat gctggacgag tttcttcagc
    61561 gtctgtatct gggttaatac ctttgattgc tgggatgtca agtgggcttg gaaggtagtc
    61621 gataaccgca tcaagcatca attgaacacc tttgtttttg aaggctgaac cacacaatac
    61681 tggaaagaat tcaacgttga tagtcgcttt acggatacca gctttcaatt cttcgttagt
    61741 gatttcttca ccttcgaggt atttcatcat caattcttcg tcagtttcag caactgcttc
    61801 aatcaatttt tcacggtatt cttgagcttg gtcaaggtat tcagctggga tgtcttcttc
    61861 aaggatatcc gtaccaaggt cgttagtata gatttcagct ttcatcttga tcaagtcaat
    61921 gataccacgg aagtcatctt cagaaccgat tggcaattgg attgggtgtg catttgcttg
    61981 aagacgatcg tgaagtgtgc ttacagagta aaggaagtca gcaccgattt tgtccatttt
    62041 gttggcaaat acgatacgtg gaactccgta ctcagttgct tgacgccaaa ctgtttcagt
    62101 ttgaggttca acacctgatt gtgagtcaag aacggtaacc gcaccatcca atacacgaag
    62161 agaacgttgt acttcgattg tgaagtccac gtgtcctggt gtgtcgatga tgtttacgcg
    62221 gtggttgttc cattgagctg ttgtcgcagc agatgtgatc gtgataccac gttcttgctc
    62281 ttgctccatc cagtccattt gtgacgcacc ttcgtgagtt tcaccgattt tgtggatttt
    62341 accagtgtag taaagaatac gctcagtagt tgttgtttta ccggcatcga cgtgagccat
    62401 gataccgata ttacgagttt tttcaagtga aaattcgcgt gccatgaggt ttgtttctcc
    62461 tatttatttt tgatttctat tctattataa cacgatttta ataaaaacgg ataggcagga
    62521 cctacccgtt ctcaatgttt tcatgctatt gttggtttca acttactaga tggtaagctg
    62581 agttatagct aatactaatc gatttagcta atttgaaccc gggctaaagt tagttagccg
    62641 atgtgagctg gaacgggatg ctgcgtgaaa aagataaaac tccttgtatt cgttgaatac
    62701 tgcgtcagtt tcctattttc accttgcatc cttaccgtgc ctagcatcat gatttagttg
    62761 agctcaagct aaaagtctgg agaaaaagat gaatctcatt ggttgcaacc gcaacctgct
    62821 tcgattccct attttctctg ggactttctt aacgctttcg catcctatct taccaacgga
    62881 agtgtgcgaa tgcacggtta gcttcagcca tacggtgagt atcttcacgt ttcttaacag
    62941 ctgcaccagt gttgttagca gcatccaaga tttcttttgc aagacggtct tgcattgtgt
    63001 gttcaccacg aagacgagcg attgttacca accaacgaag tccaagtgtt gtacgacgtt
    63061 ctggacgaac ttcaactggg acttggtagt tagaaccacc aacacgacgt gcacgtactt
    63121 caagtacagg catgatgttt tccatagctg tttcaaatac ttcaagtgca tcgttgccag
    63181 tagcttcttt gatttgctca aaagcaccgt aaacgattga agcagcagta ccacgtttac
    63241 catcaagcat aacgcggttg ataagacgag taactagttg tgaattgtat agcggatctg
    63301 gcaatacgtc acgttttgga gctctatttt tacgactcat ttctctttat cccctttcct
    63361 tatgcttttg gacgtttagt accgtattta gaacggcctt gtttacgatc gttaacacct
    63421 gcagtatcaa gtgcaccacg gacgatatgg taacgtaccc ctggaaggtc ttttacacgt
    63481 ccaccgcgaa gaagcaccac gctgtgctct tgcaagttgt gtccgatacc tgggatgtag
    63541 gcagtaactt cgataaggtt gctcaaacgt acacgagcga atttacgaag ggctgagtta
    63601 ggttttttag gtgtcattgt tccaacacga gttgcaacac cacgtttttg tggtgaagaa
    63661 acgtttgttt gaactttttt atgactattg taaccaacgt tcaaagctgg tgatttagat
    63721 ttttctactt ttgatttacg cggtttgcga accaattggt taattgtagg catctacatt
    63781 ctcctgtgtt tttttatttt tggtgatgat acacttggtg acagatatca tctgtgtgta
    63841 cttttgcaac atttgtcagc acgtccctgt acactcttga gagaccaaaa gtaaaaagta
    63901 ccgtctatta ttgtaacaaa attttccctt gcttgtcaag atatttttct tttttattgg
    63961 taatgttaga gatcaatttc tgaataaaaa tagctgggaa cacatcatct tcctaataat
    64021 acggcttggc ttatgtgaca tttttatctc cgtcatttat actgatatat aaacccaaat
    64081 cattcatacc tctctcaact agatgtaact tacaaaaccc ctgacctcat gagccacttt
    64141 cttcctcctc atgaggtcag ttttactttc tgctgttcca gtatcgtttt tcctcgctag
    64201 atttcctcaa aagggcagac tcctcccttg gtgcgtcaca cgattttttc atctcgactg
    64261 ttctttaatg catcattaac gacgcttttc ttccaggtgg ttcataagga acaggaagat
    64321 tcaggttgac ttttctaatc ctagaataaa gtgctgaaaa caattcggaa taggcataga
    64381 gactagacaa tttgaggagc tgcttgcgtc ctgttcgaac acattttcct accacgtgaa
    64441 gaaaaagatg gcggaagcgt ttgattgtta aagtttggaa gtcgcctcca gctagatgtt
    64501 tgagaaaaag atagagattg taggcgatac agctcatcat catacgaact tcgtttttga
    64561 ttaaggttga actatccgtt ttatcgccaa aaaatccctc cttcatctcc ttgatgaaat
    64621 tctcggcttg accacgtcca cgataaagct gaaactggtc ttggcttgtt ccactcgtca
    64681 tatttgcaac gagagaaata acatcgtaga acaagtttcc ttcttttcgt tcagagaact
    64741 ggcagacacg acgcttgtgc gaccaagatc ctgcttgata gagagtttct gagtaggcgg
    64801 agtggggcaa gatggttaag tcctcatcct gtgggcaagg gagggaaagg tctccaagac
    64861 ggctcagaac agtatttttc ttgagtttta tgaggtagta ttgccctgtt ttttcaatta
    64921 aatcgtataa ttttggggtc gcaaagccac tatccattcg aaagagaagt tgattaaacc
    64981 gttctaaaac aggtgtgata aagctgtctg cctcttcaga acaataacga ttaccaggac
    65041 gaagctgggc attgaaacaa taacctgtct tcccctcgaa agcataaaga ggatgatagc
    65101 catgagcacg atagtgggcg ttataagcaa caccttcttg cttgccataa gttgtgaaat
    65161 gggtagaatc gatatctaca atgagttggt ttagctggtg aaactgtaaa aagaattcga
    65221 ccaattcaag gttgaggcat cgcaaactat ggactgtttc ctcgtcagtt ctggaaagaa
    65281 aacgggataa ggttggctgt gaagcaagct gccctccttc caacaatttt ggaaagtagg
    65341 catcagctga caattcttta caagcatagt ccgttccata gcctgttaac agttgaaaga
    65401 ggaactggac aaggatatct gaatccgaat aacgacagta gcggcgttgg tcattcgtta
    65461 ctaaatactt agaaatccgc tcttttagtt tcaactggga aaaaagttcc tgaaaaaaga
    65521 taagaccacc atactgggtt aaatgacctc catcgaaaga tagttgataa aaagacttgt
    65581 tttggaagtg atgatttggt aaactgttca tgtgagtttc ctttcttttt gtgttttttt
    65641 ctacacttat accataaagg ggaaactctt ttttgtctag taaaaaacac ccattgggtg
    65701 aaaaaagaaa ccatccagga tctaagctaa ggcaaggatt ctggatggtt tttagatttg
    65761 gggtgaataa ttggggttaa aatagtacag aaaacttctc aaaagtaaga atttttttca
    65821 caaatcaaag aaaacgcttg catattgttt tactacatgc tatactgata tagaaattta
    65881 ttgattggag aatcattatg agaaaaacac catctcacac tgagaaaaaa atggtctaca
    65941 gcatccgttc cctcaaaaat ggaactggtt ctgtccttat cggcgcaagc cttgtcttgc
    66001 ttgccatggc tacaccaact atctcatccg acgaaagtac accaaccact aacgaaccca
    66061 acaacagaaa tacaaccacc cttgcccaac ctcttactga tacagcagct ggctctggta
    66121 agaacgaaag tgatatttct tcacctagaa atgcaaacgc ttccctagag aaaacagaag
    66181 aaaaacctgc aacagagcca actacttcta ctagtccagt aacaactgaa actaaggcag
    66241 aagagcccat cgaagataac tacttccgta tccatgtcaa aaaacttcct gaagaaaaca
    66301 aggatgctca aggactatgg acttgggacg atgttgaaaa accatctgaa aactggccaa
    66361 acggagcttt gtccttcaag gatgccaaga aagatgacta cggctattac ctagatgtca
    66421 aattaaaggg agaacaagcc aagaaaatta gcttcctcat caacaataca gctggaaaaa
    66481 atctaaccgg cgataaatct gtagaaaaac tagttccaaa aatgaacgag gcttggttag
    66541 accaagatta caaggttttc tcttacgagc cacagcctgc aggaactgtt cgcgtcaact
    66601 actaccgcac agatggcaac tatgacaaga aatctctctg gtactgggga gatgtgaaaa
    66661 atccaagtag cgctcaatgg cctgacggaa cagactttac ggctacaggc aaatatggcc
    66721 gctatatcga cattcctctt aatgaagccg caagagaatt tggattttta ttactagatg
    66781 agagcaaaca aggagacgac gtgaaaatcc gtaaagaaaa ttataagttc acagatttga
    66841 aaaatcatag ccaaattttc ctaaaagacg atgatgaatc gatttacaca aatccatact
    66901 atgtccatga tatccgtatg acaggagccc aacacgtagg cacttctagc attgaaagta
    66961 gcttttcaac acttgtcggt gctaaaaaag aagatatcct caaacactcc aacatcacta
    67021 atcacctagg aaacaaggta actattaccg atgttgcaat cgatgaagct ggtaagaaag
    67081 tgacctacag cggagatttc tctgacacaa aacatcctta tactgttagc tacaattccg
    67141 accaattcac taccaaaaca agctggcgcc tgaaagatga gacatacagc tatgatggca
    67201 aactgggagc tgacctaaaa gaagaaggaa aacaagttga tttgaccctt tggtcaccaa
    67261 gtgctgataa ggtttctgtt gttgtctacg acaagaatga ccctgacaaa gtagttggaa
    67321 ctgtcgctct cgaaaaaggg gaaagaggaa cttggaaaca aactctagac agcacaaaca
    67381 aactcggaat cacagatttc actggctact attatcaata ccaaatcgag cgtcaaggta
    67441 aaactgttct tgcactcgat ccttacgcta aatctcttgc tgcttggaat agcgacgatg
    67501 ccaagattga cgatgcccat aaagtggcta aagccgcctt tgtagatcca gctaaactcg
    67561 gacctcaaga cttgacttat ggtaagattc acaatttcaa gactcgtgaa gacgccgtta
    67621 tctacgaagc tcatgtgcgt gatttcactt cagatcctgc cattgcaaaa gacttgacca
    67681 aaccatttgg gacttttgaa gcctttatcg aaaaactaga ctacctcaaa gacttgggtg
    67741 taacccacat ccagctcctt ccagtcttgt cttactactt tgtcaatgaa ttgaaaaacc
    67801 atgaacgctt gtctgactat gcttcaagca acagcaacta caactgggga tatgaccctc
    67861 aaaactactt ctcattgact ggtatgtact caagcgatcc taagaatcca gaaaaacgaa
    67921 tcgcagaatt taaaaacctc atcaacgaaa tccacaaacg tggtatggga gctatcctag
    67981 atgtcgttta taaccacaca gccaaagtcg atatctttga agacctagag ccaaactact
    68041 accactttat ggatgccgat ggcacacctc gaactagctt tggtggtgga cgcttgggga
    68101 caacccacca tatgaccaaa cggctcctag ttgactctat caaataccta gtggatacct
    68161 acaaagtgga tggcttccgc ttcgatatga tgggagacca tgacgccact tctatcgaag
    68221 aagcttacaa ggctgcacgc gccctcaatc caaacctcat catgcttggt gaaggttgga
    68281 gaacctatgc cggtgatgaa aacatgccta ctaaagctgc tgaccaagat tggatgaaac
    68341 ataccgatac tgtcgctgtc ttttcagatg acatccgtaa caacctcaaa tctggttatc
    68401 caaacgaagg tcaacctgcc tttatcacag gtggcaagcg tgatgtcaac accatcttta
    68461 aaaatctcat tgctcaacca actaactttg aagctgacag ccctggagat gtcatccaat
    68521 acatcgcagc ccatgataac ttgaccctct ttgacatcat tgcccagtct atcaaaaaag
    68581 acccaagcaa ggctgagaac tatgctgaag tccaccgtcg tttacgactt ggaaatctca
    68641 tggtcttgac agctcaagga actccattta tccactccgg tcaggaatat ggacgtacta
    68701 aacaattccg tgacccagcc tacaagactc cagtagcaga ggataaggtt ccaaacaaat
    68761 ctcacttgtt gcgtgataag gacggcaacc catttgacta tccttacttc atccatgatt
    68821 cttacgattc tagcgatgca gtcaacaagt ttgactggac taaggctaca gatggtaaag
    68881 cttatcctga aaatgtcaag agccgtgact atatgaaagg tttgattgcc cttcgtcaat
    68941 ctacagatgc cttccgactt aagagtcttc aagatatcaa agaccgtgtc cacctcatca
    69001 ctgtcccagg ccaaaatggt gtggaaaaag aggatgtagt gattggctac caaatcactg
    69061 ctccaaacgg cgatatctac gcagtctttg tcaatgcgga tgaaaaagct cgcgaattta
    69121 atttgggaac tgcctttgca catctaagaa atgcggaagt tttggcagat gaaaaccaag
    69181 caggaccagt cggaattgcc aacccgaaag gacttgaatg gactgaaaaa ggcttgaaat
    69241 tgaatgccct tacagctact gttcttcgag tctctcaaaa cggaactagc catgagtcaa
    69301 ctgcagaaga gaaaccagac tcaacccctt ccaagcctga acatcaagat ccagctccag
    69361 aagctagacc tgattctact aaaccagatg ccaaagtagc tgatgcggaa aataaaccta
    69421 gccaagctac agctgattca caagctgaac aaccagcaca agaagcacaa gcatcatctg
    69481 taaaagaagc ggttcgaaac gaatcggtag aaaactctag caaggaaaat atacctgcaa
    69541 ccccagataa acaagctgaa cttccaaata caggaatcaa aaacgaaaac aaactcctat
    69601 ttgcaggaat cagcctcctt gcgctccttg gtctcggttt cttactaaaa aataaaaaag
    69661 agaactaaac tagccctcct atagaaaaat cccccaagca ttatagctcg ggggattaat
    69721 ttttgtacaa tatttgttgt cctaataaac ttgattagga ttttttatta agcctctttc
    69781 atagcaaaat aagctcgtac tttgggtgca acttgtgttc cgaagagttc aatagctctc
    69841 agaacctggt catgaggcat agaaccaagc ggtagatgaa gcatgaagcg gtccaatcct
    69901 aaatcctcta tcatgcgaat caattttttg gccacctgat ctggattgcc aacaaacatg
    69961 gcgccatttg gccctacctg ctccaaatat tgctcataac gcaattcctg ccagtgcgga
    70021 cggtctttgg aaatagcatc caccacttgc ttagtcggat ggaaataatc tttcaccgcc
    70081 tgctcaccat cttccgcaat ccacccccaa gaatgggctc ccactttcaa gtctttgtca
    70141 gcatggcccg cttcgcttcc aatctcacga taagcctgaa tcaacttttt aaaataacgt
    70201 ggattaccac caataatagc atatacaatc ggtagaccag cctgagcaat cttcactgtt
    70261 gattcgacat gaccacctgt agctatccac aagggcaatt tgtcctaaac tggacgagga
    70321 taaacttctt taccagcaat cgtttgagtc aatcgacctt gccagtctaa cttggtcttt
    70381 tcattgacta actgaagcaa gtctaatttc tcatcaaaaa gagagtcgta gtctttcaag
    70441 tcataaccaa acagagggaa agattccgtg aaagagcccc ttccagccat aatctccgat
    70501 cgtccatttg acaaagcatc gatagtggca tactgttgga acaaacgaat cagagccatg
    70561 cttgacagaa tgctgactgc actggtcaaa cggattttct tgatattgac tgccccagcg
    70621 gccaggacaa tctctgggac tgatactgca aaatccgccc gatggtgctc gccaatccca
    70681 tatacgtcca aaccaacctt gtcagccagc tcaatctctg ccaccaactg gcgaatgcgt
    70741 tcagcatgac tgtaagtttg tccagtccct tcaagctccg ttatttcccc aaatgttgaa
    70801 attcccaatt ctaccattgt gattctcctt gtctatctct gtccttcaat ttgaaaaatt
    70861 attctaacac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gcgctcaaag
    70921 cactgttttg aggttgcaga taagactgac ggagtcagct caaagcactg ctttgaggtg
    70981 gtagatagaa ctgatgaagt cagctcaaaa tactgttttg aggttgcaga tggatgctaa
    71041 cctgatttga agagattttc gaaaaagatt aaatatactc tacaatttgc tcaatcaatt
    71101 ctgggtcgtc taaacctgta acttgtataa caacatcttt gactgattgt ttagccaaca
    71161 attcacctaa tcgaatactt tcttcatcat ttacatcgcg atagtcaaag gcatagccaa
    71221 ctgttttaag taggttttta tatgacaaac tgagttcttt caattcacgt atcggccgga
    71281 tgaatcgttc attatagcct aattttcgga ttggagtacg agctacgcga ctaacctcgt
    71341 ccactatgaa aggattttca aaccgttcta taatgacttt gtgataattc tccaattctt
    71401 ttttatcaaa gttccatttg gtaatcaaga gactccgaat ttcagctaat acagattcaa
    71461 tccgagattt gatattagga ttttgaagag cttccaaaat tgtcttggca ccataatgcg
    71521 caccaatgta agctgaagtt gcatgtccag aattgactga aaaaagtttt cgctcaataa
    71581 agggttctaa atcttcttca taatgcacat cttttagacg taaatctgga tttttaagac
    71641 gcttggtttc cacgacccat tcattaaagg gttcgaccac aacaaaaagg gaatcttcgt
    71701 gactttgtgc tggaacaatc ctgtctactg cagcatttgg aaaacctatg tagttatcag
    71761 caaatgtcaa accttccgga cttaaatatt tcttgacttc ttgataaaga aattgagacc
    71821 cgccaatcat attttcacag gccataacat ccaatgcctg tgtatttcct gcaactcggc
    71881 gagcttcgat tcctttggct agaagttcgg cgataaaagg gagtatatta ggtccgattg
    71941 cagtagtaat aatatccgtc ttttgaatcg cttcaatgac ttgctcagga tgttctttgc
    72001 tattaatgcc agccacatta gttacttcta tacgagactg tcctttctgt gcaatttcaa
    72061 tttcatactt gcccttttca tttagagcat gaattatctg attattgaca tccacaaaat
    72121 caatatggaa accactttta aatagaattt cacctataaa accacgaccg atattaccgg
    72181 caccaaaatg aacagaatgt ttcattcaat ttctcctttt cctatttgag ggacatatat
    72241 actagatgac aaatgacgaa attcaattat tcaacagcat caaataagcg caatacttcc
    72301 tcttttgact gagcatctgc tagtttaaga acattatcta catctgcaca gaagatagaa
    72361 attttctgaa taatttctaa gtgttcatta ccaataccag caataccaaa aagaaccgtt
    72421 gccacttgag ggttagatac attcccaaaa tcaacccctc tagggacttg aacgactgta
    72481 ataccagact tgaggacatc cttttttgct gcatctgttc catgcggtat ggcgataaag
    72541 ttacccatgt aaacagatag ctctttatct cgctcaatca tggcttcaat atagtcttca
    72601 ttaacatatc caccctcata aagaacttgc ccacaataac aaatagcttc ctccttgtta
    72661 gaaaattgtt tattaagctt aatcaaatgt ttttcaagtt tcatattagt tctccaattt
    72721 cttaattttt tcgttaaaaa tagtatttag catctgataa ataatggatt gatttcccgt
    72781 cttgtaaatc tctgtataaa gatgattttc aataatcgac tgactaatag ctgtcattaa
    72841 atctctcgct tcctcgctag cttctttaga cattagcatt agcagacacc ttttgacctc
    72901 ttcttcctct cgtttcattg acaatgcgga gataggtagt ttgagttcaa acatagtaaa
    72961 actatttgtt gttactttgc tagactgact atgtaaaagc accagaccag tattaggaat
    73021 agccatagga ctattctgga agtgagataa caattttctt gttaggtaat ctctgtcact
    73081 cacattcttc tgatattgga tgatttgttc taccgtgtgc tcaaatgatt gattattctc
    73141 caattgaacc aactcgaatt gactcaaaag ctgactacta gatattaaat aatcttgcaa
    73201 gtcataactt ttctctggag cgatagcatc acgcgcgaca attgtacgat gtgcctgtac
    73261 atactgaagt cgttcctgta attcaagcag ttctttgacg gttggaaaac tagaaattac
    73321 atcgatttcc tgattagtca gcggcttggt agataaaata taatcatact gactgagatc
    73381 aatactgtgg taatctacta gagactgaat atctatcaac tctacaaaag gagcaacact
    73441 cttaatttta ctgactaata aatctctagt gacccgacgt tcatccgtta aaagcaaaac
    73501 acggactgga taaatctctg gactacggcc taagctagag ataaaatgta gggcaatcat
    73561 gccatactca tactctgtat gaagatattt cggaaaaata tcattcacta aaagactgat
    73621 gactgtataa agaaatttat tcctttcaac taaaatctgg acagattctg gcaaattttc
    73681 accctgaaaa aggataggga cgcctaaact gagccgaata tgatggaaaa gaaaattgaa
    73741 taaaaccttg tccttaaaaa agtcaatctt ggtatacatg gaaaccgtat caatcagatt
    73801 tgaaatattg tagaaaaatt caccatcaaa tttctccgta aagagcggat tgtcctgacg
    73861 tttaatgatt aattcatcta agatgctcgc aaaatagata atttcctgaa tactataaaa
    73921 ttgtgcagtc tgcttagagt aagcttgaaa aattttttga gaaatttcca aagcctgctt
    73981 actagtatta ggtgaatttt caatgttttg ctcctgacct ataagagata acaagatcgc
    74041 aaaaaacatc ttcatcctag catccatatc tggaaaacct gacagttgct tattaacaat
    74101 ctgactggcc agcctagttc tatctgcttc taaaatatca aagctcccaa aattaccggt
    74161 tgaaaaatct gctactgaga tacagtttgt cagtaaaata gccaaaaatc ttctcttacc
    74221 aactgaatca ccagaaatac gataaccttt ttgtcgttca attttcagat caaagtctaa
    74281 aagacgctta tcaatatctg aaatatcctg aataatagtt acattactga ctttcatgca
    74341 ctcttgcaat gcttcattgg tgacaaaacc actctcagtc agaaggcgat aggtaatcaa
    74401 ctcttgtctt tcttggggac tatactcaac taacacttca agttctgtcg gcaaatcatc
    74461 caactctcca gtcaaaatat agtatttccc atgcttcgtt atttcgattc catattgctc
    74521 catgctatct gtcaaatctg ataaagttcg ataaattgtt ctagatgaaa cctgtaagat
    74581 ttcagtcatg tcttgcattg aaagcttccc tacatgtagg aaagccttca ataattgttc
    74641 ttctcgtttg gttaatagca ttcgtaattt agaaacctct agttctattt gtacattcta
    74701 acagccattt tgtcatattc tggtgttgtt actaaactat ccacaataag aaattgagaa
    74761 ttcggtgctg tttgctgcac ttctgcctgt aaagaaatag ttgttacaat cattatgttt
    74821 ttagaattaa attcacctaa ttctgaaatt ttggcagtag aaactggaat acgaatattc
    74881 ttgtttctaa agatagcccg aatcgtttca cagcccatag ttgcagatcc ctgtgcttta
    74941 ccataagcaa ctactacagc atcaatatgg ttaaagtcaa tttcctgact atctactgat
    75001 gctgaagttg atatatctcc ttcaatttct gctattggag aagctcctgt taatgaagct
    75061 acaatttcat cataacgagg ggacgctaag aaattatcaa cagaaacatg aatagcactt
    75121 ggactcttgt ctttagctct tggtgtcagt tcttcctgag taacaattaa tgtttttggt
    75181 gtatcaagca aatttgagat tgcctgatta gatactggaa tctctagacc tgctttttta
    75241 accttatctc gaagaatact agctcccata gcagagcttc ccataccagc atcgcaggcg
    75301 aaaatgattt tttccactga gtctgtcgaa acaactgcat caacagaagt tgatactaac
    75361 tgacctttag actgagcctt agctgcttgg gtagccgcct gagcagcttc gagcgaatcc
    75421 tcagttgact tgtctgcatg aagaataagg gctgctacaa ggaaagaaac aactgctgcc
    75481 actaaaacac ctagaagaac atttagatgg ggccaaacgc cttttggcgc cgtagccata
    75541 atcgcaataa tagaacctgg tgaagctgga gatttaagac cagcgtctaa gagttgaaaa
    75601 gtaaaagttc cagagatacc tcctgccata gcagctaaaa atagagtagg cttcatcata
    75661 acataaggaa agtaaatttc atgaatccct ccgaagaaat gaataagcat tgccccccaa
    75721 gaagaagatt tagcagaacc tttaccgaat acagcataag ctaatagaat tcccaggcct
    75781 ggtccaggat tagcttccaa taggaagaga attgacttac cagcttgagc tacctgttct
    75841 actcccagag gagtaaaaat gccatgattg agggcattat tgaggaaaag gactttagcc
    75901 ggttcgatga taatattagc tataggaagg aggcgagcat taacaatagc ctcaacacca
    75961 ttcccaacag ctccagtaag agtcgatacg actggaccga ttgcgtagaa agccaaaagc
    76021 aataatgcaa aaccaacgag accagctgag aaattattaa ctaacatttc aaatccggga
    76081 cgaatttttt cctggaactt ttcatcaaat ttcttgatag tccatcctcc cagtgagccc
    76141 attaccatag ctccgataaa cataggaaca ctagaacctg tgattgcacc aacagtagca
    76201 atagctccta caacggcacc acgttgacca tggatcatat atccacctgt gtaaccaatc
    76261 aggattggca ataaatacgt taacatagga ccaacaacag tagctaactg ttcatttggc
    76321 agatagccat cagcgataaa gagggcagtc aacactcccc aagcaataaa tgctccaata
    76381 ttgggcataa ccatatttga aagcgatgtc cctagttttt gaactctgac tttcaatgat
    76441 actttttctt ccattaggat catcctcctt ttcttaaaac tagtatatac aaagttaaaa
    76501 acctttaaaa ctaaagtttt gtcacagatt ttgtgccaaa actttacttt tgacgaggct
    76561 gggcaaaaag gcttaaaaat gataaaacgc atcatatcag gtgtacaaaa ccttaatatg
    76621 atgcgtttta tcatggaaag atttactgaa ttttctcttc aaattgagtt tttgcccagc
    76681 ttcctctttt tatagtagtt tgaaataaga tacgaacaaa tcaattggaa aattcaaatt
    76741 aatttctaga aatattttag tattcctgtg tactgttcta aattcaatct gctataatta
    76801 ttgaaaagta aacccttatc atcatttgta acataaaaaa taggctgtaa aaccttatag
    76861 gataaaccta tggctttacg cccgtatatt catagattct attctaccgt tactgacttg
    76921 gcaaggttac gtggtttgtc cacatcgagg ccacggtgga gggttgcaaa gtaagcgacc
    76981 aattgtgttg gtacgaccat tgaaattggt gagaggtaag ggtgtacagt cgtaaggacg
    77041 atagcgtctg tctctttagc aacattttct tctgcgatag tgaggacttt tgcaccacgg
    77101 gctgccacct cttggatatt tccacgagtg tggttggcaa ggactggatc tgacaagaga
    77161 gtcaaaacag gtgttccttc ttcaatcaag gcaatagttc cgtgcttaag ttctcctgcc
    77221 gcaaagcctt cacactggat gtaagaaatc tctttaagtt tgagacttgc ttccatggct
    77281 acgtagtaat cttgaccacg tccgatgtaa aaggcgttac gagttgtttc aagtagctca
    77341 cgaaccttga cttcaatggt ttctttctct gaaagagttg attcgataga ctgagctacg
    77401 attgacaact catgaactaa atcaaaggct tgcgctttgg cattgccatt tgcttctccg
    77461 actgcttttg caaggaaggc aagggctgca atttgcgctg tataggcctt ggttgatgcc
    77521 acggcaattt caggacctgc atgaaggagc atggtatggt tggcttcacg agaaagagtt
    77581 gaacctggga cgtttgtcac tgtcaagctt gggattccca tttcattagc cttgaccaaa
    77641 acctgacggc tatctgctgt ttcaccagac tggctgataa agatgaagag tggtttcttg
    77701 ctgagaagtg gcataccgta accccactca gatgaaattc caagttcaac tggtgtatct
    77761 gtcaattctt ccagcatctt cttagaagca aatcctgcgt ggtaagatgt cccagctgca
    77821 aggatgtaga tgcggtctgc gtcttgaaca gcctgaatga tagcttggtc tacgactact
    77881 tgaccaacct catctgtgta ggcttggatc aacttacgca tcactgttgg ttgctcgtca
    77941 atttccttga gcatgtagta agggtaagtt cccttaccga tatctgacaa gtcaagttcc
    78001 gcagtatagc tagcacgttc acgactgtta ctatcatagt cttgaacttc cacgctatca
    78061 gccttgacga ttaccaactc ttggtcatga atttccatgt attggttggt ttcacgaatc
    78121 atagccatag catctgagca gaccatattg tagccttccc caagaccaat caaaagtgga
    78181 gatttgtttt tcgctacata gatgacatct ggattttcag agtcaatcaa ggcaaaggca
    78241 tatgaaccac ggataatatg aagagctttt ttaaaggctt caagaactga gagcccttct
    78301 tcttccgcaa attttccaat caaatgaacg gctatttcag tatctgtctg ccccttgaag
    78361 tggtgacctg caaggtattc ttccttgatt tcaagatagt tctcaatcac cccattatgc
    78421 accaagacaa aacgttctgt ctcagagcgg tgtgggtgag cattgtcctc agttggtttt
    78481 ccgtgagtag cccaacgagt atgtccgata ccagttgttc cctcaacacc agctgtcttg
    78541 gcagacaatt ctgcaatacg accaaccgcc ttcaccaaat ggttatcagc accatctagg
    78601 acaaaaattc ccgcagaatc atagccacgg tattcaagct tttcaagccc ttgaatcaaa
    78661 atatcagttg catttgtgtt tccaacaaca ccaacaattc cacacatagt atatacgaca
    78721 caggcaagct gtgctttctc cttaaaattg gtatagtcta attcatcttt tatagaatca
    78781 gcaaaaacag tatatacttg tttctttcac ttgtcaagag taaaaattgg tatagttcaa
    78841 attaagctcc tgtaagcata aaaactctga ccgattggga taatcagtca gagtcctttt
    78901 taaaatccat tattatcgct taattctttg aaccagtggc ctgatttctt cagacgacgt
    78961 tcttgcgttt ccaagtctaa ttcgaccaaa ccatagcgat ttttatagct gttgagccat
    79021 gaccagcagt caataaaggt ccaaatcaag tagcccttac agttggcacc atcttcaatg
    79081 gcacggtgaa gttcacgaag atgacctttt acaaagtcaa tacggtaatc atcttgaatc
    79141 attccatctt gacggaattt ttcttcccct tcaacaccca taccattctc agtcaacatc
    79201 cactcaatat tgccataatt ttccttgata ttttgggcga tgtcataaat cccttgctca
    79261 taaatctccc aaccacgatg agaattgatt ttacgtccag gcatcacata aggctcgtaa
    79321 aaatgttctg gtaagagtgg actctctgga tgcttagcaa atcgaggagc cataacacgc
    79381 aaaggttgat agtagttcac accaaggaag tccaccgtat tatcacgaat gagttccaac
    79441 tcttcctctg tagcatcagg taaaagaccg tgttcatgca agatttctac caactcctgt
    79501 ggataagtcc ccaagacaga tggatctaag aaagattggg cctgaaaaag ggccgcaata
    79561 cgagctgcct tgacatcagc aggatgctgg ctacgtggat aagccggtgt caagttgagg
    79621 acaatcccaa tcttggaatc aggcaaaagt tcatggcaag ccttaacagc ccgactgctg
    79681 gccaattgtg tatgataggc taccttaaca gctgcctctg catccacctt atgtggataa
    79741 tgggcatcat aaaaataacc aaattctaca ggaacgatgg gctcgttaaa ggtaatccat
    79801 tgatccacta aatctccata agtctcaaaa caaaaacgag catagtcttc ataggctaag
    79861 actgttgcct tattttccca accatcacca tcctcttgaa gggcaaaagg taaatcaaaa
    79921 tgatagagat tgactaacag acgaattcct ttagccttaa tagcctcaaa gaccttacga
    79981 taaaaatcca caccttgagg gttgactttt ccacagcctt gtggaaaaat ccgtgaccac
    80041 tgaatagaag tccgaaaggc tgtgtgacca gtctctaaca aaagctcaat atcccgctcc
    80101 caattttcat aaaaagtcga tgtcttatct gaaccaatcc cattatagta acgatttggc
    80161 tccacttgga accagtaatc ccagagattg tctcccttac cgtcaccagc tacacgtcct
    80221 tctgtctgcg gtccagaagt agaggagccc cagacaaaat cctttggaaa tcttagcata
    80281 catttacctc tttatctact catttctccc attatacaga aaaaacaagg taaaaactag
    80341 ttacattttt tccttgtttt tcttctgatt atagttttta tttcttgctt aggatttcaa
    80401 gcgtttcaag cacgttatct gcatgaacct caatggtgtc accagtcgcc ttaatcttaa
    80461 cttctacgat gccatcagct gctttcttcc caacagtgat acggattggt aacccaatca
    80521 aatcgctatc actaaacttc actccgacac gttcgttacg gtcatctgtc aagacttcat
    80581 aaccagctcc catcaagctt gcttcaagtt tttctgtcaa ggcttgcgct tcttcatcct
    80641 tgacattgac agtaatcaaa tgcacatcaa atggtgccaa ttctttaggg aaattgattc
    80701 cccaagcgta acggtattca ccttttggcg ttttgttaac aaagaggcga gcgtgttgct
    80761 ccatcactgc tgaaagaaga cggctgacac cgataccgta acatcccatg atgattggca
    80821 cagcacgacc attttcatcc aagacatctg ctcccatgct tgctgaatag cgagttccga
    80881 gtttgaaaat atgaccgatc tcaataccac gcgcaaagtt aaggacacct tgtccatctg
    80941 gggaaatttc accctcacga acttcacgga tatccacata ttctgcagta aaatcacggc
    81001 ctgggttcac acccgtcaag tggtagccat cttcgttagc accgacaact gcattgcgaa
    81061 catcttgcac cttacgatct gcaataattt taatattctc tggcaaacca actggtccaa
    81121 gtgaaccaaa tcctgcttga acaacattcg ccacttcttc ttcgctagca acgtcaaaga
    81181 aatctgctcc caagtggttt ttcaacttga cttcgttgag ttggtcattt ccaactagaa
    81241 gggctgcaac aagctcacca tctgcaatgt agaagagggt tttaatcgtt tgttcttctg
    81301 gaacattgag gaaagctgca acttcatcaa ttgatttaac atctggcgtt gcaacgcgag
    81361 taacttcttc ttcagcgaca acacggttgc ttggtttgta ctcgtttgtt gccatttcta
    81421 agttagctgc atagctagac tcacttgagt aagcaatggt atcttcacca gagactatcc
    81481 atttgagcaa ttctgccttg atttcttctt gcacttctgc aggaatttcg tcaaatgagg
    81541 caactgactt gtccaagaca acccagcggt caaggtctgt acgagcagat gtaatggcca
    81601 taaattcttg gctatcctta ccacccatgg ctccaccgtc accaataata gccttgaagt
    81661 ctaaaccact acgagtgaaa atacgctcat aggctgcttt gtactcatca taaacactat
    81721 ccaaactatc atagttagcg tggaaactat aagcatcctt catgataaac tcacgtgtac
    81781 gaagaagtcc attacgtggg cgtttttcat cacgatactt gggctgaatt tgataaaggt
    81841 tgagtggcaa ttgcttgtaa gatttaacag aatcacggac aatagctgta aaggtttctt
    81901 cgtgagttgg acctaagata aagtctgatt tttcacggtt ttttagtttg taaaggtctt
    81961 caccataggt ttcgtaacga cctgattcac gccacaattc tgcactaaga agggctggag
    82021 ccagcatctc aacagcacca atcttttcga attcttggcg catgatgttt ttagcttttt
    82081 caatcacacg attggcaagt ggtagataag aataaacacc tgctgaaact tggcgaacat
    82141 aaccagcacg caacataaga gcatggctga taacttgagc atcgcttggc atttcgcgaa
    82201 gcgttgggat aggcatttta ctttgtttca taatattcct cgattatcta aaaaagagtc
    82261 gcataatgtc attccaagtc acagcaatca tcaagacaac catgatgacc actccggcca
    82321 aggtgacata ggtttcaatt tcttgtttca atggtttgcg gcggatggct tctaggatat
    82381 tgagcacaat cttaccacca tccaaggctg gaatcggaat aagattaaaa atcccaatat
    82441 tgatggaaat cattgccaag aagtacaaga tattttcaat tccattttta gcagcatcac
    82501 tacttgcctt aaagatagca acaggtccac ccaacttgtt caaatctggt tggaaaatca
    82561 gatttttcag agctgagaga attcggagag ctgagtcagc agcagttgta aaaccaccta
    82621 caaacatgga tagaaaatct gacttaaccc ccggttgaac acctagaagg taacgacctt
    82681 gactatcttc gggtgtaaca gtgacttgtt tgtcactccc cttttcagaa atagtcacat
    82741 ccaaagtcgg tgccgtctta tctttggttt ctgtttccac agcttggatc aagctttccc
    82801 agttgctaac ctcatgtgag ccaatcttgg taatttgtgc cgtttctggt actcctacct
    82861 tggccaaggc accttggggc atgatatgga actgattggt atcaacatct ctgacaccac
    82921 cctgcataaa gattaaaacc caaaaaacaa cgacacctaa gataaaattg ttcataggac
    82981 ctgcaaaatt ggtaatcagt ttgccccaga tagtcgcatt ttgatattga acatctaaag
    83041 gtgcaatccg aacctcagta ccatctgctt ccacaaccgt tgcatcgtga tccactgcaa
    83101 atgttttttc ttcttccaga accaatcctt tgataaagag cttgtcttca aaatcaaact
    83161 gggtcacctg catagggagg gctgtttgat ccaatttttt acctgagaga ttgatgcgtt
    83221 taaccttacc atcatcagca agtgtcaaac taacaggcgt tcctgtcttg atttcagttg
    83281 tatcatcacc ccaaccggcc atgcggacat agccacccag aggcaagatt cgaatggtat
    83341 aggccgttcc atccttgcca atgtgagcaa aaattttagg tcccataccg atggcaaatt
    83401 cacgtactaa aatccctgat ttcttggcaa agtagaagtg cccgaactcg tgcaccacta
    83461 caataatccc gaaaaccaga ataaaggtta aaattccgag catagcgttt cctccgtctt
    83521 ttgattaaaa gagtccaaat aagtgcatga ttggaaatac aagcaacata ctatcgaaac
    83581 gatccaaaac accaccatgt ccagggataa atttcccaga atccttaaca ccaaaatgac
    83641 gtttgatcga actttctagt aaatcaccaa attgtccagc aatgctaaag aaaatagcaa
    83701 agactgacat cttgtaaatt ccatatggaa gagcaactgt actgtcaact atcataaaga
    83761 taatggttac taaaattgct cctaaaatac cacccaaggc accctcaagg gttttattag
    83821 gcgataccct tggtgctaac tttcgtttcc catagttcat cccaacaaga taggcaccac
    83881 tgtctgtcgc ccagacgata cacaaggcta agagagcctt gtccaaacct gcaacacgag
    83941 catctagtaa agcattaaat ccaaagccca cgtagaagct catagcaaga gggaaaaccg
    84001 catcctcaat cgtataagac ttgctaaaaa cggtcgttcc taacatgatt gaaatcaaaa
    84061 cactataggc aaccacattc ccatcaactg gcaaaaaagt caggtaattc tccaagggaa
    84121 tggtcaatgc aaaggttgca aagagggtca agaggccctc catcgtcatg gtctctagac
    84181 ctctcatctt caaaagttca tgcatggcta gcatggctat gattccgatt gctatctgaa
    84241 gcaagaggcc cccaatcatt aaaattggta ggaaaatagc cagggcaatc cctgcaaaca
    84301 aggttctttt ctgtaaatcc tgggtcatat ttcctcctaa actcctccaa atcggcgatg
    84361 acgacgatta taggcaagaa tagcttcctg caaggccact tcgtcaaaat caggccataa
    84421 ggtgtccgta aaataaagct cactataggc tccctgccat ggaaggaaat tgctcaaacg
    84481 taattctcca ctagtacgga taatcaagtc tgggtctcgt aagtccttag gcaaatgctg
    84541 ggtaaagaga tagttgccaa tcaattcctc tgtgatgtca cctgggttga ttttggcatc
    84601 taaaacatcc tgggaaatca acttaagcgc ctgtgtaatc tcagcacgtc caccatagtt
    84661 aagagcaaaa ttaagaatca atcctgtgtt gttcttagtc aattcctcag ccttggttaa
    84721 agcttcaaag gtttgcttag gcaggcggtc tgtctcccca atcatttgaa tcttaacatt
    84781 attcgcatgt agttccggaa cataattatc ataaaactct actggcaagt tcatgataaa
    84841 cttgacttcc tgatctggac gggtccagtt ttccgtagaa aaagcataga ccgtaataac
    84901 cttgacgccc agtttgttgg ctgccttggt cacggtttgc aatgcttcca tgcccgcctt
    84961 atgtccaaaa actcgcggtt gcatacgttt tttagcccaa cggccattgc catccatgat
    85021 gatgccgata tgagcaggaa cctgtgtcgg aacctctact tccacagcct tatctttctt
    85081 aaaa
//
LOCUS       DAVDHZ010000005        84038 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000005 DAVDHZ010000000
VERSION     DAVDHZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.005"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(86..1402)
                     /locus_tag="VUR46_000398"
     CDS             complement(86..1402)
                     /locus_tag="VUR46_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET5455893.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            1596..2822
                     /locus_tag="VUR46_000399"
     CDS             1596..2822
                     /locus_tag="VUR46_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET5455894.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            3021..4595
                     /locus_tag="VUR46_000400"
     CDS             3021..4595
                     /locus_tag="VUR46_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5455895.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFVDE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYCKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            4859..5647
                     /gene="codY"
                     /locus_tag="VUR46_000401"
     CDS             4859..5647
                     /gene="codY"
                     /locus_tag="VUR46_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET5455896.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDNYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            5647..6222
                     /locus_tag="VUR46_000402"
     CDS             5647..6222
                     /locus_tag="VUR46_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET5455897.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTGGRNLYGDLGIFYQEHDSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFSLGHFKNTLGAKLVDENLNELSE"
     gene            6304..6389
                     /locus_tag="VUR46_000403"
     tRNA            6304..6389
                     /locus_tag="VUR46_000403"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6338..6340,aa:Leu,seq:aag)
     gene            6672..7802
                     /gene="ugpC"
                     /locus_tag="VUR46_000404"
     CDS             6672..7802
                     /gene="ugpC"
                     /locus_tag="VUR46_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET5455898.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            8303..9061
                     /locus_tag="VUR46_000405"
     CDS             8303..9061
                     /locus_tag="VUR46_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5455899.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDAWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            9148..9660
                     /locus_tag="VUR46_000406"
     CDS             9148..9660
                     /locus_tag="VUR46_000406"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET5455900.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            9842..10786
                     /locus_tag="VUR46_000407"
     CDS             9842..10786
                     /locus_tag="VUR46_000407"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET5455901.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQNTLKEGHLLFRGFDDSYVSPHSRHTEISKEEILNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDCDAGLAPHIPENYFKDDDVNQTPCLC
                     WSSSAALFFSNWVNYAVYQETPFDWRKIEDDASAYGYL"
     gene            10795..11472
                     /locus_tag="VUR46_000408"
     CDS             10795..11472
                     /locus_tag="VUR46_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET5455902.1"
                     /translation="MTYLDAFKSGNLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLLGVAHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKANWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            11570..12328
                     /locus_tag="VUR46_000409"
     CDS             11570..12328
                     /locus_tag="VUR46_000409"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET5455903.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAAAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            12366..13856
                     /gene="lytC"
                     /locus_tag="VUR46_000410"
     CDS             12366..13856
                     /gene="lytC"
                     /locus_tag="VUR46_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET5455904.1"
                     /translation="MSVPFFIGEERLKTKIVCIGLASLCLLGARVSGIAADETSGSTV
                     SEKSSLSTGTSSTSSNEQRNSVSAHWDGDYYVKADGSKAQSEWIFDNYYKAWFYINSD
                     GRYAQNEWHGNYYLKSGGYMAQNEWLYDNNYKSWFYLKSDGAYAHQEWQLIGNKWYYF
                     KEWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQKVGGKW
                     YYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLNVGWVH
                     RDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLGYSGTE
                     DKELAHNIKELNRLGIPYGVYLYTYAENETDAENDANQTIELLKKYKMNLSYPIYYDV
                     ENWEYGNKTKRAPSDTGTWVKIINKYMATMKQAGYQNVYVYSYRSLLQTRLKHPDILK
                     HVNWVAAYTNALEWENPHYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            14355..14873
                     /locus_tag="VUR46_000411"
     CDS             14355..14873
                     /locus_tag="VUR46_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET5455905.1"
                     /translation="MVELKKEAAKDVATLTKAAPVTLAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMRGRGFMVWHPKMDEYMDALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLDIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            15003..15509
                     /locus_tag="VUR46_000412"
     CDS             15003..15509
                     /locus_tag="VUR46_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET5455906.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPQRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTQIHARVEGDTYFPEEFDLSLFETVSSKSYTKDEKNLYDFTI
                     QYRKRKEV"
     gene            15509..15679
                     /locus_tag="VUR46_000413"
     CDS             15509..15679
                     /locus_tag="VUR46_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455907.1"
                     /translation="MERSIFGFFTAMLCLVCLLAGAQAFRKKRYGLSVLLLLNAFTNL
                     VNSIHAFYMTLF"
     gene            15716..16948
                     /gene="clpX"
                     /locus_tag="VUR46_000414"
     CDS             15716..16948
                     /gene="clpX"
                     /locus_tag="VUR46_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET5455908.1"
                     /translation="MPTTRNNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKEAVDGTDKPILETA"
     gene            16957..17544
                     /locus_tag="VUR46_000415"
     CDS             16957..17544
                     /locus_tag="VUR46_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET5455909.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGRMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            17555..17935
                     /locus_tag="VUR46_000416"
     CDS             17555..17935
                     /locus_tag="VUR46_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET5455910.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ETIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            17987..18877
                     /gene="rapZ"
                     /locus_tag="VUR46_000417"
     CDS             17987..18877
                     /gene="rapZ"
                     /locus_tag="VUR46_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET5455911.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKNLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NYPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            18874..19851
                     /locus_tag="VUR46_000418"
     CDS             18874..19851
                     /locus_tag="VUR46_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET5455912.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQIILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            19848..20759
                     /gene="whiA"
                     /locus_tag="VUR46_000419"
     CDS             19848..20759
                     /gene="whiA"
                     /locus_tag="VUR46_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET5455913.1"
                     /translation="MSFTVAIKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(20847..21974)
                     /locus_tag="VUR46_000420"
     CDS             complement(20847..21974)
                     /locus_tag="VUR46_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5455914.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSENVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(22124..22720)
                     /locus_tag="VUR46_000421"
     CDS             complement(22124..22720)
                     /locus_tag="VUR46_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4190 domain-containing protein"
                     /protein_id="HET5455915.1"
                     /translation="MKQERKVLGILAIIFGALALLGSWMPIINNFSFILAILALIFGL
                     IGFAVNRKRPKTLAIIGTVLAVVSIAIVLVTQAMYAKSLKELGKNVEETVSSVSSSIE
                     SSQKEEDAKFNWTKEQFDALQVGDIINYGAGGTNYDDVASVHGEPNNVTTSSVNDHDS
                     KTVSYTSTGSKYKSVILSFSKQDDGSFLLTSKVSSGLE"
     gene            complement(22772..23152)
                     /locus_tag="VUR46_000422"
     CDS             complement(22772..23152)
                     /locus_tag="VUR46_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HET5455916.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTLSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLSLVN"
     gene            complement(23163..23330)
                     /locus_tag="VUR46_000423"
     CDS             complement(23163..23330)
                     /locus_tag="VUR46_000423"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455917.1"
                     /translation="MNHVQVKRPKENNSEYDYMLRLSNESIHQFEQKKKRQESQLKSY
                     PAIKSYYRVAN"
     gene            complement(23327..23803)
                     /locus_tag="VUR46_000424"
     CDS             complement(23327..23803)
                     /locus_tag="VUR46_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455918.1"
                     /translation="MTLAKLHFNDQGNLNGGILTNISLAQIQSTLVDNFPNSTTRTRN
                     FQALSTFLKNLDSNIITRIWLDGSFCTQKENPKDIDVLLFFKHSPDIEKYLKDIKEKA
                     STCLDIYQIGDKDHIEKTRPIYSHMAHNETYWMGQFGFDRNRNHKGIIELKTENLK"
     gene            complement(24079..24318)
                     /locus_tag="VUR46_000425"
     CDS             complement(24079..24318)
                     /locus_tag="VUR46_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455919.1"
                     /translation="MTITINFTEKNSYITDYLNKHGINTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPNPKTYTTDELLESLGMTREDIA"
     gene            complement(24318..24686)
                     /locus_tag="VUR46_000426"
     CDS             complement(24318..24686)
                     /locus_tag="VUR46_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5455920.1"
                     /translation="MFQTFDRIKELAKKQGLSINSLEEKLGYSRNTIYNLKSSKPSTE
                     RISEIADYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            24987..25178
                     /locus_tag="VUR46_000427"
     CDS             24987..25178
                     /locus_tag="VUR46_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455921.1"
                     /translation="MPNMDGGRQKIRDYLKEHNLTMATLAVQYSMARQDVTNILNGKL
                     KNPQANQFIARVIEDFKIR"
     gene            25205..25384
                     /locus_tag="VUR46_000428"
     CDS             25205..25384
                     /locus_tag="VUR46_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455922.1"
                     /translation="MEEDIRVHMPYEVFKNLLVRAGRIKREEGKQITWTNNTAPFTKE
                     QRREIDELYEQFAED"
     gene            complement(25360..25911)
                     /locus_tag="VUR46_000429"
     CDS             complement(25360..25911)
                     /locus_tag="VUR46_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455923.1"
                     /translation="MSEVFTTTLISVGATVLTNLIIHGFAYQQKKIENKNKLEEKKVD
                     FLNTQLSQDRDLYISTFQNFASISGKTVSYVESRLDDAPPIDLDIITNFDDIFYKTYL
                     FLDSDEEQKKFIYFRNVLRYQAGYPHPDGLYIWDVQFEEQSYDPDTIEEPRYIFDRLN
                     ECLLIANKHINDKLHIQSSANCS"
     gene            26159..26503
                     /locus_tag="VUR46_000430"
     CDS             26159..26503
                     /locus_tag="VUR46_000430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455924.1"
                     /translation="MTDRELFKLPEDYVESTGLDKITFEVPFELFTKILKGYGHKLAW
                     EDFRQIKIHPSTRTKKTVGQCQFLFSIWMNDHLKPAIKPSKELQKEPVRKTKKQKRLH
                     KLAQNLLHRMKG"
     gene            26670..26873
                     /locus_tag="VUR46_000431"
     CDS             26670..26873
                     /locus_tag="VUR46_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455925.1"
                     /translation="MRPKRYPYSGKKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYKAIHDTSQVTQ"
     gene            complement(27028..27195)
                     /locus_tag="VUR46_000432"
     CDS             complement(27028..27195)
                     /locus_tag="VUR46_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HET5455926.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            27312..27455
                     /locus_tag="VUR46_000433"
     CDS             27312..27455
                     /locus_tag="VUR46_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455927.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            27452..27622
                     /locus_tag="VUR46_000434"
     CDS             27452..27622
                     /locus_tag="VUR46_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455928.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAIEARLNQKADQLKLDDLD
                     LEIISSRLEKVI"
     gene            complement(27615..27854)
                     /locus_tag="VUR46_000435"
     CDS             complement(27615..27854)
                     /locus_tag="VUR46_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455929.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMANPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            27973..28245
                     /locus_tag="VUR46_000436"
     CDS             27973..28245
                     /locus_tag="VUR46_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455930.1"
                     /translation="MEVVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETRKKMRSAG"
     gene            28242..28436
                     /locus_tag="VUR46_000437"
     CDS             28242..28436
                     /locus_tag="VUR46_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455931.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEK"
     gene            28433..28624
                     /locus_tag="VUR46_000438"
     CDS             28433..28624
                     /locus_tag="VUR46_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455932.1"
                     /translation="MMEYIYLVIIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMN
                     LRNSDKQFTYDVEPPEGLK"
     gene            28636..28977
                     /locus_tag="VUR46_000439"
     CDS             28636..28977
                     /locus_tag="VUR46_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455933.1"
                     /translation="MTQAEQIREYYREHPAASCDEVAEVVGTTKSNVSANLAKDIKAG
                     RCVRLEDKSYDYSPYFNHTQALTELVDWKNDTRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            28978..29208
                     /locus_tag="VUR46_000440"
     CDS             28978..29208
                     /locus_tag="VUR46_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455934.1"
                     /translation="MVRNKLTDLTNTLFAQLETLDDRDLTADELKTELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            29222..29944
                     /locus_tag="VUR46_000441"
     CDS             29222..29944
                     /locus_tag="VUR46_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET5455935.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTTYTKTQIGEVRRRLGLPVGKV
                     YQGKLLTKEQHDYLVSIQKNKISRDVANEMNLKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKTGIGLTKLTNKIREVEKNG"
     gene            29937..30419
                     /locus_tag="VUR46_000442"
     CDS             29937..30419
                     /locus_tag="VUR46_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HET5455936.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKTDTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNITGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAKLVRTEKLVIK
                     "
     gene            30419..30778
                     /locus_tag="VUR46_000443"
     CDS             30419..30778
                     /locus_tag="VUR46_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455937.1"
                     /translation="MELMNKTRVTDSLAVVIGLESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPECKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            30778..31263
                     /locus_tag="VUR46_000444"
     CDS             30778..31263
                     /locus_tag="VUR46_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455938.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            31226..32419
                     /locus_tag="VUR46_000445"
     CDS             31226..32419
                     /locus_tag="VUR46_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HET5455939.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YRKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKSV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            32437..32754
                     /locus_tag="VUR46_000446"
     CDS             32437..32754
                     /locus_tag="VUR46_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455940.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            32754..33580
                     /locus_tag="VUR46_000447"
                     /pseudo
     CDS             32754..33580
                     /locus_tag="VUR46_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            33600..34106
                     /locus_tag="VUR46_000448"
     CDS             33600..34106
                     /locus_tag="VUR46_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455941.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            34279..35100
                     /locus_tag="VUR46_000449"
     CDS             34279..35100
                     /locus_tag="VUR46_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HET5455942.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTASEIE
                     RFWDGYPNANIALRTTNFFVIDIDKHGKENGFESLKKWEHLNLIEPTLQAKTASGGKH
                     LLYFKRDDEPITQMIKFLPGVDIKAHENNYIIVAPSATENGQYEWDLEKSAEGGTIVT
                     PSRDLIRAIKKQYGKTHGYRYDGKDGLRDLARRSQTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPNPLPEKEMMRTIESMIKKDRR"
     gene            35103..36440
                     /locus_tag="VUR46_000450"
     CDS             35103..36440
                     /locus_tag="VUR46_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET5455943.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMERATEKWDGRNRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQKEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKN"
     gene            36740..36895
                     /locus_tag="VUR46_000451"
     CDS             36740..36895
                     /locus_tag="VUR46_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455944.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            36892..37365
                     /locus_tag="VUR46_000452"
     CDS             36892..37365
                     /locus_tag="VUR46_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET5455945.1"
                     /translation="MNKQELIEKYKELENSSFDIAAIVVCQLILKDLEQLDEPKPVKV
                     QQFVADFIAEQKKLGHTLSYSIDASMSDIVAEWYWDNSELFALAWIFGYEVEEEKRYT
                     VVTKATKQPLYYNAMDKKLFFSMGGLATKFTRKQLKEADLGWVFDCEGIEIEEVE"
     gene            37365..37538
                     /locus_tag="VUR46_000453"
     CDS             37365..37538
                     /locus_tag="VUR46_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455946.1"
                     /translation="MEDEQNILETQLILGKQVLEIVLDLLKDDSKIGVVLPLNINDRE
                     FTITVEKEVTDRD"
     gene            37601..38491
                     /locus_tag="VUR46_000454"
     CDS             37601..38491
                     /locus_tag="VUR46_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET5455947.1"
                     /translation="MKFLNLFAGIGGFRLGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRRERTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAINSYHENNHLSDGFRIRKLTPKECWRLQGFPDWTFDKAQEVNSNSQLY
                     KQAGNSVTVNVIAAIAKELS"
     gene            38592..39008
                     /locus_tag="VUR46_000455"
     CDS             38592..39008
                     /locus_tag="VUR46_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455948.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKEIVTQQVYFESGLAV
                     ERDIYCYDFDDIELMQSTGLKDKNGKEVFVGDIIKCTRGCLHEVYLEKEYGGTFIGGM
                     PSIYLKGLLNGYAWTEDEEIIDNVYENPELLEVTHE"
     gene            39001..39180
                     /locus_tag="VUR46_000456"
     CDS             39001..39180
                     /locus_tag="VUR46_000456"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455949.1"
                     /translation="MNKRQRKKKILNGLNKEERYHRTHCPVCDSEAGLFDRYFNTYGF
                     CSEYCGYEYYGISRL"
     gene            39201..39515
                     /locus_tag="VUR46_000457"
     CDS             39201..39515
                     /locus_tag="VUR46_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455950.1"
                     /translation="MTLFDEMQQLSSESHAKWFERYFEKYNLEQKLKTSAQKGYTGYL
                     INVWSVRDEYLRNRLGDERTLEALRELLGAGFTVKYKLYLSKNIFTGQDFVSNKKIHI
                     TW"
     gene            39590..40051
                     /locus_tag="VUR46_000458"
     CDS             39590..40051
                     /locus_tag="VUR46_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET5455951.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWSDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLQLGRMINRLKNPKHRTILRMTYINK
                     MYVDDICDSMRGISSPTYYRLKKQAVKELDIILSELIVNDSNCTGMKSKIC"
     gene            40076..40158
                     /locus_tag="VUR46_000459"
     tRNA            40076..40158
                     /locus_tag="VUR46_000459"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:40107..40109,aa:Tyr,seq:gta)
     gene            41283..41723
                     /locus_tag="VUR46_000460"
     CDS             41283..41723
                     /locus_tag="VUR46_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HET5455952.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDEQLKQLDSEKIADQQEVLSYLTSVMRGETQEQTLISIGELGQTITD
                     INVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            41701..42999
                     /locus_tag="VUR46_000461"
     CDS             41701..42999
                     /locus_tag="VUR46_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HET5455953.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWIKRVFFDEETSRADTFATTTTYRCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFDKDELLRDLANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGITRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            43011..44480
                     /locus_tag="VUR46_000462"
     CDS             43011..44480
                     /locus_tag="VUR46_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET5455954.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIRNTESSHLKKLKSYYL
                     GKHAILKHTRRNVNAPNYQTVANHAKDIADMATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGLTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMSLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQD
                     NTKPEDEVEDEESGVLGEEESQSDLPTDGQGRKAGRPVR"
     gene            44389..45940
                     /locus_tag="VUR46_000463"
                     /pseudo
     CDS             44389..45940
                     /locus_tag="VUR46_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            46254..46778
                     /locus_tag="VUR46_000464"
     CDS             46254..46778
                     /locus_tag="VUR46_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HET5455955.1"
                     /translation="MSEEINATVSTESTETVDTQENVDTVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQT
                     VQQEVTEKWRKDFL"
     gene            46801..47826
                     /locus_tag="VUR46_000465"
     CDS             46801..47826
                     /locus_tag="VUR46_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HET5455956.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKKSAQGKVVNRAKAWKTGTTYKKGESVTHADKVYVAVKDISNSATAPDTDTTNW
                     KEKTGKK"
     gene            47836..48024
                     /locus_tag="VUR46_000466"
     CDS             47836..48024
                     /locus_tag="VUR46_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455957.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNFASNGVA
                     ISDVLEEILPEPEFFEED"
     gene            48026..48337
                     /locus_tag="VUR46_000467"
     CDS             48026..48337
                     /locus_tag="VUR46_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HET5455958.1"
                     /translation="MSIELLKKMTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            48318..48656
                     /locus_tag="VUR46_000468"
     CDS             48318..48656
                     /locus_tag="VUR46_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455959.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYVKEAETIRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            48631..49143
                     /locus_tag="VUR46_000469"
     CDS             48631..49143
                     /locus_tag="VUR46_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET5455960.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNAAIKVVQADAR
                     RLAPARDGELIISIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQI"
     gene            49143..49511
                     /locus_tag="VUR46_000470"
     CDS             49143..49511
                     /locus_tag="VUR46_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455961.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWENFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            49514..49927
                     /locus_tag="VUR46_000471"
     CDS             49514..49927
                     /locus_tag="VUR46_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5455962.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELKYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELTFVDGIGG"
     gene            49932..50312
                     /locus_tag="VUR46_000472"
     CDS             49932..50312
                     /locus_tag="VUR46_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455963.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKGKKASKKKMTVVE"
     gene            50351..50701
                     /locus_tag="VUR46_000473"
     CDS             50351..50701
                     /locus_tag="VUR46_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455964.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIAELWEYAPDLFVEEKQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            50688..51233
                     /locus_tag="VUR46_000474"
                     /pseudo
     CDS             50688..51233
                     /locus_tag="VUR46_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            52573..54294
                     /locus_tag="VUR46_000475"
                     /pseudo
     CDS             52573..54294
                     /locus_tag="VUR46_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841383.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            54303..54653
                     /locus_tag="VUR46_000476"
     CDS             54303..54653
                     /locus_tag="VUR46_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455965.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMLTQEEMSQLLNAVSAVFFEVSYPDPVKGQTTGTFYVGDRTAPSYSFTEK
                     FKPWSGAKFNLVER"
     gene            54658..57855
                     /locus_tag="VUR46_000477"
     CDS             54658..57855
                     /locus_tag="VUR46_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HET5455966.1"
                     /translation="MDALIRRQFDRAMFAKDRTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDILHPEIGLLVGTTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLYGL
                     TKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADKDSDQKVDKIKKDFNDQVELAKARAEEVKQE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEVKRIGLDSVARLGAFKSQ
                     TTSAQTALSGDLDALKQTVTSEVNQASEYRRTTTEVLSRMTGQMDGFATKSEVRQDVA
                     GLTETFAKLKTDTNNLISGAKSEITLAKTEFQKTADGLSAKMSAVERYVNQDGQRQEA
                     LQRYTREESARQVSAVREQISRDYVGKSAYQEDVRGLERRFSAISTQTNNDIARKIAQ
                     YKQTVDGQFASITSQIAGKANQTDFQRVKETSKLYERILGNSKNGIANTIARMAMTHQ
                     LFQVEVSKNDHLKTVQRQLAGSWSVQNINSAGDLISGINLGANGHNRFVGKLTHITGE
                     TLIDRAVIKSAMVDKLKTANFEAGSVTTTILDAEAVTADKVRFDAAFIRKMTANDAFI
                     DQLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTIGRFAQGRGRWISGINQFSVGMGN
                     GEGGGYNGENTAFWANWGYSWNSPGPNAWYVTTSGNMYCRNGADFHGKVDFSNSSRAN
                     FYGNTTFSRSPVFSNGIELGSKDVFGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSD
                     RRLKENITDTAVKALDKINRLRMVAFDFIESKKHEEIGLIAQEAETIVPRIVSRDPEN
                     PDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA"
     gene            57852..57968
                     /locus_tag="VUR46_000478"
     CDS             57852..57968
                     /locus_tag="VUR46_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HET5455967.1"
                     /translation="MNNNMLTNIALKAIQELALENRKRTDRLENLENERRTA"
     gene            57949..58152
                     /locus_tag="VUR46_000479"
     CDS             57949..58152
                     /locus_tag="VUR46_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455968.1"
                     /translation="MNAEQLNQALQMTISEMSTTSTNSMITSNVLSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            58155..58505
                     /locus_tag="VUR46_000480"
     CDS             58155..58505
                     /locus_tag="VUR46_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455969.1"
                     /translation="MAKTIQNTDNLLDLTKITEPFDLASALRYMKESGEFIRCKNVND
                     DFYMYRDVQKRPVFVNGRRQFKDVETVWAFNQWGGTITTINVAILLNQEFYIMKFDAE
                     GNPDWTDPTVEPKE"
     gene            58514..58813
                     /locus_tag="VUR46_000481"
     CDS             58514..58813
                     /locus_tag="VUR46_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455970.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            58817..59149
                     /locus_tag="VUR46_000482"
     CDS             58817..59149
                     /locus_tag="VUR46_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET5455971.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            59153..60109
                     /gene="lytA"
                     /locus_tag="VUR46_000483"
     CDS             59153..60109
                     /gene="lytA"
                     /locus_tag="VUR46_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET5455972.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(60362..61330)
                     /locus_tag="VUR46_000484"
     CDS             complement(60362..61330)
                     /locus_tag="VUR46_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET5455973.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFTPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            61466..62323
                     /locus_tag="VUR46_000485"
     CDS             61466..62323
                     /locus_tag="VUR46_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET5455974.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKTIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            62310..63089
                     /locus_tag="VUR46_000486"
     CDS             62310..63089
                     /locus_tag="VUR46_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455975.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEALPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            63113..64465
                     /locus_tag="VUR46_000487"
     CDS             63113..64465
                     /locus_tag="VUR46_000487"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET5455976.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGELLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     KNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKKTGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            64539..64913
                     /locus_tag="VUR46_000488"
     CDS             64539..64913
                     /locus_tag="VUR46_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET5455977.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQYDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            64915..65763
                     /locus_tag="VUR46_000489"
     CDS             64915..65763
                     /locus_tag="VUR46_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5455978.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASSQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            66040..66807
                     /locus_tag="VUR46_000490"
     CDS             66040..66807
                     /locus_tag="VUR46_000490"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET5455979.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            66819..68003
                     /locus_tag="VUR46_000491"
     CDS             66819..68003
                     /locus_tag="VUR46_000491"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET5455980.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSRDKLNRLFDLETDFTFESSEQAWSALLWALEIENAQSFLKFWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            68000..69871
                     /locus_tag="VUR46_000492"
     CDS             68000..69871
                     /locus_tag="VUR46_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5455981.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHNLKKELSGGVAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQVKDRIGIVGDNGVGKSTLLNLIAGSLESTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKTFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIEALEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(70014..71198)
                     /gene="mntE"
                     /locus_tag="VUR46_000493"
     CDS             complement(70014..71198)
                     /gene="mntE"
                     /locus_tag="VUR46_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET5455982.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            71502..74198
                     /locus_tag="VUR46_000494"
     CDS             71502..74198
                     /locus_tag="VUR46_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET5455983.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVLLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKARDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHILTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            74211..75002
                     /gene="yghU"
                     /locus_tag="VUR46_000495"
                     /pseudo
     CDS             74211..75002
                     /gene="yghU"
                     /locus_tag="VUR46_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
     gene            75119..75529
                     /locus_tag="VUR46_000496"
     CDS             75119..75529
                     /locus_tag="VUR46_000496"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET5455984.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKCYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            75541..77136
                     /locus_tag="VUR46_000497"
     CDS             75541..77136
                     /locus_tag="VUR46_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5455985.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            77202..77366
                     /locus_tag="VUR46_000498"
     CDS             77202..77366
                     /locus_tag="VUR46_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET5455986.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            77445..78173
                     /gene="yaaA"
                     /locus_tag="VUR46_000499"
     CDS             77445..78173
                     /gene="yaaA"
                     /locus_tag="VUR46_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET5455987.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(78540..79088)
                     /locus_tag="VUR46_000500"
     CDS             complement(78540..79088)
                     /locus_tag="VUR46_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5455988.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQVVGDFTAARVNDSAWADGKL
                     VLEETVLNSLDKQAQDLVNAIK"
     gene            79409..79897
                     /locus_tag="VUR46_000501"
     CDS             79409..79897
                     /locus_tag="VUR46_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET5455989.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            79894..81081
                     /locus_tag="VUR46_000502"
     CDS             79894..81081
                     /locus_tag="VUR46_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5455990.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     ENN"
     gene            81074..81439
                     /locus_tag="VUR46_000503"
     CDS             81074..81439
                     /locus_tag="VUR46_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5455991.1"
                     /translation="MIDHFEIKVKDLQILEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            81455..82801
                     /gene="asnS"
                     /locus_tag="VUR46_000504"
     CDS             81455..82801
                     /gene="asnS"
                     /locus_tag="VUR46_000504"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET5455992.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            82954..83244
                     /locus_tag="VUR46_000505"
     CDS             82954..83244
                     /locus_tag="VUR46_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET5455993.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIKDFREGLYHIVNVEANDDVALKEFDRLSKINADILRHMIVKIDA"
     gene            83256..83726
                     /gene="ssbA"
                     /locus_tag="VUR46_000506"
     CDS             83256..83726
                     /gene="ssbA"
                     /locus_tag="VUR46_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET5455994.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTVGAYSAPTANYSAPTNSVPDFSRDENPFGATNPLDISDDDLPF"
     gene            83758..83997
                     /locus_tag="VUR46_000507"
     CDS             83758..83997
                     /locus_tag="VUR46_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET5455995.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
BASE COUNT        26126 a        15091 c        19126 g        23695 t
ORIGIN      
        1 cacaaaagag ggaaaagaca gatttggtgt ttcgtagaag taaaaacagc ccaaagaggg
       61 ctgtcagtta agatgagatt tcaacttaaa tcgcaaacaa gtcattcaag ttctcagcca
      121 aggttgggtg agtgaagatt tgttttgtga agtaagtgta aggaatcttg ttgtccatag
      181 caacagtaat gatgttgatg atttcttgag aaccttctga gaagatgctt gcaccaagaa
      241 tttcttttgt ttcagtatta acaacagctt tgaaagctcc gcgaaggtct ccatttacgt
      301 gaccacgagg catggctgca acagggattt ctttcactgc gtatggaagt ttcaaatcag
      361 ctgcttggct ttcagtcaaa ccaacttgtg aaagtgcagg tgtgatgaac atagtatttg
      421 gcacattgag acggtcctca agtgtgtagc tgccatctcc agcaaggtag ctataaacaa
      481 cacggaagtc atcaagtgaa atgtaagtaa attgaagacc accgttgaca tctccaactg
      541 caaagacacc aggaacgttt gtttgacagt gtttatctac tttaatagcg ccacgttcag
      601 ttagttcaat atctgtattt tcaagttgaa gtggttctac atttggtttg cgtccagttg
      661 cgtagagaag ggcgtcgaaa cggtaagttt cgtcttcagt tacgacaagc acttggtcac
      721 cgtcgttttt aatttcagta gtatggatat tttgaagcaa ttcaataccg tcttcttcca
      781 ggtattgttt agcaagagct gcgatggaag gttctgcacg aggtaggaat gtatccaagg
      841 catctaggac tgtaaccttg cttcctagtt tattgtaaag gccagcaaat tcaagaccga
      901 tatttccgcc accaaggact ccaagttttt caggcaattt atccaagctt tggatacctg
      961 ttgagtcaaa gacgtttttg cttgtagcaa gtccagggat tggcaagacg tttgaaacag
     1021 caccagtgtt gatgacgata gtttcagcag tcaattcttg tttttcatca ccagcttgga
     1081 tttcgatgac tttatttgaa aggaagtgag cttcagcatc aaagatattg acgccagtac
     1141 cagcaacagt cgtatagttt ttaccgttga ggcgaccagt gatcgtgttt ttggtagcaa
     1201 tgacttcttc aaaagacaag tctttctcag cagcaaccag caaagtttta gttgggatac
     1261 aaccgatgtt gatacaagtt ccaccgtaca tagctttgct acgttcaacg agggcaactt
     1321 ttttgccagc tgaagccaat ttaccagcta gtgttttacc agctttacca aatccgataa
     1381 cgattaaatc ataagttaac atttagaatt cctcctattc gaattacatt ctagcacaag
     1441 aaaaaaactt ttgcacaatt ctgctacgaa aaagacagaa aaagataaaa acgctttcca
     1501 gacaaaaaac tagtaatttt ttaacaagct tgataaacta aaatcctatc tatttttata
     1561 taagaaagaa taaatgttcg aaaataggag gttttatgaa atcgaatcgt tatattattg
     1621 cctttgctgg ggtcatttta cacttaatgc tgggttcgac ttatgcctgg agtgtttatc
     1681 gtaaccctat tattgaaaaa acgggatggg atcaggcttc tgttgccttt gcctttagtc
     1741 tagcaatctt ttgtttgggc ttatcggctg catttatggg gcgtttggta gaaaaatttg
     1801 gtccaaaagt catgggaagt ctatctgctt ttctatacgc aggtggaaat atcttaacag
     1861 gatttgcaat agaccgtcag gagctgtggt tgttgtatct cgcttatggc attttaggtg
     1921 ggcttggttt gggagcaggc tatattaccc ctgtgtcgac gattataaaa tggtttcctg
     1981 ataaacgtgg tctcgcaaca ggtttagcga ttatggggtt tggttttgct tctttattga
     2041 ctagtcccat agcgcaacac ctcatcgcag gggtagggct tgtagaaact ttttatattt
     2101 taggagcaag ttactttatt atcatgctcc tagcttcaca attcattaag cgtccaaatg
     2161 agcaagagct tgcaatttta tcttcttcag ggaaagaaaa aacagcctct ttgacgcaag
     2221 gaatggctgc aaatcaggct ctaaaaagca atcggtttta tatgctttgg attattttct
     2281 ttatcaacat agcttgtggt ttaggcttaa tttcagcggc atcgccaatg gcacaggaga
     2341 tggctggctt gtctacaagt catgcagcag taatggtggg tgttttgggg attttcaatg
     2401 gatttggtcg cttgctctgg gcgagtttgt ctgattatat cggtcgccct ctaaccttta
     2461 gtatattact gcttgtcaat cttttctttt ctctctcact ttggctcttt acagattccg
     2521 ttttatttgt agttgctatg tctattttga tgacttgcta tggagctggt ttttctttga
     2581 ttccagctta tctcagtgat atttttggaa ccaaggaatt ggccgctcta catggttata
     2641 ttttaacagc ttgggcaatg gctggtttag cgggacctat tttattagca gagacttata
     2701 aaatggctca ttcgtacaca caaaccttgt tcgtttttct cattttatac agtattgcct
     2761 tggctttgtc ttattatcta ggtcgttcaa tcaaaaaaga aagtcaaaaa ccgcttacat
     2821 gattttctgt agaaatgggg ctatcttttg ctctggtctt gtgttatact agataggttg
     2881 caaagaaaac agtacttttc ttttgtggaa aagaagcaac acgattttat atctagttat
     2941 atgaaaatac gtcataaaaa gaaaagtata aactaagccc tatagggtgg cttcgcacca
     3001 cctttagaaa gaagaataac gtgaaattta atgaattaaa cttgtctgct gatttgctgg
     3061 cagaaattga aaaagctggt tttgtagaag ctagtcctat ccaagaacaa actattcctt
     3121 tggcccttga aggcaaggat gttatcggtc aagctcagac tggtacagga aaaactgcag
     3181 cctttggctt gcctaccctt gaaaaaatcc gtacagaaga agcgactatc caagccttgg
     3241 tcatcgctcc aactcgtgaa ctagctgtcc aaagtcaaga agaactcttc cgctttggtc
     3301 gtagtaaggg agtcaaagtc cgttcagtat atggcggatc aagcattgaa aaacaaatta
     3361 aggctcttaa atctggtgcc catatcgtgg tgggaactcc aggtcgcctc ttggatttga
     3421 ttaaacgcaa ggccttgaaa ttacaaaaca ttgaaaccct tatccttgac gaagcggatg
     3481 aaatgcttaa catgggcttc cttgaagaca tcgaagccat tatttcccgt gtacctgaga
     3541 accgtcaaac tttgcttttc tcagcaacta tgccagatgc catcaaacgt atcggtgttc
     3601 agtttatgaa agcccctgaa catgtcaaga ttgcggctaa ggaattgaca acagaattgg
     3661 ttgaccagta ctatatccgt gttaaggaac aagaaaaatt tgacaccatg actcgtctca
     3721 tggatgtggc acaaccagaa ctcgctattg tatttggtcg taccaaacgc cgtgtggatg
     3781 aattgactcg tggtttgaaa attcgtggct tccgtgcaga aggaattcat ggcgacctag
     3841 accaaaacaa acgtcttcgt gtccttcgtg actttaaaaa tggcaatctt gatgttttgg
     3901 ttgcgacaga cgttgcagcg cgtggtttgg atatttcagg tgtgacccat gtctacaact
     3961 acgatattcc acaagatcct gagagttatg ttcaccgtat cggtcgtaca ggtcgtgctg
     4021 gtaagtcagg tcaatctatt acttttgttt ctccaaacga aatgggttac cttcaaatca
     4081 ttgaaaactt gactaagaaa cgcatgaaag gtctcaaacc tgcaagtgta gaagaatcct
     4141 tccaatcaaa aaaacaggta gctctcaaga aaatcgaacg tgattttgta gatgaaacca
     4201 ttcgtgccaa ctttgagaaa tttggtaagg atgctcgcaa attggctgct gagtttactc
     4261 cagaagaatt ggcaatgtat atcttgagtc tgacagtcca agatccagat agccttccag
     4321 aagtggagat tgcacgtgaa aaaccactac cgtttaaacc atcaggtaat ggtttcggtg
     4381 gtaaagctaa gggaggtcgt ggaggccgtc gtggggacga ccgtcgagag cgtgatcgcc
     4441 gtggcaatgg tcgccgtgat gagttcaaaa aaggaagtcg tggcaacgat cgttttgata
     4501 aggaaaaacg ttactgtaag gataataaaa aaccacgcaa tactttaagc gaaaagcaaa
     4561 caggctttgt tattcgtaac aagggcgata aataagaaaa agcggttcaa aatgaatcgc
     4621 ttttttatat aaggagaccg aatgtgaaaa agacaaataa atttattata ttatattgta
     4681 taatattatg atatgtaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaac
     4741 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
     4801 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
     4861 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
     4921 gttgcaggat gagcttcctt acaacgctat tacgcgtcag ttagcggata ttattcattg
     4981 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
     5041 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagata actacgttca
     5101 aggggctaat atgatttacg aaacagaagc aaacttgcct gttgagcatg atatgagtat
     5161 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
     5221 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
     5281 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
     5341 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
     5401 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
     5461 tgaaggacag ttgactgcgt cagtgattgc agatcgtatc ggaattactc gctctgtgat
     5521 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
     5581 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
     5641 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
     5701 gggaagctga cagcaggtgc tccagctcag gcgatttcgg atgccatcag caaggtaact
     5761 cgattagctt ttgaacgagg agattatatc ttctttacca ttgatgctca tgaagaaaac
     5821 gattgtttcc atccagaaag taaactattt cctcctcata atttgattgg gactggtgga
     5881 cgaaatttat acggagattt ggggatcttt tatcaagaac atgattcaga cagtcgtgtc
     5941 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
     6001 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
     6061 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
     6121 gcttccattt ggcctgaaaa tcatcaattt tccctaggtc atttcaaaaa tacactcgga
     6181 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aatctggttg gcgaaaatga
     6241 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
     6301 gacgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
     6361 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
     6421 tgtatttctc taaaaaatta gcatccagtc aaatgtagtg gagaatcatc gaaaatatga
     6481 gaaaactgat ccttgtttct gcttttgtca tagaagaata atcaagatta tcttcttcaa
     6541 attctccgat attctctaaa gttttgtgca agttgcacag aacttgttta tttttttggt
     6601 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
     6661 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
     6721 aacactactc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
     6781 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
     6841 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
     6901 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
     6961 acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
     7021 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
     7081 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
     7141 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
     7201 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
     7261 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
     7321 gtacaggtac tatcggacgt gtagaacaaa tcggtactcc tcaagaagtt tacaaaaatc
     7381 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaccgtga
     7441 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
     7501 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
     7561 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
     7621 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
     7681 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
     7741 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
     7801 aaaataaata aaattcaaag cactacaaga aaagatatct ctttatcaat tgtagtggag
     7861 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
     7921 atattatgca tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg
     7981 tcaacgtcgc cttgccgtac gtatgattac tgacttcgtc agttttatct gcaacctcaa
     8041 agctgtactt tgagcagctt acggctagtt tcctagtttg ctctttgatt tccattgagt
     8101 attatttgtg ggtaccatct acaagtgaag ctatatgcgt aaactacgtg agcaattgaa
     8161 ttcgaactag agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg
     8221 attctagttt atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg
     8281 aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg
     8341 gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg
     8401 attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga
     8461 gttggcacag cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga
     8521 agtggctaaa aaatctgctg gaacggcagg tgttgctcat ttaattagtt ttgaaagagc
     8581 aaatgcaatg aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat
     8641 gctgactatg caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt
     8701 aaaacctgga ggtcttctct tgacacatga tgtgcttctt aaggaagcta aagagtctat
     8761 cagacaggaa ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatgcttg
     8821 ggaacaggtg atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac
     8881 attaatgaaa ttatcgggta tgatttatga cgaaggtttg ctaggaactt tgaaaatttg
     8941 tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc
     9001 taagaataaa cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta
     9061 gataattatt gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga
     9121 gtaaaaaact ttgaaagaaa gaaaaagatg aatttaaaag attacattgc aacaattgaa
     9181 aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc tgatggaaat
     9241 gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa agtcgacatg
     9301 atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt tgagttggga
     9361 attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat ttctgctgac
     9421 tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat taagccaggt
     9481 caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa ggcaactatc
     9541 gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt tgaattggat
     9601 gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat gcattattaa
     9661 tgaaaacagt ccttagggct gttttctcta cactaggata taaaaataga ctataactag
     9721 ttagagaaaa actataattg aaaactatat cttcttgcag tataataaaa ggactaagtg
     9781 tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt aggagagggt
     9841 tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga cagagaatat
     9901 ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga agattttaat
     9961 tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc acttggctaa
    10021 tacaccccta caactggata ttgattttct ctatatggag agccaccgtt ctaaaacaac
    10081 tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg atgagtattt
    10141 tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg aagtggacta
    10201 ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt cgacccttca
    10261 tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa aataccagat
    10321 ggacagtaag ctatcaggta tttatcctca gaacacccta aaagagggtc accttctatt
    10381 tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga tttctaagga
    10441 agagattctg aataagacca atctcgagat tttgtcagaa ggtcctcagg ttggggtttc
    10501 gattttagcc agtcgtgatt tgcgagaaat ttatagtttt gggcatttgg aatatgaccg
    10561 tgataccttg gcaaaagagt atttcagaga ttgtgatgca ggtttagctc ctcatattcc
    10621 agaaaattat tttaaggatg atgatgttaa tcagacccct tgtctttgtt ggtcttcatc
    10681 ggcagccctc tttttcagta actgggtgaa ctatgcggtc tatcaggaga cgccttttga
    10741 ctggagaaaa atagaagatg atgcatctgc atatgggtat ttataagagg aattatgaca
    10801 tatttagacg cttttaaatc agggaacttg gttttaccga gtgcccttct cttgcatttt
    10861 aaggaactct ttccttccag cgatgatttt ctggtctggc aatttttcta tttgcaaaat
    10921 acgacaggct tagaagaaat gtcaccaagc cagattgctg aaaggattgg caaggaaatt
    10981 tcggatgtca accagtccat ctctaatctg acggagaggg gactgcttca gtaccgtact
    11041 atcgaattaa atggtgaaat cgaattgctt tttgatgcta gtttggcttt ggaacgtttg
    11101 gatgatttgc ttggagtcgc tcattcgagt tcagaccagt tgacacctca aaatcagctc
    11161 aaagatttgg tagaaacctt ccaacaggag ttgggacgct tgttgacacc ttttgagatt
    11221 gaagatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat taaggaagct
    11281 cttcgtgaag ctgttttgaa tggaaaagca aactggaagt acattcaggc gattttgaga
    11341 aactggcgcc atgaaggtat caaaagtgtg gctcaaatcg aggctaagcg ggcagaaaga
    11401 gaagcaagca atcctcagtt gacacaggta tcagcagatt tcagaaatgc tatggatctc
    11461 tggaaggact aatccatgta agcagacttg aaatccgagt aagatttgca agctgtgttt
    11521 aattgtgata aaataaatag aaaataaatt gaaaaaagag gtatgtgaaa tgtcacgtaa
    11581 accatttatc gctggtaact ggaaaatgaa caaaaatcca gaagaagcta aagcattcgt
    11641 tgaagcagtt gcatcaaaac ttccttcatc agatcttgtt gaagcaggta tcgcagctcc
    11701 ggctcttgat ttgacaactg ttcttgctgc tgctaaaggt tcaaacctta aagttgctgc
    11761 tcaaaactgc tactttgaaa atgcaggtgc tttcactggt gaaactagcc cacaagtttt
    11821 gaaagaaatc ggtactgact acgttgttat cggtcactca gaacgccgtg actacttcca
    11881 tgaaactgac gaagatatca acaaaaaagc aaaagcaatc tttgcaaacg gtatgcttcc
    11941 aatcatctgt tgtggtgagt cacttgaaac ttacgaagct ggtaaagctg ctgaatttgt
    12001 aggtgctcaa gtatctgctg cattggctgg attgactgct gaacaagttg cagcatcagt
    12061 tatcgcttat gagccaatct gggctatcgg tactggtaaa tcagcttcac aagatgacgc
    12121 acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct gactttggcc aagaagttgc
    12181 agacaaagtt cgtgttcaat acggtggttc tgttaaacct gaaaacgttg cttcatacat
    12241 ggcttgtcca gacgttgacg gtgcccttgt aggtggtgcg tcacttgaag ctgaaagctt
    12301 cttggctttg cttgactttg taaaataatc agtaagtagc aaaagctagg tggaacagca
    12361 ttcagatgtc tgttccattt tttataggag aggaaagatt gaaaacaaaa attgtatgta
    12421 tagggctagc aagtctttgc ttacttggcg caagagtttc aggaattgcg gcagatgaaa
    12481 caagtggaag cacagtttca gaaaaatcta gtctatcaac aggaacttca tcaactagta
    12541 gcaatgaaca gagaaacagt gtctctgccc actgggatgg ggattattat gtaaaggctg
    12601 atggttctaa agctcaaagt gaatggattt ttgacaacta ctataaggct tggttttata
    12661 ttaattcaga tggtcgttac gcgcagaatg aatggcatgg aaattactac ctgaaatcag
    12721 gtggctatat ggcccaaaac gagtggcttt atgataataa ttacaagagt tggttttatc
    12781 tcaagtcaga tggggcttat gctcatcaag aatggcaatt gattggaaat aagtggtatt
    12841 acttcaagga gtggggttac atggctaaaa gccaatggca aggaagttat ttcttgaatg
    12901 gtcaaggtgc catgatgcaa aatgaatggc tttatgatcc ggcttattct gcttattttt
    12961 atctaaaatc cgatggaact tatgccaacc aagagtggca aaaagtgggc ggcaaatggt
    13021 actatttcaa gaagtggggc tatatggctc ggaatgagtg gcaaggcaac tactatttga
    13081 ctggaagtgg tgccatggcg actgacgaag tgattatgga tggtgctcgc tatatctttg
    13141 cggcctctgg tgagctcaaa gaaaagaaag atttaaatgt cggctgggtt cacagagatg
    13201 gtaaacgcta tttctttaat aatagagaag agcaagtggg aaccgaacat gctaagaaag
    13261 tcattgatat tagtgagcac aatggtcgta tcaatgattg gaaaaaggtt attgatgaaa
    13321 atgaagtaga tggtgtcatt gttcgtttgg gctatagtgg aactgaggac aaggaattgg
    13381 ctcataatat taaggagtta aaccgtcttg gaattcctta cggtgtttac ctttatactt
    13441 atgctgaaaa tgagaccgat gctgagaatg atgctaatca aaccattgaa ctcttgaaaa
    13501 aatacaagat gaacttgtct taccctatct actatgatgt tgagaactgg gaatatggca
    13561 ataagaccaa gagggctcca agtgatactg gaacctgggt caagattatc aacaaatata
    13621 tggcaacaat gaagcaggcg ggttatcaaa atgtgtatgt ctatagctat cgtagtttat
    13681 tacagacgcg tttaaaacac ccagatattt taaaacatgt aaactgggta gcggcctata
    13741 ccaatgcttt agaatgggaa aaccctcatt attcaggaga aaaaggttgg caatatacct
    13801 cttctgaata catgaaagga atccaagggc gcgtagatgt cagcgtttgg tattaagcga
    13861 tgatttgaaa gagggatgtg atagtagcac cctctttttc tttgttttat ggcagttcat
    13921 cctcgagtaa attcaagatc ttgctaggaa ataaatctta tatggtagat tgaatataga
    13981 ccgggacatt gcggttgcta aaacattttt agaaattcat ttgtctttcc taatcgactt
    14041 ggctccatct tatttcaatc tattatagtc ttggggaatt tcttcaaacc acgtcagctt
    14101 ggtcagttct acctgcgacc tcaaaacttg tacttggtta agctgggttt ggcttcctag
    14161 tttgctgatg gatttccatg gactataagc atccagacct ctttttcgtc ttctaaagaa
    14221 ttcttaaatt atcagtctat tgcaactttt ctcatgtggg tcatttggct tgcaattgtc
    14281 tttccttagt agtatactaa ggtagtaatc attaagaagt ggttacataa aaataatgaa
    14341 tgaggtaaaa taaaatggta gaattgaaaa aagaagcagc aaaagatgtc gcaacattaa
    14401 caaaagcagc gccagtaaca ttggcaaaaa caaaggaagt tttgaatcaa gctgtagctg
    14461 atttgtacgt agctcacgtt gctttgcacc aagtacactg gtatatgcgt ggacgcggtt
    14521 ttatggtatg gcatccaaaa atggatgagt acatggatgc tcttgatggt catttagatg
    14581 aaatcagcga acgattgatt acactcggtg gaagcccatt ctctacattg acagaattcc
    14641 ttcaaaatag tgaaatcgaa gaagaagctg gtgaataccg taatgttgaa gaaagcttgg
    14701 aacgtgttct agatatttat cgctacctca tcactctttt ccaaaaagcg ttggatgtga
    14761 ctgacgaaga aggcgatgat gttacaaacg atatttttgt tggtgctaag gctgaacttg
    14821 agaaaacagt ttggatgctt gccgcagaac ttggacaagc acctggtttg taagaaacaa
    14881 ggtaacatag ataaatctgt aggaaatttc ttacagattt tttctatttt gtaagctatt
    14941 ccaaaccagt ctttttttta gttttttgat aaaatagtac tatcagtgaa aaggatggaa
    15001 gcatgactaa gaaaatcgta gctatttggg cccaggatga agagggtgtg attggtaagg
    15061 acaatcgtct gccttggcat ttgccagcag aattgcagca ctttaaagaa acaactctga
    15121 atcatgctat cttgatgggg cgggtaacct ttgatggaat ggggcgtcgc ttgcttccac
    15181 aacgggagac cctgattttg acgcgtaatc cggaagaaaa gatagatggg gttgctactt
    15241 ttcaggacgt ccagtctgtt cttgactggt atcaggctca agaaaagaat ctctacattc
    15301 tcggcgggaa gcaaattttt caggcttttg aaccctacct tgacgaagtg attgtgactc
    15361 aaattcatgc tcgggtggag ggagatacct atttccccga ggagtttgac ttgtctcttt
    15421 ttgagacggt ttcaagcaaa tcttatacca aagatgagaa aaatctttat gattttacca
    15481 tccaataccg caagagaaag gaagtctaat ggaacggagt atatttggtt ttttcacagc
    15541 catgctgtgt ttggtctgct tgcttgcagg agcacaggcc tttcgtaaaa agcgctatgg
    15601 actttctgtc ctgctcttgt taaatgcctt taccaatttg gtcaatagta tccatgcttt
    15661 ttacatgacc ttattttaga tagaatgata gtatagaata gaacggaagg aaatcatgcc
    15721 tacaactagg aataatgata tgatggttta ttgctcattt tgtggcaaaa accaagaaga
    15781 agtacaaaaa ataatcgctg gcaacaatgc ttttatttgt aatgagtgcg tggagttagc
    15841 tcaagaaatt attcgagaag aattggttga ggaagtcttg gcagacttgt ctgaggtgcc
    15901 aaaaccaatt gaactcctcc atatcttgaa ccactatgta attggtcaag atcgtgccaa
    15961 gcgtgccttg gcagtggcag tttacaacca ctacaaacgt atcaacttcc acgatacgcg
    16021 tgaagagtca gaagatgtgg atttgcagaa atcaaacatt ttgatgattg gcccaactgg
    16081 ttcagggaaa actttccttg cccagacctt ggctaagagc ttgaatgtgc cttttgcgat
    16141 tgcggatgca acagctctga cggaggctgg ttatgtaggt gaggacgtgg aaaatatcct
    16201 tctcaaactc ctgcaggccg ctgactttaa tatcgagcgt gcagaacgtg ggattatcta
    16261 cgtggatgaa attgacaaga ttgccaagaa gagcgaaaac gtgtctatca cacgtgacgt
    16321 ttctggtgaa ggggtacaac aagcccttct taagattatc gagggaactg ttgccagcgt
    16381 accgcctcaa ggtggacgca aacatccgca acaagaaatg attcaagtgg ataccaaaaa
    16441 tatcctcttc atagtgggtg gtgcctttga tggtatcgaa gaaattgtca aacaacgtct
    16501 gggtgaaaaa gtcatcggat ttggtcaaaa taacaaggcg attgatgaaa atagctctta
    16561 catgcaagaa atcatcgcag aagatattca aaaatttggt attatccctg agttgattgg
    16621 acgtttgcct gtctttgcag ctcttgagca attgacggtt gatgacttgg ttcgcatctt
    16681 gaaagaacca agaaatgcct tggtcaaaca atatcaaacc ttgctttctt atgatgatgt
    16741 cgagttggaa tttgacgacg aggcccttca agagattgcc aacaaggcca tcgaacggaa
    16801 gactggggcg cgtggtcttc gttcgattat tgaagaaacc atgttagatg ttatgtttga
    16861 agtaccgagt caggaaaatg tgaaattggt tcgcattaca aaagaagctg tcgatggaac
    16921 ggacaaacca atcctagaaa cagcctagag gtgactatgg aactgaatat acacaatgct
    16981 gaaatcttgc tcagtgcggc gaataagtcc cactatccgc aggatgaact accagagatt
    17041 gccctagcag ggcgttcaaa tgttggtaag tctagcttca tcaacaccat gctgaaccgt
    17101 aagaatctgg ctcgtacgtc agggaaacct gggaaaaccc agcttctcaa cttctttaac
    17161 attgacgaca agatgcgctt tgtggatgtg cctggttatg gttatgcccg cgtttccaaa
    17221 aaggaacgtg aaaagtgggg gcgcatgatt gaggagtatc tgacaactcg agaaaatctc
    17281 cgtgcagtgg tcagtttggt ggatctccgt cacgatccgt cagcagatga tgtgcagatg
    17341 tacgaatttc tcaagtatta tgagattcca gttatcattg tggcgaccaa ggcggacaag
    17401 attcctcgtg gtaaatggaa caagcacgaa tcagcaatca aaaagaaatt aaactttgac
    17461 ccaagtgatg actttattct cttttcatct gtcagcaagg cagggatgga tgaggcttgg
    17521 gatgcaatct tagaaaaatt gtgaggaaaa gaaaatggca aaaacaattc atacagataa
    17581 ggccccaaag gctatcggac cctatgttca aggaaaaatc gttggtaacc ttttgtttgc
    17641 tagcggtcaa gttcccctat ctcctgaaac tggggaaatc gttggagaaa cgatccaaga
    17701 acagacagaa caagtcttga aaaacatcgg tgctattttg gcagaggcag gaacagactt
    17761 tgaccatgtt gtcaaaacaa cttgcttctt gagcgatatg aatgactttg ttccttttaa
    17821 tgaggtttac caaacggcct tcaaagagga attcccagct cgttcagctg tggaggtagc
    17881 tcgtcttcct cgtgatgtaa aagtcgaaat tgaagtcatc gcagagattg gataagctag
    17941 ttgaagtttg gtgttgccaa acttcttttg atataaggag aaaaagatga caaagaaaca
    18001 acttcacttg gtgattgtga cagggatgag tggcgcaggg aaaactgtag ccattcagtc
    18061 cttcgaggat ctaggttatt tcaccattga taatatgccg ccagctctct tgcctaagtt
    18121 tttgcagctg gttgaaatta aggaagacaa tcctaagttg gccttggtag tggatatgcg
    18181 tagccgttct ttcttttcag agattcaagc tgttttggat gagttggaaa atcaagatgg
    18241 tttggatttc aaaatcctct ttttggatgc ggctgataag gaattggtcg ctcgttacaa
    18301 ggaaaccaga cggagtcacc cactagcagc agacggtcgt attttagatg gaatcaagtt
    18361 ggaacgtgaa ctcttggcac ctttgaaaaa tatgagccaa aatgtggtgg atacgactga
    18421 actcactcca cgtgagctgc gcaaaaacct tgcagagcag ttttcagacc aagaacaagc
    18481 ccagtctttc cgtatcgaag tcatgtcttt cggatttaag tatggaatcc cgattgatgc
    18541 ggacttggtc tttgatgtcc gtttcttgcc aaatccctat tatctaccag aactgagaaa
    18601 ccaaacgggt gtggatgaac ctgtttatga ttatgtcatg aactatcctg agtcagaaga
    18661 cttttatcaa catttattgg ccttgattga gccgattctg ccaagttacc aaaaggaagg
    18721 taagtccgtt ttgaccattg ccatgggatg tacgggtgga caacaccgta gtgtggcatt
    18781 tgctaaacgc ttggtgcagg acttatccaa gaattggtct gttaatgaag ggcatcgcga
    18841 caaagaccgc agaaaggaaa cggtaaaccg ttcatgagaa aaccaaagat aacggtgatt
    18901 ggtggaggga ctggaattcc cgtcattcta aaaagtctgc gggaaaaaga tgtggaaatc
    18961 gcagctatcg tgacggtggc agatgatggt ggttcttcag gtgaactccg aaaaaatatg
    19021 caacagttga caccgccagg tgatcttcgt aatgtccttg tggccatgtc ggatatgcct
    19081 aagttttatg agaaggtctt tcagtatcgg ttctctgagg atgccggagc ctttgctggc
    19141 catccattgg gaaatctcat cattgctggc ttgtcagaaa tgcagggttc aacctataat
    19201 gccatgcagt tattgagcaa atttttccat acaacaggga aaatttatcc ttccagtgac
    19261 catcctttga cccttcatgc agtctttcag gatgggacag aagtggctgg agagagtcat
    19321 attgtagacc atcgaggcat aattgacaat gtctatgtga ccaatgccct aaacgatgat
    19381 acgcctctgg ccagccgtcg agtagtgcag atcatccttg aaagtgacat gattgtccta
    19441 gggccaggtt ccctctttac ctctattttg cccaatatcg tgattaagga aattgggcgg
    19501 gctcttttgg aaaccaaggc agaaattgcc tatgtctgca atatcatgac ccaacgtggg
    19561 gagacggaac actttacaga tagcgaccac gtggaagtct tgcatcgtca ccttggtcgc
    19621 ccttttatcg acactgtctt ggtgaatatt gaaaaagtgc ctcaggaata catgaattcc
    19681 aaccgttttg atgaatactt ggtgcaagtg gaacacgatt ttgtaggtct ttgtaagcaa
    19741 gtttcgcgcg tgatttcatc taacttcctt cgtctggaaa atggcggtgc cttccacgat
    19801 ggagatttga ttgtggacga gttgatgcgc attatacagg tgaaaaaatg agtttcacag
    19861 tagcaataaa agaagaaatc ctgggccaac accatctgag ctggcatgaa ttatctgcca
    19921 ttatcaaaat gtctggtagc atcggtctct cgacttcggg cttgactttg tcagttgtga
    19981 cagaaaatgc caaactggcc cgtcacctct atgagtcctt tctccatttc tatgaaatca
    20041 aatctgaaat tcgtcaccac caacggagca atcttcgcaa gaatcgcgtc tatacagttt
    20101 ttacagatga aaaggtgcag gatttgttaa gtgatttgca cttggcagac tctttctttg
    20161 gcctggaaac aggtattgat gaggcgattt tatcggatga ggaagcaggt cgtgcctatc
    20221 tctgtggcgc tttcttggca aatgggagca ttcgtgaccc tgagtcaggc aagtaccagt
    20281 tggaaatcag ttccgtttat ctggaccacg cgcaaggaat tgcctccctt ctccaacagt
    20341 ttttactgga tgccaaggtg cttgagcgca agaagggggc tgtgacctat ctccagcgag
    20401 cagaagacat tatggacttc ttgatagtaa tcggagccat gcaggcacgt gatgattttg
    20461 agagggttaa gattttgcga gaaacccgta acgacctcaa tcgggctaat aatgccgaga
    20521 cagctaatat cgctcggaca gtttctgcca gcatgaagac cattaacaat atcagtaaaa
    20581 tcaaagatat catgggctta gaaaatttgc cagtagattt gcaggaagtg gcgcaactgc
    20641 ggattcagca cccagactac tctatccagc agttagcaga tagcctcagc acccctctga
    20701 ccaaaagtgg tgtcaatcac agactcagaa aaatcaataa gatagcggat gaattataac
    20761 gatataaagc aaccccttga attatcaata tcttcaaggg gttttgttgt gttatgaaat
    20821 caaaaagggg caaccaaggg gcagaattaa aaaatagtat ctaatttatt gaccagttta
    20881 tcctccatat cttcagtagt atgagaatag atttccaaag tcatttttgc atttgagtgc
    20941 ccaactcgat ccattattga ttttattggg aggccagact ctgctaaaaa cgaaatatga
    21001 gaatgcctaa aaatatggct agataagttt ttttctattt tggcctgttt tccatatttt
    21061 tttaatatct gtatgaagca agctattgtt gtaggttgat tccatttttc aaaacagaaa
    21121 atataatcat cgcttgacaa tggctggaaa cgttcgctaa gtcgtactat ttgtctttga
    21181 atagcttcta tgacattctc tgatactttg attgtccgta ttgaatttgt agtctttggt
    21241 agcgtcttga ttttgtttac tgaatcaaaa ttacctgtga tctcaatttt gttgttttcg
    21301 aagtctatat tcttcagttg taaggcagtt aactcaccat atctcatacc agttaatgtc
    21361 agcacaagaa ccatatcagc gtacttttgg tgatattctc gacgattaag gacatcgaca
    21421 agtgctttta tttcttgcat ggtgagaaag ttgttacgct ttttttccag ttcttctaaa
    21481 gtctttggtt tttgaggaat cgtagtataa tcgacctcgt tgttttcaat gtaagagtat
    21541 tgaacagcgt aattaaagat acctctgagc ctatgccgta cttttttagc tgtaatatat
    21601 ccgttgcttt caataatttt ttcaatagcc tcttgaagaa aacgcctgtc aagattagca
    21661 agtatggtat cggatggtat gacttccttc atcttcttat caactgattt acaattatgt
    21721 tttgttgatt cctttactgt ttgcgcccat gatttataaa aaaggttata gatttcttca
    21781 aatgtaatgc tttctacttg ttttgtgcta agttttttat ttatcttctc ttgcaacaag
    21841 atagcagctt gatttcttgc ctggggagtt ttcttctcca tggtcactga aacttttttt
    21901 aatttctcgg tatacgggtc tttgtatcgt tcaaagaatt tgtattttcc gttgggaagt
    21961 tcttccatcc acattgcgtt tacctcactt ttttgttaaa atgggtataa gaaaaagagc
    22021 tttttaatgc tttttttctt accactagcc tcacgctctc ggtctgcaaa cttctgagcg
    22081 tggggctttt ttgagttgtt tccaaaatgg aaacagttgg tttttattct agacctgaac
    22141 taactttaga agtcaacaag aaagaaccgt cgtcttgttt tgaaaacgaa agaataacgc
    22201 tcttgtattt gctaccagta gaagtatatg atactgtctt actgtcgtgg tcatttactg
    22261 aactagttgt tacattgtta ggttctccgt gaacgctagc aacgtcatcg tagttagttc
    22321 caccagctcc atagttgata atatcaccaa cttgaagcgc atcaaactgt tcttttgtcc
    22381 agttaaattt agcatcttct tctttttgag atgattcgat agaagaactt acagagctaa
    22441 cagtctcttc aacgttttta cctagttctt tcaatgattt agcgtacatt gcttgagtta
    22501 ctaatacaat agcaatagat acgactgcta gaaccgtccc aataatagct agtgtttttg
    22561 gtctttttcg atttactgca aaaccaatta aaccgaagat aagagctaaa atagccaaaa
    22621 tgaatgaaaa attattgatg ataggcatcc atgagccaag tagagccagc gctccaaaaa
    22681 taatagctaa aatacctaaa actttgcgtt cttgtttcat aatgaaacct ctctatcagc
    22741 ttttagtgtg gatcagttgt tgcacatatt tttaatttac taatgataaa tactcttctt
    22801 taaccatgat ttcatttgtc atggttttta gattgtagta agacatgaat ttgaggtaat
    22861 caaactctgt ggggtcgtct aagctttcta gcgcgtcttt tacgagatga tggatcatat
    22921 ttctatcagc ttcgttttca cagcgtagtc gagcgttctg gtactctgag agtgtatggt
    22981 ctttgtgtcc aagttcgtgt agggcgactt ggatttgttg ttcaggagtc aagttgtggt
    23041 caatagcgag tacgtttgtg tctggattgt agaaaccgct actgtgccag tttgaaccgt
    23101 cgaagagaca aagttctact tgatattctt cgcagagttt agcgagtgtc atagttctcc
    23161 ttttaattag ccactcgata ataactttta atagctggat agctttttag ttggctttct
    23221 tgacgtttct ttttttgttc aaattgatga atggattcat tactgagccg tagcatgtaa
    23281 tcatattcac tgttattttc ttttggtcgt ttaacttgga cgtgattcat tttagattct
    23341 ccgtttttaa ttctataatt cctttgtgat ttctatttct atcaaaacca aattgtccca
    23401 tccagtatgt ttcattgtga gccatgtggg aatatatagg acgagttttt tcaatatgat
    23461 ctttatcgcc tatttgatag atgtctaagc aggtacttgc tttttcttta atatctttta
    23521 gatatttctc tatgtctgga gaatgtttaa aaaatagtaa gacatctatg tcttttgggt
    23581 tttctttctg ggtgcaaaag cttccgtcta gccatatacg cgtaatgata ttgctatcta
    23641 gattttttaa gaaagttgag agagcttgga aatttctagt tctggtagtg gagtttggga
    23701 agttatctac tagagttgat tgtatttgtg ctagtgagat atttgttagt attcctccat
    23761 ttaggttacc ttgatcattg aagtggagtt tagcgagtgt catagttctc ctttgttatt
    23821 tataaacctc tctgcggtgg gcgatgtcta cggctaagac gactagttta tcgtcttgga
    23881 tatcacagat gatgcgctaa tcgccaactc ggtatcggca gtaacctgat aggtttcctt
    23941 ttagtagttt agcgtgttga taggggttgc ttgtgttgtc tacgtttttt gtcatccacg
    24001 agatgatttt tcgtctagtt gctccatcga gttttttgag ttgtttttgt gctttgcttt
    24061 catagacgag tcggtacatt aggcgatgtc ctctctggtc attccaagac tttccaagag
    24121 ttcatctgtt gtatatgttt ttggattagg gtcggctaaa tactccatat aggcttggtc
    24181 ggctgctcgt gcgtcttcga tatcttccat gagtgccatg aagtcgtcaa aatccatggt
    24241 cgttgtgttg ataccgtgtt tgtttaggta gtccgtgatg taggaatttt tttctgtgaa
    24301 gttgatagtg atagtcatta gcgttctcct ttgcttttga agtgggcgga taggacggat
    24361 gtgatgaagt cgatatcatc ttcatttagt ggtttcccgt caaataacat ggtgttggct
    24421 gctgctttgc gtaagtctat gatttgtccg tttacttggg caaattcatc actcccagca
    24481 atagcagggt tatctgtacg acctagaaga taatcagtgg acacattgaa gtagtcagct
    24541 atttctgaaa ttcgttcagt agatggtttt gaacttttta aattataaat ggtatttcta
    24601 ctgtaaccaa gtttttcttc caatgaattt attgaaagtc cttgcttttt ggcaagttct
    24661 ttaattctgt caaatgtctg aaacattgat ttttcaacct ttctgagaac atgacaaaaa
    24721 atatttaata tttctcatta aaacacttga caaagttaat gcgaagtatt aaaatagttt
    24781 ttgtaagtta atgagttagt aaaaaacgaa gttaaaactt atctaaaaat aaatagcttt
    24841 ggcgagcaag aaaattgata gatataaggt tttatcaagg tttttaatta tgctttcatt
    24901 ttaatactat acattaattt tgtcaagcat tttataaaac aatttactaa ctttttttct
    24961 tacttttaaa gaaaggaggg aggcagatgc caaacatgga tggtggacgt caaaaaatca
    25021 gagattatct gaaagagcac aacttgacga tggcgacgct agcagtacag tatagcatgg
    25081 ctcgtcagga tgtgacgaat atcctgaatg gaaagctaaa aaatccacaa gcgaatcagt
    25141 tcatcgctcg tgtgattgaa gattttaaaa ttcggtaaaa atattggttt aagtaggagg
    25201 aaagatggaa gaagacatca gagttcacat gccttacgag gtatttaaaa acctgcttgt
    25261 tagagcaggc agaataaagc gtgaagaagg caagcagata acttggacaa ataataccgc
    25321 tccgtttaca aaagagcaac ggagggaaat agatgaactc tacgagcagt tcgcagaaga
    25381 ttgaatgtgg agtttgtcat tgatatgttt gttagcaatc aataaacatt cattaagcct
    25441 atcaaaaata tatctgggtt cttcgattgt gtctgggtca taggactgtt cttcaaattg
    25501 cacatcccaa atataaagcc catcggggtg gggatatcca gcttgataac gtagcacatt
    25561 tctaaaatag atgaattttt tttgctcttc atcgctatct aaaaatagat aggtcttata
    25621 aaagatatca tcgaagtttg tgatgatatc taaatcaatc ggaggagcat cgtcaagtct
    25681 tgattctacg tatgagacgg ttttaccact aatcgatgca aaattttgaa aagttgaaat
    25741 atataaatct ctatcctgac ttagttgggt atttaagaaa tcaaccttct tttcttcgag
    25801 tttattttta ttttcaatct ttttttgctg gtaagcaaaa ccgtgaataa tcaaatttgt
    25861 taaaacagtt gcaccaacag aaatcaatgt tgttgtaaat acttcagaca tacaaatacc
    25921 tcagataata tttttaaatc attatatcac aaacagaaag gagtaggatg gaagaattta
    25981 ttgatgctct tgaaaaagaa aaagaccacc ttgaaaaaat cattgaggta gtcagctctg
    26041 gtggtaaatt tctgagattg ccgtatcaaa aaagtcacgc tcgattagtg agaatctgaa
    26101 attgatttct caaaatcttg atagactgag ctgtttatat aaccaaagag gagaaagaat
    26161 gacagacaga gaactattta agttaccaga agattatgta gaatctactg gacttgacaa
    26221 gattacattt gaagtacctt ttgaattgtt tacgaaaatt ctaaaagggt acggacataa
    26281 gttagcgtgg gaggatttcc gacaaataaa aatccaccca agcactagaa caaaaaagac
    26341 ggttggacag tgtcagtttt tgtttagtat ttggatgaat gatcatttga agccagcgat
    26401 taaaccttca aaagagttgc agaaagaacc tgtgcgtaag acaaagaaac agaaacgtct
    26461 tcataagtta gcacaaaatc ttcttcatcg catgaagggt tgaaatcgcc aatgtatgca
    26521 ccttgctctg ttttgcagat tagaagagta ccatcttcgt ttgtaactgc atctagataa
    26581 ggtcccaaat cagacttagt cataagttat cctcctttct gcttatatta tagcagaaat
    26641 agaggttaga aatagaaagg agtaggaaga tgagaccaaa acgatatccg tatagtggga
    26701 aaaaagagtc cacctttgta aaggcagacc ctgagttagt tgaaaaactt ttaagaaaca
    26761 ctagttttct tgagtgttta caaaaaaagc ctatcaattt tcagatagac tcagaagaat
    26821 ttaagcgtct tagctataaa gccattcatg atacttctca agtaactcaa taggaggaag
    26881 gaataaaatg attcaccatt atataactca ctatgccagc aatgggaaag attacgccga
    26941 agcatggatt caaattgatt ttttgggaat gtgcttttgt gtatggaaaa agcgtacaac
    27001 cattgaacga ttgtacgcaa acgaagatta gacttttttc caaccgttgc ctttagcaga
    27061 tgtcggaggg agccgatcac cttttccgat agttgcggta tgaccattag taacttttcc
    27121 gccacgaggt cctacctcta catagcgacc aggtttctga ttatctgttc caggttttat
    27181 tggagtattt gccatactat ctcctccttt ctattggaat tttgactaaa acggtgagag
    27241 gtcctagtca agagtattat agcaatttag gaggatatta catcagtctt gaggctgata
    27301 taggaggttg aatggaagat aaaattatcg aacttgctga ttacttcatc agcgaatcta
    27361 caacgtacag agaagctaaa atagcgtgtg agaagctatt gaaacaagtc agccatgaga
    27421 tagaactcag ggcgatggaa agtaggacag tatgaaagaa gcagtaaagg aatttctaaa
    27481 attcaggagc cgatttacaa aaatagaatg gtttgaaatt aaccaagcta tcgaagctcg
    27541 tttaaatcaa aaagccgacc agttgaaact ggacgactta gatttagaaa tcatttctag
    27601 cagactagaa aaagttatct agaaacgatt tgaatgaaca ttggatggat acgatagtca
    27661 gcgccacgat agtgaatgta gatataatcc tgatggtaca tcgagtttgc ttcaggttta
    27721 gaaattggtg agtagagttc tgcattttct tcccaccaaa tgtaaggatt agccatattt
    27781 ggtcccatta cacaatcgtc gtcggctgat aggttcaccc aatttccgca aagacatgcg
    27841 tgaatttcag tcataatatt acctcctttc tggtttcatt atagcagaaa aggagatagc
    27901 aaaaaagcac ctgacggcaa tcaggcgcat gacaaaatta ttcaagaaaa ttataacacg
    27961 aaaggagcaa aaatggaagt agttgaaatt gtaagaatta aagatgtgat cattgaaaaa
    28021 gtctctgcta atgatgaaga gttaaaacgt atctttggat gttcaaaacg acaagcagga
    28081 gagcgaagaa gagaaatgca aaaactccct agtcagcaaa aacatctttt ggatagtgga
    28141 caacttgtaa cgattaaagg tttctatgaa tacttgcaat atcgtggaac taaagcttgg
    28201 aaaaaagaaa tggaaacaag aaagaaaatg aggtcagcag gatgaaccta ctatcaagaa
    28261 tcaaaaacta tttttcggaa gaggtcaaag aaactaatct cgactggaaa gaggtcgctt
    28321 tagacctcaa tcaatcacta attgaaacac aggaaaaact tcaagaagcg aatcaagaaa
    28381 tcgcagactt gaagaaaatc gtagcaatct acaaagaaaa ggagaaagaa aaatgatgga
    28441 atacatttac ctggtaataa tcgtaggaat tggactatgg tcgctagtaa ataaactaga
    28501 tgaccacgct gaaatgaaac aaaaagagcg ccagctgatg gcaaacaatg tcgcacggat
    28561 gaatctgaga aattcagata agcaatttac ttatgatgta gaaccgcctg aagggttgaa
    28621 ataaggagga gaaacatgac tcaagcggaa caaattaggg aatattatag agagcaccct
    28681 gctgcctcat gtgatgaagt ggctgaggtt gtcggtacaa caaaaagcaa cgtaagtgca
    28741 aacctggcca aagacatcaa ggcaggcaga tgcgttcgct tggaagacaa gtcatacgac
    28801 tactcccctt actttaatca cacacaagcg ctcactgagt tggttgattg gaagaatgat
    28861 accagacgtg agtgggtgga tatgctgaca agagcagcag aaaaagaaac ggatagcaat
    28921 gttatgcgtt tgttaatcaa agaagcaaat aaattgatga aagaggtgac gaagtaaatg
    28981 gttcgaaata aattgacaga tttaacaaat actttgtttg ctcaattgga aaccttggac
    29041 gatagggatc ttactgcaga tgaattaaag acggaactcc aacgttcaaa acagatggtc
    29101 gcaatctcag gtcaaatctt acaagcaggt caattggcgc tagatgctga aaaattcaaa
    29161 gacaaggtag gtgaagtcaa tgccccgatc gctttgctgg aaggatgagt atacagagta
    29221 catgcatgag atatgccctg gccgattaac tcctgaagta accaggttac taaatgagaa
    29281 atttggtacg acctatacca agactcaaat aggagaagta cgcagacgtt tagggttacc
    29341 tgttggaaaa gtatatcaag gtaaattgtt gacaaaagaa caacatgatt accttgtgtc
    29401 aatccaaaaa aataagattt ctcgcgatgt cgcaaatgaa atgaacctaa aatttggatt
    29461 atcactgact gagaaacaga ttaagagtta tcgaagaaat aataatctac atagtggttt
    29521 gacaggaaga ttcgagaaag gtcagactcc tcacaataag gggaagaagt accccaatat
    29581 gccaaaaaac agcgggcagt tcaaaaaagg taatcgacct ccgaattatg tacctgtcgg
    29641 tactatcaac tacacaacaa acggttatcc aaaagaaaag attggagaac ctaatcaatg
    29701 ggttttgaaa caccgcaagg tttgggagga ccatcacggg ctgataccaa aagggtactc
    29761 aatcgttttt ctggacggtg ataaaacaaa ctatgatatt tcaaatctgg catgtttatc
    29821 taagaacgaa attgctagaa tgaatcaaaa tcatttattc acgtccaacg ctgatttgac
    29881 taaaacaggt attggactaa caaaacttac aaataaaatc agagaggtag aaaaaaatgg
    29941 ctagtttata cgaactaaca ggtcagttcc tgacaattta ccaattggat atcgatgacg
    30001 aaacaaaaac ggacacactt gaggccatcg attggcaaga acaatttgaa cagaaagcag
    30061 aaggatatgc ccatgttatc aagaatctag aagccgacgt ggccatgtac aaagctgagg
    30121 aagagagctt caaagccaag aaacaggtgg cacagaaaaa gctggattat gtaaaggata
    30181 acattatggc agctatgaat atcacggggc aaaccgaagt taagagtggt gccctgatta
    30241 taaaaattgc taagaatcca gaatcagtca aggtcaacga agacgacctt ccgaaaaaat
    30301 attttacaaa aaaagtgacg cttgcgccgg acaaaaaaac actcaaagag ttgcttaaat
    30361 ctggcaagaa agtcaaaggt gcgaaacttg tccggacaga aaagttggtg attaagtaat
    30421 ggaattgatg aataaaacac gagtaacaga ttcactagca gttgtgattg gactagaatc
    30481 gattgaagta cttgttactg aaggttttct atttgatgtt gcgattcgtt ttgtaaaagt
    30541 agacgaaaca aatcttgatc aaggaaatga aaagccagta ttcactccgg aatgcaagct
    30601 ggtcacagtt gctaaataca aggaaaaacc tatctttgaa tcggaggaag atattcgaaa
    30661 atttgagaag caagcaaaag aagttaaatc gctatttgcc tttgcaaagg taaataaaca
    30721 aaattggttt aacactgccc tttatccagg agtgctgact gagaaagttg gtgtttgatg
    30781 aaaattttag ctattgatcc aagcagtaat aaaattgaaa ccagcacaac aggagttgtc
    30841 ttgttggata atgcaagatt agttgatagc tgggttgtct cttatggtat gagaggtttc
    30901 gctgattggt ttcacgaaat cggaacaaat cttgaattcg atgtagttat tgttgaagaa
    30961 tttaaggcga gggataacga caagtcgaaa gataatagcg tggcagaaac catcgcctat
    31021 atccaacttt gctatccagg tgccattctt caattcaatg caggttacaa gtcggatatt
    31081 ccaaacgatc ttttgaaaat cttagacctt tggaaatttg aaaaaagtca tcatcaagat
    31141 attcgagcag cagcaagact tggattattt tgggcaatga gaaatgatat tgaagaagtg
    31201 gttcatgata tcggaaaggt ggtgagtgag tatcacaata acgctaagaa agtggcaagc
    31261 tgaagcgatt aaaagaagtg aacatttatc taatggaatc tttttagagg ctcttggggg
    31321 cagaggcaaa actatctgtg cacttgctat tgcaaaacat aaaaaagcta aaaaaatcat
    31381 catcacaaac aatcgactag ctattctgaa tggttggata gatgcagtca agtttatgaa
    31441 ttttgataaa ggtgttgaga ttatcattca gacagataga tatcttcaaa atcaagtcaa
    31501 aaaggggcat aaattagatt gtgatgtgct gatagtagac gaatggcaga atatgtcttc
    31561 tgacaaacaa gtggccttat atcgcaaaat aaagcgaaaa tacacgatag gtctttcagc
    31621 gacaccaatt cggaaaaaag gacaaaattt ctatccgctt gaaaaaacgg tatttggttg
    31681 ggcaacccca aataataaat ttgactggca aaagactcat gggaaaatgg tctatgatcc
    31741 atttagctat tcaaaagaga agtgggaaga ttttcaaaat tatgaaagtt atatctcgag
    31801 cttgcctaat ttcttccgct gggaagagat tgaaggaatt gagaatgcag ttgagaataa
    31861 cggttttgag attaagtttt accgaaagag agtcgcctct ggcaatccag aaaaacttgc
    31921 agaatttaga aaactaaatc ttgtaacagt ggacggcaaa actgcaatgg ccaagcaatc
    31981 gtttggaaga aagacctttg aacgctacct taatcaaaca ggcgtagcag tcgattttcc
    32041 aaaattaaag ccagtaaatg cggatacgcc attgatgtta caacttgacg gtttaatcga
    32101 acgagcacca cacgatatgt tgattgtcag taaatctaag cagattgtca acgtcattag
    32161 cgagcgccat cctgaaattg gaatctggac gggcgatatt caagaaggac tttataagaa
    32221 atccgtggtt gctactagtc aagtgttagg tgtcggagta gacggcttgc aacacaaata
    32281 ccaaactatt gtcgtattgg atccagtaga agaaggttct ggagaatatg atgattatcg
    32341 acaattgctc tggcgcataa caggaagtcg tcagcagcat gatgtaaatg taattgaatt
    32401 ttattataaa gaaagttaaa aaaagaggaa aacaaaatga ataaaacaac tgaaatgatc
    32461 gtatttcgta gccgtaaaac tggagaattt cttaattctt acaaggacag aagttcttta
    32521 gcatttgcag ctgacttttg cagcttggaa tattgtttga agcttcctcg taaaaaatac
    32581 gaagacaaca aaaagactta caaggctctt gctgcagctt ttgactgtga aattgtcgca
    32641 gttgaagcgg aatacaaatt gacctatccg aatggatcag aagttgaacc tatcaagcgt
    32701 gaccgttcat caattgagga catgattaag gatattattg gaggggttct ctaatggcat
    32761 ttacacttcc agcaaataaa ccacaagttc ctaaagatac cccagaaatt ttttcatcta
    32821 cggcgaaacc atgagcggaa agtcttatct tgcaaatgaa ttcccaaatc caatcgtttt
    32881 gaacacagac gggaatgcag aagctaacac tgttccaagc attcagctga tcaatgaaaa
    32941 agatgacaag ggacgaatta ccaattcagt aattaagcag cttggagata tcttgcttgc
    33001 tctccagaca cagaagcact cttatgaaac agtcgttatt gatgtaattg acgatgttat
    33061 tgaaatgatt aagattgcag tttgtgatga attaacccca gttggtaaac ctcgcttgaa
    33121 atccttgtcg gaaattccat acggcaaagg atacgacttc tttaaccaag ctatcacaga
    33181 attagtcatt gacctcaaag cattgccaat gaatgttatt tacatcagcc gtcaggtatc
    33241 tgaatatgat gacaatggca atgccaccaa agacaagcca agcttgaaag ataagtatgt
    33301 caatcttatc aatggaaact ctgatttgat gatccacact gaaaaactcg gcaacaacta
    33361 caaccgtgag gttgaccgca agcgtaagac ctattatgcg gaccaggttg atgacaaggc
    33421 catcttgaaa atcttggcaa ctatccgtgg ggctgttgag cctgcaaagg gcaagctagc
    33481 tcctaaaaaa gaagcagcta agacaactaa accagctaag atcgaaaaaa caaaagaggc
    33541 acctaagaaa gaagttgact ctgatgatga actattttaa gaaataaagg agaatacaca
    33601 tgagcttact agatatcgca aaatcaatca aaaaagaggg ctttgaccca cgcaaagaca
    33661 gcgccaacgg tcctgcacca atcccagctg gtacttatcc agtagtcctg aagaaagcaa
    33721 ccttcaacgt atcggacaaa ggctgggaaa gccttggtta tcaatttgaa atccgtggcg
    33781 gtgattacag tggacgctct gaatttgcaa catttggcac actgactgaa tggaacggta
    33841 agaaccttga ctgggcagtt gaacgcacta tgaaattctt tatcaaagcc ttggtccttg
    33901 ctggcgacag tatgcaagga aatgaagaag acggtaaagc cttggaagag gctctacaac
    33961 gtaaggcagt tggctcttac tacaaccttg ttatctctgt gactaagggg aaagatggcc
    34021 gtgagttccg aaactatgac cttgaagaag aagaagcaca accgctgact gaagctgata
    34081 tcgatgaaga tgacctccct ttctaaaaaa tagcaagttt tgggtcattg atgaaactga
    34141 tgaaagatta ggaccattca atacatttga agaggcttat caatcgttgt tattttattt
    34201 aaaaatgact gaagatgaat atcagtcaaa ctatacggcc caggaacttg tttatattta
    34261 caaagaggag aaaaaaccat gccgtcgatg aaagaatacg cattacagta ccaaaagtta
    34321 gggttctcag tcattccaat caatcctaaa aacaagatgc ctttaatcga atttgctgat
    34381 aaaccagcca tgactgcaag tgaaatcgaa cgattttggg atggataccc aaatgcgaat
    34441 attgctttaa ggacaactaa cttctttgtc attgatatcg ataagcatgg caaagagaat
    34501 ggctttgagt cgttaaaaaa atgggaacat ttaaatttaa ttgaaccaac tcttcaagcc
    34561 aaaactgcta gtggtggaaa gcatctgtta tatttcaaaa gagatgatga accaattact
    34621 cagatgatta aattcttgcc tggtgttgat atcaaagcgc acgagaataa ctatatcata
    34681 gtagcacctt cagcaacaga gaatggccag tatgagtggg atttggagaa atcagcggaa
    34741 ggtgggacaa tcgtaactcc ttcccgtgat ctaatccgag caattaagaa gcagtatggt
    34801 aaaactcatg gctatagata cgatggcaaa gatggtctta gggatttagc gaggcgttca
    34861 caaaccagag accgaacaca gactacagat ctctttgaaa ccatcgccct tggttttggt
    34921 gatgaaggtg gacgaaatga caaactagca aaattcgtag gtggtctctt atatcgtgcg
    34981 gtcgacgatg gtgtagttgt tcaacttgca agattagcaa atgcaaatag tccaaaccct
    35041 ttgcctgaaa aggaaatgat gcgtactatt gaaagtatga ttaaaaaaga taggaggtga
    35101 ttgtgattgg taatgtagta agtattgact cacaacctaa gatgataacg actgccaagg
    35161 gagacatcaa ggccaacagt ccaagtaatg tgttgatgtc tttcaaagct gatgatcagt
    35221 tgagtattta cctaaagcac aacgattttt cccaagagca tgaactcctt aaagatatca
    35281 agatcggcaa cactcttttt aaaaaaggtg agctcccttc taactttgat tcagtcgtaa
    35341 aagtttactt tgaaagtgtg ttaggtgttg ctttctcaaa ccaagcgatg cttgatggca
    35401 tggagacttt cttttcagaa agatcataca atccagttat tgagtatatg gagagagcaa
    35461 ctgaaaagtg ggacggcaga aaccggattg accgcatgct tcaagtatat ctcggcgctg
    35521 aagatatccc tttagtttct aaaatcgctc aaatgtggct agttggtgca gttgctaaag
    35581 tttatgatcc atacgttaag tttgactatg ttctggacct ggtcggtgga caaggagttg
    35641 ggaaaacgtc cctccttcaa aaattgggtg gcgaatggta tacggatgcc gtaacagatt
    35701 tctctaataa agataattac gacattatgt taaagagtct aatcgtcaac gatgatgaaa
    35761 tggtggccag taatcggatg agctttgcag aaactaaggc ctttatttct aaaactagcc
    35821 tacgttatcg taaaccatac atgaaacgaa cagaagaatt tgccaagaac ttcatcttag
    35881 ccaggactac taatcaaaaa gaatacctca aggacaaaac cggtgaacgt cgttttctac
    35941 cagttatggc agatagtaaa cggcaaaaaa aacatccaat ggaaatcgag ccagagacaa
    36001 ttgaacaaat ctggggcgaa gccgttacaa tctatcgtgc tggtgctgat ttgatgtttg
    36061 atgaaaatac agaggatgaa ctgaatatct accgtgaaca gttcatgtat cgtgatgaag
    36121 ttgaattaca agtgcttgaa tatcttgata tgcccgtccc tgaaaattgg caaaactggt
    36181 ctattcagca acaacatcaa tacacaagta aatatttcga taatagtagc gactttgatc
    36241 ctggaagcaa aaaactagat aaggtctcaa ctcgtgaaat gatgtacaac ttatttatga
    36301 gaaattcgaa tgacaggaag ctgtcaacga agattaacat gatcatggat aatcatcctg
    36361 attggaaaaa aagtgttttc cgggcaggag gtaaaagtac aaaagggttc gtaagagtga
    36421 aagattcgga aaaaaactaa tcggtagcaa ttaaaaaatt atcggtagtc atcggtagca
    36481 gttgaggggg agatcggtag cattctaccg ataaaatagg acatcggtag cacatcggta
    36541 gcagtctaac cccttgatat tactgacttt tatttaatat ttatatataa tgctactctt
    36601 ctatctatat ttttaaaaaa agtatataaa ataatagtaa taataaagaa agcctataaa
    36661 atagggattc ttgaaaaaaa ctttttactt tttagaattt atcggtagca cggtagcagt
    36721 ttagaaaaaa gaggtaaaaa tgtcatacac agtaacatta ttttttgaca acatggtaga
    36781 cgaaactcac ttttttaaga aagagagtga tgctgccaaa tgcaaggcgc agttagaaag
    36841 caagtatcga gggaatcgaa tgtataaagt taagcaggag aaattggaag aatgaataag
    36901 caggaattga ttgagaaata taaagagctg gagaatagtt catttgatat tgcagcgatt
    36961 gtagtttgtc agctaatttt aaaagacttg gaacagctag atgaaccaaa accggtcaaa
    37021 gttcagcagt ttgtggcgga ttttatcgca gaacagaaaa aactgggtca tacactgtcc
    37081 tactcaatag acgcaagcat gtctgatata gttgcagaat ggtattggga taattccgaa
    37141 ctcttcgcac tagcttggat tttcggctac gaggtcgagg aagagaagcg gtatacagta
    37201 gtgacgaaag caacaaaaca accgctatat tataatgcta tggataagaa actattcttc
    37261 tctatgggcg gactagctac aaaatttact cgcaaacaac tcaaagaagc ggacttaggc
    37321 tgggttttcg attgtgaagg aattgagatt gaggaggtgg agtgatggaa gatgagcaaa
    37381 atattttaga gacacaattg attttaggta agcaagtttt agaaattgta ttggatttgc
    37441 taaaagacga ttcaaaaata ggggtagttc tacctttaaa cataaatgac cgtgaattta
    37501 caattactgt agaaaaggag gtcacagatc gtgactaagg ggtgtttgtg gttatgaagg
    37561 acgtgtatga caaggtgaaa gtcggggatg aggtgatgtt gtgaaattct tgaatttatt
    37621 cgcaggaatt ggcggttttc gtttaggaat ggagtctgcc gggcatgaat gtataggatt
    37681 ttgtgaaata gacaaattcg ctagagctag ttataaagct atacacgata cgaaaggaga
    37741 aattgaatta catgacatca caacagtatc agatgacact attcgaggaa tcggaagtgt
    37801 ggacattatc tgtggaggat ttccgtgcca agctttctca attgcaggaa acagacgagg
    37861 ttttgaagat acacgaggaa ctttgttctt tgaaattgct aggttcgcat ctattctcag
    37921 acctaaatat ctattccttg agaatgttaa aggattgctc aatcacgaaa atggagttac
    37981 attcgagacc attatctcaa ccttggatga actggggtac aacgtggaat ggcaagtgct
    38041 taacagcaag aatttcggag tcccccaaaa tcgggaacga gtgtttatta tcggacatct
    38101 tagaagagaa cgtaccagaa gaatttttcc tctcagcgga aaaaatcagt caactagtaa
    38161 ccaatcagtc atgaaaattg ggaatataaa cccatctggc aacggaatga atggggaagt
    38221 ctatcaagct gatggtctag ctcccacgct aacaacaaac aagggagagg ggcaaaagat
    38281 agctataaat agctatcacg aaaacaatca tttatcagat ggctttcgaa tcagaaagct
    38341 aacacctaaa gaatgctgga ggttacaagg ttttcctgat tggacttttg ataaggcgca
    38401 ggaggtcaac tctaacagtc aattatataa acaagcagga aatagcgtga cagttaatgt
    38461 catagcagca atagcaaagg agttatcatg aacgcactag aaaaagtcga acaatggttt
    38521 atcgaccgtg aaatcaaaga tcgaaaaggt cgttggattg atggtgcttt cgtcaaagag
    38581 gaggatttgg tatgataccg aaatttagag tgtgggtaaa aataggaaaa cgtatggttt
    38641 tttcagatga cattcttgct attgactacg aaaacaaaga aatagtgaca caacaagtct
    38701 atttcgagag tggtctagca gttgaaagag atatctattg ttatgatttt gacgatatcg
    38761 aactcatgca atcaacagga cttaaggaca agaacgggaa agaggtcttt gtcggagata
    38821 ttataaaatg tacaagagga tgtctccatg aagtatattt agaaaaagaa tacggtggca
    38881 cattcatagg cggaatgcct tccatatatc taaagggatt gctaaatggg tatgcgtgga
    38941 ctgaagacga ggaaatcatc gacaatgtct acgaaaaccc tgaacttttg gaggtaactc
    39001 atgaataaac gtcaacgcaa aaagaaaatt ttgaacggtc tgaacaaaga agaaagatac
    39061 cacaggacgc attgtcctgt ctgcgatagc gaagctggtt tattcgacag atattttaat
    39121 acgtacggtt tctgctctga atattgtggt tatgaatact atggaatttc aagattataa
    39181 aataaaggat tgaggttaaa atgacattat ttgatgaaat gcagcaatta agctcagaaa
    39241 gccacgcaaa atggttcgag cgatattttg agaaatataa cctagaacaa aaactaaaaa
    39301 cttctgctca aaaaggttat acaggttatt taatcaatgt ttggtcagtt agagacgaat
    39361 atctcaggaa tcgattagga gatgaaagaa cgttggaagc gttaagagaa ttattaggag
    39421 ctggctttac tgtcaaatat aagctttatc tatctaaaaa tattttcact ggacaagatt
    39481 tcgtttctaa caagaaaatt cacattactt ggtaaaacaa aaaagccaag acactctctg
    39541 tctcagcaat aatctcaata atattattat atcacaaagg agacagagag tgaacaaggc
    39601 taaagaacta ttgaaagagt tgcagaatct ggacatggac attcaaagcc gtatagatga
    39661 aattaacgag cttgaggcag gtttgctctc aagtcctaag tggtcagatg tcaaagttca
    39721 aggtggtcaa gctagaaaag ttgatgatgt ctatactcag cttgtcgtga tgaaagaggc
    39781 tatagaacag gatactaaag aggttatcaa cagaaagctc caactaggta ggatgatcaa
    39841 taggcttaaa aatccaaaac atagaactat tttgagaatg acttacatca ataagatgta
    39901 cgttgatgac atctgtgaca gcatgagggg cataagttct cctacttact atcgtttgaa
    39961 gaaacaggca gtaaaggagc ttgatattat tctttcagaa ttgatagtaa atgatagtaa
    40021 ctgtacaggc atgaagtcta aaatctgtta aaatggtagt atcaagaatt gaaaagagag
    40081 gtctcagaat tggtagatgg ttacctgtaa tgtcaggggg ctgtaatggc cttggaggtt
    40141 caaaccctcc cctctccttt gagtgtttgt gtcccagaat ggggtaggca acaggcttag
    40201 cattcatata tcactcatta acttacaaat ggttgcggag cgactggacc ttgcatgatt
    40261 gcgtagctaa ttatattccg gataagttat aagctagagg gtttgattcc ctcagaggtt
    40321 ttaaatgact acaaaaaata aaaaaagaag tcaaaattta atacgcacgc aaggttgtag
    40381 tcgccttgca cttttagggc ttagcctaga taatctgtgg taactcagga aaaggatgtt
    40441 tttaaatcta tcaaacatcc tgccagcaat ggtcaatcta agcaatgtaa tcttaactat
    40501 ttcagttttg gaataggtgg gcgaagttaa agcagaaaga ttccaacggc aaggtgctga
    40561 ggaaatgcaa acgtggcagt ttggctgtga aacgagtcta taagaggaaa gaggtatttg
    40621 gttcgaggtg caacaagagc ttaataccat atcttacaaa aattgggcgc ctcccaaaag
    40681 tatgtaaggt gagttgattg tccgcaaaac aatcgataac aagcaggcgc tgtgcatttt
    40741 gttcttcaaa agaggatgaa acacatggcg atgcgtgtct gtgatagatg aaagatgatt
    40801 tttatatttt aaggctattc aagatagaaa aaaattcgaa aaaagcaaaa gtcatcgccc
    40861 gtcgcaaacg aaagtgtact tcggcaatta gattgcctgc tcaagtctcg caaggataag
    40921 agtaaagtca aagagtaaag cagcttagac ttttagcggg gtcttcgtta attgaaaaat
    40981 ggcttagtag tttgtgatgt aagaagtgat tggtctaacc aatcgtgcat gagtgataca
    41041 agtaggaata tttgtggaca agataataaa ctataagtta tcaaaagtca ctcgtttaaa
    41101 gcagtagtct catgctagtt aatggataca tggtagacgg attaagtcct gtttagggaa
    41161 ttgaaacgta ggcaggttcg aatcctgtcg ttccaattgc gattttaatt cgcagagaga
    41221 ggtcttgaaa aggtcgcaca tcgtgtggct tttttgattg tttgaaaggt ggtgatggaa
    41281 aattgagtgg attgagaata aaacaaaaga gatttgcaga tgagtacatc atctcaggta
    41341 atgcgacgga agcctataag aaagcaggtt atcgtgtttc tagtgataga gtggcaggcg
    41401 ttgaaggaca taagttacta aagaatccta agattaaaag ttatatagat gaacagttga
    41461 aacagcttga ttctgaaaaa atcgcagacc agcaagaagt ccttagttat ctaacctcgg
    41521 taatgcgagg agagacacaa gaacagactt tgataagcat cggagaattg ggtcaaacga
    41581 ttacggatat taatgttgga gcaaaagaca gaatcaaggc agccgaacta ttaggaaaac
    41641 gtcataggct ttggacagac aaagtagagg cagacgtttc tgggacggtg gtgtttgcaa
    41701 atgagtcaga cataccagat taaacaaagt gatattgtaa tcgacctacc taagacagta
    41761 ggagctggat acggacagtt ctggcgctca agaaatcttt atcgtgttgt aaaaggttcc
    41821 cgtggttcga agaagtccaa gacaaccgct ttgaattatg ttgtccgtct tttgaaatat
    41881 ccctgggcca acttgcttgt tattcgtaga tactcgaata ccaacaagca atcaacttat
    41941 acggatttta aatgggcgtg taatgtgttg ggtgtgactc atttgtttaa attcaatgaa
    42001 tctttgcctg aaataaccat aaaagcgact ggtcaaaaaa tcctattccg tggtttggat
    42061 gatgaactca aaatcacatc tatcacggtc gatgtcggca gtctttgttg ggcatggttt
    42121 gaggaagcat atcaaattga gactgaagac aagttcagta cagtagttga gtcaatccgt
    42181 ggtagcctgg atgtacctga tttctttaaa caaatcacag tcacatttaa cccgtggaat
    42241 gagaggcact ggatcaaacg tgtgttcttt gatgaagaga ctagccgagc tgatacattc
    42301 gctactacaa ctacttatcg atgcaatgaa tggctggatg aagtcgatat caaacgctat
    42361 gaggatttgt atcatacgaa ccccagacgt gcgagaatcg tttgtgatgg cgaatgggga
    42421 gttgctgaag gtttaatcta tgagaacgtg accgtcaagg atttcgataa ggatgaattg
    42481 ctacgagatt tagctaataa gttatgtatc ggtcttgact ttggttttac tcatgatcca
    42541 actgctttgt gttgttcgtt gataaatgac acgacgaaag agatttatgt ctttgatgag
    42601 gcgtacaagg tcggtcttat aaccaaagaa gttgctaaga tgataaagga caaaggttat
    42661 catcgctcac aaatcattgc tgatagcgct gaattacgac tgattgagga attaaggtca
    42721 gaacatggta taactcgaat taaagagagt cggaaaggta aggatagtat tatggcaggc
    42781 gtatccaaat tgcaaggata cgctatttat gtgcatccag attgtaaaaa catcatggat
    42841 gaattttata gttactgcta ccagcgagat aaagaaggca actggttgaa taaaccagag
    42901 gataaaaaca accacttgat ggacgctttg cgttacagcc ttcaatgtat cgaaggtgga
    42961 aaagcaaccg tccgcagacg ttctgattat ggtctataga gaggaaagac atgtaccaat
    43021 atttaaccta tccacgggat ggatatgatg agggttcttt gaagaaagac ctgatttaca
    43081 aattgataac gatacgtaac actgaaagct cacatttgaa gaagcttaaa agctactact
    43141 tgggtaagca tgctatctta aaacacacga gacgcaacgt gaacgcaccc aattaccaga
    43201 cggtagctaa tcatgccaag gatatcgcag acatggctac gggctatttt atgggcaatc
    43261 ctatcaagta taacaatact gctgacggtg atatcgatga actacttaca gcctttgatg
    43321 gtgctgagat tgaccaagta gatgctcaga atgctttgaa catggctatc tatggtcgtg
    43381 cttacgagta catctatgct aaagagggtt tgactgagtt ggattcaact agtattgatc
    43441 cagaaaatac cttcatggtc tacgatgata gtattgagcg gaagcctttg tttgcggtct
    43501 attactatga agtaaaagac gatacgaaag acactaccaa gtaccaggct gaggtcttta
    43561 cagaaaatct gcactatcac atggtgctga gaagtacaga ttcaggaaca actcagagcg
    43621 aggaggcaac acctcacaac cttggtcaaa tcccaattat cgagtatcgc aacaatcact
    43681 ttgcgattgg cgactacgag caacagatta gcttgataga cgcttataat tccttgatgg
    43741 gtaatcgtgt caatgacaag gagcaggcag tagagtctat ccttgtctta tatggcacac
    43801 agttagcaga cactccagaa gatgccaagg tagcgatgaa gattctttct gaagaaggtc
    43861 ttttggaatt gccgggcgat agtgcaagag ccgagttctt gaagaatacg ctggatgaaa
    43921 gtgctacaga aatcttgcgc acagctctga aagaggatat ctacacattc agccatgtgc
    43981 ctaacttgac tgatgagaac ttcgcaggga atacatcagg cgtagccatg gaatttaagc
    44041 tgatgagcct tgaaatgatt accaagacca aggaagcgaa ctataagcgt ggattaagac
    44101 aacgtattgc gatttttgct cattacttgg gtatgaagca gattgcttta gagtctcatt
    44161 caatcgttcc acaattcagc cgtggtttgc ctaaaaactt gctggaaatc tctcagattg
    44221 tgaacaattt ggaaggtaaa gtgaccaata ggcagcttat ttctctcttg ccgtttgtgg
    44281 aagaccctga tgctgaattg gaagccttgg aagaagagaa aaagaagaac atggaagaca
    44341 tgccgatgtt taaccaagac aacacgaaac ccgaagacga ggtagaggat gaagaatcag
    44401 gagtattggg cgaagaggaa agccaatctg atttaccaac agatggacaa ggccgaaaag
    44461 caggcagacc agttcgataa ggtctatcag gaagccaaga cttacttgga taaggaagtc
    44521 aataagattt tcgataaatt ccaacgtgat tatggtctaa gtcaggtaga cgctagacaa
    44581 gtcttgaaga acatgaaagc caagaaagac ttgaatgaac ttcgtaaggt gcttgaagca
    44641 agaccgaatg atccaaatat ccaaagacta ctagctgact tagacagtcc ggcttattct
    44701 ttccgtatga agcgtctaga acgtttgagc gatgatttag accgtatgcg tgaatctatc
    44761 tatcattcgg agaagacagg ctcagatgcc ttttatagcg acctgatgaa ggatagttac
    44821 tacaaggcta ccttttgacc tacaacagca gacaggacta gcatatggct tttctgggct
    44881 tcctgagagc gagattaaac atctacagtc tttcagttgg gtaggtgacg gaagtacgta
    44941 ctcaacaaac atctggaaga atacagggaa gcttacatca agcataaaag atgaattact
    45001 cataagcctt atgacaggcc gagatacacg agaaactgca caagcaattg ctgagcggtt
    45061 caatgtgggg cagaacgatg caaggcgttt ggttcggaca gaatcagcct tttttcataa
    45121 ccaaatggag ctactcaact atgaggaagc ggatatagag aagtatatct ttgtggccgt
    45181 cttagacaag cgtacatcac gcatttgtca ggagcatgac aatcaggtct atgataggga
    45241 taaggctgtc cctggtgtca attgtccgcc tatgcaccct tggtgtaggt ctactactgt
    45301 cggatacgat gaggacgcag actacagcaa gttgaagcgc agagcaagga atccagagac
    45361 aggtaaagtt gagtacgtgc ctgccgatat gacttataaa gagtggtata gcaagtatgt
    45421 tgcgaaagat gtaaaaaatg aaatacaaga ttataagaaa agtgacaaaa ccgtttcaag
    45481 atataatacc ccaaaattgt tttctgatgt tagtaacgca tgggatgaaa ttgggagggg
    45541 tggattatcg aaagaacaac ttgtagactt gctagaatct gaatatgaat taggtaattt
    45601 ttcgagcgat atagcaaaat tgataggagt aagttctgct tatatagatg ttagtagttt
    45661 agctacttca ttagtgagac atggacaaca gtactcctta gatgagttta tgttaataaa
    45721 agaggcggtt caaaaacctt atttgattct agataattca gagagggttg aaaaatcaat
    45781 tatttcatat gtaaaaatac ctaacaaaga taaggtcatt atggaagcgg tgatggtgcc
    45841 acgagatgaa atgctagtca ttcactttaa caaggtgggg attcgtcaag ttaaaaagaa
    45901 tgaaaaaaat atgtcgacgc tttacaaaaa gggaaaataa tgctatactc ttggtaaaga
    45961 tagaggttga gaatctgtca ccaacgcgcc acttatagtg ggtcgagaaa tgcaggagcc
    46021 ccgacagtcc tgcctatctt gcgcttagat agtaatctag gcgctttttt gttgcaataa
    46081 accactataa accgcatcga aatctaggcg gttttcttat gccctaaccg tatggaatcc
    46141 cgtacggttt ttatattgtc caaactgtac cgatgacaat aaaagctgtg ctgttccgtc
    46201 gccggacgta aagcgagact atcgagtggc gacgtaatcg ctggaggaca attatgtcag
    46261 aagaaatcaa tgcaactgta tctactgaat caactgagac tgtcgacact caagaaaatg
    46321 ttgatacagt gcaggaagaa aagcacgaac gaactttcac tcgtgctgaa atcggtaaga
    46381 tgctatctgc cgagcgctct aaatgggaag ctgagcaaga agccaaggaa aacgaagcta
    46441 agaagcttgc taagatgaac gctgatgaaa aacagaaata tcagttggat cagcgtgagc
    46501 aagaactagc tgaccgtgaa aaggctattg ctcgtaagga attgaccgca gaggctaaag
    46561 caatgctaag tgaacgtgac ttacctgttg agttagtaaa tgtagtcgat ttgacaaacg
    46621 cagagacggt atctgaatct atcacctcta tccaaaaagc atgggaagag tcagttcaga
    46681 agggagtctc tgaacgtatg aaaggtagtg cacctatcaa aaatgcacaa acagtccagc
    46741 aagaagtcac ggaaaaatgg cgtaaagact tcttgtaata aaagaaaaga ggaaaaataa
    46801 atggcatttg aagaattaaa cacagcagaa tcacgcaaga aacatcttgg gattattgag
    46861 gatgtacttg cagtaaattc atattcaaca ccacttgtga catcaagcga tgcagtaacc
    46921 ttgcaaggtc gctcttttac agtagcaact ggtaacacaa cagagttgaa agactacaaa
    46981 cgtaacaaag acaacgaatt tgatcacgtt gaagttgaag aaaaggttta tacccttgat
    47041 gaagaaaaat actggggtcg tttcgtagat caattggacg aacgtgactc taatggtcaa
    47101 gtgaatatca attatgttat tgcccgtcag gctgcagaag tagtcgctcc atatcttgat
    47161 gaactacgtt ttggtgcagc acttggaaac gtaagtgaca atgttgccat gggtaaaaca
    47221 gcaggagcga acaacgctta taatgcggtt cttgatgtgt ctgagaaact tgatgagctt
    47281 ggaattacaa aagaacgctt gctcttcgtc actccaagtt tctacaaagc gatcaagtct
    47341 gaaatcgttc gtctaccaca tggtgacgca gataagaaag ttcttggaaa aggatatgtt
    47401 ggtgaattgg atgattacac agtctataag gttccttcta aattcctgaa aggtgttaat
    47461 gcccttgcta ctgctccagg tgttgttaca tctccagtac aagtagataa tactaagtac
    47521 aacgataaca ttccagggcg atttggcgaa ttggtagagc aattgcttta cactggtgca
    47581 tttgttcttg aacacttcaa gaaatacatc atcacaattg cagattctaa gcctgctgct
    47641 aaaaaatcag cacaaggtaa agttgtaaac cgtgctaaag cgtggaaaac tggaacaact
    47701 tacaaaaaag gcgaatcagt aactcatgcc gataaagtct atgtagcggt taaggatatt
    47761 tctaattcag caaccgcacc agacacagat acaactaact ggaaagaaaa aactggtaag
    47821 aaataggtcc gagttatgaa atttaaaatc aaacaagatt tctatgattg ggaatcaaat
    47881 gtgaaacgac tggcaggaga ggaacttgag attactgagg agcgctatgc cgagctggct
    47941 gacaattttg ccagcaatgg tgtcgctatc tcagatgttc ttgaggaaat cctccctgaa
    48001 cctgagtttt tcgaagagga ttaatatgtc tatagagttg ctgaagaaaa tgacaggcga
    48061 agaagatact cagcttctca tgttgctcca aacgagggct acaaatctta tcttgtcaga
    48121 gactaatcga acatctttga cacctgcttt aagtctctta atacctgagg ttgctatcga
    48181 actccacaac cgctcaggag cggaaggaga gcattcaagg accgaaggtg gtatagcagt
    48241 agtctacgga gaaaacggcc tgtctacggg ccttttacag cgtatacgta tgcatagact
    48301 agcaagggtg gcaggccatg tttttgaagc agagtagact gaaaccttat ccaatgcgac
    48361 ggtttgaaaa gactgtcact gaggaaggtg tcgcaaaaga aggatatgtc aaggaagctg
    48421 agacaatccg tcttgagttg tggccagcta gtagtaaact acagtctgaa ttgtatggcg
    48481 agcgtgtcaa tgatattttg aacgcaaatg ccaacaagtc agctacaatc aaagtgaaag
    48541 atggtgtgtg tatcgatagc cagacagaag tgactcacag ggttatttct aaaaaggtct
    48601 acacacatca tcaagttttg gagttagagc gtgtcagggc tactaggggc agataggctc
    48661 atagctaaat gtagacgatt ggctagtaaa aaaactggag aggatatcgt cttacgtgcg
    48721 gtacacaatg ctgctataaa ggttgtccaa gctgatgcaa gaagactcgc accagcgaga
    48781 gatggagagc ttataattag tatcaaaact agagcaaaaa tggacggaga taaggctata
    48841 ggcgaagttt acaccaacct taaatacgct ccttacgttg agtttggaac aggaccaata
    48901 ggacaagcta accattcggg tatctctcca gaggtcagcg taacttacaa gtctaatcct
    48961 tggtatgtgc atgaagacca aatcaatgta ggaccgtacc actttcaaaa gattggggag
    49021 ttctacaaga tgtatggtca acctgctcag ccttatcttt atccagcttt gagagacaat
    49081 caagagcgtg tgtctaagaa tatttcgaat tatgtccgta gaaagataag agaacaaata
    49141 taatgatcaa tatcaagcct gttatttata aagaattgca aaaggtcgca gataatgtga
    49201 ctgatactta tcctagcgat tgggagaatt tcccagtcgt tattttttta gaagaacaaa
    49261 acaagccagg tgattggttt gacgacaagg aacaaaaatc ctctattcgc tataaggtgg
    49321 atatctttga tgataccagc actagtgagt tagctgttaa aatcaatcag atttttgagt
    49381 ctttaggttt gcgaagaacc gactgccaag acgtgccaga tccgtctcat ttgagacata
    49441 aggtcatgcg ctttgaaggt gtcgttgatt tagactcaga gcttgttttt caatttagaa
    49501 tggagaatta aacatgttag caaatggaat taaattggcc tttagtgaaa cgaaaggcaa
    49561 ttatcagaat cttgtagggc ttaaggaagt acctgaattt ggtatcgagc ccgaaaaagt
    49621 agaaaatact actcttgcag atacggtgaa gaagtacgag tttggtatcg gggacgcagg
    49681 agaacttaag tacaagttcg cttataataa ttcaagcgca acagctcctt accgtgtatt
    49741 acgtaaggca gcagatggca agaaaaaact ctactttgaa caaacctacc cagacggtac
    49801 taaggtcact tttgaaggtc aagtatccgt taaactgggc ggtggcggcg ttaatgccgt
    49861 tatcgagttc acacttaaga ttgcattgca gtctgaattg acattcgttg atggaattgg
    49921 aggttaatta aatggcgtta aaatacacaa cttggaaagt tactgacgaa aaagagttga
    49981 agctacgttt gacatctcat caagctgcaa ctgtggaaga aaaaatcggc atgaacttgt
    50041 taaagatttt catgcctgaa gctggcgaag agttcacttt accgcctttg aaagttatgc
    50101 tgttgttagt tcatggagcc ttgcagcagt atgaacatgg gtattccttt gaagatgtct
    50161 acgacctata cgatgaatac gtggataacg gcggagacca aacaaccttc atgacagagg
    50221 ttttaatgcc actctttgaa gtatcgggtt ttactccacg aggaagcaag ggcaagaaag
    50281 cttccaagaa gaaaatgaca gtagtcgagt aatcttaacg gtaacgcaga ttattgagag
    50341 gctttaccct atgtttttgg acatcggggg taagcctctt gatttttggg atttaacggt
    50401 gcttgaaatc agggaaatga ttgaaagcta caaccgtgtc aaaatccaag agcgtaaaga
    50461 gaagattatt gactcataca tactttcgag aatgataact aatcatgttt ccttattact
    50521 gtccaatgac gctaagattg ctgagctttg ggaatatgcg cctgatttgt ttgtagaaga
    50581 gaaacaagcg gtagaacaag aacgacaaag acaagcactt ttgttgcata aggaacggat
    50641 gcgtgatttt gcagagagac ataatcgaaa aaggaaggag gaagtaaatg gcaactcttg
    50701 acgaattgaa agtcatgatt gacgctgaga tagcgccttt caggaaaaag atgaaagaag
    50761 tcgagaatca ggtcaaagga acatctgacc aagtgaaaaa tgccactgcc aaagttcgtg
    50821 aacagtcgaa ttcaatcggt agtacgtttg gtaagctcgc taagtttgct ggttttgcaa
    50881 tccttggtaa gaaattgctt gatgttggga tgtattcaac gcagacagct cttgaagtat
    50941 cagcgtctat gaaccaaatt aagcgacaga tgggtgagag ttcgcaatct ttcttaaaat
    51001 gggttaacga taacgctaat gccatgaata tgggtgtggg cgaggctact aactatggtg
    51061 cagtctactc aaacttattt tctggattta tcaaagacac taacaagcta agcgcttata
    51121 ctgctaagat gttgcagacg tcggcagttg tcgctgaagg ctcagggcgc acgattacag
    51181 acgttatgga gcggattcgc tcaggtttgc tagggaatac ggaagcgata gacttttgtc
    51241 gcaccgctta gaaataggcg gattaagaac ttaccaaaat cggtaaaact ctaaatttta
    51301 agtaattaaa acatgacgat accgaggtaa actaagcaat taaaaaggct tagtcaccgt
    51361 agagcatagg gattgaacct gtgctttttg ttttgtcaaa aagtatagaa taaaatatcc
    51421 ccacgagtgg tgagcaccta gacaattcgg ttgtaggtga aaatatatgc cgaacttaca
    51481 agaaattgta agaagtatgg ataaaaagcc atgcgataac attattgaga agatctagga
    51541 atcaacgtca atgtggctat gattgagtcc actgaagcct ttaagaagtt cgcaaacgga
    51601 caaagctggc aacaattaga ctaccaaacc cagcaacaaa tccgccttat ggctatcctg
    51661 gaacaggcta cagccaagta tgggaatacc ttgtctaatt ctgtaaatgg tcgtatcagc
    51721 ctgtttaagt cgcttatgaa ggacgcagca ttgaaccttg gtaactctat gttaccgatt
    51781 atcaatgcca ttatgcctgt cttgaactct tttgctatgg ttttgaagaa cgtgacggct
    51841 aaactcgctg agtttatcgc tttgatgttc aacaagaaag caacagtgaa agatggtgtt
    51901 ggtggagcag ttggagacat gggtaacgcc atgaaagacg ctgcaggcgg agcaggagac
    51961 cttgctgacg cagtagacga tgctggagat tcagcaggag gacttgctga caatcttgga
    52021 gactccgcca aaaacgctaa gaaagctgct aaagagttgc taggtctttt gggatttgat
    52081 gagattaaca tcttgcaaaa accaaaagac gacgatgcag gcggttctgg aggcggtggc
    52141 aaaggtggta aaggaaaggg aggcggtggc ggacctttca aagacatctt gccagaagtc
    52201 gagttgaccg acatggacaa ccaattcaag agcattttcg atggccttgg ggataagctg
    52261 aaagggttgt ttgattatct aaaaaaactc tgggatttat ttaaaaaagg tttttctcta
    52321 tcctttagat gggatagtat tgaaagatta aagaatgcac tacaaggcat ttggaaatct
    52381 attaaagata tctttgaaga tggtactgta ttgcaagcag ctgcaaggtt tggagaaaag
    52441 ctagcttttg ctttaggaca aacgacgggc gctctcgcta acgtaatcat gggtattgct
    52501 gtctttatcg ctgaaagtct gaataaatca cttaatgaaa cgaaactaga tatcaaagca
    52561 tggttaattc gtatgtttga tattggtggg gaaatcgtcg aaagcgtcgg aaatattgcc
    52621 cagagtatcg gacaaatttt ctacgattca attacaagtg aactagctac aaatatgggc
    52681 gcaggcctat tcagtgcttt cacatacgct tttatgggcg tgaaagagat aaccgctaaa
    52741 tacacaaggg atataatcgg agctattgaa gaaactatca ccgaaaatca ggctggcata
    52801 acagaaatgt ttacgggtct ttttaaagct gtagatccta ttgctcaagc tttatcaagc
    52861 tcaatgaaga aactttttga aagtgttaat taagtatacg atgagcatat aaaacctttg
    52921 tttgaatcaa gttccgcctt gatgtcagat gtagttggtg cttttgttaa tggatggaat
    52981 gataatatcc aacctgtcct tgaaaagata ggtcacggtt tcgccgatac aatcaaaaac
    53041 catattgaac cagctttaga aaaaataggt ggcatgattg gaagttttgc cgacttttct
    53101 aaagcgataa atgaagtttt cggcccagtc atttccttta ttgtagaaaa gttaacggtt
    53161 gtactagccc ctgcaattga atacataaga gaagtttggc gtgttttatt taacactatc
    53221 tctgatgtga ttggtggtat tgctgatatc atcaaagggg tatttgatgt acttacagga
    53281 cttttaactg gagatggcga aaaaatcaaa gaaggatttt tgagtatatt tggcggatta
    53341 aaagatatag tagttagcgt ctttagtggc attattgatc ttgtatctgg tgtattgaaa
    53401 ctgctttggg acgttgttgt cgcaatattc aaaagcattt gggacgcaat tgtagctatc
    53461 ttttctggtg tcagctcttg gtttggagaa aagttccaag gtgcatggga tgctatcgtt
    53521 aacatcttca gtaatctagg ctcatggttc ggacaacgtt gggcggatgt gactagtgct
    53581 ttagctaata tcggggcatg gtttacgaat atgttccaaa aagcatggac tggcttaaca
    53641 aacatcttta gcaaactagg ttcatggttt ggcgatagat ggaacgatgt tacaagtgcg
    53701 ctttctaaag tagcgagctg gtttggcgag atattcggaa aagcttttga cgcagtaaaa
    53761 gatgctttta gttctattgg cgacttcttt aaaggcgttt gggatactgt caaaagtatc
    53821 ttcgttaatg ctggtcagat ggtcggcgag gcagtaggtg gagcgtttaa gagtgcggtc
    53881 aatgcggttc ttggaacgat tgaaaatgta gtcaatggtt tcatcggaat gattaatgga
    53941 gttttaggcg ttgtcagaaa cttacctggt ctaggatggg ttggtagtgt aagcacagtt
    54001 agcctccctc gtcttgcccg tggtggtatc gtcgatagtc caacaatcgc catgattggt
    54061 gaagctggta aagaggcggt cgtaccactt gaaaatacag gatttatcca aacacttgga
    54121 cgagtagtca gcagtgcggt agtaaatgcc atggctggtg ttagtccaca aggtggattc
    54181 tctggcgacg gcgacatcgt tatccaaatc gcaggccatg agttcggacg ggtagccatc
    54241 caagaaatca acaaggaaca tgaacgagca ggtcaaacct tgctcaagat ttaggaggtt
    54301 aaatggcaca attgacaatc aatggggtgg ctgtgaagcc tcccaaatct tttcaagtcg
    54361 gtattcaaga tatcgatgga gagacagggc gtaatgccaa tggcgatatg gtgcgtgacc
    54421 gtatcacgac caaacgaaaa ctagactgtg aatggggcat gctgactcag gaagaaatga
    54481 gtcagctttt aaatgctgtt tcagcagtct tttttgaggt ctcatatcct gaccctgtta
    54541 aaggtcagac gactgggact ttctacgtcg gtgataggac agctcctagc tatagcttta
    54601 ctgagaagtt taaaccttgg tctggcgcta aatttaatct ggtagagagg tgagaaaatg
    54661 gacgctttaa tcagacgaca gtttgacaga gctatgtttg ccaaggatag gacgctggct
    54721 attcgtgttg gtgattatgc ttcacgagat atcaaagagg ctagttttga gtatggctat
    54781 atcaaaggcg atacttacaa acccggtgga acgtgtgccg gtagcggtaa gattaccttt
    54841 accagtatca ttaccacgtt caataaactg gatatactac accctgagat tggtctattg
    54901 gttgggacta cctaccagtg ggttaagatg ggggaatact tcatcaatga tattgagatt
    54961 gaccgaaacc gaaacacaac cacgcttgaa ctcatggatg gtatgtttaa gctcaatcgt
    55021 gagtatgtga cggacttaca ttttccagct gaagtacgag aggttattca ggaaatctgc
    55081 ctgaaaacag gcattgagtt agcgaatgac tatttcggaa tcagcgctat gcgttaccat
    55141 atcgagcaag ttcctgaggg caagaaactt tcctttaggg atatgctgag cgctatgact
    55201 cagatgattg ggatgtcttg tttcttcaac agagaaggca agatggaaat ccgtgatttg
    55261 actgagtcca atatcacgat caacgctgac agttacttct tgtatggctt gaccaagagt
    55321 gagattgagt atcagatatc tggtatcact tgtaagacgg acaagaagtc tctgacggtc
    55381 ggtatgaaga caggtcggtc tttggaactg gacaatgtct tcatgaccca gagcgcttta
    55441 aatgacctgt attacaaact gaaaaaccta acttactatc cgtataatct caactaccaa
    55501 ggacatttgt tacttgaggt tgggcagtgg gtaaccattc agaccaacaa gaaagagact
    55561 tttaaagttc ccgtgttaag tcagagcttt acctttaaag gtggtctgag aggtcgtatc
    55621 agtgcagata gtaaggccgg aaacgatacc cagtattctt acgagggtac gattaccaag
    55681 cagattaagc aacaagatgg cattgaagcc aaaatccaag cgcagattga agcagcagat
    55741 aaagattctg accaaaaggt cgacaaaatc aaaaaagact ttaacgatca agtagaactt
    55801 gccaaagcca gagctgaaga agtcaagcaa gaactgtctg acactatcaa tcagcgcttt
    55861 aatagctttg acaacgggcc attgaaagaa actaagcgca aggctgagga agctttgcga
    55921 aatgctggcg caagtaccct gcttgcacag gaagttaagc ggattggact ggattctgtc
    55981 gctagacttg gagcgtttaa gtcgcagact acgagcgcac aaacggctct gtcaggtgac
    56041 ttggacgctc tgaaacagac ggtcacaagt gaggtcaatc aagcttcaga gtaccgcaga
    56101 acgaccacag aggtccttag tcgcatgact ggccagatgg acggatttgc gacgaaatct
    56161 gaagttagac aagatgtggc tggtctgaca gagacatttg ctaaacttaa aactgatacg
    56221 aataatttga tttctggagc taaaagtgaa atcactctag caaaaacaga atttcagaaa
    56281 acagctgatg gcctatctgc taagatgtca gcagttgagc gttacgttaa tcaagatggt
    56341 cagcgacagg aagccctaca gcgctatact cgtgaggaga gcgctcgtca agtcagcgcg
    56401 gttcgtgagc agatatccag agattatgtt gggaaatcgg cttatcaaga agatgtgaga
    56461 ggtctagaac gtcgatttag tgcgataagc acccagacga acaatgatat agctaggaaa
    56521 atcgctcagt acaagcagac agtcgatgga caatttgcaa gtattacgtc tcaaatagct
    56581 ggtaaggcta atcagactga cttccagcgt gttaaggaaa ccagtaaact ttacgagcgg
    56641 attctgggta atagtaaaaa cgggattgca aatacgattg caagaatggc tatgacccat
    56701 cagctctttc aggttgaagt atcgaaaaac gaccatctga aaaccgttca gaggcagctg
    56761 gcaggttcct ggtcggttca aaacatcaac agtgcaggtg atttgatttc gggcattaat
    56821 ctaggagcca atggacataa ccgctttgtt gggaaattga cccacatcac tggcgagacc
    56881 ctgattgaca gagcagtcat caagtctgcc atggttgata agctcaaaac ggccaatttt
    56941 gaagctggtt cggtaacgac tacgatatta gacgctgaag cggtcacggc tgataaagtg
    57001 agatttgatg ctgcgtttat taggaaaatg actgcaaatg acgcttttat tgaccaactg
    57061 acatctaaac gtatcttctc tactaaggtt gagtccgtca tttctagttc aaccttccta
    57121 gaagcctatc aaggacgaat cggtggattc actattgggc gttttgctca aggaagaggt
    57181 cgctggattt ctggtatcaa ccaattctca gttggcatgg ggaatggtga aggaggaggc
    57241 tataatggcg aaaataccgc attttgggcg aactggggtt acagttggaa ctctcctggc
    57301 cccaatgctt ggtatgtaac aacatcagga aatatgtatt gccgaaacgg agcagatttc
    57361 catgggaagg ttgacttttc gaattcatcg agagcaaact tttatgggaa tactactttt
    57421 tctcgttctc ctgtgttttc aaatggtatc gaacttggaa gtaaagacgt ctttggtgat
    57481 ggttggaatc ccaaaggcgg aaggaatgcg gttgtttggt ggaatcaggt cggtagtggt
    57541 agcgtgaagt attggatgga acaaaaatca gacagacgcc taaaagagaa catcacagat
    57601 acagctgtga aagccttgga caaaatcaac agattaagaa tggttgcatt tgatttcatc
    57661 gaaagtaaga aacatgagga gattggtcta atagctcaag aggctgaaac catcgttcca
    57721 agaattgttt cacgagatcc tgagaatcca gatggctatc tacatataga ctataccgct
    57781 ttagttcctt acttaatcaa ggccattcaa gaattaaatc aaaaaataga aaaaatggag
    57841 aaaacaatag catgaataac aacatgttga ccaatatcgc acttaaagca attcaggagc
    57901 ttgctcttga aaatagaaaa cgaacagata gattggagaa cttagaaaat gaacgcagaa
    57961 cagcttaacc aagccttaca aatgacaatt agtgaaatgt caacaacttc aacaaattcg
    58021 atgattacaa gtaatgtctt gagtattcag ttggatgagc aaagggaaga gaatcaaaga
    58081 cttcaagcac gagtggatga gctggaagct ctgcttgatg aacaaactaa accagcagac
    58141 aaaggagaat agacatggca aaaacaattc aaaacacaga taacttgcta gaccttacaa
    58201 aaatcacaga accatttgat cttgcgagtg ctttgcgcta catgaaagaa agtggagagt
    58261 tcattcgttg caagaatgta aacgatgact tctatatgta tcgtgatgtt caaaaacgtc
    58321 ctgtgttcgt aaatggccgt cgccaattca aggatgttga aaccgtttgg gcgttcaacc
    58381 agtggggtgg tacaatcaca acaatcaacg tagccattct gttgaatcag gaattctata
    58441 tcatgaaatt tgatgcagag ggcaatcctg actggacgga tccaacggta gaacctaaag
    58501 aataggaggt tgtatgccaa ttgaagaagc tgaaaaaatc gctcaaagtc aggtagcttg
    58561 ggcgattttg tttatcttgc ttttctttat tatcattcga tatcttatca agacttcgga
    58621 caagcgagag aagaagatta tggatttgca cgagcaatca aaggccgact ctaatagacg
    58681 agaagagcgt ttgatgactc atctagaaaa gaccactaca gaattaacca caatcactca
    58741 cgcggtcgga gacattcaaa aagaaatggt tcgcatgaac gaccgcatgg aagaaatcga
    58801 aaaaggagaa taacaaatgc aacaaattac tgaaatcatt actaatggag caatcagcat
    58861 cctagtcatt ttggcagggg ttgtagttag ggcagtcaag gaatacctcg tcaaaaaagg
    58921 tggagaaaag actatcaaga ttgttgaaat cttggccaag aacgcagtta atgccgtgga
    58981 gcaggtagct gctgaaactg gctacaaggg agatgaaaaa ctggcacagg ctcgcgctaa
    59041 aattcgtgct gagcttacaa aatacaatat tagcatgact gacaaagact tagacacctt
    59101 cgtagagtca gcagtgaagc agatgaatga cgcatggaaa ggacgatagg gaatggatat
    59161 cgatagaaac agactacgta caggcttgcc acaggttggg gtgcagcctt atcgacaagt
    59221 acatgctcac tcaacaggca accgcaactc aaccgtacag aatgaagcgg attatcactg
    59281 gcggaaagac ccagaattag gttttttctc gcacgttgtt gggaacggtc gcatcatgca
    59341 ggtaggacct gtgaacaacg gaagttggga tgttgggggc ggttggaatg ctgagaccta
    59401 tgcagcggtt gaactgattg aaagccattc aactaaagaa gagttcatga cggactaccg
    59461 cctctatatc gaattgctac gcaatctagc ggacgaagca ggcttgccga agactcttga
    59521 tacagacgac ttggcaggta tcaagacgca tgaatactgt accaataacc aaccaaacaa
    59581 ccactcagac catgtggatc catatccata tcttgcaagt tggggcatta gccgtgaaca
    59641 gtttaagcaa gacatcgaaa acggcttgag cgctgcaaca ggctggcaga aaaatggcac
    59701 tggctactgg tacgtacact cagacggctc ttatccaaaa gataagtttg agaaaatcaa
    59761 cggtacctgg tattatttcg atggctcagg ctatatgctt tcagaccgct ggaagaagca
    59821 cacagacggt aattggtact actttgacca atcaggcgaa atggccacag gctggaagaa
    59881 aatcgctgag aagtggtact attttgatgt agaaggtgcc atgaagacag gctgggtcaa
    59941 gtacaagaac acttggtact acttagacgc taaagaaggc gccatggtat caaatgcttt
    60001 tatccagtca gcagacggaa caggctggta ctacctcaaa ccagacggaa cactggcaga
    60061 caagccagag ttcacagtag agccagatgg cttgattaca gttaaataaa tagaaaggaa
    60121 actttctaaa ttgttctttc accgcaggct caggcttgcg gtttttttgt ttgctcaaaa
    60181 ggggcaaaaa aggggcaaaa gtgtcgtaaa tctctgtaaa atgatgtaaa aacatttatt
    60241 taaaagctca aaatatagct gttttaaaag gtattgtaag atatagtaaa acgatgtaaa
    60301 ggtattttta aatgcggatg aattataaaa ccacgaatcc tatgtgactc gtggttcttt
    60361 tttataaact ggtagagtgt tttggttgta ctttttgttc agggtcaatg tagttgatag
    60421 cgttgttgac agcagttgga gcttctccga ggcctgtcgc aatcagatca atttttccgt
    60481 catagtagca gcagtcaccg atagcataga tacctgcttg gctggattcc tgtttgctgt
    60541 tgacgataat cttgtgacgg ttgaggtcga gcccccagtt tttaaggtta ccgacagaag
    60601 atttgaaacc atagttgaca aagaggtggt ctaggtcaat ggtttcagtt tcatcagatt
    60661 tgacttttgt gatttcaagt ttatcaagcg tttttccatc tccaaggagt tggctagggg
    60721 tgaatggtgt cttgatggtt acagatgatt cttgcaaggc ttgaacactg tgttccaagg
    60781 cacggaaatt atctctgcgg tgaacaaggg tagttggtgc gattttttca aaagccaaag
    60841 tccaatccac agccgaatct cccccaccaa gaatcgtcac tttcttacca gcgtattgct
    60901 gaatgttaga aacgtggtag tggatatttt catagccctc aaccccttca agttccagcg
    60961 gacgtggttt gaaggcaccg ccccccatag cgatgataac tgttttagtc aggtgacttc
    61021 ctttagaagt tgtgatggca aattcttctt cttgtttgtc aatctcaaga accgtttcat
    61081 tgagatgaat aggggtatca aatccattta gctgttcaat caagcggtta gtcaactctt
    61141 ctccagtcag gtttgggaag cctggtacgt ctaggatttc cttttcaggg tagagaatag
    61201 caggttgtcc acctagctgg ggaagagagt cgatgatttg aaccttggct tggcgtaggt
    61261 gggcataaaa ggctgcaaaa agcccgacag gaccaccacc cacaatggta atatcataga
    61321 gttgagacat agtttctcct ttgttttttc tagtcagttt attttatcat atttttgttc
    61381 aatataaaat ggactaggat agggaaaaaa atgccagaaa atggtataat aggacgaaag
    61441 tgttttgata gggaggatat cagggatgaa ttttcaacaa ttatccaatc tgcaatattg
    61501 gaccagtttg tttgcaagtc catggacgat agctatcaat ctgattgata ttttgattgt
    61561 tgcttatatt ttataccatt ttacaaaaac tattgcagga accaagatta tgattttggt
    61621 acgtggagtt ttggtgttta ttttagctca aatccttgca aatatgattg gtttgactac
    61681 gatttcttgg ttaatcaatc aaattattac ttatggggtt attgcggcgg ttgttatttt
    61741 ctctccagag attcggactg gtttggaacg tttgggaaga gcgacagatt tcttttccaa
    61801 tgcccctatt agtgctgagg aacagatgat tcgtgccttt gttaagtctg ttgaatacat
    61861 gagtcctcgt aaaatcgggg ccttggttgc tattcagcgt gtacgtacct tgcaggagta
    61921 tatttcgaca ggaattccct tggatgctaa gatttctgca gaacttctca ttaacatttt
    61981 tattcccaac actcccctac atgatggtgc ggtgattatc aaagaagaac gtatcgctgt
    62041 gacgtctgcc tatctgccct tgacaaaaaa cacagggatt tccaaggaat ttgggaccag
    62101 acatcgggcg gctatcggtt tatcagaagt ctcagatgcc ttgacttttg tcgtatcaga
    62161 ggaaacggga ggaatttcga taacctataa tggaaggttt aagcacaacc taacacttga
    62221 tgaatttgaa acagaattac gtgaaatctt acttccaaaa gaggaagtgg gtcttagttt
    62281 taaagaacga ttgctaggag gatggaaaca tgaaaaaaaa tagtttatat atcatatcct
    62341 cactcttttt tgcttgtgtt ttatttgtct atgctacggc gacgaatttt caaaacagta
    62401 ccagtgctag gcaggtaaaa acggaaacct atactaatac agtaacaaat gtccctattg
    62461 acatacgcta taatagtgat aagtatttta ttagcggttt tgcttcagaa gtatcagtgg
    62521 tcttgactgg tgcaaatcgc ctatcgctag ctagtgaaat gcaagaaagt acacgtaaat
    62581 tcaaggttac tgctgaccta acagatgccg gtgttggaac gattgaagtt cctttgagca
    62641 ttgaagcttt acccaatggg ctgaccgctg tggcgactcc gcaaaaaatt acagtcaaga
    62701 ttggtaagaa ggctcagaag gataaggtaa agattgtacc agagattgac cctagtcaaa
    62761 ttgatagtcg ggtacaaatt gaaaatgtca tggtgtcaga taaagaagtg tcgattacga
    62821 gtgaccaaga gacattggat agaattgata agattatcgc tgtcttgcca actagcgaac
    62881 gtataacagg taattacagt ggttcagtac ctttgcaggc aatcgaccgc aatggtgttg
    62941 tcttaccggc agttatcact ccgtttgata caataatgaa ggtgactaca aaaccagtag
    63001 caccaagttc aagcacatca aattcaagta caagcagttc atcggagaca tcttcgtcaa
    63061 cgaaagcaac tagttcaaaa acgaattaaa aatagaaaag gattttataa caatgggtaa
    63121 atattttggg actgatggag tccgtggaga agctaaccta gaactaacac cagaattagc
    63181 ctttaaacta ggacgttttg gaggctatgt tcttagtcaa catgaaacgg aagcgccgaa
    63241 agtctttgta ggacgtgaca cacgtatttc aggggaattg ctggaatcgg ccttggtggc
    63301 aggtctcctt tcagtaggga ttcacgtata caaacttggt gtccttgcaa caccagcagt
    63361 agcttacttg gttgaaactg aaggagcaag tgccggtgtc atgatttctg ctagccacaa
    63421 cccagccctt gataacggaa tcaagttctt tggcggtgat ggcttcaaac tagatgatga
    63481 aaaagaagca gaaattgaag ccttgctaga tgctgaggaa gacactcttc ctcgtccaag
    63541 tgcagaaggc ttaggaattt tggtagatta tccagaaggc ttgcgtaagt atgaaggata
    63601 ccttgtttca actggaactc ctcttgatgg aatgaaggtt gccttggata cagctaatgg
    63661 agcagcttct accagtgccc gtcaaatctt tgcagacctt ggtgcccaat tgacggttat
    63721 cggggaaaca ccagacggtc ttaacatcaa ccttaatgtt ggttcaacac atccagaagc
    63781 ccttcaagaa gtggtcaaag aaagtgggtc agctattggt ttggcctttg atggagacag
    63841 tgaccgcttg attgctgttg atgagaatgg tgacatcgtc gatggtgaca agattatgta
    63901 catcatcgga aaataccttt ctgaaaaagg acaattggct aaaaatacaa ttgtgacaac
    63961 tgtgatgtct aaccttggtt tccacaaggc cttgaatcgc gaaggtatta acaaggcagt
    64021 tactgcagtt ggtgaccgct acgttgttga agaaatgaga aaatcaggct acaaccttgg
    64081 tggtgaacag tctggtcacg ttatcttgat ggattacaat accacaggtg atggtcaatt
    64141 atcagcagtt caattgacta aaatcatgaa gaaaactggt aagagcttat cagagttggc
    64201 ggcagaagta acgatttatc cacaaaaatt agttaatatc cgagtggaaa acgtcatgaa
    64261 ggaaaaggcc atggaagtgc cagctatcaa ggccatcatc gagaagatgg aagaagaaat
    64321 ggcggggaac ggccgtatcc ttgttcgtcc aagtggaaca gagcccctct tgcgtgttat
    64381 ggcagaagcg cctacaacag aagaagtgga ctactatgtt gataccatca cagatgtagt
    64441 tcgtgctgaa attgggattg actaaatcct agaaaactag atgaaaataa aaaattatgg
    64501 tacaatagct tataatattg tagccgatgg agaaagacat gaatcttaaa cgtgaacaag
    64561 aatttgttag tcagtatcat tttgatgcgc gtaattttga atgggaaaat gaaaatggag
    64621 ctcctgaaac caaggtggat gtgaatttcc aattgctcca atatgaccaa gaaaatcaag
    64681 tgacttcctt gattgtcatc ttgagcttta tgattgtatt tgataagttt gtcattagtg
    64741 gaacaatctc acaagtaaac catatcgatg gccgtattgt caatgaacca agtgaattga
    64801 accaagaaga ggtggaaacc ttggctcgtc catgtttgaa catgctcaat cgattgactt
    64861 acgaagtgac tgaaattgca ttagacttac caggaattaa tttggagttc taatatgaaa
    64921 ttagctgttt tcacagattc ctctgcttat ctcagtgaag agaccttgca aagagaagac
    64981 ttgtttgtct tggatattcc tgtcaatatt gatggtgagg aatatgtcga aggcatcaat
    65041 ctgtctgctg aggaatttta ccaaaaaatg gctcaggctt ctgaattgcc taagaccagt
    65101 caaccaagta ttgccaagtt agatgagatt ttaacttcgc tcaaagaaca aggctataca
    65161 catgccttgg ggcttttcct atcttctgga atttcaggtt tttaccaaaa tatccagtat
    65221 atggtcgatg actatgaggg cttaaccatt gcttttccag acactttgat tacaagtgct
    65281 cctctgggta tcatggttga aagcgtcttt aattggcgtg atcagggcga tgattttgcc
    65341 agcattcagg ataagctagc cattcaaatc agccgtacgt cagcctttat catggtagat
    65401 gacttggatc atttagtgaa aggtggacgc ctttcaaatg gggctgccat tttgggcaat
    65461 ttgcttagca ttaagccaat cctttatttt aacgatcaag gtgtgattga agtttacgaa
    65521 aaagttcgta ctgaaaagaa ggccaccaag cgcttaattg aaattatcaa ggaaacaacg
    65581 gcttcaagtc aatacagggt cattgtcatt catgggaatg ctcctgaaaa ggctgaagaa
    65641 ttgcgtcagc atttgcttga ttttggcttg ggttcggatg tttcacttgc tacatttggt
    65701 agtgtcattg gaacgcacct aggagcagga agtattgctc tgggttatat tccagtgatt
    65761 tagttggcgc ttctaggcta gttaagatgc cttgtatctt agcaattgaa cacggactac
    65821 ctgcctcttg aaaaaagatg tctgtcttgc ctttcgtgga aagtcagtgc catttcctat
    65881 tttttatggg tggctaagat cctttgtatc ttgataattg aacacgcctg gaaccctgtg
    65941 tgaaaaagat agttcttcca aggagtagac acttcttgat cagaattcct attttcactt
    66001 tgtgttctta caggctttgt atcttagaca ggagtagaga tgagtattcg agtaattatt
    66061 gccggtttta agggaaagat gggtcaagct gcttgccaga tggtcttgac tgattcagat
    66121 ttggacttgg tagcagtttt ggatcctttt gagtctgagt cagaatggca gggtattcct
    66181 gttttcaagg ataaggctga tttagctggt tttgaagcgg atgtctgggt agactttact
    66241 actccagctg ttgcctacga aaatacacgt tttgctcttg aaaatggctt tgctccagta
    66301 gttggaacga ctggtttcac gagtgaagaa attgcagagc taaaagaatt ttctcgtgcc
    66361 caagacttgg gtggcctgat tgcccctaac tttgccttgg gtgctgtctt actcatgcaa
    66421 tttgcgacgc aggctgccaa atatttccca aatgtggaga ttattgagct ccatcatgac
    66481 aagaaaaagg atgctccgag tggaacagcc attaaaacag ctgagttgat ggcagaggtt
    66541 cgagagtcaa ttcagcaagg tgcagcagat gaggaagagc tgattgctgg tgctcgtggt
    66601 gctgactttg atggtatgcg catccactca gttcgtttgc caggcttggt agctcatcag
    66661 gaagtcatct ttggcaatca gggagaaggg ttgaccctcc gtcatgactc ctatgatcgc
    66721 atctccttca tgacaggagt caatttggga attaaagaag ttgtcaagcg tcatgagctt
    66781 gtctatggat tagaacactt attatgagat taacgcaaat gccttctgaa tttcagaagg
    66841 ctttaccagt attagaaaaa attaaagaag caggctttga ggcttatttt gttgggggct
    66901 ctgttcgaga tgcccttctc catagcccta tccacgatgt ggatattgcg acgtcttctt
    66961 atccagaaga gaccaagcag atttttccgc gaacagccga tatcggaatc gagcatggaa
    67021 ccgtcttggt cttagatggg gatgaggagt atgaggtaac aacctttcgg acagaggatg
    67081 tctatgtgga ctatcgcaga cccagtgcgg tttcctttgt gcgctcgcta gaagaagacc
    67141 tcaaacgccg tgatttcaca gtcaacgcct ttgccttgga tgagacagga gaaatcgttg
    67201 acttgttcca tggtttagaa gatttggaaa agcaagtctt gcgagcagtt ggagtggcta
    67261 gtgagcgttt caacgaagat gctttacgga ttatgcgtgg tttccgtttt caggctagtc
    67321 ttggttttgc acttgagcca gaaacattta aagctatgaa gaccttgacg ccgcttttgg
    67381 agaaaatttc tgtagagcgt accttcgtcg agtttgataa actcttgctg gctccatttt
    67441 ggagaagggg cttggcttcc atgattgaga gtcaagctta tgactatctc cctgatatgg
    67501 catctagccg ggacaagctc aacagactgt ttgatttgga gactgatttt acttttgaat
    67561 cctctgaaca agcctggtcg gctttactat gggctttgga gattgaaaat gcgcagtcat
    67621 ttttgaaatt ttggaagacc tcacgccagt ttgccaagca agttcaggat ttgctgatta
    67681 ttttggctct gcgtgaaaat ggagaattga gcaagcgaga ttgttatcgc tttgacatag
    67741 atttgctttt acaggctgaa aatcttcgtc aagctcaagg aaaagaagtc aacccacaag
    67801 ccatcacaga aaaataccaa agcttgacta tccatgacaa gaaagagatt cagattaatg
    67861 gcggtatttt gatcaaggaa tatggctatc agccaggccc agacttggga gagattttaa
    67921 cagagattga gtttgccatt gtcgatggag aattggagaa taatcgtgaa gccatccatg
    67981 cttacctgag ggagaaaaaa tgagtgattt tatcgttgaa aaactaagta aatccgttgg
    68041 tgacaagacc gtttttaggg atatttcctt tattatccat gacttagaca gaattggttt
    68101 aatcggtgtc aatggaactg gcaagaccac ccttttggac gtcctttctg gtgtttctgg
    68161 atttgatggg gatgtcagtc ctttttcagc taaaaatgat taccagattg gttacttgac
    68221 tcaggatcct gattttgatg atagaaagac agttttggat acggttctat ctagtgaact
    68281 caaggaaatc cagctcattc gtgagtatga attgattatg ctcgactata gtgaggacaa
    68341 gcaggcgcgt ttggaacgtg tcatggcaga gatggactct ctccaagctt gggaaatcga
    68401 gagtcaggtc aagaccgttc ttagcaaatt gggcattcaa gacttatcta ctcctgttgg
    68461 ggaattgtca ggtggtctga gaagacgggt acagttggca caagtcttac ttggcaacca
    68521 cgacctcttg cttttggatg agccgaccaa ccatctggat attgcgatta ttgagtggct
    68581 gaccctcttt ttgaaaaatt ctaagaagac cgtccttttt atcactcacg atcgttattt
    68641 cttagacgct ttgtccacac ggattttcga gttggagcga gcaggcttga cagaatatca
    68701 gggcaattac caggactatg ttcgccttaa ggcagaacag gacgagcgcg atgcagctct
    68761 acttcataaa aaagaacaac tctacaaaca agaactggcc tggatgcgca gacaaccgca
    68821 ggcgcgtgcg accaagcagc aggctcgtat caatcgtttc cacaacttga agaaagaact
    68881 ttcaggtggc gttgctgaga cagacttaac tatgaacttt gaaaccagtc ggattgggaa
    68941 gaaagtcatc gagtttcagg atgtttcctt tgcctatgaa aacaagccca ttttgcaaga
    69001 ttttaatctc ttggtacagg tcaaagatcg tatcggaatt gttggggaca acggtgttgg
    69061 aaaatcaacc ttactcaact taattgcagg aagtcttgag tcaactaaag gacaagttgt
    69121 gattggggaa actgttcgca tcgcctattt ctctcagcaa attgagggct tagatgaaag
    69181 caagagagtt atcaattacc tgcaggaagt ggcagaagag gtcaagacca gtggcggttc
    69241 tacgacttcg attgcagagt tgctggagca gttccttttc ccacgttcga cgcatggaac
    69301 cttgattgag aaattgtcag ggggtgagaa aaaacgtctt tatctcctca aactgctttt
    69361 ggaaaaacca aatgttcttc ttttagacga gccaaccaat gacctagata ttgcaacttt
    69421 gacagtctta gagaatttct tgcaaggttt tgcaggtccc gttttaacag tcagtcacga
    69481 ccgctatttc ttggataagg tagcgaccaa gattctcgct tttgaggatg gcaagattcg
    69541 tcctttcttt ggtcattaca ccgactatct tgatgaaaaa acttttgaaa cagatatggc
    69601 caatcaagtg caaaaggccg aaaaggaaaa agtggtcaag gttcgagaag acaagaaacg
    69661 catgacctac caagaaaagc aggagtgggc aagtattgaa ggtgatattg aagccttgga
    69721 aaaacgtatc gctgctattg aagaggaaat gcaggctaac ggctctgact ttggtaagct
    69781 ggctactctc caaaaagaat tggatgagaa aaatgaagca ctccttgaaa aatacgaacg
    69841 ctatgagtat ctcagtgaat ttgatagtta agactattcg aaaatcaaag tgcaaactat
    69901 gtcggcttca cattgccgac tcaagtacag cctgtgaccg gcttcctaat ttgcactttg
    69961 atttttattg agtataaaag aatagaaaaa tcccgtctca tgaaaggatt tctctattct
    70021 tttttggttt cttgatgaaa gatattttgc caggtttcgt ggcgacgcca gatactggta
    70081 tggatgatac catctaactc atagcagatg agtttggttt tttgactgat ggaagtaatt
    70141 tgaatgtcct tgatagcaga atttaactct tttttggtct tataagcctc tttatccatc
    70201 tgctctccat cttggcgaat atagacaaaa tcatcagtca agagttcttc tagttggttt
    70261 ccttggtcaa tcaattgttc acgcataagc aattttttat agacattgtc taaaatttca
    70321 tcctcaggga taggtgctgg ttcgatatgg acatcggtat caaagacgcc aaaacgctcc
    70381 tccagcatag actcgacctg atccgcgatt tcatggcttt caaaaacaga caagtcagga
    70441 ttcatctcta gtgtaatatc caggtagatg ttgctaccgt aggtgcgacc tctttgcgat
    70501 ttgaccttgc tgattttggg aatttccatg atagcctttt ggtagtcctc gagcaggcgg
    70561 tcgtcaaagc catctgaaag actaaaggaa gattcgatga agatatcata ggcagtcttc
    70621 aagataaaga aagtgatgat gatagcaacc agtttatcca caatcggata attgaaacta
    70681 ctagctagga tggcaatggc ggttccaagt gaggtaacag cgtcagaaag attgtcctta
    70741 gcagctgcct tcagcgcctt ggagttggat ttcttactga ggcgagtatt gtagagatag
    70801 accacaaaca taatcgctgc agaaatgatt cctagagttg caccaagagg atcaatgacc
    70861 gtttcttccc gactgagaat cttttgaatg gtatctctta gaacatcgaa accgacatag
    70921 aacatgatga tagaagtgat caagcttgcc aaatcttcaa tcttccaatg accaaaacgg
    70981 tggtcacggt ctgcaggctg gcgcgccatc cgaatcccga ttaagagggc cacatttcca
    71041 atgatgtccg atacgttatt aaaaccatcg gccaccaaac tggatgaatg aaggagatga
    71101 ccagctgcta atttggctgc agacaagatc aaataggtcg aaatactgat aatggctcca
    71161 cgctcagcta acttgagatt tgagatagat tgcttcattc aacttccttt ctagtcacat
    71221 agcattctac cattatactg gttttcaagg aaaaattcaa ataaggcagt ttttactctt
    71281 tgaaaactcc ccaaaatttg gtataatggt actactcaag ggagtagctg gcagaaacct
    71341 gtgatagtgt cgtcattccg aattttatgc tgaaaagtat gctttccggc cctatcttaa
    71401 acagcgagac ttgttatgat taacaggtct ctttttgttt gtcgtgaaaa gatatgacag
    71461 aaagagagtc tgttttgcac acaatgtcaa ggaggagaca catgtcaaaa gaacaaaaac
    71521 gccaagcgtt ttatactcag agccctgaag aggtcttgca ggctgtggat gcgaccgagc
    71581 aaggtttgtc atcaagtgag gcggaaaagc gccttgccga atttgggcac aatgaactcg
    71641 aagaaggcga gaaacgatca atcttggtca aattcatcga gcaatttaag gatttgatga
    71701 ttatcatcct agttgcggca gcaatcttgt cagtcgtgac ttctggtggg gaagatatcg
    71761 cagatgccat tatcatccta gctgtggtta tcatcaacgc tgcctttggt gtttaccaag
    71821 aaggaaaagc tgaagaagct attgaagccc tcaaatccat gtctagtcca gttgcccgcg
    71881 ttcttcgtga tggacacatg gcagagattg actctaaaga attggtacca ggcgatatcg
    71941 ttgcccttga agcaggtgac gtggtaccag cggacctacg tttgatagaa gccaactctc
    72001 ttaaaattga agaagcagcc ttgacaggtg aatctgtacc agtcgaaaaa gacttgtcag
    72061 tcgagcttgc gacagatgct ggtattggtg accgtgtcaa catggccttc caaaactcaa
    72121 acgtaaccta tggtcgtggg atgggtgttg ttgtcaatac aggtatgtac actgaagttg
    72181 gtcatattgc tggtatgctt caagatgcgg atgagactga tacaccactc aaacaaaact
    72241 tgaacaacct ttctaaggtc ttgacctatg ctatcttggt cattgccctt gttacttttg
    72301 tagtgggtgt cttcattcaa gggaaaaatc cacttggtga gttgttgact tctgttgccc
    72361 ttgccgttgc agccattcca gaaggacttc ctgctatcgt taccatcgtt ctttctcttg
    72421 gtactcaagt tttggccaaa cgacattcca tcgttcgtaa gttgccagca gttgaaacac
    72481 ttggttcaac tgaaatcatc gcttctgata agactggtac gctgactatg aacaagatga
    72541 cagtcgaaaa agtcttctac gatgcggttc tacatgactc agctgatgat attgaactag
    72601 gtcttgaaat gccactactt cgttcagttc tcttggccaa tgatacgaaa atcgatgtgg
    72661 aaggtaactt gattggtgac ccaaccgaaa cagcctttat ccaatatgcc ttggacaagg
    72721 gctatgatgt caaaggtttc ttagagaaat atcctcgtgt agctgaattg ccatttgact
    72781 ctgaccgtaa gctcatgtca acagttcacc cattgccaga tggtcgtttc cttgtagcag
    72841 tcaagggtgc gccagaccaa ctcttaaaac gttgtcttct tcgtgataag gctagggata
    72901 ttgctccgat tgatgagaag gttacaaatc tcattcatac aaacaactct gaaatggctc
    72961 atcaagcctt gcgtgtcctt gcaggtgctt ataagattat tgacagcatt ccagaaaatc
    73021 tcacttctga agagcttgaa aatgatttaa tttttactgg tttgattggg atgattgacc
    73081 ctgaacgtcc tgaagccgct gaggctgttc gtgtggctaa ggaagcggga atccgtccaa
    73141 ttatgattac aggtgaccac caagacacag cggaagccat tgccaaacgt ttgggaatca
    73201 ttgacgcaaa cgatacagaa ggtcacattt taactggtgc tgaactcaat gaactgtcag
    73261 atgaagaatt tgaaaaagtc gttggtcaat actctgttta tgcccgtgtg tctccagaac
    73321 acaaggttcg tatcgtcaag gcttggcaaa aacaaggtaa agtcgttgcc atgacaggtg
    73381 acggtgtcaa tgacgcgcca gctctgaaaa cagccgatat cggtatcggt atgggaatca
    73441 ctggtacaga ggtttctaag ggggcttctg atatgattct tgcagatgat aactttgcga
    73501 ctattatcgt cgcagtggaa gaaggacgta aggtcttctc aaacattcaa aagactattc
    73561 agtacctact ttctgctaat actgctgaag tattaaccat cttcctatca accttgtttg
    73621 gttgggatgt cttacagccg gttcatcttt tgtggatcaa cttggtaacg gataccttcc
    73681 cagctatcgc tcttggtgtt gaacctgcgg aacctggtgt catgaatcat aaaccacgtg
    73741 gacgcaaggc aagcttcttc tcaggtggtg ttttgagttc tatcatttat caaggtgtac
    73801 tccaagcagc tcttgttatg agtgtttatg gccttgcgat tgcttaccca gttcatgtgg
    73861 gtgacaatca tgctattcat gcagatgccc taacgatggc ttttgcaacc cttggtttga
    73921 ttcagctctt ccatgcctac aatgtcaagt ctgtctacca atccatcttg acagttggcc
    73981 cattcaagtc taagaccttt aactggtcca tcttggtatc ctttatcctt ctcatggcaa
    74041 caatcgttgt agaaccgctt gaaggaatct tccacgtaac caaactagac ttgtcacaat
    74101 ggggaattgt tatggctgga agcttctcaa tgattatcat cgtcgaaatc gttaagttta
    74161 ttcaacgcaa actcggtttt gacaagaatg cgatttaagg gaggtttcgg atgtcagcat
    74221 attaattacc gaccgtatgg caggatgaag ctagtaatca aggagctttt acggggctaa
    74281 acagaccaac agtaggtgcc cgtttcgaac aaaacttgcc aaaaggagaa caagcttttc
    74341 agctttattc actgggaaca ccaaatggtg tgaaggttac tatcttattg gaagaattac
    74401 tagaagctgg ttttaaggaa gcggcttacg acttgtataa gattgctatc atggatgggg
    74461 atcaattcgg atcagacttt gtgaagctca atccaaattc caagattcca gccttattgg
    74521 accagtcagg tactgaagat gtaagagtct ttgagtctgc tcatattctt ctttaccttg
    74581 ctgagaaatt tggagccttt ttaccaagta atcctgtgga aaaggtagaa gttttgaatt
    74641 ggctattctg gcaagcaggt gcagcacctt ttctaggtgg gggatttgga catttcttca
    74701 attatgctcc tgaaaaattg gaatatccta ttaaccgttt tacaatggaa gtgaaacgcc
    74761 agttggattt attggataag gaattggctc agaaacctta tattgcaggc aatgactata
    74821 cgattgcaga tattgctatc tggtcttggt atggacagtt agttcaagga aatctttacc
    74881 aaggttctgc aaaattcttg gatgcctcaa gttatcaaaa tctagtaaaa tgggcagaaa
    74941 aaattgccaa tcgtccagct gttaagcgtg gcttggaagt aacttataca gaaattaaat
    75001 agcaaaaaag tcatcttcgg atggcttttt gctacagttg agggaaaggg tttgcagtta
    75061 tcggcttttg tgctataatt gctataataa tagtaaaaag caagaggagt gtgaggaagt
    75121 ggaaaagaaa attgtgaagg atatcttatt tttatctcaa gtgtctcagc cggcaagtca
    75181 ggaggacctt tatcttgcca gagatttgca ggatacactc ttagcaaatc gtgatacctg
    75241 tgttggtcta gctgccaata tgattggggt gcagaagcgc gtgattatct ttaatcttgg
    75301 cttggttccc gtggtcatgt ttaacccagt gcttctgtcc tttgaaggat cctatgaggc
    75361 agaagaaggc tgtttgtcct tggtaggtgt gagatcaact aagtgttatg aaaccataag
    75421 ggttgcctat cgtgacagca agtggcagga acagaccatt accttgacag gcttcccagc
    75481 tcagatttgc cagcatgagc tggatcactt ggaaggacga atcatttagg aggaaagcaa
    75541 atgaaacgaa tagtctttga acttattttt atcgcaacga cctggtatat ctttttaccg
    75601 ccccttaacc tgaccagctg ggaatttctc ttcttcctct gtgggcattt gttagttgtg
    75661 gcaatcttat ttggctttgg caaggggata aaccttgtca aaacggttca tgtgcgccac
    75721 ggtaaggcgg aagctgcctt aaatcttgag ggtttcaaaa tcaatcggtt agggaaaatt
    75781 ctgttagctt cgattggagg aattcttctc ttggcagctt tggtttcctt ggtaacttct
    75841 agcatgtttc aggctaaaaa ttatgccaat gtagtcacgg ttacggaaaa agactttact
    75901 gaatttccta agagtgacac cagtaaggtt cctatcctag atagaagtac tgctgaaaaa
    75961 attggagacc gctacttggg ttccctaacc gataaggtgt cgcaatacgt agcggcagat
    76021 acctataccc aattgacaat tgatgggaaa ccttatcggg tcacaccact agaatatgca
    76081 gaccctatca aatggtttaa caatcaagcc aagggaatcg gtgagtatat caaggtggac
    76141 atggtaactg gaaatgcgga tttggtggac ttgaagacac caatcaagta ttcagactcg
    76201 gagtatttta accgtgatgt caaacgtcac ctgcgcttga agtacccgac caaaatcttt
    76261 aaaactccat cttttgaggt ggacgatgag ggcaatcctt tctatgtagc aacggtttac
    76321 caaaagcaat ttggacttgc tgttcctcgt cctgcttcag tcattatctt ggatgctaca
    76381 aatggagaaa ccaaggaata cagcttatca gatgttccag aatgggtgga caggatctat
    76441 ccagcagagg aaaccattga gcaaattaac tacaacggca agtacaagga cggtttcttg
    76501 aatgccatga tttccaagaa aaacgtgacc cagactacca agggctataa ttacttgtct
    76561 atcggtaatg acatctatct ctacacaggt gtgacgtcgg ctaatgcgga tgagagtaat
    76621 cttggtttca tccttgaaaa tatgcgaaca ggagaaatca ctaagtatag cttggcttct
    76681 gcgacagaag aatcagcccg tgaatcagca gaaggtgctg ttcaggagaa atcctacaaa
    76741 gcaaccttcc caatcctcat caacctcaat gacaagcctc tctacatcat gggcttaaag
    76801 gacaatgctg gcttggtcaa agagtacgcc ctggtagacg cagtcgagta ccaaaatgtt
    76861 atcgttgcta ctacagtgga agagatgctc agcaagtatg ccaataaaaa cgaccttgaa
    76921 attgacaatg caacgacaga aagcatcaag ggagtagtag cagacctcaa atcagctgtt
    76981 atcaagggag acactgtcta cttctttaaa gttgatggca agatatacaa ggtcaaggct
    77041 tcagtatccg atgaccttcc ttaccttgaa aatggtaaaa ccttcgaagg tcaagtagga
    77101 aaagacaatt atctcaagac ctttaagcta cggtaaaaat aggttttttc agaaagtata
    77161 tgttataata gagtaaatta agactaatgg aggacaaaga aatgggtttt tatttgatgg
    77221 ttgcttcaat gctactcgga ctgctcgctt tgaagatagg tttttctcag ttcaaggaga
    77281 aaaaagataa attcttatct atcttaacaa gtttagctgg cacagccctt gttctcgtgg
    77341 ctgtctggtt aggatggccc aaataaatag aaaaacctcg gtcaaaccga ggtttttcaa
    77401 atgaatttct tggttgtggc taaaaaatat gctacactat caatatgaaa attttaatcc
    77461 caacagcaaa agaaatgaac acagacttgc caagtatcga ggcaattcct ttaaaaccag
    77521 aaagtcaggc cgtgcttgat gccttggctc tctattctgc cagtcaattg gagagtttct
    77581 acaaggtatc agctgagaaa gcggcggaag aatttcaaaa tatccaagct ttgaaaaggc
    77641 aaactgctca acactatcca gccttgaaac tttttgatgg gcttatgtac cgcaacatta
    77701 agagagataa gctgaccgag gcggaacaag attatcttga aaatcatgtc ttcattacct
    77761 cggctttgta cggtgttgtt ccagccttgt cacccatggc tcctcaccgt ttggattttt
    77821 tgatgaaatt aaaagtcgct ggtaagactt tgaagagcca ttggaaggca gtctatgatg
    77881 aagctctgaa gaaggaagaa gtgattttct ctctcttgtc atcagagttt gagactgtat
    77941 tttctaagga aatcagagca aagatggtga ccttcaaatt catggaggat agagggggtc
    78001 agctgaagat tcactcaact atctccaaga aggcgcgcgg ggcctttcta acagctttaa
    78061 tagaaaatca agtacaaact gtgggggaag cacgtcgctt gaactttgct ggatttgttt
    78121 accgagaaga tttgtcacaa ccacagggat tggtttttgt aaaggaagta tagaaatcag
    78181 atattttgta tttggcaata tgtatcatca gctattttag tttataaatg agaaaaaagc
    78241 gaacaagcta gtcttctgag tgtcagaaaa gtagtcttgt tcgcttttat tatgttatac
    78301 tcttcgaaaa tctaaaatct cttcaagcca cgtcagcgtc gccttaccgt atatatgtta
    78361 ctgacttcgt cagttctatc tacaacctca aagcagtgct ttgagtagct tgcggctagc
    78421 ttcctagttt gctctttgat tttcattgag tattagttta taaatgagaa aaaagcgaac
    78481 aagctaatct tctgagtgtc agaaaagcag tcttgttcgc ttttattatg ttagtttagt
    78541 tacttgatag cattgaccaa gtcttgagct tgtttgtcaa gtgagtttag gacagtttct
    78601 tcaagaacca atttcccgtc tgcccaggca gagtcattaa cacgtgcagc agtgaaatcg
    78661 ccaacgactt gtgtacggat aaatggcaag aggtctttgt agatagcgaa gagttgatcg
    78721 tgccctgcat tggctacaga tgatacggtg acaaacttgt cttgaagggc agaagcacca
    78781 cgtgtatcag acaagtcaag ggcacgagat agccagtcca gcaagttctt cactgtacca
    78841 gggatagaga agttgtagac tggagagaaa atccagatag catccgcaac gagaactgct
    78901 tcacgagcag cagctacagc tggatgtgtt ggaacttcca aatcttggct gaagagagga
    78961 agggctgaat aatcaaggta gctaacttcc gctttaccag caagtgcttt ctcagcttcg
    79021 agcgccattt ggtggttgaa agaaccttga cgtagtgatc cgacgataaa taatactttt
    79081 ttagacatga tgtgtctcct ttttcttcaa atttcgagaa ctctctcgtt gttataaaat
    79141 atattacaac aaaacaaaag aacttgcaag aaatttgctc agagtttatt tgaaaattgt
    79201 aaaatttcgg aaactctagt catttgtgac tgaaaaagta agaactgttt cactttcaaa
    79261 atcggttttg tttgaaggga gaaatagaat tggttgctca aagcacagct ttgaggttgc
    79321 agataaagct gacgtggttt gaagagattt tcgaagagta ttcttatatt cacttgtaat
    79381 aaagcttaat agatggtaaa atagacgagt gaaaaaaaga caaaacaaag caaaaaataa
    79441 tctactgtgg cagtatggtc tagggatgac gattttgttt gtggttatca gtgcttcctt
    79501 tctgtatatg gtttctctta gcatgaaacc ctatcaaaca gctaaaagtg aaggagaaaa
    79561 attagctcag cagtatgcag gattagagca ggccgatcag gttgatttat acaatggctt
    79621 ggaatcttat tacagcgttc ttggtcgtaa taaacagcaa gaagcacttg ctgttctgat
    79681 tggaaaagat gatcataaga tttacgttta tcagctaaat cagggtgttt cacaagaaaa
    79741 agcagaaacg gtttctaagg aaaagggagc tggcgaaatt gacaagatta tctttggtcg
    79801 ttatcaagat aagccaatct gggaagtcaa gtcaggatct gatttttatc tagtagattt
    79861 tgaaacagga gcattggtca acaaggaggg cctatgaaat tatccaaccg tgttttagaa
    79921 atggaagaaa gtgtgacttt ggctgctgga gcccgtgcca aagcactgaa ggctgagggc
    79981 agagatattt tgtctctaac cttgggtgag ccagatttca ctactcccaa aaatatccaa
    80041 gatgccgcca ttgcatcgat tcgagatggg cgtgcttctt tttatacagt aacctcaggt
    80101 ctgccagagc ttaaggcggc ggtcaatagc tactttgagc gcttttacgg ctattctgta
    80161 gcgtcaaatc aagtgacagt cgctgcggga gccaaatatt ctctctatac cttctttatg
    80221 gctgtggtca atccaggtga tgaagtcatc atcccaaccc catactgggt tagctatgga
    80281 gatcaggtca agatggcaga aggcgttccc gtctttgttt ctgctaagga agacaatcac
    80341 tttaaggtga ccgtggagca gttagaagca gctcgcactg acaagaccaa ggttttggtg
    80401 ctgaattcgc catctaatcc cacaggtatg atttacaccc gtgaggaact cttggcaatt
    80461 ggaaactggg ctgtagaaaa tgatattctc atcctagcag atgatatcta tggccgcttg
    80521 gtttataatg gtcatgagtt cacaccgatt tctagcctat cggaagcgat tcgcaagcaa
    80581 acagtggtca tcaatggtgt gtctaaaacc tatgccatga ctggttggcg gattggttat
    80641 gccgttggag aagcagacat tatcgctgcc atgtccaaga ttgcaggtca aacaacttcg
    80701 aatccgtcag cagtagccca atatgcagca gttgaggctc tatcaggtga gcaagatact
    80761 gtagaaagca tgcgtcaggc ctttgaggaa cgtcttaata ccatctatcc cctccttgca
    80821 gaggtgccag gatttgaagt ggtcaaacca caaggggcct tctatctctt cccaaatgtc
    80881 aaaaaggcca tggagatgaa aggctacacg gatgtgacag actttacaac tgttatctta
    80941 gaagaagccg aagtggcctt ggtaacagga gctggatttg gagcaccaga aaatgtccgc
    81001 ctcagctatg cgacagacct agacacgctt aaagaagcag tcgaacgctt gaaagcattt
    81061 atgggtagtg agaataattg atcattttga gattaaggta aaggatttac aaattttaga
    81121 aggattttat aggagttttc tcgctccttt ggactataaa ttggctttta agactagttc
    81181 tctaattagt tttctatccc cgaacagccc tcatcctggt ggtgattttt ggctgactca
    81241 gggaacacaa gatcctgttc attttgcttt tttagcagaa aataaggaag aagttcaggc
    81301 ttgttatgag gctggcttag aggcaggtgg gcgagacaat ggggctcctg gttatcgcag
    81361 tgagcatccg atttactatg ctgcttttat gattgacctg gatgggaaca atatagaggt
    81421 ggtttgccat aaagaataaa aaagaaaagg aaaaataatg acaaaacgtg taacgattat
    81481 tgacgtaaaa gactatgttg gtcaggaagt gacgattggc gcttgggttg ccaacaaatc
    81541 aggaaaaggg aaaatcgcct tcttacaatt gcgtgatgga acagccttct ttcaaggtgt
    81601 ggcttttaaa ccaaactttg tcgaaaaatt tggtgaagaa gtgggacttg agaagtttga
    81661 tgttatcaaa cgcttgagcc aagaaacgtc tgtttatgtg acaggtattg tcaaagagga
    81721 cgaacgttct aaatttggct atgagttgga catcacagac atcgaagtga tcggtgaatc
    81781 tcaagactac ccaatcacac caaaagaaca cggaacagac tttttgatgg ataaccgtca
    81841 cttgtggcta cgctctcgta agcaagtagc tgtgttgcaa atccgtaacg ctattatcta
    81901 tgcaacttat gagttctttg acaagaacgg ttttatgaag tttgacagcc caattctttc
    81961 aggaaatgcg gcagaagatt ctacagaact ctttgaaact gactacttcg gaacgccagc
    82021 ctacttgagc caatcaggtc agctttacct agaagcaggg gctatggctc ttggtcgtgt
    82081 ctttgacttt ggtccagttt ttcgtgctga aaaatcaaaa acacgccgtc acttgactga
    82141 gttctggatg atggatgctg agtactcata cttgacacat gatgagtcgc ttgacttgca
    82201 agaagcttat gtgaaagctc ttctacaagg tgttcttgac cgcgcgcctc aagccttgga
    82261 aaccttggaa cgtgatacag aactcttgaa acgctacatt gcagagccat tcaaacgtat
    82321 cacttatgat caagccattg acctcttgca agagcatgaa aatgatgaag acgctgatta
    82381 cgagcatctt gagcatggtg atgactttgg ttcgccacat gaaacttgga tctcaaatca
    82441 ctttggtgta ccaacttttg tcatgaacta tccagcagcc atcaaggcct tctacatgaa
    82501 accagttcct ggaaatccag agcgcgtgct ttgtgcagac ttgcttgctc cagaaggtta
    82561 cggagaaatc atcggtgggt ctatgcgtga ggaagactac gatgcccttg tcgctaagat
    82621 ggatgaactt ggcatggatc gtacagagta cgaattttac cttgaccttc gtaaatacgg
    82681 tacagttcca cacggtggat ttggtatcgg tatcgaacgt atggtaacct tcgcagcagg
    82741 aacaaaacac atccgtgaag ccattccatt cccacgtatg ttgcatcgta tcaaaccgta
    82801 agaataggaa aacgtccatg tggtgttttt tcgaattcca gagtttttac ttgcgtaaaa
    82861 aatttttttc tagtataata gttcattgtg agcgaacctc acttacccct tgcaaagtct
    82921 tggggtcatt agaccaaaag gaggaacata tcaatggcta aatacgaaat tctttatatc
    82981 attcgtccaa acattgaaga agaagctaaa aacgctttgg tagcacgttt tgactctatt
    83041 ttgactgaca acggtgcaac tgttgttgaa tcaaaaactt gggaaaaacg tcgtcttgca
    83101 tacgaaatca aagatttccg tgaaggactt taccacatcg ttaacgttga agcaaacgac
    83161 gacgtagctc ttaaagagtt tgaccgtctt tcaaaaatca acgctgacat tcttcgtcac
    83221 atgatcgtca aaattgacgc gtaagaaggt aaactatgat taacaatgtt gtacttgtgg
    83281 ggcgtatgac acgtgacgct gagttgcgtt ataccccatc aaatgtagca gttgcgactt
    83341 ttactcttgc agtaaaccgt acatttaaga gtcaaaatgg cgaacgtgag gctgatttta
    83401 tcaatgtcgt tatgtggcgc caacaggctg aaaaccttgc taattgggct aaaaaaggct
    83461 cacttatcgg ggtgacaggc cgtatccaga ctcgtagtta cgataaccag caaggacaac
    83521 gtgtctacgt gacagaggtc gtggctgaga atttccaaat gttggaaagc cgtagtgtgc
    83581 gtgaaggtca cacagttggt gcctattctg caccaactgc aaactattca gcgcctacaa
    83641 attcagtacc agacttttca cgtgatgaaa atccatttgg agcaactaat ccattggata
    83701 tttcagatga tgatttacca ttctaatgga caactaaaat tataaaggag aaaaaacatg
    83761 gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag ttgattacat cgcagcaaac
    83821 aaaattgaat atgttgatta caaagatact gagcttctta gccgtttcgt ttcagaacgt
    83881 gggaaaatcc ttcctcgtcg tgtaacagga acttcagcta aaaaccaacg taaagtaaca
    83941 acagctatca aacgcgctcg cgtaatggct ttgatgcctt tcgtaaacga agattaaaga
    84001 aaagaggctc tttgtcaact gtagtgggtt gaagtcag
//
LOCUS       DAVDHZ010000006        66738 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000006 DAVDHZ010000000
VERSION     DAVDHZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.006"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(84..1244)
                     /locus_tag="VUR46_000508"
     CDS             complement(84..1244)
                     /locus_tag="VUR46_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5455996.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(1345..1593)
                     /locus_tag="VUR46_000509"
     CDS             complement(1345..1593)
                     /locus_tag="VUR46_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET5455997.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VUR46_000510"
     CDS             complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VUR46_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET5455998.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VUR46_000511"
     CDS             complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VUR46_000511"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET5455999.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3154..3621)
                     /locus_tag="VUR46_000512"
     CDS             complement(3154..3621)
                     /locus_tag="VUR46_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET5456000.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMNDYAQYLYQEKGTELTHLPFETVQTALKEADLM"
     gene            complement(3640..4197)
                     /locus_tag="VUR46_000513"
     CDS             complement(3640..4197)
                     /locus_tag="VUR46_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET5456001.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            4322..5167
                     /locus_tag="VUR46_000514"
     CDS             4322..5167
                     /locus_tag="VUR46_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5456002.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            5226..6395
                     /locus_tag="VUR46_000515"
     CDS             5226..6395
                     /locus_tag="VUR46_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET5456003.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVLDINAHTGGFNITSALCTGWVAGSLH"
     gene            6421..6876
                     /locus_tag="VUR46_000516"
     CDS             6421..6876
                     /locus_tag="VUR46_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET5456004.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEELSEFFYYKNGDDWLYDLK"
     gene            6985..8275
                     /locus_tag="VUR46_000517"
                     /pseudo
     CDS             6985..8275
                     /locus_tag="VUR46_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937360.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(8415..9164)
                     /locus_tag="VUR46_000518"
     CDS             complement(8415..9164)
                     /locus_tag="VUR46_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET5456005.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            9269..9490
                     /locus_tag="VUR46_000519"
     CDS             9269..9490
                     /locus_tag="VUR46_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HET5456006.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGWPSGLVPFGSFPT"
     gene            9487..10738
                     /locus_tag="VUR46_000520"
                     /pseudo
     CDS             9487..10738
                     /locus_tag="VUR46_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(10760..11704)
                     /gene="manA"
                     /locus_tag="VUR46_000521"
     CDS             complement(10760..11704)
                     /gene="manA"
                     /locus_tag="VUR46_000521"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET5456007.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDTLLTKVPVKAG
                     DFFYVPSGTMHAIGPGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLFSILAGQGQL
                     TVDGKNYPIQKGSHFIVLSDVESWTLEGQDLELIVSHP"
     gene            complement(11825..12122)
                     /locus_tag="VUR46_000522"
                     /pseudo
     CDS             complement(11825..12122)
                     /locus_tag="VUR46_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380709.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            12187..13294
                     /locus_tag="VUR46_000523"
                     /pseudo
     CDS             12187..13294
                     /locus_tag="VUR46_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(13411..13758)
                     /locus_tag="VUR46_000524"
     CDS             complement(13411..13758)
                     /locus_tag="VUR46_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5456008.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVK
                     GPAGLVLDFYRMK"
     gene            complement(13869..15644)
                     /gene="spxB"
                     /locus_tag="VUR46_000525"
     CDS             complement(13869..15644)
                     /gene="spxB"
                     /locus_tag="VUR46_000525"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET5456009.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(15851..18094)
                     /locus_tag="VUR46_000526"
     CDS             complement(15851..18094)
                     /locus_tag="VUR46_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET5456010.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEAIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDETEVLGLATSLEEASQHPLAEAIVKRASEAGLEFHTVENFQALHGKGV
                     SGQINGKQVLLGNAKMLDGMDISSIYQEKLEQLEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLKTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKVHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(18104..18475)
                     /locus_tag="VUR46_000527"
     CDS             complement(18104..18475)
                     /locus_tag="VUR46_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET5456011.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYAPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(18486..18881)
                     /locus_tag="VUR46_000528"
     CDS             complement(18486..18881)
                     /locus_tag="VUR46_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET5456012.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      19065..19163
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            19247..20038
                     /gene="thiD"
                     /locus_tag="VUR46_000529"
     CDS             19247..20038
                     /gene="thiD"
                     /locus_tag="VUR46_000529"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET5456013.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDTPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(20247..20879)
                     /locus_tag="VUR46_000530"
     CDS             complement(20247..20879)
                     /locus_tag="VUR46_000530"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET5456014.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(20872..21675)
                     /locus_tag="VUR46_000531"
     CDS             complement(20872..21675)
                     /locus_tag="VUR46_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET5456015.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(21675..22199)
                     /gene="thiW"
                     /locus_tag="VUR46_000532"
     CDS             complement(21675..22199)
                     /gene="thiW"
                     /locus_tag="VUR46_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET5456016.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(22204..22896)
                     /gene="tenA"
                     /locus_tag="VUR46_000533"
     CDS             complement(22204..22896)
                     /gene="tenA"
                     /locus_tag="VUR46_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET5456017.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKVFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(22907..23557)
                     /locus_tag="VUR46_000534"
     CDS             complement(22907..23557)
                     /locus_tag="VUR46_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET5456018.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRIFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(23559..24944)
                     /locus_tag="VUR46_000535"
     CDS             complement(23559..24944)
                     /locus_tag="VUR46_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456019.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELMFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAAMAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRELTSIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(24945..25505)
                     /locus_tag="VUR46_000536"
     CDS             complement(24945..25505)
                     /locus_tag="VUR46_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5456020.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNIFSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(25766..25854)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(26063..26692)
                     /locus_tag="VUR46_000537"
     CDS             complement(26063..26692)
                     /locus_tag="VUR46_000537"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET5456021.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKYDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(26694..27476)
                     /gene="thiM"
                     /locus_tag="VUR46_000538"
     CDS             complement(26694..27476)
                     /gene="thiM"
                     /locus_tag="VUR46_000538"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET5456022.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(27719..28387)
                     /locus_tag="VUR46_000539"
     CDS             complement(27719..28387)
                     /locus_tag="VUR46_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET5456023.1"
                     /translation="METQDYAFQPGLTVEELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(28602..28690)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(28944..30080)
                     /gene="lctO"
                     /locus_tag="VUR46_000540"
     CDS             complement(28944..30080)
                     /gene="lctO"
                     /locus_tag="VUR46_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET5456024.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(30704..32194)
                     /gene="lysS"
                     /locus_tag="VUR46_000541"
     CDS             complement(30704..32194)
                     /gene="lysS"
                     /locus_tag="VUR46_000541"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET5456025.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            32379..32759
                     /locus_tag="VUR46_000542"
                     /pseudo
     CDS             32379..32759
                     /locus_tag="VUR46_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(32846..33493)
                     /locus_tag="VUR46_000543"
     CDS             complement(32846..33493)
                     /locus_tag="VUR46_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456026.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(33490..34188)
                     /locus_tag="VUR46_000544"
     CDS             complement(33490..34188)
                     /locus_tag="VUR46_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456027.1"
                     /translation="MGKLSSHMWRLNQIIYAKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLVVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(34198..34950)
                     /locus_tag="VUR46_000545"
     CDS             complement(34198..34950)
                     /locus_tag="VUR46_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456028.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFHLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(34950..35752)
                     /locus_tag="VUR46_000546"
                     /pseudo
     CDS             complement(34950..35752)
                     /locus_tag="VUR46_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35848..36251)
                     /locus_tag="VUR46_000547"
                     /pseudo
     CDS             complement(35848..36251)
                     /locus_tag="VUR46_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36431..37063)
                     /locus_tag="VUR46_000548"
     CDS             complement(36431..37063)
                     /locus_tag="VUR46_000548"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET5456029.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(37097..37798)
                     /gene="pyrF"
                     /locus_tag="VUR46_000549"
     CDS             complement(37097..37798)
                     /gene="pyrF"
                     /locus_tag="VUR46_000549"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET5456030.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            38117..38209
                     /locus_tag="VUR46_000550"
                     /pseudo
     CDS             38117..38209
                     /locus_tag="VUR46_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(38532..39245)
                     /locus_tag="VUR46_000551"
     CDS             complement(38532..39245)
                     /locus_tag="VUR46_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456031.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEEFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(39238..40071)
                     /locus_tag="VUR46_000552"
     CDS             complement(39238..40071)
                     /locus_tag="VUR46_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456032.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
     gene            complement(40281..41429)
                     /locus_tag="VUR46_000553"
     CDS             complement(40281..41429)
                     /locus_tag="VUR46_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET5456033.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISI
                     KVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILF
                     LLVNFRTFIQLPVDIFISMIIFLMLWIFIMLGIVCLSYYITLLFSKEA"
     gene            complement(41466..41654)
                     /locus_tag="VUR46_000554"
                     /pseudo
     CDS             complement(41466..41654)
                     /locus_tag="VUR46_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(41638..42645)
                     /locus_tag="VUR46_000555"
     CDS             complement(41638..42645)
                     /locus_tag="VUR46_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HET5456034.1"
                     /translation="MRIVDKIKILPTPYEGQYHLYIPSSKKHVLVGKQEKKWLEQLIG
                     QEFTISDLLVLVGKKYYLRFYIVLSKMGLIDSMKSRKKINIFKISWDFNITLSEKLNY
                     KRFNKNFEKILFGIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISA
                     TIHEFSHAIIANNYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIAS
                     NSILSLTGLLVLLFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNL
                     NFQYIVQLLIAFVIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLR
                     K"
     gene            complement(43227..44465)
                     /gene="divIB"
                     /locus_tag="VUR46_000556"
     CDS             complement(43227..44465)
                     /gene="divIB"
                     /locus_tag="VUR46_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET5456035.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKVASSE
                     ADKEKEEKEEPESKEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIV
                     SAYLLSPYATMKDIRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYW
                     VESAQLVYQFPTKFTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLS
                     VLFNDSEQIKVFVSELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSE
                     MSKKLPYYSKIKPQLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEE
                     QKKQEEESNRNQTTQRSSRR"
     gene            complement(44475..45533)
                     /locus_tag="VUR46_000557"
     CDS             complement(44475..45533)
                     /locus_tag="VUR46_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET5456036.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(45537..46889)
                     /locus_tag="VUR46_000558"
     CDS             complement(45537..46889)
                     /locus_tag="VUR46_000558"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET5456037.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGTIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAVNEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(46993..47634)
                     /locus_tag="VUR46_000559"
     CDS             complement(46993..47634)
                     /locus_tag="VUR46_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456038.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(47636..49657)
                     /locus_tag="VUR46_000560"
                     /pseudo
     CDS             complement(47636..49657)
                     /locus_tag="VUR46_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(49740..50039)
                     /locus_tag="VUR46_000561"
     CDS             complement(49740..50039)
                     /locus_tag="VUR46_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET5456039.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASTAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(50402..50656)
                     /locus_tag="VUR46_000562"
     CDS             complement(50402..50656)
                     /locus_tag="VUR46_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET5456040.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(50676..52517)
                     /gene="typA"
                     /locus_tag="VUR46_000563"
     CDS             complement(50676..52517)
                     /gene="typA"
                     /locus_tag="VUR46_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET5456041.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPIDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            52679..53404
                     /locus_tag="VUR46_000564"
     CDS             52679..53404
                     /locus_tag="VUR46_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HET5456042.1"
                     /translation="MRLDNLLAQEKISRKAMKQALFKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(53444..53671)
                     /locus_tag="VUR46_000565"
     CDS             complement(53444..53671)
                     /locus_tag="VUR46_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456043.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(53760..54140)
                     /locus_tag="VUR46_000566"
     CDS             complement(53760..54140)
                     /locus_tag="VUR46_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5456044.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(54140..54409)
                     /locus_tag="VUR46_000567"
     CDS             complement(54140..54409)
                     /locus_tag="VUR46_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET5456045.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            54473..55381
                     /locus_tag="VUR46_000568"
     CDS             54473..55381
                     /locus_tag="VUR46_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET5456046.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(55435..56190)
                     /locus_tag="VUR46_000569"
     CDS             complement(55435..56190)
                     /locus_tag="VUR46_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET5456047.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(56211..57140)
                     /locus_tag="VUR46_000570"
     CDS             complement(56211..57140)
                     /locus_tag="VUR46_000570"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET5456048.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCAGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(57155..57778)
                     /locus_tag="VUR46_000571"
     CDS             complement(57155..57778)
                     /locus_tag="VUR46_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET5456049.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(57771..59009)
                     /gene="hflX"
                     /locus_tag="VUR46_000572"
     CDS             complement(57771..59009)
                     /gene="hflX"
                     /locus_tag="VUR46_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET5456050.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(59002..59886)
                     /gene="miaA"
                     /locus_tag="VUR46_000573"
     CDS             complement(59002..59886)
                     /gene="miaA"
                     /locus_tag="VUR46_000573"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET5456051.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSETKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            60007..60177
                     /locus_tag="VUR46_000574"
     CDS             60007..60177
                     /locus_tag="VUR46_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET5456052.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(60225..61064)
                     /locus_tag="VUR46_000575"
     CDS             complement(60225..61064)
                     /locus_tag="VUR46_000575"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET5456053.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLIQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(61161..62120)
                     /locus_tag="VUR46_000576"
     CDS             complement(61161..62120)
                     /locus_tag="VUR46_000576"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET5456054.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(62247..63245)
                     /locus_tag="VUR46_000577"
     CDS             complement(62247..63245)
                     /locus_tag="VUR46_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5456055.1"
                     /translation="MNKRLFLKMSLATLPVLALFSQPVLAEENIHFSSCKEAWGNGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTATQINTSSATTSGWVKQDGA
                     WYYFDGNGNPVKNAWQGSYYLKADGKMAQSEWVYDSSYQAWYYLKSDGSYAYSTWQGN
                     YYLKSDGKMAQSEWAYDSSYQAWYYLKSDGSYAYSTWQGNYYLKSDGKMAKGEWIYDS
                     SYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGDDGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(63295..63912)
                     /locus_tag="VUR46_000578"
     CDS             complement(63295..63912)
                     /locus_tag="VUR46_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5456056.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSSYQKA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALVLSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMIGVSEELKTLDLTDIAGICPYPTLLICGSKDRPNL
                     SSMKTLHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKIRSFLELLK"
     gene            complement(63913..65634)
                     /gene="pabB"
                     /locus_tag="VUR46_000579"
     CDS             complement(63913..65634)
                     /gene="pabB"
                     /locus_tag="VUR46_000579"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET5456057.1"
                     /translation="MHRKTVIDFRALGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     KQGYYVVGYVSYEAAPAFEEKFAVHKAPLLGEYLLYFTVHDSVETSPIPLTYDEVDLP
                     SDWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVIEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNGRELATRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVEHLCQVEQYSTVWQMTSTIKSRLRADVDLI
                     TIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYQEVHQKAAVLYRKQARFQLITTGKISQKNLLFEA
                     QHLERLRKASRYFASPFDAEDLKQKIKEECQDCDVNQDYRLRISLSKSGEIEVNRQVL
                     TPLSRTFCYAQLCLQEANLQQAFTYFKTSHRPHLGLRKQEIIYHNAAGELLETSIGNL
                     VLKISGRLYTPPIELGILPGIYRQHLLERGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELILQEN"
     gene            65821..>66738
                     /locus_tag="VUR46_000580"
     CDS             65821..>66738
                     /locus_tag="VUR46_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5456058.1"
                     /translation="MEQLHFITKLLDIKDPNIQFMDIINMDTHKEIIAKLDYDAPSCP
                     NCGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKASMTDIAHQLSISTSTVIRKLNDFRFKHDFSYLPEIMSWDEYS
                     FTKGKMSFIAQDFKKLNIIAVLEGRTQAIIRNHFLRYDRAIRCQVKIITMDMFSPYYA
                     LAKQIFPCAKIVLDRFHIVQHLSRAMSRVRVQIMKQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLTYS"
BASE COUNT        20199 a        14320 c        12027 g        20192 t
ORIGIN      
        1 agtttgaaga gattttcgaa gagtattaaa tatcgaaaca gggagtgagt caaaggctca
       61 ttccctattt caacattttt ctattatggt tttacaactt ctgctgcttc aactttacca
      121 ttgttcatgg tcatcatgta agcagttttg actgtgttgt ggtctgcatc gaagcttgtt
      181 tgaccagtta caccttcaaa atcttttgtt ttagcaaggt tatccttgat ttcacctgaa
      241 tttttagcac cttttgctgc gtttgctaca aggtgaactg aatcataagc caaggctgca
      301 aatgttgaag gctcttcatt gtacttagca cggtaagcgt caaggaaggc tttagcttta
      361 gctgaaactt ctacagtagt tgagaagcct gagataaagt agatgtttga tgctttttca
      421 gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat caccaccaac gattggtttg
      481 tcaattccca tgccacgcgc ttggtttaca atcttaccag cctcattata gtaaccagga
      541 acaacgatag catcaaagtc tttccctttc atttttgtaa gggctgcttg gaagtctgtg
      601 tcacctgcta cgaaagtttc atctgcaacg atttcaccct tgtatgactc gcggaaagat
      661 ttagcaatcc ctttagcata gtcactggca ttgtcagtgt aaagaacaac tttcttagca
      721 tttaattttt cagaaacata gtttgagata atttttcctt ggaagctatc ttggaaagtt
      781 ccaataaaga ggtaatcttg acctttagtc aatccatctt gagtcgcact tggtgagatc
      841 aatggaacac ctgcttttgt agcgttcgct accgcagctg cagtcgcacc agatgtcgca
      901 ggtcctacga ctgctgatac tttagattgg gttacaaggt tagttgtaac tgaagcagcc
      961 tcagctgttt cagacttatt atctttatcg actacttcga tttgttttcc atcgatacca
     1021 cctgcggcat tgatttcatc aacagccaat tgggcacctt tttgttcagc tgttccgtat
     1081 gcagctaaag aacctgattc ttcaaagtta aacccgattt taattgtctt ttcctctact
     1141 gagttaccag cagtgttgac tgctccagac ttcacttctc cacaggctgc aagaagtgct
     1201 acacttgcaa gcgccacaaa cgatagggca aattttttct tcatcttttt gtctccttat
     1261 ttcttaaata gtctgttaag aatataccga attatcagaa aattgtcaat gttttccttg
     1321 aactttttct atgataacgt tttcctatcg ataaagattg cccacaaagg gtgtttccaa
     1381 ctcttggata tgacaaaccc taactttttt aataaatttt tccttgctca agcgtccgac
     1441 caattgctcc acttcttgag ttggaacata gagttgtaag taacgatgtt tcttggaatg
     1501 ataggtaata tctccataat cctgcagttt tttggcatca cgattatagt aaagatagat
     1561 aatcaagcca gagcgattga ctttttcaaa catgataaat cctctttcta agaaatctct
     1621 ccctattata ccaaaaaaag caaacccagt cgagtttgcc ttctatcatc attagttcaa
     1681 tgaattgttg gccataattt catcaataaa gccatattca agtgtttcct gggcgctcat
     1741 ccagttatca cgttctgcat ctgcatggac tttttccatt gactgacctg aattttcagc
     1801 caagattttt tccaaggtat tacgagtttt gagcaagtgt tctgcagcga tagccatatc
     1861 agtttgttgg gtaccaccac ctgtaccgcc cattggttgg tgaatcatgt attcagcatt
     1921 tggaagcatg aaacgtttgc cttttgctcc acttgatgcg atgactgttc ccatagatgc
     1981 agccattccc ataacaatgg tttggacatc tgccttgata aagttcatgg tatctacgat
     2041 tgccaaacca gctgaaacag aaccacctgg tgtattgaca taaaggtaaa tatcttttgt
     2101 actatcttgg gcatccaaga aaagcaattg ggcaataaca gagttagcca tattgtcttc
     2161 aaccggacct gtcagcataa tgatgcggtc tttgagaaga cgtgagtaaa tatcgtaaga
     2221 acgttctcca cggcttgttt gttcaataac tacaggaatc attcatttct ccttttgagt
     2281 tttaattttg ttggtcaaat gactgaagat aagactatta taatatcttg gtcaaaaaag
     2341 gtcaaatttt tgctctgctt tcattagaca gaaacaaaaa cccaacctcc tttcgtgact
     2401 ggaaatactt ttccaagtca ttcttctttt cgatcttatt ttgtaccgaa caagcggtct
     2461 ccagcatctc caagacctgg aacgatataa ccgtgttcgt tcaaacgttc atccaaggct
     2521 gctgtaaaga tttctacatc tggatgagct tcttgaaggg cttttacacc ctctggagca
     2581 gatacaaggc agacaaattt gatatttgat gcgccacgtt ttttaagaga atcaacagcc
     2641 aagattgctg agccacctgt tgccaacatt gggtctacta caaaaatttg acgttggtca
     2701 atgtcctcag gcaatttcac caagtattca actggttgaa gtgtttcttc atcacggtac
     2761 ataccgatgt ggccaacttt agcagctgga accaagctca agagaccatc aaccatcccg
     2821 atacctgcac gcaagattgg gacgatggcc aatttcttac ctgccaattg tttttgaact
     2881 gtttttgtaa ttggtgtttc gatttccaca tcttctagtg gaagatcacg aagtacttca
     2941 taccccatca acattgcaat ctcatctact agctcacgaa aagcttttgt agaagtatct
     3001 gtacgacgca agattgacaa tttgtgttga atcagtgggt gattaataac ttcaattttt
     3061 cccatttttg gaattccttc tttcaattta ttcttctcat tataccaaaa aacggtttaa
     3121 aaatctttct aaaccattta tttttgataa tttttacatt agatcagcct ctttaagagc
     3181 tgtctgtact gtctcaaatg gtaaatgggt caattctgtc cctttttctt gataaaggta
     3241 ttgggcgtag tcgttcattc ggtactggtt gatataaacc acgcgcttgc agccgacctg
     3301 aagcaattgt tttgtacagt tgagacaagg aaaatgggtt acataggctg taaatccttt
     3361 gggaacacca cgctcagcac cttgaaggat agcattgacc tcagcgtgaa gggtgcgaac
     3421 acagtggcct tcaatgacca aacattcgtg atcaatacaa tgctcagtcc ctgacaccga
     3481 accattgtaa ccagtggaaa taaccttatt atcttttacc agaatcgcgc ccactttagc
     3541 acgtttacaa gtggaacgat tcgcaattag tagggcttgg gctgcaaaat actcatccca
     3601 tgccagtctt ttttcagtca tctcttttct cctttttctc tattttttaa aaaatggtaa
     3661 acctaaatct gcaatctttt cagctggtac cttcatgcca tccttgatcc attttagaag
     3721 gacagagacg atggctgagc tccagaagga atgaagataa gagctgacac cttttgattt
     3781 cccatggtat ttttctagaa attcctgcat ggcttggaca aagatttttt ccagatggta
     3841 atccaaggcc aattgaatta ctctagcttc ctttctggcc tcccggaaaa ggtgaaccca
     3901 aaccaaataa aggtctgtct ttaaatcgta atgatgcagc tgttccataa tattgtggac
     3961 agttcgttta aagacgctct ctaaaatttc ctctttggag tcataattgc gataaaaggc
     4021 cgcacgcgaa acacctgcac gtttgaccaa ttcagaaata ctaatcttgg tcagctcctt
     4081 tttttccaag agttgcaaga gggctgtttc aatggcttct ctggttaata aattggattc
     4141 ttggtttgat tttctgagat tttcaagaga cttttcagag attctacgtt cagacataac
     4201 attttctttc tacttgtcac aacagacgga tgatgctttt gtttcaaggg ttttcatgat
     4261 ataattgtaa aaaaagacag aacctttgtc aatgtataac tgacaaagat ggagaatttc
     4321 tatgacttgg aagattattg ctgactctgg ttgtgattat cgtcaactgc caacaccagc
     4381 tattaacaca acctttgtaa gtgtcccctt aaccattcaa gtagctgatc aggtctttgt
     4441 tgatgacgcc agtctcgata ttgaccaaat gatggaaacc atgtatgcaa ctgcagaagc
     4501 ttcaaaatcg gcttgtccaa gcccagatga ctatttgcga gcatttgaag gtgccaaaaa
     4561 cattttccta gtaaccatca caggtaccct ttctggcagt cacaatagtg ctcaactagc
     4621 aaagaatatt tatctggaag accatcctga cactaagatt catgtgattg atagtttatc
     4681 tgctggtggt gaagttgacc tactcgtaga aaaattgaat gacttgattg accagggctt
     4741 gtcttttgaa gaagtggttg aagctatcac cgcctatcaa gaaaaaacta agttgctctt
     4801 tgtcctagcc aaagtcgata acttggtgaa gaacggccgt ttgagcaagc ttatcggtac
     4861 ggtcgttggc cttctcaaca ttcgtatggt cggaaaagct agtgaaactg gaactctcga
     4921 attgctacaa aaagcaaggg gatcaaagaa atcagttcaa gctgcctatg atgagttagt
     4981 aaaagctgga tatgctggtg gccgtattgt catggcccaa cgcaataacg aaaaatgttg
     5041 tcaacagctc tcagagcgaa tccgtgaaac cttcccacaa gcggatatta aaattctacc
     5101 aacctctggt ctctgcagtt tctatgcaga agagggcggt ttgctgatgg gctatgaaat
     5161 tgattaattg cattcttgac aagaggtgac catcatctct tgtttttttg tggtacaata
     5221 gagctatgaa acattttgat actattgtca tcggtggggg acctgctggt atgatggcta
     5281 cgatttccag tagcttttat ggacagaaaa ccctcctcat cgaaaaaaat cggaaacttg
     5341 gaaaaaaatt agctgggact ggtgggggac gttgcaatgt gaccaacaat ggtagcttag
     5401 acaacctgct agctggaatt cctggaaacg gacgctttct ttacagtgtt ttctcccagt
     5461 tcgataatca tgacatcatc aactttttta cagaaaatgg tgttaaactt aaggtcgaag
     5521 accacggacg cgtctttcca gccagtgaca agtctcggac tattatcgaa gctttggaaa
     5581 agaaaatcac tgaactaggt ggtcaagttg ctactcaaat agaaatcgtt tctgttaaaa
     5641 aagtagatga ccagtttgtc cttaagtcag cggatcaaac cttcacttgt gagaaactca
     5701 ttgtcacaac aggtggtaag tcttatcctt cgactggttc gactggtttt ggtcacgaga
     5761 ttgctcgcca ttttaagcat accatcaccg agcttgaggc tgctgaaagt cctttattaa
     5821 cagattttcc acataaagcc ttacaaggga tttctctgga cgatgtgacc ctaagttatg
     5881 gtaagcatgt catcactcat gatttactct ttacccactt tggtttgtca ggtcctgctg
     5941 ccctacgcat gtctagcttt gtcaaaggtg gggaggttct ctcactcgat gttttgcctc
     6001 aactttctga gaaggacttg gttacatttc tagaagaaaa tcgggaaaaa tccttgaaaa
     6061 acgctttaaa aaccttgtta ccagaacgct tggccgaatt ttttgtacaa ggatatcctg
     6121 aaaaagtcaa acagctgact gaaaaggaac gagaacaact tgtccagtcc attaaagaac
     6181 ttaaaattcc tgtaactgga aaaatgtccc ttgcaaagtc ctttgttacc aagggtggag
     6241 tcagtctcaa ggaaatcaat cctaaaactc tggaaagcaa actcgttcct gggctccact
     6301 ttgctggcga ggtactggat atcaatgccc acacgggcgg ctttaacatt acttctgccc
     6361 tctgtaccgg atgggtggcg ggaagtctgc attaagatta aagattaaag gttgtgaaga
     6421 atgaacagaa gagaggcagt cgaatttgtt aacatgtgta tgattaaaaa cggagataag
     6481 gtcctggtcc aagaccgagt tagtcccgac tggcctggca ttacttttcc tggtggtcat
     6541 gttgaacgtg gcgaatcctt tgtcgatgct gtcattcgtg aagtgaaaga agaaactggt
     6601 ctgatcattt ccaaacccca actctgtggt atcaaaaact ggtatgacga caaggattat
     6661 cgttatgtcg tcctttttta caagacagaa cactttactg gtgaactcca gtcttcagac
     6721 gaagggaaag tttggtggga ggactttgaa aatctttctc atctaaaact tgcaaccgat
     6781 gatatgtctg atatgcttcg tgtgtttcta gaagaagaac tcagtgaatt cttttactac
     6841 aaaaacggtg acgactggct ttatgatttg aagtaaaaaa taggctagga aattcccaat
     6901 gtcattaagt taagaaattc aaatacaatt ctgtatttgg gtctcttttt tatgtgataa
     6961 actatagtta aggaggtatt tcccatgata aaacagataa aagcccactt gaataagagt
     7021 attcagagta tcattggcca aaaagttgag ttcgtcaaac aagatgaaca gacctttact
     7081 cgtaaaagaa ggttatcact agaaactatg attcgtacaa ttctgggcat gggaggaaaa
     7141 tcactatcaa aagaattact agatgccaga ctgacagttt caaattcagc ctttgttcaa
     7201 agacgctatc agataaaacc tgaagctttc tatgccctat ttaaagaatt tacagcacct
     7261 attccactta atactgattt tccaatattc gctgcagatg ggagtgatat ctgtattcct
     7321 cgaaatccca tggatacaga aacctctatc caaacccaaa cggatgttaa atcctataat
     7381 ctcatacaca taaatgccct atacgacttg acgactggag tgtatagaga tgtctctatt
     7441 caagacaaac atgcacaaca tgagcgctta gctctgattc agatgacgga ggcttctccc
     7501 tttcgagaaa gctcttgtta tcatggatag aggctatgaa agttacaatc tcatggctca
     7561 ttttcaagaa aaaggttggc tttatatcat ccgtattcga gatggaaaac aatccatgcc
     7621 ttcctccttc aacttgccaa atacggagtg ttttgatcaa aaagtttctc taaaattatc
     7681 acgaaagcaa accaatcagc tcaaaaaact ttatcgtgat tttcccaatg actatcattt
     7741 tattccacac aattctattt ttgattttct tccagaaaca agtcgaaaac aagatcctgt
     7801 aacactctat gaacttcctt ttcgtatggt gcgtttagaa gtggaagaag gaaaatacga
     7861 aactttagtg acgaatacag actattcagt ccaagaatta aaaaatctct acgccagtag
     7921 atggggcata gagactagtt ttcgtgacct gaaatacagt attggcttgg tcaattttca
     7981 cgccaaaaag aaggaaggga ttctccaaga aatctttgct cgctttacaa attttaactt
     8041 ttgtcgttgg gtaaccttgc aagttgccat cgacagtagt cacaaaaaac aaagatataa
     8101 agtgtgtttc tcagatgcgg cttatgcctg ccgtttgttt tttaacggtt ccctttcttc
     8161 cctccagttg aaaaactacc tcaagaaaca gttatctatt attcgaccga atcgaaaata
     8221 ttcaagaaag ataaaagctc aatcggtagt tgatttcatc tatagagtaa cataaatctc
     8281 aaaaaatagg gtgaaaaaac ctttatttgt catgcaaaaa aatagaagat gtgatagaga
     8341 atcactttga tgatcccaat cacacctcct attcaagtag ttagatcact aacttaatga
     8401 cattgaggaa attcctagcc tattttttct gcatttgtct gaacgtaagc tgcaatggca
     8461 tctgacgtgt actgggctgt tccagaacca aacttgtcaa tgttttcctt aaactctggg
     8521 ttgtagacgt aacctttacc gatatgaccg aatacctcaa tagagcagtc aaatccataa
     8581 gtgcgaatgg cttgcaagag cttggctgct tgctcttggt tttcggttgc tgttgcaggt
     8641 aaaccaactt gaagattttg tgccaaagtt tgaaagactt ggttaaaggc ggccgtagcc
     8701 tcgtcttcgt gacctttttg gcgttcgagc gcttgtccca tgacttcttg accatatttc
     8761 tctaccgctt cttggtggta tttttgattg tcttgatagc taaatcccgt gaatttttcc
     8821 tcaatggtca tttttctttc tcctttttgt tcttgaatag ttttttgcaa ggtggaaatc
     8881 aaggtatcca gatgttgcct ttcgcgagtt agatagtcca actgcctagt caaatggggc
     8941 aataaatctg tcctttcttc ctttaacagc tctgctattt tctctaaaga aaagcctaga
     9001 tatttgtagt aaagaatgac ctgaaggcgt tccaaatcct cttgactgta ggttcgatag
     9061 ccgttttccg actttaaggg gaccaagagt cctatcttgt catagtgatg cagggtcttg
     9121 acagagacac ctgaaagctg cgcagcttct tttatatggt acatgatttc ctccttacaa
     9181 tgatagtata acccctcccc ttaggtcaga gtcaagcgtt tttgagaaaa ttttttaact
     9241 tttttgagaa aggtgtgaaa acttgaaaat gattttcttg acagacctta gaaaacatga
     9301 taggatagtc aagtctatca atcaaacaga aggctatttg acaactcaag tagctttttc
     9361 ttattttgaa aaaggagatc agagtttaac tatgtcagaa aaatcacaat gggggtcgaa
     9421 acttggtttt attctagcat ctgctggctg gccatcgggc ttggttccgt ttggaagttt
     9481 ccctacatga ctgctgctaa tggcggtgga ggctttttac taatctttct catttccact
     9541 attttaatcg gtttccctct cctgctggct gagtttgccc ttggccgtag tgctggcgtt
     9601 tccgctatca aaacctttgg aaaactgggc aagaataaca agtacaactt tatcggttgg
     9661 attggcgcct ttgccctctt tatcctctta tctttttaca gtgttatcgg aggatggatt
     9721 ctagtctatc taggtattga gtttgggaaa ttgttccaac ttggtggaac gggtgattat
     9781 gctcagttat ttacttcaat catttcaaat ccagccattg ctctaggagc tcaagcgacc
     9841 tttatcctat tgaatatctt cattgtatca cgtggggttc aaaaagggat tgaaagagct
     9901 tcgaaagtca tgattcctct gctctttatc atctttgtcg tcatcatcga acgctctccc
     9961 agtttgccaa atgccatgga aggggttctt tacttcctca aaccagactt ttcaaaactg
    10021 actagcgctg gtcccctcta tgctctggga caatctttct ttgccctctc actaggggtt
    10081 actgtcatgt tgacctatgc ttcttacttg gacaagaaaa ccaatctagt ccagtcagga
    10141 atctccatcg tagccatgaa tatctcgata tccatcatgg caggtctagc cattttccaa
    10201 gctcggtccc ccttcaatat ccagtctgaa gggggaccga gcttgctctt tatcgtcttg
    10261 cctcaactct ttgacaagat gccttttgga accattttct acgtcctctt cctctttgcg
    10321 actgtcactt cttctgtcgt gatgctggag atcaatgtgg gcaatatcac caaccaggat
    10381 aacagcaaac gtgccaaatg gagtgttatt ttaggaattt tgacctttgt ctttggcatt
    10441 ccttcagccc tatcttacgg tgtcatggcg gatgttcaca tttttggtaa ggccttcttt
    10501 gacgctatgg acttcttggt ttccaatctc ctcatgccat ttggagctct ctacctttca
    10561 ctttttacag gctatatctt taaaaaggct cttgcaatag agaaactcca tctcgatgaa
    10621 agagcatgga aacaaggact gttccaagtc tcgctcttcc ttcttcgttt cgtcattcca
    10681 atcatcatca ttgtggtctt cattgcccaa tttatgtaat caaaaaggac ttgagtagtg
    10741 aactcaggcc ctttcttttt tatggatgac taacaattaa ttctaaatct tgcccttcta
    10801 aagtccaaga ttcaacatca cttagtacga taaagtggct ccctttttgg attggatagt
    10861 tttttccatc aacagtcagt tgaccttggc cagctaagat actaaacaaa ctgtaatcag
    10921 ctgtcttctc aaaatcaact tttccagtga tttcccactt gtaaactgcg aagaaatcat
    10981 tagaaacaag taaagtggaa cgcaaattat ctgctttaac agttacagga cggctatttg
    11041 ctggctcgcc aatgttcaaa acatcgatgg atttttcaag gtgaagttca cgcaagttgc
    11101 ccttatcgtc ctttcgatca aagtcataga cgcggtaagt tgtatcacta gactgttggg
    11161 tttcaagaat caagatgcca ggaccgatag catgcatggt gccacttggt acatagaaga
    11221 aatctccagc cttgacaggg actttggtaa gcaaggtatc ccagttcttg tcctcgattt
    11281 gctggcggag ttcttctttt gacttggcat tgtggccgta gataatctct gaaccttcat
    11341 ccgcagcgat gatgtaccag cattctgttt ttccaagttc gccttcatgc tctagtccat
    11401 aagcatcgtc tgggtgaact tgaacgctga gccagtcgtt agcatccaga atcttagtca
    11461 aaagcggaaa tacaggctca ggacgattgc caaacaattc gcggtgttcc gcatacaaag
    11521 tagcaagatc tgttccctcg taacgaccat tggcaacttt agaaacacca tttagatgag
    11581 ctgagatagc ccagtactct ccgacttttt cacttgggat gtcgtagcca aactcatcac
    11641 gtagcttggt accaccccag attttttctt gcataactga ttgtaaaaat aatggttctg
    11701 acatcttaat ctcctgtctg atttttctcc cctcattata gcaaaaaaag agttccattt
    11761 gaactctttt ttacatctta taaagcaggg agaagatttt ataaaaatag taaacaaatg
    11821 tgctctactc gatgcttaca ccattgctat caatgacatc cttgtaccaa tagaaggact
    11881 tcttcttgct ccgtttgaaa cttccatgac cagcattatc tcgatccaca tagataaagc
    11941 catagcgctt gttcatttcg cctgttccag ctgaaaccag atcgatacaa ccccaagtcg
    12001 tataaccaag caagtcaaac tccatcttgg taaatggcat ctcgcatggc cttgatgtgg
    12061 gcctctaagt aagtaatccg atagtcatct gctacataac cattctcatc cggtgtatcc
    12121 atagcaccga gtccattttc tacgataata ctaaactaaa atcaaaaagc attatataat
    12181 agtgatatga aatcaactaa agaagaaatc caaaccatca aaacactttt aaaagactct
    12241 cgtacagcta aatatcataa acgccttcaa atcgttctat agtaaaatga aacaagaaca
    12301 ggacaaatta atcaggacag tcaaattaat ttatagaaat attttagcag ccaaggtgta
    12361 ctgttataga ttcaatacac tatagactgt aatcaaacaa cgatttggcg aaatgtaaaa
    12421 aaatatgagg agttcggact cgactctctc cttcaagaaa cacgtggtgg tcgtaaccat
    12481 acatatatga cagttgagga agagaaagcc tttcttgctc gccatttgaa ggctgcagag
    12541 acaggagaat ttgttacaat tgatgcctta tttcaggctt ataaaaagga gttaggtcgt
    12601 tcctacacac gtgatgcctt ctatcaactg ttgaagcgcc atggttggca aaatattatg
    12661 ccacgtccag aacatcctaa gaaagcagac gctcaaacca ttgttgcgtc taaaaataaa
    12721 atctcaattc aagaaaacaa gaaagcgctt taaaaccagt agacgttttc gtaaggttcg
    12781 cttgatgtac caagatgaag ctggtttcgg tagaatcagt aaactgggat cttgttggtc
    12841 tccaatagga gtaggtccac atgtccatag tcactatata cgagaatttc gctattgtta
    12901 tggagctgtt gatgcccata caggcgaatc atttttctta atagctggta gatgtaatac
    12961 tgagtggatg aacgcctttt tagaagagct ttcacaagct tatcaagatg attatttttt
    13021 actcgttatg gacaatgcta tatggcataa atcaagtatc ttaaagattc cgactaatat
    13081 tggctttgca tttattcctc catacacacc agagatgaac tccattgaac aagtgtggaa
    13141 agagattcgt aaacgtggat ttaagaataa agcctttcaa actttggaag atgtcatgaa
    13201 tcaactccaa gatgtcatac aaggactgga gaaggaggtg ataaagtcca tcgttaatcg
    13261 gaaatggact agaatgcttt ttgaaagcag atgagtatta tatgcaattt ctttatataa
    13321 aaagatcgga ttgctccgat ctttcaatag ttcatattct caatttctat tttaaaaata
    13381 gctaaggtta acgtcaaatg actacgcgac ctatttcata cgataaaaat caagcactag
    13441 accagcaggt cctttaacta ataaggactc tgttccccaa tcggttacag ttggtccgtg
    13501 taaaaccttt ataccaagct cgttcaaccg tttgtagttc tggtctacat cctcaacctc
    13561 gatatgaata atgattcctg actgaaagtt ttccaaagga accaaatgat tttgtgacaa
    13621 cataagacag tgactgccaa tcgtaaactg agcaaaacca tcatcagcat aatctgcctt
    13681 tttatccaag atatgctcca agtcagcaca gacttgggga acatttgaaa cgataatatc
    13741 taattgattt aaattcattt actctcctcc ataaaaagac cgaattgctc cgatctttta
    13801 aagttccgct ctatgaaaat caaagaataa agtctacaag tttcatattt gattttcggc
    13861 gagaggaatt atttaattgc gcgtgattgc aatccttctt cttccaagaa gagacggaat
    13921 ggtacgagtt cttctgcttc gtatttttcc ttgaaggctt taatagcttc ttctgagtga
    13981 agttttggat ccaattcaag tacttctact ggaagtggac ggtgttgagt gatgcgagca
    14041 tcgatgacaa cagttttacc ttctttgttc aatttaacag cttctgcaac aactgcatcg
    14101 atgtcttcga tacggtcaac tgtgaatcca acagctcctt gagcttccgc aattttagcg
    14161 tagtcagcgt ttgtgaagtc tacaccaaac aagtgtttgt ttgtatcttc gtatttgttc
    14221 ttgatgaagc cgtactcagc atttgagaag acaaggttga taactggaag gtcgtattga
    14281 acgtttgtga taacgtctgg gtagcacatg ttgaatgctc cgtcacccat gatgttccat
    14341 acttggcgat ctggattgtc tttcttagca gcgataccac caggaagggc aatacccatt
    14401 gtcgcaaaga gtggagatgt acgccacatg ttcttaggtg tcatgtgaag gtgacgagta
    14461 gatgtttgag tagtgttacc tacgtcgatt gagtagatag cgtcttgatc agcatgtttg
    14521 ttgattgcat tgtaaacttg atacaattgc aattcaccct cagttttacc ttcgagtttg
    14581 ttcatgtaat cacgccagtt ttggttgttc ttaacgtttg cacgccacca tggagttgat
    14641 tcaactgggt ttactttgtc aaggatagct ttagctgctt gaccagcatc accaaggatt
    14701 gaagcgtcaa gggcatgacg tttaccaagt ttgtaagggt cgatatcgac ttggatgaat
    14761 ttttcagtgt tcttgaatgc ttcgtaaact tcagcaaatg ggaagtttga accaaggaaa
    14821 agaactgtgt ctgcttcaaa gaccacttcg ttggctggtt tccaaccaac acggtaagca
    14881 gaacctgtca aaccttcata gttccattcg aaagcttcaa agtttttacc agttgtgatg
    14941 attggtgctt tgattttacg tgacaattca gtaatcactt caccagcttt aacaccacca
    15001 aatccagcat agataactgg gcgttcagca ttgttcaaga tttcaacagc tttgtcgatt
    15061 tcaacttcgt tcaaagcagg agcgatgaat gagcgttcgt atgaacctga accgtagtat
    15121 gagttttcgt cgatttcttg gaaaccgaag tttactggaa tttcaacaac agctggacct
    15181 tttttagaaa ctgcagcacg gcaggcttcg tcaattactt ttggcaattg ctcagcgtaa
    15241 gctacacgtt tgttgtaaac agcgataccg ttgtacattg ggttttggtt aagctcttgg
    15301 aaagcatcca tgttcaattc gttaactgga cgtgatccaa ggatcgctag gaatggagtg
    15361 ttatccatag ctgcatcgta aacaccgtta atcaagtgag tcgcacctgg accacctgaa
    15421 ccaactgcaa ccccgattga gccgccgaat ttagcttgca taaccgctgc aagagcacct
    15481 gtctcttcgt ggcgaacttg taagaagcgg atatctttgt cttcagccaa agcgtccatc
    15541 aatgagctga gtgttcctga tgggataccg tagattgtat ctacgcccca tgttttcaat
    15601 acgttaagca ttgctgcaga tgcagtaatt ttcccttgag tcatagtgat aactctcctt
    15661 caattttttt agacttggag aatacgatta catagaattg gaaacgttct ccaaattttt
    15721 actattccac tgtatcatat ttattctgac ttttctaaaa atctgctcaa aactctctat
    15781 tctctattct aatacagttt tgaaagtgct gtcatttctg ttttacaaca aagaaatcta
    15841 gtcattactt ttagtctatt ttactaaagt ttaacagaag agaactggtc agaacagata
    15901 cagaactaaa ggccatggct agacctgcca attctggatt gagagccagt ccaacacctg
    15961 aaaagactcc tgctgctatc ggaattccga cgacgttgta gataaaggcc cagaaaagat
    16021 tgagcagaat acgatgaaag gttttcttac tcatatcaaa ggcacgcacc actcctagga
    16081 ggttattagt tgtcaacacc aaatctgctg actcgatggc aatatctgtt ccagccccca
    16141 tggcaattcc cacatctgct acactgaggg caggagcgtc attaatccca tccccaacaa
    16201 aggctacttt gccagccgct tgtagtttat ggatttcatg gactttttct tctggcaaga
    16261 cgcctgcaat gacctcttca attccgattt gatctgcaat agcacgcgcc acacctgcat
    16321 tgtctcctgt cagcatgact gttttaagac cacgtttttt caactgactg atggctagct
    16381 tggcattttc cttgggaata tcttgtagtg caagcaagcc tttgatttca ttgtccacag
    16441 ccaagaacac aactgtctta gcttcttttt ctaattgttc tagtttttct tgataaatgc
    16501 tagaaatatc catgccatcc agcattttag catttccaag caaaacttgt tttccattga
    16561 tttgccctga gacacctttt ccgtgcaagg cttggaaatt ttccacagtg tgaaactcaa
    16621 gtccagcttc actcgctcgt ttcacaatgg cttcagccaa tgggtgttgg gaagcttctt
    16681 ctagggaggt agccaatcca agcacttctg tctcgtcgcc aataatatct gtgaccacag
    16741 gtttcccttc cgtcaaagtc ccggtcttat caaagacaag agtttgaact ttctggattt
    16801 cctgtaagac agttccattt ttgaggagaa cccccatctt ggcactacgt cctgtcccca
    16861 ccataagggc tgtcggtgtt gcaagtccca aggcacaagg acaggcgata atcaaaaccg
    16921 ccactccgta gagaagagag gacacaaagc tagctccaag cacgaccaca ctatccctga
    16981 gcaagacgaa ccaaacccaa aaggtcatga ttcctaaaat gacaactact gggacaaaaa
    17041 tccctgaaat cttatccgtc aagtcctgaa tcggcgcacg acttgtctga gctttcttca
    17101 caaaatctac aatctgagcc aaaacagtct ctgagccaac tttttctgct ctaaagacaa
    17161 gcgttccact atgattgatg gttgagccaa tgacagtatc tccaactgtc ttgtccacag
    17221 gcagactctc acctgtcacc atggattcat caatactaga gacaccttct actacgacac
    17281 catcaacagc aatcttttca ccgggacgca ctcgaatcag gtcgcctacc ttgacttgtt
    17341 ccaaaggaac ttggacataa ctatcatcac tcaagacttc tgcggtttta gcttgcaagt
    17401 ccagtaattt ctccacagct tgggacgtat tttttctcat tttttcctca aaaactgctc
    17461 ccaaaagaac gaaaaagagg ataaatccag cactttcgaa gtaaacaggg agaccagcaa
    17521 agagagcaac taggctatag aaataagcca ctagagttcc cagcgcaacc aaggtatcca
    17581 tgttggcatt gtgcttttta aaactggccc aagcactctg gatatatggc ttacccgcaa
    17641 ctaacataat aggcgttgtt gctaaaaagg ttccccaatg catgacttga tgactaatgc
    17701 tacctgccaa catcccaatc atgagaatca caagaggcac agtaaagata ctagtaatcc
    17761 aaaaacgttg caggagagat agagattttc gagtcttctc aacgactata tagcttccct
    17821 tttgcatctt catgccacaa gaaaattcat gtctccctaa ttcttgaggt gtaaaacgaa
    17881 tgactttctc ctcatctacg ccgattgctt ccaagatacc ttcttcttca aacagaattt
    17941 ccttataaca gtttgaagga gtagcacgat gaaaggtaat ctcagctgga attccctttt
    18001 gaagctggat atgggctgga tgatagcctt tttcagctcg gatacggatt ttttgaatgc
    18061 cattttctaa gcttgctttc acaatttctg tcatagtctc cacctactct acaatcatct
    18121 tgccgtgcat catgttcata ccacaagcaa agccaaactc tccagcctgt tcaggcgtga
    18181 tttccactac atactcttcc cccattggca ggttcgcatg tacaccaaaa tctggaaaaa
    18241 caatttgatc cagacatggt gaaggatcct tgcggtcaaa gacaatgcgg gctggcactg
    18301 atttcttgag gacaatcaac tcaggagcat agccccccat gacttccact cgaatctctt
    18361 ggtatccgtt tttttgctgg gctttttgtc cagatttttc aggctttttg aaaaaccaaa
    18421 acaagataaa cgcgataagg gcaatacaaa taatggttac aatactattt aacatggcgt
    18481 ctcctttaca tacaattaca tcttacttct gttacagcac ttgatttctt ctctgaaatc
    18541 acagcttcca agtcttccaa gtcagtctga gtaaattcac attctacaat caagtcagcc
    18601 aacaaattcc taatcctacg ggaacaaacc ttgtctttga tatcttggac aagtaaatcc
    18661 cgactttggt ctagagttaa aagggctgaa taaacaaagg acttgccttc ttttttccga
    18721 gtcaaacact ctttctcaac tagacgagcc aaaagtgtct gaaccgtgga cttggaccag
    18781 tcaaaccgct ctgccaaaac cctaatcaaa tctgtactgg tctgctcccc ctgcatccaa
    18841 ataatcttca tgacctgcca ttctgcatct gaaatctgca ttaccatacc tccaaaatct
    18901 atatttgtca attacactca acagtatact ctcaaaatct acatttgtca attatagaaa
    18961 taatattttc ttcgaaaaat agaattttaa tcatttgaaa aacgatttgc agtcaaatat
    19021 tactatataa acaataaaaa tatgctatac taaagaaaaa agaaaacaac cactaggggt
    19081 gcgtaaagct gagattaacg actgttagat ccctctgact caatctaggt aatgctagct
    19141 gatggaagtg gaaatgataa tggggactag cagtcttcta ttgcctttct aaaacagact
    19201 agcttgttct taagaataca aacttcagtt ggttgggagg ttttagatga cttatttacc
    19261 cgttgctttg accattgcag ggactgaccc tagtggtggt gctggcatta tggcagattt
    19321 aaagtcattc caagcgagag atgtctatgg aatggctgtt gtaaccagtc ttgtcgctca
    19381 aaataccaga ggtgttcagc taatcgagca cgtttctcct caaatgttga aagcccaatt
    19441 ggagagtgtc ttttctgata ctccacctca ggctgtaaaa actggaatgt tggctactac
    19501 tgaaatcatg gaaatcatcc aaccctatct taaaaaactg gattgtccct atgtccttga
    19561 tcctgttatg gttgctacaa gtggagatgc cttgattgac tcaaatgcta gagactatct
    19621 caaaacaaac ttactacctc tagcaactat tattacgcca aatcttcctg aagcagaaga
    19681 gattgttggt ttttcaatcc atgaccccga agacatgcag cgtgctggtc gcctgatttt
    19741 aaaagaattt ggtcctcagt ctgtggttat caaaggcgga catctcaaag gcggtgctaa
    19801 agatttcctc tttaccaaga atgaacaatt tgtctgggaa agcccacgaa ttcaaacctg
    19861 tcacacccat ggtactggat gtacctttgc tgcagtgatt actgctgaac tagccaaggg
    19921 caagagtctt taccaggcag ttgataaggc caaggccttt atcacaaaag ctattcaaga
    19981 tgcccctcaa ctcggtcatg gttctggtcc agtcaaccat acaactttta aagattaaga
    20041 aaaaaactct ctagttccca ctttaaggga attagagagt ttttatactc ttcgaaaatc
    20101 tcttcaaact acgtcagctt ccatctgcaa cctcaaaaca ctgttttgag ctgacttcgt
    20161 cagtcttatc taaaacctca aggcagtact ttgagcaacc tgcgactagc tttctagttt
    20221 actctttgat tttcattgag tattaattag gaaagaatgt catgcaactt tgttaaaaag
    20281 gcttgcgttt ttgcctcaat atcttctgct tgcatcaaat cacgtacaac agctacacca
    20341 gctatgccag tgcccataag ctgatcaata ttctccgaag tcaagcctcc aatagcaact
    20401 actggaatgg caaccgtttg gcaaattgtt ttcaaggtcg atatcagagt aatgggcgca
    20461 ttttccttgg tggtggttgg gaaaatggct cctgtaccca agtaatctgc acctgatttc
    20521 tccgcttcca gagctctttt aaccgtttta gcggtgacac cgaggatttt ttcaggaccc
    20581 aagacttgtc gggcaaccga aactgggagt tcgtcatctc caatatgcag accagcagca
    20641 tcaaccgcaa gacaaacatc caaccgatca tcgattatca aggggacctg ataggcatct
    20701 gttatttcct tgacttgttt tgccagttga taatattgat tggttgtgag atttttttct
    20761 cgcaattgga ctatggtaac ccctgaacgg caggccgtct caacttttgc aagaaagctt
    20821 tccacggaat cttgatagcg attggttacc agatatagtc taagcgcttc tctattcata
    20881 aacctctcct ttgatggtat ctagccaatt ttcatctctt cttaggagcg aaagctgatt
    20941 gagtacttgg taacgaaatt cttccaatcc cattccttga acaactattt tctcagcagc
    21001 gatattgaga taagagactg ctaagcaaga agcttcaaaa ccagtctttc cttggctgag
    21061 aaaaacagct gttaaggctc caaccaagtc tcctgtccct gttatccagt ctaattcagt
    21121 acagccattc tcaagtacag caacttgatt ctccgaaaca ataaggtcct tgggacctgt
    21181 gactaagaat gacataccag gataggtctg acaccagtct ttcaagactt gaagcaaatc
    21241 ctccgtttct tgatctttag cactcgcatc gaccccaacg ccgtgatgct ttaatccaac
    21301 aagacttcga atttctgaca tgtttccttt aaggaccgta ggtctatagt ctaaaaggtc
    21361 tttaactaag ctcttacgaa tggatgaagt cgttacgcca accgcatcta ctaccatcgg
    21421 gagagaagat tggtttgcat acaaagctgc catgcggatt gctttttcct tctcagctga
    21481 caaatgcccc aaattgatga agagagcctg gctttgctta gtaaaatcaa gaacttcacg
    21541 gggatcatct gccatgacag gtttgcatcc cagagccaaa atcccatttg ccagcatctc
    21601 acaagaaatc tcattggtca tacagtgaat gagggaacta gagcctatag gaaaaggatt
    21661 tgtcaatgcc tgcatcagtc tatcctttca gcaaagaaat atccttgcac ttttttaaag
    21721 aattcctgct tgattaaaaa tcgaaatgca ataaaggaaa tcgctgtacc aatcaaggtt
    21781 gctccgaaaa atcgaggagt gtagataaac caactaagct tagcagccga tcctgtaaag
    21841 agcaccataa caggatagga aacaatagaa ccaataatac ctgttcccac aatttctccc
    21901 aaggcagaaa agtaaaattt tcgaccgtac ttataaaaga gacctgctag aagggctcca
    21961 aaagtcgctc ctgtgagagc taaaggcgga atcccttgag tcgtcatacg gataaaggct
    22021 gtcactgtag ccatagccaa ggcataaaca ggtcccatca tgattcccgc tagaatattg
    22081 actacactgg acatcggtgc cattccctca atccgaaaga taggtgtaag gactacatca
    22141 agggcaatca tcatagataa aatggtcaat ttgtgaactt gtagttggtg ctttctcatg
    22201 tttctattct tctccttttt ctaaagactg taaatcgctc ttccatgtct ggtgttggta
    22261 agccatctcc caaaacttgg cttccatatg aacactgatg tggaaggcat ctagcatttt
    22321 ttgcttatct gtctcatcac tttctcgata gagctgattg accaatgctc cctcctctct
    22381 gatctgttgc tctaactcat ccgtaatata agtttcaatc cattgttgat agagaggatt
    22441 tggtgatggt ttaagattaa gtgatttgcc tatatcatgg tataaccaag gacaaggaag
    22501 caagcttgca aaagctatgg ctaagttcgg ttctgcaaat tgcctataaa tatgagaaat
    22561 gtaatgataa caggttggag cgattggatg ttgctccatt tcctggtcgt tgatttccaa
    22621 ttccttgaaa aattgttggc gaataaataa ctcaccctcc actaaaccct gagcattttg
    22681 tttcaagagt cttttcatct cttggtttga agtcttatca gccaaaagat gatagatttc
    22741 tgagaaaacc ttcagatagt aggcatcctg aatcaggtaa tagcggaaaa tggcaggttc
    22801 taaattcccc tcttgtaatt gtaaaataaa gggatgatga aaggaagcct gccaagcttt
    22861 cttggataat tccatcgcaa tatctgtaaa ttccataata actcctttat aaaaatagac
    22921 tggtttgaag caataaaaag aaaagcaggt agattaattt tgttttttta ggaatataaa
    22981 aaatccgata gctattcttc aactgtgcat gttcgtcata tccgtgagca gatagagctc
    23041 tcaggtaaag atggcgccac ctaaagactg tcatcagaac cttactgtaa atcaagggcg
    23101 accaaaaatg tagttcttga ccacgtaata ggcaagcttc tttgagggac ttgatttctt
    23161 gctgaatgag aggaaaggaa ttgaatacca caatcaaggc ataggaccaa gagcgtgata
    23221 gccccttttg agccaagtac aagagaagct cttttagtga aatagaggaa acaaagacaa
    23281 ggccgataca aactgtcaca aaggccctcg ttccaagcat aactgcctgt gaagcatctc
    23341 cgtgtaactg aactgcccag tagttggcaa aagatggtaa aatggcaagt atgatcatcc
    23401 aagctaacat tttaaatcga cggtaataga gcataaagag aatacaaaat gcgactaccg
    23461 aaagattcag agcaatcgaa ggaatgaaag atgtttccaa ggataaaatc agcaagaaga
    23521 gactgataat cggtgtctgg gttgctactt tgaccatact atctcacctc cccttgggta
    23581 ttgctactct gagatgtaag tggtttggta atggtcactt ctttcacatg ccgaagaccc
    23641 tgactagtca tctcaatcca ataatcaacc acagaaatca aagggtctaa acgatgacta
    23701 atgagcagaa aacttcttcc ttgattcctc tcctccacaa tccacttgca aaaataatgg
    23761 caggctctat catccaaacc tgcaaaaggt tcatctagca agatcacgga agccttactg
    23821 gtcaagatgg tcaagagctg aagaattttt tgctgaccac cacttaattg atagggactc
    23881 ttatcgactg cctgctccaa atcaaaatat cgtaaagctt gaaaaatccg ctgatttctt
    23941 tcagaatcag gtccatctaa ttgaagctcc tctcgcagac tgactcggat aaactgcttc
    24001 tcagcttcct gaacaatact cgtcagttca cggtacaaac tctttttctt tttcaggact
    24061 gtccccttcc atgcaatgcg ccccttatac ttttgaaatt gaagaataga ccgaaagagg
    24121 gttgatttcc caacaccatt gtcacccagg atacaggaaa ttccttggta aaatgtaaaa
    24181 tcagcaatcg aaaagaggga gcgatttcca aactcacaag tcgttctatc catatggaat
    24241 agttccgggc tagaagcaac ttcctttgaa gcaacctgtg tcatctcata ggaagggatt
    24301 tgaaacactt cccttagttt tccgtctctt agttcaacca tatggtcgat ataggcttta
    24361 tagtcagata aatcatggtc gcacaaaata actgtcttcc catcaagagc caactctttt
    24421 agaatctcca atatctcgat tctgctcttg cggtcaatgg aagcgaaggg ctcatccaag
    24481 agatataccc taggattcat ggcaaagagg acagccatcg ctgctttttg cttttcccca
    24541 cctgataggt gatgaatggg acggtgtaag attgcctcgc aacgacattg ctggacaacc
    24601 tctgctattt tagaatcaat ttcctgaagg tgatagccga tattctccaa ggtgaacatc
    24661 agctcctcaa acaagttctc catggtaaat tgatgattgg gattttgaaa gagaatgcca
    24721 accttctgga cacgtgcgat gatagaaagc tgactgacct cgctcccatc tatcaggact
    24781 tgaccactat agggaagaga actgacttgg gcaatgactt gaaaaaggct ggattttcct
    24841 gaaccactgc tcccaactaa caaggtaaag gcttgcgcat gaaaagtaaa atcaaacggc
    24901 tcagagaaga ttggggactg aatcgctcgt agttccagac ccatctatgc ttttcctcca
    24961 gttgcaaact gatgatagag tttgacaatg gcacgaacca agatggtaca gaagaaataa
    25021 acagaaataa aacgtaccac aagtaaggaa aggacaaacg gaagggaaaa ggcgtagtaa
    25081 cctaacttaa tgtattcata gacaaagcta acaagcgtaa tcccaatact attagcagtt
    25141 agagagagcc aactttcata gcgattctta gttacgataa aaccaaattc acttcccaaa
    25201 ccttgaacca agccagacaa aagagctcct agaccaaatt ggctaccata aaggacttca
    25261 gcaagcgcag ctagcacttc tccaatcgtt gcacttccga ctctcggaac aaagatggca
    25321 gcaatgggcg cagccataca ccagagaccg aagaggattt cattggcaaa ggcctgcaaa
    25381 ccaagaggtg ttaagagtag actgaaaata ttatacacat atcctgaacc aacgaaaacc
    25441 ccaccaaaaa agatagacaa gaaagcaagc aagataacat cttttaactg ccattttttc
    25501 aacataaaaa actccttttt taaagaaaag tgggacactc aagaagaccg acctaaatac
    25561 tttgtatagc agactgaatt tagaacagta cacaagaatg ctaaaatatt tctagaaatt
    25621 aatttgaatt ttctaattga tttgttcgca tcttatttca atctactata tcatcttcat
    25681 ccagtttcgt aaaagaaaaa actctaatta cagatacgaa ttagagttca gcttacaaga
    25741 ttagacagtt cttttcgaca tacgaaaaaa acatttcaca tttcccttcg ccagtcttaa
    25801 ctgtatcagg ttcaatgggt atcatctcag cctaaagcac cccaaatgtc tttattattt
    25861 aattatgtga ttattataac acacatttta tactagttca agaaattgaa ctggaaatac
    25921 agccttgcac tcacaaagac agcagatctt tcttttgcaa aaaacaaatg acctgtttga
    25981 tgaattagcc attcaagctg aatctggaca tagcttttta aaaaaggaaa atcctactta
    26041 cttagaatcc aaggatagat atctattgtt cactcatttc ccgaacagtt ttttctatat
    26101 tttttgcata cgatattgcc gaaatgattg aaacgccatc catattggtc tttataatgt
    26161 ctttaatatg tttcgtctgt atcccaccaa ttgcaactaa aggcatttgt ggcaatagtt
    26221 ttctcatcaa ttcaagacct tcataaccta tagcaccacc agcatcatat tttgactggg
    26281 tatcaaatac aggcccaaca cctacataat ctacatattc aacttttgat tgttgaaatt
    26341 cttcttcgtt tcttatagaa agaccaatta ttttatctgg catcaatttt ctaatttcat
    26401 caacaccaat atcatcttga cctacatgta cgccatcggc gtcaatttcc attgctaaat
    26461 ctatatcgtc attaacgata aatggaacat tgtatttttt acaaagttct ttaatttgga
    26521 tagctagctc aagtttttct aagccttcta aagcaccctc acctttttct cgaaattgaa
    26581 ataaggttat accacctttt aaggcttcct caacgactgt atatagattt tttccttggc
    26641 aagtagtcgt tccacaaata aaatatagtt ttagtaattc tttatgaaac atcttacttc
    26701 actcttttga atttcttgac atcttcatct gtaatttcat ataaggcatt tataaattca
    26761 actttaaatg tcccaggaag atgtccattt ggacgttttt ctgccatttc tccagcgata
    26821 ttgtaaacta acattgctgt ttctaatgat tttaattctt gacctttttc cagtccgata
    26881 aaacttgcta ctacagctcc taataagcat cctgtcccaa tgactttcgg catcatagca
    26941 ctaccattat gaatcgttac cacttctcca ttaacagcaa tggcatccac ttcacctgtt
    27001 actactattg gaatattgaa cttctcattt gctgctagag caatttcgtc aatattatct
    27061 acgcccgcac tatctactcc tttagatgcc acatctattc ctactaaaga ggcaatctcg
    27121 ccagcatttc ctctaatcgc tgctagttta taattgttga ttagatcatc tgctactttt
    27181 tttctatatt ctcctgctcc acaggctaca ggatctaaaa ctgctgggac attatatttc
    27241 tccgcaattt tcagagcagc ttggtataat ttccaatttt catctgtcaa tgttcctatg
    27301 tttattaata aaccaccagc atactttaac aaatcctcta aatctgctgg aaactcactc
    27361 atggctggtg agacgctcag tgctactaat ccatttgctg tgaaattttt tactacatca
    27421 ttggttatac aaatgaccaa tggtgctttt tcttttaata attttaaact tgtcatattg
    27481 aaatccttcc ttttcacttt atacgatcta ctgatttcga tttatttcta tctttcgtta
    27541 agaatttttt tcatttacat tgaatgattt atactcaatg aaaatcaaag agcaaactag
    27601 gaggctaacc gcaggttgct caaaacactg ttttgaggtt gtggatagaa ctgacgtggt
    27661 ttgaagagat tttcgaagag tcttacctca tcaaatttgt aaatatcatg agctttctct
    27721 agacatcgta accaatatca aaaaaagcta attctaaagc gactgcttga ttccagcgtt
    27781 gctgaagttc tgtcaaatct tctcgatttt taccgacacg attgagttcg tcaaccagaa
    27841 attgaaccca ctctgcaaag aaaggacctc tgtggagatt gatccattcc gaatgaatat
    27901 agacttcagg tagagccaaa tctttagaac cccagtctaa atagagacct tctgcaatga
    27961 ccagcataac caaaagatgg gcatagtctg atgaagccac cgccgaatac attagatcct
    28021 gaaaggcttt tgttacaggg tgcaaagtca cttctaggta gtcattctct gctactttta
    28081 actctttaaa agccttttgg aaataaccat cttcatctgc ttcaagaaag cctagttgct
    28141 tggcaaaacg aagcttggat tcaagtttat ctgcgtgagc tacgcaggca cccagcatgg
    28201 ataagaaggc atcaaagaag tgataatctt gaatcagata gtcctttaag accttattct
    28261 caattgtccc cgcaaaaagt tccttaacaa aacgatgatt gattgcagcc tgccaatcct
    28321 tctgactgct ttttaataat tcttcaacag tcaaacctgg ctgaaatgca tagtcttgtg
    28381 tttccatatt tacttctcct ctctttactt gttagtaatt aataaaacac caagaaatat
    28441 caagcaaaat cgtaattcca cttgatcctt ttaaagcaca tcgagagcat ttgcagagag
    28501 ctaactaaac aagcctatcc agtttatata aacaaaaaac tccaattaca atcaagaatt
    28561 agagttgact tacaagatta gatcgttcat ttcgccatac gaaaaaacgt ttcacatttc
    28621 ccttcgccag tcttaactgt atcaggttca atgggtatca tctcagctta aagcacccca
    28681 aatgtctcta ttatttaatt actgaaccag tatagcaaaa aatgaaagcc ctagcaagat
    28741 atttgaccga aaaatatctt tatatataat atattgaaac tagaatagta cacctctact
    28801 tctaaaacat tgttagaaat cgatttaact gtcctgattg atttgtccta ttcttatttc
    28861 attttactat agttttcgat agcgatttat tcttccaata cacgaagaaa aacctccaca
    28921 ttcagtgaag gcaatctgtt ttatcaatac aattttaagt cacgagggtc aactgggaag
    28981 gttgggttgt atggattgtg acggagctta aagtgtttga catcttcaat ggtctgagct
    29041 ccagacaatt gcataactgt cttcaattcc gcattcaagt gttcaaagac ttgacgcaca
    29101 ccgacactac caccgagagc caagccataa ataacagggc gaccaatagc taccaagtct
    29161 gctcctgaag ccaaggcttt aaagacgtgt tgaccacgac gaacaccaga gtcaaagaca
    29221 atcggcacac gtctatcaac tgcttctgcc acttcttgaa gcgagtcaaa ggcagctggt
    29281 ccaccgtcga tttgacgacc accgtggttg gttacccaga taccagaagc tcctgcagca
    29341 agtgaacgtt caacgtcctc acggcattgt ggtcccttga catacacagg aagaccagag
    29401 tattcagcga taaattctac atcgcgtgga gacaagcgtt gtttagctga tttgtaaaca
    29461 aagtccattg atttaccagc accttctggc aggtattctt caacaatcgg catgccaact
    29521 gggaagacaa aaccattacg cttatccact tcacgattcc cccctacagt agcatctgcc
    29581 gtcaagacaa tcgctttata accttcagcc ttcacacggt ccatgatgtg gcggttgata
    29641 ccgtcatcct tactaaagta aaattggaac caatggggtg tcccttgaag ggcttcagaa
    29701 atctctggaa ggtcaacagt agagtaagag ctggttgtat aaagagaacc aaactcatgc
    29761 acaccacgcg cagtcgccac ttccccctgt tcatttgcca atttatgagc cgcaacaggc
    29821 gccataatga ttggtgaaga tagtttttca cctgcaaatt caatctctgt acttggattt
    29881 tcaacatcgc aaagtgtatg aggaacgatg agtttgtggt taaaggcgcg gatattctct
    29941 cttaaagtga aagtatcttc cgccccacta gcgatatagc caaatgctgc tttaggaata
    30001 acttgttgcg ccattggctc caaatcatag gtattgatga agtctacatg accttctgca
    30061 ttgcttgttt tgtatgacat aaaatgccct ccttgattaa gtaagcgttt gctttttact
    30121 acacaactat aataactctt ttttcaatca ttttcaagag ttttgcttaa aaaccatctt
    30181 attttttcat acaatatact agccctactt tccttaaact ctaaacttta gtctatatta
    30241 agtgaatcgt tgagattttt tgctgccagg catttgaact acttttttat ttgctgattc
    30301 tatctactaa tactataaaa aacaagtgaa taagacacca gaacatcctc taataggacc
    30361 tatggactta tatcagtccc atatatactg tttaagcaag atactatcct agttgacgct
    30421 aacttcctat cccacttatt aattttttat ttatagtgaa tctgaacaaa tcaattgggg
    30481 aatccaagtc aatttctagt actttttgaa cagtttcagc gtactatcgt aaaatgaaat
    30541 aaaacatgca caaattgctt agggaattta aaccaatttc taacaatgtc ttagaaatca
    30601 aagtgtacta tttcaacttc aatatactac acttcatttt ctccttaaat tcagtctctt
    30661 tttgaatcaa aaaatcctct ggtaagagcc agaggataag aatttatttc attgttggga
    30721 agagcaatac atcacggata gttgttgtat cagtgaggag catgcagaga cggtcgatac
    30781 cgattcccaa accacctgtt ggtggcatac cgtattcaag agcttcaatg tagtcatagt
    30841 cgattcctgt cgcttcatca tcaccaagtt ctttggcttt agcttgggct tcaaaacggc
    30901 taagttggtc gattgggtcg ttgagttcag taaaggcatt accgtactcc ttagtcatga
    30961 taaagagctc gaaacggtca gtaaagcgtt ggtcttcagg atttttctta gcgagtggag
    31021 atacagctac tggatgtcca tagacaaagg ttggttggat taaagtttct tcaacaaact
    31081 cttcaaagaa ggcattgatg atgtgaccaa cctcagtgta gtgtttctca actggaactt
    31141 tcttctcagc agcgatagct ttagcttctt ctaaagtcat gtcttgccag aaatcgacac
    31201 cagtaatttc tctgatagca tccaccatat gaacacgctt aaatggttcg ttaatcttga
    31261 tttcagtacc ttggtagttg actgggccat cgcccttaac tgatttagca gcgtgttgga
    31321 taatgccttc cgtcaagtcc atgatgtctt ggaagtctgc ataagcttgg taaacttcga
    31381 tagaagtaaa ctcagggtta tgagtagcgt ccattccttc gttacggaag atacggccaa
    31441 tttcatagac acgttccata ccacccacga taaggcgttt taagtgaagc tcagtcgcga
    31501 tacgaagcac catgtcaatg ttttgggcat tgtggtgggt gataaatgga cgggcagcag
    31561 caccaccggc ttcattatga agaacaggtg tttccacttc aaggaatcct ttttggtcaa
    31621 ggtaacgacg gatttcagag atgatttttg aacgagtgac aaagcgttca aagctttcac
    31681 ggttagaaat caagtcaagg taacgtttac ggtaaattgt ttcaacgtct gtcaaaccat
    31741 ggaatttctc aggaagagga cgaagagcct tagacaagtg tgtgatgtgg gttgccttga
    31801 tagagagttc tcccatatcc gtacgcatca cttcaccttc gacaccaagg aagtcaccaa
    31861 ggtctgcttt tttgaagatt tcgtagtttt cttcaccgac agcatcctta cgaacgtaga
    31921 tctgaatctg gccttcgcgg tcttgaaggt gggcaaaacc aacttttcct ttaccacgtt
    31981 tggttaccaa gcgtcctgcg atagtagctg tttcgttttt atcgtgtaat tgttctttat
    32041 cgaggttggc atatttatct tttaattctt gtgaatttgc agtacgttca aaacgttttc
    32101 cgaaaggatc gattccttgt tcgcggagcg cagccatttt ttcacggcga acgatctgct
    32161 ggtcatttag ttcttccata tgttctgtag acatgggatc ctcctagttt tactcaaaat
    32221 tgaatacgat gagtcatttt ttgcgatact cccattttat cataaataag caagaaattc
    32281 acggataatc tttcaaaact aaaaagaatt tgacgccaag atcactgagc caaatcactg
    32341 aaaagactgg gataagcaag aaattccaaa atctcagaaa aggaacgact gctgagactt
    32401 attttgaaaa gaatcatcca gaaattaaac tccaaaaata tgaccaatac agtgactctt
    32461 accaagctct tcttgacgga cgtggagatg ccttctctac tgacaatact gaagttctag
    32521 cttgggcgct tgaaaataaa ggatttgaag taggaattac ttccctcggt aatccagata
    32581 ccattgcggc agcagttcaa aaaggcaacc aagaattgct agacttcatc aataaagata
    32641 ttgaaaaatt aggtaaggaa aacttcttcc acaaggccta tgaaaaaaca ctccacccaa
    32701 cctacggtga cgctgctaag gcagatgacc tagttgttga aggcggaaaa gttgactagt
    32761 cattaactct taaaaggggc tggattttaa gctccaatcc ctttttaaga ttttacctat
    32821 aacatcctga gtctatctaa gatgttcaat ctgaacacag tgtacatact ttatcttcta
    32881 ttgcatatac tttatcacat aagatacgaa tatcctcttc actatgacta gcaatcaaaa
    32941 ttgttgtccc tttttcacta gagagctttc taaacaatgt tctcatattt tctacacttg
    33001 atttatccaa ggcattcata ggttcatcta gtaaaagaat agagggattc tccataattg
    33061 cttgagcaat ccctagcttt ttcctcatac ctagcgaata agttttaact ttctggtctt
    33121 tttgctcata tagaccaact attttcagtg tatcattgat ttcctgatta ccaactactc
    33181 ctcgtatgct tgccaaatat tgtaaattct taaagccact ataataattt ataaaaccag
    33241 gttcttcaat caaagctccc aaattagctg gaatttttct ctcaggaaca atattttccc
    33301 cattgattaa cacttctcca taagacggac tatataaacc agctattaat ttaaacaata
    33361 cacttttccc tgagccattc gcaccagtaa ttcctataat ttccccctgt ttacaactaa
    33421 agttaaggtt ttgaaaaaca catgtttttt ttaatttcaa ctcaatattt tttaatgtaa
    33481 ttatttcatt cattctataa acctcctctt ttgacgagtg aaatagaaaa tgcttttaaa
    33541 aagaaagact aaaaatagca actgaagaaa taaatctcgt cctatatctc cattccctcg
    33601 attcaaaata taaaatagat aattagttcg atttcctaca aatagaccac caaacacaat
    33661 catgagtaaa aagaaactaa cgcaagcaaa gttcatttgt acattcgctc ctagtgcgta
    33721 taacataaag caaagcaagg atagcacaca agcattcaaa gaatcaacta taaacaaaac
    33781 tcctatatcc cagtttggta actgtaacat aaattgaatc actagaactt ttaccatgat
    33841 taaaataagt ccataaagaa aacaggtcca aatctgatac ctaatccaga gcttaataga
    33901 agaaaatcga atcacttcca gaaagaaatc ggatgctctt ctacgatata caactactag
    33961 aaaaaatgta tgaataataa accaatgaag caaccatata gataagacta aaaaagagtt
    34021 ttgactcaga ttaggccctt ttaaaatttc tataacaagt ctatcatttc cttctaacca
    34081 ataccataat cctaaacaaa tcaatatcca aaaaagaaca taaccccaaa agtacttggc
    34141 atagattatc tgattcaacc tccacatgtg actacttaac tttcccattt ccaactttta
    34201 cactctcctc cagtttctat gaacagaaaa tacagtcaat ggaattatga tagatagtaa
    34261 tgtaagccaa taaatcaatg catacggatt ggaatttacc atatactgaa aaattggcaa
    34321 taatccaatt atcccattgt tcaactgata aatccagaat aaggattcta caaataaaaa
    34381 agtaaacaga aatactaagc tcatgtttga ttttttaaac caagaaaaac tgctaatagt
    34441 aagtaaggat aaaaagaaat agtatgctat ataagagaaa aaaaatccta taaagaaact
    34501 agcattgttt gcaatactta taccataaaa ttctcttaaa aaatcaacct cctttatctc
    34561 caaagagaag ctaaaaccat tactaaatgc aattagaaaa atcaataaaa ataaagtcgc
    34621 cgtccaaatc cccgtactaa gagctgctaa tttgaaacta aaactggtaa agtgcttaat
    34681 tgatttcaga cgaatgcgac actccaacct attaaaatag ttattcatca aatgaaaaaa
    34741 gaacaatata tatgtgaacg gaaagcaata tactccagtc gtcatatctt gaagtaaaac
    34801 taagatccat tctaatacat ttggatggat tgaatattgg cgacagcgca ataaatatac
    34861 tgtactagat aaaacacagg atagcagtaa tataaaataa accaatactg ctaagaaatc
    34921 ttttttataa aattgaacaa attgtttcat tatacatagt cctctgaatg tagaaaaaat
    34981 gtaccataaa caaccaaaca actaacaaat aaaataaaag caagatgccc actaactaag
    35041 gaaagactga tatctttctg atatcccaaa gctagcgttg tcacaggttc taagtaagat
    35101 atcccaaagc tagcgttgtc acaggttcta agtaagatag ccctaaaata gcccataaaa
    35161 taccaccaac catcatatag gcaactggga tgaaaatagc tcctaatttt ttcttcacta
    35221 gcaaagcact agctagtcca aaaatagaga acacagcgcc ccaaactcca taccagagag
    35281 tcgtcacaag actatagaga aactgattag aatcaaataa ttcttttaag gcaccactat
    35341 aatctccaat ataaatttcc tgataaggag tcactaaaag attaattcct aataataata
    35401 aataggggag aaaaaagact agaaaagaag aaataattgc agtactacct acaatagcta
    35461 gatacctctt tttagaaatt cggcacaatt gtgctgttag aaaataactc tcagcatcct
    35521 ctattatctg actagaatag ggcagtgtac agataagtgc agctactagg ctaatcggtg
    35581 aaaatcctcg aatagaagaa gcggcaaaaa aaatcgataa accttcaatt ttataaatac
    35641 cattgaaagc aaggaaattt cctaaactca tgcaaagaag ggtcaaaaat aaagacatat
    35701 aaaaccgagg tgattgaacg actcgtacaa gattacaaat gaaaaattcc atccttactc
    35761 ctccttataa taaaaatagg gtgtagcatt cttttttcat gctacaccca caatcaacca
    35821 tctttaaggc ttactctgac aagtaagtta ataagaatct ggactccaag aacctgaagt
    35881 atgaattctt acatgatttc caaattgtgg cgccatagct aatctagtac cagaaccaat
    35941 ataattgtca ccacctccat tatagtacat gacaatccta gagccagacc ccaatgaata
    36001 taccggggta atatctgacc cactataggc gctacgaata gaggtattta accttttacc
    36061 gccaccagtg ctgtcactat tattaattcc agcagaggcg ttttctttct caagctcact
    36121 agttgtatcc gaaccccaac gcggcaacgt taaatcataa tttccaatct gtctagctaa
    36181 aactgtaggg agaaacaaac tagatgcaat tgtaactacg caaaaaagga atatattttt
    36241 cttcttttca tgacatcgtc ctcctaagaa gtgataaaca agatagttga ttgatcaatt
    36301 tgatacatat tacattttca ttatatcaat aaaagaaagc gttgtcaatt atttcattta
    36361 aaatattgtc atattttaaa tgaaatggta aaagaggctc ggtagcctcg tctctcttta
    36421 tcttactgac ctaaccttct tgccaatttt cttggtcttc tttaaagcgt tttagaagat
    36481 caaggccctc tggcgtgatg taaccttctt cttgggctag atggataagc tcgctatagt
    36541 ttgaaagcgt cacaagttta acaccagcat ctgcaaagtt cttatctgct tttggcaatt
    36601 ggtagctgaa aatcgctaca actccaagca catctgctcc ttctcgcttg gctgctgcta
    36661 cagcttcaag aactgaacca cccgttgaaa taaggtcttc aaccactacc attttttgac
    36721 cttgagctac gcgaccttcg atttgattac cagctccgtg gtcttttggt ttgctacgga
    36781 tgtaggcaaa aggcaagtcc atcttatcag caataatggc tccgtgtgga atccctgctg
    36841 ttgcagttcc tgcaatcact tctacttcag gaaaggcttc tttgatagct tccacaaaac
    36901 cattttcaat tagggtacga gtttctggat aggctagtgt cacacgatta tcagtgtaaa
    36961 tcggtgactt gataccagat gcccaagtga agggttcctc tggtttgagg taaacggctt
    37021 ggattttcaa gaggtggcta gcgatatctt tagcaagtgt catggtattc tccttttatt
    37081 tttctaatct agttctttaa ttccagtcct gtgtccattc atccttgatg gcatgataag
    37141 ctgcaacagg atcctcagct tgggtaatgg gacgtcccac tacgatatag tcactgccga
    37201 tttgataggc atcagcaggt gtcatgactc gtttttgatc tccaactgca acaccagctg
    37261 gacgaatccc tggtgtcaga cagataaaat ctggattggt agcctgcttg atgacttgta
    37321 cttcctgagc cgagcaaaca acaccatcca agccagcttc agctgtcttc ttggcatagt
    37381 gaatcacaga ctcttgcaga ctggtttgga tattttgaaa ctcctgcatc tgagcttctg
    37441 acgttgatgt gagctgcgtt acagcgatca atttggcttg actcccaaga ccttcacgcg
    37501 ccgccttcat catctctaca ccaccagccg catggacatt agtcatatcg acaccaagct
    37561 gagacaagac cttcatggct gacttgactg tattaggaat gtcatgaagt ttgagatcca
    37621 aaaagacact atgacccaaa ccttttaagt aggacacaat ctcaggcccc gctgcgtaat
    37681 aaagctccat ccctaccttg agataaaggc tttcttctgc tgggaaaaga gctaaaaatt
    37741 ccttgaccgc ctcaaaacta ggaaaatcaa gagcaatgat tggacgatgt tctcgcatag
    37801 gtttctcctt ttgcctttac tagtgagaga gtctggccaa cagaagccac gaaaaaagga
    37861 acctgccaac agcaaggttc cacgaaaaat gggtagtctc caccctttca ccgtctaacc
    37921 ttagctgcct ctctggactg ctttaaaggt tttttactat tctattattt ctactagcac
    37981 ttgtcaagta aaaacagcta aatccatgtt gactgctatt gaacacctca caagactctt
    38041 tccaaaagaa tagttaaaga ctttcacttc ggacagagaa aaagagtttg cttgttaccc
    38101 tttaattgaa caaatgggaa ttctgtttta ttttgcggat gcctattcat cttggcaaag
    38161 gggaagtaat gagaatgcga atggacttct tcgtgagtat tttcttaaac cgatttggca
    38221 acaattaccg aaaaaatcct taatgatgct ttgctagctt attaatcacc gtccccaaaa
    38281 atacttggat tacaagacag gttttgaagc acttatagag gagatttaaa aatgttgcat
    38341 tttttattgc aatttatcag ttatcttatc acccaaaact tctgcaatta gtatgagcac
    38401 tattgttatt tttctttttt cgtacactca aatcaaaata tagcaataag actattctgt
    38461 agaattgctg tcaaaaagat cagttcattt tttccttccc acttgtgttt ataatcatta
    38521 aaataactca attaagaaat tttctttttc ctaatagtta tcgtaattaa agttaataga
    38581 agaacaatcc aaataagtag tgttagatta ggaattagag ttttattcca tgaaaattcc
    38641 tcccattttg tgaaaaactt agtaaatagt cccataaaac tataatctgt tatcttcgca
    38701 actgtcttat ccaaaccaga tagcatcggt aagaaagcaa ctaaaatcat agcaggaaga
    38761 ctgataacct gagctactac ttggctcttc gcggttaaac ctatcaataa atagaataaa
    38821 atgatggata aagaggttag aagaacgatt gtaatataat taaaagtatg tacaattgta
    38881 actcctaaaa taagaggagt agttcccata atcacaaaag ttagcaaaaa aggaagaaac
    38941 atagttgata aaatgtattc ggagccttta acaccactca acagaagagt ttgtaaattg
    39001 tacttttctt tctcttcaga caagataata gttataggac ttccaacagc caaagccaaa
    39061 gaaaaaggta aacacatcat caaaagaact aatgcctgtt gatcgttgac cttcccctgt
    39121 gtttccataa gatatttata aaaatatgtg aaagcaaaag gcactaaaac ttgcaataaa
    39181 atactcttat tggaaaggat gatttgacaa cgcaaccata ccaaagccag aaaccgttta
    39241 agcatttagc tttcctcctg ttaatgtgat aaaaatatct tctaaagtag gctcacatga
    39301 atgaattgaa aaaatatttt ccagatcagc ctgagatacc tgttctagtg atgtaaaatc
    39361 aaaagttatc tgattcccat tataatctgt aaccttaatc tttttatctt tattatatct
    39421 ttgaatgagt tcagaaggag ctccttgctc aactaatttc cctttattta ataaggcaac
    39481 ataatcacat aaaagacttg cttcattcat atcatgagtc gttagaaaaa tcgttgtccc
    39541 tgctgttttc aattctaaaa ttaactcatg aattgttcga gaagttgtgg gatctagacc
    39601 tgaggtcggt tcatccagaa agagtacagc gggtttgttg ataagagctc gtgctaaaag
    39661 cattcgttgc ctcattccag tggataattt tcctgctacc atcttgcgac tatcatataa
    39721 tcctactcgc tttaacaaat tatcaacacg tgatttacta atattataaa atttactata
    39781 aaaaagaaga ttgttataca gagacatttt ctcataaaat ccacttgtat cgctaaccaa
    39841 tccaattctc tttaattcac cgcttgttaa attttgagat ttttgtccca aaataataga
    39901 ttgtccttta tcggcaagga gctgcccagt cagaatatta atcgttgtgg tctttccaga
    39961 accagatggt cctaaaaatc caaaaatctg accttcttta acagtgaaac ttatatcatt
    40021 taaagctatt ttatcaccaa aactttttga taaatggcta acttcaatca tactcattgc
    40081 ccctccttta tattctacat ttttacttaa catctattta cttagcttta tcaaataaac
    40141 gtcttaaaaa aaacaataac attaagcata taaccgttag caagattgtt tcaatattat
    40201 tgataatatg atacattctc aagcagtata aaataattat atatatgcaa atgctcatta
    40261 tacctatttt tttaaacata ctaagcctcc ttgctaaata ataaagttat ataataacta
    40321 agacacacta tacctaacat aataaatatc cacagcatta aaaatattat catactaata
    40381 aaaatatcca ctggtaactg aataaatgtt ctaaaattaa caagcaaaaa taaaatctca
    40441 aacgatgaaa aaagccatac tatattttcc aatgatgttt gaatattttt attgtagtaa
    40501 gcataatata tagcaaaaat aatacccaag aacaatacta ttaattgtgt ttctataaca
    40561 gtgaactgcc caatagcaga taaaaaagct actcctcctg ataataagca aaaacaaact
    40621 gaacgaataa atgttttcgc tctaatattg ttatctttca ctttattatt ttttttacaa
    40681 attggacatt ctccgttttc cagaacatat ttttcttgac ttagagcatg atttctcata
    40741 ttataaacgt aagcgttatc tattaggatt tcattataac atcccagaaa tattttaatt
    40801 attaaattag tcattatccc tcccaaaata gcaggcatct ctggtgtagt cggccacttt
    40861 gtcttatcag ataaagtgta cttatttata tctttgttta tattccgaca agcaaagcaa
    40921 gaaccgatgg tagggatata tatattatca ataataagat agcatccatt aaaccctcct
    40981 gatatgtagg atatcttatg cgatacagca aattgattga caatttttat aatatcaatg
    41041 ggcgtatcaa ttgctttaac gataaaatct atactcccat attccgcaac aatgttttct
    41101 aattcttcta ctgaagaaac tttaatagaa ataggtacta cctgaacatc tgaattatac
    41161 ttgtgtattt tttgagaaag aacattaatc ttctccttac caacatccga ctctgtataa
    41221 agaatttgcc tatttaaatt tgatggttct attatatcgt aatcagcgac aataagtttc
    41281 ctcactccat acatacttag acttagagat atataacatc ctaaggctcc ggctcctaat
    41341 actaatactg ttttattctg tattttatta tactcttcat tataaaataa cgaatagtaa
    41401 cctttagttc tagaatatct actatcaata tctatctcat ccgaaattaa aatttgttca
    41461 tttaatagtt caaatgttag tttactacct aatacttctt ctatctctaa tagttcctta
    41521 caactattaa atagatcgtt gataaattct tgcgaaattt gaggttctat agctatttcc
    41581 cgcatactcc gaccacgcaa atacattata ccttcttttt tataagcaaa aacataacta
    41641 tttacgtaga acatatttcg tccttcctct catatataat atagaaagca gtatagaaac
    41701 aactacccct cctatactac gaacaataat attaggtgtc aaaaattgta atagttgact
    41761 caaagggaaa taaataataa caaatgctat taaaagttga actatatatt gaaaattcaa
    41821 gttattattg ttagaattca agtatcttaa aataatacca ctatcatact gaaaaaaagg
    41881 aattgaatta ataaaaatca tacctaagtt aatgataaaa aataagagtc caagcaattt
    41941 atacgatgtg aacaataaaa caagtaaacc tgtaagtgat aaaatcgaat ttgaagcaat
    42001 tcctgctaac ataattttca aaaattgttt tttatttttt aggaattgca ccccacttaa
    42061 atctacaaaa aaagccaaat taaacaaaag tagcattatt ccacaatttg ggatctcaat
    42121 ttgataatta ttagcaatta ttgcatgact aaattcatgt atcgttgcag atataataac
    42181 aacaagcaac caaaataaaa gaatgtttag cgttattgga aagttttgga aattagtcaa
    42241 aatatccgcc ctataaatat acataataaa acattgcaaa ataagagcca atgggaaaat
    42301 accaaatagg attttttcaa aattcttatt aaatctttta tagtttaatt tttcagataa
    42361 tgttatatta aagtcccaag atattttaaa aatatttatc ttttttcgtg atttcataga
    42421 atctataagt cccattttac taagaacaat ataaaatctt aaataatatt tcttccctac
    42481 taacactaat aagtccgata tggtaaattc ttgacctatt agttgctcta accatttttt
    42541 ttcctgtttc ccaactaata catgtttctt actggatggt atatatagat gatactgtcc
    42601 ctcataagga gtaggtaata tcttaatctt atcaacaatt ctcataacaa acctaacctt
    42661 taataaataa aagaggggct aagtaaaaca tactctagtc cctcagtccg caatcaataa
    42721 aataatgact aattctatta atctcttgct gcaagactaa tacggaaaat tcaaatgact
    42781 gtctaaaatg aaattgaaaa agcttgatat tagtaagtga acaaacttca acaaccagca
    42841 agagcaagga ttgctaaacc aaatccgata cctgttgcaa gtccagctga aaaatcacta
    42901 actggtactg aaatttcttc aatttcctca aataaaaagt tatcttgcat gattatcact
    42961 ccctatcttt ttaacaacag gctactccaa ttaagagaac taccccagtt ccaagtaaaa
    43021 ctccccccca aaattcacca tctgtagggg ctacgatttc ttcaatttct tcaaataaga
    43081 atacttcatc tgacatatgt gttaccttct tcataaaaaa tttttttgta atcgattaca
    43141 ttgcaaatat aacataaaga aaaacagatg tcaaatatta aacgtaaaaa catggtcact
    43201 aaataactat aagagaaaaa gtaaacctag cgacgcgatg agcgctgggt cgtttggttt
    43261 cgattgctct cttcctcttg ttttttctgt tcttcttctt gttttttctc agcttccttg
    43321 gcctcttgtt tggctttttc ctcagcctcc ataatcaatt tatccgccac agtgtaactg
    43381 taaattccag cttccatgtc gaccacactc ggttctgaca attgtggctt aatcttactg
    43441 taatatggca gtttcttact catttcagat agaggaacca agacttcgtc cgaatcattc
    43501 atggtcaatc gaattaaatc ggatgtcacc ttgcttgggg ctaattccac cttttggata
    43561 gccgccttga gttctgggct aatttgagca agttctgaga caaaaacctt gatttgttca
    43621 ctatcattaa agagaactga taaataagtt tctggtaaac tgttcagact cacagaacta
    43681 gtctcaagct gaccactgga aagaatagga taatgatttt caccagaaat atagtaggcc
    43741 acaatatcat attccttgac cttaatagtg aacttagttg gaaattgata gacaagttga
    43801 gctgattcaa cccaatagtt agacttaatc tgcttttcat attttgcctt gtctagcaga
    43861 aggttaatcg tataatccga atcctgaatg cctgaagcct gtcgaatatc atcagctgta
    43921 gtttgcaccg ttccctcaac acgaatatct ttcatggtcg cataaggact gagcaagtag
    43981 gcagagacaa tcaataaaag cagacttgga aataaaatcg tgaaggctcg caagatatgg
    44041 ataccaggaa tctttgcttt ggctggtttt tcctttgtag cctttttagc aagcttttta
    44101 tcctgttcct ccttctcttt agactctggt tcttctttct cttctttctc tttgtcagcc
    44161 tctgaggatg ctactttctc ttctttctct ttgtcagcct ctgaggatgc tactttttct
    44221 tcagactctt ccttagctga ttctgaatct tcctggtctg tttcactctc ctggtcctgt
    44281 ttatcctctg acttctcaga ttcttctccc attcgagctt gtctttcctt ttccttctcc
    44341 tcagctagag ccgcctcttc ttcagccttc ttttttagat attcttggtt tcgtttctgc
    44401 cattctgata actctttcaa ttcttcgagg gtttctttgt cctcattttt cttatctttt
    44461 gacatttact ttccttatga taaatctttt ttcaacaatt gataaaaatc tgctagagat
    44521 ttcaattcct tagaagcttt catcttagct tggtaatctt ccttgtgact tagtaagtga
    44581 gaaagcttct cttccaaact atccaaggtc aaatcgcttt cttgaaggtc ttctgcatag
    44641 ccttttttta caaagtaagc tgcattttca agctggtcac cacgactagc ttcacgacca
    44701 agcggcacaa tgacatgcaa ttttgctatc gccaagagct caaaaatcgt attggcacca
    44761 cctcgtgtca caacaatatc agccaattcc atcaagggtt gatagagatc ggtcacatag
    44821 tcaacacgaa aaagattttg gctcaactca ttcaggctag aatctccagt tagattgata
    44881 atattgtagc gctctgttag ttctttctta tggtctgtca ccaattggtt aaagacacga
    44941 gcacctgcag aaccgccaac aaacaataca gtcggcaatt tatgattaaa gtggctttga
    45001 atatccacca attcatctgg ttctggattt ttttgatctg aaaccttggt cactgctccc
    45061 acatgctcaa ccttagacaa actcgaagct tgctcaaagg ttgaatacat cttagtcgca
    45121 aatttatagg cgattttatt ggccaagccc atagacaggt cagattcgtg aataaagaca
    45181 ggcactcctg acacacgcgc agcgataaca ggcggtactg agacaaagcc tccctttgaa
    45241 aaaagggtct gtggacgaag tcgcaacatg ataaagagcg attggacgat tccccagcca
    45301 actttgaaga cgtccagcat attttgccaa gagaaatagc gacgcaattt cccagtcgca
    45361 atggagtgga aagtgacatc caaacctgac ttaaggattt cttggtgttc gataccacgc
    45421 ttgtccccga tatagtggac ttcccaacca tcttcgatga acttgggcat taacaaaaga
    45481 ttgagggtaa cgtgtccaac cgtcccccca cctgtaaaga caattttttt catattttat
    45541 tcttttaact ccgctactgt gtcgataaag aggtcgccac gtacttcaaa gttagcatac
    45601 atatcccagc tggcattggc aggactaaga agaaccacat ctccttgagt cgcaagttca
    45661 taggccttgc gggtcgcatc tgcaatatct gtcgcctcca cataagcgac accagccttg
    45721 tctgctgccc gtttgacacg ttctgcagat tgacccagga tgaccatctt cttgagtcca
    45781 gtaatgtctg gcaccaattc gtcaaactca ttgccacggt ccaaaccacc tgcaatcaag
    45841 acgaccttgc tgttgtcaaa tcctgataag gctttttgag tagccaagat attagttgat
    45901 ttactgtcgt tatagaattt aacacccttg atgtcatcca caaactggag acggtgtttg
    45961 acaccaccga aggctgaaag agtttccttg atggtttgat tgtccacacc acgaagcttg
    46021 gctacagcaa tagtcgcaag ggcattttcc acattgtggc tacctggaac accgatttca
    46081 ttcactgcca tgactacttc accacggaag tagagttgac catcttccag ataagctcca
    46141 tcaacctttt caagtgttga aaatggtaca acagtggctt ctgtcttgga agccaagtct
    46201 tttgccaagt cttgattaaa gttcaagaca aggaaatcag ctgctgtcat cttgttctgg
    46261 atattccact tggctgctac atattcctca aataatccat gataatcgat atgagttggc
    46321 atgaggttgg taataaccgc aatctctgga tggaattctt gaacacccat gagttggaaa
    46381 gaagaaagtt ccataacaag cgtgtcctta tctgatgcta tttgagcaac ctgactggca
    46441 ggatagccga tattccctga taaaagacca tgttgcccag cagcagtcaa aacttcccca
    46501 atcatagtcg ttgtggttgt cttaccgttc gatcctgtga taccaataat cggtgcttct
    46561 gaaatcaaat aagccaattc cacctcagtc aagactggaa ttcccttggc caaagccttt
    46621 tcaatcatgg gattgttgta ggggatacct ggatttttca ccataagggc aaactcttca
    46681 tccaagagtt ccaaaggatg gccacctgta atgaccttga tcccttcttc cagcaaactt
    46741 tgggcagctg gattgtcctc gaaaggtttc ccatcattta ctgtcacaat ggtacctagc
    46801 ttgtccaaca aacgagctgc agattcacca gacttggcca aacctaaaac aaggactttc
    46861 ttatttttaa attgatctat tactttcatg tctcgaactc catttctact cctactattt
    46921 taccattttt atggaaataa aaaagccaca aagtgtgttt gtgactcttt cttctaactg
    46981 aatcttacca tatcatctat gtgataaatc ggtaactcga atgacctgat ccacttgctc
    47041 ccaaatcaga ggattatggg tcgcaataat aatggtccga ttcggatttt ttaaagattc
    47101 taggatggaa agtaattcct cagagttttt ggggtctaag gaagcggttg gttcatctgc
    47161 aaggatcaaa ggtggatcct ttaaaattat cttcgctagt gcaacacgtt gtgcttctcc
    47221 tcctgataac tcaaatatag gttgcttcaa atccaaataa gagaggttta cacggtttag
    47281 agcttgtttc atcaaagaga ttttctcttt ttccttcaac tttttaccaa ctaaacccag
    47341 attgagattc tctttgacgg tttggctttc aattaagcca aaatcttgaa ataagtatcc
    47401 taagtaatct ctaaagaaaa cagaaggctt aatgtcctta agagaagtgc catcatatat
    47461 gatttgccct ttgtcatatg gctctaatcg tccaatcata ttcaagagtg ttgtcttacc
    47521 acagccactt gtaccgatta aggcataaat tttcccacct tcaaaatgaa gattcgtatc
    47581 tgaaaatagc tgacggcttc caaatttttt agatatattc tttagttcaa tcatcctatt
    47641 ttcctttcat aattgtcata gaaacacgag attctttctg cgcttgacgg taaagcgtca
    47701 aaactgcact agctagaaag accaataaag tgagcaagcc aatcaccaag tctcgactgc
    47761 ttaaaataaa gagactagca ccaaatacaa aactggcaaa ttggctaacc atatactgag
    47821 catgtgtttc aaaaaatcgt aaacctgaaa ttcgtttaat caagatatct cggcggaatt
    47881 gctcgaaata tagaagattg acagaataaa agagtaacaa ggaactggct attccaacaa
    47941 tagctcctaa gattaaagtt gctgtttcag tttgaacttc attataacga gttagataaa
    48001 cacttcttcc ttctttaaga taggatactt gctcataaat tccagctttc ttcaagagtt
    48061 ctagcccact ctcatatcct ttgataaaga gttgttttcc agcattgata gaccaactag
    48121 ataaggatat aaaactatca cctgtagaag tcggcgtgaa tactactaaa atcggatcag
    48181 tcaaatactg agtggatacg ggattctcac cgttattata aacaaaccgc ttttctccca
    48241 ttgaaagata actaacgtgc gctttcatct cataatccaa aggagcactt gcctcctcac
    48301 cagattttcc ataataactc aatctttctt caaaaacttt cttaagttct gcttctcgag
    48361 agcgcaaatg ttctgggagc aagaggataa actcaccttt ttggagatgg gctaacttct
    48421 gtttggtctc agcatctacc acgacctttt ccttgtccaa ataactggga ctaacataga
    48481 gcgtattagc atctggacta taggtatcca gtgtctctcc ctgttcattt tttccttgtg
    48541 gattggcaaa atggagcaga ttatccttta cataaagagc ttgttcttct tcgattgctt
    48601 ccttggcaaa ggcataccac ttgctctgat tttctgtatc ttttcctcta tcacctaagc
    48661 caaaagaaat ttgataatag tctgctctat cctgccatgc ttgttttgaa atttcaagtt
    48721 ctttcaatcg ttggtaagac gtcaaacctg tcttaacagc gtatcctact gtaaagacag
    48781 caaccaactg acacaatagg gttaaaatca tcaggcgttt aaggggtaat ctccccttaa
    48841 taacgggaac taatgctttg taactcaaac tcattaggta aaggagcatt agtaaaattg
    48901 aaatcgccaa taaaaacaac agatagaaac taatcccaaa accataggtg gctaacaaga
    48961 taggataaaa caaaccttga ctaaaaagaa cgactccccc acctaggaag gaaaggaggg
    49021 ctgatagaag gagccatttg atatcagtag ataaagaatg ccccatgatg gataagagag
    49081 tctgaccaga aaagagtttt atacctgctg ctctcatttc cttaatccga gtaataatca
    49141 ccagagcaaa gaaagataag ccaaatattg ctaaactaat taaaataagg ggatttagta
    49201 atattcgaaa agcaagaaaa tagggcggta tctttcggtc agcacttgct ttataaccca
    49261 aatctcctaa tttatcggca agcttttctt tcgtcaagga gcctgacaaa aggagataac
    49321 tatttagcgg atcactacgt tcacgacttt cttggctagc ttcttggaat tcttttggta
    49381 aagttcccta accataagtt gcataagtaa agtgagtcgt cccatcctta ctcggctcta
    49441 caattcttct agctattaaa ctctgttctg agtttgcaaa attctccaat tcctgttcaa
    49501 atacctcacg cgtcggttcc tgagtatctt ttttgacacg aagtaaagaa acggaatcat
    49561 agcttgcata taaatattgt ggcgcacgta agacaataat ccaagcaagg aagaagctga
    49621 gaaaaaaagt tgataataat atgaatagtt tcttcatagt agactccttg gtagactcct
    49681 tgtaaacaaa attccccctg taatttctta caaggggaac gatttaaatc aatgaacgat
    49741 tagtcataat cacagtaaaa tgctacttgt tctccccatt tagtccaaat ccatgcatag
    49801 gaggtttttc cagcaggagc ttctccttta tcagaatgac catcccatct gctcacgatg
    49861 gatgaataat gatatttttt accatgatag taatttgaaa aagcccaacc acctcctgaa
    49921 ccttctccat atgtccatac tcctccatct ggatattgta cagcagttga tgcagctccc
    49981 aataatgtaa aacttgaaat aagaactaga gcaagtaatc tatgtttttt cgttttcatt
    50041 ttattttttc tttcaaaaaa agcacacctt gagcaacaat gcaacaaaat aaaccctcct
    50101 ctctcttttg ttgaaaccgc tttcttatgt gataagaata acatttttat tatttgttgt
    50161 caaggaaaaa atcgaatttt tagatatttt actatattac ctctatgaat aatattatat
    50221 agtagtttta tttcaaaata atatgcaacc agtactaagc aaatataaaa tagatgccat
    50281 taacgaattt tattcaagtt tttcccattc atactataca agtaaaagag atggtgttaa
    50341 ctaaaaagca attcaaacta ttgtaaaatt cctagcaaaa agagagccga aactctcttt
    50401 tttatcttct tttacttttt ttgactggca tgagtgtgat gtctctaaca ctaaagtaag
    50461 ctaggatcaa catggctatt gctaggaata tttctgttgg taattgaaaa attttcagaa
    50521 aagatagaac caataaaatc aagagtgcca ctaaaataca taccatagcg acgatattga
    50581 cagtcccttt aatgctttct ggtgtcgcaa atacatagag taggagcagt aaaattccta
    50641 ggactaaata gaccatcttt ctctctttct agctcttatt cagctgattt tttcttcttg
    50701 ttagctttct cacgctctgc tttgttaagg atttgtttac gcaaacggat agactcaggc
    50761 gttacttcca tgtactcatc gtcgttcaag aactcaagag actcttcaag tgtcaagata
    50821 cgaggcgtct tgataacagc tgtttggtcc ttagtagctg aacgaacgtt ggtcatttgt
    50881 tttgccttcg tgatgttaac tgtcaagtca ttttcacgag agttttcacc gatgatcatt
    50941 ccttcataaa cctcagtacc tgggttgaca aagatcgtac cacgttcttc gatagacatg
    51001 attgagtaag ttgtagcctt accagcatcg atagaaacaa gggcaccacg gtgacgtcca
    51061 ccaatttccc ctggaatcaa tggcaagtat tggtcgaagg tatggttcat gataccgtaa
    51121 ccacgagtca ttgacaagaa ctcagttgag tatccaatca aaccacgcgc tggaacaagg
    51181 aagaccaaac gagtttgacc attaccagtt gaaatcatat ccaacatttc acctttacgt
    51241 tcagaaaggc tttggataac agacccttgg tattcttctg gagtgtcgat ttgtacacgt
    51301 tcaaatggtt cacatttaac accgtcgatt tcttttacga taacttctgg acgagatact
    51361 tgaagttcat agccctcacg acgcattgtt tcgataagga ttgacaagtg caattctcca
    51421 cgtcctgaaa cagtccattt atctggtgaa tcagttgggt caacacgaag ggaaacgtct
    51481 gtttgcaatt ctgcctgcaa gcgttcttcc accttacgag aagttaccca tttaccttct
    51541 ttaccagcaa atggtgagtt gttgaccaag aaagtcattt gaagagttgg ctcatcgatg
    51601 tgtaggattg gaagagcttc tactgcatct atcggagtga tggtttcacc gacaaagatg
    51661 tcttccatac ctgaaacggc aatcaagtca cccgctttgg cttcttggat ttcacgacgt
    51721 tccaaaccaa agaaaccgaa gagttttgta acacggaagt ttttagttgt accgtcaagt
    51781 ttagaaaggg taacttggtc cccaacctta actgtaccac ggaagacacg accgataccg
    51841 atacgtccaa cgaagtcatt gtagtccaaa agtgacactt ggaactgcaa aggctcatct
    51901 gagttatcta ctggagctgg gatatggtcg ataatcgtgt caaagattgg tgccatagtc
    51961 gcttcttggt cagctggatc atctgacaat gaagaagttc cgttgatcgc tgaagcataa
    52021 accactggga aatcaagctg gtcgtcatct gcaccaagct cgatgaaaag ttccaagact
    52081 tcatccacta cttctgctgg acgagctgat ggcttatcga ttttgttaac aaccacgatt
    52141 gggacaaggt cttgttccaa ggcttttttc aatacgaaac gagtttgtgg catggttcct
    52201 tcataggcat ctacgaccaa gacaacaccg tcaaccattt tcatgatacg ctcaacttct
    52261 ccaccgaagt ccgcgtgtcc tggtgtgtcc ataatgttga tacgagttcc gttgtaagca
    52321 acggcagtat ttttagcaag gatggtgatt ccacgctctt tttcgatatc gtttgagtcc
    52381 atagcacgct ctgccaattc agtacgtgca tcaagcgttt ctgattgttt caataattcg
    52441 tcaacgaggg ttgttttacc gtggtcaacg tgggcgataa tcgcaatgtt acggatatct
    52501 tctcttaatt ttgtcatgat ttcctctata atattcaaaa tttattttct aactgaacga
    52561 ttataccata atttcaaata aataacataa ctcaagcaag tgtaaatgtt ttcactccgc
    52621 ttttcttttc acgtcaagcc ttttcaaagc aagcgactta tgataagata ggcacagtat
    52681 gcgtttagat aatttattag ctcaagaaaa aatcagccga aaggccatga aacaagcctt
    52741 attcaaaggg gacattctcg tcgatagttg cccagcccgc tccctagccc aaaatatcga
    52801 tacaggacta caagaactcc tttttcagga tcgaatcatt caaggctatg aacacaccta
    52861 tcttatgctt cataaacctg ctggtgtcgt tacagccaac aaagacaagg aacttccgac
    52921 cgtcatggac ctgcttccat ctgacatcca gtctgacaag ctctatgccg tcggccgact
    52981 ggaccgagat acaacaggac tccttctctt gaccgataac ggtcccttgg gcttccaact
    53041 cctccatccc caatatcatg tcgataagac ttatcaagtt gaggttaatg gacttctaac
    53101 acctgaccat atccaagcct ttcaaaaggg aattgtcttt ttagatggta ctgtctgtaa
    53161 acccgcaaaa ctagagattc tatctgcaag tccctccatc agtcaagcct ctatcaccat
    53221 ttcagaagga aaatttcatc aaatcaagaa aatgttcctc tcggttggtg ttaaggtgac
    53281 tagcctcaag agaatccaat ttggggactt cacattgaac ccagatttag cagaaggtaa
    53341 ctaccgccct ttgaaccaaa aagagttaca aatcattaaa aactatttag agatgagtcg
    53401 ataaaacaaa aaaagcttta aaactaaagc ttttttcttt tatttatcga aaaattaagg
    53461 cgattgctac aatccagtta actacagaaa tcacaattcc taagatatta agaatctttt
    53521 ctattttata gtctaattgt gactcttttt ggtatgaaat agccaagacc aatcctatga
    53581 tacccaaaat caggcctaca attggaaata acaaaccaag aataatcgac aagataccca
    53641 caaaaagtgg atttttcttc ttttctttca tgttctaaga actctttaaa ttttataaaa
    53701 attaattata ctataaaaca atagcttcat cctatcattc gactaatttg gaaataaggt
    53761 tagctagtct tcactttccc tttccaagaa tccaagccat aagaaaggat ataaatctca
    53821 gaaaagcctt gttttttcaa gtaaagagct gcatttgtaa ctcgttgcgc acgttggttc
    53881 tcgtagagaa ggacaggttt atctttacga agggctgcaa gactagtttt caactgactt
    53941 gaaggaatat tgcgtgcacg aaggatatgt tttctgtgga attctgctgg gtcgcgcaaa
    54001 tcaatcaatt gacccgtacg aatcaaggct tcaaactcct cattgtccac aattttagcc
    54061 gcacggcgaa tacgaagata gttaaagccc atccacgcca acattgctag tataagtgcc
    54121 cacaaaatcc aagtaaccat tagttctttt ctccattttt ctcaatataa tccaattcta
    54181 ccttgtgctc tctgcgaaga actgcttctg cctctagata gtctaattta tccatcaacc
    54241 ctgcatcgta aatccgagat agttccaact tcatcagttc aatatcatat aagcgttttc
    54301 ccatgtaaac aataatacca aatcgtttga ggaattgttg cacatcatag aatgttttca
    54361 taagactcat tctagcaaaa ttttgtgttt ttttcaagaa gagactcaca caatgctcct
    54421 tattttccta tcttctttag cgattctaag gcaagtgtgg tacaataaaa acatgagaat
    54481 tcaacaatta cattatatta tcaaaatcgt cgaaactggc tccatgaatg aggcagccaa
    54541 gcaactcttt atcactcagc caagtctctc caatgcagtg cgagatttgg aaaatgaaat
    54601 gggcattgag atctttatcc gcaatcccaa gggaatcacc ttgacccgtg atgggatgga
    54661 gtttctctcc tatgcccgtc aggttgtcga gcagacccag cttctggagg aacgctataa
    54721 aaatcctgtc gcccaccgcg aactctttag cgtttcgtct caacactatg cctttgtggt
    54781 caatgccttt gtctctttgc tcaagaaaag cgatatggag aaatacgaac tcttccttcg
    54841 tgaaactcgg acttgggaga ttattgacga cgtcaagaat ttccgtagtg aggtcggtgt
    54901 cctatttttg aacagctaca accgtgatgt tttaaccaag atgctggatg acaatcacct
    54961 gctatcccac catctcttca cagcgcaacc gcatatcttt gtcagcaaga ccaaccctct
    55021 ggcaaagaaa gacaaggtga aactgtctga tttggagaat ttcccttacc tcagctatga
    55081 ccaagggacg cacaactcct tctacttttc agaagagatt ctttctcaag aacaccacaa
    55141 gaaatccatt gtggtcagtg accgtgccac cctctttaat ctcttgattg gtttggatgg
    55201 ttataccatt gcgacaggga ttttgaacag caacctaaac ggagacaata tcgtttctat
    55261 cccactggat attgatgacc cgattgagct ggtctatatc cagcatgaga aaaccagcct
    55321 atctaagatg ggcgaacgct ttatcgacta tctactagaa gaagttcagt ttgatagttg
    55381 agaaatgata agaaccaata tgtaggctag caacaacctg cacattggtt ctttttactt
    55441 ataattaaaa gtttcccctg ccaacttatc agctagcttg ggaaagagag tataaaactt
    55501 atgggctagg ttcaacaaaa tcgggagatt gagttctcgt ttatttttgc ctataatctt
    55561 gacaatcttt ttagccactg catctgcctc taagaggaag cggtcaaccg atttaagata
    55621 agttccatct gggtcagctt ggtcaaaaaa tcctgttcgg attggacctg gattgactgt
    55681 tgtcacatag actccatagg gcataagttc gagtcgcaga gcatttgaaa aaccaatagc
    55741 cgcaaacttg gtcgctgagt aaagactaga cttgccagta gctattagac ctgccatgct
    55801 gacgatgttg atgatatgcc ctttgctgct ttccttcata cgagccgcaa ggtgacgaga
    55861 cagattcatc agggcaaagg tattgacctc aaacatctgg tgaatatctt tatcagcaat
    55921 ctggtcaaat ccctcaaaaa tcccgtaacc agcgttgtta atcaagacat caatcttgcc
    55981 atagcggaga taaagatcag ttaccagagc ttctagggct gaatcgtcgg taatatcaat
    56041 ttcaatcaat tctgcatggg aataatttcc gtagagttgg gctaattttt ccttatttct
    56101 accaagcaag atgagttggt cattgggcag gagtttgacc atttcttgag ctagaccacc
    56161 gctagctccg gtaatgagaa tagtaggcat acttatcctt tctgtgactg ctagatttcc
    56221 acttcttcca agtctttgac cacatggaca ttttcaaaaa ttgtggcagc gtctttcttg
    56281 agtttgctaa tatcttttga gaggaaacgg gcactgatat ggttgagtag gaggcgtttg
    56341 gcacctgctt ctaccgctac ttgtgcagct tgcatattag ttgagtgacc atggttacga
    56401 gcaatttttt catcaccctt gccataagtg gactcatgaa ctaggacatc tgcattgaca
    56461 gccagacgca cactggcatc cgtttttcga gtatctccta aaatagtgat aatcttacct
    56521 ggacgtggcg ctgagatata gtctgctgcc ttgatttcag ttccgtcttc caaaacaaga
    56581 tcctggccgt ttttgatttt accaaaaagc gggccgaacg gaacaccagc agccttgagt
    56641 ttttcagcat ccagcgtccc ttctagatcc ttttgcatga cacgatagcc agcacagaaa
    56701 atagtgtggt ccagctcctc tgcatacaca gtgaatttat cggtttcaag aattttaccc
    56761 agagaatctt ggtcaaactc atggaaatga atgcggtagg gcagacgaga acctgacaca
    56821 cgaaggctgg ttaagacaaa tgacttgatt ccttgaggtc cgtagatttc caaatctgtc
    56881 tgctcttcat tggcctgaaa ggcacggcta gaaaggaaac ctggcaaacc aaaaatgtgg
    56941 tctccatgca gatgggtaat aaagattttg ctgaccttac gtggtcgaat tgtggtttcc
    57001 agaatgcgat tttgcgtacc ttctccacag tcaaagagcc aaacttcgtt aatctcgtcc
    57061 aaaagtttca gggcgagact tgaaacgttg cgggctttag agggctgacc agcccccgtt
    57121 cctaaaaatt gaatatccat tcgatacttt ctaattaatc aatatataac atggctgtgc
    57181 ggttttccga tcggaaatag cgtttgccag aaaaagcagc agcttcttgc aataaatcct
    57241 cttggctgta gcctttgaga cgttttcgac catcagccaa tctttccaaa tcagtcaaag
    57301 ctgtgagact ttctaggctg acaacttcct cgtcctcgac aggcttcatg taaatcttac
    57361 cagactcttc aaagactaat tgatggggga aaatttgcgc aatttcaaag agcaagtcat
    57421 ccgagatttt ctcctcattt tcagagaaaa tccgaccaaa gccgtcactc tcataacaaa
    57481 aaccaaagga tttaccagac agattaagcc gaataaaaga cttattttct agggtgaaac
    57541 ttggctcagt attgtaaaga ttcagttcct gactgagttc tgcaaaataa tccgtcgcag
    57601 cctgaggact ttttttctga tagagttctg caaagtaggc attaacaaca cttggcggag
    57661 gtgtaataag tgttaactgc tcctgctctg tcttaccagc tagaagctga tccagataga
    57721 ccttgtccag acttgtataa cctccatact ttagagccaa agttttaata tcagtcataa
    57781 aattcttcta acctccattt atttttctcg gaaatgtagc ctgtaatcac ttcgccgtct
    57841 tcctgataat cacgttcttc cagaattgca acactctcta aatcatgaat cttgtaggac
    57901 tttgaaaaag gcactcgcag ggtaaatgct tcaaaaattt ccttaatctt atctagcaat
    57961 aatgcttgca agttttcacg actgtcctca gacttggcag aaatgagggt atatggcgtt
    58021 tgggtaggcg tgaaatcctc caccaaatcc gctttattat aaagcgtcaa gtgaggaata
    58081 tcttccatgt ccaggtcttt catgatggag agaaccgttt tttcatgttc ctcgtggtaa
    58141 ggattgctag catcgataac atgaaccaga aggtccacat gcttgctttc ttccaaggtt
    58201 gacttgaaac tggacaccaa ctctgtcggc aaatcttgga taaagccaac ggtatctgtc
    58261 aaagttactt ggaggttgcc tcccagatga atactcttgg ttgtcgcatc cagagtcgca
    58321 aagagctcat ctgcttcata ctgggtctta ctggtcaaga tgttcatgat agttgatttc
    58381 ccagcattgg tataaccaat caaaccaatc ttaaaagtgc tagactccaa acgtttttct
    58441 ctgacagtcg cacgattttt ctcaaccacc ttgagctggc gctcgatatc cgtgatttga
    58501 ttgcgaacgc tacgacggtt cagctccagt tggctttcac caggaccacg ggaaccaatt
    58561 ccccctgcct gacggctgag cataatcccc tgaccaacca agcgaggcaa gaggtatttg
    58621 agttgggcta ggtggacttg gagcttccct tcatggcttc gagcccgcat ggcaaagata
    58681 tccaaaatca actgcatacg gtcaatgacc ttaacaccga gaacttcctc tagattgaca
    58741 ttctgccttg gggtcagacg gttgttgacg atgacagtag tgatttcttc tgcatccacc
    58801 ataagcgcaa tctcttccaa cttaccagag ccgacgaagg tcttggaatc atatttttca
    58861 cgtttttgtc tgtagctatc tacaacgact gcccctgccg ttttcgctaa actagccaat
    58921 tcttccatgg agaggtcaaa actgtccata ccctgcaatt ccacaccaat cagcaggact
    58981 cgctcctctt ttttctccgt ttcaatcatc taaaaactcc tctatctggc ttaaaatgcg
    59041 gtcttgtaca ccagattctc caatctgata aaaggtgacc tgcatgcgat tacggaacca
    59101 ggtcagctga cgcttggcaa aacgacgggt cgcctgtttg agactctcac tagcttcctc
    59161 caaggtctgc tctccacgga aataaggaaa gagttcctta tagccaattc ctttagcagc
    59221 ctgtacatta ggggaatggt caaacagcca cttggcttca tccaaaagcc cagcctcaaa
    59281 catcaaatcc actcggtggt tgatacgctc ataaagttga ctacgttcat catccaagca
    59341 gataatcagc ggttcataca aggtctcttg attttccaaa tcctgaccaa aatgggcaat
    59401 ttctaaggca cgcatagcac gacgacgatt aaactgggga atctcaaggc ctgcttgatc
    59461 caccaaatgg gctaattcct catctgaata tggctccaaa ctagctcgat aagctaaaat
    59521 ctcctcatga ggagtctctc cacctaggtg gtaaccttct agcaagctct ggatataaag
    59581 tccagtccca ccggcgataa tggctagctt gccacggttg tgaataccct caatagtcat
    59641 cttagtttct gaaacaaaat caaaagccga gtaagactcg gttatctctc taacatcgat
    59701 taaatgatga ggaacagctg cctgctcttc tggactagcc ttggccgtcc caatatcaag
    59761 tcctcgatag acttgctggc tatctccact aaccacttcg ccattaaaac gctttgcaac
    59821 ttcaatagct agagccgtct ttccaacagc agtcggtcca acaatcacaa ttatttttgt
    59881 tttcatcttt tttccttgaa aaattcccat tttttcgtta ctattattat aacacaaaaa
    59941 ggtcagtcag aaaaatgtga cctcttgagg aggctggctg attgagaata taaaggagga
    60001 agactcatgg ctaaaggatt cgctaaaggt cttgtaacag gtgtcgcagg aactgtcgct
    60061 gccgttgcag gtgcagtata cgcatttaaa aagaaagtaa tcgaaccaga agagcaaaaa
    60121 gcagctttca tcgaagaaaa ccgtaaaaaa gcagctcgtc gccgcgtatc acgttaagaa
    60181 acaaaagaag ttgggattat tctcaacttc ttttttctat tcttttaaat agctaggtca
    60241 aacttcaact gtggcttaac agggtcataa tccaccaact caaaatcttc tgctttgata
    60301 tcaaagaaat tagtcccatc aggaacattt aaaaccaagc gtggttggca gtttgacggc
    60361 tcccgacgga gcaattcctg agcttgttca aattgattat catagatatg gaggttgttg
    60421 atgaagtaga agaacttccc aaccttccag ccaaaatgtt tggcaatcat catctgcaaa
    60481 gccacatact gcatagcgtt gatgtggtgg gctactagca tgtcattgga gcgctggatc
    60541 aaggtcgcat ccagatagat ttccccatca acacgccgga catcaaacat ggtctgaaag
    60601 gcgcacggga gcagcccatc tgtttcttcg aaagcttggt aatcccagag cgaaataata
    60661 ttgcggcggt tccaaggatt ggtttccaac tgtttgagaa gcttattgat aatgtcgtgt
    60721 ttcttaacaa cggcaccata gcgctcacca atggttcccg tgtctccaac ttcccagtca
    60781 ttccagtagt gaacattgta cttgtcatta agcacttcta agctatttga ctggtcttgg
    60841 taaatccaga gaacttcttt gatggcggat ttgattgcaa tgggacgcaa ggttgtgata
    60901 ggaaattctc ctttagataa gtcgtactcg gaaaaggcac cagttacata cttggaatta
    60961 gcaacagtcc catccttgta cttaggacga gcctgctctg agaaaacacc ttcctttaga
    61021 atgcgttcaa tattctcttt aaaaatcgta tctgcttttg tcatttcgtt tcacctcatt
    61081 cattgtccta actagtatag cataaaaaat aaaagaggaa cattactaac tctaggttag
    61141 cattttcctc tctcattatc ttattgcaat acaagtgatg ctgctccgat aactccagcg
    61201 tcatttccta gagttgcaag agctaattta gtagatgtgc gtacttgtgg gaaactattt
    61261 tcatcgtaaa ctttttgaac accttgtaga aggaattctc ccgcagctga cacaccacca
    61321 ccgatgacga ttgttgatgg gtttaggatt gaaccaatgt tagcacaagc gattcccaag
    61381 taacgtgaga agttacggta aacaatcaaa gcaaggtcgt ctccttcttt tgcgagatca
    61441 aagacagtct tagcagttac ttcttctccg ttatcaatca agcgtttcaa ggctgcatcg
    61501 ccttcgtatt catcggcata gcgacgagtc aagttgacaa tccctgttgc tgaagcaact
    61561 gtctcaaggc agcctttctt accgcaagta catgcgattg gctggtcaaa gtcaacagtg
    61621 atgtgaccaa gctcacctgc tgcaccagca acaccgtgaa gcaatttgcc ttctgcgacg
    61681 ataccgccac caacaccagt accgagtgtc ataaagacaa cgtctggttg gttatctcca
    61741 gcacccatcc agcgctcacc aagagctgct acgttggcat cattatcgat gaaaaatgga
    61801 atgcccaaag ctttttcaat cttttgtttg attggttgaa gggttttcca gttcaagttg
    61861 taggcaccga taacagtccc tttttcacgg tcaaccacac ctggtgatcc cattccaatg
    61921 ccttggaagt ccgctgctgc caatccaagc aagtccaaac gatgttgaat agactcaatc
    61981 atatcatcaa cgatatgact tccctcatcc aaaatgtttg tcttgattga ccattttcct
    62041 tggatttctc ctgctgttgt taagattgca aatttgatag aagttccacc aaggtcaatc
    62101 ccaataatct tttgactcat catattctcc tttttcattg tgtagtaatt gaaaatgctt
    62161 acagtactag tatatcaaaa tccattcact tatgcaaagg tttgcgtaaa tgaattataa
    62221 ggaatttttt cgcctaccag tatctgttaa tcatctaaat gatcaatggc atattgagct
    62281 gcatcatttg aaaatttatc aaaatcagaa gttaattgtc tatacatacg tttttttgac
    62341 atgtggaata acgaattata actttttgcc tttcctaaag cagcagaata ttcactattg
    62401 ctatcattac tagaagaagc tgtacttgct tgaccttcct tccaaactcc gtcatcgcca
    62461 acataataac gtccaccatc aacccattca ttgacagcca ttttaccatc cgattttaga
    62521 tagtaatttc cttgccatgt actgtaagca taagaaccat ctgatgtcaa ataataccaa
    62581 gcttgataag aagagtcata aatccattca cctttagcca ttttaccatc tgatttcaaa
    62641 tagtaattgc cttgccatgt actataagca tacgatccat ctgatttcaa gtaataccaa
    62701 gcctgataag aagagtcata agcccattcg ctctgggcca ttttaccatc tgatttcaaa
    62761 tagtaattgc cttgccatgt actgtaagca tacgatccat ctgatttcaa gtaataccag
    62821 gcttgataag aagaatcata aacccattcg ctctgggcca tttttccgtc tgctttcagg
    62881 taatagcttc cctgccaagc atttttcact ggatttccat ttccatcaaa gtagtaccaa
    62941 gcgccgtcct gcttaaccca accacttgtt gttgctgaac ttgtgttgat ttgagtagcc
    63001 gttgactgtt ttgctttaaa agcaccctta ggagcatttt tcaattcgca agccacacca
    63061 tcatgatcac ggtctaactt ggcagaataa ccaggttctc cctcgtgaat atccgaatag
    63121 ccattccccc aagcttcctt acagctcgaa aaatggatgt tttcttccgc caaaactggt
    63181 tgtgaaaaca aggctaaaac tggtaatgta gccagactca tttttaaaaa tagacgtttg
    63241 ttcatttgtt tctcctataa cgataatatc gattttagta ttattttaca aaacttattt
    63301 cagcaattca aggaaacttc tgatcttttc tacaaactcc tttggttttg ccttattcaa
    63361 gacatgaggg ccatcaggaa tgatctgaaa ctgcgaatct gtcaacagtc tatggagagt
    63421 tttcatagaa ctaagattcg gtctatcttt gctgccacaa attagtaagg ttggataggg
    63481 gcaaatccct gctatatccg ttaaatcaag tgtcttcaat tcctcagaaa ctccgatcat
    63541 aagagtctta tctgctccct gtttttcaaa tacccttttg ggaagtagtt taaaaatcag
    63601 caactgaaga taaaatagaa tattccctgc taatttaagc gggcatcctg atagaaccaa
    63661 agctcgaaga tttggtaaat cgtaactgga aagttctagt gccagggcag cacctaagga
    63721 caatccaatc aaaacaaaag gttctgtctc ttgagctagg tgttgataaa ctcgctcctt
    63781 ggctttttga tagctgctaa ctccagaagg aaataactca atagcctcag aaggataatc
    63841 tgtcagtaga tttcgaactt ctttccaaga ctctgctgac tgccctaacc catgtaaaaa
    63901 tatcagtttc atctagttct cctgtaagat taactcatac aagcctctca ctgcattaca
    63961 gccgtaaata gcttctgctt gggctaaatc tgccaaggtc aagactttct cttctacctg
    64021 tcctctttcc agcaaatgct gacggtaaat tcctggcaag attccaagtt cgataggcgg
    64081 tgtgtagagt ctcccagaaa ttttcagaac caaatttccg attgaggttt ccaatagctc
    64141 tccagctgca ttatggtaaa taatttcctg cttccttagg cccaagtgag gtcggtggct
    64201 tgttttgaag taggtaaatg cttgttgcaa attggcttcc tgaagacaga gttgggcata
    64261 gcagaaggtt cgactgagag gtgttaatac ttgacgattg acttctatct ctccagactt
    64321 gctaaggcta attcgcaagc ggtaatcttg attaacatca caatcctgac actcttcctt
    64381 tatcttttgt ttcaagtctt ctgcatcaaa aggagaagca aaatagcgac tagcttttct
    64441 cagcctttcc agatgttgtg cttcaaacag caggttcttc tggctgattt tcccagtagt
    64501 aattagctga aaacgagctt gtttacgata gagaacagct gccttttgat gaacctcttg
    64561 gtattcagat tcccaagtgc tatcccatgt aatgcctccg ccaactccat agattgcttg
    64621 acctttgtga agttgaatgg tacgaatggc cacattaaaa atccgtcgtc catttggaag
    64681 caagagacca atcgttccac agtagactcc gcgtggttga ggctctaaat ttttgataat
    64741 ctccatagtc gcaattttcg gagctcctgt gatggatcca caaggaaaga gagagcgaaa
    64801 aatggtaatc aagtcaacat ctgctcgcaa ccgactcttg atggtcgagg tcatctgcca
    64861 aacagtagaa tactgctcta cctgacacag atgctccacg tgctcactgc ccacttcaga
    64921 aatacggttc atatcattgc gcaagagatc cacaatcatc atgttttcag agcgattttt
    64981 ggggtcctgt tctaaccaac tggcctgttc aagatcttct tggtcagtta ccccacgctg
    65041 ggtcgttccc ttcattggtc tcgtagccaa ttcacggcca ttttgctcaa aaaagagctc
    65101 tggactcatg gaaatcactg ccatctcgtc atgttccaca taggcattgt agcccgcctc
    65161 ctgctctatc accatacgat tgtagatggc aaaaggattg gcatttaact tttgcttaag
    65221 ttggacggtg tagttgacct gataggtatc tccctgccgt aaatgatgat gaatttgggc
    65281 aatcgccttc tcatagtctg ctgcagacgt cacttcctgc caatcagaag gcaaatcaac
    65341 ctcatcataa gtcagaggaa taggggatgt ttctacacta tcatgaactg taaaatatag
    65401 caggtactct cccagtagag gagccttatg aactgcaaac ttctcctcaa aagcaggagc
    65461 agcctcgtag ctgacatagc ccaccacata atagccttgc ttttggtagc tttccacttg
    65521 tgccagcaag tctgccactt ctgctacatt tctcgttttt atctctttga taggctgggt
    65581 aaaggtgtat ctctccccca aagccctaaa atcaatcact gtttttctat gcatacctta
    65641 agtatagcat aaaaaggcag atcaagaaaa acttaatcta cctttttatg attttatggc
    65701 tctataatat ttgtagtggg taacccccct atggatatta cggagcctat tttgtgtaga
    65761 aaaaaaatcc cataagatct ataatgaaaa gcgacaaaac aactcattag aaagaatcat
    65821 atggaacaat tacattttat cacaaaactc cttgacatta aagaccctaa tatccaattt
    65881 atggatatca tcaatatgga tacacacaag gaaatcatcg ctaaactgga ttatgatgcc
    65941 ccatcttgtc ctaattgcgg aagccaaatg aagaaatatg actttcaaaa accatctaaa
    66001 atcccttacc ttgaaacgac tgggatgcct actagaattc tccttagaaa acgccgattc
    66061 aagtgctatc agtgctcgaa aatgatggtg gctgagactt ctatcgtcaa gaagaatcac
    66121 caaatccctc gtatcatcaa ccaaaagatc gctcaaaagt tgattgaaaa ggcttctatg
    66181 accgatattg ctcatcagct gtctatttca acttcaactg ttattcgcaa gctcaatgac
    66241 ttccggttta agcatgattt ttcttacctc cctgagatta tgtcctggga cgagtactcc
    66301 tttaccaagg gaaagatgag ctttattgcg caagatttta aaaaactcaa catcatcgct
    66361 gttcttgagg gcagaacaca agccatcatt cgaaatcact ttctgcgcta cgatagagct
    66421 attcgttgtc aggtaaaaat cattactatg gatatgttta gcccttatta tgccttggct
    66481 aaacagattt ttccgtgtgc taaaatcgtt ctggatcgct ttcacattgt tcaacactta
    66541 agtcgtgcta tgagtcgtgt acgtgttcaa atcatgaagc agtttgagcg aaaatcccat
    66601 gaatacaagg ctatcaagcg ctactggaaa ctcattcaac aggatagccg taaactcagt
    66661 gataagcgat tttatcgccc tacttttcgt atgcacttaa ccaataaaga gattcttgat
    66721 aagcttttga cctattca
//
LOCUS       DAVDHZ010000007        57663 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000007 DAVDHZ010000000
VERSION     DAVDHZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.007"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(12..1301)
                     /locus_tag="VUR46_000581"
     CDS             complement(12..1301)
                     /locus_tag="VUR46_000581"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET5456059.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVT
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGEVANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1379..2047)
                     /locus_tag="VUR46_000582"
     CDS             complement(1379..2047)
                     /locus_tag="VUR46_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5456060.1"
                     /translation="MSLSMSSADGENLKNEKLSIKYQFLTIYRNLRLVFLKSGQKNFG
                     FMLFAVLLINALGGSLGGIYNIFFLSHSLLNFSYTEALFISQVGALVAVIISSLTGND
                     YFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFFTLYVSGKVQPKISAMLMKN
                     LAPEVLARTSNFLGLLFTLSIPVGTVCFSLVAVWNIQLTWMLFVGISLLAIFLTILNL
                     KNDI"
     gene            complement(2333..2626)
                     /locus_tag="VUR46_000583"
     CDS             complement(2333..2626)
                     /locus_tag="VUR46_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456061.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALSCSAS"
     gene            complement(2817..3668)
                     /gene="rgg"
                     /locus_tag="VUR46_000584"
     CDS             complement(2817..3668)
                     /gene="rgg"
                     /locus_tag="VUR46_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET5456062.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFLPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFINAYYFK
                     RVIEEHFYKENETYFRIVYLWAEDLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3792..4133
                     /locus_tag="VUR46_000585"
     CDS             3792..4133
                     /locus_tag="VUR46_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET5456063.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            complement(4385..6088)
                     /gene="ilvD"
                     /locus_tag="VUR46_000586"
     CDS             complement(4385..6088)
                     /gene="ilvD"
                     /locus_tag="VUR46_000586"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET5456064.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6321..7253)
                     /locus_tag="VUR46_000587"
     CDS             complement(6321..7253)
                     /locus_tag="VUR46_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET5456065.1"
                     /translation="MVRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPRSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQDGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7247..8107)
                     /locus_tag="VUR46_000588"
     CDS             complement(7247..8107)
                     /locus_tag="VUR46_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET5456066.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFVARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETEW"
     gene            complement(8111..9457)
                     /locus_tag="VUR46_000589"
     CDS             complement(8111..9457)
                     /locus_tag="VUR46_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5456067.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(9470..9754)
                     /locus_tag="VUR46_000590"
     CDS             complement(9470..9754)
                     /locus_tag="VUR46_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5456068.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKICEEKGLI"
     gene            complement(9758..11788)
                     /locus_tag="VUR46_000591"
     CDS             complement(9758..11788)
                     /locus_tag="VUR46_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET5456069.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTDDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTPKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            11980..12987
                     /locus_tag="VUR46_000592"
     CDS             11980..12987
                     /locus_tag="VUR46_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET5456070.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGVFIFIMGVGSQNIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKFPFLGAKSSNDNDVNLEISKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQSSAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            12990..13190
                     /locus_tag="VUR46_000593"
     CDS             12990..13190
                     /locus_tag="VUR46_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5456071.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYASETIDEPFEIDI"
     gene            13342..13524
                     /gene="rpmF"
                     /locus_tag="VUR46_000594"
     CDS             13342..13524
                     /gene="rpmF"
                     /locus_tag="VUR46_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET5456072.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            13540..13689
                     /gene="rpmG"
                     /locus_tag="VUR46_000595"
     CDS             13540..13689
                     /gene="rpmG"
                     /locus_tag="VUR46_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5456073.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(13819..14202)
                     /locus_tag="VUR46_000596"
     CDS             complement(13819..14202)
                     /locus_tag="VUR46_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456074.1"
                     /translation="MKTKNIEIRRITFSKFEFNTHNTGEVEEDGRASINLNFPDREEG
                     QENQLILIKMEISYPDSQYRVIADIDARYSVLASDLPEDISQDDEFQQALITPMIEKF
                     RLYVGMFSEGAYGAVLIPNLNFNQD"
     gene            complement(14204..14791)
                     /locus_tag="VUR46_000597"
     CDS             complement(14204..14791)
                     /locus_tag="VUR46_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system HicB family antitoxin"
                     /protein_id="HET5456075.1"
                     /translation="MMKDKEYYLGLNYPILIEKIYDEGELLFTASIKELPGLIVYGES
                     LGEVYDEIELAKADWIEANLEWGRKIKEPFENSLEEYSGKITLRLPKTLHRDVKERSE
                     IEGVSLNQTIVQLINDGLFKQTQNAVEQLTEQFKDMTKKLSQTIAEKVSAPEQHIHQT
                     IIIKNQSEKIQPYKEQNITNNRLQDNKVVSWSIGG"
     gene            complement(14778..15035)
                     /locus_tag="VUR46_000598"
     CDS             complement(14778..15035)
                     /locus_tag="VUR46_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicA family toxin-antitoxin system"
                     /protein_id="HET5456076.1"
                     /translation="MGKEKELQKIKNNPKSVTPERLESLCKKYGFMWKQGTNHSITSH
                     ALLEESYPIPRHKPIKPVYMKKVIKMIEKVIELEEGLNDER"
     gene            complement(15153..15473)
                     /locus_tag="VUR46_000599"
     CDS             complement(15153..15473)
                     /locus_tag="VUR46_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5456077.1"
                     /translation="MYHTEISMFLRGEASQLAKYNKKSGKPYKDIDDLVDFGRPIHIV
                     PHMFRHSFVSVMAEKNVSLNVIREFVGHSEDSREIEKIYLHVMQKGKDKIEQAMIDLA
                     EIIF"
     gene            15629..15835
                     /locus_tag="VUR46_000600"
                     /pseudo
     CDS             15629..15835
                     /locus_tag="VUR46_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15998..16267)
                     /locus_tag="VUR46_000601"
     CDS             complement(15998..16267)
                     /locus_tag="VUR46_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456078.1"
                     /translation="MPKTKTLAELADVILWSFDFAIDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREI"
     gene            complement(16654..18534)
                     /locus_tag="VUR46_000602"
     CDS             complement(16654..18534)
                     /locus_tag="VUR46_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET5456079.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVSVAQSDQASISIKGE
                     DGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSVEELQEIEAYAQQFDMTF
                     VPCIQTLPHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDSMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILDGVVNRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(18528..19397)
                     /locus_tag="VUR46_000603"
     CDS             complement(18528..19397)
                     /locus_tag="VUR46_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5456080.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWHEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMTINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGIKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(19481..22117)
                     /locus_tag="VUR46_000604"
     CDS             complement(19481..22117)
                     /locus_tag="VUR46_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET5456081.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVTAFGRGVKPIGFDNQV
                     LEDEQFTSQFSKMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNRWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHNSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVESLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGYEVLENTARYAKILLKHELTVPVSADEKLEEEQKGIIEFMKREAGRSE
                     ELTNIPLETEFTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPGASWENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASGELG
                     DWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGSVVA
                     TGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLERPY
                     PVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(22308..23575)
                     /locus_tag="VUR46_000605"
                     /pseudo
     CDS             complement(22308..23575)
                     /locus_tag="VUR46_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
     gene            23746..25840
                     /locus_tag="VUR46_000606"
                     /pseudo
     CDS             23746..25840
                     /locus_tag="VUR46_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
     gene            complement(26078..26452)
                     /locus_tag="VUR46_000607"
     CDS             complement(26078..26452)
                     /locus_tag="VUR46_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface anchored protein"
                     /protein_id="HET5456082.1"
                     /translation="MIIQESAKLDAETAKEATDLLADAKKVFADPKASQDEVDAMVKR
                     IEDFMAKVSPATDHTSPAKDQAAQTPAVAPATAQAANANQAAANARTVAKELPNTGTA
                     DSTVAMVVAAASALPWSCRPSS"
     gene            complement(26609..28297)
                     /locus_tag="VUR46_000608"
     CDS             complement(26609..28297)
                     /locus_tag="VUR46_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET5456083.1"
                     /translation="MVREIKPHSPLPSQVQLAYLEDELVAFIHFGPNTFYNQEWGTGQ
                     EDPERFNPTQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSIKVSPWRRG
                     KGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAY
                     GNGGKFAEVWMDGARGEGAQKVNYEFETWFETIRDLQGDCLIFSTEGTSIRWIGNERG
                     YAGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQYPKSL
                     EELVEIYFHSVGRGTPLLLNIPPNKDGLFDAKDVERLYEFAAYRNELYKKDLALGAEI
                     SGSALSVDFACYHLTDGLKTSSGASDVGLPIQLELDLGSPKTFDVIELREDLKLGQRI
                     ATFYVQVEVDDVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYK
                     TPGLSKKEVVQELAFAEKSLAVTKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAY
                     QDEIQVLQFQAGESKKDLSIPTLYFAADKILDFYLNLTVGGQLIDQAHILVETR"
     gene            complement(28299..32028)
                     /locus_tag="VUR46_000609"
                     /pseudo
     CDS             complement(28299..32028)
                     /locus_tag="VUR46_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001250572.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4982 domain-containing protein"
     gene            complement(32266..37095)
                     /locus_tag="VUR46_000610"
     CDS             complement(32266..37095)
                     /locus_tag="VUR46_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5456084.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMDAQPVQATE
                     TSSTLISSHYLDEQDLSEKLKSELQWFEENKIEVKEGKEYYFVYRKLATRLPETGLFS
                     NDGTFILGAGLLLLSFTLIKRKRGASYFLVTVFAVGGWGASISAFENLVELQPALVKR
                     VEGQFLPSPERVQGYEFTGYYLVRDSSNKELSVDKVESPALSKKEDGSEPQSKKIVPQ
                     TASHFSSTEDFVQSPQPSYAVEKIVEAPVSKQAPDEIVPIGTKEEIAGNPKVEQPKAE
                     NNSDYKPSPEEGVLNATVEKPELLVTTEEIAFQTIEQEDASLAKGQTKVVQEGVVGER
                     TIYTEVTIVNGEKSSKVIENIVTKEPENKVIAVGTKEEVAPKPTQPVTPEPEEVKPVQ
                     PEKIEKKPIVENETETKPAAGIGQPRPGAEETPGEKQTPDKPEAEPKQPELASPAVGS
                     GREEDQSPAEQKGEENQLENPVEGAKDAGESAPQEPQKQPEQTAPSPEVNPSQGNEPA
                     PAVQPEPSAPQEQSDSQVQPTVPSPVTKEKVLDYKTVYTASPALNYKEQQVEVAGENG
                     KEVTTTSYSFDESTGKIVENTSTKIEKHPVDRVVKVGNVEETTSTTKRGEQFVADESL
                     DKGVKEVRNQGQDEETTTIRVYKVNAQTGDLTEPEVSTKVAKEMQAKITAVGTKPTVQ
                     SQEIPFKTVYKASPDLSYNVQQEETPGEKGRTVSTTKYTVNQETGAISEETTIENIPA
                     KDKIVKVGNVEKIVSPIEITELRKDNPELPKGKEEVEDAGEQGETTVTKTYEVNPETG
                     ELTNPVEKTETTKAMRQKVILVGTKEDKPHLLPINSELENAVNVTEATAEMRNVDLLT
                     NEKLKAQLAPSDIEINRDLFLKRKELRKTNPAITDEEVKEILRKEYLEKLSIKETLDA
                     TKTDLEASLKKVAAHTLSILGDNQQNREKVKGDIEANKEKILLGLSYINRFYNIDFGD
                     TNIRDILAYNPSSFGKKDLTSLDWLTYLGSMSYDELRLTNSPKTFEKYFGKITDKPTL
                     LEFLDYNRTTFTNMDGDTWLKKATKAIVVEKPSKQKPDEKVELYTKLTTPPEKYGAEN
                     LQIESRRQQNVAILLGLVNIKEPSVYAITNIATVTYGNIGTYMDTSLEKTNPVKYKEE
                     LEKVKALIELTATRQAAYVDTLYRITKEENRSKLVTNRVIVDTMKKYTADTSAGIGTT
                     WSKESGPTADKGVKDFMTPLGLYSPSQNVGAEANGVGVRYFIDRVLDDRGSATYSHEM
                     THLLDRTVLFNNHGRRDGTAAEFYARGIFENSYTPEKDTYFNLNFVYDESKKNGFYNK
                     TPDRFKTDADLKSYMHGSFDVLYSLDYLEAEATKQLTAEDKTKYFKKITPIASKGPRA
                     TVTYTNSAVKATHKSEKISEITLAEAEKLTDINSLIDNNILVNRYIINGFYATGDVKA
                     NGYYLVDMFDTIYGVSQNDSGMSGDITFRKQAFELMAALGYYEGFVPYVSNQYKQVAE
                     SENKPLSDTYIFNKILNGKSYAEFKKAQFKERVDRLNQLKPLTIQYEGQQISLTSQKL
                     KELMQKAVLAELAQIKAGNTTAQKFEFIETPVQKLKKAIYKAYLKDSDDFRQSIYNS"
     gene            complement(37413..38297)
                     /locus_tag="VUR46_000611"
     CDS             complement(37413..38297)
                     /locus_tag="VUR46_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET5456085.1"
                     /translation="MIFLIVCVFLLLIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     MRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38554..39411
                     /locus_tag="VUR46_000612"
                     /pseudo
     CDS             38554..39411
                     /locus_tag="VUR46_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
     gene            complement(40386..41891)
                     /gene="adcA"
                     /locus_tag="VUR46_000613"
     CDS             complement(40386..41891)
                     /gene="adcA"
                     /locus_tag="VUR46_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET5456086.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLFQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYVGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKFTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(41901..42707)
                     /locus_tag="VUR46_000614"
     CDS             complement(41901..42707)
                     /locus_tag="VUR46_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET5456087.1"
                     /translation="MLSLLSYDFMQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFLLISLVRRFIK"
     gene            complement(42700..43404)
                     /locus_tag="VUR46_000615"
     CDS             complement(42700..43404)
                     /locus_tag="VUR46_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET5456088.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVTISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENDQEVGHA"
     gene            complement(43404..43844)
                     /gene="adcR"
                     /locus_tag="VUR46_000616"
     CDS             complement(43404..43844)
                     /gene="adcR"
                     /locus_tag="VUR46_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET5456089.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQQFLTALVGEIK"
     gene            complement(43999..45267)
                     /gene="dltD"
                     /locus_tag="VUR46_000617"
     CDS             complement(43999..45267)
                     /gene="dltD"
                     /locus_tag="VUR46_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET5456090.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMRHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYEPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIGDVVKADAEKNTSNNDLGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(45260..45499)
                     /gene="dltC"
                     /locus_tag="VUR46_000618"
     CDS             complement(45260..45499)
                     /gene="dltC"
                     /locus_tag="VUR46_000618"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET5456091.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(45513..46757)
                     /gene="dltB"
                     /locus_tag="VUR46_000619"
     CDS             complement(45513..46757)
                     /gene="dltB"
                     /locus_tag="VUR46_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET5456092.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAAILPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILILLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGMIIELRDGVIKDFTLWKFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(46754..48304)
                     /gene="dltA"
                     /locus_tag="VUR46_000620"
     CDS             complement(46754..48304)
                     /gene="dltA"
                     /locus_tag="VUR46_000620"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET5456093.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQRHTYGDLKADSDS
                     LAAVIDQIGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMNFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(48325..48456)
                     /locus_tag="VUR46_000621"
     CDS             complement(48325..48456)
                     /locus_tag="VUR46_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET5456094.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(48791..49495)
                     /locus_tag="VUR46_000622"
     CDS             complement(48791..49495)
                     /locus_tag="VUR46_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET5456095.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(49563..51389)
                     /gene="glpO"
                     /locus_tag="VUR46_000623"
     CDS             complement(49563..51389)
                     /gene="glpO"
                     /locus_tag="VUR46_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET5456096.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYEEDGATFSLFRLKVAMDLYDLLAGVNNTPAANKVLSKEEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQIRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRVDVEAALANNDLAELKN"
     gene            complement(51420..52928)
                     /gene="glpK"
                     /locus_tag="VUR46_000624"
     CDS             complement(51420..52928)
                     /gene="glpK"
                     /locus_tag="VUR46_000624"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET5456097.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAMLPEV
                     RSNSEIYGKTAPFHFYGGQVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWIRDGLRMVENSPESEKYA
                     RDSHNDDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDAQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(53087..54514)
                     /locus_tag="VUR46_000625"
     CDS             complement(53087..54514)
                     /locus_tag="VUR46_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5456098.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKVLDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLC
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWSHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKAPSFFAGQHLPLGTEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQKMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFRGMAEEIFHTLPTFQQGTDLDKKILWEWLQLIEYMAEND
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            54679..55551
                     /gene="hslO"
                     /locus_tag="VUR46_000626"
     CDS             54679..55551
                     /gene="hslO"
                     /locus_tag="VUR46_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET5456099.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGSIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPVVGNGQFLVITDYGIGNPYTSLTPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKEEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            55538..56518
                     /gene="dusB"
                     /locus_tag="VUR46_000627"
     CDS             55538..56518
                     /gene="dusB"
                     /locus_tag="VUR46_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET5456100.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWANPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEGLLQLDKT"
     gene            complement(56584..57249)
                     /locus_tag="VUR46_000628"
     CDS             complement(56584..57249)
                     /locus_tag="VUR46_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456101.1"
                     /translation="MKKKTYIKLMVAIVLVSTLLLGACGNKKEATETSQSSSSKVASS
                     SKENKIQKSSSSISSEKSKVSSDQSEMATNQSQATQTSSAPESRQGQEDSSQQTPSTQ
                     QHSQAQSNQSTYDPTTDRKLQDKQAEHNKRYKSVLTMVDGDFSATAGNWKGANGETVT
                     VSSDGQFTVETVDGKKENYSIKGYSYTLDDGKYNVKVGDGKVIQITTGADGAVSSVSL
                     IQQ"
     gene            complement(57466..>57663)
                     /locus_tag="VUR46_000629"
     CDS             complement(57466..>57663)
                     /locus_tag="VUR46_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5456102.1"
                     /translation="ALLSPQGRQIFAQRKIDVEPVFGQIKASLGYKRCHLRGKRQVRI
                     DMGLVLMANNLLKYNKRTTQN"
BASE COUNT        16751 a        12936 c        10710 g        17266 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataaaatccc agtttttcaa agatttctga gaagttttgg
       61 ctgattgtct caagtgacac ttgcacttct tctcgagttt gattgttctt gaccgtcact
      121 tgtccgcttt cgacttcact ctctcctagg gtgatgaggg tcttagccgc aaagacatcg
      181 gctgacttga attgagcttt gagtttacgg ttgaggtaat cacgctctgc tttgaaacct
      241 tgttggcgaa gggcttgtac caactccaaa gccttgacat ttgccacttc acccaagact
      301 gctatataga catctagggc gttttcgata gggagagcca caccttgctt ttcaagaatg
      361 agaagcaggc gctctacacc aagcccaaaa ccaaatccag cagtttcagg gcctccaaag
      421 taagcaacca aaccatcgta gcgaccaccc gcacagactg tcaagtcatt gccctcaatc
      481 tctgtgataa actcgaaaat ggtgtggttg tagtagtcca gaccacgcac catattggta
      541 tcgatgatgt aatctactcc aagattttcc aacatctgac gcacagcatc aaaatgagct
      601 tggctttctt catcaagaaa gtccaagata gacggcgcat tctctactgt caccttatct
      661 tctttttcct tagaatccaa gacacgaaga ggattttcct ccaagcgacg ttggctatcc
      721 ttagacaagg tctccttgag cggtgtcaaa tagtcaatca aggcttggcg gtaggctgca
      781 cggctctcag gatttccaag agtgttgagg tgcaatttga caccttggat gccgatttct
      841 ttcaagaaat gggctgccat agcgattgtt tccacatcgg tagctggatt gctagagcca
      901 aaacactcaa caccaatctg gtggaattgg cgcaagcgcc ctgcctgtgg acgctcataa
      961 cggaacatag gtcccatata gtagaacttg cttggctttt gcacttctgg ggcgaaaagt
     1021 ttattttcca cataggaacg gacaacgggt gcagttcctt ctggacggag ggtgatatgg
     1081 cggtcaccct tgtcatagaa atcgtacatt tccttggtta caatatctgt tgtatctccg
     1141 acagagcgac tgataacctc gtaatgctca aaaataggcg tgcgcacttc tgcgtagttg
     1201 tagcgtttga aaatttcacg ggcaaagcct tcaacgtact gccacttagc agactcagca
     1261 ggtaaaatat cctgcgttcc ttttggtttt tgtaatttca tagggaatcc tctttaaact
     1321 taatagtctt attttaccat aaataaaggg attaaaacag tgagaaaaaa attaggattt
     1381 agatatcatt tttgagatta agaattgtca aaaaaatagc tagcaaggaa ataccaacaa
     1441 atagcatcca agtcaactgt atattccata cggctactag tgaaaaacaa actgttccca
     1501 caggtatgga taaggtaaac aatagaccta aaaaattact ggtacgagct agaacctctg
     1561 gagctagatt tttcatgagc atggcactaa tctttggttg aactttacca gacacataca
     1621 gagtaaagaa gagaaatagc aaaccaagca cgacttgatt gaataaatta gccaaaccaa
     1681 ctagactaag tcctacggtc gcccacatca tcaatctagg caaggactgc ttcccaaaat
     1741 aatcattgcc cgtaaggcta ctgatgatga ctgctactaa agcaccgact tgactgataa
     1801 ataacgcctc tgtgtaagaa aaattcaaga gagaatggct caaaaagaag atattgtaga
     1861 tgcctcctaa ggaaccaccc aaggcattga taagcaagac agcaaagagc ataaaaccaa
     1921 agtttttctg tccactttta agaaaaacga gacgcaaatt tcgataaatc gttagaaatt
     1981 ggtatttgat agaaagcttc tcatttttta agttttcacc atcagcagat gacattgaca
     2041 ggctcaattt gctttttcct aaaaagagga tagtggctga tactaggaaa aagcaggcat
     2101 tgattcccgc aacgagagaa aaattgttga ccgatagagc taagagccag actccgaaag
     2161 cttgaccacc aatagctgaa atataggtga taaactgtga aaaagaataa gcctccatca
     2221 aatcatcttc agctactttt ccttaataag aggcatacgc aggccacctg caaaatcact
     2281 gatgatatca ctaaggacat tgatcaaaca caggctagaa aaggcaaaga gactagcttg
     2341 ctgaacaact aagggctgct agaaaaaata gaaccgcctg aaacaaaccg ctatagacca
     2401 tccatttgac cttgtccctc gtgtaatctg cccgaatccc tgcaaaaact gtaaagaggg
     2461 tcggaagaat catgacaata ttcgccatag caacagcaaa agatgcttgt gacaaggtcg
     2521 atgcatagac gataaagacc aggttgaaaa tcgaagcacc aaaagcattg aagaagcgtg
     2581 acaaagtcaa gaggcgataa gcttgatttc taaacaatag tttcatagat aatctccctt
     2641 cttgttcgaa gttctacatc aagaatagct ttagtatagc acttatgaat ttgcgaaacg
     2701 attcttttga atatatgcaa caaacaaaat gagcaaaaaa acgatagaac ttttgtaatg
     2761 acctgagaga gggcaacagt tctatcgctt caaatttttt cttggtttgc agatattcaa
     2821 cattcggtcg tatttctata gtattcggca gatttattac agccaagcat ctcaaaaata
     2881 cggacagcat cctccatctt tttctggcct tccttgactc taccttgctt gctatcaagg
     2941 agatcttctg cccacagata aacaattcgg aaataggtct cattttcctt gtagaaatgc
     3001 tcttcgataa cacgtttaaa ataataggca ttgataaatt cttcacactc aatactagct
     3061 aaaaagccat tcaatagtat agtatgaaaa aggtttcgat tgccagacat ttccattaga
     3121 aaatcagatt tacgtaccat ttctcgtaca tatctagtaa aaagagaaac agataaaaat
     3181 ggagaactga ctgaaaataa attgagttca tagattcccc agatctcggt agaaaacaaa
     3241 taatcatgaa ggacttttcc ttcctctgct gttaactcta ccctttcatc tatgctcttc
     3301 atataagact tgatcataat ggcatttaga atatgtttct gtttgttgtg agaatgggca
     3361 tgcttttgat actccctgcg atataagtcc tcaagaggtg ctatattctt tggttccaag
     3421 acatctgtaa tttcttttct caactcagaa tctgtatcat actggaaacc tctcgccaga
     3481 aagaggatct cctccacact ggcagatata ttttccagag caaatagaaa cttttccacc
     3541 gaaagctcac tctgacctgt ttcaaaacgg gacaacatag acggcaaaaa ttgtcctccg
     3601 gttgcttgtc tcagtgagat atttcttgac tctcgtaatt gtctaaagac ttttccaatc
     3661 tgctccatag acttcccctt gattccgtat tttcttcatt ttatcatatt tttcagaaaa
     3721 ttcatcaaaa acttgccaaa ttgtcagaat tatgagaaaa taggggatat ttatcacgtg
     3781 gagggactgc tatgagagac gatatcaaaa tcaatgaccg tgctttggcc ttgcaagacc
     3841 aaattatcga aaaactagag aaagtttttg atacagatgt ggaattggat gtttacaatc
     3901 taggtctgat ttatgaaatc aatctggatg aaacggggct ctgcaagatt gtcatgacct
     3961 tcaccgatac tgcctgtgat tgcgccgaaa gcctgcctat tgaaatcgtg gcaggtctga
     4021 aacaaatcga gggtatcgaa gatatcaagg ttgaagttac ctggtcgcct gcttggaaaa
     4081 tcacacgaat cagtcgctat ggccgtattg cccttggact accacctcgt taagcaggcc
     4141 aatcactttt aaagatgaaa aaagcaagcc gaaaatggct tgctttttga tactcaatga
     4201 aaatcaaagg gcaaactaga aaactagccg caggttgctc aaaacactgt tttgaagtta
     4261 tggatagaac tgacgaagtc agctcaaaac actgttttga ttgtggatag aactgacgaa
     4321 gtcagtaacc atacctacgg caaggcgacg ttgacgtgat ttgaagagat tttcgagtat
     4381 gagtttattt tttacctgac ttgtccatat tccagaagtc tgtcacggct ccgcgtgaag
     4441 cagatgatac gatgtgggca tatttaccga ggacaccacg gctgtaaagt ggtggcaagg
     4501 ttgtttctgc cttgcgtttt tcaagttctt cttcggatac ggccatggaa atttctttgg
     4561 tatcttggtc aaccgtaacg atatcgccgg tacggagata ggcaattggt ccaccatcct
     4621 gagcttcagg agcgatatgt ccaacaacca gaccataagt accaccagag aaacgtccgt
     4681 ccgtcaagag ggccacctta tctccctgac ctttaccaac aatcattgaa gaaagtgaca
     4741 gcatctcagg cataccagga ccacctttag gtccaacaaa acgaacaacg actacatcgc
     4801 catcaacgat ttcatctgtc aggacggcct gaatcgcatc ttcttctgag tcaaagacct
     4861 tagctggccc aacgtgacga cgcactttaa cacctgatac cttggcaact gcaccgtcag
     4921 gagcaaggtt cccgttcaag atgataagcg gaccatccgc acgttttgga ttttcaagtg
     4981 gcatgataac tttttggcct ggagtcaagt ctgcaaagtc agccaagttt tcagctacag
     5041 tcttaccagt acatgtgatg cgatctccgt gaaggaaacc atttgccaac aagtacttca
     5101 taaccgcagg gacaccaccg acttcgtaga ggtcttggaa gacatactga ccagatggtt
     5161 tcaagtcggc caagtgaggc acacgttctt gaatcgtatt gaagtcctca agtgacaagt
     5221 caacatttgc ggcatgggca atggcgagca agtgaagagt ggcgtttgta gaaccaccga
     5281 gagccatcgt tacagtgata gcatcttcaa aggcttcacg agtcaagata tctgatggtt
     5341 tgagaccaag ttccaacatc ttaacaacag cacgtcctgc tgcttcgata tcttctttct
     5401 tatcagctga ttcagctggg tgagaggatg accctggcaa actcatccct agaacttcga
     5461 tagcagttgc catggtatta gcagtataca taccaccaca accaccaggg ccagggcagg
     5521 cattacattc aagacgtttc acgtcctcag ctgtcatgtc accgtggttc cattttccga
     5581 taccttcaaa gacagaaacc aagtcgatat ctttaccatc aagatttccc ggtgcaatag
     5641 ttccaccata ggcgaaaatg gctgggatat ccatgttggc aatagcaatc atagatccag
     5701 gcatgttctt gtcacagcca ccgatagcga caaaggcatc gacattgtga ccactcatag
     5761 ccgcctcgat ggagtccgcg atgatgtcac gagatgttag agagaaacgc ataccaggcg
     5821 ttcccatagc gatcccgtct gctacggtaa tagttccaaa ctgtacaggc caagcgcctg
     5881 cagatttgac accttcttta gccagtttcc cgaaatcatg caagtgaatg ttacatggtg
     5941 tattttccgc ccaagtcgaa atcactccca caatcggtgt ttcaaagtcc ttatctgtca
     6001 taccagtcgc acgaagcata gcacggttag gtgatttaac catgctgtca tagatgctac
     6061 tgcggtgacg tttatctaat tcagtcatct tatccctccc atttcagttt ttactattat
     6121 agcacaattt tcgcatgaag aacagaatga aattcttgaa ttttcagaaa attctataca
     6181 catgtgaaat atttaaaatt aaaaacaaca aagcggatta gtgcactttc tgatgaccag
     6241 aatatgcttt ttaatccgct ttctttaaat aacgtactgt aatttttaca gaaattcttt
     6301 cagataagtg tatttaacat ctatcttgca ttataaattt ctagaacctt ctcttttata
     6361 ttcgattcac tcaaaccata ctcattaaga agataatcca ttttccctac ttgaccgaat
     6421 ctttcttgaa cacccatccg atgaattttt gttattccat catcagagaa taattcacat
     6481 aaagcactgc caattccacc tatctgattg tggttttcta cagtaaatat agtttttcca
     6541 cttaacattg tttttatctg ttctggtatc ggtttgattc taaataaatc tatcacacct
     6601 actgaataac ctaatttaga cagttcatct gcaactcgaa tacttggagc aaccattatg
     6661 ccagaagcaa cgattacaag atcttccccg tgtcttaact caatgtagcc tttagaaaaa
     6721 tcctctccat cttgatagac agcctctgga gcttttctaa ttgttcgaat atattttagt
     6781 ccttttaagt ctaatgtctg gttcaatatt tcacgaaatt ggatatcatc agtagcttca
     6841 aaaatgattg atctaggaat taaacgtaac aagccgattt cttcaaatgg catatgtgtt
     6901 ccaccattca tctctgcagt tactcctgca tctgatccaa tcacagtggc atccaattgt
     6961 gcgtatccaa gagaaataaa taattgatca aatactcttc gtgaagcaaa aggaccaaat
     7021 gtatgaagat aaggtctaaa cccctgaata gacaagcctg ctgcaaggcc gaccatttct
     7081 gcttccataa tcccaacatt cacataacgg tctccgaagt tcttttcaag attattagta
     7141 gccatcgaac ttgacaaatc ggcttctaag actactatat cagaataact ttgattagcc
     7201 tctaaaagga aatctctata tacatgccgt aattctttcg tacttctcac cattctgttt
     7261 cctccaattc ctgacttaat ctttctacaa ctgaagttaa catttgtttc tcctctacag
     7321 tagggcgaag atgatgattg gatttcattt cttccagctc ttgaacccct tgacctttaa
     7381 tagtatctaa tacaatgcac ttaggtgatg aattatttga ctgttttaat tggacaatcc
     7441 cttcataaat ttctctaata tctgaaccct tgaccctaat ggattcaaat ccaaatgctg
     7501 aaaatttttc tacgaaatca cctggattac aaatatcctt tgtaaaacca tctaattgtt
     7561 ttttgttatc atcaacaaat acaattaagt tggataactg ttgatgagaa gcaaactgta
     7621 tagcctccca acattgtccc tcatttaact caccatctcc aacaatagca taagtataaa
     7681 agggactctt tcttattctc tgaccatatg caagtccagt tgcaacacta attccttgtc
     7741 ctaaagagcc cgttgtcata tctatgcctg gcgttagatt tctatcagga tgagacggta
     7801 atttggttcc atttgtattt aaagaatata agaattcttt gtcaaagaaa ccattcaaat
     7861 agagtgtact gtatagagct ggtcctccat gaccttttga taatatgaaa taatctctat
     7921 ctcgtgctac aaatatttct ggagtcattg gcattatttc accataaagc actgctaaaa
     7981 cttctacaat agacagactt cctccgtaat gtccgaatcc aagatgattc aatgttctaa
     8041 gagtatttaa tcggatgtta gtcgcaaatt ttcttaaccc atcttctcta tttttactta
     8101 aaatcatccc ttattcctcc tttgcagatg gctttttaat aaaggatact ccaaacataa
     8161 ctgctaaaat aagaacaaga ccaatcacaa tgcctgcttg tgagccaaat tgatttaaca
     8221 ttcctaaaat aattcctgat agaccaaaat ctgcatctga gaaagttgag ccttggaaac
     8281 caagtcctcc caaaactggc attaaaaaga ctggaagaaa actgattaaa ataccttgta
     8341 aaaatgctcc aatagtggct ccacgaacac caccagatgc attcccaatg acacctgcag
     8401 tcgctccaca gaagaaatga ggtacaacgc ctggtaagat aacaaccgtt cctgaagcaa
     8461 tcataattgc catacttact aaaccaccaa caaaactaga gataaatcca attagaactg
     8521 cattaggtgc ataagtataa acaatcggac aatccaaagc aggtttggaa ttaggtacaa
     8581 gacgctctga aataccttta aaggctggaa caatttcacc caaaataagg cgaacacctg
     8641 ctaaaataac aaatacccct gctgcaaatt gacctgctaa ttgtaaagca taaactagac
     8701 cacttgtacc actactgatt tctttttcta tatattctga ccctgcaaag atagctacaa
     8761 taatgtaaat aactgccatg gataaagtaa tactaacagt actatcacgt aaaaaagcta
     8821 aactctttgg aaatttaatg tcctctgttg attttgattt gtcaccgata aggctaccag
     8881 taaaaccact caaccaatat cccaaagaac tgaaatgacc taaagccacc ttgtcatttc
     8941 cagttaattg aaccatatat ttttgcacaa atgctgggga aatactcata ataataccga
     9001 gtgctaatcc tcctagtaag atgagaggca agctagtaaa gccagcaact gataaaataa
     9061 ccgcaatcat acatgccata tatagagtgt ggtgccctgt taaaaagata tatttaaatc
     9121 gagtaaaacg agcgattaag atattgaaca ccatgcctgc aaacataatc attgcagtag
     9181 ctgagccata tgttgttaaa gctacagcta caattgcttc attattcgga acaactccag
     9241 ataaatgaaa agcatgttca aacatggtac caaatggatt caaagaattt tgtacaattc
     9301 ctgcaccacc agatacaact aagaaaccaa caaaggtctt aattccacct ttaataatat
     9361 caggtaattt cttcttctga agaactaatc ctaagatggc aattaaagct actaaaatag
     9421 ctggtgtact aacaatatcc aatatgaact tcatcatgac gctagcctcc tatataagtc
     9481 ctttttcttc acaaatttta gtaattaatt ctcgtagttc gtccatatca ataatactat
     9541 ttaagatacg aacatctcca agatgactag ctgaatcagc tagatcacga ccaacaatcc
     9601 aaatatcagc tgcatttgga tctgctccac ctaaatcata atgttcaact tctacatccg
     9661 aaacattcaa atcactcaat acagattcaa tattcatctg taccataaaa cttgaaccta
     9721 atcctgaacc acaagctgta ccaattttca acattatcta atcctcctgt ttaattatca
     9781 ttttaatgtc atcatagttt tttgatgata ttaaagtttg aacatgattt ttatctctta
     9841 aaattgttgt taaatgtgac aaagccttta aatgactctc attatcaatg gctgcaatac
     9901 aaatcaacaa tcttacctct tgttctggat tatccaataa ataaatcggt tcttccaaaa
     9961 ctaacattga cattcctatt tcattcacac cttcatctgg ccgagcgtga ggaattgcta
    10021 ctcccttccc taaattaata aaaggtccaa actcttctac tttttgaatc attgcctcag
    10081 ggtagttctc agttatctta tcttgatcca aaagcggttt agctgctaaa cgaatcgcct
    10141 ccttccatcc taatttttgc gaactaacct gataggtttc tttggtaata agttgttcta
    10201 gcactggtac aatttccttt ctatcatttt tttgataaag ataattcttt aacgccaatc
    10261 ttaattccaa ttcttgtgta ataattccat atcttttgac aatattcagg atttgttcaa
    10321 tctcaaaatc tccatactct aaattcggaa aatcttttaa cactagttct actagttgta
    10381 ttgcttgctc ttcagtcatc ataaccgaaa ctagataatt tggcttttct gtctccacct
    10441 ttatggtaga aaaaaccata tcatagtcac tactagcttt cacctgtaaa tcatcaatct
    10501 ttggggttcc tataaactca atttgaggaa ataatgctaa tagattctct tttaacatca
    10561 atgaagaact aacaccatta ggacaaatga ttgctgcttt ataccatttt tgaggcaaag
    10621 tatctgcttt ctttaaataa cctccgaaat ggataacaaa atatgctgtt tcactatcag
    10681 gtatgggatt gtcaatagcg tccatcaagg gcatcaaaga atctttgact aattcaaata
    10741 aatcaggata atgttcttta acatgcaata catattcatt tgaactaggt aggccgaact
    10801 ttaatctata gtaagccggt ataaggtggc ggcgaagatt ttctctcaat ccttcccttt
    10861 gtttaaaatg taacaaagaa atatcttcca ttctacttat aatagcctct gttaattgat
    10921 taaagtaaac cggagcaaca tctacttcac cttcaaagca acttgataat aaaactgtga
    10981 tatagcgata atcatcctca gaaaacaccg tatctataat tcccaaatca accactgtat
    11041 ccaataaaat agtggttata tcttgaataa caggagatac taatgtctct gaaagacata
    11101 ctctttcaac atccctttga tacctacaca gaatgaatac taaaccgaaa aggcaaactt
    11161 ttaattgatt aacaataggt actagctgta gcttctcata ataatcttta actacctgat
    11221 ttatcaaatc atcagttaat gaataccccc aactggataa aacataatcc aaaccccaaa
    11281 tccctatgga ggattccagc aactcactaa ccatttgaaa agctaaacgg tgcttattcc
    11341 actctgaacc gtgtaaagta taaccttttg ctctactgta ccctagctcc aaatcattat
    11401 ctaacataat ctttcttaat gattgaatat cagataaggt tgtattctta cttactttca
    11461 aaaagtcttg gtaatgatta ttcgatataa aatctaatcg gcaaaaagtg taaagataga
    11521 ttaaagctaa gcgagtcgac tttggtaaaa ccaattcatc cgacttaata atatctgtca
    11581 aagactgctt cgtacgattt gataaactat agcgaccttg ctttttatcc agcactatcc
    11641 ccttattagc tagataaggc actaaataat ctattccttc tttgacttcc tttataggta
    11701 agctcacctt aacagataat tcatataatg atagctcaca atgatccatc aaagtcatca
    11761 aaataactag tgctctataa tcaaacattt ctcttccttt ctaactacaa ttatagtgta
    11821 aaagttataa gaataaaaga gtatttgagc acaatataat ctcacctttt aaaagaaatt
    11881 attgggctga aactttttag tgattatttt tcaactttct attgacttta taaattaaag
    11941 tgatatcatt tagatatcaa ataatgggag gtcattctta tgactgaaaa actaatcaat
    12001 tcaaaaccaa atggtgtatt cgcattgatt ctcattgagt tgacgctcgt acttggtgtc
    12061 tttatattta taatgggggt tggttctcaa aatatttttg gtattattat cggaccttta
    12121 ctaatcgtaa ttgcaggtct agctcatgct ggtttaaaag ttgtcaaacc tcaggaagct
    12181 ctggttctga cactctttgg taattataca ggtaccatca aagaacctgg tttttacttt
    12241 gtcaatccct tcagcgtagc agtcaaccct gcaaaccaca ctcgacttgg acaaagtggt
    12301 gatgttagca caaaatttcc ttttttagga gctaaatcat caaatgacaa tgatgtaaat
    12361 cttgaaatta gcaaaaaaca catttccctc aaagtcatga ccttgagcaa ttctcgtcaa
    12421 aaaatcaatg attgcttagg aaaccctgta gaaatcggta tcgcggtaac ttggagagtt
    12481 gtcgataccg ctaaggcagt cttcaacgtt gataactaca aagaatatct ttcattgcaa
    12541 tgtgatagcg ccctccgtaa tattgtccgt atctaccctt acgatgtatc tcctaatgtg
    12601 gatactacgg gtgacgggca agcagatgaa ggtagtctcc gtggctctag cgaaattgtt
    12661 gctaaccgta ttcgtgagga aattcaaagt cgcgtagaag atgctggctt ggaaatcctt
    12721 gaagcacgta tcacttacct agcttatgct ccagaaattg ctgccgttat gcttcaacgc
    12781 caacaatcat ctgccattat tgatgcacgg aagatgattg tagatggtgc tgtaggaatg
    12841 gttgaaatgg cactagaacg gctcaatgaa ggggaattgg tagaacttga cgaagaacga
    12901 aaagctgcca tggtttcaaa tctccttgtc gttctttgtg gcaatcatga tgcacaacca
    12961 attgtcaaca caggaagtct ttactaaaga tggctgaagc taaaaaaaag cagatccccc
    13021 ttcgactctc aacaaagtta tacgctgcac tcgcatcatg ggcagaagac gactttcgtt
    13081 cagtcaatgg gcaaatcgaa tatctcctca cagagtgtgt caagcaacgg aagaaagacg
    13141 gaaaatacgc atcagaaacc attgacgaac catttgagat tgatatttaa catcttctcc
    13201 tgtctgacaa gtcggacagg agaatttttt catctttttt tgtcaagtaa ctttacttta
    13261 caaacaaaat gtgttatcct agtatggttg atgaaaatca gtagattgaa tcgaatataa
    13321 atacctaaag gagaaatcaa aatggcagta cctgcacgtc gcacttcaaa agcgaagaaa
    13381 aacaaacgtc gtacacacta caaagtaaca gctccatctg taaactttga cgaaactact
    13441 ggagattact cacgttctca ccgtgtatca cttaaaggat actacaaagg acgtaaaatc
    13501 gctaaagctg catcagctga ataatagaag ggagatacca tgcgcgtaaa tattacactt
    13561 gaacacaaag aatctggtga acgcttgtac cttacttcta aaaacaaacg taacactcca
    13621 gaccgccttc aattgaagaa atactcacca aaacttcgca aacacgttgt gtttacagaa
    13681 gttaaataat tgagtaaacc aaaagccctt gaaaccaaca tttcaaaggc ttttttcttt
    13741 ttgttttagg aaaataactg aattttaact gattaaatat tccgtaatga tatatgaata
    13801 ataaaaaacg gataacttct agtcttgatt aaagtttaaa tttggtatca gaacagctcc
    13861 gtatgcccct tcagaaaaca taccaacata taatctaaac ttctctatca ttggtgtaat
    13921 aagtgcttgt tgaaattcat catcctgcga aatatcttct ggtaaatctg aagctaagac
    13981 cgaatatctg gcatcaatgt cagcaataac tcgatactga ctatctgggt atgaaatttc
    14041 catctttatc agaataagtt gattctcttg tccttcctct ctgtcaggaa aatttaaatt
    14101 aatcgaagct cttccatctt cttcaacttc tccagtgtta tgagtattaa attcaaattt
    14161 actaaatgtt attcttctta tctcaatatt ttttgtcttc attttaacct ccaatagacc
    14221 atgaaactac tttattatct tggagtctat tattagtaat attctgctct ttataaggtt
    14281 gtattttttc agattgattt tttataatga ttgtttggtg aatatgttgc tctggtgcag
    14341 aaaccttttc agcaatggtt tgactaagtt ttttagtcat atctttaaat tgctctgtta
    14401 gctgttcaac agcattttga gtttgtttga ataacccgtc attaatcaat tgtactatag
    14461 tttgatttaa gctgactcct tcaatttcag agcgttcttt aacatctcta tgtaaggttt
    14521 taggtaatct tagcgttatt tttccactat actcttccag agagttctca aaaggttctt
    14581 taatttttct cccccactca aggttggcct caatccagtc tgctttagct aattcaatct
    14641 catcataaac ttctcctaaa gattcaccat aaacgattaa tcctggtaac tctttaatag
    14701 aggcagtaaa caataattca ccctcgtcat aaattttttc aattaaaatc ggatagttca
    14761 atccaagata atattcttta tctttcatca tttaaaccct cctccaattc tatcactttc
    14821 tcaatcattt ttataacttt cttcatataa actggcttta tcggcttatg tcgcggtatt
    14881 ggatagcttt cctccaataa agcatgagag gttattgaat gattggttcc ttgcttccac
    14941 ataaaaccat attttttaca cagagattct aagcgttcag gggtaacaga tttggggtta
    15001 ttttttattt tttgcaactc tttttccttg cccatgatgt acctcattta cagcgacact
    15061 atatatggtg tcacaataat tatatcccaa aaattcgcta atttcaagga tttcttttaa
    15121 ttttaataaa atatctgaat ttcataagat aattaaaaaa ttatttcagc caaatctatc
    15181 atagcttgtt caatcttatc ttttcccttt tgcataacat gaaggtagat tttttctatc
    15241 tctctactat cttctgaatg tcctacaaat tctcgaataa cgtttaggct tacattcttc
    15301 tctgccataa ctgaaacaaa gctatgtcga aacatgtgag gaactatatg aataggtcta
    15361 ccaaaatcta ctaagtcatc aatatcttta taaggttttc cgcttttctt attatacttt
    15421 gccaactggc tagcttcacc tcttaagaac attgaaattt ctgtatggta cattgggcta
    15481 ccttgttgat ttttgccttt aacgtagatt ctagtaaata tatagcccat atctttataa
    15541 gttggataaa taataccatt aaggaaagtg caagggcgca tttgattgaa agccagggag
    15601 tgaaggcagt aaagtcaatg ccttttgccg taaatccagc aaactcaagc cgctaccagc
    15661 tgaagataaa gcctataacc atgcgctatc caaggagaga agcaaggttg agaacatctt
    15721 tgccaaagta aaaacgttta aaatatcttc aacaacctat cgaaatcatc gtaaacgctt
    15781 cggattacga atgaatttga ttgctggtat tatcaatcat gaactaggat tctagttttg
    15841 caggaagtct attgaaatac taatcctaca cagactgatt ccaattgttt tttagatttc
    15901 aattttacca ttcttcatag tcaaaaccat cataatctgg atattgttct agcgacgttc
    15961 caaccgaacg tacgagataa gcttcttcgt cctctgtcta gatttctctc agcacttggc
    16021 attcaaaacg ccattcatca ccgaagtcga aaataaactt aaatttttgt ttgacactta
    16081 ggctatccag atagacattt tctgtgtaac gttcttcaac atcgtcacta acaaagctaa
    16141 gaaagtaaga atctgcatga ctccactcaa cattatccat gaaaaatgcg tgagcatgat
    16201 caattgcaaa atcaaaactc cataaaatca catctgctag ttccgctaac gtttttgttt
    16261 ttggaatcta tatatgtcgg tagcaacctt ttttaaattt gacggaaatg atccaagctt
    16321 ctacagatgc tggcttttca gcttctattt cttgttttac taattttaag tgtagcataa
    16381 tacctccaat tgctcatcga tagaattgct cttaggaaac attcactttc tgctatttta
    16441 tcataagttt gtctaactgt agcatttgaa accagataat tcttctgttt cacgcgaaac
    16501 accctgcgcc aagcaaggta ttcttgtttt tatactcaat gaaaatcaaa gagcaaacta
    16561 ggaagctagc tgcaggctgc tcaaaacact gttttgaggt tgtagatgga agctgacgtg
    16621 gtttgaagag attttcgaag agtatgaaga gtattaagtc gtataaatcg tcgacgctgt
    16681 cgcaatggta tgccactggt tagctgtagt tgctgcgaag tccttgtctg cgtagaagtc
    16741 agtaaatggt aggatttcaa cttccagctc gtcgatgcgg tcaagctggc cagccagata
    16801 aacctcgata cggctttctg ctcgtttgat gcgttgcaag agtccgccca tacggatgtc
    16861 aactgtatcc aaaccaaaga ccttgttttc tttcagccat tggtgactaa agagggcatg
    16921 gaagtcttca atttggcttc taagttctgg taattcttgt ctggcgattt gttgtaaact
    16981 ttctttatca tccgcttggt aggcctgacg aatgcgtcgt cccacatcta ctttgctact
    17041 taaaatagca ttcaactggg cctgagtttc aaagagataa gcatagtttc cagctttttc
    17101 tttaatgtca gcaatagttc ccgccgcctg agcgaagtgt ggcttgtcct gttcaggtgt
    17161 catgtgtcgg tcaagtatcg gacagagaac atcctgataa aagacatagc ggttgggatt
    17221 gatgccactg agattacctg gtaggtctgg taagaggttg gcaaggtcaa tctgcataaa
    17281 atcctcaacc gttagaccag tattggtctt gaaatgcgca gacaaactat ctaggtcatt
    17341 gcgatagctg agttctgccc agatttgcaa gcttggtagg atagagaact gggcagtttc
    17401 accaccattg tctccccaac ccgttacgat gacttcttta atctgattgg cacggcaggc
    17461 tttattagcc tcgatagcta ctagacggct aaaatggttg tgaggtgtaa agccaatcca
    17521 cttccaagct ccccctgcaa atgcaaggtc atggctaatc ttgtgatgat tgcggaaatt
    17581 acggttgtat ttttcctcgc tatcctgata ataatcccag taaaccagag tcacacggtc
    17641 tttgagacgg tctaggtaga cacgagtttc ctctggaatt tccacatcac ggtcgtactg
    17701 gccatccgct gacatgagtt tgaagaacat atcactccac atctggcagt ggaaaccata
    17761 tttgtcagca atatccagca cgcgctccaa gtgttggcac atgaggagac tacgattcac
    17821 aacaccgtcc agaatcaggt agcgtcccaa accaaccaag tgggcttcat ccatcccgat
    17881 attgaccttg cgagtcttca gtttagacaa cgtggcaaac atgctatcaa tcaggtcata
    17941 aaccttttct tcgccaatga gaagaatgtc ctctacatca cggagctctt gcacttcctt
    18001 gacaccccat ttgacgaagg ctgacaaatg gggcaaggtc tggatgcaag gcacaaaggt
    18061 catgtcaaac tgttgggcat aggcttcgat ttcctgcaac tcctcaactg aataagctcc
    18121 acggaaatag ccaaagtaag gttgcccttc aatctggtaa gtgtcttcca tgtaaagctc
    18181 aaaggttgag tagcccatga gagccaatat ctcaatcatc tgcttggcag aagcgacatt
    18241 tagcaccgca tttcgagaac agtcaaccat gtaagccaaa tcttcgtaag ctgcttgttc
    18301 ctcaatctct actttatcag cttctgctag aactgttacc aacaaggaca aggcacgata
    18361 aagttggtga ggtttgcggt aggtcaattg atagtgacca tcctcaccct tgatagagat
    18421 agaggcttgg tcagactgag cgactgacac ctcaacatct ggcagagaaa tgtgaccttt
    18481 taaaacctca atagcttgcg tttgtttggg actaagtcct gtaaatctta ccattgcttt
    18541 tcctcctgta gccagttgac aagggcaccg tagagattgg catctgcatg ataggtgcag
    18601 gcctggataa ctggtgcgac cgtgtattct tcgtaggtat cgacaaagtt atcaacagcc
    18661 ttcttaatac cttggataaa atctggattt tgactgatag agccacccag actgatgaca
    18721 tctggatcga tcagatactg gatattgagc aagccttgcg ccagattgcg gttcatgcgc
    18781 tcaatggctt cttgacaaag agcattacca gctgcggcct cttggtaaat cttgcgaccg
    18841 tcccaatcag tatgaccaga tttttcaatc acatatcgta ccatattccc agttgacgct
    18901 agttgcgacc agttattaag tttttcagca ggggcaaggg ttgtcatgta gccaaattct
    18961 ccacccagac cgtggcgacc tcgatgaagt ctaccattga tagtcatggc tccaccaatt
    19021 cctgtcccaa tcacgacaca ggctgcattt tcaagctctg gatgagctag tagttcactg
    19081 agtccaacgc agttggcatc attttctaaa tggacaggta gctgataaga gctaagcgcc
    19141 tcatgccaag aaaagccatg gatgtagggc accgcactga agccatcaat cacacctgtc
    19201 tcttgattga ctgcacctgg aacactcata gcaatcccac tgtaatcctg ttctgacaag
    19261 cgttgatcta gccacgctag taaatcctcc aagttttcag gcgttgaaat acttgtctta
    19321 tccagtattt tcccatcagg agtcagactg gcaaacttaa tcccagtccc tccgatatca
    19381 atcgttgcaa tggtcattgt ttttaccata aaaaggggcg aatcagcagt tagttcttac
    19441 tttttcgccc ctcctttctt ttgatgttta ctttttgaaa ttaaatttct tcttttttga
    19501 tgaattctgt acgaatctct tgtggagcca atagtcctga atgaactgga tatggtcgct
    19561 caagtaagtc aagaatggtt tgttgatgtt ctgatatgcg cacattttct tgactcatat
    19621 tatagtaacg gaggacatag ccttcttcat tttccgccac tttaaaggct gttggacaaa
    19681 cttgcggtat gctgagaaca gaatggctca agaggctacc agtcgcaacc acgcttcctt
    19741 cctgtctagc aagctgaagg ctggtaaacg gtgtctgcaa ggctttggca cgacgatagg
    19801 ctgagaagcg ttcttgggct tggtggcatt caagtgcaaa ctcgacttca aactcacgca
    19861 agcattgtgc ttctggcgtt gggaagtagc cccagtcacc tagctcacct gatgcacgca
    19921 aaatggtcac ggcaatggtg ttatccccaa ggatttcgta ttcattcaat cccttattgg
    19981 atacagtcac tcctttttca tcgtcataca gactgacaaa agcttgttga tgttgaggat
    20041 tttcccatga agctcctggt ttgtttggtc gtgtcaccac ctcatagatg ctttcagaat
    20101 cattgcttgg acgcgtgtta tgagtcttga ccaagagacg gatacggtga tccttggcag
    20161 tgttagtaaa gcgagtcttg aagcggattt gtggattgtc aacaaagaca gtaaactcag
    20221 tttccagagg aatgtttgtc aattcttctg accgtccagc ctcacgcttc ataaactcga
    20281 tgataccttt ttgctcttct tctagctttt catctgcact gacaggcacg gtcaattcat
    20341 gtttgagcaa aatcttagca tagcgagctg tgttttccaa gacctcgtag cccttaagct
    20401 ctgcaaagat tggctctgtt ccttttggtt ggaaatagat atactcgttt ccgatgtccc
    20461 cacggtcttc aaagcggata aagtcttcat aagcttcgtg agttgtcttg tcataaactg
    20521 tgatattgtc atctacactc accgttacga atggtgtatc aatcactccg ttttggtaaa
    20581 taccctcacg gtgttcttgt tttccttcca gcaattggaa ggttgtccaa gaaagcggtg
    20641 ctaggtgaac tggaatggtc acgcgcactt gtcgagcaat acgagcttgg cggaacttat
    20701 cttttggtaa atcgtactca aaattagctc cgaggtcttc gattgtagcc tctacaggac
    20761 gaccatccaa gtcctccaca cggtagcttg gcaagataag agcagccatc tttttgtagc
    20821 cttctgttgg gtgcaattcc ttgaaatcac aagtcgccac atcaatcact gtgctgacag
    20881 tatcgacctt atcatgcaag cctgtgttaa tgacagtaaa gagatagtca ctttgagcct
    20941 tatccgtagc aattttaccc ttccactcgt tgagcaagtt acttttaaca aagtttccta
    21001 cttggttgac cttggcaaaa cgcgtttcca tctcgcggtg aacttcgtcc acgctacagc
    21061 cacagatact atcatgtggc gcattctgca aaagtgtttt ccaagcatag gtcaactggt
    21121 ccttgtggtt gtgtccacca gtgataatag tcaaggattc taccacttgc tctaggaggt
    21181 tgctattttc ttggaaggct tgttttaggt aaatgcgaga tgaagaagtg ttggcaagtg
    21241 tgtaccagcc atctgtttcc tgactggtca actcgcctgt aacagttgat aagtgttcag
    21301 gaagcgcacc ttctacagct tgaacatatt catcaaaaga attatgaaca aagattacat
    21361 ccgggaagag ttcatttgcc acacgaatgg cttcgctcag atttttctgt acaggctggt
    21421 ggtcacagcc gttcatcatc aaccatcggt tggtcgaagc gtaggcacgc acatctgaca
    21481 atttttgttt ccagaaggtc aaggcctcat ctttgtcaac tggaatttca ttcccgttac
    21541 tgtaccagtt ggcaaagaga atacctaaaa cacgactacc atccacaccc tgccagtaca
    21601 tttttgaaaa ctgggatgta aactgctcat cttcaaggac ttggttgtca aatccaatcg
    21661 gcttcacacc acgaccaaag gcggtcacgt gaatgcctga tttttgaaga atttgaggcg
    21721 cttgtcccat atttccaaag gtatctggaa agtagccaat ctgagttgat ttaccccatt
    21781 tggcagcttc ttgttgacca atcaaggtat tgcggacatt ggcttcactt gaaatcaaat
    21841 aatcatcctg caagatgtaa aagggaccaa ttttaagctt gccctcgtca atgtagcgtt
    21901 ggaccttgtc gcgattttca gggcgaattt gtaagtagtc gtcaaggaca atagtttgtc
    21961 catccaagtg gaaactcttg aactcagggt cattttcaaa gagatcaaag agattgtcaa
    22021 acaattccac caactgcata cgatggcttt caaaaggcaa gtaccactca cggtcccagt
    22081 gactatgtga gataatatgt acaacaacat tttccatgaa gtaaaacctc attctaaatt
    22141 taaattttaa cgttttaaat gtaaacttgt gattctgata agaatcggtt gagctaatac
    22201 tcaacgaaaa tcaaagtgca aactaggaag ctagccgcag gttgctcaaa gcactgcttt
    22261 gaggttgtag ataaagctga cgttgtttga gagattttcg aagagtatta gcgaatatcc
    22321 aagtaatcca agaccaactc acagaacatc atgttagccc aggagaacca ttcacgagag
    22381 tagagggtcg gatcatctac gtggaagctt tcgtgcatga cacctgtacc accatcgcag
    22441 gcaaccagct gatccagcaa gaattttttc tctgccttat ctcttgttgt caatccttgg
    22501 atagaaaggg cgattggcca gatatagcga tagaaggtat gagaacttcc gagaccgcta
    22561 gcgtattctc cttggtagaa gtatggattt tcagagctca aaatggtacg acgagtagct
    22621 tgatacactt catcatcgac cgaacagtag cccagatagg gcgcagctag tagacttggt
    22681 acatttggat catccatgat gctggcattt cctaggccat ccacttcaaa ggcataaatc
    22741 ttttcaccct tactgttggt ggtgtaagca tagttttcaa ttccttcttg gatctcatcc
    22801 tgaagacgct tggcatcagc aataacactc tggctatcag ctaggtttaa tgctgcgaag
    22861 atttcttgca cataacccaa gactactaca gcaaacatat ttgacggaat caagtaacta
    22921 tactggcaac agtcatcact cggacgaaaa gctgaccaag tcatacctgt cactgcaaag
    22981 tcaggtccaa agccatcatt tactaaggtg ccgtatctcg gacaaaacga taaggagagt
    23041 tcttgtggtc ttgttcaact gtccatagat ggagaatttc cttagtcgct gcgacaaaag
    23101 tttcatcaaa ctgactagtc tcgccagtct ctttccagag gagataagcc aactgcaagg
    23161 gatagcaaag tgaatccacc tcatacttgc gctcccagat ccagccgtta aggtctgtgt
    23221 ggtcagtctc gtggtgccct ttacagttct cctcaatgtt gaaggagtta gcatagggat
    23281 ccttgagtac caaggtcatc tgacgtttga ccaaacctgc aatggtctga cgcaggaggg
    23341 catctctttt agctacatga aggtagggtc tgagttaggc tgtcgaatct cgaagccaca
    23401 tggcaggaat atccccagtc aagacaaaag ttgaaccatc ttctaagatt tcaaccgtat
    23461 tgtccaaggt atcggtgtag caacgctcga aaacatccac ccactctgga tggtccttag
    23521 cccgctctgc tacttcatct agccattctc taacaatttc tttcgaataa atcatcgtgc
    23581 aatttcctct ttcaaacaag tttcattttc agtatatagc ttttgagaca gaaaatacat
    23641 acacaaatga tagtcatttt tctacaaaat agttatcttt aaaactcctt ttctaaaggt
    23701 cctctttttc tgatataatg tagaaaaaca gctaaaggaa agactatgaa accactactt
    23761 gaaatcatcg atacccgctt tggaactacc aacaagcatg ccttttctcg gggaaatacc
    23821 ctgccataca caggcgtgcc ttttgggatg aattactttg tgccccagac cagtgaccag
    23881 gatggatctt ggttttttga tccgcatctg cctatctttc aggggattcg cttaactcac
    23941 cagcccagtc cttggattgg ggactactct tggctccttc tgacacctgt cacaggtcag
    24001 cttgggggag acagtctctt tcaccgccaa tcttcctatg atagggataa ggcctctttc
    24061 caacctcact atttgaagct cttttctctg cgttatcaga ttgaaaccca gctcacaccg
    24121 acttgctttt gcttctattc gtttgaagca aaagcaaggc aaagccctct ccctctatct
    24181 tcacgcagca gataaactga cagtagatca agtagataag cggactcttg ccctgcgaca
    24241 agaaggtaaa actgaaacta acaaaaattc gctaacgatg ttcactgccc tgcaaatgaa
    24301 cacggatatt cttgctatca gccaagaagc tggagactgg cgaattgact tagcaagtag
    24361 tcaaaccgag atgcaactag ccacttcttt catctctcct tctcaagctc taatcaatct
    24421 acctcaagaa gattttgata gctgtaaaac aaatgcccaa gcggattggg aaaatctcct
    24481 ccatcgtttt gacattatag agacaggaga ggctgaccga accttctttg accactgcct
    24541 ctacagactc ttcctcttcc cacagacttt ttatgaggtt gatgagtcag ggcaagccat
    24601 ccacatggat ctggctactg gtactgtcaa gcctggtgtc ctctttagca acaatggttt
    24661 ctggaatacc ttccgcacca ccttccccct ctttgccctc atcataccgg agcactatca
    24721 acgcttttta gaaggtttcc tcaatagcta ccgcgatact ggtttccttc caaaatggct
    24781 ggctccagat gaacggggta tgatgccagg tacactttta gacggtatta tcgcagatag
    24841 cgcctgcaag gacatgaccc ctgacctaga aggagaactc ttccaagcca tgctcgaaac
    24901 agccagcaaa gccgaccctc tcggaatcaa tggccgccac ggactagccc aataccaaga
    24961 actaggttac ctctctaccg accaccacga aagtgttagc catactctag actatgccta
    25021 tagtgacttt tgtatcgcca gctgtgccaa aaaactagag aacatagaaa tcgctgaaac
    25081 ctacaaggct gcttcacaaa attaccgcca gctatttgac gctgagacag gttacatgcg
    25141 agcacgagac aatcaaggaa actttcaccc tgacttctct ccttatagtt gggggcgaga
    25201 ctacgctgaa tgctctgcca ttcaagctac tttaggcgtt ctccacgaca tccctggctt
    25261 aatccaactt atgggtggaa aagaaacctt tagcaactat cttttgaaaa cctgtcaaga
    25321 tgctcccctc tttgaaacaa caggctatgg ttacgaaatt cacgaaatga gcgagatggc
    25381 tactgctcct tttggacaaa tagccatttc caaccagcct agtttccaca ttccttatct
    25441 attccgctac agcgattacc ctgactacac tgcccttctt atcaagacgc tccgtcagaa
    25501 agcttttcac ccaagttggg aagcctatcc tggagatgaa gacaatggta gtctctctgc
    25561 ttggtacatc tggtcagctc tcggatttta tctaacctgt ccaggaaaac caagctatga
    25621 cctcggaatc cctctctttg accatctacg agtctaccta gctaaagaag ataaatggct
    25681 ggatatccat actaaacaaa accacaacca ttttaacttt gtcaaagaat gccgactgga
    25741 caaaacactc gtatcaacta ttcaacacca agacctctta aaagctgaac aactaacttt
    25801 caccctcagc tggttaccaa gtcagccgtc aacttcctga aatgcaaaaa tctcctagca
    25861 ggctttcctg ctaggagatt ttcttatgag aggtatttgt ttaatactca atgaaaatca
    25921 aagagcaaac taggaagcta gccgtagact gtacttgagt acggcaaggc gaagctaacg
    25981 cggtttgaag agattttcga agagtttaag ctttaaaaat cggatttatt attcgataat
    26041 tatcaaacaa tctaccaatt aagcttcttc gtcttcttta cgacgacggc ctgcaagacc
    26101 aaggtaaggc acttgcggct gctactacca tagctacagt agaatctgct gtacctgtat
    26161 ttggcaactc tttagcgact gtacgcgcgt ttgctgctgc ttggttggca tttgctgctt
    26221 gagcagtagc tggagctaca gctggtgttt gagcagcttg gtccttagct gggcttgtat
    26281 ggtcagttgc tggagaaact ttagccatga agtcttcgat acgtttaacc attgcatcca
    26341 cttcatcttg gcttgctttc ggatctgcaa atactttctt agcgtctgcc aataagtcag
    26401 tcgcttcttt tgcagtttct gcatcaagct tagctgattc ttggataatc aattcatcta
    26461 attgatggat agcaccttaa acacaagaaa ggtacagaga tgcaaaacca ttatactaca
    26521 aaaggcaaac atttgacaat cgatagccgt cgcttaatcg aaagatggaa aaaagaaatg
    26581 aattatgaag atattttatg aagatatttt atctcgtttc aactaaaata tgagcttgat
    26641 caatcagctg tccaccaaca gtcaggttca gataaaaatc caagatcttg tcggcagcaa
    26701 aatacagagt tggtatgctc aagtcttttt tgctttcccc tgcttggaat tgaaggactt
    26761 gaatctcgtc ctgataggcg acaccatgga cacctgtccc cggttgaatc gaaatcttag
    26821 cctctaaaga ggagctactt tcactacgtt caatcctaaa atgaagagtc tctccctttg
    26881 taacagctag gcttttttct gcaaatgcta gttcctgaac aacttctttt tttgataatc
    26941 caggagtttt ataaagggaa atcttggtca atacaggaat agattgtgcc tctgtaatca
    27001 tcacgcgcac cttctgtgcc tctactagcg gacctcgcaa gaggcgctta tgaccaactg
    27061 tgaagcccct gccgaattct tgccagacgt catccacctc tacttgcaca taaaaagtag
    27121 cgattcgttg ccctagcttc aaatcttctc ttaactcaat tacatcaaaa gttttaggag
    27181 aacctaagtc gagttctaac tggattggca agcctacatc gcttgcccca gagctagttt
    27241 taaggccatc tgtcagatga taacaagcaa agtctacgga aagagctgaa ccagatatct
    27301 cagctcccag agccaaatct tttttataga gctcattacg ataggccgca aattcataaa
    27361 ggcgttcaac atcctttgca tcaaagagcc catctttatt cggcggaata ttaagcagga
    27421 gtggagttcc tctcccaacc gagtgaaagt agatttctac caattcctcg agagacttag
    27481 gatactgatc ctcatggtag aaccagcccg gccggataga gacatctgcc tcaccaattg
    27541 aaaaaatcgt acccgaagga tctccgtgct gaagatagtc cagctctgct tctgttccta
    27601 gtttgtcagg attcaccttt tgccataggg gatcacctgc atagcctcgt tcattaccaa
    27661 tccagcgaat gctagtgcct tctgttgaaa aaatcaagca atcgccctgc aggtcacgaa
    27721 tggtttcaaa ccatgtctca aattcataat tgaccttttg cgcgccctct cctctggcac
    27781 catccatcca aacctcagca aatttccctc catttccata ggcaggattt gataagattt
    27841 ccttcagctg agccagataa taggcattgt agtccgcttc tcggtccaca tgatagaggg
    27901 gactatgggc atcccacggt gacaggtaga cccccatatc catatcaaac tctgtggcag
    27961 cttgagatac ttcaagaagc aagtcgccct ttcctcttct ccaaggactg accttaatcg
    28021 aataatctgt gtgagctgtc ggataaagga caaagccatc gtggtgcttg accaccaaaa
    28081 tcaacttttt gaagcccgtt tccttgagca cacgaaccca ctcacgtgcg tctaactgtg
    28141 tcgggttaaa gcgttcagga tcctcctgac ctgttcccca ttcctgatta taaaaagtat
    28201 taggtccaaa atggataaag gctactagtt catcctctaa atacgctaac tggacctgac
    28261 taggcaaggg gctatgcggt tttatttctc ttaccatact acttcctatc tacattttct
    28321 taactttttg gcatgtactt gcaattctgt taacgctagt ggatttacca agttttcaaa
    28381 tcgaagacga agggcatagg tttccacctt gtcaaattca aaacgaagct cttcatcctt
    28441 gtcacctgac acttttcgga tagttgatac cggtcgccaa ttctcctctt gtttgagagc
    28501 agaatcctta tccaaatggt ttggagtccg aggcaaagta ggctcattcc ctatgtaata
    28561 atcaataaag ctaggctcca ccgccacgta ttcttgattc tcaacataat acaaggtcag
    28621 gttatccaca aatcgcggtt ttaaaatccc tacatttcca aaaagaatac ccacgctggc
    28681 ttgctctgac ttggtaatcc aagtattggc tgtcgatttc ttccgagaaa tgaccttgtc
    28741 attgaggtaa gaggcagggt gattcgattc tgagtgagaa gcaaagacca gaggtaggtt
    28801 ggagcctgtc cactgattgg aaataacttc cccatctaca ctagcatctg tcacatgaat
    28861 ggtgactgtt gctggtaact tacagcccac tacttgtcct gtgaacacac attctcctac
    28921 ctgagcatag acttggggtt cgagttcatc ctaagttacc ttggccgtat ctcgtctgcc
    28981 atctgataag actagcttaa ctcggtctgg taaatgtggg gcttccttga caagcgtcca
    29041 aaccctctca gactcaatag cacaaatccc ttgaacacaa acctgagcag aagcctctaa
    29101 atccagaccc tctagctgac cagataccgt aaactcatga aatcttgcca aatcttcttc
    29161 aggaatctcc tcccagacaa ccttgactcg ttttgcaccg cctgactcat agtctaccaa
    29221 gactgaaaat ggcaactgtg gataagttcc cttatctgta tacaagcgaa gtggtcttac
    29281 aaaaactgcc tgccctagtg aggtattttc tgcaatctgc aaatgagttt gataggtctt
    29341 cccttgataa atggcatgaa tagccaagtc gcctgcagac aagcaatgaa gtactccctg
    29401 cttgataatg gcgtgggcac taccactcgt ctcccaaaac acttcactat tccctacctt
    29461 gttcacagga ttatccacag tttgtggata aagtccaata gctggggaag ctccttcttg
    29521 caaacctgcc tgatcgtcca ctcgaatctc caacaagcgc tgatttttca ctggctggca
    29581 atcaaaagcc tctcccacta agagatcaaa acttgctggc tctagccctc tggcactagc
    29641 ttttactctt acttgacctg cctgctccaa gctctgagcc tgataacgtt cacgactggc
    29701 ctgcctgccg ttgtccacac ccacaatacg agctggtcct tcaattttga aatgaagctg
    29761 attggaagca ctcggcaccc aatttccatc cttgtccaat acatcaaaat agagatagag
    29821 gaggtcttgc ccatctggct ctagttgtgt tctctcggca tgtaacccaa ttttagcagg
    29881 cttacccgca gtcaccaccc tatcttctgc cacaatctga ccttgacggt cataggccac
    29941 aacacgcaat tctcccggtt gataagccaa acgccattcg agatagagtt ggtcagaacc
    30001 ttctccctct tgatattttc tgccatctga agtccatttc tcttgaaaag tcttcctgcc
    30061 ttgagatttt ccattgagaa atagctctac tggaccagca tttgaataca ctcgaaccgg
    30121 gatatcccca tacttatcca cagcttgttg ataactcttg tggatttccc aattccagtg
    30181 gggcaggata tgaaccacgg gatgctgatc taggtccaac cactgacttt gatagagata
    30241 ataatcattt ttaggaatcc tcgccgtgtc cacaatccca aaataagaac tcttgacagg
    30301 cgtgtcattt tgattgtgcc aaggggtcgg ctcaccgata tagtccactc ctgtccagat
    30361 aaactgacct gcgtagtcta gcctatttct atctgctatc aaagaagccg tcgctgtctt
    30421 cccccaagga actcgatcat tgccatagtc tgactgttca aaattccgca cgcgacgatt
    30481 atccccaacc tattccttat ctgggcgaaa atagctatca cacgttcggg tagccgatga
    30541 ggtttcagac ccgtaaagtc gccacttggg atgtcttttg cgaatcccgt caatattatc
    30601 ttccgagtaa ttcaacccca ccacatccag caaatcagca atcttttcat gacctccaga
    30661 accatctcca aagcgaaatt gatccattcc catggtcaca aaacggctat catcaacctc
    30721 cttaaccctt tctagcaagc gtttgacagt tttcaatgaa tgaacatcgc tatttgcttc
    30781 gctgacttca tttcccaaag accacataaa aatcgctgga ttgttcttgc cacgctcaat
    30841 catagtgcgc aaatcgtaat ccgaccagaa atcgcctgct ttcgcttctg gatgagtcgc
    30901 ttcttcctca aaaaagcgac catagtcata ttctttcttg cctccatacc agatatcaaa
    30961 ggcttcttct tggatgagta gacccatttt ggcaaccaca tccagcaaaa tactactggc
    31021 tggattatgc gtgattcgaa tcgcattgac gcccatttcc ttcatctggc gcaagcgtct
    31081 ctcagcagct gacctgtttt ccatagttcc caacgctccg tagtcatggc gcaaacaaac
    31141 cccatgaatc ttcaaccagc gaccatttag aaagaagccc ttatctgctt gccaatccat
    31201 atagcggtaa ccaaaattct cctcttcttc atcagctaaa atgccatttt tgtaaaggcg
    31261 agtcttcaat tggtaaaggt gaggggaatc aatatcccaa agcaaaggtt ggaaaattga
    31321 tatggcttgt tggaaatgat gtttgtcccc agcttcaatc actacagagt ctgtcgcctg
    31381 ccagtctgaa acctgttgtc catcatacca gatactctgt tctaaataca ccgacacaga
    31441 ctgaggccca tcatttgaaa ccttgctttc aagctgggtt tccacccatc catctctttg
    31501 ttcctttagc ttgggacttt ctatcttaat cccatacaaa tccagatgaa ctgcatctgt
    31561 catcaacaat tttacttctc ggtaaatacc gctaccagag taccaacgac tgctaggttg
    31621 ctgattttcc acaaaaaccg caagctggtt ggccgtccca tcatttctta gataaggcgt
    31681 gataacatat gaaaaaggta tatagccatt gggataatag cccagcactt gcccgttgat
    31741 atagacttgg gcattcatgt aaactccatc aaacaacaaa cgcaccgata caagactggc
    31801 atcttcttcc aagtaaaact gcgtccggta ccaggcctga cccccattta gctgaccacc
    31861 ctcattttgc gctggcgaat actggtcaaa atcattgtaa atactccagt catgtggtac
    31921 ttgaatcgac tgccaatttt ccctctgaaa atccggcgcc aaggcctctt ctttccctac
    31981 ctcttgacta aaaaaccagt gatttcgtaa aacttcttct cttctcatac aagcattcct
    32041 ctttaaacga ctcgatttac ttgactatag cacaaaacaa aagcgctttc aagatttcct
    32101 ctatcactcc ctaaatactc agaaaagatt ctataatttg tggaaaagtc tgaaaatcac
    32161 tccatattca agcaaactat cattttcaag aaataaggtc aaaccttaca agagagcaaa
    32221 aaacacctct ctgaatgttc attccagaga gatgttcctt ttgtcttaac tattgtaaat
    32281 cgactgtcta aagtcatctg aatctttgag ataagcttta taaatcgctt ttttcagttt
    32341 ttgaactgga gtttcgataa actcaaactt ttgagccgtg gtattgcctg cttttatctg
    32401 ggctagttca gctaaaacag ctttctgcat caattctttt aacttctgac ttgtcagact
    32461 tatttgctga ccttcatatt ggattgtcaa aggtttcaat tgattgagcc tatctactct
    32521 ttccttgaac tgtgcttttt taaactcagc atagctctta ccattcaaaa ttttattgaa
    32581 aatgtaagta tcagatagag gcttgttctc agactctgct acttgcttgt attgatttga
    32641 tacataaggt acaaatcctt cataatagcc caaagcagcc atcaattcaa atgcttgttt
    32701 tctaaaggtg atgtccccac tcataccaga gtcattttga ctaacaccat aaatggtatc
    32761 aaacatatcc actaaataat atccattagc ttttacatca cctgttgcat aaaatccatt
    32821 tatgatataa cgattaacta aaatattatt atcaatcaag ctattgatat ccgttagttt
    32881 ttccgcttct gccaatgtga tttccgagat tttttcactc ttgtgcgtag ctttaaccgc
    32941 tgaatttgta tatgttactg tcgctctagg tcccttcgac gcaatcggtg ttattttttt
    33001 gaaatattta gttttatctt cagctgtaag ttgttttgtt gcttccgctt ctaaataatc
    33061 taaactatat aacacatcaa aacttccatg catataagat ttcaagtctg catctgtttt
    33121 gaatctatct ggtgttttgt tgtagaagcc atttttctta ctttcatcgt aaacgaagtt
    33181 taagttaaaa tatgtatctt tttctggtgt gtaagaattt tcaaagatac ctcgagcata
    33241 aaactccgca gctgtaccat ctcgacgacc atgattatta aacagcactg ttctgtctaa
    33301 taaatgcgtc atttcgtgag agtaagtcgc tgagcctcta tcatccagaa ctctatctat
    33361 gaagtaacgg acacctactc cattggcttc tgcacctaca ttttgcgatg gtgaatacag
    33421 gcctagaggt gtcataaagt ctttaacccc tttatctgct gttggtcctg attctttaga
    33481 ccatgttgtc cctattccag cagacgtatc cgccgtgtat tttttcatcg tgtctacaat
    33541 cactctattt gtaactaatt tagaacgatt ttcttctttt gtaattctgt ataaagtatc
    33601 aacgtatgca gcctgtcttg tcgcagtcaa ttctatcaat gctttaactt tttctaattc
    33661 ttctttatac ttaactggat ttgttttctc taaagaagta tccatatacg ttccgatatt
    33721 tccgtaggtc accgtcgcta tgttagttat agcatacacg cttggttctt taatatttac
    33781 caaacctaat aatatagcta cattttgttg tcttctactt tcaatttgaa gattttcagc
    33841 tccatatttc tcaggaggtg tagttaattt tgtatataat tctacttttt cgtcaggttt
    33901 ctgtttcgaa ggcttttcaa ctacaatagc tttagtcgct ttcttcaacc acgtatcgcc
    33961 atccatatta gtgaatgtag ttctgttgta atctaggaac tctaataatg ttggtttatc
    34021 tgtaatttta ccaaagtatt tctcaaatgt ttttggacta ttggttaatc ttaattcatc
    34081 ataactcata gacccaaggt atgttaacca atctaaagaa gtaaggtctt ttttaccgaa
    34141 cgagcttgga ttataagcta gaatatcacg gatattggta tctccaaaat caatattata
    34201 aaaacgattg atataggata accctagtaa tattttctct ttattagctt caatatcacc
    34261 ttttactttt tctctatttt gttgattgtc acctaaaata ctcaaggtat gcgccgcaac
    34321 ttttttcaaa ctagcttcta aatcggtttt agtcgcatcg agtgtttctt taatagataa
    34381 tttttcaaga tattcttttc gtagaatttc ttttacttct tcatcagtta tcgccggatt
    34441 agtttttcgt aattcttttc gttttaagaa taaatctcga tttatttcta tatctgatgg
    34501 agctaactgc gcttttaact tctcatttgt caacaagtct acatttctca tctccgcagt
    34561 agcttccgtt acgtttactg cattttctaa ttcgctatta attgggagta aatgaggttt
    34621 gtcttcttta gtgccaacca agattacttt ttggcgcata gctttagttg tttcagtctt
    34681 ctctactgga tttgttaact ctcctgtctc cggattaact tcataagttt tagtgacggt
    34741 tgtttcccct tgttcacctg catcctcaac ctcttctttt cctttcggaa gttcagggtt
    34801 atcttttctc aactcagtga tttctatagg tgacactatc ttttccacat ttccaacttt
    34861 tactattttg tctttagctg gaatattttc tattgtagtt tcttctgaga tagctcctgt
    34921 ttcttgattt actgtgtatt ttgtagttga tactgtacgc cctttttcac ctggtgtttc
    34981 ttcttgttgc acattgtaac ttaaatctgg cgatgcttta taaactgtct taaaaggaat
    35041 ttcttgtgat tgaactgttg gttttgttcc tactgccgtt attttcgctt gcatttcttt
    35101 ggctactttt gttgaaactt ctggctccgt caagtctcct gtttgtgcat ttactttata
    35161 aacacgaata gtagtcgttt cttcgtcctg accttgattt ctgacttctt tgacaccttt
    35221 atcaagtgac tcatccgcga caaactgttc acctcttttg gttgttgagg ttgtttcttc
    35281 tacatttcca accttaacaa ctctatctac tggatgtttt tctatctttg ttgaagtgtt
    35341 ttctactatt ttcccagtac tttcatcaaa actgtaagaa gtagttgtca cttccttacc
    35401 attttcgcct gctacttcta cttgttgctc tttgtaattt aaagctggcg atgctgtata
    35461 gactgtttta tagtccaata ctttttcttt cgttactgga ctcgggacag ttggttgcac
    35521 ttgtgaatct gactgctctt ggggagctga gggttcaggc tgaacagctg gagctggttc
    35581 gtttccttga cttgggttga cctctggaga tggagccgtt tgttctggtt gtttttgggg
    35641 ttcttgtggg gcagattcac cagcatcttt tgccccctca actggattct ccagctggtt
    35701 ctcctcaccc ttttgttccg caggagattg atcttcctct cgtcctgatc ccacggctgg
    35761 gcttgctagc tctggttgct tcggctcggc ttcgggtttg tcaggtgttt gtttctcgcc
    35821 cggcgtttct tctgctcctg gtcttggttg tcctattcca gcagctggtt ttgtctctgt
    35881 ttcattctct actattggtt ttttctcaat tttttcaggt tgaactggtt taacttcctc
    35941 tggctctgga gttacaggtt gtgttggttt tggtgcaact tcttccttag tcccaactgc
    36001 aatcaccttg ttctccggct cttttgtgac tatattttct ataactttgc tagatttttc
    36061 cccgttaacg atagtgactt ccgtatagat ggtgcgttca ccaacaacac cttcttgaac
    36121 aactttagtt tgccctttag ctaagcttgc atcttcttgt tctatcgttt ggaaagcaat
    36181 ctcctctgta gtaactagca attctggttt ctctactgtg gcatttaaca cgccttcctc
    36241 aggacttggt ttataatcac tattattctc tgctttcggt tgttctactt tgggatttcc
    36301 tgcaatttct tccttagtcc ctataggcac aatttcatca ggagcttgtt tgcttacagg
    36361 agcttcaaca attttctcaa ctgcgtagga tggttgagga gattgcacaa aatcttcagt
    36421 cgagctaaaa tgagatgcag tctgtggtac aatcttctta gattgaggtt ctgaaccgtc
    36481 ctccttttta gataatgctg gcgactctac cttatcaaca gaaagttcct tgttactact
    36541 gtctcttacc aaataatatc ccgtaaattc atatccttgg actctttcag gacttggtag
    36601 aaactgacct tctacccttt taacaagggc cggttgcaat tctaccagat tttcgaaagc
    36661 agagatggat gctccccatc caccaacagc aaagactgtc acaaggaagt aagacgctcc
    36721 cctttttctc ttgattaaag tgaaggaaag caataataat cctgctccca ggataaacgt
    36781 cccatcatta gaaaaaagac ctgtttctgg taatcttgta gccaattttc gatagacaaa
    36841 gtagtattct tttccctctt ttacctcaat cttattttct tcaaaccatt gcaactcaga
    36901 tttcagcttt tcagataaat cctgctcatc caaataatga cttgaaatta gtgttgaact
    36961 cgtttcggta gcctgtacag gctgagcatc cataccagca aaaaataaac tcgttcctag
    37021 caagaccgaa caagctccta ttgcatattt cctcaaagaa aaacgctgct ttcgctcaaa
    37081 ttgaaattct ttcatcccat ctcccatcat tcattattac tgtatattta gtatatcaga
    37141 aatagtttgt attcacaaat ctttctagtt attcccttat cattccaagt taagggcaac
    37201 aacatacaat aatttttatt taatactctt cgaaaatctc ttcaaaccac gtcagcttcc
    37261 atctgcaacc tcaaaacagt gttttgagca acctgcggct agcttcctag tttgctcttt
    37321 gattttcatt gagtataaat gtatatcaat gttctttgtt tttcttaaca aacgcaacgc
    37381 aaaaagagcc tgttgccaag ctctttagtc tattatttct tctcagcgcg gagggctgac
    37441 aagatttgtg tacggatatc atccacacca tttggcgtat ttggtaaaaa gatcgtttga
    37501 tttcctttag aagcaaaggt attcaaggta tccaagtact ggttggtcaa gagaatggac
    37561 atgatttgtt cttctgtcat accaacattg gcttccttga gttcggtgat agactctgcc
    37621 aatccatcca caatcgcctt acgttgttgg gcaatcccca caccatgaag acgatctttt
    37681 tctgcttcgg cttcagctgc agtgacgatt ttaatcttgt cggcttctgc caattcttgc
    37741 gctgcaaccc gcttacgttg cgctgcattg atttcattca tggattgctt aacttctgca
    37801 tctggttcga ccttggtaat caaggttttc acgataatgt agccataagt tgtcatttct
    37861 tctgctactt ggtgttgaac ttcaagggca atctcatctt ttttctcaaa caattcatcc
    37921 aaagttaatt tgggaacaga agagcgaagg gcgtcttcaa tataagattt aatctgagat
    37981 tctggacgca tgagtttata gtaggcatct gtcacgctct gctcattgac acggtactga
    38041 gtcgctacat tcatcataac gaacacattg tccttggtct tagtctcaac cacaatatcg
    38101 ctttgcaaca aacgcaactg aatccgcgct gcaatcgagt cgatcccaaa aggcaagcga
    38161 atatgaatac cgctattggc aaccttttgg tatttcccaa agcgttcaat aatcgccacc
    38221 gactgctgac gaaccacata aactgtgctc agtgtgacta tcagcaatag gaacacacaa
    38281 acaatcagaa aaatcatgaa aaatattgcc ataatggaac ctccacaagt atttttctag
    38341 tattatagca catttaaaga agactgtgca gtttttactg cgatttttcc tgaaatgtca
    38401 ataattagag gtgaagccaa atttcaagtt actaatctct ttttttcact gcattaactt
    38461 ctatagaatc ttcatccata gtcagagaat gacttgcctt aatttttctc tcgtgctata
    38521 ctatttatga aattaatgaa taggagatat ttcatgaaat cagcaaaaac tactgttaca
    38581 atcctttctg cacttgcatc tgtcgtctta ttatctagtt gtgcaacaaa gtctacagaa
    38641 acacagacaa gcaataagag ctcatctgat aatcagatta caatgacata tgaccaacta
    38701 cggtcaagag aaaatactat gtcaaccctt tggtattaaa aatcagctga aaccaaagcc
    38761 ttgtatctac aaggttataa tgttgccaca gatcgtctaa aggaattact gaaaacagaa
    38821 tcagacaagc cttattcaat cgttttgaac ttagatgaaa cagtcttaga taatagtcct
    38881 tatcaagttc aaaatatcaa agacggaaca gcattcacac ctgaaaattg ggatatttgg
    38941 gttcaaaaag ctgcagcaaa agccgtccca ggagctaagg agtttcttca atttgccaat
    39001 caaaacggca tccaaattta ctatatttct gaccgctcag ttaatcaaat agatgctacg
    39061 attaaaaatc tagaaaacga aggaatccct gtacaagggc gtgatcacct catgctctta
    39121 gaaagtggtg taaaatccaa agaagggcgt cgccaagcag ttcaagagaa aactaatcta
    39181 gtattactat ttggtgataa cctcgtagac tttgcagatt tttcgaagac ttctgaatct
    39241 gaccgtgata aacaacttga agaattgcaa aaagaattcg gtgaaaaatt catcatcttc
    39301 ccaaattcaa tgtacggatc atgggaaaca actgtctacg ctggcaataa attggatgct
    39361 aaaggtcaag tggaagaacg ccaaaaggct ttgcaaggtt ttaataaata aaacaaataa
    39421 gctgattcta tataaactaa ggctaactta caatcttcaa aaagtggata ggaaggaatt
    39481 ctgataatca gaaaactttc ctatccactt tttgaattga tataacatca agcttttata
    39541 catctgatac tatatgtttt ttgattttaa agactttttg cctatcccct atatttcaag
    39601 aattaagcaa tcttgatgat ctaaatttgt tgtgatataa tatttttgtc atcggttacc
    39661 gattacgttc ctatgggttc gtgagaggag gtgaaactaa tgagccttat catagagctc
    39721 gctcttacta ttatagcgga tgttatagct ggaattatct tgtatttcgt ctgcagatgg
    39781 ctagatagta aggagtagac cgactgacta gcctatcaac acccgttaaa tcgctaagat
    39841 acgtcaaaaa agcccttaac tacggcaata gttaagggct ttggtgttct aatgaacctt
    39901 atcaattaac tatattctag catataaacc ccaagatttc aagcattaag taaggttgat
    39961 ggtctaaatt tattgtggta tactattttt gtcatcggtt accgattacg ttccttacgg
    40021 ttcgtgagag gaggtgaaac taatgaacct tatcatagag ctcgctctta ctattatagc
    40081 ggacgtcatc gcaggaatta tcttgtattt cgtctgcaaa tgactagatg gtaagaagta
    40141 gaccgactga ctagcctatc aacacccgtt aaatcgctaa gatacgtcaa aaaagccctt
    40201 aactacggca atagttaggg gctttggtgt tctaatgaac cttgcttatc aagtttattc
    40261 taacatacag gcccagatat ttcaagagtt ttatttattt tttacagttc tgtaaggtct
    40321 atagtgaagt tagccatcta gtacccaaaa accgactagc tcttatgaac tagccggttt
    40381 tctcatcaat gtgccaacat ttcttgggcg atttcttggc cagataggtt atctgggtag
    40441 taggttggcc agttatccat ttcttcaaag agggcttctt ggcttgtgcc tccaaagaag
    40501 atatggaaat gttctgcctt aactggggcg atattgtggt cactaaactg aacatatttg
    40561 aattgtccag cgtcagcatc tgtggcttca aagaggaagc gaacaccacg attgcctttc
    40621 ttgtaagtca agattttctt accaacatac ttgtaggtga atttcttgct ttgtccacct
    40681 tgaacaaatt ccatagtatt atcagtaata ttaatcttag tcacatctgt ctgatagcct
    40741 tttgtatagt aagccttgta ctcagcctgg gtcatcttac cagtcaactt agccttgtag
    40801 tcaaagactt ggtcaaacgt gccatcttca aggaaaggat aaactgattg ccagttacct
    40861 acatagtcac tcaaggtgcg atccttgaca gctgcatcct caaagtaacc attttgaact
    40921 gtcttggtat cctctgcctt ttcaggctcg attgctgggc cttcttggtc cgttgtttgt
    40981 ttcagagcct tgaggttttt ctccatcacg gaaatgtagt tttcgccagc cttggtatcc
    41041 tcttctgtca gactttccaa aggattgagg acatctgttt tgacacctgc ttcttttgaa
    41101 agtgtgttag caagggcttg tgaagcattt tcttcaaagt agatataggc aatcttattt
    41161 ttcttgacgt actctgtcaa ttccgccaag cgagcagctg atggctctgc atctggagag
    41221 aggcctgaaa ttgcgacttg tttgagtcca tagtctaagg caaggtagtt aaaggctgcg
    41281 tgttgagtca caaagctctt ttgtttggct tgaaacaagc cttctgcata agccttatcc
    41341 aaggcttgca atttttcaat ataggcagca gcattcttct caaaggtctc ttttttatca
    41401 ggataatctg ctgacaagct atcacggata tgctctacta gtttaatggc acgaactggt
    41461 gataaccaaa catggggatc gaactcatgg tgatggcctt cttctccatg gtcatggtct
    41521 ccctcttctt cctcaccacc tggtaagagc aacatatccc ctgttgcctt gatggttttg
    41581 acctttttct tatccaaagt atctagcaat ttaggtaccc atgtttccat gttttcattt
    41641 tcataaacaa aggtgtctgc gtcttggatt ttggcaactg ccttggcaga cggttcatat
    41701 tcatggggtt ctgtaccagc accgattagg agttctacat tagcagtatc tcctgcaact
    41761 tgcttggtaa attcatagac agggtaaaag gttgtcacga tatttagttt gccatctgcc
    41821 tgcttttgat tggaacaagc cactaaaaac aaggcacata gactggctag caataagcta
    41881 atttttttca tgatattctc ctatttgata aaacgtctta ctaaactgat tagcaagaaa
    41941 acagttacaa aaataatggt aatacttgca cttgcaggtg tttctgcata gtaggaaatg
    42001 taaagccctg ctaccattcc caaaaatcca atagcactgg caagcagcat aaccgattta
    42061 aagtttttcc ccagacgcag ggcaatacta gctggcaaga ccatgatagt cgataccaga
    42121 agagctcccg cagctggaat cataagggca atggccaccc ctgtcaccat gttaaaaaga
    42181 atggacatgg tacgaactgg caagccatcc acaaaggccg tatcttcgtc aaaagttaag
    42241 atatacatag gacgaagaaa gagaaaggtc aaaatcaaaa caaccgccgc aatgacaaag
    42301 agggaaatga cctgttcttc actgatagtc acgatcgaac caaagagata ttggtccaaa
    42361 ctcattgaac tagagctttt acccttactc atgacaatca gagaaacagc cagacctgtt
    42421 gacatgagaa tagctgtccc gatttccata aagctcttgt aaaccgtacg gagatactcc
    42481 agaaagaccg ccgcaatcaa gacaatagca atcgtagaaa cagttggcga aatccccaaa
    42541 accaacccaa aagctacacc tgaaagtgag acatgactga gggtatcact catcaaactc
    42601 tgacgacgca agatgaggaa ggttccaaga actggcgaga aaagactcat ggcaataaca
    42661 gccagaaagg cacgctgcat aaagtcataa gataataaac taagcatggc ccacctcctg
    42721 atcattctca tgaacgttga aacaacgcca tggcgagtct tggttacgaa ctagatgaat
    42781 attgcgatcc gcatagtcct tcacttcttc agggtcatgg gtaatcatca aaacagcctt
    42841 gccatgatga tgggcgctgt ggtgcatgag ttcgtaaaat tcatttttac ttcctgcatc
    42901 catacccgtt gtcggctcat ctaggataaa cacatctggg tcagaagcaa acatacgcgc
    42961 aatcaccgct cgctgctttt gccctccaga aagagacccc aagcgtttgt ctcgatgttc
    43021 ccacatgcca actgagtcca gactggcctt gatatgctcc tcatcatgag cattcaaacg
    43081 acggaaccat ccttttctcg gatagcgacc cgacttgaca aattcataga ccgtacttgg
    43141 aaaaccagca ttaaaactgg caatttgttg aggaagatag gctattctca atttcttacc
    43201 ttgcgtattt gtctttgaaa tagtcacctt tccaatgcgt ggttgcagaa ttccaagact
    43261 ggccttgatg agcgtcgtct tagccgctcc attttcccca gtcaaggtaa caaattcccc
    43321 actatcaaca ctataattga tatgttcaag aacaggctcc ttatcataat agaaggacaa
    43381 atcctctacc gtaatatatc tcattatttg atttctccta ctaaagcagt caaaaactgc
    43441 tgaatcactt tttgttcatt tggagtaaac tgagtcgcca cttgttcata ggttaaaagt
    43501 gtatgctcat gatgatggtg gtgctcctca gcgattggac gagccaagtc agtcaactga
    43561 taaaaaatca cacgcgcatc tttagaatct ttagatgttt ccaacatccc ttccttgacc
    43621 aaagacttaa tggccttggt aactgccgcc tgactgacat tgagacgacg ggccaattct
    43681 gaatttgtta aagattcctc tgacaagagc ataaggatat gctcctgggt atttgtcaga
    43741 gccacctcgc tagtgcaatg acctattagg atttcatgct gattttccgc ctgcaaaatc
    43801 acctcattca aaaaagcatc gatatccttt gctagctgtc tcatatctga ctcctttcct
    43861 tttagacttc tcttttttaa gagaaaaata ctattctttg acattttatt taccagttaa
    43921 ttatatcaca agcaaaaaaa gagtcaagaa aaaacgtgaa aactagtttc attcttgaac
    43981 tcttctatat tatattatct attgaaattc tttgacatct ccatcataag tcgcccaatc
    44041 tttgctgaaa aagcgctcat tcagatgata agtcggagct ggtgtgggat tggataggaa
    44101 aggatcaact gccttgtcaa aagccaacca acccaaccaa ccaaggtgaa tggtgtcctt
    44161 cataaagaaa ggctccccgc cgtccttaga aaaatctgct atattggtaa aaccttgact
    44221 ttctaactgg tagcgaatct tctgcaccgt ttgttggtac atatcctctc gtagaccagc
    44281 atagtccatc cattttttat taacaggtgg aatgataaaa atcgggttta ccttagattt
    44341 agaaaactgt gttaaaacca actgcaagtc attatactct ggcgacttga gataggtaaa
    44401 gcttttctga gaatccttta atttcttcaa atccttcttg atctgctcat tatagaaata
    44461 attttccatt cccagatcat tattggaagt atttttttca gcatctgctt tgacaacatc
    44521 tcctattgct tgataagaaa actggtctgg caagattttt aaatacttag ctacatgctt
    44581 atcgtagtta acatagcctc taaccgaaaa ctgaccaaaa aaggaggctt ggcgttcatt
    44641 aaaacgagcc aataattcaa tcatttcatt gtctgctgtc gacaattctt ctttacttgc
    44701 caacttctga accaggtcct tcatagctac gtttgggaac tgttgcagta agcgagtcgc
    44761 tgcatattga ctagcctgat ccccagattg atgtttcaga aaactagtca actggtctcc
    44821 attaaaatac tgctggaagg ctgctggctc atagccattt ttactgaacc actgaggtga
    44881 gataacatac acaacttgtt tattctccag ctgtggtagc atctgttgca ttccaaaata
    44941 ttggttaagc gatgcagctc ccccctgtcc taaaagataa ggacggtagg aacgattgta
    45001 tttctcagct aataccgcag gatgagcacc gtcaaaacga agccattcac tagagccaaa
    45061 gaagggaaca aaacgcacat ttggatcaga tagtgctctg actttttgac ttcgctcctt
    45121 aaaactatcg atagtagtag ccaccgctga acgcttttca gctcctagat tatgacgcat
    45181 ctcagtagga taaaagaaaa tgagcagaaa aaccaacaaa ccagcgatca agaccggtcc
    45241 gaagatcatc cataagcgtt taagcatttt gtagctccac aataccagct atgattttat
    45301 tagctgtatt ccagtcgtca cgaccaaact ctgttacagg gacacgaatg tcaaaacggt
    45361 tctcaatctc cacaatcaac tcaaccgttc ccatactatc caagacacct gcatcaaaaa
    45421 gatcttcatc catcatgtca gaaacatctt ccataaacaa ctcatcaata atttcgataa
    45481 cttctgattt gatatccata ttttatttcc ttttattttt taaaccatag attattcaag
    45541 aatccagaaa agattaagaa tgacaacatg acaacatgga aagtgacaac cataccaagc
    45601 aactgaatcc agcgattctc aggtagggca gccttccctg cttttttccg ttccttattg
    45661 agcgtttttt tcttgcgaac ccaggcatca ttgataacca agcctagtcc atgaaagagt
    45721 ccataggcga tatagtacca ggtcacgcca tgccaaaatc ccataatcag catatttaca
    45781 atgtaggcca tgcttgaggt tacattacga tttttaaaga ctttctttct ggttaacacc
    45841 atcaccattc gcataaagac aaagtcgcgg aaccagaagg acagactcat atgccagcga
    45901 ttccaaaact cctttaaatc ccttgataaa aagggcttgt taaagttgat agggctacgg
    45961 attcccatca agtttgagat ggccaaagca aacatagaat aacctgcaaa gtcaaagaag
    46021 agctccagac caaaagtata cataactgcc aaggcataga gattaaagaa gccacctgac
    46081 tgcaaggcta aattcttcag aggaggtagt aaggtctctc ctaaaacatg agctaggata
    46141 aacttataca aaaagccccg catgatatag cggacagatt catccagcat atccatcaac
    46201 tcatctcgct caggaatggc ctgataattt tcattaaatc gcttaaagcg atcgattgga
    46261 ccactcgaga aagttggcat gaatagaagg aaacggagga atttccagag ggtaaaatcc
    46321 ttaatcactc catctctcag ctcgatgatc atcccaaccg aacgaaaggt caggtaagaa
    46381 attcccaaga acccaagcaa agactgcgtt ccattgatag ctggttgcac cttgacaaag
    46441 ataatcggaa gtagggacag aaaactaact aagtagaaga cccacttgcc atccttgctt
    46501 tttcgataat gcttgtagaa aagcaggatc aatatttccc agcaaaggta aatacccaag
    46561 gcagctagtt gattggtctt tccacccacc aacatggtga caataaagaa gagacttacc
    46621 aacacttcat accaggcaaa gcgtttcttg aaaaagaggc ctataaagat gggcaagatt
    46681 gcagcaatca cataaacaaa atactgagga ttgccatatg gctctaaatg aggaagctgt
    46741 tgaaaaaact ccatcatctc ttattcacct cgttaatcaa tcctttgatg tcaatctttc
    46801 catttggagt tagtggcaaa ctgtctcggt aaaggaattt agatggcatc atgtaggaca
    46861 tcatgatgtc tgtcaggtct tccttgatgg ccttggtaat atcgatatct cgctcaaact
    46921 gctcacgaac accgtctttt aagatgacat aagccaatag attttgtacc ttgtggtcct
    46981 tgttatagcg cggtactgcg acagcagatt cgataaagcg agacttgttg aggttttgag
    47041 agacatcttc taactcaatg cggtaaccgt taaacttaat ctggaagttc atgcgtccgc
    47101 cgtagagaag caagccctca tctgtcatgg ttcccacatc gcctgtgtga taggctggca
    47161 gaccttcaaa ctcaaagaag gcttctgctg ttttttcagg attgttcata taaccttttg
    47221 aaacagctgg cccagaaaca atgatttctc cctgttcgcc atttggcagt ttatttcctt
    47281 cctcgtcaat aataaaggtt ggagaatcag ccttggtata gccgattggt aggcgtttga
    47341 gagtcgctaa catctcgtct gtcacggcaa ctgctgacag agctactgtc gcttctgttg
    47401 ggccgtaagc attgatgata cgggcatttg ggaaacgctc gcgcagtttt tgagctgttt
    47461 tgaccgtcaa ttcttcacca tcaaagtaga aatgcgtgat tccaggcatt ttctcactgt
    47521 tgaagtattc agacaacatg gccatatctg caaaggatgg tgttgatgtc cagatagcga
    47581 ttggcaatga aaagatagcc gcaaagagtt gcttaaagtc ctgagtgatg actgaaggaa
    47641 gagtgaaaag cgtaccacca agtgccaagg tcggtgccca atacatgaca gacaagtcaa
    47701 aagaataagg tggctgtgcc agcatttgcg gacgactcgg tgtcgcaaat tccttatccg
    47761 taatcatcca gtttgtaaag ctgaggagat tatcatgtga aatctgcact cccttaggct
    47821 taccagtcgt accagaagta aagataatgt agtaattatc atctcccttg actggatgcg
    47881 tgatttcata gttgttccct tgggcaaagg cttcttgaac ctgagctaga tttatcattg
    47941 gtgtagaaac ctgctccaag ggaaaggctg aaatggcaat aatcaagctt ggctctgcta
    48001 cttctaaaat agctgaaact cgctccaagg ccgaatggct atcaattgga atgtaggcat
    48061 gacctgactt agtcagcgct acaaaggttg ccaacatttc atattcttgg ccaccaaaaa
    48121 caaccacagg agacttctca ggcaagccta tttggtcaat gactgcagcc aaactatccg
    48181 aatcagcctt taaatcgcca taagtgtgtc tctgccccaa aacattatag acaggatagc
    48241 taggctgtgt ctgagcaaaa tgctcaatgg tttcaatcat atctgctatt ggtttatttg
    48301 acacaatagg gattctcctt caagttaaaa ttcattatag ataaagcttc cttgaccctg
    48361 accaagatag ctaaagaagt aaagcagccc tagaaagata agaaaataca aggctgtccg
    48421 accaagaaag aggtacaatt cttttctctg tttcatcaag aaaaaccatt catttctgta
    48481 atttttcgct aaaataagag tgattcttac tagcttattt ttctaccatt gtaccacttt
    48541 atatagtatc ttttcaattg tttaccgtat gtttccaata gatttcagct tattttaagg
    48601 attatgcggt ttttctatgt ctatttcaaa agaaaaaagc ctgagatttt catctcaagc
    48661 tctatcaaaa taattgtttt ctaatactca atgaaaatca aagagcaaac taggaagcta
    48721 gccgcaagct gtacttgagt acggtaaggc gacgctgacg tggtttgaag agattttcga
    48781 agagtataaa ctagaaaagt gagaatacaa gcacggccaa ggctgctccg ataacagggc
    48841 ctacaacagg aatccaagcg taagaccagt ctccgtctcc cttgttagga attggcaaga
    48901 tgctgtgcat gatacgaggt ccaaggtcac gagctgggtt caaggcataa cctgttgtcc
    48961 cacctagtga tagaccgata ccgacaatca aagttcccac tgcaaaggtt ccgatacctg
    49021 cctgaaaatc gtaaagaccc aaagcaaaga ttgtcaacac caaaacaaaa gttccaagga
    49081 tttcgctaat caagtttgat acagtatcct tgatggctgg tccagtactg aaggttgcca
    49141 ggatattgcc tgcattttct tctacctcat aatgcggttt gaattgcaac caaaccaaaa
    49201 tctgacccag catagcccct gcgaactggg ctaagatata aggcaaaacg gaagcccaag
    49261 gcaagtcacc ttttaaagct acaccaactg tcacagctgg atttaaatga gctgggctga
    49321 gttttccaga tacaaatact gcaaccgcaa ctgcaatccc ccaacccata gtaatcacaa
    49381 tccaacctgc actgttgctc ttggtttttg gaagaaccac acctgcaaca acaccatttc
    49441 ctagaagaat caggattaaa gtccctaaaa attctccaaa taattcactc atcatttttc
    49501 tgtctccatt aaaaaagggg cgggcgacaa ggattgctac cctccacctc ttttattttt
    49561 tcttaatttt ttaattctgc taaatcgttg ttagcaagag ctgcttcgac atcaacacgg
    49621 taagttgctt tttcttcttc tgtccagtca tagaatcgtc ccatttcatc caaaactggt
    49681 tcaacgatac tatccaagct atcacgcata aagagcatgt gattggtacg acgaagaagg
    49741 aagtcaactg gactaagagt caactcattg cgcattgcat agtgaaggga caaggtgtct
    49801 gccaagctaa gacctggtgc ttgttccaag ctgtgagcaa gtgcaaagac cttcggtgca
    49861 tttgaaccgt aaagatttgc taggtaatga gcttccttgc tatccaaacc acgtgaaact
    49921 ccaagttgcg caaaggcttc gatttctgaa tccacatttg ctgggttcaa ttctccacct
    49981 gaaacagggt aagtcttaga gttgatgagt ttaaagctgc ggtcaaattc tgctttgagg
    50041 atgtcaacca cgcgctccat agctccttca gccatcttac ggtagtctgt gattttacca
    50101 ccagcaagag tcaaaagacc attgtcatca cggtccaagc tagacccacg agaaactgca
    50161 gatggatcca aatgtttctc agatgtgcta ctttcaagct tgctgacagc agactcaaca
    50221 tcttcacgtg ttttttcttt ggagagataa gattcaacag tcgcaatcaa gttgtcaaag
    50281 ctttcatcac tgatggtacc gttatttcca ccattatagt cagaggcact gttccctgca
    50341 atcaatggac gaagacctgc ccagctgctt tcgatatcat caatggtgat gttggattct
    50401 gggaagcggt tgttgacaat gccaagtaga taatctacat cttcttgagt tacttttgga
    50461 tgctccaaat cacctgtgta gtctgtatca gttgtaccaa agtaagtctt gttttcacgt
    50521 gggagaacaa agaccatacg accgtcaccc aaacctgtgt cgaagtaaac tggctgtgaa
    50581 accttgattt tgcttgaatc cactaccaag tgaactccct tagttggacg tatttgtgag
    50641 aattgcgttc ccttattaga caaattgcgt actttatcgc tccaaggacc tgttgtattg
    50701 ataaccagac gagccttgat ttcaaagact tggtctgtca agagatcacg agctacaaca
    50761 cctgtaatct tgccactttc gtcaaagagg aagccttctg ctttaacgtg gtttgcaatg
    50821 agagcaccgt cttggttggc acgtttgatg ttttcaatca caagacgcgc atcgttgtta
    50881 cggaagtcaa ggtaaacccc acctcctacc aaaccttctt tcttcaagtt tggctggcgt
    50941 tccaagactt cttccttgct caagaccttg tttgcagctg gtgtattgtt gacacctgcc
    51001 aaaaggtcat acaaatccat agctacttta agacggaaaa ggctaaaggt agctccatct
    51061 tcttcataaa ctggcaaaag cattgggtct ggttttggaa tgtgtggtgc gatttgttga
    51121 accactgcac gttcagaaac cgtatctgag accacttcta cgtcgaattg tttgaggtaa
    51181 cgcagacctc cgtgaaccaa ttttgttgaa cggctggatg ttccttctgc gaagtcctgc
    51241 atttcaatca aaccagtctc aagaccgcta gctgccgcct gcaaggctac accagcccct
    51301 gtgattcctc caccgataat caagaggtcc agggtacgtt cctgcatttt tttaattgac
    51361 aattcacgtg ttttctttga aaattccata cttacacact ttctaaataa atcgctttat
    51421 tagtcgtcta cttccgcaaa gacttgcgtt gcttttacag ccttcttcca gcccttgtag
    51481 agttgttcct tgcgagattc gttcatagat ggttcaaaga gttctcctgt ctcattcaag
    51541 agtttcaact catccaaatc cttccaatag cccaccgaca aacctgctag gaaggctgcc
    51601 cctagagctg ttgtttccaa gtttttagcg cgtgcgatgt cgattcccaa aatgtcagct
    51661 tggaactgca tgaggaagtt gttcatagct gctccaccat ccaccttcaa tacttgaata
    51721 gctgtctgcg catccacttg catggtgtcg atgatgtcac gtacttgata agcgatagat
    51781 tgcaaagtcg ccttgataaa gtcttctttg cttgttccac gagtcaaacc aaagacggaa
    51841 ccacgagcat tttggttcca gtatggagct cctagacctg taaaggctgg cacgacataa
    51901 acttcatcat cattgtgaga atcacgagcg tatttttcag attctggtga attttcaacc
    51961 atgcgaagac cgtcacgaat ccactgaata gcacttcctg cgatgaatat tgaaccttcc
    52021 aaggcatagt aaaccttgcc gttgattccg taaccaatcg ttgtcaagag gttgttttca
    52081 gacaactgca tttcttcccc agtattcatg atgataaaag aacctgttcc ataagtattt
    52141 ttaaccatac caggttcaaa agccaactgt ccaaagaggg ctgcttgttg gtccccagcc
    52201 atacctgaga ttggcacttg tccaccgtag aaatggaatg gagctgtctt accgtaaatt
    52261 tcagagttag aacgaacttc tggaagcata gccttaggaa tgttgaggat ttccaaaatc
    52321 tcgtcatccc atttgagttc cttaatgtta taaagcatgg tacgggctgc atttgagtag
    52381 tccgtcacgt gagccgcacc gtcagtcaat ttccaaacca accaagtatc gatggtacca
    52441 aagagcaatt ctcctttttc tgctcgctct tgagcgccct ctacatggtc caaaatccaa
    52501 cgaaccttgg tagcagagaa gtaagcatca atgatcaaac cagtcttttc atggaatttt
    52561 tccacataac cttgactttt tagttgctca gccaaaggtg ctgtctggcg tgactgccaa
    52621 acgatagcgt tgtagatagg gagccctgtt tttttatccc agacgaccgt tgtttcacgc
    52681 tggttggtaa tcccgattgc ttcgatttga tttggcttga caccactttc gatgaaagct
    52741 ccagcgataa ctgactgaac agagttccaa atttcattgg cattgtgctc aacccaacct
    52801 gcctgaggga aaatctgggt aaactctttt tgactcgagc taaccttttc cccttttttg
    52861 ttgaaaatga tggcacgaga acttgtagtt ccctggtcaa tggccatgat gtatttttct
    52921 tgtgacatgt actgtcctcc tgataaagat cttgaggtgt ttcctcttta cacttactag
    52981 tatacaaaat aaagcgcttt cttatttatc aacttttttt aatttttaaa aaaatgtgag
    53041 gagattgtgt aaatttcaca aaaaagacct ggaacaacca agccttttaa gtgaataata
    53101 actgacgaat ccctgccaaa tcctccatat ccaagtcatt ttttaaataa tagactggtg
    53161 tctgttcctt cttatgaata gggttattgg taaccagcaa atcataatgc cgactagggt
    53221 cataagcttc aatggtaata aaacgattgt attccaaata ccgtttcaaa atggctgcca
    53281 tccttgaaaa gacaagaaaa cctgatgtca aatccaaacc aatccgcata tgctggccat
    53341 cattttcagc catatactct atcaactgaa gccattccca gagaatcttc ttatctaagt
    53401 ctgtcccctg ttgaaaagtg ggcaaggtat gaaaaatctc ctctgccatt cctctaaaat
    53461 catgttccat cagtaaatat ggatggcgat tctctaactg gtacttgtag cggtcctgta
    53521 aaatatagcc cttatagaga tagacttgag cacaaagctg actgagttca taggtaacgt
    53581 gatcctctgt ataatcacct agcaactcct ccttcttcat tttttgaatc aattgcgtca
    53641 gcaaatcggc taactgccct ccaaaaccaa ggatatactc catagtatga agaggaagaa
    53701 tgcgatgaga taggaggaaa gagaagaata tcatcatctc accatcctca gttcctagag
    53761 gaaggtgttg cccagcaaaa aaggacggag cctttctcag caaacgaagg tagaaaatat
    53821 tgtcaaaata ccctcgcatt ttctcttcta tgacctgaaa ctgacaggcg ttgacccgaa
    53881 gacgttgttg actgatgtga gaccagagaa ccaagtccaa tttctgcccc gcagacaaac
    53941 ttgcaccgca gatttcctct aaattggcaa tctcctgttt tctctctggt ttctgcatgt
    54001 gaccttccca ttcctgactc gaccagacct ttcggaaaag acagaaatag aaatagcgaa
    54061 tctgatgttc tggacctcgc caacgtccat tttggatgga taaatcaaat tctgacaaaa
    54121 tctgatttaa accagccaag tgacgaccaa gcgtagcctc gctaatcacc aattcttgag
    54181 ccagctgatg ggctaaaaac tgttggtggc agagaagata aaccaaaatt tggtatttaa
    54241 cagcactctc caaaaacaag ctccgaatat ctctcccctt ggtagctgca ccgatagaca
    54301 gacgcagatt ttcatcttct gagtgaatag tcagttctaa gccactatcc aaaaccttgt
    54361 cattgagcag ggtgacatat ttggttaggg ttgcttttga aaatcctgtt tcttccatta
    54421 cagccttgac ggtcgtctga gactcttgta atagaaagga aaggattgaa aattgaccac
    54481 actcggcttt ctccatcaaa tctcctaaat acatttgtta cccctttcat tttctacctt
    54541 aagcatagca taaatcttac aaatgctgaa ataatctgtt tctcttttta ttttcatgct
    54601 gatttcctgg tccattatcc tgaaaatcag taaacacacg gctccccctt tgggcatttt
    54661 tatgctaaaa tagtagctat ggataaaatt attaaaacta tatcagaaag cggagccttt
    54721 cgtgcttttg tccttgatag cacggaaacc gtccgcactg ctcaagaaaa acatcaaacc
    54781 caagctagct caactgtagc gcttggtcga actcttatcg ccagccagat tctcgcagcc
    54841 aatgaaaaag gaaataccaa acttacagtt aaggtgttgg gatctagctc tctaggttct
    54901 atcatcaccg tcgctgatac caaggggaat gtcaaaggtt acgttcaaaa tcctggtgtt
    54961 gacattaaaa agaccgcaac tggtgaagtt ctagtcggac ctgttgttgg aaatgggcaa
    55021 ttcctcgtta tcacagacta cggcattgga aatccttata cttccttgac cccactcatc
    55081 tctggagaga ttggggaaga ccttgctttc tacctaacag aaagccaaca aaccccttct
    55141 gcagtcggcc tcaatgtcct tttggacgaa gaagacaagg tcaaggttgc aggtggtttc
    55201 ctagttcaag tcttgccggg agccaaggaa gaagagattg ctcgctttga aaaacgcatc
    55261 caagaaatgc cagctatctc tactcttctc gaaagcgacg accatatcga agccctcctc
    55321 aaggctatct acggggacga agcctacaag cgtctttctg aagaagaaat ccgtttccaa
    55381 tgtgactgta gccatgaacg ctttatgaac gctcttgcca gccttccaag ctcagactta
    55441 caggaaatga aagaggaaga ccacggggca gaaatcactt gtcaattctg ccaaactact
    55501 tacaactttg atgaaaagga cctggaggaa ctcattcgtg acaaatctta atacaccttt
    55561 tatgattggc aatattgaga ttcccaatcg taccgtttta gcgcctatgg ctggcgtgac
    55621 caactcagcc tttcgtacca tcgcaaaaga gctcggagct ggactcgttg taatggaaat
    55681 ggtctctgac aagggaattc aatacaacaa cgaaaaaacc ctgcacatgc ttcatatcga
    55741 tgagggcgaa aaccctgtct ctatccaact ttttggtagc gatgaagaca gcctagcacg
    55801 cgcagcagaa ttcatccaag aaaacaccaa gaccgatatc gtcgatatca acatgggctg
    55861 ccctgtcaac aaaatcgtga agaacgaagc tggtgctatg tggctcaagg atccagacaa
    55921 gatttactcc atcatcaaca aggtccaatc tgtccttgat attccactta ctgtcaaaat
    55981 gcgtaccggc tgggcgaatc catctcttgc agtagaaaat gccctcgctg ctgaagcagc
    56041 aggtgtttct gcccttgcca tgcatggccg tactcgcgaa caaatgtata ctggccacgc
    56101 agaccttgag accctttaca aggttgccca agctctaacc aagattccat tcatcgccaa
    56161 cggtgatatc cgtactgtcc aagaagccaa gcaacgcatc gaagaagttg gtgctgacgc
    56221 agtcatgatt ggccgagctg ccatgggaaa tccttacctc ttcaaccaaa tcaaccatta
    56281 ctttgaaaca ggagaaatcc tacctgattt gacctttgaa gacaagatga agatcgccta
    56341 cgaacacttg aaacgattga ttaacctcaa aggagaaaac gtcgcagttc gtgaattccg
    56401 cggtctcgct cctcactacc tccgtggaac atctggcgct gccaaactcc gtggagccat
    56461 ttcccaagct agcaccctag cagagattga aggcctcctg caattggata aaacttaaat
    56521 acgacaataa aaacccgtaa ctcatgaagt ttacgggttt tattgattgt tgacactgga
    56581 agcctattgt tgaatcaagg aaacgctaga gacagctcca tctgcacctg ttgtaatctg
    56641 aatcactttc ccatcaccta ctttgacatt atacttacca tcatcaagtg tgtaagaata
    56701 acctttgata gagtagtttt ctttcttccc atcaacagtt tctacagtga actggccatc
    56761 tgatgaaacc gtgacggttt cgccgttagc tcccttccag ttacctgctg tagctgaaaa
    56821 atctccatct accatggtta aaacactctt gtagcgtttg ttgtgttccg cttgcttatc
    56881 ctgaagcttg cggtcagttg ttgggtcata ggttgactgg ttagactggg cttgagaatg
    56941 ttgttgagtt gaaggagttt gttgactgga atcttcttgt ccttgtcttg attctggtgc
    57001 cgaagatgtt tgtgttgctt gtgattgatt agtagccatc tctgactgat cagaagatac
    57061 tttcgacttt tctgatgaga ttgaacttga ggacttctga attttatttt ccttgctcga
    57121 agaagctact ttagaactag aagattgact tgtttcagta gcttcttttt tatttccaca
    57181 agctcccaaa agcaaggtgg aaaccaatac aatcgctacc attaatttga tataggtttt
    57241 ctttttcatt tttctaatca tttgtaatat tttagaaata ttaggtaata ttattgtaat
    57301 attttgcgca aaaagtggca attattttct aaattcgttt aaaattttta ttttttcccc
    57361 acatttagtc ctcccactat tctattcgta atagaaagag gctgggacaa aatagttctc
    57421 gaccacaaaa aagctagaga ttcccaattg cggaactcta gctttttaat tttgagtcgt
    57481 tctcttgttg tattttagga ggttattggc cataagtacc aatcccatgt caattctcac
    57541 ttgacgcttc cctctcagat gacatctctt gtaacccaaa gaagccttta tctgcccaaa
    57601 gacaggttcc acatcaatct tgcgttgagc gaaaatctgt ctaccttggg gagataaaag
    57661 cgc
//
LOCUS       DAVDHZ010000008        55712 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000008 DAVDHZ010000000
VERSION     DAVDHZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55712
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.008"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(128..1000)
                     /locus_tag="VUR46_000630"
     CDS             complement(128..1000)
                     /locus_tag="VUR46_000630"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET5456103.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1236..2546
                     /locus_tag="VUR46_000631"
     CDS             1236..2546
                     /locus_tag="VUR46_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET5456104.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(2912..3106)
                     /locus_tag="VUR46_000632"
     CDS             complement(2912..3106)
                     /locus_tag="VUR46_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5456105.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(3566..4294)
                     /locus_tag="VUR46_000633"
     CDS             complement(3566..4294)
                     /locus_tag="VUR46_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5456106.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQYYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            4452..5862
                     /locus_tag="VUR46_000634"
                     /pseudo
     CDS             4452..5862
                     /locus_tag="VUR46_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            5880..7175
                     /locus_tag="VUR46_000635"
     CDS             5880..7175
                     /locus_tag="VUR46_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5456107.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYIFAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFTLMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            7180..7488
                     /locus_tag="VUR46_000636"
     CDS             7180..7488
                     /locus_tag="VUR46_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5456108.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTINMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            7485..7793
                     /locus_tag="VUR46_000637"
     CDS             7485..7793
                     /locus_tag="VUR46_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5456109.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(8714..11365)
                     /gene="adhE"
                     /locus_tag="VUR46_000638"
                     /gene_synonym="adhC"
     CDS             complement(8714..11365)
                     /gene="adhE"
                     /locus_tag="VUR46_000638"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET5456110.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWISQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGHNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVKKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(11665..12075)
                     /locus_tag="VUR46_000639"
     CDS             complement(11665..12075)
                     /locus_tag="VUR46_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456111.1"
                     /translation="MENLKSFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     ILKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(12062..12505)
                     /locus_tag="VUR46_000640"
     CDS             complement(12062..12505)
                     /locus_tag="VUR46_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET5456112.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYQRVQEGCKVWLERLEKESEDGKS"
     gene            complement(12552..12851)
                     /gene="yajC"
                     /locus_tag="VUR46_000641"
     CDS             complement(12552..12851)
                     /gene="yajC"
                     /locus_tag="VUR46_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET5456113.1"
                     /translation="MNPNYTFLIMLALMVGLIFFTQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(12968..14944)
                     /gene="tkt"
                     /locus_tag="VUR46_000642"
     CDS             complement(12968..14944)
                     /gene="tkt"
                     /locus_tag="VUR46_000642"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET5456114.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLR
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFVQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSIPSTDVFDKQDAAYKEEILPNAVRRRVAIEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            complement(15058..16149)
                     /gene="ulaG"
                     /locus_tag="VUR46_000643"
     CDS             complement(15058..16149)
                     /gene="ulaG"
                     /locus_tag="VUR46_000643"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET5456115.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKVTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(16282..17934)
                     /locus_tag="VUR46_000644"
     CDS             complement(16282..17934)
                     /locus_tag="VUR46_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5456116.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVV"
     gene            complement(18113..18817)
                     /locus_tag="VUR46_000645"
     CDS             complement(18113..18817)
                     /locus_tag="VUR46_000645"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET5456117.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(18819..19682)
                     /locus_tag="VUR46_000646"
     CDS             complement(18819..19682)
                     /locus_tag="VUR46_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET5456118.1"
                     /translation="MVRPIGIYEKAIPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKAPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(19686..20351)
                     /locus_tag="VUR46_000647"
     CDS             complement(19686..20351)
                     /locus_tag="VUR46_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET5456119.1"
                     /translation="MTKRIPNLQVALDYSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     IKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            complement(20368..20853)
                     /locus_tag="VUR46_000648"
     CDS             complement(20368..20853)
                     /locus_tag="VUR46_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5456120.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(20929..21210)
                     /locus_tag="VUR46_000649"
     CDS             complement(20929..21210)
                     /locus_tag="VUR46_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5456121.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(21233..22690)
                     /locus_tag="VUR46_000650"
     CDS             complement(21233..22690)
                     /locus_tag="VUR46_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5456122.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKSTVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            complement(22821..23444)
                     /locus_tag="VUR46_000651"
     CDS             complement(22821..23444)
                     /locus_tag="VUR46_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET5456123.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(23495..24481)
                     /locus_tag="VUR46_000652"
     CDS             complement(23495..24481)
                     /locus_tag="VUR46_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET5456124.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(24500..25324)
                     /locus_tag="VUR46_000653"
     CDS             complement(24500..25324)
                     /locus_tag="VUR46_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET5456125.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQTQKDLENRKRKAKKKAQKTK"
     gene            complement(25299..25670)
                     /gene="rnpA"
                     /locus_tag="VUR46_000654"
     CDS             complement(25299..25670)
                     /gene="rnpA"
                     /locus_tag="VUR46_000654"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET5456126.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGGLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(25819..27009)
                     /locus_tag="VUR46_000655"
     CDS             complement(25819..27009)
                     /locus_tag="VUR46_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET5456127.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPKKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEVAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(27060..28013)
                     /locus_tag="VUR46_000656"
     CDS             complement(27060..28013)
                     /locus_tag="VUR46_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5456128.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(28074..28661)
                     /locus_tag="VUR46_000657"
                     /pseudo
     CDS             complement(28074..28661)
                     /locus_tag="VUR46_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(28798..29211)
                     /locus_tag="VUR46_000658"
     CDS             complement(28798..29211)
                     /locus_tag="VUR46_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET5456129.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(29189..29650)
                     /locus_tag="VUR46_000659"
     CDS             complement(29189..29650)
                     /locus_tag="VUR46_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET5456130.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVESNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(29613..29873)
                     /locus_tag="VUR46_000660"
     CDS             complement(29613..29873)
                     /locus_tag="VUR46_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456131.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(29878..30282)
                     /locus_tag="VUR46_000661"
     CDS             complement(29878..30282)
                     /locus_tag="VUR46_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET5456132.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQMISNGGQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(30275..30601)
                     /gene="comGC"
                     /locus_tag="VUR46_000662"
     CDS             complement(30275..30601)
                     /gene="comGC"
                     /locus_tag="VUR46_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET5456133.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVYD"
     gene            complement(30603..31619)
                     /locus_tag="VUR46_000663"
     CDS             complement(30603..31619)
                     /locus_tag="VUR46_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET5456134.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGESFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(31567..32508)
                     /locus_tag="VUR46_000664"
     CDS             complement(31567..32508)
                     /locus_tag="VUR46_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET5456135.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAVKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(32584..32949)
                     /locus_tag="VUR46_000665"
     CDS             complement(32584..32949)
                     /locus_tag="VUR46_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET5456136.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(33100..34157)
                     /locus_tag="VUR46_000666"
                     /pseudo
     CDS             complement(33100..34157)
                     /locus_tag="VUR46_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
     gene            complement(34320..35471)
                     /gene="nagA"
                     /locus_tag="VUR46_000667"
     CDS             complement(34320..35471)
                     /gene="nagA"
                     /locus_tag="VUR46_000667"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET5456137.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHAEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(35624..37441)
                     /locus_tag="VUR46_000668"
     CDS             complement(35624..37441)
                     /locus_tag="VUR46_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET5456138.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFLSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLVALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYTHTILVASTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(37542..38684)
                     /gene="tgt"
                     /locus_tag="VUR46_000669"
     CDS             complement(37542..38684)
                     /gene="tgt"
                     /locus_tag="VUR46_000669"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET5456139.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            38814..39671
                     /locus_tag="VUR46_000670"
     CDS             38814..39671
                     /locus_tag="VUR46_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET5456140.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLALSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCNKIMFYRA
                     VLARKRPKA"
     gene            complement(39699..40342)
                     /gene="pcp"
                     /locus_tag="VUR46_000671"
                     /pseudo
     CDS             complement(39699..40342)
                     /gene="pcp"
                     /locus_tag="VUR46_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(40345..40755)
                     /locus_tag="VUR46_000672"
                     /pseudo
     CDS             complement(40345..40755)
                     /locus_tag="VUR46_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(40957..42099)
                     /locus_tag="VUR46_000673"
     CDS             complement(40957..42099)
                     /locus_tag="VUR46_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET5456141.1"
                     /translation="MNKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSVVAEEAPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(42229..42885)
                     /locus_tag="VUR46_000674"
     CDS             complement(42229..42885)
                     /locus_tag="VUR46_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5456142.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSMAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLNKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGKHRIQALADISRIFEAERQKDCVSFVTET
                     "
     gene            complement(42889..44169)
                     /locus_tag="VUR46_000675"
     CDS             complement(42889..44169)
                     /locus_tag="VUR46_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET5456143.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTSMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            complement(44230..45714)
                     /locus_tag="VUR46_000676"
     CDS             complement(44230..45714)
                     /locus_tag="VUR46_000676"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET5456144.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELNYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCESYS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(45790..47067)
                     /locus_tag="VUR46_000677"
     CDS             complement(45790..47067)
                     /locus_tag="VUR46_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET5456145.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(47329..47805)
                     /locus_tag="VUR46_000678"
     CDS             complement(47329..47805)
                     /locus_tag="VUR46_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456146.1"
                     /translation="METRNEKFRRLSEARMTKVFSILNILRNQSDKSKYSFSEADIKE
                     LFGALEQKGEEIKEFFTSPITIKTVNLKQEFNYSSTDTSNDKEVYFKKLSTARVEKIF
                     SLMNLLTNLSNKSNYSYNDWEIEELFTAYDEEVKKCKVFFEEKRTVFKYSEQAIKY"
     gene            47959..48240
                     /locus_tag="VUR46_000679"
     CDS             47959..48240
                     /locus_tag="VUR46_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456147.1"
                     /translation="MFKELIEFVNSSTEGQFKAFQVKANAITGDVIISQNVTPITDAL
                     KNRLGLKTVQTSLARKLAYASTRRHYKDGTTMMEDILAGKTRRHANSYI"
     gene            48302..48544
                     /locus_tag="VUR46_000680"
     CDS             48302..48544
                     /locus_tag="VUR46_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456148.1"
                     /translation="MKSLYKYLFYLFFIGFAGTLCYVLLLTNAFSPIFEAATILMEII
                     VVIFLIICIDLIASPTGSAEENIKNENVKSNNPCEE"
     gene            48507..49871
                     /locus_tag="VUR46_000681"
     CDS             48507..49871
                     /locus_tag="VUR46_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HET5456149.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNITITRLSIQVFLFLLLVSSWLA
                     AIPFIARLVFSMFFISLLFLVERFFHSDVIEKLRNKLNIREALFYMLISLTLYDDIDN
                     EVVDTAVLYFDVSENDKVIICVPLFGNRYLKTLKNLEEYLCPTLGLSLIFKKEEIDKI
                     VYVLGKIEEIEQYVFNTNTLTREFFKDIPSPIIKLSNTQQFSLKSNTNIGIYGRTGTG
                     KTIALQWYLFNALAKGCGTVDGTYLGIVDGKGADLYALGKLLEEEIGNQVTVGTSPTS
                     LAKLSREFVEIMNERFEVIKQNSSLNADAYDLGMIPNFLFVDELASIRDSCCGSSKQA
                     KELWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGGPGADR
                     LKMAFSMCELENVPTVSDRKGEALFYADGLNSVEPVLTIVPFVDVKTKQEFLQIVKNI
                     LPNY"
     gene            49969..50283
                     /locus_tag="VUR46_000682"
     CDS             49969..50283
                     /locus_tag="VUR46_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456150.1"
                     /translation="MKLNDFLKPELLGNRFFAVKGYTEVLDRETNKPVALRLNVSIQD
                     ENSDFFMEMIQVKINTLSPTASVQEMANNKTCPVSLKDLNVGQFNGNLWFACSDVLPV
                     TK"
     gene            50317..50706
                     /locus_tag="VUR46_000683"
     CDS             50317..50706
                     /locus_tag="VUR46_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456151.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKGLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            50873..51640
                     /locus_tag="VUR46_000684"
     CDS             50873..51640
                     /locus_tag="VUR46_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET5456152.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQVAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEHEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHFEVISTDWATDKILKQLPRL"
     gene            51826..52605
                     /locus_tag="VUR46_000685"
     CDS             51826..52605
                     /locus_tag="VUR46_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HET5456153.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTDIKSKEKLQR
                     RTFDELTPEEQEQRLERMKKTRLEAKWNLLRLVDCNYDDNTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYLTVLEKQKRGAWHAHILLFSVPYVPHRQLLELW
                     EHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDRFY
                     TYEDFNYDSSVVLYETEYISKVYKDGQYFDNHVKYKKIKLD"
     gene            52622..52825
                     /locus_tag="VUR46_000686"
     CDS             52622..52825
                     /locus_tag="VUR46_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HET5456154.1"
                     /translation="MIATVTKNDLVALGFSEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIVSELLGFDVQNSTLKE"
     gene            52829..53962
                     /locus_tag="VUR46_000687"
     CDS             52829..53962
                     /locus_tag="VUR46_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5456155.1"
                     /translation="MAIRKGKDGNWIVDISNGFDPITLKQRRIVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     YNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYTSN
                     PANLIKKLPIEKTKMQFWTVKEFQHFLTLFETEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFTSNTIHITKSVYVNKGISHVSTTKTKAGTRRIIINKKLSHELQQWQQKQKHL
                     LEQFTSDSMTLQVFQGSPITITKNAVEKQYKKILERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            54003..54440
                     /locus_tag="VUR46_000688"
     CDS             54003..54440
                     /locus_tag="VUR46_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET5456156.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVDSFVATDEE
                     KAAAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            54656..54892
                     /locus_tag="VUR46_000689"
     CDS             54656..54892
                     /locus_tag="VUR46_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET5456157.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAFIEKI
                     EDMYDIKVADEAYKKWVECSKKSISHEEMMRRYG"
     gene            54885..55616
                     /locus_tag="VUR46_000690"
     CDS             54885..55616
                     /locus_tag="VUR46_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET5456158.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEKL
                     NYIFKSNANNFETDVRNEIKNNIKFNPFINWFKKRYRDERYYETETQIFVHAGIDEEA
                     EKLWKELTSSEIFTNKFLITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYFI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
BASE COUNT        17112 a        11631 c         9799 g        17170 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctatatttga agaggcgttt
       61 aaactatctg acataaaact cgttctagag gaaagacatc ctttaaaaag ttagtttatt
      121 ttacaactta gacatcaagg taggttaacc ccttcatgga aaaatcaaga ctcttagcac
      181 tatgggttaa actaccactg gagacgtaat caatcgctaa accacgaaaa cggctaatag
      241 tggtcatatc aatatttcca gaacattcaa tccgagaacg tcctgcaatt agggtaatgg
      301 cctgttcaat ctgttccaat gacatattat ccaacatgat aatatcagca cccgccgccg
      361 cagcttcttc ggcagcagca aggctttcca cttccacctc gaccattttc acaaaaggag
      421 cataggcacg cgcttgagca attgcctttt gaacactacc tactgccgca atgtgattgt
      481 cttttagcat gatagcatct gataaattaa agcgatgatt atagccaccg ccaactctca
      541 cggcatattt ctcaaaaaga cgtaaattag gagtagtttt tcgagtatca aataccttaa
      601 tgcaatcatc gcctaaggct tctacataag cagctgtcat cgaagcaatc cctgataaat
      661 gttgtaaaaa attcaaggca acgcgttcac atgttaagag acttctcacc gagcctatga
      721 tttctaaaac caaatcgcca ctagtcaaac gatccccatc cttaaattga tgaggattct
      781 ggaaggtcac ctcggcatca aatagggtaa aaaccctttg aaaaacggtt agtcccgcta
      841 aaacaccagc ttccttggca aaaagcgaca ccttggcttg gccatgatga tcaaaaatgg
      901 cattggtact gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc aatgtatcat
      961 ctatttgaaa aggggttaaa tcagttgaaa tgattgacat cactaagtcc tctattttta
     1021 atatcacttg taagcactag aggcaattac tattaacttc cataggaaat cacaagcctg
     1081 aatacctcat ttttaattct aacaagtgtc aatacaattg tcaagacaat tgtatttttt
     1141 tgtgtataat agtcaagtac caataggaaa caggtggtct tttgagcgcc aaaattgcca
     1201 acctatttcc atattctaac tgaaaggaca attcaatgat tcatttaata atgattagcg
     1261 ccattgctct agccattgga attggttacc gcaccaaaat caatattggc ctgctggcta
     1321 ttgctttttc ttacctcatc gcaaccactc tcatgggatt aagccccaaa gaacttcttc
     1381 atttttggcc aacctcactc ttttttacca tttttagcgt ctctctcttt tataacgttg
     1441 caacaactaa cggtactctt gatgttttgg ctcaacacat tctctaccgc acacgcaccc
     1501 accctaacgc cctctacatg attttatacc tgatggcaac ccttttgtct gctttaggtg
     1561 ctggattttt cactactatg gccgtttgct gtcctctagc gattaccctc tgtcaaaaag
     1621 cggacaaaca ccctttgatt ggagctcaag ccgtcaattg gggagcttca ggaggggcta
     1681 atttgataac cagtagctca ggcattgtct ttcaaggcct gtttaagcaa atgggatggg
     1741 aagagcaagc tttttcactt ggcaatcata tctttatcgt cagcattatc tacccactca
     1801 tcgtcttgct tttattatcc tgttacagtc actatagtaa gggaagaaca aactcatcct
     1861 tgactattga ccaaccacca ctcctcagca aggttcaaag acaaaccacc ttgctcatga
     1921 tcagcagcat ggttttggtt tggctttttc ccttgttgca tctcattttc ccaaacatcg
     1981 cctggatagc tacttatcga aaaacatttg atattggctt tgtctcaata ctcatggtct
     2041 gcctcgcctt aaggctcaaa ttagggaagc aagaagccat tttggctaaa gttccctggg
     2101 ctacaattat catgctctgc ggcatgagct tactaatgtc tctagcggtc aagtcaggtt
     2161 tagtcacact gatagggcac ctcatgacaa catccattcc tcatttctgg ttacctctgt
     2221 tcttttgtgt gatagccggg gtgatgtcac tctttagttc caccctatcc gttgtagctc
     2281 cagccctctt tcccatcatt gctatcatca gtgctcaaaa tcctcagatt gatattcact
     2341 tactcacaac agccaccgtt attggcgctc tatctactaa tatctcaccc ttttcatcag
     2401 ctggttctct cattcaactc tcacttccca atatagagga acgcggcctt gccttcaaaa
     2461 agcaaattat tctgggtgtc cccatcagct taagtttggg actcttgacc acctggattc
     2521 tcatccttct agcttcctta agttagattc attatctaac ttaagggtgg acttggtata
     2581 ataaagtaga cacaaaatta agtggaaacg aggaaaagtc attatgccaa gaaaaacctt
     2641 tgataaagcc ttcaaactct ctgctgtaaa cctcatcctg taaaaataat tagttcaact
     2701 ttaaaaattc atcccaatag tctttatcga tggattcaag aatatgaaaa atatgaagaa
     2761 agtgcgttcc caggacatgg gagcgcactt cgtcatactc aatttgagat gtagtgaaat
     2821 gaaataagaa caggacaaat agatcaggat agtcaaatcg atttctaaca atattttata
     2881 agtagatgtg tactattcta gtttcaatct actatagtaa agttgacttt cctgtaccat
     2941 ttttaccagt aattaatgtc acgtctgaac tcgaagtatc aaaagaaata ttatcaaaca
     3001 atatacgatg atccacccta tacgaaatat tttctacttt cattttttct ccttttgaac
     3061 taatagcaaa agaaacagtt ctgttttcat actctttccc cttcatctat attattcgta
     3121 atgaaaaata aaaaaataaa atttttttaa atgattatga ttcagaattt gtttaatata
     3181 ttaaaataat atataagcaa ataaattggg agattgaaat tcatttctag caatttgtta
     3241 gaagtcacag tctactattc taaccacagt atactatatg tgttacaaga aaagactcaa
     3301 aaacttctcg tcagtgtaag aatgtttgaa acactattta aaactaaata actataagaa
     3361 gtagatcagg tgaacaattt cagtacctac tctataagct atacgaagat atttttcaac
     3421 atgatggata aaacgatcac tcttttaaag ccatcttatt tagaaaagag aaaccattta
     3481 agcatagatg ggaccttctt gccctgtttt aaatttttct taaactagag tctgtaaaag
     3541 attggcttca ttttcacatt ttctcctagg aggaatgtcg taatgcaaaa gaattaaatt
     3601 caaataaatc atagcgatga cgactaatcg agtactcaaa cggagttccg ttatccaaat
     3661 aagccacttg ttctacttca aataccggtt ccgttggaag gagctgcaag taatattgct
     3721 cattttctga actagaagaa gctcgtaaga tttttgtagc actggcaata tgcaatccta
     3781 actttccttc aatgtaattg taaatcgatt tttgtaaaat atcttcagta atacctggaa
     3841 taacatcggt actcatataa gtttgttcca gaacataagg tttaccgtca ataatacgca
     3901 ggcggtaaat attataaact ggactctgca aagcgacctg tagtttttct gctaaaaatt
     3961 catttgcaaa ttctaatttg aagtgaataa tcctcgagtc aattgtagaa tgagcatctt
     4021 cagatatttt tgtcagtccc cggatatctc tttctggaac gattaatttt ctttttgagc
     4081 tgccacgaga gagaacaaag gttccctgcc cacgttttct aaaaattaag ccctcagaaa
     4141 ctaacaagtc taaagctttt ttgatcgtca ttcgactaca ggcaaactgt ttagctaatg
     4201 tcatttcatc aggcaattgt tcgttcatgg tatatttatt acaaagaatc ttttcacgaa
     4261 tctcattgta aataaataaa tattttgtac tcatttaatc tggttctctc tataatattc
     4321 taatagtagt ataacaaagt tcaagaaatg aggcaaacac aagatatgta tcaacaattt
     4381 ttaaaaatgt ctagacaaat tttaaaatta tgctatactt tatgtatagg ataatagaaa
     4441 ggaggttgag catgaaaaaa aagttagtat ttcctaatct gttttggtgg ggagctgctt
     4501 ctagcggacc tcagacagaa ggtcaatatg gaaaagtaca tgaaaatgtg atggactact
     4561 ggttcaaaac gcatccagaa gattttttcg ataatgtcgg acctcttgta gccagtaact
     4621 tttttcatac ttacaccgaa gatttccact tgatgaagga aattggagtt aattctttcc
     4681 gcacttccat ccaatggagt cgactcatca agaatttaga gacaggtgag cctgatccaa
     4741 aaagtattgc tttctacaat gccatcattg aagaagctaa aaagaaccag atggatcttg
     4801 tgatgaattt acatcatttt gatttaccag tggaacttct tcaaaaatac ggtggttggg
     4861 aaagcaaaca tgtagtggag ttattcgtga agtttgccaa gactgctttc acatgctttg
     4921 gagataaggt tcattactgg acaactttca atgagccaat ggtcattcca gaagcaggat
     4981 acttatatgc tttccattat ccaaatctaa aaggaaaggg aaaagaggcc gtacaagtca
     5041 tctataatct aaaccttgct agtgcaaaag tgattcaact atatcgctca ttaggacttg
     5101 atggaaagat tgggattatt ttaaacttga cacctgctta tccaagaagt aattctccag
     5161 aagacttaga agcaagtcga tttacagaag acttctttaa caaagtcttc ttgaatccag
     5221 ctattaaaag gaactttccc agaaagattg gtaaaacagc tagagagaga tggcgtgtta
     5281 tggagtcata ccgaaaaaga gcttcaactg atgaaatcaa atacggttga ttttcttgga
     5341 gtaaactact accatccaaa acgtgttcaa gcacaagcaa atcctgagga atatcagacg
     5401 ccctggatgc cagaccaata cttcaaagag tatgaatggc cggagcgtcg catgaatcca
     5461 tatcgtggtt gggaaatttt tccgaaagcc atttatgata ttgctatgat tgtgaaggaa
     5521 gaatatgata atattccatg gtttatcagt gaaaacggaa tgggtgttga aaacgaagca
     5581 cggtttatcg gtgaaaatgg agttatcgat gacgtgtatc gtattgaatt ttatgaagaa
     5641 catttaagat ggctacataa agccattgaa gagggaagtc actgttttgg ataccacgct
     5701 tggaccgcat ttgattgctg gtcttggaat aatgcatata agaatcgtta cggatttatc
     5761 tccgttgatt tagaaacgca aaagagaacc atcaagagct caggaagatg gtatcgcaaa
     5821 gtaagtgaca ataacggttt tgaagtagaa attgaggagt aaagagagga gatattcaga
     5881 tgaaaaactc aaaatttata gatcaatttg ccacctttgc tggtaaacta gggaaccaaa
     5941 ttcatttaaa aaccctaaga gatgcattcg taacagtaat gccattatat atttttgcag
     6001 gtttaatcgt tcttttgaac aacacggtat ttaagtggat tttccaaggg gatacattaa
     6061 caagattcca atattgggga ataacaattg caaacggtac tttaagtatt tcaggtatga
     6121 ttattgctgt aatggttggt tatttcttag ctaaaaacag agatttcgaa aacccgttag
     6181 cagcatcaat gctatcatta gtttctttaa ttgtgatgat gccaaataca gtttctgtag
     6241 ttcctgacgg agcaaaagat gcggtaaaca tttcaggtgt tctttcattc aacaacacag
     6301 gtacaggcgc aatgttcgcc ggggttatcg tagcgattat tgcaacagaa ttattcattg
     6361 aattatcaaa cgttaaagct ttacaaatga accttggtga aaatattcca ccagctgtta
     6421 gtagatcatt tagcgtatta cttccagtca tgaccgttat ctccttattt ggggttgttt
     6481 cagcattatt attcaatata actggaatga acttaatctc aatcattaca atctttattc
     6541 aagaaccaat tcgtcatatt ggtacaagct taatcggggt cattattatt tactctttag
     6601 gaaatatgtt atggctattt ggtattcacc aagcagttat ttacagtgcc atcctagaac
     6661 cattactatt aattaacatt actgaaaaca tcactgcagc aaataatgga caagccattc
     6721 cacacatcat caacctatca caaatacaaa cattcacttt aatgggtggt agtggatcta
     6781 cattatgttt attaatagca acattcttag tgagtcgcaa tgctgtctct aaaaacgtgg
     6841 ctaaattatc ttttggacct ggtatcttca atatcaatga accagtatta ttcggttacc
     6901 caatcgttta taacatttca ttagctattc catttatcac agttccagtc cttggtattt
     6961 taatcagcta cttagcaaca gttacaggat tcatgagtcc tgcatttata caagttcctt
     7021 ggactacacc agtattctta aatgcatggt tagcaacagc aggggacgtg agagcagttc
     7081 tagttcaatt catcatcttt gcacttggag ttcttctata cattccattt atcaaagtta
     7141 atgacaaagt tgttgaacaa gaaatggaag gttaagatta tgaaacaaat tttattagta
     7201 tgtaatgcgg gaatgtcgac aagtatgctt gttaaaaaaa tgcaacaaag tgcgactgaa
     7261 cgtgggattg aaatttctat ccaagcaaaa tcaatgacag aagctaaaaa gaatatccat
     7321 gaagcagatg tcattctaat tgggccacaa attcgttatg agttacttgc tgtgaaagaa
     7381 attgcaggaa atatccctgt agataccatt aatatgcggg attacggaat gatgaatgga
     7441 gcaaaagttc tggaacaagc acttgcatgg ataggagaaa taagatgaca gaagaaatgg
     7501 aatatatctg ttttcagctc attgccaata gtggagcagc caaatcatcc tttattgaag
     7561 ccatccaact agctaaggca ggaaatttaa aagaagcgaa aattaaagtt gaagaagcgg
     7621 aagactcctt agtagaagcg cacaagattc actctaatct catacaaaaa gaagctactg
     7681 gagaaaaaat aggattctcc ttgctattta tgcatgcaga agaccaaatg gcttcaacgg
     7741 agattattca gttgctatct aaagaattca tcgatctcta tcaaaataaa taggaacact
     7801 atcgttccca tctgtcttta ttaatgacgg ctacattata ggaacctcca aaagttggac
     7861 aaaatgattg aaaggattgg atcctgcatt acacaagatc caatcctttt cttttactct
     7921 agtttttata atatgttgaa tctagaatag tccactgtag tttctaaaaa attgctggaa
     7981 atggatgtta agctccaatt tatttgttta tatcttattt cagtttacta tactagctta
     8041 ttattctagt gaaaaattga atgagccact atttatttaa tatgtatgat gagggaatga
     8101 ctcaaaaact tcttgtcgat ataagaatat ctgagatagt attttaaaac gaaaggacta
     8161 taaaagctca tttccttcgc gcttatttta tagagatcta tcattatact ctttagaaat
     8221 caaaaagcaa cacaccttgt catcgttttc tcgttttctc gtttgctctt tgattttaat
     8281 tgggccttag taaatactac tcttaaatta aactatagtg aattgaaata agatgtgaac
     8341 aactctatca ggaaagtaaa attaatttct ataaatgttt tagcaattgt ttcgtactat
     8401 tttagattca ttttattata ctatattttt tatatagtat agtaaaatga aataagaata
     8461 gaataaatcg atcaggacag tcaaatcgaa ttctaacaat gttttagaag cagatgtgta
     8521 ctattctagt ttcaacctac tatatatttt gtttctattc tagtttttca aaaagggcaa
     8581 aaaggcctca acatcataaa aaggcatcct atcaggtatt caaaaacctt gataggatgc
     8641 cttttatcat agaaaaatta ctggttcttt ccctcaaatt gagtttttgt cttgcttcta
     8701 gactgataaa caattattta cggcgccctg gtctttcttt gtagccatag tatgcatctt
     8761 cgatgatttc ttgcatatgg tctaccattg gaagacgtgg gttagctggt gaacattggt
     8821 cttcataagc caggaaggct aattcacgag aatgttcttt ccattctttt tcgtcaattc
     8881 cttggtctct aaaattcatt tggatcccaa tacgttcacc gagttcgtag acagcttttg
     8941 cgtaagattc aaccccttct tctggagtag aagctggaag tccaagcatg cgtgcgatat
     9001 cttggtattt ttcatctgca cggtagtagt tgtacttagg ccatgttgct gtcttagctg
     9061 gacgtgtacc gttgtaacgg ataacgtacg gaagcaagat ggcatttgta cgtccgtgaa
     9121 ctgtgtggaa ttgcgcacca atcttatggg ccattgagtg agaaatacct aggaaggcat
     9181 tggcaaaggc cataccagcg attgttgaag cgttatgcat tttctcacgt gagtggaagt
     9241 ctgcattctt aactgagctt tcgagatttt caaagaccaa tttaatggct tgaagtgcta
     9301 aaccatcagt gtagtcacta gccatttgtg atacgtatgc ttctgtcgcg tgagtcaata
     9361 cgtccatacc agtatcagca gcaacaaatc ctggaactgt caataccaaa gcaggatcta
     9421 cgattgccac agttggtgtc aatgagtagt cagcgattgg gtatttacgg ttgtttgctt
     9481 tatcagagat aacggcaaat ggtgttactt cagatcctgt accagatgta gttggaatcg
     9541 cgatgaattt agtcttctta ccaagcaatg ggaacttgaa ggcacgttta cggatatcca
     9601 tgaatttttt gacaaggtca cggaagtcca cttctggttg ctcgtagaag agccacatta
     9661 ctttggcagc atccattgga gacccaccac cgagtgcgat gatggtatct ggtttgaagg
     9721 cacgcataat ctcagtacca cggtttacag ttgtgatatc tggatccggt tctacatccg
     9781 caaagatttg gtaaacaacc ttattgcgac gaaggtccag ttgttcgatg atacgatcaa
     9841 ggaaaccaag ctctaccatg gcatggtcag taacgatcat gacacgttca acgtcacgac
     9901 atttttgaag gtattgaatt gaatcacgtt caaagtatgt ttttgaagga agtttcatcc
     9961 attgcatgtt atttctccgt cttccgactt ttttgatatt caagaggtta atggcactaa
    10021 cgttatcccc aactgagttg tgtccgtaag aaccacatcc aagtgtcaat gatggcaaga
    10081 aggcattgta aacgtccccg ataccaccaa aagtagaagg tgagttacag ataacacgaa
    10141 tagctttaac agctttacca aattctttag tcaattcttc gtcagctgtg tggatagctg
    10201 ctgagtgtcc aagaccgtta aattcaacca tttgacgagc cttagtaata ccatcttcac
    10261 ggctttcaga tttcaaaact gcgataactg gtgacaattt ttcacgagtc aatggctcat
    10321 tttcgccaac ttctttacat tctgcagcaa gaatgtttgt tccttctgga actgtaaatc
    10381 ctgcttgttc tgcaatccaa gttgctggtt taccaacgat gtcagcgttc aattttgcac
    10441 cagcacagtt tttgctgttt gctttgacgc cgaagcagaa ctcttcaaga agagcttttt
    10501 cttttttgtt tacaaagtaa gtgtggtaag atttgaactc tgctacaaat tcatcgtaaa
    10561 tttctttatc aatgataact gcttgttcag atgcacagac cataccgtta tcaaatgatt
    10621 tagacatgac gatatcgtgt gctgcttgac gaatgtttgc tgatttttca acataagctg
    10681 gaacgtttcc ggcacctact ccaagagctg gtttaccaca tgaataagcc gccttaacca
    10741 tggcattacc acctgttgca aggattgtcg caacaccttc gtggttcata agggcacttg
    10801 ttgcttccat agatggttga ctaatccatt gcacacagtt ttcaggagca ccagctgcga
    10861 tagctgcatc gcggacgata cgagctgcat gagcagatga ttcttgtgct gatggatgga
    10921 aggcaaagac gattgggtta cgtgtcttca atgaaatcaa tgatttgaag attgctgttg
    10981 atgttgggtt tgttgttgga gtaataccac aaacaacacc aactggttca gcaataagag
    11041 tcaatcctgt tacatcgtct tcttcgataa cgccaactgt cttagtgtgg cgcatgttgt
    11101 ttactacgtg ttcacaggca aacaagttct tagttgcttt atcttcaaat acaccacgtc
    11161 ctgtttcttc aaaggcatgt aaagccaatt ctccgtgggc atccaaagct gctactgatg
    11221 ctttggcaac gatgtagtca acttgctctt gatccaattt acgcatttct tcaagggcaa
    11281 ctagagcttt ttgaaccaac tcatctacgt gtttttcagc aacgagtttc ttttcctctg
    11341 gtgtcacagt ttttttatca gccatatttt cctccatagc tttcaaggat cgatatcctt
    11401 tgttaatttt ttcacaagtt tattataacg cattatttca actttgtaaa cagtttcata
    11461 aacatttcac aaagaatttt taaactcttg tgaaactttt ctcattttct tttcttatca
    11521 ggttttatct ttgaagtttg tgaaatttat ttcaaatatt ttttatttca caaacttgct
    11581 tggaagaggg atttggaaag aaaaggattt gcaagtaagc gcttacttaa aacttctaac
    11641 aatacctcct ttgataagga ggctttattt ttgttgaaaa acgccttgtt taaaagtccc
    11701 ttcataaaca acttcttgtt ctgttgttag ttttcctttt ccttcagcct gaccatttac
    11761 aaaatcacct tcgtaggtcc aaccttcttt agattgaaaa gtaccttttc cattgaaggc
    11821 tccattgttg aagccacctg tatattggtc tccattttgg aaggtaatgg taccttgtcc
    11881 attcatttta ccacggacaa gactgccgtc gtaaacaatc gttccattat cgagttttag
    11941 aatacctttt ccgggaatat ttagaaaaaa gacgagtaca gcacaaaaaa caatggtaac
    12001 tactgctaaa agctctaaac gtggacgagt cagatagaca cgatactttt cataaaaact
    12061 cttaagattt tccatcttca ctctcctttt ctaaacgttc taaccaaact ttacaaccct
    12121 cctggacacg ctgataggtt tcctcaaaat ctcctgtata ccaaggatct ggaacacttt
    12181 cagatgaaaa tgagtaaatc ttatcttgac agtctactgg acacatctga cgtaagtcgg
    12241 aaacatttga agcgtccatt ccgataatat aatcaaaggc ttcaaaatct tccttactaa
    12301 tctgaagcga tgtcttgttc ttgtcataag gaatctcata ctgttgaaaa attccctgag
    12361 tccccttatg aatcggattg ccatgttccc aagaggaagt tgctcgactt tggatttcgt
    12421 agttatctgt cattgatttc ataacaaact cggccatagg gctacggcaa atatttccta
    12481 gacagacaaa gactaatttt ttcatcccat ttcctttctt ttatagaaaa acgggagttc
    12541 gtgatcccgt cttatttttc aattgcgcct tctagtgaag ctgtttcttt cagcggtaat
    12601 actgtcttga tagcagctag ttcaaaagtc aagtaaactc catctacgtc aagaactatt
    12661 gttcccttct ccgtatctac ttcatcgact gttccataaa gtccaccgat tgtaatcact
    12721 tcatagcctt tttgtagttt atttaagctt tccatacgtt tttgtgcttg tttcttttga
    12781 gagcgttgcg taaagaatat caagcccacc ataagggcta gcatgattaa aaatgtataa
    12841 tttggattca ttgtcttctc ctttgtcttt tacataggac tactatatca aatttcggct
    12901 acttttacaa gattgtacct tacttttctg gtaagaaaaa ccagagcttg cgccctgatt
    12961 tttaggatta tttcaagttt cgaacaactt ttacaagatt ttctacagta aagccatatt
    13021 ctgccaatac ttttggtgct ggggcagagg ctccgaaggt atcaatacct agaacggcac
    13081 catcgagacc aacatatttg taccagtttt gacttgcacc catttcaatt gcaacacgac
    13141 ggcggactgc atttggaaga atttcttcct tgtaagctgc atcttgttta tcaaagacat
    13201 ctgtagatgg aatgctgact acgcggattt tttcgccttg actagccaat tctttagcag
    13261 ctgagacagc aagattaacc tctgaacctg tcgcaatcaa gatggtatca aagtcggctg
    13321 cattttcata tacaacataa gcacctttag caaccttgtc gaagtctgtt ccatcttcaa
    13381 cagtcaagtt ttgacgtgtc aagacaaggg cagttggtgt tttctcactt gtcactgcaa
    13441 ggtaccaagc tgcttgagtt tcacgcgcat ctgctggacg gaaaacattt agatttggca
    13501 tagcacgaag acctgctaaa tgctcaactg gttcgtgagt cggaccatct tccccaactg
    13561 cgattgaatc atgggtaaag acataagtca caggaagtcc ttgtaaggct gacaagcgga
    13621 cagctgcctt cacatagtca gagaagacga agaaagttcc accgtataca cgaagtccac
    13681 catgaagggc catcccgttc aagattgttc ccattgcaaa ttcacgaaca ccaaactgaa
    13741 tgttacgatt caagcgattg gcatcgtctt gaagtccatc cgtcttgata taagtcatgt
    13801 ttgagtgagc aaggtcagct gatccaccta ggaaggttgg taatttagct gccacaacat
    13861 tcaaggcatc ttgacttgaa ttacgagttg cttgagaaaa accattttct aaagctggga
    13921 agtctgctgg agtcacttcg actggatcac gtccgtcgat gatggcttct acttctgcag
    13981 ccagttccgg atgagcttct ttataatctg caactaattt agtccaagct tgataagctg
    14041 atgcgccacg gtctgcaaca tgttctttga aatcagcata tacttgttct ggaatttcaa
    14101 atggttcgta gtcccaaccg agggcttgac gagttgatgc agtttcatct gctccaagag
    14161 gggcgccgtg tacagcatta gttccttgtt tgtttggaga accgtatcca ataaccgtct
    14221 tcacttcaat caaagatggc ttgcctgaag cttttgctgt ttcgatagca gcatggattg
    14281 cttccaagtc tgttccattt tcaaccaagg cagtatgcca accgtaggca ttgtaacggt
    14341 cacgaacact ttctgtaaag gaatcctttg tctcaccatc caagttgata tcatttgaat
    14401 cataaagaac aaccaactta tcaagttttt gcaagcctgc gtatgaagct gcctcgcttg
    14461 agacaccttc catcaagtct ccgtctccac agataacgta agtatagtgg tcaaagatat
    14521 tgtagccttc acggttatat ttagctgcca agaaacgttc tgcttggaca aaaccagtag
    14581 cagttgaaat cccttgccct agaggacctg tcgtagcatc aatccctgcc gtatgaccaa
    14641 attctgggtg acctggtgtt tttgaacccc attgacggaa gctcttaatc tcatccatgc
    14701 tgacatcttc aaaaccagaa aggtgaagaa gagcataaag gagcattgaa ccatgaccag
    14761 ctgaaagaat aaaacggtca cggttaatcc agtttggttg agctggattg atacgaagtt
    14821 gttttgtaaa gaggctgtaa gccatcggag ccgctcccat aaccacacct gggtgacctg
    14881 agttggcttt gttgatagcg tcaataccta ggaaacgaat tgcattaaca gatagatttg
    14941 acatagaatt tcctttctat ttgaggtgat tattgaatca cacattctat tttactatta
    15001 tatgaaaatt atccgtatgt tgcaacatac ggataacctc caaagaatat ttttatatta
    15061 taacaaagct ttaaattgaa tgttagagtc ttgttcaaaa caatcatcaa aaccacgtgg
    15121 atgatggtat tctactaagt gttgatcttg aggataagtg tacttaccgc caacttccca
    15181 gataaatgga tggaaatcgt attgcaagcg atcttttcgc attttccaaa gttctagaat
    15241 ctcattagta gaagccatga agttagacca aatatcatag tgaactggga taatgacttt
    15301 ggtacgcaga ttttctgcca tacgaagaag gtcgatagat gtcactttgt cttggatacc
    15361 taccggattt tcaccatagt tattcaaagc aacatcaatt ttaaagtctt taccatgttt
    15421 tgcaaaatag tttgagaagt gagaatctgc accgtgatag atggttccac ctggtgtttc
    15481 aaagatatag ttaacagcct tttgagccat ttcctcatct gtaacagcta agccagcaag
    15541 ttcaccgcct gtctcatcag caccgttcac tgggagagtt accaagcaag tacggtcaaa
    15601 tgattctact gcatgaatct tcatatcttt taattcgata gtgtcacctg gtttaacaac
    15661 gatgatacgt tcttttggaa caccccatcc ttcccagatt cgtccacagt ggtaaggacc
    15721 gataaactta acatgctcta acttaggatt gttgagaatt gctgcagctg tgtatgggtc
    15781 gatatgatca ctgtggaagt gtgaaactaa gtaatagtct agttcgttga tagcaaatgg
    15841 atcgataacc attggctgaa cacgcaagtt tggttgcagc ttacgaacac ctgccatatt
    15901 tgccatttgg tgcccacgaa ccatatcttt cacttttttg gttgattttc cacggtttga
    15961 ccaaaggtcc atgacaacgt tagcaccagc tggtgtctta atccaagtac cacagttgcc
    16021 tagccaccac atggcaaagt tgccttcagg tacgacttct tcttcgattt cttcgttcaa
    16081 ccatgttccc cactctggga aagtggctaa aatccatgac tctcttgtaa tttctttgac
    16141 gtttggcata tgttgcctcc tttggatata attgttatct ttgagattag tataccaccc
    16201 ttcaaaacac taaaaaagac caagaaaaac acaggtttgt gttcatcatt ggactgtcct
    16261 tcaaatatct tccaaaaaag attaaactac tatttcttga tttataagtg tttgaacctc
    16321 ttcttggaac ttactagcca acttgctgtc tacaatataa gacgaaataa gactagaaag
    16381 attttcactg aaacttttgc tcttattacg aaatatattg tgtttaagat agtctagcat
    16441 tttcaaaata tcttctgctt caaggatagg attaaccctt aaaatcggaa atctgctatc
    16501 caaatcatca ttagtagtaa tcactacatc aacttgtgca atatcttcca cactcttaaa
    16561 ttgttctgtt gtaaatacag tgtcaatttg ctcatttgga aaataaagtt tgcattgttt
    16621 cagcaaaagt ctcgaaaccg caacaccttc atcacaaacg agataaactt ttttcatatt
    16681 tttttgagac gatggtgtat actttaaaaa tcctccaata tgaatcgtca aataggcaat
    16741 atcatcgtct gttagccgaa taaaccatgc tccttctaaa atttccgcag attttctagt
    16801 gactaaaaat aattctccat acttggatcg aatttgtttt gttagaggat ttttagaaaa
    16861 aataccgtaa gtctttctaa ataacaaggc tttacagtgg atcatcaaat ttcgtaacaa
    16921 atcatccttg ttctcaatct ccattcggat ttgtgattca aaataccaga taaattcttc
    16981 taaagcaagt tttaattgcc gaaaatcatc actttctgca tgaatatcca aatctttacg
    17041 ataggagagg aggagaacag ctacaagaga aacttcaagt cctgacaaag aaatttcaaa
    17101 cttttgaaac aaccgttctc ctaatttctt agacacctga tactctattc tttttcttat
    17161 caaagaaaat tctttctcta tatcctgatg tctttcttga tactgttcaa cattatgaca
    17221 gcttaacagc aaataaggta gaacctgcaa cataaaagtt atttcatgat gatttatttt
    17281 cttccctaaa tcttgttcaa ctaaaggaac ctgttcctta aaaaattggt tcatttcaac
    17341 agaaagcaaa cactcatcat ctaacctctc tttcatctta tcttctaaaa tagatacaaa
    17401 agtggcattt tcttccataa aaatatgata tagaagcgat tgaagatact gaattttatt
    17461 aagagggtgg gcatgaaggt ggtatccctg tgacttgctc acttgcaaga tcacctgata
    17521 ttgttccaaa gttagttgat aacgaatact attcaaatca ttgagaacag tattcctaga
    17581 tacctctgtt aactctatca atttttcaat cgtaatacgt tctttagaaa tacctatcca
    17641 tagtaacatt atcatcatac gttcatgcgc actcatgata taatcgtacg aatctacttc
    17701 cgataatagt ttacaacaag catctctctg ctcttccgtt aagtgaatac caattcgtgg
    17761 aatactaatg atgtgaagcg cctcgtcacc cagagcagca ttgattttgt caatgtgata
    17821 ataaattttc cttcttgact ctttcaaatc tttcgaaatc gccataatcg ttttggacgt
    17881 ttcttgatcc atcaaatatt gaagcaaatc acaacttgcc ttatccagta ccatattaaa
    17941 aaatccccca aatctattga tatcacagca attcttttta ttttaccata tatatatcaa
    18001 gcgctatttc taaaaaatct tttaaaatta cttcaactcc aactttactc tcaataaaaa
    18061 tcaaatgtaa aaagaggagc taaatttatc tttttctcct ccttcatcgt tcttactttt
    18121 gaccataata agcatttggt ccatgtttac gttggtagtg tttttctagt atgtactggg
    18181 gagcaggtcc aactcttgga ttgatttgtt ctgtaaagcg attcatcttt gatacttcct
    18241 ctagtacgac agagtgataa acagcattct ctggattttt gccccaggtg aatggaccgt
    18301 gattgcgtac aacaattcct ggtacttcaa ccgggttaag tccgcgatgt tcaaactctt
    18361 ctacgataac caggccagta tctttttcat aggccacttc tacttcgtcc ttggtcaaac
    18421 tacgggcgca agggattgaa ccgtagaaat aatctgcatg ggttgttccg tagaaaggaa
    18481 tatcacgacc tgcctgagcc caaccaacag cttctgtcga atgggtgtga accacactac
    18541 caatttctga ccaagcctta tataattgca catgagttgg gaggtcggaa gatggtctta
    18601 aatccccttc taggatctta ccatctagat cagtcactac catgttttca ggtgtcaatt
    18661 cgtcataatc cacgcctgat ggtttgataa caatgacacc gagttcgcga ttgacttcag
    18721 atacattccc ccaggtaaat ttgacaagtc catgttttgg caatgattga ttggcatcac
    18781 agactcgttt acgcatagca ttgattactt gattcatctt acatcaaacc tgctttctta
    18841 atgagtggat agagaaaagc ttgcgcctct tgaatggctg cgcgtgtttc ttctactgtt
    18901 tcacaatttt cagaccacat ttcgattagg aaaggtccat tataattggt ttcctttaaa
    18961 atatcgaaag cttcttccca tttgacacaa ccttgcccga aaggtacatc tcggaactgg
    19021 ccctttgaac tttctgtcac tgcataagta tccttgagat ggagagctgc gatggcatga
    19081 tgaccaagat aaaactcact atagatatca ttatgccatg cagacacatt accaatatct
    19141 ggatatacaa agaggaaggg agagtcaatc tctttttcta tagccaaata tttttcgatg
    19201 ctattgatga aaggatcatc cataatttca atagcaagta ccacctgagc ttcttcagcc
    19261 cagtcacagg cttttctcaa atttttgata aaacgttggc gtgtctgggg tgccttttcc
    19321 tcatagtaaa catcgtaacc agctaattga atcgtacgaa ctcccaagtc ttgagctaat
    19381 tcgatacatt ttttcataag ttctagagat ttttcctcta gaactggatc ttttgatccc
    19441 aatgggtagc gacgatggcc tgaaaaacag atagaaggaa tacgaacacc agtttcatag
    19501 attgctttga caacttccaa gcgttcttcc ttactccagt caagtcttgc taaacgctcg
    19561 tcacgttcgt caatagacat ctcgacaaaa tcaaagccta actccttggc aaaatttaaa
    19621 cgttctagcc aagtaaagtg tgttgggatt gccttttcat aaattccaat tggacgtacc
    19681 atgatttacc cccaaattcg tttgatttca tccttgaagg cacgcgctgc tcctgctgga
    19741 tccacagcct ctgtaattcc acgacctgcg ataaaggtaa agacatcaac accttcaaag
    19801 agtttgagag tatctacatc tagaccacct gttacagata cacggaagcc catgtcaatg
    19861 agttttttaa tcttattaag gtctttttca ccccaagttt caccagcaag aagagcatca
    19921 cgagattggt gataaatagc ttgtgagata cctgcatcta gccaaagctg agcttgttca
    19981 aaagtccaat cgccataaag ctcgatctgg atttcgcctc gttctcctcg ttcagtcttg
    20041 atagccttta gagctgcttc catagtaggg atggttgcac aacagataca agtcatccag
    20101 tctgctccac gaaccgcatt atttttagca actgttccac cagcatcagc acattttgtg
    20161 tctgccacaa taatcttatc tgggaaaagg ctacgcaaga cttcagccag ttcacttcca
    20221 acttgaagca agcaaacagt tccagcttcg ataatatcta cttcctgacc aacagaaaca
    20281 gctgctttaa tcgctccttg caagtctgaa tagtctaatg caacttgtaa attaggtatt
    20341 ctttttgtca tttctttatt cctctttcta actttccaaa tccaatcctt cgagataagg
    20401 gctatcctta gattcttcaa tcatagccaa gacatcttct ttagtctggc aagcctgtaa
    20461 acgtgcaata gaatcttcta attcaaacag ggcaataatt tgtggaatgg ctacacttgt
    20521 gtgaattttt gagcttgttg ctgctagtgc caacaaaaca gatacctctt tcccatctga
    20581 aaatacaaca ggattttgta aggtaatcaa tgaaaaggca tcactttgca caccagcttc
    20641 aggtctagcg tggggcatag ccatacctgg catcaagata tagtaaggcc catactcttc
    20701 agtcgattca atgatagcat cgtaatactc tggcaaaatt gccccacttt caattaaggg
    20761 atctactgct accttgactg cttctttcca attgttagcc tctaaaccta gtcggatcga
    20821 gtcattgtca attaaagctt gttttaaatt catatctgcc tcctttattt aagagggaga
    20881 aggacagaaa cgataactct cagtttctgt ccagccccct ccaacctttt actgtagtgc
    20941 ttgactgagt ttttcggtga tttctttatc atccatcaag ttatcaagcc caattaactt
    21001 cccattagtt cgcccttcca attcttgaat caaatgaaga gaagcgatta cgatgtcata
    21061 tcctactgct aaacctttag cttcaccgac actgcatgaa ttgactgtaa aatctgtttg
    21121 attaagctta cggagagcat tttcaacctt catcttgata accattgatg aacccattcc
    21181 atttccgcac gctgctaata ctttaaccat tttatttctc cttttctaga tactaagctt
    21241 cttcttgaac ttcaccgttg taatatttct ctttatcttt tgctttggca aattgaagtt
    21301 gaggaataac aagcaagaag agacacacaa gtacataacc aacaatacca aggtatttga
    21361 agatatatcc aaatccaagc catgggaatt caaagtcgat atttccatgg tagccaccat
    21421 aagatgccaa atcgagaagg gccacacaaa gagctcctag agcaacttga aggacacctg
    21481 atataaagga aaggataaca gccgctttcc atccgccgcg tttatcagcg tagactgcaa
    21541 tggctgcatt gtcaaagaac actggtacaa atcctgtaat aataagaatc ggatttttaa
    21601 agacgatgag caaaacaatt gtaatcaatt gaccaatcaa accaaaggta aatcctgaca
    21661 agacagcatt tggagaacca aatccataag aagctgcaac gtcaaccgct gggaatgaac
    21721 ctggcaacaa tttgtttgaa ataccttgga aggcgtttgt caactcagat acgaacattc
    21781 ggacaccttg catcaaaacg aacaagtaaa ctgagaaggt aaaggctgtt tggataatgt
    21841 acataaagaa atcttgttta gcaggattga atagagttcc tgaagtgatg acttctttat
    21901 tagacataat gtctggaccc aagattaaaa gaatggctcc gaagaatacg agcatcaagg
    21961 tagcagatgc aacaactgta tcgtggaaga ttgagaggaa cttaggtaat ttaagattgt
    22021 ctaaactttc ttctttctta ccaaagcgtc ctgctacttt atctacaaac cagattgcaa
    22081 attgctgttg gtgaccaatc gcaaatccgc caccaccagt caagcgttga gttgcctcaa
    22141 cagtcatatt tgaactaact gcccagtaaa gtccacagat gataccaatc gctgctgtac
    22201 cgtaagcatt gcgcaattgt ggtactaaga atagaaccat aagagatact gttgcagctt
    22261 gttgtaccat gatgtgacca gtaataaaga gggttcttac cttcgtaatc tttcgaagag
    22321 ctacgagcaa gatatttatt ccaaaaccaa tcaatagagc tgtagttgca gttccaacaa
    22381 aatctggaaa ctctgctgca attttgttgt ttgctgcagc aagtccaaag taagggtcga
    22441 taaccgctgc accaatttgg aatttgtagt taagagctgc taagattgga cgaaaggttg
    22501 taaccaaacc accagcaccc acgttaagca acatataccc tactgttgat ttaacaaacc
    22561 ctgaaaaaac gtcatgggca ggttttttca aaagtgcata tcctatcaac accaataaac
    22621 ctacgaaaaa tgcgggattc tgcaaaatat tgctagaaaa ccaatttaga acacttgaaa
    22681 cgacttccat aattgttctc cttttgaatt gtttttgtaa gtttattata taatgcgaaa
    22741 gcgcaaacaa aaagaccaag aattacacag cggactgttc actcttggac tgtatgattt
    22801 atgatgtttt acaaattatc ttattttctc gtagctagat aatagggaag aattttagaa
    22861 taagacttca ataagccttc tacgatttct tcttcagacg aattttctgt cataggaaca
    22921 tctaccttca ctaaaacttt tcgaacttct tgactcctca ccttctcgcg taaagtacga
    22981 cgcttttctt cattcgcctc ccaccgttga ctttgaccat tagagtaggt tagataataa
    23041 atccctttaa cggttggaat gtctaaaact ttggtctgct tgcccagtgt ttgctcatcc
    23101 ttcttacgtt cgatgaaact gacttccaaa gaaattccaa agtcagtaga tgtcccatac
    23161 aaacgtaagg ccatcatagg ttctgtcact tgtccgtctc tctgtagata aacccaaaaa
    23221 tgtggtctca aacgctgggc ctgattcatc cactgactag tctgttggag ttgccattct
    23281 ggatggcttg cttgaaaggc tttggccagt tctgtaaaag cctttcgggc ctcttgtcct
    23341 ttgtggcgga acgccagcat cttctctcgc tctgctcccg ctttatcagg actacggtac
    23401 tgcaaaccag aaaagtctag atagtctctt atcttattca acatcagttt aacctcctct
    23461 aactagcaaa aaatcaggtc aaccctgatt ttacttattc tgtatctaca acaacatagc
    23521 gatttggctc atcaccttca gagtaactag tcacgccatc catacgtgaa ataatacgat
    23581 ggataatctt gcgttcgcta tttgacattg gatctgtttt atgactgcga ccttcttcca
    23641 aaacacgatt cgccaatttt tgcgcatagg tctgcaagac ttctgcacgg tgttcgacat
    23701 aatcattgac attgattgta acgtagaagg ttttggaata gcggttgtaa agataatttt
    23761 gagccaacag ttgcaaggcc ttcaagactt taccatggta gccgataata cgacctggtt
    23821 cgttggtgtc aatttgtaga ttgatgctac gacggttata atcatttgaa agtgtagctt
    23881 caacatccat gtcatccaca atcgcttgaa cataggcagt cacatccgta gccacctggg
    23941 caatatcata actttgctcg accttcaagc ccatctcttt caagtcttga ttttcagttt
    24001 gatcttgctc agtttcaagg tcatcagcgc ctgcttcttc cctcatcgct tcctcgattt
    24061 gaagttcatt taaaatctca atgtgaccag tttcttctaa gatagtgctg gcatgtcttt
    24121 catgttttaa gatttcagcc ttgacttcat cagaaatacc ttgaccttct tcctctattt
    24181 ttttaatagc attaaccaca tgaccaaggt caacggtttc ttcactaacc gtcttcacag
    24241 gctcgttcaa atcattgatt tttttcggaa cgccttttac tacctgttga tttgctttga
    24301 caacagtcgt ttcactaatc gcttcaatat ccacttgggc tggtttttta ccaaatagac
    24361 caagaaagcc ttttttctcc ctagaaatga ctttgatatg agccttcatt cttggaatat
    24421 ctaattcttt caatcctttc tggattgctt cttcaacagt tgaacctgta aatactacca
    24481 ttaccagatt cctccttatt tatttcgttt tctgagcctt tttcttggct tttctttttc
    24541 tattttccaa atctttttgt gtctgtacta cggcctcgcg ctctgcgata atcttgaatg
    24601 gattattcaa gaaataggtt tgcaagactt gataagcatt agacactgtc cagtataggg
    24661 cgactccacc tggcgcataa actgcaaaga taaaaatcaa gactggaatc ccatacatca
    24721 tcgcagtcgt agcgccattt cgctcagaca aagctttgtt ggacaaccaa gtacttaaaa
    24781 aggtgaatac tgctgctaaa atcggaagaa caagggttgt atccacacta ccaaggttaa
    24841 tccataagaa atgacctgtc tttaaaaagt caactcttga tagggcttgg aacagggcca
    24901 aaataaccgg catctgaatc aaaatcggcc aaagagagtc tgactgtctg acacccattt
    24961 ctttaaatac tttacgcatt tcctgctcta gtttggttct gctttccata tctcgacctg
    25021 gatattgttc tcgaagcgcc ttaatgcgtg gctgagcttc ctgcattttc ctagaagcca
    25081 ccatttgcac ctgaaagact ggcaagagga ctgtacgaat caagaccgta aagagaataa
    25141 tccccactcc gatactaata tcaaacgata aaaagcgaat gatttccgca aagaagtaaa
    25201 ccaatttact ccaaaaatca gccgattcgg ctgtaatatc gctagttacc ccattagtcg
    25261 cacaggctgt catgattaac agagacagtc ctagcaaact agtcaacttt agtttctttt
    25321 tcactcccat ttccttcccg gtaaatcttt gataatttta atacatggag tagatttttc
    25381 tccatctctg cgtatcccaa ggtttcgact ccttttcgag caatgacaac aaagtcgaca
    25441 tcttctacca gacccccttt tgcattctgg ataatatgcc gaatccgtcg cttaatttga
    25501 tttctagtga cggcattccc cagttttttg ctaactgata gacctactcg aaaatggttt
    25561 ttctggtttt ctaattggta gaccacaaat ttgcgattag caaaacttgt cccctccttg
    25621 aaaatcgcct taaaatcttt ctctcttttt acacgaaagt ttttcttcaa aactcaactc
    25681 catctattaa attactacta ttataccata tttttcaaaa aagccaatca tagcaaggtt
    25741 ttggacaatt tcatcagaaa aagaagctgg aaaaataact ttcccaactc cttgtattga
    25801 atattttttt agtttcactt attttttcaa gcgttcaacg tcacgggcaa tgactaattc
    25861 ttcatctgtt ggaataacca agacacggat tttagctacc tctgttgaga tgtctcctgt
    25921 aacgccaaag acattctttt catcatcaac atcacaacca aaccacgaaa tccctgagat
    25981 tacatcacga cggaaattct ctgcattttc accgacacct gctgtgaaaa caatggcatc
    26041 tgctccattt agcactgcaa ggtactgacc gatatgtttt tggatacggt caacatacat
    26101 ttcataagcc aagctagcct cgtgattccc ttctgctaca gctgcttcta tatcgcgcat
    26161 atcgctagaa ttagcagaaa ctcccaaaag acctgattca cggttaagaa cacgactgat
    26221 atcttctggt gtgttaaaat cctctgtata ttgcattaaa taaggaatga tagctggatc
    26281 aatatcccct gtacgcgttc ccatcataat accaccaaga ggagtgaacc ccatagaagt
    26341 gtctacagat ttgccggctt tcacagctgt aattgagcct ccgttaccaa tatgacaggt
    26401 aattaacttc aagtcttcta atggacgtcc caagagtttt gcagcttctc ctgctacaaa
    26461 ctggtgactt gtaccatgag caccgtattt acgaaccttg ttttctgtgt aatattttgt
    26521 tggtagaggg tagcgataag ctttctttgg catacttgtg tggaaggaag tatcaaaaac
    26581 aactacactg gtaatgtctg gcaacaattc cttgaaggca cgaacacctg ctgcattggc
    26641 cgggttgtgt agaggagcca acaaactcaa ctcttcaact ttttctaaaa catctccctc
    26701 aacaactgtt gattctttga aatattctcc accagcaaca acacgatgtc caacacctgt
    26761 aatctcgtca taagccttga taatatcgaa acgaatcaag tcatccaata aaattttaac
    26821 ggcttgtgta tgattttcaa tatccaaaat ttgttgttca gaacggccgt caaattttac
    26881 agttgaaatt gaatctttca aaccgatacg ttcaatcaaa cctttcgcca atactttttc
    26941 ttctggcatt aagtataatt gccatttcaa acttgaactt cctgcattga ttgcaattgt
    27001 ttttgtcata acatgatacc cctttttaag cgttttcaac tattataaca aaatctattt
    27061 tatatttcag taccttgagt ccatttttga aaattttctt taaatttcat taaaacactt
    27121 gcatcttgca agctagcaag tggataaaca aaaggctcca ctgctatttc acttttcttc
    27181 tgtaggataa aaatagtctt agattgttta gcattagcaa agagattttc aggtaaacta
    27241 atcatagcaa ccagacttgc ctcctctttc aaccagactt tcaacaaatc actttgagga
    27301 ctggtcaaca aatcactcgg agctagaaaa atagcatatc catctgactt aaggtactta
    27361 aacccttgtt ccatgagcaa gtgatgagcg taagtatgtt cttggctaga agcaacttga
    27421 tggcgcgacg caacggcatc atcaggataa tagccaacag gcaagtcact gatgaccaca
    27481 tcgctttctt tgagcatttg tgggcgaacg gcatctcctt ggacaaagcc agcctgcaaa
    27541 ccaattacat ctgccatgct agctgccaga tcaatcagca aatcatccac ttccattccc
    27601 aagtaatcca cctttttatc aagcgaggtc aagaaagtag cgcctagaat tcccatccca
    27661 gaacccattt cgaggatagt aatttcctcc tctgtaaaca actcttccac aataaatacc
    27721 aaaagtaagg caatagcatc tggcgtaaac tggtgattgg cctgcaaggg ttctgtttgc
    27781 ccagccttca tcaagagaaa ctggtaggtc ttgagccatt cttctttgcg tagtgctaaa
    27841 cgcttaaggg cctgattgtt gtctttgacc tggtttagct cagtttcacc atccagatag
    27901 atgctatttt gctccaccaa ggcgtcataa aagttggtcg ccaaatcact ttggatgact
    27961 tggacattct ctagtaaata gatataagct tgttcaattt tttcaaaatc catattccta
    28021 tcttatcaaa tttcccttct tttttccatc cttatagaaa aatcactccc tgactaggcg
    28081 agtgattttt gggatactgt taaaaagaat tctgagtgat tcccttgaaa caggtcttca
    28141 gcgctataga gaatctgact atgcacagat gaaaaaccat gctcaattag cttgttttcc
    28201 agttcagcta aatcaaatcc atgatgatta gcttctgtct tggtaaaatc agcaatgatg
    28261 agtttcccat cttccttcaa atgttgatga aacagtgaga gatccgcatc caaatcaggc
    28321 atatgatgaa gaacccgact aacagcaagg caatcaaact ctttctccaa gggatttttc
    28381 ggtaaatctt gctccaaaaa ctggatattc ttgattgctt gctgctccgc tttcaaacga
    28441 gcttactcca acattttctc agaaatgtct acaagagtaa ctgacttagc ctgcttggct
    28501 aggggcaagg ctaatagacc cgtgccacca ccgaaatcta aaattacttt gtctgataaa
    28561 atatcaatct gtttctcgac tgcttgacat accaagtttg cgaggaagat atttttaggg
    28621 gagtcgaaag tttctgcttt gtggttaaaa tcatgtttca tatctttagt ttagcacaaa
    28681 gtatagtaaa ctgaaataag atataaacaa atgaattgga gcttaacatc catttccagc
    28741 aattttctag aaactacagt ggactattct ggattcaacg cattatagtt gaattgacta
    28801 ggaattctct ttcttttcag gcttctcttc tgattttttc ttctccactt tttcgcttga
    28861 atcggtcgct acctcttcct ttttatctct tttctcttct ttgattttga ctgaaggaaa
    28921 cagaaactca tattggctct tagacgtacg aacagtcgtc accaagcttg ttttcttgtt
    28981 ttgatagctt acctgaccta gattaaagac ctgttcccca ctttcttgct cggctttatc
    29041 cttggttcgt ttagccatgg caaaagcaac caatttttct ttatttaaag catagtcttg
    29101 atagtgggcg atttgtcggt tcaaataaaa ttgcaacaaa agactaaaga tggctgctat
    29161 ggtgactgcg tagaggagaa cacctgcctt aactttcttc tttttccaca cgatagatga
    29221 actccctttc taagcctttt tgaaactgga aacgaaaatg aaccagttga ttgtcctctg
    29281 taatctgagc tgatttgagg ccataaacca taggctgata cccccgtcca ctagcatcgg
    29341 ttttacgaaa atcgtctgac tttgacttac cgatggcgat gtccttgcca tcttgcttca
    29401 tgtataggcg attgctttct actttttcga actgcgaacg gtctaattct gcctcaagtt
    29461 ggtccacaaa caagagccac tccttttgct cgctttgttg ctggtagcga acttctgaaa
    29521 tgaggagctg actcatagct tgaaaaagga gtaatccccc actgatgaca atgagggcaa
    29581 gcagggattc taacaaggta aaagccttga ccttatggct ctttgattgc caacaactgt
    29641 tctgaaccat ggtagacctc caatcccttt tcactagaaa atacctgaat ctcaactccg
    29701 ttgatgctta cctgattttg ccccgtctgc aaggccatct tagctaccct caagacttct
    29761 tccttttgca agatttttgc ttcctcttgc ctattttttt gaatttgtcc caaaaggagg
    29821 gtcgcaatgc tggcaaagat agctagagcg actactgctt ccagtaaaat cactgcccta
    29881 attttttgtt tccttaatgc gtttaatttt tccatttcct agatataatt gatagcgaat
    29941 cgctccttta ctggtctgaa attcaacctt agccagggac gaattgcccc cagctcggtc
    30001 aaatgtaata ctttggcctg atggtgcctg aattccttta ggaactgtca acttttgacc
    30061 gccattgcta atcatctgcc catccaagtt cagactagtc ttttgttgac tagctacact
    30121 gcgtttttgg gtttcccgat agagttcttc aaactccata aagaaaatct gttcctctac
    30181 cgctgcaaaa gtggactgga cagagccgga caagcccaag gcaaggatac tcacaagtcc
    30241 caaaactaag agactttcca gcatggtaaa ggccttaatc atagacttta cgatttgctc
    30301 ctacattttt atcattgtat tctttataag ctttagcctg ttcttccgtg atgcgtccat
    30361 cttcttttaa cttgcttagg ctagcatctt cattcttttc caagctataa agttctgcct
    30421 ggctttccac caccttaaca acagctgctt ttcctttgtc attgactgct tctttttgct
    30481 tggtcagatt aggtacaaag agcaagaaaa gcacgctgat aatcagcaag accaccaaca
    30541 tttccaccaa tgtaaaagct ttaaccttag cttttttcaa gaatgtcatc atttttttca
    30601 ttttaaaaat ttacctccat attttgatac atgggcatga gcattgccgc ataaagtaaa
    30661 acgataatca gtgccacaaa gataaaaacc agtggctgca ccaaattcat ggtgcggttg
    30721 actcgggtaa aaaaggcttc ccaagttttt tcagcataga tttccaactc actacccagc
    30781 ttggacttaa cttccccata ctctatgata agactcaatt ccttcctaaa gaaaggatag
    30841 gttcctatcg tctgagaaaa ttcacggcca tttttcaggg tttgagccag atcttgaccg
    30901 atttctttaa agagctggga accttgttcc tgcatcattt gaaaaatctg cgtcagctcc
    30961 attccctgtg aaatcatatt cccccattca cgtgcataat aggctgtcaa gtaggtctgc
    31021 acaaagattc caataaaggg aaggcgtgct aagatagaaa agacactcat cttagaactt
    31081 cttttataaa aagttagtgc taaaagggca agcacggaaa caagccctac catgcctaga
    31141 aaaatttggg gcagattacc gataatttgg gtggcaatat tgctactatc cagttgtggg
    31201 agcaggtaat tccgtagccc cagcataatt aagagaagaa aacccagcaa aatcaaagga
    31261 taggtcgcta cttcaattaa ctttttcttg accttggcca gattgtctag atattcttct
    31321 atctttccca aactcaggtg gagattgcca tgaacttcag ctagggataa ctgagtgaca
    31381 atagcacttg aacatcccaa actttccatc atttctgaga atgattcccc ctgagacaag
    31441 cccacacgca tctgggtcac acactgcttg tccaacaaag cactcctatc taaaaaggag
    31501 atggtctcca ccagatgaaa accgctagaa aagagattgt taaatagggt gatgatattt
    31561 ttttgcttag ctgtagctaa ttttttccgt ctcagcctga agacttgtga tatgtccatc
    31621 tttaagaagc tggtcaattt gctcattcca cttgactgct tggtgttctt gataatctct
    31681 gtttgcaaag tcaacgattc ctcctccccc gattaatctc tggtagcaga ctccttgcaa
    31741 aacaactgcc aattcttctt cactcacacc caactccagc agacgctcat aaacacctcg
    31801 gatactcttg gcatgaatgg ttgaaaagac tgtcgcacct gtcaaactag ctctgaccac
    31861 tgcacgcgcc gtctcgctgt cacgaatttc tccgataatc aagagatctg gtcgatgacg
    31921 caaggaaagt ttgattagat tttcataggt taggccgatt gcttcgttca actgcaactg
    31981 aagcatgtcg tcctgcttga tttcgacagg atcttcgatg gacataactt gctgcccttt
    32041 aaagagtgac ttggacaatt catgcatcaa ggtcgtctta ccactcccaa ccggaccagc
    32101 aaaaagatag agtccccgtt gcctgtactg cttgcctaat tcttcaatat cctgaaacca
    32161 aaaatgcagg tcctgctcct catcgtgcaa caaacggata accaaactct catgcccccg
    32221 ataatcgcct acagtagata aacgtagaga cgctatcttc tggtcatagg cataatcaca
    32281 ggaacccagt tgactacgtc ttttttctcc cacattcata cccgccacaa acttaaagtg
    32341 actgataacg gctgcaaact tttcaaaatc atagctacca attttacagc gctcgtctcc
    32401 taccctcata tgaagctcat aggcgtctaa cttagggaca aaatagatat cctgcgtccc
    32461 ttttttccga gctgaacgaa tgatttcttg tgcaatttct tgaaccatac ttacctcctc
    32521 acctatacta ttcgcaaaga gttagaaaaa taaaaaaagc aactccaaaa aagttacttt
    32581 tctctatttt aatttcatac ggcaagaacg attcctttcc tgactagttt gtttttcata
    32641 gcctgagcgt agtttttcgt ctgggataac ctgctcatcc tgcaaaagag ccaaagaatg
    32701 gtattgttgt aaatactcat cacattcatc acaccagcgt tggtcttccg ggtcccaaaa
    32761 aatggtcatc aagtcgcttc tacttttata aagaggggat tcttgttcca atctaaacca
    32821 gcaagttttg tagtatttga gagcatcata atactggtca aattttctac ttgctacaat
    32881 atcttcttcc caaccttcta agaaccacca cggttcaaaa tctccgtaca tttctataac
    32941 acgatacata ttcattcatt cctttgtacc gtatattata accaattccg ccagacaagg
    33001 aaagaaatat gctcatttct taattttttg ataaaaaatc cagccatctg atggatgact
    33061 gaatttctat ttacttatgt acaaaaatat ttttactact tagacttctg agatatcgtt
    33121 ttcgataatg accttaatgg catggtggtc tgctgcctta ctgaagactt cgtaggcttt
    33181 ttcaatttca ctgagtttga aatagtgagt taccaatttt tctggttcaa tcttatgact
    33241 ttcaagtgct ttcaacaatt gtggagtcgt atttgtagat accaaaccag ttgttacatt
    33301 gatgttgcga atccaaagtt tatctaaatc gaattcaact ggtttaccat gcacaccaca
    33361 gttggcaacc gttccgtcta caccgataat cttttgacag aaatcaaatg ttgcaggaat
    33421 accaacagct tcgatagcga catcaacacc acgaccatct gtcaaatcat aaatttcttt
    33481 aatggctttt tcagggtctg aagaattaac cttatgagtc gcaccgaatg atagggcagt
    33541 ttccaagcgg ttatcgtcta ggtctaccat aatcaattta gctggtgaat agaattgggc
    33601 tgttaaaaga gcagccaatc caactggacc tgaaccaata atggctacgc tgcaaccagg
    33661 ttctactttc ccttttaaga caccaatttc atatccagta ggcagaatgt ctgacagcat
    33721 aaccaaagct tcgtctgaca agtcttctgg agtatggtaa agagtattat ctgcatgagg
    33781 gacacgtaga tattcagcct gcataccatc aatcaagtga ccgaaaatcc agccccttcg
    33841 tcttcacagt gggcataaat tcctttttta cagtagtagc atttaccaca ggcacagacg
    33901 caagaaatca agaccttgtc accttttttg aagttggaaa ctccttcccc aacttcttca
    33961 acaatcccaa tcccttcgtg gccaagaatg gtaccacttt ggcaagtagg aacatcccct
    34021 ttgataatat ggaggtctgt tccacaaaga gtggttttta caatacgcac aatagcgtct
    34081 gttggcttgc gaataactgg tttgtctaca tcaacaaaag aagcaagtcc tggtttaaca
    34141 taagtatagg cttttataaa gcactcctcc gtttttttat ttgtactatt tatagttcaa
    34201 ttgtaagcct ttttctttgt ttcttcaagc tttttttgtg atttttttaa ctttttattt
    34261 accagtaaag taccctatat aaaaaagcag aagctagtct ctaacttctg ctttctctct
    34321 tatgcttgat aacgttttac gccatctagg taggttgcta ccaattccaa atctttatct
    34381 aatacgatga agtcagcgtc gtagccttca cggatttggc cacagacgtc atcgatgtga
    34441 acggatttag ctgggttgaa gctggccatc atgactgctt catgcggatt cgcaattccc
    34501 cattcgacca cattcttcaa accatctttg agtttgagga tagaacctgc caagttacct
    34561 gtcgatttga ggcgtgcagt tccatttgca acgacaactg ggaattctcc caacatataa
    34621 tctccgtctt ccaatccccc agctgtcata cagtctgtga taagagcgat gttttctgtt
    34681 cctttttgtt tgataagaat ttcgcaagcc tttggatcta cgtggtgacc atcacagatc
    34741 aactctgcat aggtatgtgg caattggtac atggctccaa ccatacccaa ttcacggtga
    34801 gtcaacccac gcattccatt gtaggcatgc acccaaacac tcgctccagc atcgactgct
    34861 tttttggctt catcaaaagt cgcatttgaa tgtccaagag caaccgtcac accttcgccc
    34921 gtaactgtac gaacaaagtc ttccacccca tcacgttctg gtgcaagggc aattttatta
    34981 agcaagccat ttgccgcttt ttgccaagaa tgaaactcct caacacccgg gtctctcata
    35041 taagttggat tttgtgcccc cttaaaagtt tctgtaaaat atggaccttc ataataaatc
    35101 ccacgaatct tagcacctgt tgcttcttta taatggtttc caagattttc agtgactgca
    35161 agcaattgct cataagtggc tgttaaagtt gtgggtaaga aactggtaac accggtacta
    35221 agaagtcctt cactcatagt atgcaatgta ccttcaatgt tgttgtccat cacatctaca
    35281 cctgcatatc catgaatatg agtatccaca agacctgggg caatgctata acctgtatag
    35341 tcaatcacct cagccccttc aggaatctgc tctgcatgtt ttccaaactt gccgtccaca
    35401 agttccaagt aaccacctcg acgaactccg tgtgggtaga aaaactgatc cgctttaata
    35461 tagttaggca taatgttaac ctccttaaaa gattgattct acaatttatt atgtcaatta
    35521 cattataaac ctttcttttt tatttgtaaa tggtatagac ctattttttg gagatatttt
    35581 aaaagagctg gatttctcca actcttctct tttttaatac aagttatttt gatttaaccg
    35641 gcttgtcttg agctgtctgc aaagctgtgg caatcgtatc tgcatacaat tttgctcctg
    35701 cttcgatagt gctactctca ctcccgaaat gaacctggtc tgttccagcc caaatttctg
    35761 gatgctcttt cgcaacttga ttccaatctg ctatcgtaat gtaaggtgtc ttctctgcca
    35821 attctctcat ataggcagca gccttctcaa cgatggcata ggtctctttt gtcttatctc
    35881 cctcataagg agtcaccaaa atcatatggt gtcccttagg aagatttttc acgatactgt
    35941 cccagtcatc cttgtaattc tcaggattat ttaccccagt cgcaatgacc accgtcttag
    36001 gtaaaaattt attctggcta ttatttagca tgatttcatt tgcggtcttg gttgttacgc
    36061 tgacctgcgc gttaatctgt gctccaggaa gagctgtctg tagtgctgta tttgccctta
    36121 aagccactga gtcaccaatt aacatagtgc catcagcaat tcccaaactg tttgcatctg
    36181 cccgttctgc catcaccttg gtctggccaa tatttgttgc agcttgcttc aagccattga
    36241 cagtcaagtc tgtctcaaac gctcccactt gtggtgccaa caaggtcacc gtacagacaa
    36301 tgatggtcaa aattcctgta cttgctacaa ggattgtatg ggtataaggc aggggacgaa
    36361 gggtttggac aataggtgtg ttctttcctg caatccaagg ttccaataca tagaatgaca
    36421 gactggcaaa gccataagaa caaatcagag tcagtaatac agcaagaaga tttgatgtca
    36481 actgtgagaa aatgatatag aaaggccaat ggaaaagata aaccgcatag ctagtatccg
    36541 ctaaaaagct gataatcttc ggctcctgta tatgatgtgt cttttcatgt aagacacgcg
    36601 ccgccagaat catggcaaga gctacaagac tggcaagcaa gaagccgata agataggcaa
    36661 aaagataagt gaatttgaca aagaaagtca aaagaactag gaaaccaaag cctcctccaa
    36721 aaactaccaa agtctttcgt aaatcccaga ttttatccaa ctgcttgacg agggaagtcg
    36781 tctgacgaac gcctacaata gttgctaaca tacttcccaa aaagaatgga tagacatgag
    36841 ttaaactgga gaaataaaca gaagaataag aggtcactag aaaactacca ataaacatgg
    36901 agaggaaact gatcaagaag gcagcagcag ataagagaaa gaccatcccc ttcaactgac
    36961 catttgattt agcttgtttg gataagaacc aaactgccaa tccccaaaga atatagtagt
    37021 gaacctcaac tgccaaactc caattatgaa caaacaaatg aggaatgaac tgagattcat
    37081 aactcccacc tgttaggagt tcatagaagt tggtcataaa acctaagacg cccgcaatct
    37141 ggccaccaat tccagcaaca tagtcttggc gaaccaagaa agtaaaaggc atggtcacca
    37201 agaccatcaa aaccacaggt ggcacaatcc gataaaagcg tcttctaaaa aatcctatca
    37261 aatcaatctc atggttttta gaaaattctt caatgagtag agctgtaatc aggaaacctg
    37321 aaaatgtgaa aaagacatct accccgaaaa atcctccagg aaagatcgtc tgaaagaagt
    37381 gatacaagag taccaaaagt aaacctgtaa tcctaaccaa ggaaaaccat ttaatgcgca
    37441 tacgagttta ttcttccttt cattgtacac tttattctat caaaaaaaga agaaaaatcc
    37501 taagagaaaa cttaggattt ttagcttata tcaattccat tttagaaatt acgtcctgac
    37561 ttattatagc catatttttc cacaaaatac tcacggaatt ccaagagatt gtcatccatg
    37621 atggcttgtc gcacttgctt catcaagtta agcaagaagt aaagattgtg gtagctagtc
    37681 aagcggatac caaaggtttc atcagccttg agcaggtgac gaaggtaagc gcgtgtatag
    37741 ttattacatg tgtagcaatc acactcagga tccagtggcg taaagtcctc agcaaactgg
    37801 gcatttttca caaccaaacg tccttgactg gtcatacaag tcccgttacg agcaattcga
    37861 gtcggtaaga cacagtcaaa catatccacc ccacgaatga ccccatcgat caagctatct
    37921 ggcgctccca cccccatcag ataacgaggt ttattttcag gcagcagttg agttgtaaag
    37981 tccaagaccg cattcatctc ttcatgggtt tctcccactg ccaaaccacc gatagagtag
    38041 cctgagaaat ccatgctgac aagatcatga gctgattggc ggcgaaggtc ttcaaatcct
    38101 gcaccttgca caattccaaa caaaccttgg tcatgtggac gacggtgagc cttcaaacca
    38161 cgctcagccc aacggctggt acgctcgatc gatttcttaa cgtagtcata aggttgataa
    38221 aactgaggac attcatcaaa ggacatcatg atgtctgaac ccagattatt ctgaatagag
    38281 atggcttttt ctggggatag gaacatctta gaaccattta gatgattttt aaaggttact
    38341 ccttcttctg tgatattacg gctatctgct aaagaataaa cctgaaaacc accactatct
    38401 gtcaagatag gctggtccca attcatgaac ttgtggagac caccagcgcg tgcaatgagt
    38461 tcatctccag ggcgaagcca gagatgatag gtgtttgata ggataattcc cgaacccatc
    38521 tccttcaatt cttcaggtga ctgagttttg acagtggctt gtgtcccaac tggcataaac
    38581 ataggtgtcg gaaaggtacc gtggggagtg atgatttctc ctagacgagc tcctgtgtgt
    38641 ttttctttct taatcaaacg atatttgatt ggtgaatctg acatttttta cctccgaagc
    38701 tgggaaagac agtcccagtt catacagtgt gcccaaggac acactgtatg attttatcaa
    38761 aaaaagtagg aactgtcacg aactatgtag aagaactatg gtataataag agaatgaact
    38821 atccaaaaat tgatttaaaa acaattcgtc aggagtcaaa acattttcag gctgacaccc
    38881 cccgtctctt tctcctctat atccttccca gtatgctggt catcttatct agttttctta
    38941 atcccttatc tcggatccac gggactgttt tagaacagcc atttttcagc atacttggcc
    39001 aaatacttca agcctacctc tttcctctac tagtctcctt tatcgggact attcttttga
    39061 ccagttccgt ctatgcaaca ctgacactca tgaaagattc taaaacggag ccatctgtaa
    39121 aaaacagcct agctctcttt gatgaggagc gcttttctca aacctttttg accctacttc
    39181 tcaaacgttt ctatctcttt ttatggagta tccctaattt acttgggatt tacctcctct
    39241 tttatagtag ctttttagcc aaaaaattcg tcaccctaca tcctgagttt ccaaatttag
    39301 ctctctcatc agttgaaacc gagcgtttcc tcatggtctt tggactctac tttcttgcaa
    39361 gtctcatctt gatcattgta ggaaatatcc tctatattcc acagtattat gcctattcac
    39421 aggtggaatt tcttctttgt tatagtctag acctaggaca ggtcccacca agacgaatcc
    39481 taaaaactag ccgttccttt atgaagggct acaagttcca gcactttgtc ctagatttac
    39541 agcttcttcc ttggtacttc ctcaattgga ttacctttgg cattgctagt ttttcactcc
    39601 taccttatat ccaatgcaat aaaattatgt tttaccgagc agtattggct cgaaaacgtc
    39661 caaaagcttg aaggtttttc ccctcaagct tttttctatc aatgagtttc tccgcctacc
    39721 aacttgaggt cctgatctcc atgttctatc atagcgccga ttgctgcttc tatccctcgc
    39781 cgaatatcca ctaaactcat agctggagta gtcggtctgt tcaccacctg ttccatcata
    39841 taaggaatat gcataaaacc tgccttaaaa tatggaaatt tcttttctac caaatagagt
    39901 gcctgataca tcaaatggtt gcagacaaaa gtacctgccg tattggaaac agaggccggt
    39961 aagccctctt ttttatagct tgaaccatcg ctttaatcgg caaactacta aagtaggccg
    40021 aagcaccatc tgggcgaatg ggacggtcaa tcggttgatt atcttcgtta tcagaaatgc
    40081 gtgcatcgtc ttgattaatg gccactcgtt caggtgtcaa actagttctt ccaccagctt
    40141 gcccaataca aaggacaaag tcaggttgat aacgattcat ctcttcttcc aatacttgag
    40201 cagatttgtg aaaaactgtc ggcacctcta gccaacggac ctcagcacca tggatttcag
    40261 ctggtaaacc tttaatggcc tccaaagctg gattgacctt ttcccctcca aagggctcaa
    40321 aacctgtcac taatactttc atttctaact cctcaaaacc aatttattta ataaacggtt
    40381 gagctctgtt ctctcagact ctgttaagat actttccatc tcttccttaa ccttgatatg
    40441 ttgcagaggg ggattcacca ctaactgctc tttggcatac ttcgtagcct ctaccaacac
    40501 ttctcactga ttttcaggat tgcgatgacg ctccaccaaa ccttccgttt ctaaaatctt
    40561 gaaatgtcgt gtcaaagcag cctgatcaat cttcaaacgc tcctgaactc ccatttgatt
    40621 acagggagaa ttctccagca aaaacagtaa aatctgatac cgtgtcaaac taatcccaag
    40681 ccttttttca aataattgcg tgctcgcttg ctcagacaag cggagttgat aaagtaaatc
    40741 ttgaatctct aacatctctt ttctcttttt cttgattcat caatagttga ctaatcaagt
    40801 ataatgtaaa gtaaaataga ttgcaagaat gttgcttgag tcattacaag attcttactt
    40861 cttccattca aattgacaaa gaaaaaaacg aacgagaatc gctttccatc acgaaagcta
    40921 gatctcattc gtcaaaatga tgttatcaag tcgggtttat ccattcattg aaacgtgaac
    40981 gtgatcatag tgattttctg tcacactacc acggtctggc attgggttcc aagtgttagc
    41041 tggcccatat ttgctatcga atggagcata gaaacgttgt ttccagatga tgtaactaat
    41101 gccacggctg gccatgtttt gaatagcata ttccgcaatc ttatctccta attctgaact
    41161 ttctggtacc ataaagtcga tagccaaacc ttttccatga tctccactgt ctcctggacg
    41221 ataaccacta aaggatgtaa tgccaaacaa gttagcaatt tcttctttaa aggcagctgt
    41281 ttgtggttga aggcctgcat tttcagattt tgctactgca agtccagcat aatcgggcgc
    41341 agctggagcc tcgtaagttg ttgaaattat tttcgtctct tctggttgat aagtagaaac
    41401 tgctgctgta gctccatttg atgatgctac ttcttttgct tctgaacttg ttgtagttgc
    41461 ttctactgct gatgcagctt gagggcttgc ttgtgtttcc tgcttctcag ctggagtcgt
    41521 ttcctgagga gcttcttctg caactacact gcttgtttcg gccgtttgct cctctgggac
    41581 agaagtgccc gtagatggtg ccacttcttc agaagcaatc actgtctttg taacttctga
    41641 acttgatgct acttcttttg gagcttctgc aatcggttga gaaaggtctg caacctgaac
    41701 agtttgatca tcaacggtca cttgattagt ggtcaaatct gctgtcgcag ttgtcacttc
    41761 ttcactagag tctgcttgag gtgtttggat ttcaacttct gttacttctt ctgcttcatt
    41821 gacagtcgtt gtcaaaacag tttctgggaa aatcaagtcc atattagtga ttttgttcag
    41881 attcgcaagc actgtgacat ctacacccaa agcttctgca atggtgctca aagtatcacc
    41941 atactgtact gtataacttg ttttgttgtc cgttttagtc aaatcgtttt ggatttgctc
    42001 tacactacgg gcagtccaaa gaacttcttc tgcttgagtt gccaatactg gggcaaatga
    42061 caaggcaact gttgacgcta ataacattct tttattcatt ctttcaaatt cctttcaaat
    42121 gagtacctgt ctatgataac acaaaaaatg cagaaaaaaa gccctctcgg gcctatttaa
    42181 caaaattgtc tattccttgt aacaaactag gttacttgaa ataatttgtt aggtctctgt
    42241 cacaaaactg acacaatctt tttgtcgctc agcctcaaaa atacgggaaa tatctgctaa
    42301 cgcttgaatc ctgtgtttcc cttcataagt cgactctaaa aagttgatac tttgaatccc
    42361 actattctgg gcaaattcca catccagagt ccgatcccct atataataag tattatcaga
    42421 attcaactga tacttattta gcagataggt agccgcttct gggcttggct tccgcacaaa
    42481 gccactctga ctggttaaaa tctctgtaaa ataggattcc acccccaagt ccttgagaat
    42541 ggtaaaagcg ttgttcccct tatgagtata tataaactgc tgaattcctg attcgtctgc
    42601 ccaagctagc acctcacgcg cacctggcat caaaactacc tgagcattct tctcagccat
    42661 actctgggca cgcacctgat ttagcacctc aacatccaga tttctatctt ctgccacccg
    42721 cacaagcaaa tcttgcaccg aatacttgaa gataaactct ctcaccttct ccttatcata
    42781 aggaatagaa aactgagcaa aagtctcctc aatccctgat aaaatcgctt cgtaagagtc
    42841 caataaagtc ccgtctaaat cccaaataaa agctgttttt tgcatttcct atcctttcaa
    42901 gatcatatag cgctggtaac gatagcgtag aaataaccag cgaaaaccat tatccaagag
    42961 agaccctgcc caaataccag gtaagcccca accaagcaca atccccatca gatatcctgt
    43021 tccaatgcgg atacaccaca ttcctatact tgtcgcataa aaagggaggc gtgcatttcc
    43081 taatccctgc cagactgccg tatagatgac tgttcctgtc gtcatagagg ttccaagtag
    43141 tgaaaacagt gtcactagaa cactagcctc caccgctaga gaatcagtcg tatagagatg
    43201 agttaatggt acacccaaga catatatact aaaggacagg ggcaacatga ggaacagaga
    43261 aagccaaaag gtttgtttac tcaaactagc gactcttttc caatcatcct ctccaactgc
    43321 tcgggccaac agcatgaccg ttgccgtagc gacgccaaag gcaggcatat agttaaactg
    43381 ggtcaagact tctccgattg cattcccagc aactgcctcc gtcccaaaag aaacgaccaa
    43441 ggcaatgatc actacatctc cagccctcat cataagtcgc tctccagctg ctggtaaagc
    43501 caaggtcaac agttccttat ctaaaccaaa agttggcttc ccataaggca gttttaattg
    43561 tgaccacaaa atcacaagac caaccaaacg agacagaatt gtcccccaag caacaccagc
    43621 tatccccata tccagaacaa aaatagctag acttgaaaaa agaatattca aggcattgga
    43681 taaaaaacta acatagagag gcagacgtgg attatgcgtt gcacgaatca aggctcccaa
    43741 actagtcatt aaacctaaga gaacaatcga tccgcctacc aaagatagat acagtccacc
    43801 actctcagct acatccctct ccgtccccaa aagtcctatc atctctttcc cagcgaagat
    43861 ggacaaaaat cctaaaagga aacttaatag taaggtaatc ttcaacgcct cagtcacatg
    43921 ataggccaac ttcgactggt ctttctgccc tatgcttttt gaaataacac tggaaatagc
    43981 agctcccaga gcgatgaaaa tcgcttgata aatggtgata atattaccag ctactgaaac
    44041 ccctgaaata gctatcaatc ctaaatgagc aaccaaataa ctgtccacca ttcccattag
    44101 catctgcaaa aagttttcac ccatagctgg caatgcaata ttaagaatgt ctttattttt
    44161 cttaaacaat ctctcctcct gatgaaaaga aactcagttg gtttcccaac cgagtttgct
    44221 ccctctgtct taaagtccta aataagcctc aaccgctgct tgcatgtcag cagctgccac
    44281 tgttgtcttg tgacgaattg gagctatttc aagcccatca actgctggtg gcactgcaac
    44341 gcctgagatt tcatgtaatt gagccaaggc ttcaaagtct gttaaacctg cttttccagt
    44401 tacagcttct actgcaacta ctgggaactt gtatggacta gctgttgaag caatcactgt
    44461 cttagttaca tctccagtgg ccgattggta ttttttataa actgctgaag caacagctgt
    44521 atgagggtcc tcgatataag aatatgactc acaaacacgc ttgatctctg ctgccgtttc
    44581 ttcctcagtc gcatattcag ctgcaaagag gtccaaaatc tctgcatcaa agtctgtcaa
    44641 cttatattgt ccttgcgtgt tcaaagcatt catgagttca gctgtctttt cagcattatt
    44701 tcccaaaaga tggaaaatca agcgctccaa gtttgaagat accaagatat ccatagatgg
    44761 gctggttgtt accttaaact cacgtttttt gtcatagaca cgtgttttaa agaagtctgt
    44821 caaaacattg ttgtcatttg aagcacagat caatttacca actggcaaac caatttgttt
    44881 ggcataaaag gcagccaaga tatttccaaa gtttcctgtt ggtactgtga agttaacctt
    44941 ttcaccagct acaatttcac cagtcttaac caattgagcg taagcataaa cataataaac
    45001 aatttgtggc accagacgac caatattcat agagttagca gatgaaaatt gcaacttgtt
    45061 ggtagtcaat ttttcacgaa gagccacgtc gttaaacatg tgcttcacat ttgtttgcgc
    45121 atcgtcaaag ttaccatcaa tagcaataac atgagtattg tcgccagtct gagtggtcat
    45181 ttgtaactct tgaatcttgc tgacaccatc ctttggataa aagacgataa tctcagtacc
    45241 aggcacatcc gcaaaccccg ccatagcagc tttccccgtg tcaccagatg tcgctgtcaa
    45301 gataacaatc ttgttctcca aaccatgttt cttagcagca gtcgtcataa agtatggcaa
    45361 aatagacaag gccatatcct taaaggcaat cgttgaacca tggaaaagtt ccaaattgta
    45421 ttgcccatct aatttcacta atggtgcaat agctggagta tcaaatttgc tatcgtaggc
    45481 attgttgata cagtagttca actcctcaac tgtaaagtca tctaaaaatg ctgacaaaac
    45541 tagcttagca acttcctggt aagaagcatc tttcaatttg tcaaagttca aatctacctt
    45601 tggataagta accggtgtaa acaaaccgcc gtccgtcgcc aaaccttgca aaattgcttg
    45661 gctggcagtt actgtattgt tggcatcacg cgttgattga taaactaatg tcattactct
    45721 ctatccttta tctatagtct cgtccattat atcatgattt ttcagaaaat tctcccttta
    45781 taagagaaat tataggctca attcttctct caaaggctgt aaataggtca tttcttcctt
    45841 atttctcacc actagtccct cctcagctag taggagtaag tctttggaaa attcaataat
    45901 cgtagtttct tcctcatctg taagattttt cttagaaaat tgtctcctta aagacttgta
    45961 atcataacca aatactttaa agaaaggtgc tgtttctaag taagcttcta acttgtctaa
    46021 attaaccaat aatcccaagt gaaaagctgc agaagcaaaa gtcctatcaa gtggctgtgt
    46081 acacacacta cgaaactcaa ctgttcctcg agtcgttaag tcttggtact ggtaactacg
    46141 atgagtttca aaatccttct cttgggggta aataataacc tcatccccat tcagagcaaa
    46201 tgcttggatt tcaggcgtag ccaaatagtc cccagcctga ataggataaa aataataggt
    46261 ctgcccatca cgttccgcag taaaaatcgc agaatgattt agatagtcaa aaaaatcagc
    46321 ttcatcatta aggagtctag cattgacccc aacattctct ggatagatac catgcataga
    46381 ttcttcccag aaaatatccc ttgaaatttt cgtatcccaa tccgcacccg aaaactcaga
    46441 gtttgcaaat aaataagcct tagccgcttc aatttgagta aaagcattaa tcacccgcaa
    46501 gtagttggtt tttgaaatat ccagctgaac ctggctccca cagataaaag taccgtattc
    46561 agggaaatga tgtaaatctg atttaataat atttctactc aaattcaaat aatccatcaa
    46621 catctgatag cgtggataag ccactggaca attctcattt ttatcccagt tgggatggat
    46681 accacagcca acaatagcat gatttgattc agctaacttt ctctgaatta cattcatata
    46741 attattgaaa cgattttcga cctcttgaat cgtttcagcc ttaccaaatg caaactcaat
    46801 cgttgtatag gaaacttcaa ataaaatagc atcctgactt atcggatcta ctaactggat
    46861 cagattgcca aaatcatcta cctttgctac ggtgagatcc aaagtagaaa ctaaataatg
    46921 aaatagatcc tttataactt caacatctgt agcatcccct tctaaacttg caacaggata
    46981 ctccaactca attccgacaa acaattcagg attttcttta atatttttca aataccgatg
    47041 ttttaataaa tcgatagaac aagacatact cccctacact ttcttaatct aaataaaatt
    47101 tgaataacta taattatacc aaaaataata taaaaaagga acgaagaata acaacgttcc
    47161 taacactata ctataccggc ggccggggtc gaaccggcac gtccttgcgg acactggatt
    47221 ttgagtttga ttctatgata ttcttaactt cataaatcta gtaaaatcaa attttcaata
    47281 aattatttct atcgcaaaaa cgatagattt tttcttttta gtaacatttt agtatttgat
    47341 agcttgctca ctatatttaa atactgttct tttctcttca aaaaatacct tacacttttt
    47401 cacttcttca tcataggcag taaagagttc ttctatttcc caatcgttat aactataatt
    47461 tgatttattg ctaagatttg taagcaggtt cattaatgaa aaaattttct ccactcttgc
    47521 agttgatagt ttcttaaagt atacttcctt gtcattactt gtatcagtag aggaataatt
    47581 gaactcttgt tttagattaa ctgtttttat agtaatagga ctagtgaaaa attcctttat
    47641 ttcttcgccc ttttgttcta acgccccaaa aagttcttta atatcagctt ctgaaaaaga
    47701 atactttgat ttatcacttt gatttctcag tatatttaag attgaaaaaa ccttagtcat
    47761 ccttgcttct gacaatcttc taaatttttc atttctagtt tccatagttt ctccaataag
    47821 taaattttat ttctttatcc tatatattat catatagcga gatttttttc aaatattgca
    47881 ttttatgatt ttgtgtagta taatatccta tatagaggga tatcctctaa atataatacc
    47941 caaaaaggag gggttcttat gtttaaagaa cttatcgaat ttgttaattc ctcaacagag
    48001 ggacagttta aagcctttca agtcaaggct aatgcaataa caggagatgt tatcatctct
    48061 caaaatgtaa cacctatcac tgacgcctta aaaaatcgtc taggattaaa aactgtgcaa
    48121 acctctttag caaggaagtt agcttacgct tctactcgtc gccactataa agatggtaca
    48181 acaatgatgg aagacatctt agctggcaag acacgtcgcc atgcaaacag ctacatctag
    48241 atgactgggg gagctaactt ctccccttta tcttttgatt gaaatagaaa ggagtgacat
    48301 catgaagagt ctctataaat atctttttta tttgttcttt attggatttg ctggcacact
    48361 ctgttatgtg ttgcttttaa caaatgcctt ttcacctatc tttgaagctg ctacaatatt
    48421 gatggagatt atagttgtta tttttttaat aatctgtata gacctgattg cttcccctac
    48481 tggttctgct gaggagaata taaaaaatga gaatgttaaa tcaaacaatc cgtgtgaaga
    48541 gtaaataccc ttacttgatt cgtcctcgaa atattaccat tactagacta tctatccaag
    48601 tttttctttt tttactattg gtatcttcat ggcttgctgc aatcccattt attgcacgtc
    48661 tagtcttttc catgtttttt ataagtcttc tttttttagt agagaggttc tttcattctg
    48721 atgttataga aaaattgaga aacaagctca atatcagaga agctttgttt tacatgttaa
    48781 ttagtttaac tttatatgat gatatagata atgaagtagt agatacagcc gttttatatt
    48841 ttgacgtttc tgagaatgac aaggttatta tctgtgtccc attatttggg aaccgttatc
    48901 tgaaaacctt gaaaaattta gaggaatatc tctgtcccac attggggttg tccttaattt
    48961 ttaaaaaaga agagattgat aaaatagtat atgtgttagg gaagatagaa gaaattgaac
    49021 aatacgtttt caatactaat acattaacta gggagttttt taaggatatt cctagtccaa
    49081 taatcaagct atcaaatacc caacaattct ctctgaaatc gaatactaat atcggtattt
    49141 atggacgcac tggaacaggt aaaacaatag ctctccaatg gtatttattt aatgctcttg
    49201 ctaaagggtg cggaactgtt gacggtactt acttaggcat tgtagacgga aaaggggcag
    49261 acttatatgc attagggaag ctacttgaag aagaaatagg aaatcaagtc actgtgggta
    49321 cttctccaac ctctttagcg aaattgtcaa gggaatttgt agaaattatg aacgaacgtt
    49381 ttgaggttat caagcagaac agttccctaa atgctgatgc ttatgattta ggaatgatac
    49441 ctaattttct atttgtagac gaattggcat caatacgcga tagttgttgt ggctctagca
    49501 aacaggcgaa agaactttgg aatgaaattc tacaaaattt aggattgatt gcccgtaaag
    49561 gaaggcaggc tggttgtcac ttagtattat ccacacaaga ccctaatgct gagaatattc
    49621 cagtagaatt gagaaatcaa atatcggcag ttttatacct tggaggtcca ggtgctgata
    49681 gattgaagat ggcttttagc atgtgcgaat tagaaaacgt tcctactgta tccgatagaa
    49741 aaggagaggc tctcttttat gctgacggtt taaattcagt tgagcctgta ttgacaatcg
    49801 ttccattcgt tgacgtaaaa accaaacaag aatttttaca gatagttaaa aatatactgc
    49861 caaactacta atgacggtat ttttctctgt tggaatagga attcttttca atagagaaaa
    49921 agagccaacc gactgcattg caggaggtaa gaaagaaagg aatttatcat gaaattaaat
    49981 gattttttga aacccgaact actaggcaat cgcttctttg ccgtgaaagg gtatacagaa
    50041 gtattagaca gagagactaa taaacccgta gctttacgac ttaatgtgtc aattcaagat
    50101 gagaattctg atttctttat ggagatgata caagtcaaaa taaatacatt atcgcctact
    50161 gcttctgttc aagagatggc gaacaacaaa acttgtcctg ttagtcttaa agatttaaac
    50221 gtagggcaat tcaatggaaa tttgtggttc gcttgttctg atgttttacc tgtaacaaaa
    50281 tagctaagat taaataatat ataaaggagt tttacaatgc aaacttttaa ctacgatgat
    50341 tttaagaatg aaaaggggat tgtttcattt tctgaagcag aacaaatcta ttctagtctc
    50401 cttaattctt ccaatcaact tgataaagaa tttcaagaag aatggacaac atttgtactt
    50461 ctatgcgtag agtatgcctc tgcacgtggt aaatggctca cactctcaag agaagagaaa
    50521 cttgccaatg atgaatctag aactgttact cacaataaag ttatttatca actaaagatt
    50581 ttaaaaggtt tagcaagtga acagggcaat gatgttgctt ggtttgaaca atttaacgat
    50641 gacagaaaac gtattggcga ctttgcttgc tatgtagctt atatctatgc cttaaatgct
    50701 cgatagacaa ttagaggata ttatagctat atattactct atgtctgata ttcatggaaa
    50761 ttattaaata acatcttaag aataattaat tctatttatc tatcaccgaa acaatgtgct
    50821 ataacttaat tcgattctta gactaatatc aaaaataaag aggggaatat atatgaagac
    50881 gttattaatt ggtgatttac acttaaaatc tcaactgatt ttacccattg ttgacaaaat
    50941 tatccaaaca cataatatta agagaatcat ttttcttggt gattacgttg atttacatgg
    51001 tcaaactaac aatatccaac tttatgccaa agacctcact tttttatact cttggaaaat
    51061 agataaagag caaaacggaa tagatgtaat taatcttata ggtaatcatg atgcttatta
    51121 tttactggga gaacaagctc ctttctcaat tcaaaaccta gaggtctttt tcgcagttaa
    51181 agaattgttg caggatttga aattacaagt agcttatcaa ctagatgatt atttagtcag
    51241 tcacgctggt ttcaatctga tatttgaccc aaaagaatgg cattttaacc tctataccaa
    51301 agagcatgaa gaagaattag atattctagc ttatacaata ggaccaatgc gtggtgggaa
    51361 agctcttggg gggtctcctt tatgggcaca ttttagagaa ttagaactgc ttcccaacca
    51421 agactttcct aaacaaattg ttgggcatac ccctaaagaa tctattgata tttctaaaaa
    51481 tgttattggt atagatactt tttcattata tattgacaaa gataataaat atcaatttat
    51541 tggtaatgga gatttactcg tttatgacca aggacatttt gaggtcattt caacagactg
    51601 ggcaacagac aaaatattaa aacaattacc acgactataa atttaatagc tacttctcat
    51661 catgtaccta agcaaaactg ccgactaagt cggcaagctg gaagtgtgtt tagcggagcg
    51721 gtgcttagtc acatgataga agtagggagg agcaatgctc ctcttagttt atttattata
    51781 tagacaatct tttggcgaaa gccaacctaa aaggaactat tttttatgac ctcatataat
    51841 aaaaaaatag tccgcacttc ttcctatatt gaaatttggg aatatgaaaa gccaatattt
    51901 tcaaaaggaa aatccatttt agatactgat attaaaagca aagaaaaatt acaacgtaga
    51961 acatttgatg aacttacacc tgaagaacaa gaacaacgtc tggagcgtat gaaaaaaact
    52021 cgcttagaag caaagtggaa cttactccga ttagtcgatt gtaattatga tgacaatact
    52081 tcatttctaa ccctgaccac taaagaaaat attagcgaca gaaaccactt caaagactta
    52141 ctaaaaactt ttataaaacg ctttaactac cacatcttta ataccaagaa aagtaaatta
    52201 aaatatttaa cagtattaga aaagcaaaaa cgtggagcat ggcatgctca tattctgctt
    52261 ttcagcgttc cttatgtacc acaccgtcaa ctcttggaac tttgggaaca tggagcagta
    52321 cggataaata aagttgatgt agacagcaaa gaaaatcgcg gtcgatatgt cacaaagtat
    52381 tttgaaaaag ggattggaca agaattgttg gaaaacttcg gaaagcaagc ctatttttca
    52441 tcacgcaact taaaaaagcc tgatgaagat agattttata cttatgaaga ttttaattat
    52501 gatagttcag tcgtactata tgaaacggaa tacattagta aagtctataa agacggtcag
    52561 tatttcgata atcatgtaaa gtataagaaa ataaaactag attaataaag gagtaagtta
    52621 catgatagca actgttacta agaatgacct agttgccctt ggtttctctg agggaacatc
    52681 taaacgtatt atccgccaag ggaaagagct actgataaca cgaggcttta cagtctatca
    52741 gaataaacga attggtacta tacctgctac tattgtaagc gaattactcg gttttgatgt
    52801 tcaaaacagt accctcaagg agtaaaatat ggcaattaga aaaggtaaag acggtaattg
    52861 gatagttgat attagcaacg gttttgaccc aataacacta aagcaacgta gaattgtcag
    52921 aaagggctat aagacaaaaa aagaagctat tgaagcagaa cactacttac gaagtgtaga
    52981 gttaaaagaa cgcttctatg gggctaaaat aactatcccc atactatatg aactactaaa
    53041 ggaagaagat agtataaatc atcgaaaagc aagctatatc aatacacaag ataataatta
    53101 caacaaacac atcaaagatt atttttctat ggtatataat gtcggaaaac taacctatga
    53161 agacatctac caatttagag aacatcttag gcaaaaagta gctaaaaatt ctgataaacc
    53221 tttaagcaca aacactatca acaaaatcat gattttactc aaaaagattt ttgatgttgg
    53281 tttgcgaaaa ggctattaca cctccaatcc agcaaatttg ataaaaaagt tgccaatcga
    53341 aaaaacaaaa atgcagtttt ggacagtcaa agaatttcaa cattttttaa ccttgtttga
    53401 aactgaagaa tataatatca agttactctt tactgttcta ttctttacag gactacgact
    53461 tggggaagca ttagcactaa catggcaaga cattgatttt acaagcaata caattcacat
    53521 tacaaaatca gtttatgtaa acaaaggaat aagtcatgtt agcacaacaa agactaaagc
    53581 tggaacaaga agaattatca ttaataagaa attgagccat gaactacaac aatggcaaca
    53641 gaaacaaaaa cacctattag aacaatttac tagtgatagc atgaccctac aagtgtttca
    53701 aggctcacct attacaatta caaaaaatgc agttgaaaaa caatataaga aaatacttga
    53761 acgtgatagc acactaaaaa aaatacgcat acacgatttt aggcactcac acgcttccct
    53821 gctgattaac caaggggaag attatctagt tgtaaaagag cgactaggac atgcttctat
    53881 aacaaccacg attgatacct actctcactt gtacccaagt aagcaaaagg atttagctga
    53941 taaactagat gatttactat aaagtaattg agttttataa atggaaagtt tataattaaa
    54001 tcatggatac atcacaagta ataaaagcac atgaagtagc taaaaaagca cactttggac
    54061 aaattgatag agcaggaatt gactacatta aacaccctga aacagtagat agttttgtcg
    54121 caactgatga agagaaagct gccgcctatc tacatgatgt aattgaagat acttcactaa
    54181 ccctactaga cctaaaaaag gaaggttttt caaaaaacat tatagaagcc gtcgatatac
    54241 tcacaaagaa aaaaggacaa gattatcaat cttatctcaa tctagtaaag aaaaatgaac
    54301 tcgctagagt tgtaaagttg gcggatttac ggcataattc agatttaaca agactaccat
    54361 taattactga aaaagactta gagagaaata agaaatacag ttctgctatt agatttttaa
    54421 gagcaaagaa aaaaagttag taactaaact ataaaatttt ataaagagaa aacaaaagac
    54481 aaggcttata aactttgtct ttattactat actggcggtc ggtctcgaac tggcatatcc
    54541 ttgcagatac tacaatttta ttaaaataaa taactataaa aagtgaaatt ttttattgag
    54601 aaaattttag actaggagta taatgtatct aaaataacta ttaggtggct gttatatgaa
    54661 taatgttgtt actacacaaa tttctattca acttagtcaa gagttaaatt ctttattaaa
    54721 tgctattgtt gaagaaaata atacaacaaa gactgacttt attagacaag cttttataga
    54781 gaaaattgaa gatatgtatg atattaaggt cgctgatgaa gcttataaaa aatgggttga
    54841 atgtagcaaa aaatctatct cacatgaaga aatgatgaga cgctatggct aaattatacg
    54901 caatatctga tatacatgga tacttggatg aattcagaga cgctctcaat aaagtaaatt
    54961 taaacgataa agataatcgc ctatttttac taggagatta tcttgataat ggacttcaat
    55021 cttttcaagt catttccaaa ataatcgaac ttgaggaggt ttatcctaat caaattatta
    55081 ctcttctagg gaatcatgaa gaatggtttt atgattggtt gattttagat aaacctactg
    55141 cttcagcatt tccagaaaca ataaaaagct tcttctctcc agagaaattg aactatattt
    55201 ttaaatcgaa tgctaacaac tttgaaacag atgttagaaa tgaaattaaa aataatatca
    55261 aattcaaccc atttataaac tggtttaaaa aacgatatag ggatgaacgc tattatgaaa
    55321 ccgaaaccca aatttttgtc catgctggca ttgatgaaga agcagaaaag ctttggaaag
    55381 aactaacgag ttcagagata tttacaaaca aatttcttat taccactggt agatttcata
    55441 aagctattat ttcgggccat attgcttctt gggaagtagc taaagataga agatacctag
    55501 gtaagattta ctatgatagt aaaagtcatt actttattga tggagatgta acgaatagca
    55561 aaacaatacc tgttctttac tatgatacaa ttacccaaaa atatcacttt ctataacttt
    55621 gaactgcacc ccaaaagtta gacagaaaaa atctaacttt tggggtgttt tattatgaaa
    55681 ttgagttatg aagataaagt tcagatctat ga
//
LOCUS       DAVDHZ010000009        54885 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000009 DAVDHZ010000000
VERSION     DAVDHZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54885
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.009"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            740..1861
                     /gene="mnmA"
                     /locus_tag="VUR46_000691"
     CDS             740..1861
                     /gene="mnmA"
                     /locus_tag="VUR46_000691"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET5456159.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVIAVADQISIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLNQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVAGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFMREMPEEFTLECTAKFRYRQPDSKVTVHVKGEKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2002..2457
                     /locus_tag="VUR46_000692"
     CDS             2002..2457
                     /locus_tag="VUR46_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5456160.1"
                     /translation="MTQQDFRTKVENTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEGAVVREVREELGVKAQAGQLAFVVENHFEQDGVYYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTTLPDWDGQLKHIHREE"
     gene            2467..4380
                     /gene="mnmG"
                     /locus_tag="VUR46_000693"
     CDS             2467..4380
                     /gene="mnmG"
                     /locus_tag="VUR46_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET5456161.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEAMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPVNIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4587..4679)
                     /locus_tag="VUR46_000694"
                     /pseudo
     CDS             complement(4587..4679)
                     /locus_tag="VUR46_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4733..6412)
                     /locus_tag="VUR46_000695"
     CDS             complement(4733..6412)
                     /locus_tag="VUR46_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET5456162.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKTP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6414..6647)
                     /locus_tag="VUR46_000696"
     CDS             complement(6414..6647)
                     /locus_tag="VUR46_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET5456163.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(7466..7618)
                     /gene="cibB"
                     /locus_tag="VUR46_000697"
     CDS             complement(7466..7618)
                     /gene="cibB"
                     /locus_tag="VUR46_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET5456164.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7620..7805)
                     /gene="cibA"
                     /locus_tag="VUR46_000698"
     CDS             complement(7620..7805)
                     /gene="cibA"
                     /locus_tag="VUR46_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET5456165.1"
                     /translation="MTNFDILDNQFLSLYENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7983..8666
                     /gene="tsaB"
                     /locus_tag="VUR46_000699"
     CDS             7983..8666
                     /gene="tsaB"
                     /locus_tag="VUR46_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET5456166.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVVPF
                     VEQIQKHLPRADYKETLPNAASLALLAWDKETDSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8663..9100
                     /gene="rimI"
                     /locus_tag="VUR46_000700"
     CDS             8663..9100
                     /gene="rimI"
                     /locus_tag="VUR46_000700"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET5456167.1"
                     /translation="MIEIKRIQQQPALAQAIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9090..10100
                     /gene="tsaD"
                     /locus_tag="VUR46_000701"
     CDS             9090..10100
                     /gene="tsaD"
                     /locus_tag="VUR46_000701"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET5456168.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10140..11446)
                     /locus_tag="VUR46_000702"
                     /pseudo
     CDS             complement(10140..11446)
                     /locus_tag="VUR46_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11722..12073)
                     /locus_tag="VUR46_000703"
                     /pseudo
     CDS             complement(11722..12073)
                     /locus_tag="VUR46_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12180..12473)
                     /locus_tag="VUR46_000704"
                     /pseudo
     CDS             complement(12180..12473)
                     /locus_tag="VUR46_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12716..13921
                     /locus_tag="VUR46_000705"
     CDS             12716..13921
                     /locus_tag="VUR46_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET5456169.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVVGVQDFKKEFCIPNN
                     KKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICHLKCRD
                     NFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLSEIIEH
                     RVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYD
                     ELLEKSSHG"
     gene            13914..14867
                     /locus_tag="VUR46_000706"
     CDS             13914..14867
                     /locus_tag="VUR46_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5456170.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            14877..16493
                     /locus_tag="VUR46_000707"
     CDS             14877..16493
                     /locus_tag="VUR46_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456171.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKKKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16513..17358
                     /locus_tag="VUR46_000708"
                     /pseudo
     CDS             16513..17358
                     /locus_tag="VUR46_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17426..18925
                     /locus_tag="VUR46_000709"
     CDS             17426..18925
                     /locus_tag="VUR46_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="HET5456172.1"
                     /translation="METRNLISYSLTDIFETDKIRIELLGEIYYKNIKLELHEFAGLY
                     KIYGISLIKNITGMFLIIIFDTKTKELKIFQDITTSYFNLYYTVYGGVFYYSTSLKKV
                     MKLSHVPVTLNNKKIQEFIRNGFILDSNTLVTEINKLEYFSYISVNNTLRICGIDYND
                     SNNFTKEQVLKNWDSMLRESILRVYSEAGEANITLSSGFDSNYILYTLANYTNSSINA
                     FCIGGEKGINEIPEVTKIAKFYGINLLVDTVMSQDLEYFPDIVWRLEGSLFECGVILQ
                     YYLGRLLFQKGNTSILCGESADEIMTFKYHSVNYNQFCNDKQKSVYFSYSDYPFYVTN
                     SIILKKNSLLLHSFGIHPRYPYKMSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLD
                     NINSVPGTTHLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNI
                     EENLEDDIERILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            18937..19686
                     /locus_tag="VUR46_000710"
     CDS             18937..19686
                     /locus_tag="VUR46_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET5456173.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDKKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19699..20871
                     /locus_tag="VUR46_000711"
     CDS             19699..20871
                     /locus_tag="VUR46_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET5456174.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSSTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            21267..22130
                     /locus_tag="VUR46_000712"
     CDS             21267..22130
                     /locus_tag="VUR46_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET5456175.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIGSWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKLLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            22416..22613
                     /locus_tag="VUR46_000713"
     CDS             22416..22613
                     /locus_tag="VUR46_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HET5456176.1"
                     /translation="MLNLQFAETMELTEAELETVYGGELGYNAVIPGGSWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            22681..23346
                     /locus_tag="VUR46_000714"
     CDS             22681..23346
                     /locus_tag="VUR46_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5456177.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23418..24644
                     /locus_tag="VUR46_000715"
     CDS             23418..24644
                     /locus_tag="VUR46_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5456178.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(24996..25073)
                     /locus_tag="VUR46_000716"
                     /pseudo
     CDS             complement(24996..25073)
                     /locus_tag="VUR46_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25144..25800
                     /locus_tag="VUR46_000717"
     CDS             25144..25800
                     /locus_tag="VUR46_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET5456179.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            25790..25999
                     /locus_tag="VUR46_000718"
     CDS             25790..25999
                     /locus_tag="VUR46_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET5456180.1"
                     /translation="MVSKYLLLAVIFSGLVAWIPRMIPFILVKYKGLPTIVERFLKFL
                     PVSIIFALILSRVVTGKVGNLPQIK"
     gene            26217..27047
                     /locus_tag="VUR46_000719"
     CDS             26217..27047
                     /locus_tag="VUR46_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5456181.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27201..28055
                     /locus_tag="VUR46_000720"
     CDS             27201..28055
                     /locus_tag="VUR46_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET5456182.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKSLFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            28155..29528
                     /locus_tag="VUR46_000721"
     CDS             28155..29528
                     /locus_tag="VUR46_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET5456183.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQRHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            29521..30582
                     /locus_tag="VUR46_000722"
     CDS             29521..30582
                     /locus_tag="VUR46_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET5456184.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            30584..31276
                     /locus_tag="VUR46_000723"
     CDS             30584..31276
                     /locus_tag="VUR46_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456185.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(31306..31875)
                     /locus_tag="VUR46_000724"
     CDS             complement(31306..31875)
                     /locus_tag="VUR46_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET5456186.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            32010..32624
                     /locus_tag="VUR46_000725"
     CDS             32010..32624
                     /locus_tag="VUR46_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET5456187.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVVIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            32674..34258
                     /locus_tag="VUR46_000726"
                     /pseudo
     CDS             32674..34258
                     /locus_tag="VUR46_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843414.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            34270..35556
                     /locus_tag="VUR46_000727"
     CDS             34270..35556
                     /locus_tag="VUR46_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456188.1"
                     /translation="MYKVLIVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEDLEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDGAGFVSYLGDKENWWIGLSKEK
                     QGSFTTPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKALFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTVHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSIKDISKDLFINPVYLGQSIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNIGYFYKVFRKLCGKLPKAYRKQVETIL"
     gene            35617..36150
                     /locus_tag="VUR46_000728"
     CDS             35617..36150
                     /locus_tag="VUR46_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456189.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            36228..36698
                     /gene="nrdI"
                     /locus_tag="VUR46_000729"
     CDS             36228..36698
                     /gene="nrdI"
                     /locus_tag="VUR46_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET5456190.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(36991..38253)
                     /locus_tag="VUR46_000730"
     CDS             complement(36991..38253)
                     /locus_tag="VUR46_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET5456191.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNKEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(38563..39021)
                     /locus_tag="VUR46_000731"
     CDS             complement(38563..39021)
                     /locus_tag="VUR46_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET5456192.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(39018..39458)
                     /locus_tag="VUR46_000732"
     CDS             complement(39018..39458)
                     /locus_tag="VUR46_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456193.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            39814..41763
                     /gene="mutL"
                     /locus_tag="VUR46_000733"
     CDS             39814..41763
                     /gene="mutL"
                     /locus_tag="VUR46_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET5456194.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(42088..42555)
                     /locus_tag="VUR46_000734"
     CDS             complement(42088..42555)
                     /locus_tag="VUR46_000734"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET5456195.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(42556..43761)
                     /locus_tag="VUR46_000735"
     CDS             complement(42556..43761)
                     /locus_tag="VUR46_000735"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET5456196.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMIENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIEKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQILKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANAYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(43781..44416)
                     /gene="ribE"
                     /locus_tag="VUR46_000736"
     CDS             complement(43781..44416)
                     /gene="ribE"
                     /locus_tag="VUR46_000736"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET5456197.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTWEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(44401..45501)
                     /gene="ribD"
                     /locus_tag="VUR46_000737"
     CDS             complement(44401..45501)
                     /gene="ribD"
                     /locus_tag="VUR46_000737"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET5456198.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCKILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPIGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(45634..45748)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            45905..46498
                     /gene="ruvA"
                     /locus_tag="VUR46_000738"
     CDS             45905..46498
                     /gene="ruvA"
                     /locus_tag="VUR46_000738"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET5456199.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            46508..47071
                     /locus_tag="VUR46_000739"
     CDS             46508..47071
                     /locus_tag="VUR46_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET5456200.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            47068..47745
                     /locus_tag="VUR46_000740"
     CDS             47068..47745
                     /locus_tag="VUR46_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5456201.1"
                     /translation="MMSNKNKGILIFAILYTVLFMFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(47882..48913)
                     /locus_tag="VUR46_000741"
     CDS             complement(47882..48913)
                     /locus_tag="VUR46_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET5456202.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLRLNPIFLPHS
                     LKGLDFIKDHPEARAENLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(49168..49851)
                     /locus_tag="VUR46_000742"
     CDS             complement(49168..49851)
                     /locus_tag="VUR46_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET5456203.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(49863..50807)
                     /locus_tag="VUR46_000743"
     CDS             complement(49863..50807)
                     /locus_tag="VUR46_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET5456204.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            50939..53770
                     /gene="uvrA"
                     /locus_tag="VUR46_000744"
     CDS             50939..53770
                     /gene="uvrA"
                     /locus_tag="VUR46_000744"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET5456205.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMTAFGVDMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVTNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGDQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINNILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            53763..54824
                     /locus_tag="VUR46_000745"
     CDS             53763..54824
                     /locus_tag="VUR46_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET5456206.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIVGIVKDMGLTRIGFEDEISVSYY
                     HRMQATFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACFISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMTLTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT        16321 a         9914 c        11775 g        16875 t
ORIGIN      
        1 ggctcaggtg cccttgcagt caacacaact gtagatggct atagagtcaa tgccaatggt
       61 gaatgggttt aagccgattc aattaaatca tgttaagaac atttgacatt ttaattttga
      121 aacaaagata aggttcgatt gaatagattt atgttcgtat tctttaggta cctatcttat
      181 gatttcagga agtgtcatta aaaaaacgac tccttttctc taacttgaaa aatagattag
      241 agaaaatggg ttgttttatt tattatagtt atttgaatga aaataagaag aaggtatact
      301 cacgtcattc acatgatctg tatattgact ataagtttta aaaaacaatt tttaagctct
      361 ttcttgtctt ctctaaccaa gcgtgttata atgaatactg ctcaagcgat cttcaatcgt
      421 taagcacaca cgaccttcaa tcgtgaacta gtcatttcgt ttatctttta ttacgtcgtt
      481 aactcgaaat aagatgcaag ctgagcttgt ctgatttata acctcaatca gtctcccaga
      541 ctgattgagc gaactcaagt tatgcctgcg actcgttgcc tatcatattt tcattttaag
      601 atgataggct aaaatggtct tccagaccat tttactacta aaagcaaacg aaatgactat
      661 actcaaataa attctattga aagtcatagt aaatagaatt ttgaggggta taaataaacg
      721 aatagatggg agacttacca tgagtgataa ctctaaaaca cgtgttgttg tggggatgag
      781 tggtggtgtt gattcgtcgg tgacggctct tttgctcaag gagcagggct acgatgtgat
      841 cggtatcttc atgaagaact gggatgacac agatgaaaac ggcgtttgca cggcgaccga
      901 agattacaag gatgtgattg cggtggcaga ccagattagc attccctact actctgtcaa
      961 ttttgaaaaa gagtactggg accgcgtttt tgagtatttc ctagcggaat accgtgcagg
     1021 gcgcacgcca aatccggacg ttatgtgcaa caaggaaatc aagttcaagg cctttttgga
     1081 ctatgccatg accttggggg cagactatgt agcgactggg cattatgctc gagtggcgcg
     1141 tgatgaggac ggcactgttc acatgcttcg tggcgtggac aatggcaagg accagaccta
     1201 tttcctcaac caactttcgc aagaacaact ccaaaaaacc atgttccctt tgggacattt
     1261 ggaaaagcct gaagtacgca gactagcaga agaagcaggc ctggcgactg ctaagaagaa
     1321 agattcgaca gggatttgtt ttatcggaga aaagaacttt aaaaacttcc tcagcaacta
     1381 cctgccagct cagcctggtc gcatgatgac tgtggctggt cgcgatatgg gcgagcatgc
     1441 aggtcttatg tactatacaa tcggtcagcg tggcggactc ggtatcggtg ggcagcacgg
     1501 cggtgacaat gccccttggt tcgttgtcgg aaaagatcta agcaagaata ttctctatgt
     1561 aggacaagga ttctaccatg attcgctcat gtcaactagc ctagaagcca gtcaagtcca
     1621 ttttatgcgt gaaatgccag aagagtttac gctagaatgt acggctaaat tccgttaccg
     1681 tcagcctgat tctaaggtga cagtacatgt caaaggagaa aaggcagagg tcatctttgc
     1741 ggaaccacaa cgcgcgatta caccaggaca ggcagttgtc ttttacgatg gcgaagagtg
     1801 tctaggtggc ggtttgattg acaatgctta ccgcgatgga caagtttgtc agtacattta
     1861 gattgacaaa ttttctcaat ttgctacaat aataacagca atagaaatga tggtcaaagc
     1921 tcatggatgt tgcaggcttt tttgtcctgc acttctttgt agttttgact gtttttgtgt
     1981 cgtttaaggg aaaggataaa aatgactcaa caagactttc ggacaaaagt agaaaatacg
     2041 gtttttggtg ttcgggcgac agccttgatt gtccaaaatc acaagcttct agttaccaaa
     2101 gacaagggca agtattacac tattggcggt gcgattcaag tcaatgaaag cacggaaggc
     2161 gcggtagtcc gtgaagttag ggaagaactg ggtgtcaaag ctcaagctgg ccagctagct
     2221 tttgtagttg aaaatcattt tgaacaagac ggtgtctatt atcacaatat cgagtttcat
     2281 tatctggtag acttacttga agatgcccca ttgaccatgc aggaagatga gaaaaggcag
     2341 ccctgtgagt ggattgactt ggataagctt gaggatatcc agctagttcc agccttttta
     2401 aaaacaaccc tacccgattg ggacggccaa ctaaaacaca ttcatcgtga ggaataggag
     2461 agaaacatga cttatcattt tactgaagaa tacgatatta ttgtaattgg tgcgggacac
     2521 gctggggttg aggcttcctt agctgctagc cgtatgggct gcaaggtctt gcttgcgacc
     2581 atcaatattg aaatgctggc tttcatgcct tgtaatccct ctatcggtgg ttctgctaag
     2641 gggattgtcg tacgtgaagt cgatgccctc ggtggcgaga tggccaagac cattgacaag
     2701 acttacatcc agatgaagat gctcaacaca gggaagggac cagccgttcg tgcccttcgt
     2761 gcgcaggctg ataaggaact ttactctaag gaaatgcgca agacagttga aaatcaagaa
     2821 aatctgaccc ttcgtcaaac catgattgat gagattttgg tggaagatgg caaggttgtc
     2881 ggtgtgcgta cagccaccca tcaagaatat gctgctaagg ctgttattgt gacgacaggg
     2941 actgctctcc gtggggaaat tatcatcgga gacctcaagt actcatcagg tcctaaccac
     3001 agcttggctt ctattaacct agctgacaat ctcaaggaac tgggtctcga aatcggtcgt
     3061 ttcaagacag gaacccctcc acgtgtcaag gcctcttcta tcaactacga cgtgacagaa
     3121 atccaaccag gagatgaagc gcctaatcac ttctcataca cttcacgtga tgaggattat
     3181 gtcaaggacc aagtgccatg ctggttgacc tataccaatg gtaccagtca tgagattatc
     3241 caaaacaacc tccaccgtgc gcctatgttt acaggtgtgg tcaagggagt gggacctcgt
     3301 tactgtccgt cgattgaaga caagattgtg cgctttgcgg acaaggaacg tcaccaactc
     3361 ttccttgagc cagaaggacg taatacagag gaagtctatg tgcaaggact ttcaaccagt
     3421 ctgcctgagg atgtccagcg tgacttggtt cattccatca aaggtttgga aaatgcagag
     3481 atgatgcgga caggttatgc tattgagtat gatatggtct tacctcatca gttgcgtgcg
     3541 actttggaaa ccaagaaaat ctcaggtctc ttcactgctg gtcagacaaa tggaacgtca
     3601 ggttacgaag aggcagcagg ccaagggatt atcgcgggta tcaatgcggc tctgaaaatc
     3661 caaggcaagc ctgagttgat tttgaagcgc agtgatggtt atataggggt gatgattgat
     3721 gacttggtga ccaagggaac cattgaaccc taccgtctct tgaccagtcg tgctgaatac
     3781 cgtctcattc ttcgtcatga caatgctgat atgcgcttga ctgagattgg ccgcgagatt
     3841 ggccttgtag acgatgaacg ctgggctcgt tttgaaatca agaaaaatca atttgataat
     3901 gagatgaaac gcctagacag tatcaaactc aagccagtca aggaaaccaa tgccaaggtt
     3961 gaagcgatgg gattcaaacc gttgacagat gcagtgacag ccaaggaatt ccttcgccgt
     4021 ccagaagttt cttaccaaga tgtggtagcc ttcatcggac cagctgcaga ggatttggat
     4081 gataagatta tcgaattgat tgaaacagaa atcaagtacg aaggctatat ttcaaaagcc
     4141 atggatcagg tagccaagat gaaacgtatg gaagagaaac gcattccagt caatatcgac
     4201 tgggatgaca ttgactctat cgcaaccgaa gcccgtcaga agttcaaact catcaatcca
     4261 gaaaccatcg gccaagccag ccgtatttcg ggagtaaacc cagcagatat ttctattttg
     4321 atggtgtatc tggaaggtaa aaatcgtagt atttctaaaa ctcttcaaaa atcaaaatga
     4381 tacgtcgtcg gcttcttacg aatgagttca aagcttggct ttgattcatc tccagcctcc
     4441 catagttccc cgaactatgg gagctaactc aagttatgct ttcgcttagc cttctagtct
     4501 gatttcgatt tttattgata ctcttcgaaa atctcttcaa accgcgtcaa cgtcgccttg
     4561 ccgtaggtat ggctactgac ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag
     4621 caacctacgg ctagcttcct agtttgctct ttgattttca ttgagtatga gttttaatct
     4681 caaaagaaag catagagaaa aacagctccg aggacggggc tgttttcttg ctttattctt
     4741 catctggtgt gaggatcatc gggatgatga tcggttcacg ttcggtattt tcatagagga
     4801 aggggcgaat agcgttgaca atggcaccat tgacagattg cacgctagca tccttatttt
     4861 tcagtgcgat acgaatggca ttgaagagga tacgctggct ttggcgaatc aagtcgccag
     4921 actctctcat gtagacaaag cctcggctga ggatgtctgg accagataga atcatctgcg
     4981 atttgaagtc aacagttgcg actgccagaa cgacaccgtc ttcagataga tcgcgacgat
     5041 ctttgaggac agctgcgcca atttcaccga tacgatttcc atcgacatag atatcttggg
     5101 cgttgaaatg acctgcgata cgagctgagt cagcagtaag ggcaagcaca tcgccattgc
     5161 tcatgataaa gatattgtcc ttctcaacac cagtatccac tgctagtcca gcgtggactt
     5221 tttgcatgcg gtattcaccg tggacaggca tgaagtattt tggcttaatc aagcagagca
     5281 tgagtttttg ctcttgctga ccaccgtgtc cagatgtatg gatattgttc actttaccgt
     5341 ggataacttc gacaccagct tcagaaatga tgttaatcag cttgttgacg ctagtagtgt
     5401 ttccagggat gggactagaa gagaagataa cggtatcacc tggttgtaat tgtacttgac
     5461 ggtgggttcc gttggcgata cgagagaggg ctgccatagg ctcaccctga ctacctgtac
     5521 agaggataag aacttctcct gcaggataat ctttgatttc atttggctcg ataaaggttc
     5581 ccttaggagt tttgatgtag ccaagatcga ttccgttgac aatggccttt tccatagaac
     5641 gaccaaagac cgcaatcttg cgtccagtct taacagcagc ttctgttgcc tgctggagac
     5701 ggaagatatt tgaggcaaag gatgcaaaga tgatacgtcc ttcaatacct tggataatct
     5761 tcataatgga ctgaccaacg actttttcag agttggtaaa ggttggtact tccgcatttg
     5821 tcgagtcaga caggagacag agcacgcctt cttcaccaag cgcagccata cgatgcaagt
     5881 ccgcaggttc tccaactgga gtaaagtcga acttaaagtc acccgtacag acgattttcc
     5941 cttgaggagt atgaatgaca atccccaaag gctctggaat agagtgagtc gttctaaaga
     6001 aagttgcctt gagattttta aaggtcaact cggtgttgtg gttgatttcg taaagtttgg
     6061 cgttgcgcaa gaggccgtgt tcttcgagtt tcccacggat caaagccaag gcaagcggtc
     6121 cagcataaat agggacattt gcttgcttga gtaggaacgg aatcccacca atgtggtcct
     6181 cgtgtccgtg tgtgattaaa acagccttga cgcggtcgat attgtctacg atgtaagagt
     6241 agtcaggaat gacatagtcg ataccaagca agtcatcttc tgggaattta atcccagcat
     6301 cgacgatgat aatctcgtct tggtattcaa ttccgtaagt gtttttcccg atttctccta
     6361 gaccaccgat ggcaaaaacg ccgacttctt caggtttaag agtgtaggcc atattagaac
     6421 tccgtaattt cgaaggcgcc agtttctttt tcgtaatcga gcaatttgtc agacaagagt
     6481 tcgatatatt cgatattgta ctctgggcga ttttcttcga caagttggcg agcagtgata
     6541 cggccctcaa gttctgagct ggtatcgatg tctaggtaaa gcgcgcgtgt tgtttcacgg
     6601 cgtgggctac gttcttttgt ttcttgataa aaaactttgt aaatcatata gttcctttct
     6661 atttacaggt cagcttattc caaactttta gcagatattt gcttgatttc attccatttt
     6721 gtgtctagat tgaccttgat tcgttacaat tatttcaatt ataccacaaa atgaaaaatt
     6781 agtaaaagac ggaaacgaga aagttagggg acgatttctt tggtaagcgt ttgcaaaaat
     6841 aaagaaaatg tattatgttg ataacggaag tgaaatttat tgcttgtcat aattccatat
     6901 agattttaag tcaaggaggt tgccctatgt ataacttatt tgcttttgct atcggagttc
     6961 gtttgttagc ttttatcgtt tttgttgctt gcatttatgg aggaaatctt ctatttgcca
     7021 aactggaacg atgacaaacc aagttcttgt ggaaaattac ctttgtgact ctctactcgc
     7081 tttttctcct ccttgtaacc tatgtcgttt ggtttgtatt ttactttgga ttaaatgctt
     7141 agatgccctg ctcatgctag ggcatttttg tttggagata agaagacaat agatttacga
     7201 tacgaaaagt ccaccccatc tatccagatg aggcggtttt tgtatttttt agaaatgaca
     7261 tgataatggt attttcagag cttattagtt ttatggtaat cattcttctg ttcaaaaata
     7321 gagttgaagc ataaaaataa aacaatacaa acagataaat caattggtaa agggatagta
     7381 gtaatgttca aatcattgag aatgctgagc aaactgtaag agatgaagac aataaaattt
     7441 atacttataa aaatatgttt cttatctagc atgacttacc aaacttttta cgaaggtctt
     7501 ttccaatggt ataacctgcc ataaataaag cgataccaac acctacacca aagccaccct
     7561 tgatttcttg caattcctta ttagaaattt cacgatagtt gttcaaattt ttcatcatat
     7621 taatctcctc ctaaaaaata accagctgcc aaaccagaac ctataagtgc tgttccacct
     7681 gcaatagcct tccaagatac tgctactcca aagataacca agggagcgag accgccatca
     7741 atatctgata attcattttc atataaggat aaaaattgat tgtcaagaat gtcaaaattt
     7801 gtcattgaac tttcctcctt ttttcttgtt cacttttata ttcggaaaag aaaaggaaaa
     7861 gtgagcattt ttttaaatta tttttagtta agtgagggca ctcttgtctg ggggcaaaga
     7921 aaattcccat gtgccatctt ttgtagtata atagtaagca gacaaaaaga taggaatgtg
     7981 ttatgaaagt attagctttt gatacgtcca gcaaggctct ttctctcgct attttagagg
     8041 ataagcaggt tcttgccgag acgacgatta atattaagaa aaatcacagt attaccctta
     8101 tgcctgccat cgattttttg atggcaagtt tggattggac acccaaggac ttggaccgaa
     8161 tcgtggtagc tgaagggccg ggtagctata caggcttgcg aattgcggta gcaactgcca
     8221 agaccttagc tcataccctg aacatcgagt tggttggtat gtcgagtctc ttggctctgg
     8281 tgccccacca acaagaaggt ttgtttgtcc ccttgatgga tgcgcgtcgc aataatgttt
     8341 atgcaggatt ttatgaaaat gccaaacctg tcatggcaga agcacatctg ccttttgagc
     8401 gagtcattga gctaatcaag ggcgctagtc aggtaacctt tgtcggagaa gttgtcccct
     8461 ttgttgagca gattcaaaaa cacttgccaa gggctgatta caaagaaaca ttgcccaatg
     8521 cagctagtct agctcttttg gcctgggaca aggaaacaga ctccttgcat gattttgtgc
     8581 caaattacct caaacgtgtt gaggcagagg aaaactggct caagaaccat accgagtctg
     8641 gtgagtccta cattaaacgc ctatgataga aatcaaacga atccaacagc aacctgcctt
     8701 ggctcaagct atctacgctg tcatggcagc tgtttaccca gtcagtcctt ggacactaga
     8761 acaaatccaa gcagatctgt cccaagacca gacttggtat gctctggctt atgatggggc
     8821 agaagtgatt ggctttctag ctgttcagga gactctcttt gaagcagaag tcctgcaaat
     8881 cgctgtcaaa ggagcttatc agggtcaggg aattgcgtca gccttgtttg ctcaattgcc
     8941 gacagataag gagattttcc tcgaagtcag aaagtcaaat caacgagcgc aagcatttta
     9001 caagaaagaa aaaatggcgg tcatcgctga gcgaaaggcc tactaccatg acccagtcga
     9061 ggacgccatt atcatgaaga gagaaataga tgaaggatag atatatttta gcatttgaga
     9121 catcctgtga tgagaccagt gtcgccgtct tgaaaaacga cgatgagctc ttgtccaatg
     9181 tcattgctag tcaaattgag agtcacaaac gttttggtgg cgtagtgccc gaagtagcca
     9241 gtcgtcacca tgtcgaggtc attacagcct gtatcgagga ggcattggca gaagcaggga
     9301 ttaccgaaga ggacgtgaca gctgttgcgg ttacctacgg accaggcttg gtcggagcct
     9361 tgctagttgg tttgtcagct gccaaggcct ttgcttgggc tcacggactt ccactgattc
     9421 ctgttaatca catggctggg cacctcatgg cagctcagag tgtggagcct ttggagtttc
     9481 ccttgctagc tcttttagtc agtggtgggc acacagagtt ggtctatgtt tctgaggctg
     9541 gcgattacaa gattgttggg gagacacgag acgatgcagt tggggaggct tatgacaagg
     9601 tcggtcgtgt catgggcttg acctatcctg caggtcgtga gattgacgag ctggctcatc
     9661 aggggcagga tatttatgat ttcccccgtg ccatgattaa ggaagataat ctggagttct
     9721 ccttctcagg tttgaaatct gcctttatca atcttcatca caatgccgag caaaagggag
     9781 aaagcctgtc tacagaagat ttgtgtgctt ccttccaagc agcagttatg gacattctca
     9841 tggcaaaaac caagaaggct ttggagaaat atcctgttaa aaccctagtt gtggcaggtg
     9901 gtgtggcagc caataaaggt ctcagagaac gcctagcagc cgaaatcaca gatgtcaagg
     9961 ttatcatccc ccctctgcga ctctgcggag acaatgcagg tatgattgct tatgccagcg
    10021 tcagcgagtg gaacaaagaa aacttcgcag gctgggacct aaatgccaaa ccaagtcttg
    10081 cctttgatac catggaataa agagtggctc tttgtcaagt gtagtgggta ggcgaaaagc
    10141 tacaatctgg agagtacgaa attcgtactc tcttttttga tgttcaaagt catcaaaatc
    10201 cgttttttaa aattgttaaa gttccggaaa ccaaaggctt tgcgcttgat aaccttaatc
    10261 aaattattgg tcgcttcaag tttagcgttg gaataaggca gcttaagtgc gttgataatc
    10321 ttatctctat cccttaaaaa agtccaaaag accgtttgaa aaagcggatg aaccgttggc
    10381 agttcttgct caatcaatcc aaagaaatgg tcggcattct tctcttgaaa atgaaagagc
    10441 aggagttgat agagttcgta gtgaacctgt aatccctcag agtaagaaag cagcttatct
    10501 cgtacttccc gatgggttaa gtgcattcga aacgtgggct gatagaatcg tttctgacag
    10561 agcttgaagc tatcctggtg tagtaaatca gtccagtgga ctgatttagc ccgagcctag
    10621 aaacgaaaaa gcgagggttc caaaagcgct tgagcgctcg atactccaag gattttcggt
    10681 caaattggtt catgatttgg attcgtactc ggttcatagc tcggctcaga tgttggacaa
    10741 tgtggaagcg gtcaagaaca atcttcgcct ttggaaagag ttgcttagcg agccgataat
    10801 aagggctgta catgtccatg gtgatgacct cgaccagctc ccgaacctct ctctgatagc
    10861 gttggaaatg gtttcgaatc accgcatgag ttcgcccgtc taaaattgcg aggatggatt
    10921 tggactcaaa atcttgggca atgaagctca ttttgctctt tttgaagcta tactcatccc
    10981 aactcataac ttttggcaac ttggtccaat cggtttcaaa cttaaattcc ctcagttttc
    11041 ggatgacggt ggaagttgag accgccaatc tgtgggcaat ctcagtcata gactgctttt
    11101 caaggaggag ctgagcgatt ttttgtctca ccatgttgga aatctggcaa tttttcttga
    11161 caatggatgt ttgagaaacg accaccttaa ggcaattctt gcactgaaag cggcgctttt
    11221 tgagatgcag taccgtgggt aaaccctgac agtcgagaag cggaatttta gaggctttct
    11281 ggaagtcgta tttgatcatc ttcccttgac aatgaggaca aggaggagcg ggggaatcca
    11341 actttgcctg aacgactaga tgggtttggt atttcagaac agacaagatt ttgatatttt
    11401 tgtcttccaa tccgagcaaa tctgtggtat tcttaagttg ttccatatga accctttcta
    11461 atgagttggt tagacgcttt tcattatagg tcatatgggg ctttttttct acaagaaacg
    11521 accctataat tcctggggtg ggattaccca ctacagaaat tatagagcca aaacattcca
    11581 aagtcttgtc tgactctgga atgttttctg ttcacagttg ttttgtaact gcctaataag
    11641 taaccgcgct ataacgaggt atctaccgag attgtcaatt ctccagtata ctgttataaa
    11701 aaacaaaact ggaggatttt tttatgtccc cccatcgtcc catcgactgt tccgtagctg
    11761 cccaataacg gagtatagtc ggctgaaaca agaataggac aaaagtgcct caagaaaagc
    11821 atcgtaattt gacaatatta ttctgagatg tttttgatgt aagcccatat tttctcaatg
    11881 ggattatact cgggtgaata ggtaggaagt ggtaacagtc tatgccctgc tccttacaca
    11941 tgttcattct gtgaaacctt gcattgtcca taatgataag ggatggtgta tctaaagtag
    12001 gtagtaagac tttttggaag caagcttcga aaaagtcact cgtcatcgta tctttatagg
    12061 tcatcggagc catagtatat tgaaacaaaa aagggcatta gtacttctat aacagtatcg
    12121 caatctctgg tgtgcgttgt ctcgatctta attcaaataa ttatatcttc ttccagagag
    12181 actaactgcc tgctcaaggc tcgatcatat tcgagataaa aataggtctc aacccctgtc
    12241 tcataaatat aaataggagt caggtagctt aagtgattca attctttaag gaaccgattt
    12301 actttttctg ggtcttgttc gcagtaggta cggctctttt ttagactata tcccatagcc
    12361 tttagagcgt aatgaatagt tgttggagga cagttgaatt cagcagctat ttcagtcaaa
    12421 taagcatcgg gatgagtttc aatatagatc tttaatttat ctctatcaac tttttcaatt
    12481 aatagtggaa gttttcttaa agttagtgta ttgaaacgtt tttatacagt gctaaaattt
    12541 gaagtgtagt gcagatgtat ttgtaatagt attatagcaa ttctttggag aaggtcgaga
    12601 caagagaaaa taggtatctt tgagatataa gcatgattta ctataaaatt attgagttat
    12661 tcataaaaat ttctctatca aatatcataa tgcgtcgttt aaggagatgg ttacaatgca
    12721 atatagttgt ggaaaaataa atattaatat ccctgatgga tatggagaca ttaaggatat
    12781 agtgttttcg gctcatatta tagttaggta taataatgga cattgtggag gtatagatcc
    12841 gcatataatt ggactttgta aaaagcagat cagaaggatg tctctatatc ctattttgat
    12901 aatcgtatct agagattcaa aggttattga tgattataaa aatttagata ttgcctatgt
    12961 tgattgtact caatgttcaa ataattttga aactgcctta cacgttaaaa atattttaaa
    13021 attattaaaa atccaactta tacactgtca tggctactca actaattatt ttttatatat
    13081 gttaaaaaaa cttgacaaga atggatttgg aaaggttaag acagtgataa catgccatgg
    13141 atgggttgaa tataacttaa aaaagaaatt cttgacttat tttgattttt ggacatattc
    13201 tatgggagat gcttttattt gtgtatctga aactatgaaa aaaagattgg agagtataat
    13261 aaaaaataag aagatagttg caataaataa cggaattaat gtatcaaata gcgatttaga
    13321 tgtagtaggt gttcaagact ttaaaaaaga attttgtatt ccaaataaca aaaaaatcat
    13381 ttgttatgtt ggaaggttgg atccagaaaa aaggccggat agattccttg aatttgcaga
    13441 aaaattattt ttagtcagag aagatgtgat ttttattatg gctggaaatg gtagtatgtg
    13501 ggctgctttg aaagaaaaaa tttgccattt gaaatgtaga gataatttca ggttacttgg
    13561 tgaaatctat ccagctacta tagtttacca aatatcggat ttattgtata ttccttctga
    13621 tacagaagga atacctatgt gtgttttaga gtcaatgtca caaggaactc cggttttagc
    13681 tagtaatgtt ggcgggttaa gtgaaattat tgaacatagg gttgatggat ttttatttga
    13741 gaaggaagat gttgagggag tgtgtgcttg tgctaatttt ttactcaatg attctgagta
    13801 tttgaaatat ataggtgaga atagtaaatc aaaaataaga aaacattttt ctgtgcaaaa
    13861 aatgtttgta gaaaccatga gagtatatga tgaattatta gagaagagta gtcatggata
    13921 ggaatataga tcaagaatta gtaagtatta taataccaac acataatagg tatgaatctc
    13981 tgattagagc tgtgaaaagt tgtttacatc aaagttataa aaatatcgaa gttataatta
    14041 ttgatgataa ttatagtaat gtaaatttaa gaaataaaat tatccatcaa tttggctata
    14101 ccaatcatag aattaagtta attttaagta atgaagattt aggtgcaact aatgccagaa
    14161 acataggtat caaaaattct agaggtaaat atatatcatt tttagacgat gatgatgaat
    14221 atatgccaga tcgaatttta aagttgatgg cttgttttaa aaagagtaga atgaagaatt
    14281 tagctttagt ttatagttat ggaataataa tttatccaaa tggtacacga gaagaggaga
    14341 agaccgattt tgttggaaat cccttgtttg ttcaaatggt tcacaatata gcaggtacgt
    14401 cattttggtt gtgtaaaaaa gaggtgctag aattaattaa tggttttgag aaaatagatt
    14461 cacatcagga cggtgttgtt ttattaaaac tacttgctca aggataccaa attgatatag
    14521 tgcgagaatt cttggtgaat tactacgctc acagtaaaga aaacggtatc actggagtga
    14581 cacaaaaaac aattaatgca gatgaagaat attataatta ctgtaggaaa tattttaatt
    14641 tattgagttt caacgagaga atattggtta caaagaaata ttattcttta aacataaagc
    14701 ggttactatt aataggagac aaatgcaagg ctttaaaagt aatcaagaag gcaagagaag
    14761 aaaaaatttt taacgaattt ctttttttga aatatatgtt attatatcat tttggttttt
    14821 tctattgtat atatgacaac tatgttcaat taaaatttag aaagtgagaa actattgtgt
    14881 atactattat aaaatcaaat ataaaaaaat ttagtttatt aacgatattt attgttgctg
    14941 gtcaattatt gctaatttat gcagcaacta ttaatgctct ggtgttgaat gaattaattg
    15001 cgatgaattt agagcggttt ttgaaattgt caatctacca aatgattgtc tggtgtggga
    15061 taatattcct tgactgggta gtgaaaaatt atcaggttga agtgatccaa gagtttaatc
    15121 tagagattcg aaatagagtt gccacagaca tctctaactc tacctatcaa gaatttcata
    15181 gtaaatcatc aggaacatat ctttcgtggc taaataatga tgttcagact ttaaatgatc
    15241 aggcttttaa acaacttttt ttagtaataa aaggaatttc tggtactata tttgcagttg
    15301 tgactcttaa tcactatcat tggtcattga ctgtagccac cttgttttca ttaatgatta
    15361 tgctacttgt accaaaaatc tttgcatcga aaatgcgaga agttagtcta aatttaacta
    15421 accaaaatga agctttttta aaatctagtg agactatatt gaatggattt gatgtgttag
    15481 cgtccttgaa tcttttatat gtattgccta agaaaattaa agaagcagga attttattaa
    15541 agatggttat acaaagaaag acaactgtag aaacgttagc aggcgctatt agcttctttc
    15601 tcaatatttt ttttcagata tctctcgttt ttttaacagg ctatcttgca ataaaaggaa
    15661 tagtgaaaat tggtactatt gaagcaatag gagcactaac aggtgttatt tttacagcgc
    15721 taggtgaatt aggaggtcaa ttatcctcta ttattggtac gaagcctatt tttttaaaat
    15781 tgtattcaat taatccaatt gagtcaaata aaatgaatga tatcgaacca aatgaggtga
    15841 atagagattt tccgttatat gaagcaaaaa atatttgcta taagtatgga gataaagaaa
    15901 tattaaaaaa cttaaatttt tgttttcaac gtaatgaaaa gtatttaatt ttaggtgaaa
    15961 gtggaagcgg gaaatctaca ttattaaaat tattgaatgg ctttttgaga gattatagtg
    16021 gagaattgcg attctgcggg gatgatataa aaaaaacctc ctatttaaat atggtttcga
    16081 atgttctata tgtagatcaa aaagcttatt tgtttgaagg tacgattaga gataatattt
    16141 tattggaaga aaattatact gatgaagaaa tactacagtc tttagagcaa gttggtttga
    16201 gtgtaaaaga ttttcctaat aacattttag attattatgt tggtgatgat gggagattac
    16261 tgtcaggagg gcagaaaaaa aaaattactt tagctagagg gctaattaga aataagaaaa
    16321 tagtattaat tgacgaggga acttctgcta tcgataggag aacttcgtta gcgattgaac
    16381 gtaagatatt agatagagag gatttgactg tcattattgt tacccatgct ccgcatccgg
    16441 aacttaaaca atattttact aagatatatc aatttccaaa ggattttatt taagaatata
    16501 ggggagggaa atatgagatt ctattgtgaa gcttatgagg taattactga agagaaaaaa
    16561 gtatacttta atgatattga gttagaagtt aagtattcct ctgtcgaaga attgtttata
    16621 atatgtgaga aattattaga taagaaaaaa gtatcatttt tttatgtaga tgagaaaccc
    16681 ttaaggtatc tgttatttga ctatatattt ctactagttc tagctaaaaa aaaatatccc
    16741 aatcttagat ggagtttcca ataagcaagt tgatccaacg ttgctgcatc acttttcttt
    16801 ggaaattgaa aagaatttta tcgatttttg ctataaaaat atggatctca tcctaaaaac
    16861 tcaaagtata tctttgtgtc atagagaaga gcttattatt gtagatgttt cagatgactc
    16921 taaatttggt gttttttaca agcgttttag aacactggtt gataaaaata acggaaaata
    16981 tgtttgtgtt tataatttca gtcgtgtttc agatatactg caaaactgga aaaattattg
    17041 caatcgaaaa ttttcggtta cgtttactga aagccaattt gaattattta agcttttata
    17101 taatcaaaaa aattttaaaa caatttcgtt gctatttgga aaaaaattgt tgctggagga
    17161 attatctatt atagcgatct tactaatata gaatactttt gtattttttg gtgggatagt
    17221 atgtttggga aagattctat tggaaaatac gtatatgtag aagagattag tagatgtcat
    17281 tttttagata gaaattattc tttttgttat ggtttacaag attataaaag taaacttatt
    17341 aaatattttt tagaatagtt aatctattcg agagagataa agaaatatgg aaaatacttt
    17401 attgaatatc acaggaagct tcgatatgga aactaggaat ctaattagtt attctttaac
    17461 tgatatcttt gaaacagata aaataagaat tgaacttctt ggagaaattt attataaaaa
    17521 tataaagttg gaattgcatg aattcgctgg attgtataag atttatggaa ttagcttaat
    17581 aaagaatatt accggaatgt ttttaattat aatttttgat acgaagacaa aagaattaaa
    17641 aatttttcaa gatataacga cttcatactt taatttatac tatactgttt atggaggtgt
    17701 gttctattat agtacatctt taaagaaagt gatgaagtta tctcatgttc ccgttacctt
    17761 aaataacaaa aaaatacaag aatttataag aaatggattt attttagatt caaatacttt
    17821 agtaaccgaa attaataaat tagaatattt ctcttacatt tctgtaaata atactcttcg
    17881 tatatgtggt attgattata atgattcaaa caattttact aaagaacaag tattaaagaa
    17941 ttgggactct atgctacgtg aatctatatt aagagtgtat agtgaagcag gagaggctaa
    18001 tattacacta tcatctggtt ttgattcaaa ttatatatta tatacattag cgaattatac
    18061 gaattcttca attaatgcat tttgcatagg aggagaaaaa ggaattaatg agattcctga
    18121 agtaactaaa attgcaaaat tttatggtat aaatttatta gttgatactg taatgagcca
    18181 agatttagaa tattttcccg atatagtatg gagattggaa ggaagtctct ttgaatgtgg
    18241 tgtcatactg cagtactatt taggcaggtt gttgttccaa aaagggaaca caagtattct
    18301 ttgtggcgag tcagcggatg aaataatgac ttttaagtat cattctgtga actacaatca
    18361 attttgtaat gataaacaga agtcagtata ttttagttat tccgactatc cattttatgt
    18421 tacaaattca attattttaa agaaaaatag cctacttttg catagttttg gcattcatcc
    18481 tagatatcca tataaaatgt ctgagattgt tgaaatgtct aaaaaaatat cagatctaaa
    18541 cgataaaaaa gaatttcaca aaaagaactg tgagttgagg tttcaagata gtgttcttga
    18601 taacataaat agtgtcccgg gtacaactca tttatttagt tgtttaaata ttcaaacatt
    18661 agtaaaaatt attttatata tttttcgata caacagttgt atgaaaatat ttaattttag
    18721 agataaagag cttatctttt ttaataagat tgtaaatggg ctgatacaaa atattgagga
    18781 gaatttagag gatgatattg aaaggatatt gaaatattta tatatatgtt tatttaacga
    18841 aatattcatt attaagaata aggtgaattt ttttgatgat gtggaattta atcagacact
    18901 tagtgagttt ttagataaat tgtagaggga atggttatga gtaacaatac taagtatatc
    18961 tttttatctc cacatttaga tgacgcaatt ttttcctgtg gtgattatat ttcaaaatta
    19021 acttcagaag gagaaattgt acttgttatt actatatttt ctggttaccc tttgagccaa
    19081 cagctacagc cctctgctaa gcaatttcat aagttgtgta accttgggaa atatccgatt
    19141 gaagaaagga agaaagaaga caggttagct tgtgaacgtc tacaatgtga ttttagacac
    19201 ttatcgtact atgaatgtct ctataggaaa gatagaaatg gcaattttct ataccgtcat
    19261 atctatagtg aattaaaaaa tgaggacaca ttaaagaatg atatcataaa agagctgtta
    19321 atgcatttag acgacaaatg tgtcgtatat tgtccgcttt cacttggtga ccatgttgat
    19381 catgtttttg tgaatagtat tggaagggcg cttgaattta tgcgttataa agtaatatat
    19441 tatgaggact tcccatatgt aagtgatagt agtatggtta gttatatggg aaaaactaaa
    19501 gaattaaaaa tgtatcaaga ggaacttgat aaaaaacatt atattgatag aatatcatca
    19561 atattgtgct ataaatctca gattttgata atctggaaat cagttgaaaa acttttaaac
    19621 aatattaaag agttgtattt aaggaatggg gcagcttatt ctattagatt ttggattaag
    19681 aaataaggaa gtagttttat gaatatagca gtaattggtt tggggcatgt tgggctggcc
    19741 tacgcgttac tatttgcatc taaatataaa gttgttgcat atgatataga ttctgtaaaa
    19801 ataaataatt taaaaaaggg cattcttcca tctaaaaatg aagagcttat gaagtttttt
    19861 tgcgagaata acttaaatat tacttttttt gatacatttt ctgaaattaa aaataatatt
    19921 gattattata ttattgcgct tccgacagat tatgatgaga aaattggtag ttttaataca
    19981 tatgaaatcg aacaaacggt atcgaagatt ctgagggtaa aacctaatgg aaagattatt
    20041 ttaaagtcaa cagttccgat cggcttttca aacaaattaa aaaggctgtt tgatacaaaa
    20101 aatatcattt ttgtccctga atttttgaga gaaggttgtt ctatatatga taatttatat
    20161 ccaagtcgca tagttgttgg agatgagaca gttgaaggaa gaaaaattgc agagttgttc
    20221 ctttcgatta gtactcatag tactgccaat attaaaaatg ttatgttagt ttcttctact
    20281 gaagcagaag caattaagct tttttctaac acattcttag ctctccgtgt tgcttttttt
    20341 aatgaactag attcttttgc tgagaggaga agtttaaatg ctgaagttgt aataaaaggt
    20401 gtttgtttag atccaagaat tggaaatttt tataataatc cttcttttgg atttggagga
    20461 tattgtcttc ccaaagatac taaacaatta aaaaaagaat ttatagaaat aaatgcccca
    20521 gtgatagaag cgattgatat ttcaaacaca aatagaaaac agttcatagt taaacaaata
    20581 ttggaacgaa agccaaagat agtaggaata tataaattgg ggatgaaata taattcagat
    20641 aattacaaag agtcagctat tttaagtata attaatgaac tattgattgt cggtataaaa
    20701 attttagtat atgaaccaaa tttaaacgtt agtatagata acgtaatttt tgaaaagaat
    20761 tttgaactat ttacaaaaca aagtgatcta attgttgcaa atagatggga taggggcctt
    20821 gaagcttata aagataaagt ttacacaagg gggatctgga taagagatta actattgata
    20881 ttaaaaaggc aataatttat aaaatttgta caaaaaaatg ttaaattttc acattttcat
    20941 agtatactgt ttaatagaaa gtaggttctt tgtaaccgct ccattataaa atcctttcac
    21001 tcttccggta tactattagg aaaaacataa ctggaggata ttttgagctc acacctcatc
    21061 gttccagtgg ctgttcccca agctcgtgta ctgcccaaaa aagttagaca ttctatttag
    21121 aacgaggatt gagttctgta ttgtacaagg ctcggtcctt ttagagtcag cttaaggctg
    21181 gcttttttat tttttctaac tatcagaata ttttgacaaa tgaacacaaa taatgatata
    21241 atatgcaaaa gctaggaggt ggtaggatga ttgaaaaaat ggaattgggg gaattttaca
    21301 aggaattacg tttggcgaga aagctcaagc agtcagatgt ggcttgtgac gggctaacag
    21361 cttctcagtt gtccaagttt gagctagggc agtccatgtt gtctgctgat aagctcatat
    21421 tagccatcca agggatcaat gtgacctttg atgagtttgg gcacaagctc aacaactatc
    21481 aagaatctcc acatatgcag attggtagaa aggttgtgga tcgctttgct catcaagata
    21541 tagctggctt agagcaactg ttggaggaag tcgagcaaga acagatggca gagacttatc
    21601 gtcgtttgaa tgctattgta atcaaagatg ccatccactc actagataaa agctacccac
    21661 tagcagagga ggatagcgag tttttgacca cctatctcta tgctatcggg tcttggacct
    21721 ggtttgaact ctatctcttt tgcaatacta tgcccttctt gagcaatcaa gatctgatct
    21781 ttttatcaac ctccttactc gaaaaatcca aagaatttaa agagttagta cacaatcgat
    21841 tgtatatgaa gcaaggactc ttaaatatca tctcagagct catggagcgc aaactttttt
    21901 cttatatccc aatctttgaa gccgagctgg agagtatgct ccgtccatac gatgtttttg
    21961 agaaattatt gtggcagttt ttaaagaaga tgagcatttt ccttcaaact aagggaagca
    22021 atcaaaaaga gattgaacac tttatccaat ctctgcaagt attagaaaat ccacaattaa
    22081 tagccctttt tgaattgcgt ttgcagcaat acaaaaagct tatcgattag ttagaaatgg
    22141 caaaataata ataatctcag caacgatttt caataatgtt aaaatttgtt tcttcatatt
    22201 tctccactcc tcattagtag taactttatt ataccagaga agtaatcaaa ttcaccaaaa
    22261 tcgcaaatct gaaatttcta taagaaaaaa tatcaaatat gcgattttct aaaataagcc
    22321 aattttcgtg ttatactgta cttgtaaagc acttgaagca aatcctaggt cgcagaagtg
    22381 gtttacaaat gaagataatt gaaggagtgt aaaagatgtt aaatttacaa tttgcagaaa
    22441 caatggaatt gacagaagct gagttggaga cagtttatgg aggggaactt gggtataatg
    22501 ccgttatccc aggtggtagt tggggaggtt taggaacgtc ttggtcaatc actaatttct
    22561 ggaagaaata ttttaaccat gattcttcca ctgttaatcg tcgccattat tgatattcag
    22621 agtccttgcc tttttcttgg gtagggactg tctttatttc atagtatagg agaaaataga
    22681 atgaaaaaga taatctcaca ccgctacttt attatagttt ttctactagt tattgctgac
    22741 cagaagttca gtgttttagt tttacgcagc gaccttgttg ctgggctatc tgactttgcc
    22801 tattatctgt cggatatgat gttgaatttt cttgtggttt tatttgctct tattgctatg
    22861 atttggtcgg ggaaatggca gaaaatcaat agtagaaagt ttaaaggatc ctatcttttc
    22921 tattccttcc tagctctgct tgcttttgtt gcttggaatt ttgtcacctt ttttcttttc
    22981 ccacctactc gaaatgaaat ttcttatcaa catgctgctc ctacttttac aggagctacg
    23041 gcatttttga tgtatttttt ttatcctgtg attgcaggtc ccatttttga agacatgatt
    23101 tatcgtggat tagtgatgac tgctctggaa aaaggaaaga aatgggggct agatgtactt
    23161 ggttccgctg ttttatttgg ggtctcgcac attagtaatc acggttgggt cttgacagac
    23221 tttgtcttct atatgggtgg aggtcttata tttgcagtct tatttagaat gacaaagtca
    23281 atttattggc ctattggact gcatatagtc tacaatggca ttggtcagct tttgatgtta
    23341 ctgtaatttt ggttgttagt agtatcgcgg tctatccttg gggaaagctt cccatttgaa
    23401 tttaagaagg agttgtgatg aaagtatttc ttcaaaatag agattttaga caattaacca
    23461 tcaaccagtg gatttcaacg cttggggata cgatttttta tctggccttc ctgaattatg
    23521 tggcagatgc atcttttgcc cctttggcga ttttactcat cacgatttca gaaaccctgc
    23581 cccaagttct acaaatcttt ctgggagttt tggcggattt tcaacatcat cgtgtcttga
    23641 aatacacagt cattagtttt gcaaaatttt tgctttactc tatagtgtct ttatcacttt
    23701 cagggcagtc tttctccttg ttgctagtag catttatttg tctgattaac ctcttgtctg
    23761 acacattgag ttatttttca ggcgccatgc tcactccgat tttcattaga attattgggc
    23821 aagaccatct ggcagaagct attggcttta aacagtcaac tgttagttta gtgaaaacaa
    23881 tcagtaatat cctaggagga gtcttactag gcattctatc catccagttt atttccttac
    23941 tgaacgctct taccttttta atcgcatttt taggtatcct cttcataaaa actgacctct
    24001 tgaaagtaga aaaaacgatt agctatcaag aaggactctc tgtaaaatcc ttttgccagc
    24061 atttgctcca atcatcgaaa ttgatatgga atatgaataa ggtgctcttg gttttgttta
    24121 ttatctctac tagtcaagca gtgataaatg ttacggttcc tatttccact ctatttttaa
    24181 ggaaccagcc ctttttgaat ttacaaacag gtcaatctct tgccttgtta gccacactag
    24241 aattgtcagc tcttattttg ggaagtctga tgagtggcta tctgcaacat accatttcca
    24301 taaaaatagc cctgtatgct tcactcctac tccaattact actcctagtg ggctttgcga
    24361 cagctcattt tggcttgatt ctgatcttta gctttttgga tgcctttttc gcgggtattc
    24421 tctctcctag attgcaagaa ctcgtcttta aacaaatacc tgaggagtca atgggagcag
    24481 ttcaatcttc tatcggtgcc attacggttg ttttacctag cttatttaca atagctttgg
    24541 taaccattgc tactagcttt ggaactctgg cagttagctt tgttttatta ctatttcttc
    24601 tagttgcctt tgtcatgctt ctgaatattc gtgaaagtat ttagtggaga atttctataa
    24661 tatatgtttg agactggatt gccagtcttt ttatgatggt caaaatcaac agactttttt
    24721 ctcttttctg aatgtgttat agtagactga atctaaaata gtacgaaaca attgctaaaa
    24781 catttataga aattaatttt actttcccaa tcgatttgtt ctcatcttat ttcaatctgc
    24841 tatataatag tccatgctgt ggctggattc ttttcagcct acttgtactc ttcgaaactc
    24901 tcttcaaacc acgtcagctt cactttgccg taggtatggt tactgacttc gtcagttcta
    24961 tccacaacct caaaacagtg ttttgagctg acttcatcag ttctatctgc aacctcaaaa
    25021 cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
    25081 tattaagaca atatgaggag aaagatgaaa gaaaaaggat tttaggaggg ggcgcaggca
    25141 gccatgccaa cggctcttgg ctatgtcagt atcggcctgg cctgtggaat tatcggtgcg
    25201 ccctatgtga cacctgttga gatgggcttg atgagtctct ttgtttatgc tgggagtgcc
    25261 cagtttgcca tgttggcact gattgtggtt caagctcctg tggcagctat tgctatgacg
    25321 gtttttctaa tcaatttgcg tctctttttg ttgagcttac acgcatcgac ttatttccgt
    25381 cataccagtc tttggcacaa tatcggtatg tctagtatct tgacagatga gacctatggc
    25441 gttttgatgg gcgaattagc ccatacagat aaggtcaatc cgatgtggat gcacgggaac
    25501 aatctcaaca gctatgtggc ttggtttgtg ggaacagtgg tcggaacggc tctaggtgac
    25561 ctgttgccaa atccagaaat ctttggttta gattttgccc tggttgggat gtttatcggg
    25621 atttttgctt cgcaattcca gatgatgcaa agacggattt ctgtccgcaa tctgctcatt
    25681 atcttagcag ttgttgcggt gtccttcttt ttacttttga cagtggtgtc tcagtcacta
    25741 gctgttctgt ttgcgacgct acttggttgt agcatgggga tggttttaga tggtcagtaa
    25801 gtatctttta ttagcagtta ttttctctgg tcttgtggcc tggattcccc gtatgattcc
    25861 cttcatcttg gtcaagtata agggcctgcc tacgattgtt gagcgttttt tgaagttttt
    25921 gcctgtttcc attatctttg ccttgattct ttcaagagta gtgacaggta aggttgggaa
    25981 ccttcctcaa atcaaatgac tggacttctt agcagtcttt ccaacagctt gggtagcttt
    26041 tcgctaccgc aatctagtcg gtacggttct ctttggagta gtcttgattg ccgtcttgcg
    26101 tttggtcttt taaataagtc ataaagaaaa cttatcacag agatagatat catataatgg
    26161 cgtaattact ttttttctga taagattata aggtattcta ttttggagga aatgacatga
    26221 aaaaaatcgt taaatactca tctcttgcag cccttgctct tgttgctgca ggtgtgcttg
    26281 cggcttgctc aggtggtgct aagaaagaag gagaagcagc tagcaagaaa gaaatcatcg
    26341 ttgcaaccaa tggatcacca aagccattta tctatgaaga aaatggcgaa ttgactggtt
    26401 atgagattga agtcgttcgc gctatcttta aagattctga caaatatgat gtcaagtttg
    26461 aaaagacaga atggtcaggt gtctttgctg gtcttgatgc tgaccgttac aatatggctg
    26521 tcaacaatct tagctacact aaagaacgtg cggagaaata cctctatgcc gcaccaattg
    26581 cccaaaatcc taatgtcctt gtagtgaaga aagatgactc tagtatcaag tctctcgatg
    26641 atatcggtgg aaaatcgacg gaagtcgttc aagccactac atcagctaag cagttagaag
    26701 catacaacgc tgaacacacg gacaacccaa ctatccttaa ctatactaag gcagatttcc
    26761 aacaaatcat ggtacgtttg agcgatggac aatttgacta caagattttt gataaaatcg
    26821 gtgttgaaac agtgatcaag aaccaaggtt tggacaactt gaaagttatc gaacttccaa
    26881 gcgaccaaca accgtacgtt tacccacttc ttgctcaggg tcaagatgag ttgaaatcat
    26941 ttgtagacaa acgcattaaa gaactctaca aagacggaac gcttgaaaaa ttgtctaaac
    27001 aattcttcgg agacacttac ctaccggcag aagctgatat taaataattt cttgaaatca
    27061 tccattctga gtaagatggg tggtttctca gtttttaggg atatagtttt aaactatata
    27121 tctgactatc taataacaat ttgtgaaatc aaacaaattg tgagatacta gtacggtatt
    27181 atttttaagg agaaagaatc atgaaaatca aaaaatggct tggcctagca gcccttgcta
    27241 cagtcgcagg tttggctctt gcagcttgcg gaaactcaga aaagaaagca gacaatgcaa
    27301 caactatcaa aatcgcaact gttaaccgta gcggttctga agaaaaacgt tgggacaaaa
    27361 tccaagaatt ggttaaaaaa gacggaatta ccttggaatt tacagagttc acagactact
    27421 cacaaccaaa caaagcaact gctgatggcg aagtagattt gaacgctttc caacactata
    27481 acttcttgaa caactggaac aaagaaaacg gaaaagacct tgtagcgatt gcagatactt
    27541 acatctctcc aatccgcctt tactcaggtt tgaatggaag tgccaacaag tacactaaag
    27601 tagaagacat cccagcaaac ggagaaatcg ctgtaccgaa tgacgctaca aacgaaagcc
    27661 gtgcgcttta tttgcttcaa tcagctggct tgattaaatt ggatgtttct ggaactgctc
    27721 ttgcaacagt tgccaacatc aaagaaaatc caaagaactt gaaaatcact gaattggacg
    27781 ctagccaaac agctcgttca ttgtcatcag ttgacgctgc cgttgtaaac aataccttcg
    27841 ttacagaagc aaaattggac tacaagaaat cacttttcaa agaacaagct gatgaaaact
    27901 caaaacaatg gtacaacatc attgttgcaa aaaaagattg ggaaacatca cctaaggctg
    27961 atgctatcaa gaaagtaatc gcagcttacc acacagatga cgtgaaaaaa gttatcgaag
    28021 aatcatcaga tggtttggat caaccagttt ggtaataaga aacagggagg tgggagagag
    28081 aattccacct cttgcttttg tatagagcat ggagtgtaaa gaagactatt cgttcataga
    28141 aaggtagaga gaatatggtt tttcctagcg aacaagaaca gattgaaaaa tttgaaaagg
    28201 atcatgtagt ccaacattat tttgaggttt tgcgtacctt gatttctaag aaatcagtct
    28261 ttgcccagca ggttggactc aaggaagtcg caaattatct gggtgagatt ttcaagcgtg
    28321 ttggagctga agtggagatt gatgagagct atacagcgcc ctttgtcatg gcacatttca
    28381 agagttcgcg tccagatgcc aagaccttga ttttctataa ccactatgac actgtgccag
    28441 cggatgggga tcaggtctgg acagaggatc cttttacgct ttcggtccgc aatggcttca
    28501 tgtatgggcg tggggttgat gacgacaagg gtcatatcac agctcgcttg agtgctttga
    28561 gaaaatatat gcagcgccat gatgatttac ctgtcaatat cagctttatc atggagggag
    28621 cggaggaatc ggcttcaaca gacctagata agtatttgga aaagcatgca gacaaactcc
    28681 gtggggcgga tttgttggtc tgggaacaag ggaccaaaaa tgccttggaa caactggaaa
    28741 tttctggtgg caataagggg attgtgacct ttgatgccaa ggtaaaaagc gctgatgtgg
    28801 atatccactc gagttatggt ggcgttgtgg aatcagctcc ttggtatctc ctccaagcct
    28861 tacagtctct tcgtgctgcg gatggccgta tcttggttga aggcttgtac gaagaagtac
    28921 aagagcccaa tgaacgagaa atggccttgc tagaaactta tggtcaacga aacccagagg
    28981 aagttagtcg gatttatgga ttggagttgc ctctcttaca ggaggatcgg atggcctttc
    29041 taaaacgttt ctttttcgag ccagcgctta atatcgaagg aatccagtct ggttatcaag
    29101 gtcagggtgt taagactatt ttacctgcag aagccagtgc caagctagag gttcgtctgg
    29161 ttccgggcct agaaccgcat gatgttctgg aaaaaattcg gaaacagcta gacaaaaatg
    29221 gctttgataa ggtagaatta tactatacct tgggagagat gagctatcga agcgatatga
    29281 gcgcaccagc cattctcaat gtgatcgagt tagccaagaa attctatcca cagggcgttt
    29341 cagtcttgcc gacgacagcg gggacaggac ctatgcatac ggtctttgat gccctagagg
    29401 taccaatggt tgcattcggt ctaggaaatg ccaatagccg agaccacggt ggagatgaaa
    29461 atgtgcgaat cgctgattat tacacccata tcgaattagt agaggagctg attagaagct
    29521 atgagtagag atattatcaa gttagatcag atcgatgtga cttttcacca aaagaagaga
    29581 accatcacag cggttaagga tgtgaccatt cacatccaag aaggggatat ctacggaatc
    29641 gttggatatt ctggagcagg gaaatcaacc cttgtacggg tgattaatct cttgcaaaaa
    29701 ccatctgcag ggaaaattac cattgacgac gatgtgattt ttgatggtaa ggtcaccttg
    29761 acggcagagc agttgcgtcg taaacgtcaa gatatcggga tgattttcca gcattttaac
    29821 ctgatgagcc aaaagacagc agaggagaat gtagcctttg cccttaaaca ctctggactc
    29881 agcaaggaag aaaagaaggc taaagtagct aagttgttgg acttggttgg tttggcagat
    29941 cgtgctgaaa actacccttc acaactatct ggagggcaaa aacagcgtgt ggcaattgcg
    30001 cgtgccttgg ccaatgatcc aaaaatcttg atttcagacg agtcaacttc tgcccttgac
    30061 cctaagacaa ccaagcagat tttggccttg ttgcaagatt tgaaccaaaa attaggattg
    30121 acagttgtct tgattacgca tgaaatgcag attgtcaaag acattgccaa ccgtgtggcg
    30181 gttatgcagg atgggcattt gattgaagag ggaagtgtcc ttgaaatctt ctcaaaccct
    30241 aaacaacctt tgactcaaga ctttatctca acagccacag gtattgacga agccatggtc
    30301 aaaatcgaga agcaagaaat cgtggaacac ttgtctgaaa acagtctctt ggtgcaactc
    30361 aagtacgctg gagcttcaac agacgagcca cttttgaatg aattgtacaa gcattaccaa
    30421 gtaatggcta atattctcta tgggaatatc gaaattctcg atggtactcc tgttggagaa
    30481 ttggtggtgg tcttgtcagg tgaaaaagca gcgttggcag gtgcccaaga agccattcgt
    30541 caagcaggtg tacaactaaa agtattgaag ggagtacagt aagatggaat cattgattca
    30601 aacctattta ccaaatgtct ataaaatggg ttgggctggt caggcaggct ggggaacggc
    30661 tatctactta actctttata tgacagttct ttccttcatt atcggaggct tcttggggct
    30721 agtggcaggt ctctttctcg tcttgacagc gccaggtggt gtcttggaga ataaagtcgt
    30781 attctggatt ttagacaaaa ttacctcaat ttttcgtgcg gttcccttta tcatcctctt
    30841 ggcaatcttg tcaccacttt ctcacttgat tgttaaaaca agtatcgggc caaatgcagc
    30901 ccttgtccca ctttcttttg cagtctttgc cttctttgct cgtcaggtgc aggttgtctt
    30961 ggctgaattg gatggcggtg tcattgaggc ggctcaagcg agcggagcga ctttctggga
    31021 catcgtgggt gtttacctat cagaaggtct tccagatttg atccgtgtga cgactgtgac
    31081 cttgatttcc cttgttgggg aaacagctat ggccggtgcg gttggagctg gtggtatcgg
    31141 taacgtagcc atcgcttatg gatttaaccg ctacaatcac gatgtgacca tcttggcaac
    31201 catcattatc attttgatta tctttgcaat ccaattcttg ggagatttct tgactaagaa
    31261 attgagccat aaataaaaaa gagccgcgtg gctcttttta actgatcaga ttttctgtgc
    31321 aaatttttta ctcaaggctt gtccaatcaa ggcacccact agggctccga tgacaatact
    31381 tgcgataaat agaaggacag ttccagggtt tggagcgacc atgatgcggt cgatatattc
    31441 ttgggatttt cctcttgcca gaagagtagc catataggct ttgggcgcaa tccacataag
    31501 caagattggt cctgttgtac taaaggcgaa aataatgaaa gaaaggaagt tctttgtttt
    31561 gtccttgtat tttcctaaat gagctactcc atctgctagg aggccacaga taattccagg
    31621 aaggaaggaa ccagcaccgt gtttagttcc caagaaaaag agggcaatga caaggccgat
    31681 agtggtaatg gctccaaagc gcggaacttt tgcgactagg atcatataga cgctaccgcc
    31741 gacaagggca gtaaaggcag gcgcataaaa catgtttcca gtttggtcaa agagattgcc
    31801 caaaaggaca ccaatcccca tgcagaggaa gtaaaggact gcaaaaagca gtgtagttaa
    31861 gatagatttc ttcatgaatt gtctcctgat aattttttca caattctcat tttaccatgg
    31921 tttggtggga ttgtaaatgg atactagaag tttttgaaaa cgcttgaaat atgatataat
    31981 ggtttcatag ttatttttag gggaatatca tgggtagatt tttagacttt gtctttaatc
    32041 gtttcttttt agggatgatt gcgacagcct tcttttggct attaacttta gcaggaggga
    32101 ttatccttgg tctagcgcca gctagtgcca ccttgatgag cttatatgca gaacatggtt
    32161 atagctttcg ggaatacagt ttgaaggagg cttggtctct ttacaagcaa aattttgtct
    32221 caagcaacct gattttctat agctttttag gtgtgggtct agttttgacc tatggtttgt
    32281 atctcttggt gcaattgcct catcagacca ttgttcattt gattgcgacc cttttgaatg
    32341 tcctagtagt tgccctgatc tttttggctt atacagtatc tttaaaatta caagtttatt
    32401 ttgccttgtc ctatcgaaat agtctcaaat tatccttgat tggcatcttt atgagtctag
    32461 cagctgtggc caaggttctc cttgggactg tgctacttgt agtaattggt tactatatgc
    32521 ctgccctgct attttttgta ggaattggga tgtggcattt ctttatcagt gatatgttgg
    32581 aacctgtcta tgaaatcatc catgaaaaat tggcgacaaa atagaatgaa gcagttttgg
    32641 ctacatacgc ttctaagaac ctacagttca gtgatgatca ttattattgc gagttttgca
    32701 atcttactct ctcacgctga ctgggattca cgtgaaaagg aagcccagag agtagtccag
    32761 cgtgtaactg ctaattgaat attaccatag agagtcaacc cagatagctc agactttagt
    32821 tgaaaatcaa gctcgtattg agggaatcta taaatacttt agccttagca tgccagacta
    32881 tttttactgg caattagagc ggaaagcttc gccttatata tcagtctctc tgtatgaaaa
    32941 tgttgatgac ctctatgttc gaaatgattt tgtaactgga gtggccatcg cttttcaaga
    33001 ttacaaggaa gtctatgttt ctactaaaga caaacgtagt ggagaaaaaa tcagggctga
    33061 ggatttcaaa ccagcaggaa atagttttgc cattccgatg tcagatccag tgtcagatca
    33121 agatttagga gtgatttaca tctccttgga tcctgctgtt ttataccatg ccattgataa
    33181 tactagaggt catactccga tggcagtaac agtgacctca ccttttgata cggagatttt
    33241 tcatattggt gagacagttg ataaggagag tgaaaattgg ctcgttggct taacatctca
    33301 tggctatcag gttcaggtgg cagttcctaa aaactttgtt ttacaaggaa cagtgactag
    33361 ctctgctttg attgtgggtt tgagccttct ctttattgtc attctttatc tgactttgag
    33421 gcatactttt gctaattacc aaaagcaggt agtggattta gtagaatcca ttcaagtcat
    33481 tgctcaaggc gaagaggggc gtcggattga catttccgaa aaagatcagg aattactcct
    33541 aatcgcggag acgaccaatg atatgttgga tcgattggaa aagaatatcc atgatattta
    33601 ccagttagag cttagtcaaa aagatgccaa tatgcgagcc ttgcaggcgc aaatcaatcc
    33661 tcattttatg tataatacgc tggagttctt gcgcatgtat gcagttatgc agagtcaaga
    33721 tgagttggca gatatcattt atgaattcag tagtctcttg cgtaacaata tttccgacga
    33781 aagagagacc cttctcaaac aggaattaga attttgccgt aaatacagct atctctgcat
    33841 ggttcgctat cccaagtcca ttgcctatgg tttcaagata gatccagagt tagagaatat
    33901 gaagattccc aagtttacct tgcaaccgct ggtagaaaac tatttcgcgc atggtgttga
    33961 ccacaggagg acagataatg tgattagcat caaggctctt aaacaggatg cttttgtgga
    34021 aattttggtg gtcgataatg gtagaggaat gtcggctgaa aagttggcaa atatccgaga
    34081 aaaattaagt cagagatatt ttgaacacca agccagctac agtgatcaaa ggcagtctat
    34141 cgggattgtc aatgtacacg agcgttttgt gctctatttt ggagaccgct atgccattac
    34201 gatagagtct gcagagcaag ccggtgttca gtatcgtatt acaattcaag atgagtagaa
    34261 agggagaaaa tgtataaagt attaatagta gatgatgagt acatggtgac agaaggtctg
    34321 aagcgtttga ttccctttga taagtgggac atggaggttg tcgcaacagc cagtcatgcc
    34381 gatgaagatc tagaatatgt tcaggaaaat cctgtcgatg tcatcatttc cgatgtcaat
    34441 atgccagaca aaacagggct tgatatgatt cgggagatga aagagatctt accagatgct
    34501 gcctatatcc tgctctcagg ttatcaggag tttgattatg taaaaagagc aatgaacctt
    34561 agtgtggtgg actatttggt caagcctgtt gataaggtag agctgggaaa tctgctggag
    34621 aagattgcag gtcagctcgg cgagagaggg aagaaaagtc agactcttag tcaagaatta
    34681 gacggggctg gatttgttag ttatttaggg gataaggaga attggtggat aggtctatcc
    34741 aaggaaaaac aaggttcctt caccactccc tactatgtct tgggtcaaga ctggcagatt
    34801 ttcatttctg accaacccct agatggttta gtcgttacac cttttgaagc tccttatcaa
    34861 gaacactttg aacgctggaa gctgaatgct gagaaagccc tcttttacgg ctctgtaaat
    34921 ctgcagcagt ctgagagtct ctttgcctat tacgaaccga tttatagggt tatcattcag
    34981 ggaaatctca atcaaatcgt agaagagtta aatcttttgg agaaggtagt tcttgaaaat
    35041 acacctcgtg ttccgattac caaacagctt tttattcagt ttgtcatgga tgttttccat
    35101 ttatttgaac atctcaaagc tgatgacctg acagacatcg tcaaaacggt tcatgctatt
    35161 caatccttcg atgaattggt tccttatatc aaggaaaccc tgaccagctt ttttggtcaa
    35221 taccgtatga atgaaaatgt ggtcagtgtg ctggaagtta ttgggcgtga ttatcagaaa
    35281 gaactttcca tcaaggatat cagtaaggat ctctttatca atcctgtcta tctagggcag
    35341 tcgattaagc gagaaaccga ttcgactttt gcagagttac taaacaaaca acgtattaag
    35401 gctgcccaac aacttttgct ttcaactagt gatagcatcg aagatatttg ttatgctgtt
    35461 ggttacagta acattggata tttctataaa gttttccgaa aattgtgcgg aaaattgcca
    35521 aaagcctacc gaaaacaggt agaaactata ctataagatt tgtattcctt tacaaaaggt
    35581 gctataatat aaataatatt atcaggaggt tctatcatga aaaagaaacc aatttatcta
    35641 tgggtcttgc taatcttgtc tgcccttatt tcagttccgt ctctgtttgg aattgtgagt
    35701 cccttgccta gtaaagaagc ccttcgtgct gctcagaaac aagttgcagg ggtcaatgct
    35761 cagcaattag aagaccagct taattatacc tatagagtag cagaagcatc tcattctatt
    35821 tttaatgttg ctttgattgt gctatctact attttagtgg tcgtagcgat tgtcttcctt
    35881 gttcgtaaaa atttgcaata tgcaaactat acttacgttg gctatgtttt gttagctatt
    35941 attggttcga tttatggcta tgttggttta caagacgctg tgcagttggt tcaagatgag
    36001 agcatgcgtt tgacagtgag tattggttca aaagctgtta gcattttcta tatcgtcatc
    36061 aatgttctct tcctagccct tgtcttctat aagatgtggc gacaacagaa agccttggca
    36121 gaagaagagg aaacagaaga gcttacctaa gtattgacaa aaaagaacta tcaagataca
    36181 atcttggtag ttgttttttg attatagata aaatcatgga ggtacatatg aagacaattt
    36241 ctttagttta tattagtttg agtggcaaca ctgaaagttt tgtgacgcgc ttgaaagact
    36301 atctcttgtc ccagtacaaa gggattgagg ttcaaaagat tcatatcaag gatttggtca
    36361 aggaaggcaa aaatttctat gaaatggacc atccctatgt cgcttttttg ccgacctatc
    36421 tcgaaggtgg gaatggcgtg gataacggag atgttgagat tttgacgaca ccggtgggag
    36481 attttattgc ctatggtaac aatgctagta agtgttttgg tgtggttggg tcaggaaatc
    36541 gtaactttaa taaccaatac tgcctaacag ccaagcaata cagtcaacgc tttggcttcc
    36601 ctgtattggc tgactttgaa atgcgaggca tgctggaaga tatcaaacat gtcgcagcta
    36661 ttatcgcaga tttgtatgag ttggaaaagg agaattaata ctcaatgaaa atcaaagagc
    36721 aaactaggaa gctagtcgca ggttgctcaa agcacagctt tgaggttgca gatagagctg
    36781 acgtggtttg aagagattct cgaatagtat aaagttctta taagatgtgg ttgaagttgt
    36841 tcaactgttt tttgagtata aacagtcttt aagaacgtaa aaaagcataa gttcaggtct
    36901 tcaaaacctt gttcttatgc tttttatcat agaaatattt gctgaatttt ctcttgaaat
    36961 gaaaccttat cttcatctcg cgcttgtccc ttaccctgct tttccgattg cgagtgcgta
    37021 gataaagaag atggcgaagc caaagaggaa aatcaatccc gcaatggcaa ggtgtttgag
    37081 ccaagaagga agatttttgt tttcacgtgt taccaaggcg taattcaaaa gagcaaagaa
    37141 aggtgttgtc aggaaagagc caatcatggc aaagcggagc atggttgaaa cctgaccagc
    37201 gaagaacttg ataatgacga taccgatgat agcagtgatg gtcatccaga tgttcaaaga
    37261 tttacgattg tcctcttttt gactgattag cagtcggaga gattcctgat taacgcgaga
    37321 atagccatcg ataacagtta taactgttcc aaagatacag aggaaggcaa taaaggtaat
    37381 caagtaacgg gaccattcgc caagaacaga ggcatacatg cccacgaatt gagagatgta
    37441 tttggctgaa gcagcttcaa ccgcctgccc tgtaggatac tgaatcagtg ctcccagtgc
    37501 cacaaagaag acggctagga tagctgttcc aatataacca gtgttaaagt caaacagagc
    37561 gtcttctttg ttaaagttga cggtttttct cttttcagct gaccaaagtg aattgatagc
    37621 tgaaatttca ataggagcag gcatccatcc taggagggag acgatgaagg gcagagctgc
    37681 catttgccaa ggtgtcttct cgacaaaatc agaactgtat tctggatgct tgaccgctgc
    37741 tatgataact gcaagaacag tcgcaatggt taaggcagac ataatccatt tgaccatgcc
    37801 gtctaaaagt ttgtagcctc caaagagtag catagcccaa atgattgcaa cgagaatgag
    37861 ggaccactga gtaatgctaa gtccaatcat tgggaaggca ctggcgatga tagctgagca
    37921 cagaatggca acaccagccg tgttgaccat agccgaaaag acattgagaa taaagaaaat
    37981 ccagagatag agttttcctt tttcggcata accttcaacc aaagtctttc cagtatcagc
    38041 tgtgtattca gcaccaaaac ggaaaaatgg atatttaaag acattggcta agatgaccaa
    38101 gagaagtaga gaccaaccgt aagaaccgcc agcttgagtt gaggatacaa tgtgggaacc
    38161 tccaacagcg gcagttgcca ttaggattcc aggtcccatt gcttttagct tgcttgccca
    38221 ggttgattga tttaaggaaa tagcttgcga catgataaat actccttttt gaattttcag
    38281 aataatctgt atatgcaatc tatattctac aaaaaatttt ggaaaaatgc aagaatattt
    38341 tgaaaaaaga tagaaaattt acaaagaaaa tctgaaataa ctgttatgat atagcagatt
    38401 gaaactagaa tagtacactt ttgcttctaa aacattgtta gaaatcgatt tgactgtcct
    38461 gattgattta tcctgttctt atttcatttc actatagtaa ggtgcagcag gataaagcaa
    38521 aaccgagaag tttctttctc ggttttgctt attatgaggt tcctattttc tatgctccaa
    38581 gagttgattg atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat
    38641 gagatagaca atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaggggaa
    38701 ccaaccagca agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag
    38761 agtggcacga agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat
    38821 accgatggct gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg
    38881 ctgatccatc acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc
    38941 ataaatgagt gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc
    39001 gtgaaatact tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt
    39061 gaagagtagg tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc
    39121 ttgaggtgag agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg
    39181 cttggcaaga gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg
    39241 gtttctgcta gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact
    39301 agatagacct gatcatcgat ttttcctttg attttttctc tttggtccag attttctgcg
    39361 aactcgatga ctttctggac tttttcggtt tcttgaggtg cttggacaat cagcttttcc
    39421 tcctcgtaag tctcactaat ctgtagttct actttcataa atttctctcc ttgtttttca
    39481 tacaaaatta atctcacttc ttgtacacct ttattaatac tcttcaaaaa tctcttcaaa
    39541 ccacgtcagc gtcgtcttgc cgtaggatag ttgttgactt tgtcagtttt atctacaacc
    39601 tcaaaacagt gttttgagct gtctgcgtct agctttctag tttgctcttt gatttttatt
    39661 gagtatacca ctattttact ccctctggca agggactttg tctatgtgga gggattgggc
    39721 tcctatgtgg tggagttttt ctgttctttc tgaaatatgg tataatagca ctaattaatt
    39781 tctaggaaaa tagatacaga aaggggctga aagatgtctc atattattga attgccagag
    39841 atgctggcaa accaaatcgc agctggggag gtcattgaac gtcctgccag tgtggttaaa
    39901 gagttggtag aaaatgccat tgacgcgggc tctagtcaga ttatcattga gattgaggaa
    39961 gctggtctca agaaggttca aatcacggat aacggtcatg gaattgccca cgatgaggtg
    40021 gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa atcaagcaga tctctttcgg
    40081 attcggacgc ttggttttcg tggtgaagcc ttgccttcta ttgcgtctgt tagtgtcttg
    40141 actctgttaa cggcggtgga tggtgctagt catggaacca agttagtcgc gcgtgggggt
    40201 gaagttgagg aagtcatccc agcgactagt cctgtgggaa ccaaggtttg tgtggaggat
    40261 ctctttttca acacgcctgc ccgtctcaag tatatgaaga gccagcaagc ggagttgtct
    40321 catatcattg atattgtcaa ccgtctgggc ttggcccatc ctgagatttc ttttagcttg
    40381 attagtgatg gcaaggaaat gacgcggaca gcagggactg gtcaattgcg ccaagcaatc
    40441 gcagggattt acggtttggt cagtgccaag aagatgattg aaattgagaa ctctgaccta
    40501 gatttcgaaa tttcaggttt tgtgtcttta cctgagttga ctcgggctaa ccgcaattat
    40561 atcagcctct tcatcaatgg ccgttatatc aagaacttcc tgctcaatcg tgctattttg
    40621 gatggtttcg gaagcaagct tatggttgga cgttttccac tggctgtcat tcacatccat
    40681 atcgaccctt atctagcgga tgtcaatgtg catccaacta agcaagaggt gcggatttcc
    40741 aaggaaaaag aactgatgac cctggtttca gaagctattg caaatagtct caaggaacaa
    40801 accttgattc cagatgcctt ggaaaatctt gccaaatcga ccgtgcgcaa tcgtgagaag
    40861 gtggagcaaa ctattctccc actcaaagaa aatacgctct actatgagaa aactgagccg
    40921 tcaagaccta gtcaaactga agtagctgat tatcaggtag aattgactga tgaagggcag
    40981 gatttgaccc tgtttgccaa ggaaaccttg gaccgattga ccaagccagc aaaactgcat
    41041 tttgcagaga gaaagcctgc taactacgac cagctagacc atccagagtt agatcttgct
    41101 agcatcgata aggcttatga caaactggag cgagaagaag catccagctt cccagagttg
    41161 gagtttttcg gacaaatgca cgggacttat ctctttgccc aagggcgaga tggactttac
    41221 atcatagatc agcacgctgc tcaggaacgg gtcaagtacg aggagtaccg tgaaagcatt
    41281 ggcaatgttg accagagcca gcagcaactc ctagtgccct atatctttga atttcctgcg
    41341 gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag aggaagtggg cgtctttcta
    41401 gcagagtacg gagaaaatca atttattcta cgtgaacatc ctatttggat ggcagaagaa
    41461 gagattgaat caggcatcta tgagatgtgc gacatgctcc ttttgaccaa ggaagtttct
    41521 atcaagaaat accgagcaga gttggctatc atgatgtctt gcaagcgatc tatcaaggcc
    41581 aatcatcgta ttgatgatca ttcagctaga caactcctct atcagctttc tcaatgtgac
    41641 aatccctata actgtcctca cggacgtcct gttttggtgc attttaccaa gtcggatatg
    41701 gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc tccgtgagtt ggggaaatat
    41761 taaaagtata aaaaagtctg ggaaaaatgt tcaaaatcag aaaaacgcat aaaatcaggt
    41821 gttcaaaaac cttgatttta tgcgttttat catagaaata tttacttcat gttttcctaa
    41881 ttcttttcga aactcttttt aaaccacgtc agttttatca gtaatcttaa aacagtgttt
    41941 tgagctaatt ttgccagttt tgtctgtaac atcgaagttg tgtttgacca ctctgcgact
    42001 ggtttcctag tttgctctat gattttcaca gagtattaaa ttgcgatttt gccaagtttc
    42061 tttattcgtc taaaagtaga gtctgttcta tgcgtctaat gtacgaatta ggttgaccat
    42121 ttcaatagct ccttgtgcac actcagaacc cttatttcct gctttagtgc cagctcgttc
    42181 tatggcttgt tcaattgtat ctgtcgttag cacaccaaac ataacaggaa tttcgctatt
    42241 taaactgatt tgggcgattc ccttagatac ctcgctacat acataatcat aatgacttgt
    42301 attccctcta atgacagctc ctaagcagat aattgcatca tattttttac tttttgccat
    42361 ttttgatgca atcagtggta tttcaaaagc tcctggaatc caggctacct cgatatcttt
    42421 ctcgtttaca ttctctcttt tgagattatc tagtgctcca gataataatt ttgaagttat
    42481 aaattcatta aatctcgcta caacaatacc tattttaata ttgtttgcta ctaaattacc
    42541 ttcataagtg ttcatttatt tttcctccat atttaaaatg tgacccattc gatttttctt
    42601 tgtttctaaa taaaaactat cgtaagcatt ggcttctatt tcgattgata ttctactgga
    42661 aatggtaatt ccatattttt ctaactgttc aaccttgtca ggattatttg tcagtaaatg
    42721 aagtgactga agtcccagat ctttaagtat ttgtgctcca atatggtatt ctcttaaatc
    42781 accttcaaag cctaatgcaa gattggcatc aagcgtatcc atgccttgat cttgtaaatg
    42841 ataggctttt aatttattga taagtccaat tcctcgtccc tcctgtcgca agtaaagtaa
    42901 gacacccgaa ccattctcaa caatcatttt catagcttta tcgaattgct gtccacaatc
    42961 gcaacgtaaa gagcctaaaa catctcctgt taaacattcg gagtggaccc gacataatac
    43021 attggcttca tcctctatat ttcccataat aagagcaaga tgatgttccc catttagttt
    43081 atctatatag ctaattgctt tgaaattacc gtatctagta ggcatattga cagttgaaac
    43141 tcgttctacc agctgatcat atacttttct atattcttgt aattctttga tggtaattag
    43201 tggaatgttg tgtttcttcg agaactgaat taaatcatct gttctcatca ttttgccatc
    43261 atgattcatt atttcacaac ataggccaca ctcttttagt ccagctaatt ttaataaatc
    43321 aacagttgct tctgtgtgtc catttctttc tagaacacca cctttttttt caattaaagg
    43381 aaacatgtgt cctggcctgc gaaaatcaga gggtgttata tcttcagcta cacacatacg
    43441 tgcggtcagt cctctttcct cggcagaaat acctgtggtc gtttctttat aatcaattga
    43501 aactgtaaaa gcagtcttat gattatctgt attgttttca atcataggtg aaagcattaa
    43561 ttgattagct aaactttcgc tcataggcat acaaattaat cctttggcat aagtagccat
    43621 aaaattaaca ttttctgttg tagctgcttg tgcagaacaa attaagtctc cttcattttc
    43681 tctatcctta tcgtctataa caagaacaag tcgtcccttc tgcaatgctt ctaatgcttc
    43741 ttgtattttt cgatattcca ttgactgatt atcctttctg ctaaaatcca ttttgatata
    43801 atagttcctt agatatttct gattttggag aattatccat cagtttttgc acatatttac
    43861 ctaagatatc attttcaaga tttactgtac tcccgacttg tttactctta agaatggttt
    43921 gttcccaggt atgagggata acagatactg aaaagtttac tttggagact ttagcgacag
    43981 tcagactaat gccgtcaatt gtaatagatc ctttttcaac tattaaatct aaaatttctt
    44041 tttgtgtgtt gatttgatac catacagcat tatcatcttt ttttattgac gagatttttc
    44101 ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag tcgaccgttg acagataagg
    44161 ctctttctag attcacctca cttccatgtt ttaatagagt aagagctgtt cgactccatg
    44221 tttcattcat tacatcaact gtaaaggatt gatgattgaa atgagtaact gtaagacaga
    44281 taccatttac tgctatacta tcacctaaat ggatatccgt taatattttt gaggctttaa
    44341 ttgatagttt acaattacga gagtctttct gtattctttc aacttttccg atttcttcaa
    44401 ttattcctgt gaacatggat aaatcacttc actttctatg agatagtcat ttcctatttg
    44461 agaaaaagca taaggtttca atctaatagc gtcatttggc aaagaaatgc cttcacctcc
    44521 gataggaaac ttggcactgc ctccaaaaat ttttggtgca atatatattt tcagctcatc
    44581 aacaatttgt tgttccaaag cactccaatt cattagactg cccccttcta gaactaggct
    44641 atcaatctgc atgtttccta gatgttgcat taaactcgat aagtctatat gattgccttt
    44701 tttctttatg gaaagtattt tacagccatg attttgatat agcttcattt tatttttgtc
    44761 ttcagaggaa gtggcaatgt aagttttaat atcatttgct gtttttacga ttttagaggt
    44821 aagaggagtt cgtaaatgtg tatcgcatat gatacggata ggatttttcc cttcctccaa
    44881 tctacatgtc agcaaaggat cgtcttgaat aacagtgttg actcccacca taattgcact
    44941 aacatggtgt cgtaactgat gcacatgctt tcttgcttct tcttcagtaa tccatttgga
    45001 ttgatttgtt ttagtggcta tttttccatc cattgacatt gcatatttca taaaaacata
    45061 gggtacatgc tgggtaatat actttctaaa actttttatt aagttaagac actcattttc
    45121 taaaattcca acagtaactt gaagattatt ttcctcaagt atctttactc cttttccaga
    45181 tacaatagga ttacagtcta ggcttccaat gactactctt gtaataccac tatcgattat
    45241 agcatctata cagggaggtg ttttcccgaa gtgacaacag ggttcaagtg ttacataaag
    45301 cgtcgctccg acaggggatt ctctacagtt tttaagagca tttctctcag catgtgggcc
    45361 accaaaaaac tcatgataac cttgtccgat gatgtgatta tcttttacaa taactgcgcc
    45421 gaccatagga ttggggttga cgtaaccagc ccctttttgt gccagtttta ttgctaattt
    45481 catatatttt gaatcgctca tctcactacc tccaaaaaat ataccttgaa taggggacta
    45541 ctcaaggcat acaaaagaaa acttatgcga ttaacaaaaa tgctctgaaa tgacaagtaa
    45601 tcatttcaga gcacgcaaaa agcacaaata tacttttatc ttctttcatc cagactatac
    45661 tgtcggcttt ggaatttcac caaatcatgc ctttcggctc gtgggctata ccaccggtag
    45721 ggaattgcac cctgccctga agatagttat tcaattacag atgattatag tacttaattt
    45781 tgaatatgtc aacagataaa taccgattgt ttttgatata ctgtatttgt gataatcgat
    45841 tctcgctcct cggataaaga aaatatgata tactagataa acgaaataag agagaaggaa
    45901 tactatgtac gcatatttaa aaggaatcat taccaaaatt actgccaaat acattgttct
    45961 tgaaaccaat ggtattggtt atatcctgca tgtggccaat ccttatgcct attcaggtca
    46021 ggttaatcag gaggctcaga tttatgtgca tcaggttgtg cgtgaggacg cccatttgct
    46081 ttatggattt cgctcagagg atgagaaaaa gctctttctt agtctgattt cggtctctgg
    46141 gattggtcct gtatcagctc ttgctattat cgctgctgat gacaatgctg gcttggttca
    46201 agccattgaa accaagaaca tcacctactt gaccaagttc cctaaaattg gcaagaaaac
    46261 agcccagcag atggtgctgg acttggaagg caaggtagta gttgcaggag atggccttcc
    46321 tgccaaggtc gcagtgcaag caagtgctga aaaccaagaa ttggaagaag ctatggaagc
    46381 catgttggct ctgggctaca aggcaacaga gctcaagaaa atcaagaaat tctttgaagg
    46441 aacgacagat acagctgaga actatatcaa gtcggccctt aaaatgttgg tcaaatagga
    46501 gcagagaatg acaaaacgtt gttcgtgggt caagatgacc aacccactct acatcgccta
    46561 tcatgatgag gagtggggcc agcccctcca tgatgaccaa gcgttgtttg agttgttgtg
    46621 tatggaaacc tatcaggcag gcctgtcttg ggaaacggta ctcaacaaac gccaagcttt
    46681 ccgagaagcc tttcatagct atcaaattca ctcagtcgca gagatgactg acactgaatt
    46741 ggaagccatg ctggagaatc cagctatcat tcgaaataga gccaagattt ttgctacacg
    46801 cgctaacgcc caagcctttc tacagttaca ggcagagtac ggctcttttg atgcctatct
    46861 ttggtctttt gttgagggga aaactgtcgt taacgatgtt cctgattatc gccaagcccc
    46921 agctaaaaca cccttatctg agaaattagc caaagatctc aaaaaacgag gcttcaagtt
    46981 cacaggccca gtcgccgtat tgtcttttct acaggctgca gggctagttg atgatcacga
    47041 gaatgattgt gagtggaaag gtcttaaatg atgtctaaca aaaataaggg aattctgatt
    47101 tttgcgattc tctatacagt cctctttatg tttgatggcg ttaaattgct ggcttcttta
    47161 atgccatctg ccattgcaaa ttatcttgtt tatgtagttt tagctctata tggctccttc
    47221 ttgttcaagg atagattgat ccaacaatgg aaggagatta gaaagactaa aagaaaattc
    47281 ttctttggcg tcttaacagg atggctcttt ctcattctga tgactgttgt ctttgaattt
    47341 gtatcagaga tgttgaagca gtttgtggga ctagatggac aaggtctaaa tcagtctaat
    47401 attcaaagta cctttcaaga acaaccacta ctgatagctg tttttgcttg tgtcattgga
    47461 cctctggtag aagaattatt tttccgtcag gtcttattgc attacttgca ggaacggttg
    47521 ccaggtttac taagcattat tctggtagga cttgtttttg ctctgactca tatgcacagt
    47581 ttggctctat cagagtggat tggtgcagtt ggttacttag gtggaggcct tgccttttct
    47641 attatttatg tgaaagaaaa agagaatatc tactatcccc tacttgttca catgttaagc
    47701 aacagcctct ccttaatcat tttagctatc agtatagtaa aatgaaatga gaacaggaca
    47761 aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatatactgt
    47821 aatatgtgat gaaaatgcca gtaatgatac cgagaaaaaa gctgagaaac ttttcccagc
    47881 tttatttgtt atagtcaaag agaatgactt gttcctgtgc atctacatga gcatggaccc
    47941 caaagggtac aattgctctt ggagttgcgt ggccgacatt cagattatag acaatcggga
    48001 tattgctgtc aatgatatcc aatagtgcct ctttatagtc gtcatggaaa gtttcatcca
    48061 taggttttcc gaccaagagt ccattgatga ccgcgaatat gccagtgtcc tttaaagtta
    48121 gcaacatctt tttgaagtct tctggcttag gcttttcttc gcttgtttcg agcaagagga
    48181 ttttcccttc ccagtctgac aagtcaggga aaagtttgta tttttggcag agctccgtgc
    48241 tatctgcgta tcgagagttg tcaaagatat cgtagaggga ttcgaggcaa ccaccgagga
    48301 ttttcccctc gaactgggca cttccttgca acaagtcaaa acctgtattt gtatgactga
    48361 cacgaggtgt tcccagggcc gtgggactaa aatcagttcg ttcctcatac caaacgtcac
    48421 tagggcggat ttctgaaatt cttcccgtct caatcaattc tttaaagtag tgaaggctat
    48481 aggctagcat ttctttgtct aattcacaaa tgtctgctaa aaaggattga ccataaaaag
    48541 tcttgattcc taatttatgc aacatgaggt ggttcatggt tgtatccgag aagccaagaa
    48601 aaattttttg tttgataacc ttttggagtt ggtcattttc aaaaagataa ggtagcaagc
    48661 gataggtatc gtctccaccg atggcacata ggatcatgtc gatgctatca tcagaaaagg
    48721 catgaatcaa attctctgca cgagcttcag gatggtcctt gataaagtct aatcctttta
    48781 acgaatgggg caaaaagatg ggattgagtc tcagatcctt gagacgttgg atacccaagt
    48841 ccacttcgtg tttgacaaaa tcctctccga taatgccact agataaacta acaataccaa
    48901 tagtagaaac catatctcat cctcctagaa atagattgag cctattttat cacaaaatat
    48961 aagagaaagc tatgtgggat ttcagaagaa tacttttaat actcttcgaa aatctcttca
    49021 aaccacgtca gttttatttg caacctcaaa gctgtgcttt gagcaacctg cagctagctt
    49081 cctagtttgc tctttgattt tcattgagta taactcaaaa aagtaagtga aaaagcaacc
    49141 gcacctgcag ttgcttttat cgttttctta ttcttgatag cgtgttggtc ctgcacttgc
    49201 actacggata ttcaagcgtt tcttgagata gaagcgaagg gctaggaggg ctgctccaat
    49261 aatagctagt ggcaatggat ccagtactgg gttaaggcta gctggtagga agcttgttgc
    49321 aaagaagaca agcaaccaaa ggaacataga agctaggata actagtacag atttccagaa
    49381 aggtggacgt tgactgcgat ccatatctgg tccatagtat tggtaaacaa agtagtacat
    49441 caagtagaag gcaaatccac caaccagtcc aactaataga agagtaatca atccatagcc
    49501 gaaagcttga tctgccgcaa agaaggttgt gagggcgctg acaagggcaa agaggctagt
    49561 gatgaaaaga gctgagtcca taatcatcag ttttggatca tcattttctt ttggatgctc
    49621 tttttcgtac tgctctttga cagtgaagct atgagcccaa tgagttggtg cgccgtatag
    49681 ggaacgggca gttgtacctt tagattgctc ctcaaggatt tggggaatga cttcctcaaa
    49741 aatagtctgg atttcagcgt ctgttttccc atctttgatg aattgttggg tagcaatgtg
    49801 gacaaactct tggtttttct tagttaattt ttgtagatca atttgagaca taggaactcc
    49861 tcttagaacc attttttatg gatgagatag agagtgagcg agacactcat agcaaaggcg
    49921 ataaagacga ttaaccagaa ggcatttggc tctccgttta gggggatttc attatcctta
    49981 aagttcatcc cgtaggcaga aaagaccatg gttgggatgg acatgacgat ggtcacaagg
    50041 gccaaggttt tcatgatgtt gttctggttg ttagaaatga tagaggcaaa ggtctctgtc
    50101 atagaatgca agacgtttcc ataaatatct gccatctcga tggcctgttg ggtttcaatc
    50161 agggtgtctt caagcaggtc ttcgtcctca aggtatttct tgatattgct ggttgaactg
    50221 gtcaatttct taatcacgcg ctcatttgtt ttgagggagg ccttgaaata gacgatagtt
    50281 ttttccaatt ccatgagctc aatcaattct tcattacgag ttgattgatg cagttgactt
    50341 tcgatttgtt cactcttgcg gtcgattgaa cgaagggctg ttaggtaaag ctctgcattg
    50401 cgataaagaa tttgaaagat aaaacgtgaa cgcatgaagg tatagaaatt acgcaatcga
    50461 cggttgataa agacatcaag gacaggtagt ggttccaaac acgtagtgat aatggtttcc
    50521 tcagtgatga taataccaag cgggatggtt acgtagtagg tgcggttatt tctttcctcc
    50581 gtgaccggca cgtctacgat aatcagggta tactcgtctt caatggtaat acgagacatt
    50641 tcttccgcat cgagcggtgc tcgaaggtcg gcaatatcaa tatcgaaggt gttggcgatt
    50701 tcgagtgatt cattttgagt cggattgacg agattgatcc aagtacccgg ttcaagcgta
    50761 tcgatctctt taaattcagt tgttgtagag agaaaaactt gtttcatatc ccttatcctt
    50821 tctcattttt cagatttttt cacactgtac tattatacta caaaatcggc cttttgggta
    50881 atagaatctc actttttttg gtataatggt aagcaataat ggactagaaa gaacaaagat
    50941 gcaagataaa attgtcattc atggggcgcg tgcccataat ttaaaaaata ttgatgtgga
    51001 gattccgcga gacaagttgg ttgtcgtgac tggcttgtca ggttcaggga agtccagtct
    51061 ggcttttgat accctctatg cggagggaca acgtcgctat gtagagagtt tgtccgccta
    51121 cgctcgtcag ttcttgggaa atatggaaaa accagatgta gatgccattg atggtctcag
    51181 cccagctatt tccatcgacc agaaaacgac tagtaaaaat cctcgctcga cggtgggaac
    51241 gacgactgaa atcaatgact atctgcgtct cctctacgca cgtgtgggga cgccttactg
    51301 tatcaacgga catggagcta tcaatgcttc ttctgtggag caaatcgttg ataaggtttt
    51361 ggagttacct gaacgccagc gcttgcagat cttggctcct gtcatccgca agaaaaaagg
    51421 ccaacataag agtgttatcg agaaggttca gaaagacggg tatgttcgtg tccgtgtgga
    51481 tggggaagtc tatgatgtga ccgaagtgcc agagttgtct aagagcaagc aacacaatat
    51541 cgatgtcgtg gttgaccgta ttgttatcaa ggagggcatt cgtagccgtc tctttgattc
    51601 cattgaagct gcccttcgta tcgcagaagg ttatgtgatt atcgacacca tggacgattc
    51661 ggagttgctc ttctctgagc attatgcctg tccagtttgt ggatttactg tcccagagtt
    51721 agagcctcgt ctcttctctt tcaatgctcc ctttggctct tgtagtgagt gtgacggctt
    51781 ggggattaag ctggaggtgg atactgattt ggtagtgcca gatgccagca aaacgctacg
    51841 tgagggggct ttggcacctt ggaatcctat ctcatctaac tactatccaa atatgctaga
    51901 gcaggctatg acagcctttg gagtggatat ggataagccc tttgaggact tgtcagaaga
    51961 agataagaac ttgattctct acggctcgga tggcaaagaa tttcattttc actatgagaa
    52021 tgaatttggc ggtgtgcgcg atattgacat tccttttgag ggagtcgtca ctaatatcaa
    52081 gcgtcgttac catgagacta acagtgatta cacgcgcact cagatgcgtc tctacatgaa
    52141 tgagctgacc tgcggaacct gtcaaggcta tcgtctcaat gaccaggcct tgtctgtccg
    52201 tgtgggcgac cagcaagggc cacatattgg agaaatctca gacctgtcta tcgctgacca
    52261 cttggacttg gtgagccagt taactttgtc tgaaaatgaa gccatcattg ctcgtcccat
    52321 tctcaaggaa atcaaggatc gtttgacctt ccttaataat gtgggtctta actatctaac
    52381 cctgtcacgt tcagcaggaa ccctttcagg tggggaaagt cagcgcattc gtttggcaac
    52441 ccagattggt tccaacctat caggcgtcct ctatatccta gacgagccgt caatcggtct
    52501 tcaccagagg gacaatgatc gcctgattgc cagtctgaaa aagatgcgtg acttgggcaa
    52561 tactcttatc gtggtggaac acgacgaaga taccatgcgt gaggctgatt atctgattga
    52621 cgttggtcct ggtgccggtg tttttggtgg tgagattgtt gcagcaggta cacctaagca
    52681 agtggctcgc aacagcaagt ctatcacagg tcagtacttg tcaggcaaac gtgtcatccc
    52741 agtaccagaa gagcgccgtg tcggaaatgg tcgttttatt gaagtgatag gagcgcgtga
    52801 gaacaacttg caaaatgtca cggctcgctt tccactagga aaatttatcg cagtgacagg
    52861 tgtgtcgggt tcagggaaat cgactctaat caacaacatt ctcaaaaaag ccattgccca
    52921 gaagctcaac cgtaattcag acaaacctgg taagtttaag actattacag ggattgagca
    52981 tgtcgaccgt ttgattgata ttgaccagag ccctatcgga cggacgccga ggtctaaccc
    53041 agctacctat acaggagttt ttgacgatat acgtgacctt tttgctcaga caaatgaagc
    53101 caagattcga ggctataaga aggggcgctt cagtttcaac gtcaagggag gtcgctgtga
    53161 agcttgctca ggtgacggga ttatcaagat tgagatgcac ttcttgccag atgtttatgt
    53221 ggcttgtgaa gtttgccacg gaacccgcta taacagtgaa accctagaag ttcactacaa
    53281 ggaaaagaat atttcgcagg tcttggatat gacggtcaac gatgcggtag aatttttcca
    53341 acacattccg aaaattcaac gcaaactcca gaccatcaag gatgtagggc taggctatgt
    53401 gaccttggga cagccagcta ccaccctttc tgggggagaa gcccaacgta tgaagttagc
    53461 tagcgaactc cacaaacgct cgacaggaaa atctttctac attctggatg agccgacgac
    53521 agggcttcat acagaggaca ttgctcgcct gctcaaggtt ttagctcgct ttgtagacga
    53581 tggcaataca gtcctcgtca tcgagcacaa tctggatgtt atcaagacgg cagaccatat
    53641 cattgacttg ggacctgagg gcggtgtcgg tggtggaacc atcatcgtaa caggaactcc
    53701 agaagaagta gctgccaacg aagccagcta tacaggacac tatttgaaag gaaagttaca
    53761 tcatgaataa acgcgtacaa gcatttctag ctaaaatgca agaaaaagaa ctagatggta
    53821 tcatcatcaa caatcttaaa aacgtctatt atttgactgg tttttggggc tcaaacggaa
    53881 cagtctttat cagccgtgac cgtcaggtct tagtgacaga ctctcgctat atcatcgcag
    53941 ctaagcaaga aaccagtggt tttgagattg tggctgatcg tgatgaattg gctgtcattg
    54001 taggaattgt taaggacatg ggcttgactc gtatcggttt tgaagatgag atttcagtgt
    54061 cttattacca ccgtatgcag gcaacttttg caggtttgga cttgcttcca caaactcagt
    54121 ttgtggaagg tcttcgtatg attaaggatg aggcagagat tgcagcgatt cgcaaggctt
    54181 gttttatctc agaccaagct ttccgcgatg cgcttgactt tatcaaacca ggaaaaactg
    54241 aaattgagat tgccaacttc cttgatttcc gcatgcgtga gttgggagca tctggcttat
    54301 cttttgatac gatcctagct agcggtatca attcttctaa accccatgcc catccaatgc
    54361 acaaaccagt ggagttggga gaagccatta ccatggactt cggctgtctc tatgaccact
    54421 atgtcagtga tatgacccgg actatctatc tagggcatgt tagcgatgag caggcagaga
    54481 tttacaatac ggttctaaaa gctaaccaag ccttgattga ccaagctaag gcaggcttag
    54541 gtttccgtga ctttgacaaa atccctcgtg atattatcat tgaggcaggt tatggcgact
    54601 actttactca cggcattggc cacggtattg gtctggatat ccatgaggaa ccctacttta
    54661 gccagacttc tacagaaact attaagacag gtatgacctt gaccgatgaa ccaggtatct
    54721 atatcgaagg caaatatggc gttcgtatcg aggatgatat cctgattaca gagacaggtt
    54781 gtgaattatt gaccctagct ccaaaagagt tgatagtcat ttagttgttt gtcaagaaaa
    54841 aagtacgaaa atgacgaaaa aagtcaaaaa aaattaaaaa taggt
//
LOCUS       DAVDHZ010000010        52146 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000010 DAVDHZ010000000
VERSION     DAVDHZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.010"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(102..1229)
                     /locus_tag="VUR46_000746"
     CDS             complement(102..1229)
                     /locus_tag="VUR46_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5456207.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKKDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(1944..2495)
                     /locus_tag="VUR46_000747"
     CDS             complement(1944..2495)
                     /locus_tag="VUR46_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456208.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(2744..3568)
                     /gene="nadE"
                     /locus_tag="VUR46_000748"
     CDS             complement(2744..3568)
                     /gene="nadE"
                     /locus_tag="VUR46_000748"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET5456209.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(3565..5025)
                     /locus_tag="VUR46_000749"
     CDS             complement(3565..5025)
                     /locus_tag="VUR46_000749"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET5456210.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(5141..5629)
                     /locus_tag="VUR46_000750"
     CDS             complement(5141..5629)
                     /locus_tag="VUR46_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456211.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(5619..5828)
                     /locus_tag="VUR46_000751"
     CDS             complement(5619..5828)
                     /locus_tag="VUR46_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5456212.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(6214..6393)
                     /locus_tag="VUR46_000752"
     CDS             complement(6214..6393)
                     /locus_tag="VUR46_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456213.1"
                     /translation="MMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQYLVVITTII
                     LLCFFTLKKSKKYSF"
     gene            complement(6726..6935)
                     /locus_tag="VUR46_000753"
                     /pseudo
     CDS             complement(6726..6935)
                     /locus_tag="VUR46_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773444.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6951..7796)
                     /locus_tag="VUR46_000754"
     CDS             complement(6951..7796)
                     /locus_tag="VUR46_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456214.1"
                     /translation="MEVINVSKHYGHSIILKDINFALNKGEIVGQVGRNGVGKSTLMK
                     ILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLI
                     QELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVL
                     KNLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSAT
                     DRDIFITKQEFGDIVQEEGLSITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIY
                     LNRSK"
     gene            complement(8179..8907)
                     /locus_tag="VUR46_000755"
                     /pseudo
     CDS             complement(8179..8907)
                     /locus_tag="VUR46_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(9153..9464)
                     /locus_tag="VUR46_000756"
     CDS             complement(9153..9464)
                     /locus_tag="VUR46_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456215.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(9479..10765)
                     /locus_tag="VUR46_000757"
     CDS             complement(9479..10765)
                     /locus_tag="VUR46_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET5456216.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            11389..11571
                     /locus_tag="VUR46_000758"
     CDS             11389..11571
                     /locus_tag="VUR46_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET5456217.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            11581..11946
                     /locus_tag="VUR46_000759"
     CDS             11581..11946
                     /locus_tag="VUR46_000759"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET5456218.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            11943..13133
                     /locus_tag="VUR46_000760"
     CDS             11943..13133
                     /locus_tag="VUR46_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET5456219.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(13314..14540)
                     /locus_tag="VUR46_000761"
     CDS             complement(13314..14540)
                     /locus_tag="VUR46_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5456220.1"
                     /translation="MAKTRYSGVFVDTKGKYFYETELGIDRISGKRIRKKSRKDSNGK
                     PFSTAREAYLELTRVKREYHKAHTYANYNMTVKQFILDCYIPYYKSYVEESTYAVRIK
                     NLEKIAERFYNKTLRGLTIEDIQNYRIWLLSSKDENGSGYSQAYASLIFGMFRKSLDY
                     AVEMGYLETNISKKAKAIPKGKAIVPYWTKVEFERVIAQICLDDFYEHLNFVMLWTFF
                     MTGIRVNEGMALWWNDIDFDKKRMRVHHMLILKSRKNWQRNAYTKTSDGKRIISLDDD
                     TISILKRWKDRQKEIGLGNETDFIFTYDSLPMIKSTLARIIQRYSELANVKRIQGKGL
                     RHSNASYLINEFNVSVLILSKRLGHSSPEITLKHYSHLWRGADESIAEIMSGNISIHT
                     APKTKIQFNGNQNLKR"
     gene            complement(14544..14738)
                     /locus_tag="VUR46_000762"
     CDS             complement(14544..14738)
                     /locus_tag="VUR46_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HET5456221.1"
                     /translation="MKPLISKDDLIKLGYKKHTAISIIQAVKQDLVYNKGIPFYNNRR
                     LGLVPRERVENLIGVKLDEE"
     gene            complement(14746..15558)
                     /locus_tag="VUR46_000763"
     CDS             complement(14746..15558)
                     /locus_tag="VUR46_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456222.1"
                     /translation="MTRELYNTKIIQYNSNTFEVIYYRKAKFRRLGETDTTVSNTSKS
                     PSEKELYQQANRIKRRIRHYMLCNDFDLFWTLTFNDEKINSHDYLIVKKKIRTWLKAQ
                     REKYGKFHYIFIPELHKNGRLHFHGVTGGFSPKLTKARNTKTGRLINKNGKQVYNVDS
                     YQLGFSTVTKIDSSEKVANYITKYITKDLLAIPSGYKQPKYFSSRGLIKPIVSYENLE
                     RNYFEGLTPSFSVGHLDNLEYKEDIAIYNLSIDDNEEIIQNSTDTRIKIRKE"
     gene            complement(15662..17071)
                     /locus_tag="VUR46_000764"
     CDS             complement(15662..17071)
                     /locus_tag="VUR46_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HET5456223.1"
                     /translation="MIVSKIKRKLSKYDCREYTPTYLSVSETIESRKERQYSLIKKLL
                     KVFLISVIITFLSSHFPLLSTIYKISIVISSVLLDIFIWYIVVKFLFSTYSPIWKYRF
                     LSILRLATERLDLIQLPSNKIQIKTVEWKFYKENERIIIELNPSGTIPNIQQVKEITR
                     RLTEFLIQATNEDWNILESTVQNSYVVIKYGKSNPRYTVSELFKITDEDYYINYKPIK
                     LYDNICFDIASEANQQIIIAPSGAGKSLYLATLAGLLIKQGHSISLIDAKQTSLGATF
                     ENLGIPVARNAEEIILLLEQMVFEMEDRYKRYFAFSSVDFGTTYKHFSLPAHYLIFDE
                     VLAALECGTSAQQKEMVRLLKILALKSRASGQGLLVLASQKLLASDLPRAVTEQCQTR
                     IILGNSSSISEETFYSVMGKEKIDLLAEYRGGVGKGYILTPKTNGIKYFETPYFDLDS
                     IDFKNKIRDFQTIPRKQIE"
     gene            complement(17068..17505)
                     /locus_tag="VUR46_000765"
     CDS             complement(17068..17505)
                     /locus_tag="VUR46_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456224.1"
                     /translation="MENNFGKVSFNSPSLKNLLIGTSNVEHTPTSAFVIECRDVPKRN
                     EKNEVIDGTISKKVLLALQSEIVKAIQEVGGDLSSIKPFTIEIYNDESFLKKINNELI
                     IAKTIDLEGALLALKWVSDGRNGGAYREFKLIISEIKLSGAKS"
     gene            complement(17690..18376)
                     /locus_tag="VUR46_000766"
     CDS             complement(17690..18376)
                     /locus_tag="VUR46_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456225.1"
                     /translation="MSSKQFNNLCKQKFPNSCHFIFKKCSQRIQKKYKDLKLKRHIDL
                     HSDEKLIGKILNYSNLSDLSRNNPYLITPSVLNYFVNEEHYFNDENEVLWGRDIDEYL
                     EDFFIEMILDIQGIPEYSKHLLNLSLTNTGDIKEYFQQHFPLASSSYNELKDKFIDFT
                     YNQFDTIEILENDSVFLFRKKDSVTLSPKNKESYLSYQKLPEKLDLLAKYILLPMIDK
                     LTLESLIYRK"
     gene            complement(18381..18596)
                     /locus_tag="VUR46_000767"
     CDS             complement(18381..18596)
                     /locus_tag="VUR46_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5456226.1"
                     /translation="MISYKPFYETLFKQGKTEYELIFHHGLSSNTLHRMKKGKPITTA
                     TLDTLCFILNCNVYDVITYIPDDIEEV"
     gene            18711..20075
                     /locus_tag="VUR46_000768"
     CDS             18711..20075
                     /locus_tag="VUR46_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456227.1"
                     /translation="MKLEDFQTFPFKSVQEYISDKEKAIKFSFLLQGDEPDRSELMKL
                     IYKDIFEWYDDKVHSGDTLITYRTAIFRKYYGKSYSKLSRDKQREILNIIKSYTEYDD
                     DFPFEFELDNKEKNVYQICNNYQIGNFGIFPKGRINPKRAQSPYNDYFDLTLSVIWDL
                     YDGTLTPDDEFKRAILDEKEYFDQFKDFETFLSDNFLTVFFDDEGYLIRLSEIDDFEE
                     YVRISNQIIYTRGLAILTYLQSMYDDNSELPTQQLEEKKTVPRPTTKELAHRTLKIAE
                     EEIDKISKFDEYYNELEFNLHKEKFETTKKRIYGAIVLFLFIVSLFFYTSEIIMFIWI
                     LSTVLYVADKIRIVKEKIKYDKIINATQEKYREEKKKLLSTLRKEYYSIPTEFRTYNH
                     ISGIQYFLNADIASNLQQAIHYYSNEYNSKRMQDQIYSLHHSNTILQDRIKELELERE
                     LEKY"
     gene            20096..20488
                     /locus_tag="VUR46_000769"
     CDS             20096..20488
                     /locus_tag="VUR46_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456228.1"
                     /translation="MTKFNLQSNQIYSELSKFEIEEILYNATKQLNGSVERQSSEEIS
                     YSGQGNFFDYMKHPGLSRYTCWQVLVTISDLGDKRKVELTAVGESPISYLLNNFLSFI
                     TFYTLFQRHRNLNFGISKEKAKYLSNLL"
     gene            complement(20674..22236)
                     /gene="guaA"
                     /locus_tag="VUR46_000770"
     CDS             complement(20674..22236)
                     /gene="guaA"
                     /locus_tag="VUR46_000770"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET5456229.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREINPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPSDFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIQK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRVLGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            22378..23076
                     /locus_tag="VUR46_000771"
     CDS             22378..23076
                     /locus_tag="VUR46_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5456230.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGEHFEFYLENN"
     gene            complement(23119..24015)
                     /locus_tag="VUR46_000772"
     CDS             complement(23119..24015)
                     /locus_tag="VUR46_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET5456231.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMILAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLIPLKDLFLEK"
     gene            complement(24024..24959)
                     /locus_tag="VUR46_000773"
     CDS             complement(24024..24959)
                     /locus_tag="VUR46_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET5456232.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKVGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(24956..25681)
                     /locus_tag="VUR46_000774"
     CDS             complement(24956..25681)
                     /locus_tag="VUR46_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET5456233.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(25765..26400)
                     /locus_tag="VUR46_000775"
     CDS             complement(25765..26400)
                     /locus_tag="VUR46_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET5456234.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLHGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQMEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(26402..27229)
                     /locus_tag="VUR46_000776"
     CDS             complement(26402..27229)
                     /locus_tag="VUR46_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5456235.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAKTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYKRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(27251..28308)
                     /locus_tag="VUR46_000777"
                     /pseudo
     CDS             complement(27251..28308)
                     /locus_tag="VUR46_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813133.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            complement(28451..28642)
                     /locus_tag="VUR46_000778"
     CDS             complement(28451..28642)
                     /locus_tag="VUR46_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456236.1"
                     /translation="MKEILICDIIKRKGLHKKVGRMKMQRRQNRNQGGLAFRFMKGLV
                     NFLGVIAIGAIRDLWRYSC"
     gene            28831..29442
                     /locus_tag="VUR46_000779"
     CDS             28831..29442
                     /locus_tag="VUR46_000779"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET5456237.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            29488..30216
                     /gene="rlmB"
                     /locus_tag="VUR46_000780"
     CDS             29488..30216
                     /gene="rlmB"
                     /locus_tag="VUR46_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET5456238.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNLEKVKELAT
                     EKKVSISWISKKSLSEMTEGPVHQGFVLRVSEFAYSELDCILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(30255..31166)
                     /gene="trxB"
                     /locus_tag="VUR46_000781"
     CDS             complement(30255..31166)
                     /gene="trxB"
                     /locus_tag="VUR46_000781"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET5456239.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(31232..31456)
                     /locus_tag="VUR46_000782"
     CDS             complement(31232..31456)
                     /locus_tag="VUR46_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET5456240.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(31534..32277)
                     /locus_tag="VUR46_000783"
     CDS             complement(31534..32277)
                     /locus_tag="VUR46_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5456241.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(32277..33077)
                     /locus_tag="VUR46_000784"
     CDS             complement(32277..33077)
                     /locus_tag="VUR46_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5456242.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMDISAPDTVQTDVKGDLR"
     gene            complement(33235..33591)
                     /locus_tag="VUR46_000785"
     CDS             complement(33235..33591)
                     /locus_tag="VUR46_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET5456243.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNREAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(33585..34115)
                     /locus_tag="VUR46_000786"
     CDS             complement(33585..34115)
                     /locus_tag="VUR46_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET5456244.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(34115..34609)
                     /locus_tag="VUR46_000787"
     CDS             complement(34115..34609)
                     /locus_tag="VUR46_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456245.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            34744..35190
                     /locus_tag="VUR46_000788"
     CDS             34744..35190
                     /locus_tag="VUR46_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET5456246.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYINQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            35187..35834
                     /locus_tag="VUR46_000789"
     CDS             35187..35834
                     /locus_tag="VUR46_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET5456247.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMITGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(35855..36436)
                     /gene="pdxT"
                     /locus_tag="VUR46_000790"
     CDS             complement(35855..36436)
                     /gene="pdxT"
                     /locus_tag="VUR46_000790"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET5456248.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(36437..37312)
                     /gene="pdxS"
                     /locus_tag="VUR46_000791"
     CDS             complement(36437..37312)
                     /gene="pdxS"
                     /locus_tag="VUR46_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET5456249.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLRKDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(37464..38843)
                     /locus_tag="VUR46_000792"
     CDS             complement(37464..38843)
                     /locus_tag="VUR46_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET5456250.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            39138..40061
                     /locus_tag="VUR46_000793"
     CDS             39138..40061
                     /locus_tag="VUR46_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET5456251.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            40121..40726
                     /locus_tag="VUR46_000794"
     CDS             40121..40726
                     /locus_tag="VUR46_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5456252.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDVIFDDFRIFVKITEKLRNAQELLRKDAEEFNWENL"
     gene            40744..41988
                     /locus_tag="VUR46_000795"
     CDS             40744..41988
                     /locus_tag="VUR46_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5456253.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(42105..42362)
                     /locus_tag="VUR46_000796"
     CDS             complement(42105..42362)
                     /locus_tag="VUR46_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET5456254.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRVV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(42404..44440)
                     /locus_tag="VUR46_000797"
     CDS             complement(42404..44440)
                     /locus_tag="VUR46_000797"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET5456255.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTLKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(44700..45617)
                     /gene="glyQ"
                     /locus_tag="VUR46_000798"
     CDS             complement(44700..45617)
                     /gene="glyQ"
                     /locus_tag="VUR46_000798"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET5456256.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQCCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(45810..46571)
                     /locus_tag="VUR46_000799"
     CDS             complement(45810..46571)
                     /locus_tag="VUR46_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET5456257.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QPVIWSDFNAATQIIRESAVPTYTNNRRVVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLHIVGHELAHWSEHFLDDFDGSDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTDKTLPLLNWFVQQKLIEKEI"
     gene            complement(46844..47686)
                     /locus_tag="VUR46_000800"
     CDS             complement(46844..47686)
                     /locus_tag="VUR46_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET5456258.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(47800..49191)
                     /locus_tag="VUR46_000801"
     CDS             complement(47800..49191)
                     /locus_tag="VUR46_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET5456259.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYGIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(49426..49803)
                     /locus_tag="VUR46_000802"
                     /pseudo
     CDS             complement(49426..49803)
                     /locus_tag="VUR46_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            50036..51013
                     /locus_tag="VUR46_000803"
     CDS             50036..51013
                     /locus_tag="VUR46_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET5456260.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGKQVQLPIQQAPHT
                     MTEEVAAFSHMIQQPDLNLYQTWLDDAGSVHELLYTMRQTAGIRFEAEK"
     gene            51010..52092
                     /locus_tag="VUR46_000804"
     CDS             51010..52092
                     /locus_tag="VUR46_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5456261.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLNNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
BASE COUNT        16056 a        10904 c         8902 g        16284 t
ORIGIN      
        1 acttttttat agtcgctata agatgacctt atctatagct ttttatatat aattatatat
       61 tcagacatac tattatcaat tttgtcgcag ggaggaatct gttaacgcac ccattcacca
      121 ttatcattga ctctatagcc atctatactt gtattgaccg ctaactcacc cgatgcattt
      181 acataatacc atttaccacc aacttggaac cattgattaa ctttcataga accgttgctg
      241 ttgaggtagt accatgaacc attaacttgt acccaacctg ttgccatgga accatcagta
      301 ttataaaaat accacatacc attttcttgt ttccagcctg ttgttggagc aactgcttta
      361 gctggttcta ctgctacatc tgttccttgg ttagatgtaa cagatacagg atacgaagga
      421 atagatgatt gctcaggaac aacaactttt tcaggttctc tcgtccctct ccttatacgt
      481 ctttttacca tctctttagt aatttgacga gaagtagttt cttcaattgt tccatcacgt
      541 tcatctacag catagattgt agtaagagta attttaccaa tttctcctac ttcttgacct
      601 ttatcaagag ttgggccatc gagatattct gtttcgattg gaatttcttg gacaagaact
      661 tggggcttgg ttcctttttt aacaactctt gtttgagagt cttttttttg acttaaagta
      721 ctctcagtta cttgtccact ctttccatct acatcataag ttatcgttgt aactgttttc
      781 ccattctttc ctagagtaat ctcttgctcc tgtcctgcag aaaggtcatt gtctgcttca
      841 tatttagtag caaatggaac aagaacttct tcaaccttgc ttttagctgg aactttgata
      901 actgtatccg tggcttcttt tctatcaaca gtaacctgtt cggtaacatg accagtctct
      961 ggattaacat cgtaggtcct tgtcgtagtt acatagccat cctctccatc aattgtaaca
     1021 ggattttcac tacggtcttt tgtttcatct ttttcataac gaattcgcgt acttgaaatt
     1081 ttcttggtta ctaccttagg tttagtcgct acttttacaa taatatcccc attgtcagcg
     1141 tcatcatact ctattccctc ttctttatct ctagtatcat ctctgacata ttgaatccca
     1201 tcagcagcat gaacaaaact tgtattcaga ttcctcctaa aaataaactt agcccgatta
     1261 ccgcagaacc aaaaatcttt ccgagtttac gtattgcata gcgcttatta gtattagatt
     1321 ttgccattac atcctacttc tagtatagca tcttttctat caaacgttaa acaatatact
     1381 ttatatataa aatagactta gaatgatata ttgattattg aactaacact ttaactatat
     1441 cgtaatcaat ctcatatata aaggattgca gacatcttat ctaaatacat gctaatatat
     1501 ttagatacaa acattccaac ttgataattt tcactcatct ttcatcattc cttatacaac
     1561 tatgcagtat aaatagaata gttttctcat cagaatgaga ctattttaat attagataat
     1621 ttgatagaaa aaacatgaat aaaattggtt gaatttaatt ccctaactcg atagaggatt
     1681 ctattttaaa tttaacaaca gctaggatta cactataaaa agtacattac cacctgttcg
     1741 gctggagaat ctagtcgatt agctccctct tagttacaag cttaaagcga ttttttaact
     1801 aatactaaac cagattaaag aaggaactag aacatctgtc ttgtactaat caatatgcta
     1861 ttttaaagtt tcaaataaac ttggaatgct aattattata tttacaataa atagttgact
     1921 tcgatagaaa cagaaaatag aattcaacat tcttccctac ttataccata ataaataaga
     1981 tccgcaagat agccttttct ctctacacca ttaacaatgg tttgtagata ggacattcca
     2041 gccttttcca tgacacgacc tgaagctggg ttgagactgg cataacgtgc tctgaccttt
     2101 tgaaaacctg cttgagtaaa acaaaagtcc aagatagctt tcaaagtctc tgtcatcata
     2161 ccatttcccc agtaagcctt gcctaacaca tagccaattt cacagcttaa atcagcctcg
     2221 tctatcttaa caatgctgat atctcctatc acttgctctg ggttttcttt tagacaaatg
     2281 gcccatttat aatagttgag attagtatag gaagcaaccc aattgcaaat cgagtttcga
     2341 gtgatttcga catcaggatg gggatcccag gtaacatagg tcagattctc agcggatgaa
     2401 gcccaatttt gaaacatggc ttctgcatca ctctccacaa atcttcttaa aatcaaacgt
     2461 tctgtctgta atatttgcgt accgatagat ttcatgatgc tacctcactt ccttatttct
     2521 atgctcgtag taaaaaggct caactcagta acagctagaa aacgagtttg tcttctaatt
     2581 tcttgacgca gtcgctgcct ggtttgaaat gcgctctagc aatctttttc aaacctagtc
     2641 atcgttgcag gggtaagacg atgaaatcga actcttcgag ttaccgaatc tgcctcattt
     2701 tcttatttca agataagagg ctgaaaacct ccaatggagg tttttactcc caaaagtcat
     2761 caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag ttttcaatgg
     2821 tcgcttgagc ttctgggctg attgttttgc cttctaggta atcgtcaatc tctgcatagg
     2881 tgactccaag tgcgacttcg tcagctaggc ctggtttgtc ttcttctagg tctgccgttg
     2941 ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt tttccttggc
     3001 gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac ttggtaaaga
     3061 aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta tgggaaccag
     3121 caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg ttgaagtctg
     3181 aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgac tccttgatat
     3241 tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca tctgcttcat
     3301 cagcttgcac tccgtatggc agacggacag cgataaattt gtagctgtcg tctcccgttt
     3361 cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt gagtcttgtc
     3421 ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga tatcttttta
     3481 agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg acacccagct
     3541 cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg cttccttgcg
     3601 catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat ccactggata
     3661 gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt ctttacgggc
     3721 ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt ctttgaagat
     3781 atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt atgtataggt
     3841 cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat aagtgatata
     3901 gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct tcttacctgg
     3961 cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct gaccagtttc
     4021 atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat aagctgtaat
     4081 cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga ggttgaggat
     4141 agtattttcg tccaaatcat tagaagcata aatcttagcc tctgtaaatc cagcctcgtc
     4201 cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa tccgcacacc
     4261 cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg gtacaccgat
     4321 gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg cagcgtaagc
     4381 cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat gggttcccaa
     4441 aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg caccaccaat
     4501 caccgctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac gtgtcccaaa
     4561 ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg tcgccaccaa
     4621 ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt gggctagagg
     4681 tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt gggcagaacg
     4741 aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat gataaccaag
     4801 cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat agttcacaat
     4861 tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc ggaaatatac
     4921 ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca tcatgttaat
     4981 ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt tcctacttcc
     5041 ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa attagtacta
     5101 ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca ctctccaatt
     5161 catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta agaccaagat
     5221 tgccaataaa gacccatgga aggtaaatga tataagtaat gacccaagca gacaggtatt
     5281 taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc tgcaacatca
     5341 aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa tgaaaacgac
     5401 tatagtaggt cactcccaga taacgggcac gattgaaaaa gtaaaatgtc cctatgatga
     5461 taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa atgatataag
     5521 ataggagcga caaagcaatg cagatataga aactttcaga gcccgcttta ttgaacagtt
     5581 gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc ttcttcctcc
     5641 caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca gagcgagaga
     5701 ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac cccgacagcc
     5761 tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa ttttaaattt
     5821 ttagccacct tcgtcctcct tatagtttta atactcatct actcttaaaa aatccaaaac
     5881 caacacaagc tatcagctat ttattataac cccattaatt tgcactccag tattatcttc
     5941 agccgaaaat cagtatttta ggttgtttga aataaacttc ctagtttact cttttatttt
     6001 tatttagtat tagctttagt aggatctttt aaacgagttt ttattgctta tatttcttgt
     6061 ttagtttagt tggtttcata tcactattat ataatgcttt tggaaatgag cctagtataa
     6121 gtcaaaaacg tgttgaatag tgaaagcagg agcataccaa gatgactgat ttttttattg
     6181 tattttaggt atgcaaaata atactaaatg aaactaaaat gaatacttct tgcttttctt
     6241 gagagtgaaa aagcacaata aaatgattgt agtgattacc acaagatact gactaataga
     6301 catcgtattt gaagccacaa atacaggtaa agaataaaaa ggaagaagtt caattgcttt
     6361 gataaacaaa tcattactag tattcatcat catcgtattt aatatattag ggataaagag
     6421 tagtaaagct actaaaatac caagccactt ttcaatttgt ataaatagaa aatgtaagat
     6481 aatagaaaat aaaacaggac taacaaaatt gtattgacta caatagctac tataaaatct
     6541 aatcctaaat cacctggaat acccaattta cttactatga ctagtaacac aatgccattc
     6601 aaagcataaa taatggaaac tgagatggca tatagaaaat tagacaagac gtaaatcatc
     6661 cgattcttct gttgattata aaacaaactt accgtattgt gggaaaaatc tctactaatg
     6721 actcgattag catgtataac agccattaac ataccgagca tagcataaaa gtttgaaata
     6781 tgcttaatac caagcgatgt cccttgagtc tttagaataa agaatgtaac caatatcggc
     6841 ggtataaacg agataagcaa accgagatat attacgcctg atgaatataa atttcttata
     6901 ttttccttaa gaaaattaaa tttatttaat ttcatgatta taaccttcct ttattttgaa
     6961 cgatttagat aaatatcttt gagcgtctct tttttagttt caaaatcaac tactttaata
     7021 gagttttcgt taaaaaattt aaaaagctca ctactttgaa tattcccaga catagtaatg
     7081 ctcagtccct cttcctgaac aatatcccca aattcttgtt tggtaatgaa aatgtctcta
     7141 tctgtagctg atgaaaaagc tatctcaaac aagaaattat gactatcttt tcctactttt
     7201 tgaaatgtca aaagcccgtt ctccaagaaa agaaccctct cacaaatttc ttcaatatct
     7261 tctaatttat gactcgatat taaaattccc acattttcat gtaaagctaa attttttaga
     7321 accgataaaa ctatttgtga tgattcaata tctaaaccat tagtcggttc atctaaaatc
     7381 aatatatcag gttccgtaac gagagttaga agcaaagcta atttttgttt tgtacccaaa
     7441 gaataggtct ttactttttt attaatagac tgagtcaaat ctaactcttg gatcaaactt
     7501 ctaaatcttt cttgattgta gtcaacacca tataaatttg acaaatattt taaattctct
     7561 aaacctgttt tagataaaaa taattttggt tcttcgatta aatacccaac attatcactg
     7621 cttataatat tacctgaagt cggttgatta ttctgaacaa gaattttcat caacgtactc
     7681 ttaccaactc catttctccc tacttgacca acaatttcac ccttgttaag tgcaaaattt
     7741 atatctttga gaatgattga atgaccataa tgcttactta catttataac ttccattttg
     7801 taattcctcc attaatattc tcggttttct ctttgattct cattaatttt aaaaagttgc
     7861 gcctcttttt aacaacatta tatcatatat ctaacttaat gcaatatata aatgtcattt
     7921 tgtaaaattt tattaataaa aaactctcta caacaaaata atagagagtt ttctgcttat
     7981 taattttttt caaaatatct aagacatcgc ttctttgttt aatttgatag gctttgatac
     8041 ctaagctccg actttatcac ttaaaaaata aaaaaggaca gctaatctct tgcgcatcaa
     8101 gggatttcgc cattctttaa tctcgtttaa gtgttgtata tggagctttg cataattttt
     8161 taacactaaa caactacatt aagcacgaac tgtgacgctg gttccatctt ccttataaag
     8221 attgataagc ccctctttaa gagctcgaac catgtctcct gattgaacag gttgtgggac
     8281 tttaatagtc aatagttcca ttggatttgg agcgcggtcg attttattgc ctttggcatc
     8341 atgcaaatct tcaatatagg tttcaaaatg acggaaacct ggaccataaa actcaacttg
     8401 gtccccttcg ttaatgacat ttcgttgacg aatagttgct gtttgtgccg catcatcata
     8461 agaaaccact tcagcgacaa acttgtactc aggaatttta cgacgagcac caaacaactg
     8521 ctcattttca gatggtgtac catagtaaaa tcctgtagcc agttcacgtt gggcaaactt
     8581 ccacatctcg tccaccaagt cttgtttgat agcttcaaac ttttcaggac tttcaagata
     8641 ggcatccaca gccgccttgt agcagttggt tactgttaat acatagtgaa tagactccat
     8701 acgtccttcg atttttagac tgtccacacc attttcaatc atatctggaa tgtggtcaat
     8761 catagacatg tcaacggctg acattgaaaa ttcttctgga atctcaccct gcaaactctt
     8821 acgttctttc ccaaatggca tatcgtaaag gtcgtacttc caacggcatg actgagaaca
     8881 tccaccacgg ttggcatcac gcatactcta gacggattgt tttgacaatt ctaacctttt
     8941 agactttgca taataactgt taaacagtcg aaaattatcc cagttttaac aagtagtcaa
     9001 aataccagat aaaggaaaaa agtctttaaa atcttaaaaa cgcatagtat caggtattga
     9061 acaatcttga tattatgcgt tttattgtgg gaagatttac ttcattttct cttggaattg
     9121 agttttctcc tacttcaaaa ctagatgatt tgctatttaa aatagcgttc cttatgattt
     9181 tggcaacctg gattaaagcg agaaaaacaa aagaggcaac ttaagctttc tttatattgc
     9241 ttatatgtta gtagttttag acaaacacca cataaaatag gcttatcctg tatcaaagat
     9301 aagggataag gctcaaaagg gtgattttct aatgaatcat gacaccgata acaagcataa
     9361 tactttttac aatcatagca ttgtaaagca ataatatcca gcttgctatg gtaatgaatg
     9421 catcttgttt gcttatccac taagaaaccc tgtgcctcta tcatttcctt ttcctttctt
     9481 aagctcgaac tgtgacgctg gttccatctt ccttataaag attgatgagt ccttctttta
     9541 atgcacgaac catgtctcct gattgaacgg gttgaggcac cttaatagtc aatagttcca
     9601 ttggatttgg agcgcggtcg attttattgc ctttggcatc atgcaaatct tcaatatagg
     9661 tttcaaaatg acggaaacct ggaccataaa actcaacttg gtccccttcg ttaatgacat
     9721 ttcgttgacg aatggttgct gtttgtgccg catcatcata agaaaccact tcagcgacaa
     9781 acttgtactc agggatttta cggcgagcac caaacaactg ctcattttca gatggtatac
     9841 cgtagtagaa acctgttgcc aattcacgtt gggcaacctt ccacatctcg tccactaagt
     9901 cttgtttgat agcttcaaac ttttcagaac tttcaagata ggcatccaca gccgccttgt
     9961 agcagttggt tactgttgat acgtagtgaa tagacttcat acgtccttcg atttttagac
    10021 tgtccacacc attttcaatc atatctggaa tgtggtcaat catagacatg tcaacggctg
    10081 acattgaaaa ttcttctgga atctcaccct gcaaactctt acgttctttc ccaaatggca
    10141 tatcgtaaag gtcgtatttc caacggcatg actgagaaca tccaccacgg ttggcatcac
    10201 gcatactcat gtggtttgaa agagtacaac gtccagagta tgaaatacac atagctccat
    10261 ggacaaaggc ttcaatttca acatctgtac gtttgcggat ctcagctaat tcttccattg
    10321 aaacctcacg cgctaaaacg acacgagtca agcctagctc tttccagaac tcaagggttt
    10381 catagttagt ggcactggct tgggtagaaa ggtggatttc aaggcctggt gcttcagtcg
    10441 ctgcaatcat aatcaaggct gggtcagata cgataactgc tgcaatcccg atatcacgca
    10501 gtttacggaa ccactcacca gcaccagctt catttccttc gtgcataacc atattagccg
    10561 ctacatagac cttggcacca tacttggccg caaactgcac gccttcttcc atctgttcga
    10621 aagtaaagtt tcccgcacgg ctacgaagac cataggcctg accaccgata aagacagcat
    10681 ctgctccata ctgaacagct acctttagct tctctaaagt ccctgcaggt gataaaacct
    10741 caggacgttt taatgttttt gtcataattt ctcctatttg caatataaaa gtttgacatt
    10801 tttccttctc attttatagt aaataaagga taaaatcaag cctagacgga ttgttttgac
    10861 aattctaatc ttttagactt tgtataataa ctattaaaca gtcgaaaatt accccagttt
    10921 taacaagtag tcaaaaagtc taaaaaagta aaaaccagta tcccaagata ctgactcgta
    10981 aaaatatata aattagtcct tagatgacta ctcccactct gttgctccta taatggaaaa
    11041 ggattgatac agtctagaat atcgcttttt tatttattat tatgatataa aactgttaga
    11101 attgattttt tgttttatac ccaaatatga atagagacgt agctaataag ttgaataaca
    11161 tatttggaaa aatgagaaat agcaatatta ctagaacttt tagaaacaat caatatttaa
    11221 aaagaaaaaa gctcaaagaa tttattaaac catgttataa tagatatagc tataatttta
    11281 tttataacaa gaggatagaa atgaccgaat tagaaagaaa aaatcgaaaa attagctaag
    11341 aaatactctg ataacttaaa catcaaagtt caagagagag ttcgtgaaat ggcaaatgat
    11401 aataagagcc attatttgat atacagagtt ttaggtattt catttgaaga aggagaaaat
    11461 atcgatttgt atcaaaataa aggtcgtttt ttatacaaat atgctggttc atttttagaa
    11521 gaagctgcag tactatcctt taacgaaaaa tttggtacag aaaatactta aaaagttaac
    11581 attcctaatt ctgaaagtac aaaacctaag acttttgaaa ttgattgttt agtcggagaa
    11641 aaacacgcat acgaaataaa atggtgggat gcaactacag atggagacca tataactaaa
    11701 gaacacacta gaataaaagt tattcataac aaaggatata taccaattcg gttaatgttc
    11761 tactatccaa atagaactca agccataaaa attcagcaaa ctttagaaac attgtataac
    11821 ggtattggag ggaaatatta ttatggagat tctgcctggg aacatttaag agcagtgacc
    11881 ggtattgatt tacttagtat tctaacagat attgcaaata aaaaaacagg ggtaaaatca
    11941 aaatgacagt attaaaagga gataacttag aaatattaaa aactattgaa tcctcaagta
    12001 ttgatttaat ctatatggac cctcctttct ttacacagaa aacccaaaaa ttatctaata
    12061 acaaaaatat tatgtattca ttcgaagata cgtggacttc gattgaggat tacaaagaat
    12121 ttttgtctgt aagattagaa gaatgcaaaa gagtgctaaa aaatagtggc agtattttcg
    12181 ttcattgtga taaaattgca aatcatcata ttagattaat tttagataat atctttggag
    12241 cagatatgtt tcaaagcgaa attatatgga actataaacg gtggtctaat tcaaaaaagg
    12301 gattattgaa caatcatcaa aacatttact tttattcaaa gtcaaaagat tttaaattta
    12361 atacaatttt tacagagtat tcttctacta caaatatcga ccaaatacta gtggaacgaa
    12421 aacgagatgg aaactctaaa actatatata aggttgataa taatggtaac tatattctag
    12481 caaaagagaa aaatggagtt cccctttcag atgtttggaa tataccattt cttaatccaa
    12541 aagctaaaga aagagtaggt tatcctacac aaaaacctat tctgttatta gaacaaatta
    12601 taaagattgc tactgataaa aatgatatag ttttagaccc gttctgtgga agtggaacta
    12661 ctttagtagc ctccaagatt ttgaatagaa attatatggg gattgattta tctgaggaag
    12721 ctatcaatat aactcagcaa cgtctggaaa atgttataaa aacaagttca aatttattga
    12781 ataaaggaat cgaagcatat agaaccaaaa ctgaggaaga ggaaaacatt cttaaattat
    12841 tacaggcaaa aattgttcaa agaaataaag gaattgatgg ttttttacct aaacattttc
    12901 aaaaaaaacc gatacctata aaaattcaaa aaaataatga atgtctgaat gagagtatct
    12961 ctttattaca gaatgctata aactccaaaa aacttgattt tggagtagtt ataaaaactc
    13021 attcagataa tttattattt gattttgata cgattcctga aaatataata gtagttgacc
    13081 attttgaact tacaatcgaa aaatggttaa gtaaaagtca acagttacta tagtttgcaa
    13141 attatttaca gaaagaacaa aaaatgctct gaaacactga tttcaaagca ttttttgtta
    13201 gtttaaaatt actcccactc aattaacaat ttcataggtt tagtgccaga aaaccttgat
    13261 ttattaaggt ttacaatgcc ttttaaatat atttggcggg atttctggcg gggttatctt
    13321 tttaggtttt gattcccgtt gaattgaatt tttgtttttg gagctgtatg tatggatata
    13381 ttcccactca ttatttcagc aatagattcg tcagctccgc gccaaaggtg tgagtaatgt
    13441 ttcaaagtaa tttctgggct agaatgacct aaccttttcg acaaaattaa gacagataca
    13501 ttaaactcgt ttatcaaata agaagcgtta ctatgacgaa gtcctttacc ctgtattcgc
    13561 tttacattag ctagttcaga atatcgttga ataattctag ctagtgtaga ttttatcatt
    13621 ggaaggctat catatgtaaa tataaaatca gtttcattgc ctaaaccaat ttctttctgt
    13681 ctgtctttcc aacgctttaa aatagaaatc gtatcatcat ctagggaaat aatacgtttg
    13741 ccatcacttg ttttggtata ggcatttctt tgccagtttt tccttgattt tagaataagc
    13801 atatgatgaa cacgcatacg ctttttatca aaatcaatat cattccacca aagtgccatt
    13861 ccttcattta ctcgaatacc tgtcatgaaa aaagtccaaa gcataacgaa attaagatgt
    13921 tcataaaaat catcaagaca gatttgagca ataacacgct caaattctac tttagtccag
    13981 tatggaacga tagcctttcc tttcggaata gctttggctt tcttagagat attagtttcc
    14041 aaataaccca tttctacagc ataatcaaga gactttctaa acataccaaa gattagacta
    14101 gcgtaggctt gagagtagcc agaaccgttt tcgtctttgc ttgacagtaa ccatatccga
    14161 tagttttgaa tatcttcaat agtcaaacca cgtagtgtct tgttataaaa tcgttcagca
    14221 atcttttcaa gatttttgat tctgacagca taagtacttt cttccacata cgatttataa
    14281 tatggtatat aacaatctaa aataaactgc ttgacagtca tattgtaatt agcgtaagta
    14341 tgagctttgt gatactctcg ttttacccga gtcaattcta aatacgcctc tctggcagta
    14401 gaaaaaggct taccgttgct atcttttcta cttttctttc taatacgttt accactgatt
    14461 ctatcaatgc ctagctctgt ttcatagaaa tattttcctt tcgtatcaac aaacacaccg
    14521 ctataacgtg tttttgccat ttgttattcc tcatctagtt ttacaccgat aaggttttct
    14581 accctttccc gtgggactag tccaagtcta cggttattgt agaatggtat acctttatta
    14641 tacaccaaat cctgctttac cgcttgaata atactaattg cagtatgttt cttatatcct
    14701 agttttatca agtcgtcttt actaatcaat ggtttcatac gcttactatt cctttctgat
    14761 ttttattctt gtatcagttg aattttgaat aatctcctca ttgtcatcta ttgatagatt
    14821 gtaaatcgca atatcttctt tgtactcaag attatctaaa tgacctactg aaaaactggg
    14881 ggttaatccc tcaaaataat ttctttctaa attttcatag cttactatcg gttttattaa
    14941 accacgagat gaaaaatatt ttggctgttt atatccactt ggaatagcta gtaaatcttt
    15001 tgtgatatat tttgtaatgt agttagcaac tttttcagaa gaatcgattt ttgtaacagt
    15061 actaaatcct aattgatatg aatcaacatt atagacttgc ttgccattct tatttatcaa
    15121 tcgaccagtt ttagtatttc ttgcttttgt taattttgga ctaaaaccgc ctgttactcc
    15181 atgaaaatga agccgtccat ttttatgtaa ttctggtatg aaaatgtagt gaaattttcc
    15241 atatttttca cgctgagctt tgagccaagt gcgtattttc ttttttacga ttaaataatc
    15301 atgggaattg attttttcgt cgttaaaagt taatgtccaa aataaatcga aatcattgca
    15361 cagcatgtag tgacgaatac gcctttttat cctattggct tgctgataga gttctttttc
    15421 acttggactt ttagaagtat tagatactgt agtatcggtt tctcctagtc ttctaaattt
    15481 tgcttttcga tagtatatga cctcgaaagt atttgaatta tattgaatta tttttgtgtt
    15541 atataattct ctagtcatta gtcctccgct tatcatgcct gcatgtcaag tagcaggcta
    15601 atatacacat ctagcgagtc ctggcttgct tatgagcaag ccggctcact agatagttag
    15661 ttcattctat ctgctttctt ggaatagttt gaaagtccct tattttattt ttgaaatcta
    15721 ttgaatctaa atcaaaatac ggagtctcaa aatattttat tccgtttgtt ttaggagtta
    15781 aaatatatcc ttttccaact cctcctctgt actccgccaa aagatctatt ttctctttac
    15841 ccatgacact gtaaaacgtt tcttcagata tactggaact attccctaaa ataattctag
    15901 tttggcactg ctctgtgact gcacgcggta aatcagaagc aaggagcttt tggcttgcaa
    15961 gaacaagcaa tccctgtcca gaagcccgtg attttaaggc aagtattttt agtagcctaa
    16021 ccatttcttt ttgttgcgct gatgttccac attccaaagc tgccagcact tcatcaaaaa
    16081 ttaaataatg tgcaggtaaa gaaaaatgtt tgtacgtggt cccaaaatca actgaagaaa
    16141 atgcgaaata tcgcttatat ctatcttcca tttcaaatac catttgttct agaagtagaa
    16201 taatctcttc cgcattacgt gcgacaggaa tacctagatt ttcaaatgtc gcacctaaag
    16261 aggtttgttt agcgtcaatt aaacttatag aatgaccttg tttaattagt aacccagcta
    16321 gtgtggctag ataaagtgac ttcccagcac cactaggagc tattataatc tgctgattag
    16381 cctcactagc tatatcaaaa caaatattat cataaagttt tattggctta taattgatat
    16441 aataatcttc atctgttatc ttgaatagtt cactaacagt atatcttgga tttgattttc
    16501 catattttat aacaacgtaa ctattttgca cagttgattc caagatattc cagtcctcgt
    16561 tagtagcttg aataagaaat tcggtcaacc gccttgttat ttcttttact tgctgaatat
    16621 taggaattgt ccctgaagga ttgagttcaa ttataatcct ttcattttct ttataaaatt
    16681 tccattcaac tgtttttatc tgtattttat tagagggaag ttgaattagg tctaaacgtt
    16741 ctgttgcaag tctaagaatg cttaaaaatc tgtacttcca tataggagag taagtagaaa
    16801 ataagaattt tactacaata taccatataa aaatatctaa cagaacagaa gatataacaa
    16861 tacttatctt gtagatagtg cttaataaag gaaaatgtga tgaaagaaag gtaatgataa
    16921 cagatattag gaacaccttt aacagtttct taataagaga gtactgcctt tctttacggc
    16981 tttctatagt ttctgaaaca gataagtaag taggggtata ttcacgacaa tcatatttac
    17041 taagtttcct ttttatttta gatactatca tgatttagca cccgataact ttatttctga
    17101 aataatgagc ttgaattctc ggtacgcacc accatttcga ccatcagata cccattttaa
    17161 cgctaataat gctccttcta aatctattgt tttagcaatg attaactcat tattaatttt
    17221 ttttaaaaaa gattcatcgt tgtatatctc aatagtgaaa ggttttatgc tacttaaatc
    17281 tccaccaacc tcttgaatag ccttaacaat ttctgactga agagccaata aaactttttt
    17341 acttattgtt ccatcaatga cttcattttt ttcattacgt ttaggaacat ctctacattc
    17401 aataacaaaa gcactagtag gagtatgttc tacattggac gtaccaatta gtagattttt
    17461 caagcttggt gagttaaaac tcacttttcc aaaattattt tccatttgtt acctctttat
    17521 ctttgtgtgc acactagatt aatttcatca agcagttcat gacctccttg acagtcatat
    17581 tgtctcattt ttaattagtt gaaatgtggg gataaaaatt ttttgacaac aaaaaaatcc
    17641 ccacgcgaag tggggaaaat atgctataca gtactaaata aaaattttat tatttacgat
    17701 aaattaaact ttcgagtgtt agtttatcta tcattggtaa taaaatatac tttgctaata
    17761 agtctaactt ttctggaagt ttttgatagc taagataaga ttccttattt ttaggtgata
    17821 gtgtgacaga gtcctttttc ctaaataaaa atactgaatc gttttctaaa atttctatag
    17881 tatcaaactg attataggta aaatcaataa atttatcttt taattcattg taagaagaac
    17941 ttgccaaagg aaaatgttgt tgaaagtatt ctttgatatc tcctgtattt gttagtgata
    18001 aattcaataa gtgcttagaa tattctggta ttccttgaat atcaagaatc atttcaataa
    18061 agaaatcttc taaatattcg tctatatcac ggccccataa tacttcattc tcatcattaa
    18121 aataatgttc ttcattaaca aagtaattca atacacttgg agttattaaa tagggattgt
    18181 tcctacttaa atcagataaa ttggagtaat ttaatatttt cccaataagt ttttcatctg
    18241 aatgtaaatc gatatgtctt ttgagtttta aatctttgta tttcttttgg attctttgtg
    18301 aacatttttt aaaaataaaa tgacatgaat taggaaattt ttgcttacat aaattattga
    18361 attgcttact tgacatatat ttaaacttct tctatatcat ctggaatata agtaattaca
    18421 tcatatacat tgcagttcaa aataaaacat agggtatcta atgtagctgt agttattggt
    18481 tttccttttt tcattctatg tagtgtattg ctggatagac cgtggtgaaa aattaattcg
    18541 tactctgttt ttccttgttt aaacaaggtt tcgtagaagg gtttatatga aatcatcgtt
    18601 ctcatctctt ttctaaatag ataatttcat tttatctcta ttaatttgtt gactatactc
    18661 aataaattga ctataattag agggagagta attgattgga ggattttata ttgaaacttg
    18721 aagattttca gacttttcca tttaaaagtg tccaagaata tatttcagac aaagaaaaag
    18781 caataaaatt cagtttctta ttgcaaggag acgaacctga ccgttctgaa ttgatgaaat
    18841 taatatataa agacattttc gaatggtatg atgacaaagt acatagtggc gacactctta
    18901 taacatatcg tacagcaatt tttcgaaaat attatggaaa atcatatagt aagttatcca
    18961 gagataagca acgcgagatt cttaatatta taaaatcata cactgaatat gatgatgatt
    19021 ttcctttcga atttgagctt gacaataaag aaaaaaacgt ttatcagatt tgtaataatt
    19081 atcaaatagg aaattttgga atttttccaa aaggaagaat aaatcctaaa agagcacagt
    19141 ctccttataa tgattatttt gaccttactc tatcagtaat atgggactta tatgatggca
    19201 cattgactcc agatgatgag tttaaaagag caattttaga tgaaaaggaa tattttgacc
    19261 aatttaaaga ttttgaaaca tttctatccg ataacttctt aactgtattt tttgatgatg
    19321 aaggatattt aattcgatta tctgaaattg atgattttga ggaatatgta agaattagta
    19381 atcaaattat ttatactaga gggcttgcta ttctaaccta ccttcaatca atgtatgatg
    19441 ataatagtga attgcctacc caacaacttg aagaaaagaa aacagttcct agaccaacta
    19501 ccaaagagtt agcacatcga actcttaaaa ttgcagaaga agaaatagat aaaatttcta
    19561 aatttgatga atattataat gaacttgaat ttaatcttca taaagaaaaa tttgaaacta
    19621 caaaaaaacg aatatacggt gctattgttc ttttcttgtt cattgtatca ctattttttt
    19681 acacttcaga aattatcatg ttcatttgga ttttatctac agtactatat gtagcagata
    19741 aaatcagaat tgttaaagaa aaaataaaat acgataaaat aataaatgcg actcaagaaa
    19801 aatataggga agaaaagaaa aaattattat ctactttgcg aaaagagtac tactccattc
    19861 caactgaatt tagaacatat aatcatattt caggtataca atatttttta aacgctgata
    19921 ttgcatcaaa tttgcaacaa gctattcact attattcaaa tgaatacaat tctaaaagaa
    19981 tgcaagacca aatttatagc ttacatcatt caaacacaat attacaagat agaattaagg
    20041 agctcgaatt agaaagagag ctggaaaaat actaatcaaa aaggagaata ctacaatgac
    20101 aaaatttaat ttacaatcaa atcaaattta tagtgaatta agtaagtttg agatagaaga
    20161 aatactgtat aatgctacaa aacaattgaa cggtagtgtt gaacggcaaa gttctgaaga
    20221 aatttcatac tctggacagg gaaatttttt tgattacatg aagcacccag gtttaagtag
    20281 atatacatgt tggcaagtct tagttactat atcagattta ggggataaac gaaaagttga
    20341 gctaactgca gtcggagaaa gtccgattag ttacctacta aataattttc tatcattcat
    20401 tactttttat accttattcc aacgtcatcg taatcttaat tttggcatat caaaagaaaa
    20461 ggctaaatac ctttctaatt tgttgtagaa gataatttat atacaaaaaa ctctcttagt
    20521 acatattcac actaagagag ttttttgtaa tctatttgcc aagtttggcg ggaaaattgg
    20581 cggggtaact tttctaaaaa gataaattta taccattcta acttctataa acccgataga
    20641 atcggtgtaa aacattcatt tttactttct atattattcc cactcaactg ttgcaggtgg
    20701 tttacttgta atatcgtaga cgatacggtt aacatgatcc acttcattta cgatacgtac
    20761 agagattttt tgaaggactt cccaaggaat tttggcaaag tcagctgtca taccatcgat
    20821 agaagtgata gcacggattg caatcgtgta gtcatacgta cgaccgtcac ccataacacc
    20881 aactgaacga acgcctgtgt taacagtgaa gtattgccag atatcacggt caagacctgc
    20941 tttagcaatt tcttcacgaa gaatagcatc tgactcacga actgtttcaa gtttttcttc
    21001 agttatttca cccatgacac ggatcgcaag acctggtcct gggaatggtt ggcgccatac
    21061 gatatggtct ggcataccaa gctctgtacc aaggacacga acttcgtctt tataaagagt
    21121 attgagtggt tcaatcaatt caaactgcat gtcttctgga agaccaccca cgttgtggtg
    21181 tgacttgata gtttgagctg tatccgtacc agactcgatc acgtcggtat ataaggtacc
    21241 ttgagcaagg aatttcacat ctttgagctt gcttgcttcg tcatcaaata catagacaaa
    21301 ctcgttaccg ataattttac gtttttgttc agggtcagaa acacctgcaa gtttatcaag
    21361 gaaacgctta gctgcatctg ctttgacgat attcaaacca aacttaccac caagcatgtc
    21421 cataacttgg tctgcttccc ctttacgaag aagaccgtgg tcaacgaaga tacagattaa
    21481 ttgatctcca attgcttttt ggagaagaac tccaacaact gaggagtcaa caccgcctga
    21541 tagaccaaga aggacacgtt tatcaccgac ggtttcacga attttttgga tctgcatatc
    21601 gatgaagtta tccattgacc agtcgccttt agctttacag atgttaaggg caaagttacg
    21661 aagaatatca tttccgtata cagaatgacg aacttctgga tggaattgga taccgtaaat
    21721 atgtttatca gggttttcaa tggctgcgta tgggcagtca gcggatgtac ctgtacgaac
    21781 aaagtcagaa ggaatttcag taactgcatc accatggctc atcaatacag tttgttcatc
    21841 aggtgttgat tcaaaaagag ctgatggtgt atgtgttagg gttgattgac cgtattcacg
    21901 atttccagca tcacctgcag gaacaacttt tcctccaagc ttatgggtca ataactgcat
    21961 accgtaacaa attcccaaaa taggaattcc gagttcgaag atttctgggt caatatcaaa
    22021 tgaaccatct tcatatacag aatttggacc acctgaaagg atgattccta caggattgat
    22081 ttcacgaact tcagcagctg aaattttatg gctttttagt tctgaaaaaa caccaatctc
    22141 acggatacgg cgtgaaatca gctggttgta ctggctacca tagtccaata cgatgatttt
    22201 ttctacatct tgcaaatcag ttgaaatgtt gctcatcttt ttcctttctc aaaagaaata
    22261 tcttttctca atattctatc acaaataagg gcgaattacc aactaaacaa ggcgaagttt
    22321 gactttttct agtttattgg ggtacaatag agaaaagata gaaatgaagt gaaaaatatg
    22381 ctacctgctt atatgaaaat ccatgatcag ataaaaaagg atattgacga gcaccgttgg
    22441 gctattggtg agaggcttcc cagtgaaaga gatttagctg agcagtttgc ggtcagtcgc
    22501 atgaccctcc gccaagccgt atctctatta gtcgaagaag gcgtcttaga gcgccgtgta
    22561 ggaagcggca cctttgtttc cagtactcga gtacaagaaa agatgcgagg gacaaccagt
    22621 tttactgaaa ttgtcaaatc ccaaggtaaa gttccctcta gccagctcat ttcctacaaa
    22681 aaaaccattc ccaatgagca agaagttgcc aagctaggaa tttttccaac ggacaatatt
    22741 atccgaatgg agcgggtccg ctatgccgac caagttcccc tagtttatga agttgcttct
    22801 attcctgaaa aattcattaa ggactttaaa aaagaagaaa tcaccagtca tttcttccaa
    22861 accttgcaaa aacatggcta tcgtatcggc aaatctcaac agaccatcta tgctcgcctt
    22921 gctaaagaaa agattgccca ctatttggaa gttgaaaaag gacatgctat tcttggattg
    22981 actcaggttt cctacctaga agatggtact gcttttgaat acgtaaaaag tcaatatgta
    23041 ggcgaacact ttgaatttta tcttgaaaat aattagatta ccacgcaaaa actctctgtc
    23101 acggacaaag agtctttttt atttttctaa gaataaatct ttcaaaggaa tcaaagttac
    23161 agcaaacaat atcattgcca taccaagaaa atcaatggga taaaattgtt cattcattat
    23221 taagaaggca aagaaaaccg ccgatattgg ctcaattgaa gccaacaagc ttgacttgac
    23281 cggtcctatc agactggctc ctttaaggaa agctgtatag gcaaagacag tcccgataag
    23341 gataatgcct gcaaacgcaa ggagaaaatc aagactagtt gggatatcgg cctgtagaac
    23401 ccctgtaaaa ggaagggcga ccaaacctgc tatgaccatt cccacaccaa tgaccaagct
    23461 gctcccccac tttttaatca aggctatggg taaaatgata tacagagcat aagtcaaggc
    23521 agaaaagaga ccccagaaca ggccagcagg tgtcatggat aactggtcca actgcccatg
    23581 tgttgcgatc aggaaggttc ctccgatggc gaatatgatg gaaactatct ctcccagtgt
    23641 cggtgccacc ctatccttga tacagctata aattaaaatt ccgacaggac aaacatactg
    23701 aagcaccgtc gctgttcccg cattggtctc ctgaatagca gacagatagg cgaattggtt
    23761 gagaaaaaga ccaatcagag caaaaataag aagagacagc aaactctttc tatcctttaa
    23821 aaagaccagt attttatcct ttgcagtagc ataagccaag atcatgagaa ttccaccagc
    23881 gattaaaaga cgcaagttgg tcaagaccag agccgaaatt ccgtgtgcca ttaggtattg
    23941 gccactcgtt cctgacaacc cccaagcaat accagccaca actgttagta aagtcccttt
    24001 taaactattt gacatgtctc tccttactct tctttacgaa tcaagttcat cacttgattg
    24061 cggtctaata tccattgagc tctctcgtcc ttttcatagg tacgattcga taggaaaata
    24121 gtggcttctt gcttctgacg attccacatg ataaaggtac ctgtatagcc cgtatggtct
    24181 agccaatctc cttccaaatt ccatgctaaa gaacgttcct tgtcatccaa aggagaaaaa
    24241 ttttgattta agtctcttgc aaaatcatct gctaaatagt gttctaaaaa gatttgtaaa
    24301 tcctttatag tcgaaaataa accagcactc ccagcatgtc tacccaggag acgagccttg
    24361 ggatcatgca ctatgcctgc ctctacacct ctaactgttg gaacagcaag ctcaactggc
    24421 ccaaccttgg tttccgtcat tccccaaggt ttccagactt gatcctttaa aatcacatcc
    24481 aaatcttgat taaaaattct ttccaaaata aagcccaaca gcaaaaaatg gacatccgaa
    24541 taaagaaagg ctggctgact tcgtctattg agatgaaaca tcgcttcctt taattcaggg
    24601 gctgttaaaa gatcacgatt aggaataaaa ggatcaaggt ctgttgcatg agtcaagagc
    24661 tggcgaatag tgatgtctgg ataatcactc tcaggtaaaa aatctattac cagtctatca
    24721 atatctaatt gacctatttc ccacaagaag gtacaaactg tgccaacccc aacaacctta
    24781 ctgacactag ctaggtcata aactagtcct gcctcagtct gcaagccatg ctctgggtca
    24841 ctctggccta aatagaactc tgtccattga ttgtccttaa aatacgcaaa agaggctccg
    24901 ggataaattc ctgcctcgat ttgttcttct atttttttaa taatcttggt ccacttcata
    24961 cttcttcaaa ccacaattca acattatttc tatctttaca aaggaagaat ttttcagact
    25021 taggaataaa atattcagta gactcaaact tctggcgaag acttgctatg tctaattcat
    25081 tgaccaagaa cttgagcata gataagtccc aggtaaccgt attgtccaca gtcaaatcct
    25141 gcccctgagc tggaataaaa tcaagggatg ccccaatttc agatgattcc aagaaacttt
    25201 cgatatcagt tgggagatgt aattccatag aaatctcaaa tttacttaaa gaaattgata
    25261 ccaaatctgt ttgaaattca ggcttttctc ctacttctac tagacttgct ctgtcatctt
    25321 ccgcatgaat caaaatcaaa tcatcttctg gtgagaaaat ttcaaaagcg tagccatttt
    25381 gacctttata taatcgatga atcgaatctg ttttagataa gattccttca atttctaagg
    25441 gattttccac cttgacaatc aatctagcta gtttttttct tccctctacc ttacgagtac
    25501 gcatactggg agcttcttct aaaaccagct tttcaagacc cgtttggtca cctagtgaca
    25561 gaaaggccga ttcttctagc aaggccttca ttccaagggt ttcaatataa aatgtttcat
    25621 ttaattttct attattagct tttaaagtag gaataatccg tacaatctga tttacattca
    25681 taaattcctc cgtcactttt tattttaaag gattttagaa ttttttacaa gatattatgc
    25741 tcaaatttaa cattatttag ctatttagta aagatagtct ttcaaggctt ttgacaaagc
    25801 ctgataacca gcaatactga ggtgcagtcc atcagttgta tattcttttt tgagttggcc
    25861 tgcttggtct gtcaaacaat caaatactgg cacaaattcc atctgcatat aggcagatgc
    25921 aagctcttga taggcttgat tccaattctg aattttttca ttcgagcgga tatagactgc
    25981 ctgctggtac ttctctccct cattgacagg caaaatggaa agcaatttaa tctctgtcaa
    26041 tggataatcg cgagcaacgg attgaatgat agcttcgaga ttattgagag cctcattcac
    26101 aggaacatcc tttccgatat catttgtccc aatcagaaga aaaattttat ctactgctcc
    26161 accatgtaga tgagcatcaa ggttctctag taacagtcct gtctgatagc cacgaattcc
    26221 tcgattgaca atcgtctttg aagtcccaaa tagctcctgt agaggataat actcgacaat
    26281 ggaatcccca ataaaaagaa tgtttggttc tacaacagaa atgtgattta ggtgacgata
    26341 cttggtttga attttttctt gttcctttag gagccaattt tctaataact gtactgccac
    26401 ttcattctcc tttttctaac cagttttcca agacttgata aactcctcct tggctgttgg
    26461 ctggtgctag agcagtcgcc acagctttgg ctttctcatc agcattttcc atcgcatagg
    26521 caattccagc catttcaagc atttcaacat cattttcact atcaccaaaa gccatgattt
    26581 cttgggattt caagtcccag cgcttgagta attcctccaa gccccatgct ttatgaatcc
    26641 cagcttggag gatatcaatg caaccatagc cactggatac agctcggaca cggccatcaa
    26701 agagagcatt gatttcttcc aaaaccgaac tcaaacgttc ctcaccaaca accatgctca
    26761 tcttgagcac accaccaaag aggtcagatg ttaattcatc cacaaattgc atccgtttgt
    26821 agaatttttc aatcatttct ggagtcataa aactttcaag atctgtaaaa atcgtacctt
    26881 ccttgacaaa atcacccttc atccccgtta caacaaactg gtcctgacac gctcgaccct
    26941 tgaaatgagc caaagccttg ttgacaatgg cgtcatccca tgtcttagcc tgaatcaatt
    27001 cattgttttc aaaaatacga gcgccattag caacaaccag aaccactcga tccaccaagg
    27061 gactcagtag ttgtctcatg cggtgaattt cattgcccgt cgcaatgaca aaacgaatgc
    27121 ccctttgatc caactgatct aaaatctttt ccaatcgtgg gagatcaagc tgacctctag
    27181 catccagcaa ggtcccatcc atatctgtcg caattacctt aatcatcatt tactttcctc
    27241 tggattcaag ctaataccac ttcaatccca catgttcatt catttcttta taggctgtat
    27301 caattcgttc cttagtcgct tcatctaact ggtcacgatg actgccaccc tctataaaat
    27361 cttccaaaat ataagtttgg taatgataca agggatatcc ttctggtgaa aaggttccct
    27421 ttggtgttcg attgacccaa gtaggatgag ctttagctgt tccgatagtt gtttttacat
    27481 ccttcttctt gatggtgaca tccatgagaa caccacgttc agtccactta gcattctctt
    27541 catctcccat agattcaatt cgttgattgg aaatgaagtt ccccattgaa tagataatga
    27601 gcttcttatc tccatctttt tcaaccgttt cagatggttc aacaacgtga ggatgccctc
    27661 caaagataat atccgctccc caatcgatca tcttgtgata aagagctttt tgttcttcag
    27721 ttggttccaa tcgatactca acacccatct gaggcatgat aatggtgata tctgcttcct
    27781 tctctgcccg ttcaacttca gcctttatct tatcttctct tcgtttaaat ctgaaagata
    27841 acgattatag tcttcctgag aaatatactg ctcaattcca ttgaaaccat aggaataggc
    27901 taacaatgca accttgatac cattcacttc cttaatgacc agcggagcct gatcacgtgg
    27961 ttcgtgcgta taaactccga ttggaatgat tccagctttc tcaataatat cggccgttga
    28021 aataactccc tcaatttgcg aatccaaaat atgattatga gctaaatcca gcacatgata
    28081 acctgcctcc ttaatagcat ccataacttc agcaggagca ttaaagagag gataacccgc
    28141 taaataatga tccttattaa tggttccttc aaaatcacca atagctaaat ctgcttgctt
    28201 gagccaagga gtcacatact caaaattttc atgaaagtca taggtaccgt cttctttttt
    28261 agctgaaaag aaaagtccat cgtggtagag caaatccccg tgtgccataa ttctggcagt
    28321 tttttcctct tcctactcct gagacttttg cttagtcccc tcttgagaaa tagtatctcg
    28381 tttttgacta gtcaagggat tccttggaag ctttcaaaca acaagaccaa gcccattgat
    28441 aaaccaactg ctagcaagag tatcgccaca aatcccttat tgctccaatt gcgataactc
    28501 ctaaaaagtt taccaagccc ttcataaaac gaaaagctaa accaccctga tttcgatttt
    28561 gtcttctttg catcttcatt ctccctactt tcttatgcaa gccttttctt tttattatat
    28621 cacagataag tatttctttc acaattgaat tgaacttcct atctattttc tataaatcct
    28681 aaatgccata atgctttcaa tccttgtcat tttgtgatat catgtagagg taatgaaagg
    28741 aaatgaacta atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta
    28801 actgcactaa acataatata aggagagaaa atgtctgcaa tagaacgtat tacaaaagct
    28861 gctcacttaa ttgatatgaa cgatattatc cgtgaaggga atcctactct acgcgcgatt
    28921 gctgaggaag tcactttccc cctatctgac caggaaatca tcctaggcga aaagatgatg
    28981 caattcctta aacattccca agatcctgtc atggctgaaa aaatgggact ccgcggtggt
    29041 gttggactgg ctgctcccca gttagatatc tcaaaacgca ttatcgctgt tttggtacct
    29101 aatattgttg aagaaggcga aactccacag gaagcctacg atttggaagc cattatgtac
    29161 aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc ttggcgaagg agaaggttgc
    29221 ctgtctgttg accgtaacgt gcctggctat gttgttcgcc atgcccgcgt tactgttgac
    29281 tactttgaca aagatggaga aaaacaccgt atcaaactca aaggctacaa ctccattgtt
    29341 gttcagcatg aaattgacca cattaacggt atcatgtttt acgatcgcat caatgaaaaa
    29401 gacccatttg cagttaaaga tggtttactg attcttgaat aaagaaaatc ccgttgcaaa
    29461 gacggggttt tgtgttataa tagaggcatg aaaacaaatg atattgtcta tggcgtccac
    29521 gccgttaccg aagccctcct tgcaaataca ggaaacaaac tctacctcca agaagatctc
    29581 cgaggtaaga atcttgagaa agtcaaggaa ctagctacag aaaagaaggt gtccatttct
    29641 tggatatcaa aaaaatctct ctctgagatg actgaaggtc ctgttcatca aggttttgtt
    29701 ctacgagtgt ctgaatttgc ctatagcgag ctagattgca tccttgcaaa aacacgccaa
    29761 gaagaaaatc cacttctatt gattctagat ggtctaaccg atccccataa tctgggttct
    29821 atcttgcgaa cagccgatgc gaccaatgtt tcaggtgtca tcattcccaa gcaccgtgct
    29881 gtcggagtaa ctcctgtcgt tgccaaaaca gccacaggtg ctattgaaca cgttccaatt
    29941 gcccgagtga ccaacctcag tcaaacctta gataaactca aggatgaagg cttctggacc
    30001 tttggaacgg atatgaacgg tactccttgc cacaagtgga atacaaaagg gaaaatcgcc
    30061 ctcatcattg gaaatgaagg aaaaggtatc tctagcaaca taaaaaaaca ggtcgatgag
    30121 atgattacca ttccgatgaa tggacatgtt caaagcctca atgccagtgt tgctgcggca
    30181 attctcatgt acgaagtttt ccgaaataga ctataaaaaa gtttccagtc atctgattgg
    30241 aaactttttt atgattaact atgttctgta atgaatttat aggcttcttg accagcgata
    30301 gctccatctc caaccgctgt tgttacttgg cgaaggtctt tcaagcgaac atctccaact
    30361 gcaaagatac cgtcgactgc agttttcatg tggttatccg tcacaatcca tcctgcctga
    30421 tcttggatat tcaattcttt aacaaaatcg ctaagagggt ccaatccaac atagataaag
    30481 acaccaccga aggcttgttc tgtcacttga cctgttttca cattttcaaa tacgactgat
    30541 tctactcggt tttcaccctt gatttccctt actacagaat cccagataaa gctgattttt
    30601 tcattcgcaa aggcgcgatc ttgtaaaacc ttttgggcac gaagttggtc acgacggtga
    30661 acaatggtaa cagtcttagc aaaacgagtc aagaagagtg cttcttcaac agctgaatct
    30721 ccaccaccaa ctaccaataa atcttggtca cggaagaaag caccatcaca cacagcacag
    30781 taagaaacac cacgactgtt cagttcttct tctccaggca ctcccaaagg acggtgttta
    30841 gaaccagttg ctacgataac ggtacgtgtt tcatatgttt ggtcatcagt catcactttc
    30901 ttaaaatcac catggtcttc gacattttca acataaccat aaatgtgctc aacaccaaga
    30961 ttttcaagtg gttcaaacat cttttcagcc aattcaggtc cactaatatt agcgtatcct
    31021 gggtaatttt cgatatcaga tgtattattc atctgaccac ctggcagacc accttcaatc
    31081 aaagctactt ttagattgct tcgagcagca tacaaggccg cagtcatccc tgcaggtcca
    31141 gcaccgataa taatagtatc gtacatatag attccttctt tcttgttgta actatcttta
    31201 ttctaactct ttcttgtcaa tcacgcaagg attatgcctt gaaaacaaga attaaactca
    31261 taaccgcaaa ggataatact gggacaacca agactccaat cataatcata tcatagagat
    31321 gggcttggcg agccttggct gtcttatcaa ctcccgacat ggctctcaga ccaatccaaa
    31381 tccctaaaaa aatcagaaca aggatggtgg tcaagatcaa actctcgaaa tataaagaaa
    31441 atagttgcag tagcatgatt tctctcattt ctatcttttt taaagagtaa actcagctag
    31501 tccaactaac tgagttttcc tttatctatt atatcaaata taagtccgtt tgtaactagc
    31561 gaagaattct tttgtccgct cttctttagg ggtgtggata atctcatccg gtgttccaga
    31621 ctcgatgatt ttccccttat ctaagaagag aatcttatca gccacttggg ctacaaagga
    31681 catgtcatga ctaaccaaaa tcatggtttg acctgactta gcagcatctg caatagactt
    31741 ttctacttca ccaaccaatt ctgggtcaag ggctgaagtt ggttcgtcta agagcaaaac
    31801 atctggtttc atagcaagcg cacgcgctag ggcaacccgt tgcttctgtc cacctgataa
    31861 atggcgagga taatggtttt cacggtccga aagcccaacc ttagccaact cttccttggc
    31921 aatcttagtc gcttcttggt cagataattt cttgacaaca accaagcctt ctttcacatt
    31981 atcaagtgct gttcggcgtt caaacaaatt aaactgttgg aaaaccatag acaacttacg
    32041 acgtagggca aggatttctt cttgagtgat tttagaaaaa tcaactgaaa aaccatcaat
    32101 ctgaatagag ccactgtcag gtgtttcaag ataattgaga ctgcgaagaa aggttgattt
    32161 tccagctcct gaagaaccaa tcaaggctac aacttcccct ttttgaatat ccaagtccag
    32221 atgatccaag acagtctgtc ctgaaaagga tttgcttaaa ttcgaaatct taatcattaa
    32281 cgaaggtctc ctttcacatc tgtttgcact gtatcaggtg cagaaatatc catttttctc
    32341 tcgatgaaac gaccgaggct ttcaattccg atattgacca cccaataaac aagggcaacg
    32401 gagatgaagc gttcaaaata gcgataatca gctccaccta gaatctgagc ttgggcaaag
    32461 acttccacaa cacccgcact aaaagctaga gatgttccct tggtcaaacc gatgagggaa
    32521 ttaatcaagg ttggagtagc taccaccgct gcattaggaa taatcactcg tcgataaact
    32581 tgcgctcggg tcatacccag actgcgtgcc gcctcaatct caccaggatt aactgagaga
    32641 atggctgcac gaatggtttc actagcataa gctgcctcat taaaggcaaa ggcgacaatc
    32701 gcaaaagctg cagctggaat cgcattgata ttgagaccag ttccccattg ctgattgagg
    32761 gctttcaaag ccaaagggat tccgtagtag gtcaacatga gttgcaccaa aatcggtgtc
    32821 ccttttaaga aactaacaaa gaaggcctgc aagggatata aaatcttgac acgattgatc
    32881 ttcacaatgg caaaaagaag cgccaaaacc aagccaaaaa gggcaccacc aattgtcaac
    32941 ataattgttg ttggaagttg ttggacaatt ctagggattc catcaaagac cgaacgtagg
    33001 ctaaacagct tgccatccgg aatcaattgc atcaagtttt ggtaccaatc tgatgctaaa
    33061 atcgttgtaa cattcataaa aacatcctct tctgataatg attcattcta ccatgcttct
    33121 gccgtcaatg aaattatttg ctacggtcag atacagactt tgtctaccta ctagtttatc
    33181 atactttgaa acagggaagt tatatatttt atctatcaaa gagatagata aaaactattt
    33241 cagtcccagt tcttcataag attttcgata accgatttgc ttaacagttc cattttctac
    33301 taaaatgggc cgttttaaca acataccgtc acttgctagc aactcagccg cttctcggtt
    33361 tgacaaactt cctaccttat cttttagccc taattcacgg tatttgatac cactggtgtt
    33421 gaaaaattgc ttcaattcaa atcctgaggt ttctagccaa ttcaaaatga cttcttggct
    33481 aggtgtttct tccacgatat ggacggcttt atagtccaca cctaattgat ttaattcttg
    33541 ttttgctttt ttacaagttg aacatttggg gtattcgata aattctaaca tgtgcttctc
    33601 cttctattgt ttctatcttt aaaatctact ccttcatgct ccaagagcca agctttcttt
    33661 tccactcctg cagcataacc tgtcagacgc ttgcctgctc ccaacacacg atgacaaggt
    33721 actaggatag accaaggatt gcgtcccact gctccaccaa ttgcttgagc agaagccact
    33781 tgcaggtctt gagcaatttg tccataggtc actgtctgac cataaggaat gccctgtaaa
    33841 tagtcccaaa ctctcttttc aaaattcgtt ccgattggcg ccaagagcaa gttggataaa
    33901 tcctgaggct cgcctttaaa gtaatcatct aagcaagcaa taactgggtc taaaatagga
    33961 tgactaacaa cttcttctat cgtttcatct cctagtcccc tctcaaaatg cttctgctcc
    34021 tgaacccaaa ttccatacaa ataatggtca tcagctacaa gtgatagaat accaattggt
    34081 gaggagtaga gtatttttac atacttcttt tgcattattt ctttaatttt tgataggcca
    34141 agcgttcgcc atctactggc accttaccaa cttgtttaaa accaagtttt tcaaaaatat
    34201 gttgcataac cttgttttca gcatgcgtat ctgagcgaaa atcaagataa tcaaaacctt
    34261 caatcaagcc ctctaagaag gtttgagcaa ctccttttcc ctgcacatct gctgccacag
    34321 caatacggtg aaagactaga tactctgact ctccagcttg ccagtttccc tcataaatag
    34381 cttcataggc ctcctctgga ctcttggtca cagcagcata ggctagcagt tctccctctt
    34441 ccaaggctac gtaggcttgc cctgagatga tatcatcgat aataacatct gcatttggat
    34501 agccattttg ccactggtca ctaccagcat ctgctaaaca ttttttggca tcctccatca
    34561 cctgcatgat ggcatctact tcatttggaa aagctaaacg aatttccatc ttttttcctc
    34621 atttctgact agtttctccc atcatagcat aatttaagta tttctacaag cagttaaaac
    34681 ttgactttgt gtttttgtta ttttataatc tagttatcaa aactatataa aaaggagttg
    34741 aaaatgaaaa ctaccttttc ctacccaaaa tgggcagaaa ttccaaacat tgacctctat
    34801 ctggaccagg ttttgctcta tatcaatcag gtctgcgccc ctatctctcc taataaagac
    34861 aagggcctaa cagcatctat ggtcaacaat tatgtgaaaa atggttacct gacaaagcct
    34921 gacaaaaaaa aataccaacg ccaacagatt gcccgtttga ttgctatcac aaccctcaag
    34981 tctgtatttt ctattcaaga aatagcccag acacttaata ctctacaaac tcaagcaagt
    35041 tcagaccaac tctacgatgc ttttgtggac tacatgaacc aaggaattga cccagctaac
    35101 cctattatcc aaaccagctg ccaaaccgtt aaactctatc atcaaactct agacttaatc
    35161 gatcatactc aagaggaggt aatccaatga acactagtct taaactcagc aaacaactca
    35221 gttttggaga ggagattgct aatagcgtga cccatgctgt gggtgcagtc atcatgctta
    35281 tcttgctgcc tatttcatcc atctatagtt atgaagcaca cggattttta tcctctatcg
    35341 gcgtttccat tttcgtcatc agtctctttc tcatgttcct atcatccacc atttatcact
    35401 ctatggccta tggttcgacc cacaaatatg ttttgcgaat cattgaccat tctatgattt
    35461 acgttgccat tgccggctca tacacgcccg ttgtcttgac cttgatgaat aactggtttg
    35521 gctatctgat tattgtcatc caatggggaa cgaccatctt tggtattctc tataaaatct
    35581 ttgctaaaaa ggtcaatgag aaatttagcc ttgctcttta cctgattatg ggctggttgg
    35641 ttctggctat cattcctgcc attatcagtc aaacgacacc cgttttctgg agtctcatga
    35701 taactggcgg actctgttat acagttggag ctggatttta tgccaagaaa aaaccttatt
    35761 tccacatgat ttggcatctc tttatcctag ctgcgtccgc actccaatac atcgctattg
    35821 tttattacat gtaaaaaagt tgagaagttc aatctcaact tttttcttta cacatattga
    35881 taaagtactg gtgcaagcgc acatcatcag tcaattctgg atgaaaagaa cttaccaaca
    35941 tatttttttc ttgggctgca acaatttgat tgttcactgt tgctaaaatt tctacaccct
    36001 caccaacact actgataatc ggaccacgga taaaggtcat tggaatcttg ccaactccct
    36061 tacattctgc ttccgtgtag aaacttccta attggcgccc ataagcatta cgctcgacca
    36121 ccatatccat agttcctaga tgactctctt tctgagaagt gatttcctta gccagcaaaa
    36181 ttaagcccgc acaggtccca aacactggta agccagatag aatggcttct cggatgggaa
    36241 gtagcatgtt ctggtcacgt aagagcttgc ccatggttgt agactcacca ccaggcaaaa
    36301 tcaaacccga caagtcactc tgatcttgct gaaaatcatc tagatttctg agttctacac
    36361 tctcgacacc taattgatct agcacttttg catgttctgc aaaggcccct tgcaaggcca
    36421 atattccgat tttcatctat tttcctcgtt cagccatgag aatttggatt tcattttcat
    36481 taataccaac catggcttct cctaaatctt cagagatttg agctaggatt tgaggattac
    36541 ggaagttagt cacagcctta acaatggcac tcgctcgttt aacaggatct cctgacttga
    36601 aaatacctga accgacaaag accccctctg cccctaattg catcattaac gcagcatctg
    36661 ctggcgttgc aacacctcca gcagcgaaat ttacaactgg caattttcca tgttcatgaa
    36721 catattggac caattctaca gggacttgca aatccttggc agcaacataa agctcgtcct
    36781 tacgtaagtt ttgaatgcgg cgaatttcct gattcatcat acgcatatga cgaacagctt
    36841 ggacgatatc ccctgtccct ggttctcctt tggtacgaat catggaagcg ccttcagcga
    36901 tacgacgcaa ggcttcaccc aaatccttag caccacagac aaaaggaact tggaattctt
    36961 tcttgtccac atggaaacgg tcatcagctg gagatagaac ttcactctcg tcgatataat
    37021 caatttcaat agcctctaaa atctgagctt caacaaaatg cccgattctg accttagcca
    37081 ttactggaat actaaccgct tcttggattt ccttaatcat ctttgggtcg ctcatgcggg
    37141 aaactcctcc agctgcacga atatcagccg gaattcgttc caaggccatc acagctgccg
    37201 caccagcagc ttctgcgata cgagcctgtt caggattctg cacatccata ataacaccac
    37261 ccttgagcat ctgtgccaag tttttattta gttcataacg attttcagtc atttgtttta
    37321 tcctcatcat ttgtattggt tgctaccttt tcattttaag tcagaacaga atgaagcaca
    37381 agataaaaaa actataattg tatggggaca gattggctaa aaactatctg accttaactt
    37441 aaggccagat agctcattca tttttatttt tcagccgtaa gggcagccat tgtgatgtag
    37501 ttgtatggtt tattgaagtg tggcaagaag aagaggtctg tcaatgccaa tttatcaatt
    37561 gtcacatgct cttggatagc aagtgagaac atgtggattc ccatgctaat tgcaatatca
    37621 tgtgaaacca tttgggcacc aagaatttca cggctatctt tgtcaaagac aatcttaatt
    37681 gctacttcat ggttgtcatg tttcatgaat tctggttttt gaagatcgtt aaagcctgtt
    37741 tcagttgcgt tgtaaccagc agctttcgct ttttcaagag tcaaaccagt tgaaaccatg
    37801 tgaagaccgt agattgagat accatttgaa ccttgaacac cgattccttc caattcatgt
    37861 ccacaagcgt tgtaggcacc aacgatacca gtgcgaacag catttgaagc aagagcgata
    37921 tagcttgtat ctttacgagc attgtcataa acagtcgcac agtcaccaac agcgtaaacg
    37981 cctgggatag atgtttcttg tttcttgtct acaaggaagg caccgttgcg gaagagttcg
    38041 atcttaccat cagcaagggc tgtgtttgga cggaaaccaa ctgcaaggat aaccatatcc
    38101 acgtcaaagc tttctttgtc agtaatcaag cgttcaactt taccatcacc ttcgattgct
    38161 ttaacagttt gacctagagc caagcggatg ttgtgatctt ccaagttttt cgccatcatt
    38221 tgtgtgaagt ctttgtcata gtaaccgttc aagacagtat caacgatatc aacaaggaca
    38281 acttcttttc caagacgttc aaaggcttca gcaagttcaa caccgatgta accaccacca
    38341 acaacggcga tacggtcgag atgttggctc ttgtcagaaa gtttattgat aacttcttca
    38401 gcattttggt acaatttcac gaattgtacg ttttcaagag ttgctttaaa ttcgcggttt
    38461 cctttaacaa tttcaacacc ttcgattggt ggcaagattg gtgtagaacc tgtagcgaaa
    38521 atcaatttct cgtatgattc tttgtgttct tttccttcaa cttctgctgt aaccactttg
    38581 ttatcatagt cgattgaaag aactggtgaa ttcatataaa ccttagcacc tttagcttct
    38641 aatttgtctt tatcagaata gaacaagcct tcagcaccgt caatttgttc accaatccaa
    38701 agagccattc cacatcctag gaaagagatg ttagagtttt ggtcaaatac aacaatttcg
    38761 ttctcatttc caaaattatc caacatggta ttgatacatg ctgtaccagc gtggttagca
    38821 ccgactacaa cgattttact cataaaaaat ttcctgcctt cattctaaat ttaccttact
    38881 agtataccat ttaccgttag cgtttacaag gggggtacta ttatttcagc attttttatc
    38941 aaaaataatt ccccatttat cctgttttca agcctcatga attttatgag catatttctt
    39001 gactttttcc aaattttgtt tgtgaaaatt ctaactttat ggtattctaa taacatgaaa
    39061 ataaaatgta agggcttcaa tttagataat tattttatat tacaacttat tttctataag
    39121 agaaaggagt tggtagcttg actcttcgtt cacattctga acggctaatg gggactacta
    39181 tcactatttc attagtggat gaacaagccg atatctttct ccaaaaatcc tttgacttgc
    39241 tcaaagagct tgaataccgc ttcaacgcca atagtcaaga atctgagttg atggaaatca
    39301 attatcaagc aggaatatcc cccgtcacgg ttcatccaga cctgtttgag ctgatttcac
    39361 ttgggttaga gcatagccta gcgctctcta gccacctcaa tatcagcatt ggtcccttaa
    39421 ttcaaacctg gcgtatcggt ttttcagatg ccaaggtcgc ccagcctcaa gaaattgaat
    39481 cggtgctgcc tctaatcaat cctcatggta tcgagttaga ttcttctact tctactgtgt
    39541 ttttaaaaca gaaaggaatg aagatcgatc taggttgttt agccaaagga tacagtgcgg
    39601 ataaggttgc ccaatttctt aggaaagagg gggtgacttc tgccttgatc aatctgggag
    39661 ggaatatcct gaccattgga aaaaatcagg caagagggga taacccatgg caaatcggga
    39721 ttcaagaccc agccaatcct aggggaaatc atttaatgac catccctgtt gtcaataaat
    39781 ctgtcgtgac ttcaggcatt tatgaacgtc acctgaccgt cgatggacaa gattaccatc
    39841 acatttttga cagtcaaaca ggatatcctg ttgaaacgga actagcgagt ctaacaatca
    39901 tctctgataa atcagtcgat ggcgaaatct ggacgactcg actctttgga gaaagacctg
    39961 cttctatcct ctggcaagtc gaaagtttgg agggcatcga agtcatcctc atcgataaag
    40021 aaggccacct aagctgttct tcaggaattc ctactctata gagacaactg tttcaatgga
    40081 attttaaaat tgtattatgt aaaaagagaa aggaaatctc atgttaaaac ttattgctat
    40141 tgttggaaca aattcaaaac gttctacaaa ccgtcaattg cttcaataca tgcaaaaaca
    40201 ctttgctgac aaagctgaaa ttgaacttgt tgaaatcaag gccattcctg tcttcaacaa
    40261 accagctgac aagcaagtac ctgctgaaat attggaaatt gctgctaaaa tcgaagaggc
    40321 agatggcgtt attatcggta ctcctgagta tgatcactct attccagctg ttttgatgag
    40381 cgctcttgct tggttgtctt atggtattta cccacttttg aacaaaccaa tcatgattac
    40441 aggtgcttct tacggtacgc ttggttcatc tcgtgcccaa ttgcaacttc gtcaaatctt
    40501 gaatgctcct gaaatcaagg caaatgttct tccagatgaa ttcttgctct cacactctct
    40561 tcaagcattt aacccaagtg gcgacttggt tgaccttgat gttatcaaga aattggatgt
    40621 catctttgat gacttccgta tctttgtaaa aatcacagaa aaattacgta atgcacaaga
    40681 attgcttcgc aaagatgcag aagaatttaa ctgggaaaat ttgtaagata ggagaccgaa
    40741 agaatgaaat ttgttggact tgttggatca aactacgatc aatcatataa ccgcaaactc
    40801 ttggaattta tccgtcgcaa tttcaaattc aaatttgaat tagaagtact tgaaatcgac
    40861 gaagttccaa tgtttaacca agacgaaaaa tgggacgaaa gcttccaatt gcgtttcttg
    40921 tataacaaga ttacacgtgc tgatggtgtc attatcgcca ctcctgagca caaccacact
    40981 atctcagctt cactcaaatc tgtacttgaa tggctttcat acgaagttca tccatttgaa
    41041 aacaagcctg ttatgattgt gggtgcatca tactatgacc aaggaacatc acgtgctcaa
    41101 gttcaccttc gtaaaatcct tgatgctcca ggtgttaatg cctacacgct tccaggtaac
    41161 gaattccttc ttggtaaagc taaggaagct tttgataaca acggaaatat caccaacgaa
    41221 ggcactgtta aattccttga aacttgctta gataactttg ttaaatacgt aggagtcgtt
    41281 tcgaaattga aaaaaccaaa accaatcgaa tcagaagact tggattgtgg aaaaccaatc
    41341 gctacaacca tcacagaagt tgaccctgac gatccagaat gggtagaaaa agttgcagca
    41401 atcactggtg ctgtttctgg tgatacctat gtcaaattgg accacggtat cctaacagtt
    41461 aaccaaattg atatgttctt gaaagctatg ccatttgaat tgacatacgc tgacgacaac
    41521 aaccaattcc tctactacaa caacgctcac caagatccag acactatgtt cgctaaacgt
    41581 gtaccacctc aatcaggtag ccgtatgtcg actgttcatg gttctcttcc accagcacgt
    41641 atgaagaacg tagagtgggt tatcggaaca cttcgcaacg gaaaccaaga atacgtccgt
    41701 acgatcgttc caggttctcc tgcaggtgtt atcaacactc acaactacca agcaatgtac
    41761 tatcctgatg gatcatacgc tggtatcaat gaaatcgtct ttaacttcca accatggctt
    41821 gactggtacc taaaagagac tggtcaacgt ttggtgggtg gtagcggacc atttgctcct
    41881 gctgccggag gtcatggaga cgccgatgct acttctggcg cttctgattc aggggatgct
    41941 ggaggccacg gtggtgacgc agacgctaca gccggtgcaa gttactaatg atagttttta
    42001 ggaaccatta tggttccttt tttagcgaaa aaagactagc aaacacaaac tgctagtctc
    42061 tttgttatcg tttcatctat ctttgttaaa agaaagaata catattatga atttgggtca
    42121 tcaagactac ggccatgtaa tcctttttca cgttgtactt ggcgtagttt ttctggtgta
    42181 acatcgtttc cttcttcgtc cacaattttg attccttcaa tgtggtgacg aacaacgcga
    42241 cgataacctt cgatgtactc ctcacgtagt ttggcttgtt ccactttttc ttctggtgtt
    42301 aagccttctg tttttttctt tttagcaagc tcattgatac gagcaatttt tttcggatcc
    42361 atttcttctc ctctgtaata agataaagtc cgtttatcaa attttattta gtgttaattt
    42421 ggttaaaaca agcaaactta gctgctttct tggttagttg tgacaagatt gccaaacgat
    42481 tttgacggac agcctgatct tcagccatta ccatagtatt ttcaaagaaa gcatcaatga
    42541 ctgggctaag cgcaaagagt tgtttcaatt gctgacttgc aggtcctgat aaaacgagtg
    42601 tttctactgc ttctgccaaa gctttttctt ggtcattctc aaatagtgct gaatcaactg
    42661 tagcaacccc ttctgccttc tcagccaggt taaaggcacg agaaagtgat tcaacagatg
    42721 gtttaaaatc ttcttccttg cttacttcta cgagagcact tgctgcttcc aacatatctg
    42781 ccacaacaaa gtttgaacct gcaagaactg cttccttgat atcttttaga gtagagccca
    42841 tcatcttatc aacacgagcc ttgataaagt ccataacctc tgctttattt tcataagtca
    42901 aactgtcaaa tttcaatgca taaaggctat caatcagctc atccatagca atgtgccaac
    42961 caaaggcatc caagatacga accacacctt gggtcgcgcg acgaagggca tacgggtcat
    43021 tagaacctga tggaatcaaa cctactgaga agaaactcaa aatcgtatcc aatttatctg
    43081 caatagcaag cactgcacca accttgctct ctggaagttc tccttcagct gatgtaggca
    43141 tgtagtgttc acgaatagca gctgctaccg ctggagtttc accagcaaga agggcatatt
    43201 tttcacccat aattccttgg agttcgtcaa attcaccaac catacctgtc aacaagtcaa
    43261 acttgtaaat ggctgctgca cgagcaaggt caactgtttc atccactgac aaaccagctt
    43321 tttctgccaa aagtacagtg atttgacccg tacgaatcat gtgttcacga agggaaccaa
    43381 tcttctcatg gaaggtgaca ttgtttaatt tttcaacaag atctgaaatc accaattttt
    43441 ggtcttcacg ccagaagaat tctccgtctt ccaagcgggc taccaagact ttttcatttc
    43501 ctttgatgac atttttcaaa cgctctgcgt ttccgttacg aacagaaatg aagtttggca
    43561 agagttttcc atcttgatca cgaacaacaa agtaacgctg gtgttccttc atagaagtca
    43621 ccaagacttc ttctggaact tcaaggtatt tagcatcaaa acttcccatg aaggcagttg
    43681 ggtattcaac caaattcaag acttcattca gcaaatccgc atcaatttcg atacgtacac
    43741 catgttttgc ctcaattttc ttgatttggt caacaatcat ttgctcacgt tcacatggat
    43801 ctgcgattac aaactgctta cgaaggtctt cttcatagct caaggctgac tgaattttag
    43861 tttctttccc caagaaacga tggccacggc tcacacgacc tcccttgata tcaaggaaat
    43921 ccaagtcaaa ctcttgctca tccaagagaa cagttaaagt gtgaacaggg cggatgtatt
    43981 caaagctatt tccagcccag tgcatgctga cagggaaagt caatgacttc aagacatcta
    44041 caacaccagg aacaatggcc tcaactgctt gaccaacttc ttccttagtg acatagacat
    44101 attcttcacc cttgatttca cggaattcga tatcttcaac agtcaagcct tttccacgga
    44161 caaatccttg agctgctttg gtgaagtttc catcactatc caaggcaatt ttctttgctg
    44221 gtcccttgaa atcttctgtc aaatcagact gtttgtctga taaaccagtc acacgaacag
    44281 ccaaacgacg tggtgttgag aaggtttgaa tggcttcaaa agacaggcgg ttttccttga
    44341 ggaaggctgc cattttttcg cctagttgtt tttcacttgg tgtgacaaca taggctggta
    44401 attcttcaag accgagttct actaataagt tttttgtcat gttttctcct ttacattttc
    44461 ttcaatcttt tttgatatgc accttaggta ctggggacgt cgctaactaa ctctgtgagt
    44521 ctgtatggaa atccaatgct aaatttatca agatttccaa caatctcatc aaagtggatt
    44581 tagctgactg atttttgaac ctaaggtttc aaaaatcccc acataacagt acggcggtgc
    44641 atatccctct agcaagtctt cgacttgcct ctaacgattt tagagtacag tattactcac
    44701 tattctgcgt cttctgctaa aagtttaact cgtgtttctt catccaaaag tgggtaacct
    44761 aggcgtttgc gttctgcaac aaaggttttg gctacaacac gggccaagtt acggatacga
    44821 gcgatatagc ctgcacgctc tgttacagat acggcaccac gcgcgtcaag cagattaaag
    44881 gtatgtgaac atttgagaac atagtcatag gcagggtgta ccaagccttc ttctaatgca
    44941 cgaccagctt ctttttcaaa cttatcaaag ttttcaagca acatttcttg gtccgaaatt
    45001 tcaaatgaat attttgagtg ctcatactca ggctggataa agatttctcc gtattttaca
    45061 ccatcagccc actcgatatc atagacagag tctacttctt gaatgtaaga agccaagcgc
    45121 tccaaaccat aggtaacttc cgcagtcaca gggccagttg ccaatccacc gacttgttgg
    45181 aaataagtga actgagtgat ttccattccg tcaagccaaa cttcccaacc aagaccagct
    45241 gaaccagttg atgggttttc ccagttgtcc tcaacaaaac gaatatcgtg ctccaaagga
    45301 ttgattccca atttttccaa agactcaagg taaagttctt ggatatttga tggagaaggc
    45361 ttcatgacca cctggaattg gtggtgttgg tagagacggt tagggttttc cccataacga
    45421 ccgtcagcag gacgacgtga tggctctaca taagctgcat tccatggctc aggtccgata
    45481 gcacgaagga aagtgtaagg actcattgtt cccgcacctt tttcattatc ataagcctgc
    45541 ataagcatac aacattggtc attccaaaat tgttgcaaag taaggatgat ttcctggaaa
    45601 gtcaatttct tagacattgt ttactccttt ttatataaat tacttgcgac atgagtctgc
    45661 ctcgtcgatt atacgaggca agacgagtta gtactgcgtc tagctcaggc actctagtgc
    45721 tgagcgtggg gcagtccgac tgtaaggagg tttctgccac tgatgcagtg aaatgttaat
    45781 ttcttagaca ttgcttactc ctttagtttt tatatttctt tttcaattaa tttctgctga
    45841 acaaaccaat ttaacaaggg aagagtttta tctgtatttg cccatagatg ataagaatct
    45901 aagaccgctt gtacactacc taaattttct accaacttat ctactgtcaa aaagctgcgc
    45961 cagtattcat aaaaaatact tgcatagttc ttatcataag tcgaagaacc aaaatcattc
    46021 aatgaatgcc aaccatactt cttctgaaaa agttctacta gagattgatt acaaattttt
    46081 tccgcttgaa attcctcttc tgtcaagaaa tacttgcgac taatatattc aaccatcccc
    46141 tcttcgaacc agatataaga gtcagaacca tcaaaatcat ctaaaaaatg ctccgaccaa
    46201 tgagctaact catgtcctac aatatgtaag aggaaatttt cagataaaga atgatagtga
    46261 ctttctattg cttgagtttg ctcagaacac tcgtagtcca tcaactgata caaatacaac
    46321 tctttccaaa cagctaaatc aggcgtcata accactcgtc tattatttgt ataggttgga
    46381 acagcacttt ccctaataat ctgtgtagca gcattaaaat ctgaccaaat aacgggttgc
    46441 ggtaaatcac agactgcaag ttcattcttt aaaaaagatt gataatcttt caacttttca
    46501 gtatttctta ctacaaaatc acgaaatgta gctagttgac tatcgtcttt tacaagataa
    46561 aggttgtcca cggctctcct ttctttcaca caatagactg aataagcaaa agaaccacat
    46621 ctgacaatcc taggttgatt taacctaggg gcgtcagaaa cgcggttcca ccctaattta
    46681 ttacttcatt gtttttgaaa atactacaga aagcgccagc tcattatttt gccctacttg
    46741 gctcccactg tcccaagctc gcttgaagaa cgccataaga ctttctttcc tgctgactat
    46801 tatatcaaaa attagaataa tgtacaattc tttttatgat tttctagaaa tccacatcat
    46861 caactcgtgg agcccccgac tgaacagcag tcgtttttaa ggtttctctc tcctcatgac
    46921 tcagttcaat tccaaaacaa tcaagattag cttgaatacg agaggttgtg acagattttg
    46981 gaagtggtaa aaatccttct gccaagctcc aggccaaggc tatctgagca accgattttc
    47041 cgtgatttgc tgctatttct tggacttgct tgctatcaaa cagttctcct tgtccaaaag
    47101 gcccccaagc ttccaataaa attccctttt cacgacagta agctacgact tcctcttgat
    47161 acacacctgg cgccaagcga acttgattga ccgcaggaac gatagttgca gtttcaagca
    47221 aggcatccaa atgatgggga agaaaattgc taacgccgat agcacggatt ttcccttctt
    47281 gatagaggtc ttccatcgct ctccaaactt ccgcattgcg agttttccat gcgtcatttt
    47341 ctctgagcgg ttttgggttc ggccaatgaa tcaaatacaa atccaaataa tccaagccca
    47401 gtttttctat agatttttcc aaagcttgac gagtttgctc ataggtttgc tgactattcc
    47461 aaagcttggt agttacgaac atttcttcac gtggaactcc gctatctttg attgcttgac
    47521 caacactttc ttcattctga taaatcgccg ccgtatcaat atgacgataa ccagccttca
    47581 aggcttctaa cactgcacga taggcttctt ctccatcctt agccttaaaa gttccaaatc
    47641 ccaatactgg aatttctact ccattattta attgataggt attcatatgc ttctccttct
    47701 attttcttta tcatttatag cataattttt ttgctaatta gtactatctt ctgtaaaaaa
    47761 taagtctatc acatatctga cagacctatt ttttcttgct tattcatcac gactatagta
    47821 cagctcatga gcttttaggc gagtattgag catctctggt atggtcacaa aggtataacc
    47881 ttgatttttc aaatactcaa tgacccttgg caaggcattg actgtcggac tgtgaatatc
    47941 atgcatcaaa acgatagatc cgttagctac ttgatgctga atttctgtca aaatagatgc
    48001 ttcattttta ctcttccagt ccagactatc cacatcccac atgataaagc tcaaatccaa
    48061 gctattgcga atatcatctg taatagcacc ataaggtgga cgcatgagtt tagaactaga
    48121 acccagcact ttagttagca catcctcagt atcagtaatc tgctttttag cttcatcaag
    48181 agagagttgc gagagaatcg gatggctcca actatggttt ccaacaacat gaccttcaga
    48241 ttttatcctc ttcaccaagt cctcattccc agaaacattt ttcccaagca caaagaaagt
    48301 cgctttaata ccatatttag ctagggtctc taatacctgc ggggtcgttg ctggatttgg
    48361 accatcatca aaggttagag cgacaacttt ttgatatttc ttatcaaagt aagattggta
    48421 caaggccgca tctttttcga gtaagtacga agattggata acatcaaaga aagcagatac
    48481 tggcaaggct atctcttcta aattttcaac cacaggactt ggataaagga taatctgact
    48541 atccttgtaa tcaaaattcc atgcagacaa gtcttggtca gagaagtttt ttacaatctg
    48601 ctcactctgg tcttgctcta tttttttatc ctctatgaag gaggtcaact cttttatcag
    48661 ctgttcctta gccttactag catctgaaaa cagttggtca agtgtaaaag gttgcccatc
    48721 ttctgttaag tgaacctttc ctagactggt cttttcagtc tcttcaacct taaaagcaac
    48781 taaatcatag atttgtttgg tcacattacg attaacgact ccctttaaac ctgactcttc
    48841 ttgctctgta tagtagaaaa caagattgtc cttactttct agcttgtcct taacatcttg
    48901 atttatcaac tccctaacag aggaaatcac tttctcccct tggagaggat aataggcaat
    48961 cacttcggct tgcccctgac gaaaatgctc cttctgattt ccctcactca attgatcatc
    49021 tttctctttt ttgagcgatt caatcttttg ctcaaaactt ttttgctggt agatcttaaa
    49081 agcaataaat ccgcctaata ggcaaataga aattgctaaa ataccaatca aagccaataa
    49141 tacatgtctc gttttcccgt gtctgccacg tcctagtcta cttttattca tatttatatc
    49201 ataacaaatt tgagcaataa tttcaatgat acaatttggc aatccacaat tcctctagca
    49261 agccaaagca tcttacatca actccaacat ccgtatctgt agagattatg tagttttcta
    49321 tctatggaat ttctagtaga ttgaagctag aatagtagac ctatacttct aaaacattgt
    49381 tagaaatcga tttgattgtc ctgatcgatt tgtcctgttc tcatttcatt ttactataaa
    49441 actatgaaaa gctaggtcat ctgagaagta attactatcg acaattgcga tagcgtatac
    49501 tggtgcgatt tgtttgtagc tctggtgggt atcaccttca cgttggcgaa ttttttctag
    49561 gttttgatta acctgactgc gcagataagc ccataggcga ttgatgaaaa aattctgatg
    49621 atgaacctga atttcgatga taacttagat tccattatct aactccgcca agacgtctat
    49681 actagtatag aaatcctgcg ctgagtaggg catggaaggc aagacgtgaa tgttacttcc
    49741 ctccaaaatc gtcacatttt ttgctggcaa gtccagcata tcgcggataa attgacaaat
    49801 cattagttgg gctgataccc ggatgtctga gaatcctcct tttcctcctt ctattatagc
    49861 acatttttaa atctaggttt gctagattct atgcttctat ctatttattc ggaaaagaaa
    49921 gcttttcttc agaagaaagc tagtagctta tttgaaattt tctcctctct gttggatagt
    49981 cccgtctatc tatgttataa tgaaagaagg atttaaaatc ggaaaaggag tatttatgct
    50041 aaaattaggt gtcatcggaa ctggcgctat cagccatcat ttcatagaag cagcccatac
    50101 cagtggagaa taccaactgg tcgcaatcta ttctagaaaa ctagaaactg cagcaacctt
    50161 tgcttctcgc tatcagaata tccaactatt cgatcaatta gaagtcttct tcaaatcttc
    50221 ttttgattta gtctatatcg ccagtccaaa ctccttacat tttgctcagg caaaagctgc
    50281 cttgtctgct ggtaaacatg ttattctcga aaagccagct gtcactcaac cacaagaatg
    50341 gtttgatttg attcaaacag ctgaaaaaaa taactgtttt atctttgaag cagctcgtaa
    50401 ttaccacgag aaagccttta ctactatcaa aaacttttta gcagataagc aagtgttagg
    50461 agcagatttc aactatgcca aatactcttc caagatgcct gacttgttgg ctggacaaac
    50521 accaaatgtc ttttcagacc gttttgctgg tggagccctc atggatttgg ggatttatcc
    50581 cctctatgct gctgttcgtc tttttgaaaa agctaatgac gcgacttacc atgctcaaca
    50641 gcttgacaat agcattgacc taaatggaga tggtatcctc ttctacccag actatcaagt
    50701 tcacatcaag gctggaaaaa acatcacttc caatcttcct tgcgagattt atacaacaga
    50761 tggaaccttg actctcaaca cgattgagca tattcgctca gctattttta ccgaccacca
    50821 agggaagcaa gtccagcttc ctatccaaca ggctcctcat acgatgactg aggaagtcgc
    50881 tgcattttca cacatgatcc agcaaccaga tctgaatctc taccaaactt ggctggatga
    50941 tgcaggctct gttcatgagc tactatatac catgcgccag actgctggca ttagatttga
    51001 ggcagaaaaa tgaaaaccaa actaccgact gaatggcaag aactgagtga ccaactcggt
    51061 ttccaagaat tcacccccat tcaaactcaa ctatttgagc cccttcttgc tggagaaaac
    51121 ctcctaggag tgagccaaac cggaactggt aagaccctag cgtatctcct accaagtctt
    51181 ctcagactac aaaagaaaaa agcccaacaa ctcttgattc tagcaccaaa tacggaactt
    51241 gctggacaga tttttgatgt atgtaaaacg tgggcagaag ctatcggatt gactgctcaa
    51301 ctcttccttt caggttcaag tcagaaacga caaattgaac gccttaaaaa ggggtcagaa
    51361 attctgattg gaactcctgg ccgtatcttt gaactcatta aacttaaaaa aatcaagatg
    51421 atgaatgtgg aaaccatcat cctggatgaa tttgaccaat tactagatga ttctcagatt
    51481 cactttgtag agaaaatcac tcactacgca cctcgtgacc accaactggt ctacatgagt
    51541 gccacgacca agtttgacca agaaaagatt gtgccgaata cacgcactat tgatctctct
    51601 gatcaaaaat tgaacaatat ccagcatttc tacatgcagg tagaccaacg tcatcgagtg
    51661 gatatgctac gaaaactggc tcatgtagag gatttccgtg gtctagtctt cttcaatagc
    51721 ctgtcagacc ttgggaatgc cgaggaaaaa ctacagtatc gtgatatatt ggctgtttcc
    51781 ctcgctagtg atgttaatgt taaatttaga aaaatcatct tagaaaagtt taaagataac
    51841 caactaaccc tgcttcttgc aactgacctt ttggctcgtg gaattgatat cgatagccta
    51901 gaatgtgtcg taaactttga tattcctaga gatagcgaaa cctacacaca ccgtgctggc
    51961 cgtactggtc gtatgggcaa ggaaggttat gttatcactc tcgtcactca tccagaagaa
    52021 atcaaaaaac ttaaaaagtt tgcaagtatc cgagaaattg tcctaaaaaa ccaagaactc
    52081 tatatcaaat aaagccccat tgctctatac acatccagtg tatggagctt ttttataagc
    52141 aattca
//
LOCUS       DAVDHZ010000011        43967 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000011 DAVDHZ010000000
VERSION     DAVDHZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.011"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            143..2554
                     /locus_tag="VUR46_000805"
     CDS             143..2554
                     /locus_tag="VUR46_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET5456262.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLVKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKISTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            2804..3505
                     /locus_tag="VUR46_000806"
     CDS             2804..3505
                     /locus_tag="VUR46_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456263.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            3507..6215
                     /locus_tag="VUR46_000807"
     CDS             3507..6215
                     /locus_tag="VUR46_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET5456264.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALTTHLQDQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLRLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(6311..6802)
                     /gene="tpx"
                     /locus_tag="VUR46_000808"
     CDS             complement(6311..6802)
                     /gene="tpx"
                     /locus_tag="VUR46_000808"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET5456265.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(6925..7854)
                     /gene="psaA"
                     /locus_tag="VUR46_000809"
     CDS             complement(6925..7854)
                     /gene="psaA"
                     /locus_tag="VUR46_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET5456266.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(7886..8734)
                     /locus_tag="VUR46_000810"
     CDS             complement(7886..8734)
                     /locus_tag="VUR46_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET5456267.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(8731..9453)
                     /locus_tag="VUR46_000811"
     CDS             complement(8731..9453)
                     /locus_tag="VUR46_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET5456268.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            9744..11636
                     /gene="pepO"
                     /locus_tag="VUR46_000812"
     CDS             9744..11636
                     /gene="pepO"
                     /locus_tag="VUR46_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET5456269.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(11759..12388)
                     /locus_tag="VUR46_000813"
     CDS             complement(11759..12388)
                     /locus_tag="VUR46_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET5456270.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            13382..15604
                     /locus_tag="VUR46_000814"
     CDS             13382..15604
                     /locus_tag="VUR46_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET5456271.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            15634..16077
                     /locus_tag="VUR46_000815"
     CDS             15634..16077
                     /locus_tag="VUR46_000815"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET5456272.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(16344..16529)
                     /locus_tag="VUR46_000816"
     CDS             complement(16344..16529)
                     /locus_tag="VUR46_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456273.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(16548..16961)
                     /locus_tag="VUR46_000817"
     CDS             complement(16548..16961)
                     /locus_tag="VUR46_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456274.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(17092..17738)
                     /locus_tag="VUR46_000818"
                     /pseudo
     CDS             complement(17092..17738)
                     /locus_tag="VUR46_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(17915..18565)
                     /locus_tag="VUR46_000819"
     CDS             complement(17915..18565)
                     /locus_tag="VUR46_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET5456275.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            18677..19519
                     /locus_tag="VUR46_000820"
     CDS             18677..19519
                     /locus_tag="VUR46_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET5456276.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            19595..20032
                     /locus_tag="VUR46_000821"
     CDS             19595..20032
                     /locus_tag="VUR46_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET5456277.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            20101..20403
                     /locus_tag="VUR46_000822"
     CDS             20101..20403
                     /locus_tag="VUR46_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456278.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYSGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(20494..21567)
                     /locus_tag="VUR46_000823"
     CDS             complement(20494..21567)
                     /locus_tag="VUR46_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET5456279.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFNWKIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            21723..22400
                     /locus_tag="VUR46_000824"
     CDS             21723..22400
                     /locus_tag="VUR46_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456280.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            22393..23367
                     /locus_tag="VUR46_000825"
     CDS             22393..23367
                     /locus_tag="VUR46_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET5456281.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(23416..25359)
                     /gene="thrS"
                     /locus_tag="VUR46_000826"
     CDS             complement(23416..25359)
                     /gene="thrS"
                     /locus_tag="VUR46_000826"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET5456282.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(25417..25593)
                     /locus_tag="VUR46_000827"
     CDS             complement(25417..25593)
                     /locus_tag="VUR46_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET5456283.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(25600..25740)
                     /locus_tag="VUR46_000828"
     CDS             complement(25600..25740)
                     /locus_tag="VUR46_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET5456284.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(25997..26371)
                     /locus_tag="VUR46_000829"
     CDS             complement(25997..26371)
                     /locus_tag="VUR46_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456285.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPLVILIISLLYSYRFRFSLWWLVGNGLLFYFTIITFGEFILIYLLIYETVALVSM
                     DSGISIKHILQKMKNKKLSQNP"
     gene            26610..27239
                     /locus_tag="VUR46_000830"
     CDS             26610..27239
                     /locus_tag="VUR46_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET5456286.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            27380..27649
                     /gene="rpsO"
                     /locus_tag="VUR46_000831"
     CDS             27380..27649
                     /gene="rpsO"
                     /locus_tag="VUR46_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET5456287.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            28464..29078
                     /locus_tag="VUR46_000832"
     CDS             28464..29078
                     /locus_tag="VUR46_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET5456288.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(29371..30120)
                     /locus_tag="VUR46_000833"
     CDS             complement(29371..30120)
                     /locus_tag="VUR46_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET5456289.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            30253..32589
                     /locus_tag="VUR46_000834"
     CDS             30253..32589
                     /locus_tag="VUR46_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET5456290.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            32691..33368
                     /locus_tag="VUR46_000835"
     CDS             32691..33368
                     /locus_tag="VUR46_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET5456291.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            33355..34152
                     /locus_tag="VUR46_000836"
     CDS             33355..34152
                     /locus_tag="VUR46_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET5456292.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            34169..35272
                     /locus_tag="VUR46_000837"
     CDS             34169..35272
                     /locus_tag="VUR46_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET5456293.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            35528..36547
                     /gene="galE"
                     /locus_tag="VUR46_000838"
     CDS             35528..36547
                     /gene="galE"
                     /locus_tag="VUR46_000838"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET5456294.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            36549..37514
                     /locus_tag="VUR46_000839"
     CDS             36549..37514
                     /locus_tag="VUR46_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5456295.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(37565..37771)
                     /locus_tag="VUR46_000840"
     CDS             complement(37565..37771)
                     /locus_tag="VUR46_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET5456296.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDGPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            37823..38299
                     /locus_tag="VUR46_000841"
     CDS             37823..38299
                     /locus_tag="VUR46_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET5456297.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSHPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            38308..38979
                     /locus_tag="VUR46_000842"
     CDS             38308..38979
                     /locus_tag="VUR46_000842"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET5456298.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            39110..39448
                     /locus_tag="VUR46_000843"
     CDS             39110..39448
                     /locus_tag="VUR46_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET5456299.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            39451..40080
                     /locus_tag="VUR46_000844"
     CDS             39451..40080
                     /locus_tag="VUR46_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET5456300.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            40320..41471
                     /locus_tag="VUR46_000845"
     CDS             40320..41471
                     /locus_tag="VUR46_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5456301.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            41784..42533
                     /gene="truA"
                     /locus_tag="VUR46_000846"
     CDS             41784..42533
                     /gene="truA"
                     /locus_tag="VUR46_000846"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET5456302.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            42523..43296
                     /locus_tag="VUR46_000847"
     CDS             42523..43296
                     /locus_tag="VUR46_000847"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET5456303.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNVGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            43274..43735
                     /locus_tag="VUR46_000848"
     CDS             43274..43735
                     /locus_tag="VUR46_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5456304.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        12675 a         8294 c        10080 g        12918 t
ORIGIN      
        1 atgattcttt ctaatgagtt gttttgtcgc ttttcattat aggtcatatg ggactttttt
       61 tctacacaaa ataggctcca taatatccat agggggttac ccactacaaa tattatagag
      121 ccttttatgt tagtatggaa gtatgataag gaataaaaaa caagattatg tactggccta
      181 caaacaacca gcttcaacca cttacatggg ttgggaagaa gaagctttac cgataggcaa
      241 tggttcttta ggagcaaaag tatttggcct tataggggct gaacggattc aatttaatga
      301 aaaaagtctc tggtctggag gtccacttcc tgatagttca gattatcagg gtggaaatct
      361 tcaggatcag tatgtttttt tagctgagat tcggcaggct ttggagaaga gagattacaa
      421 tctggttaag gaactggctg agcagcacct aattgggcca aaaacgagtc aatatgggac
      481 ctatctgtct tttggggata ttcacattga gttcagccag caaggtacga ctttgtctca
      541 ggtgacggac tatcagagac agctgaatat tagtaaggca cttgcgacga cttcttatgt
      601 ctataaggga acgcgatttg aacgtaaagc ttttgcgagt tttccagatg atctcttggt
      661 tcaatgtttt actaaggaag ggttggaaac tctagatttt actatagaac tatccttgac
      721 ctgtgatttg gcttctgatg gaaagtatga acaggaaaaa tctgattaca aggagtgtaa
      781 gttggatatt actgattctc atatcttgat gaagggaaga gttaaggata atgatctgcg
      841 gtttgctagt tatctagctt gggaaacgga tggagatatt agagtttggt cagatagggt
      901 tcagatatca ggagccagtt atgccaatct cttcttggcc gctaagacgg attttgccca
      961 aaatcctgct agcaattatc gcaagaaact agatttagag caacaggtga tagacttggt
     1021 ggacacagct aaagaaaagg gctataccca attgaaatca aggcatatcg aggactacca
     1081 agccttattc cagcgtgttc aattggattt ggaagctgat gttgacgcat ccactacaga
     1141 tgatttgtta aaaaattata agccacaaga agggcaggct ttggaggagc tgttcttcca
     1201 gtatggacgg tatttattga ttagttcgtc cagagactgc ccagatgctc taccagctaa
     1261 cctacaggga gtctggaatg cggtcgacaa tcctccttgg aattcggact atcacttaaa
     1321 tgtcaatctg cagatgaatt attggccagc ctatgttacc aatctcctag agacggtctt
     1381 tccagtcatc aactatgtag atgatttgcg tgtctatggt cgtctagcgg ctgtaaagta
     1441 tgcaggaatc gtctctcaga aaggtgagga gaatggttgg ttggttcata ctcaagcgac
     1501 tccctttggt tggacggcac ctggttggga ttactattgg ggttggtcac cagctgccaa
     1561 tgcgtggatg atgcaaaccg tttatgaagc ctattcattt tatagggacc aagactatct
     1621 cagagagaaa atttatccca tgttgaggga aacggttcgt ttttggaatg cctttttaca
     1681 taaggatcag caggcgcagc gttgggtgtc ttctccgtct tattccccag aacatgggcc
     1741 gatttcgatt ggcaatactt atgaccaatc tctgatttgg cagttatttc atgattttat
     1801 tcaggctgct caggaattgg gactggatga ggacttgttg actgaggtta aggagaagtc
     1861 tgatttacta aatcctttgc aaatcactca atctggtcga atcagggagt ggtatgagga
     1921 ggaagagcag tattttcaaa atgagaaagt ggaggcccag caccggcacg cttcccatct
     1981 agtgggactc tatcctggca atctctttag ctacaaggga caagagtata ttgaagcggc
     2041 acgtgctagc ctcaatgatc gtggagatgg cggcacaggc tggtccaagg ctaataagat
     2101 caatctctgg gcgcgtttgg gagatggcaa tcgagctcat aaattattgg cagagcagtt
     2161 aaaaatatcc accttgccaa atctttggtg tagccatcct ccttttcaga tagatggtaa
     2221 ttttggtgct actagtggca tggcagaaat gttactccag tctcatgcag cttatctggt
     2281 acctctagct gccctacctg atgcttggtc aacaggttct gtttcaggct taatggcacg
     2341 tggacatttt gaagtgagca tgagctggga agataaaaaa ctcttacagt tgaccatttt
     2401 atcaaggagt ggaggagatt tgcgagtttc ttatccagat attgagaaga gtgtgattaa
     2461 aatgaatcaa gaaaaaataa aagcgaaatg catggggaaa gattgtattt cggtggcaac
     2521 agcagaaggt gatcttgttc aattttattt ttaagaagat gttataaggc agtaatttga
     2581 aacttccttt taataaggat ttaagaatat aggcagtttc caactagttg aaaaagcgtt
     2641 ataatgataa taggaagtaa tactcaatga aaatcaaaga gcacaaacta ggaagctagc
     2701 cgcaggttgc tcaaaacagt gttttgaggt tgtagatgga agctgacgtg gtttgaagag
     2761 agattttcga ggagtataat ttgtttgata gagggtggat ctgatggctt atattgagat
     2821 gaaacactgt tacaagcgtt atcaggttgg ggacacggag attgtggcca atcgtgatgt
     2881 gaattttgag attgaaaagg gggagctggt tattatcctt ggtgcttcag gtgcaggcaa
     2941 gtcaacagtt cttaaccttc ttgggggaat ggataccaat gatgaagggg aaatctggat
     3001 tgatggtgtt aatattgcgg attatagttc ccaccagcgc accaattacc gtagaaatga
     3061 tgtggggttt gtttttcagt tttataatct agtttctaat ctgacagcta aggaaaatgt
     3121 ggaactggct tctgaaattg tgacagatgc cttgaatcct gatcaggtct tgacagatgt
     3181 aggtctggct catcgtctca ataactttcc agcccagctt tctggagggg agcaacagcg
     3241 agtctccatt gcacgcgcgg tagccaaaaa tcctaaaatt ctcctttgtg atgaaccgac
     3301 tggagccttg gattatcaga cgggcaagca ggttttgaaa attctccaag acatgtctcg
     3361 tcaaaaggga gcgacggtga tcatcgtgac tcataatgga gctttggcgc ccattgctga
     3421 tcgcgtgatt caaatgcacg atgccagtgt caaggatgtg gtgctcaacc agcatcctca
     3481 ggatattgac agtttggagt actagcatga tcaagcgaaa aacttattgg aaggacttaa
     3541 ttcagtcctt cacaggctcc aaggggcgtt ttttatccat cttgatcctg atgatgttgg
     3601 gatctctagc cttagtaggc ctcaaagtaa ccagtcccaa catggaggcg acagctaatg
     3661 cttatttaac aactgctcaa accttagatt tggcagtcat gtctaactat ggcttggatc
     3721 aagcagacca agaagaacta aaacagacgg agggcgcaga ggtcgagttt ggctatttga
     3781 cagatgtgac tatggataat gggcaggatg ccattcggct gtactccaaa ccagagcgaa
     3841 tttcaacctt tcagctaaga aagggacgac ttcctcagtc agacaaggaa atcgctttga
     3901 ccactcattt gcaagaccaa tacagcgtgg gacaggagat tagttttaaa gaaaaagaag
     3961 agggtcattc ctctttaaaa gaccatactt ataccattac tggttttgtg gattcggctg
     4021 aaatcctctc ccagcgagat atgggctacg caggaagtgg aagtgggact ctgacagcct
     4081 atggggtgat tttacctagt caatttgatc agaaagtcta caatatagct cgtttgaaat
     4141 atcaagattt agcaggttta aatgcctttt catcagctta tgaagaaaaa tccaagcaac
     4201 atcaggaaga gcttgaacaa attttatcag ataatggcaa ggtacgtctg cgacttttga
     4261 aaaaagaagg acaagagtct ctagacaagg ggcaagagac ccttgacaag gctcagacta
     4321 atttgcagga aggcaagcgt cgtttagcag ctgctcaagc tcgtatacag gctcaagaaa
     4381 gtcaactagc cttgtttcct caagctcaga gagaacaggc tagtgctcaa cttacccaag
     4441 ccaagcagga attgggcaag gaagaggaca aactaaagca agctgaacaa aatctagccc
     4501 aagaaaagga aaaattagaa aaacatcagc aagtcttgga tgatttggcg gagccaaggt
     4561 atcaggttta taatcgtcag accatgccag gtggtcaggg ctatcttatg tatagcaatg
     4621 cttcatccag tattcgagca gtgggcaata tctttcctgt ggtactttat gccgtagcag
     4681 ccatggtgac ctttacgacc atgactcgct ttgtagacga agagcgaact catgcaggga
     4741 tttttaaggc cttgggttac cgtagtaagg atattatcgc caagtttctc ctttatggac
     4801 tagtagctgg gactgtcgga acggctctag gtagtatact tggtcattat ttgctagcca
     4861 gtgtaatttc aagtgtcatt acaaaaggca tggtggtggg agaaacccag attcagttct
     4921 attggaccta tagcttacta gctcttgtct tgagctggtt ggcgagtgtg ttaccagcct
     4981 atctggtggc ttggagggaa cttcatgccg aagcagccca gcttctactt cctaaacctc
     5041 ctgtcaaagg agctaaaatc ttattggagc gtatcggttt tatctggcgt cgtctcagtt
     5101 ttactcataa ggtaacagcc cgcaacatct ttcgttataa gcagagaatg ttgatgacaa
     5161 tctttggtgt ggcaggttct gtagctctgc tctttgcagg tttgggaatc caatcttctg
     5221 tagcaggagt tccgtctaaa cagtttcaac aaatccaaca gtatcagatg cttgtctctg
     5281 aaaatcctag tgcgaccaat caggacaagg tagagctagc agaagtgttg aaagggcagg
     5341 agatactagc ctaccagaaa atctattcta aaacgctaga caaggatttc aaaggcaagg
     5401 ctggtcttca aaacattact cttatgatga tagagaagga agatttgact ccctttatcc
     5461 atcttcaaca tcatcagcag gagctgacat taaaagatgg catcgttatt acagctaaac
     5521 tcgcccagct ggcaggtgtc aaggttgggc agactttaga aattgaaggt aaggaactaa
     5581 aggtcgctgc tattactgag aactacgttg gtcactttat ttatatgagt caggctagct
     5641 atgagcaact ttacggacag ctaccccaag ccaacactta tctggtctca ttaagggata
     5701 ccagtgcaac tagtatcgaa agtcaggcgg gcttgcttat gaatcaatct gcggtgtcca
     5761 gcgttgtcca aaatgcttca gccattcgac tcttcgactc tatcgctagc tcactcaatc
     5821 agaccatgac catcttggtc atcgtatcgg ttctattagc tattgtcatc ctttacaatc
     5881 tgaccaatat caacgtagct gagagaatcc gtgaactctc cactatcaag gttctcggtt
     5941 ttcataataa tgaagtcacc ctctacattt accgtgagac gattgtgctg tcccttgtgg
     6001 gaatcgtact tggtctggta gctggtttct atttacacca atttttgatt caaatgattt
     6061 cgcctgcgac tattctcttt tatccgcagg taggctggga agtctatgta atcccagtgg
     6121 caacagtaag catcattttg accttgcttg gtttcttcgt caattattat ctgagaaagg
     6181 ttgatatgtt agaagccctg aaatctgtag agtaaggtag ttatttttag ctgattgaac
     6241 ttctatttac taatattcaa aaatcctctg tcacaaagag cagggagctc tttgtgacag
     6301 aggatttttt ctatagggct ttagcagctg caattgcggc ttcgaagttt ggctcagaat
     6361 tgatattatc cacgtattca acgtagcgaa tcgtattgtc agtatcgagg acaaagactg
     6421 cgcgtgctaa taggtgccat tcgttgatca agagggcata atcgcgcccg aaagaatggt
     6481 caaagtagtc tgaaagcata atggcattgt caaggccttc agcaccgcac caacgttttt
     6541 gagcaaaagg taggtccatt gaaacagtca atacgaccgt gttgtccagt ccagccaatt
     6601 cttcattaaa acgacgtgtt tgagttgagc agatacctgt atcgatagaa ggaacgacac
     6661 tcaagacttt tttcttgcca tcaaaatcag ccagagattt tttagaaaga tctgttgtag
     6721 taagagaaaa atcaagcgcc ttgtcgccga cttgtagttg tttacctgta aagctcacag
     6781 gatttccgag aaaagttacc ataggatact ccaatctttt ttcttccatt gtatctaaaa
     6841 cagtcagaat tttccaatga tttgaccgga aatgtgtgca tagaaaaaac gccagctcac
     6901 atgagaatga cgtttttcag aggcttattt tgccaatcct tcagcaatct tgtcaaggtt
     6961 gtatttcatc atgctgtagt agctgtcgcc ttctttacct tgttctgcga tagagtcagt
     7021 aaagatttgt gcgtagattg ggatgtttgt gtcttgagaa acagttttca ttggacggtc
     7081 atccacactt gattctacaa agagtgatgg aacttttgtt tggcgaagtt tttcaaccaa
     7141 ggtcttgatt tgttcaggag ttccttcttc ttcagtattg atttcccaga tgtaggcact
     7201 tgggacacca taggctttag agaagtattt gaatgctcct tcgctggtta caatgagttt
     7261 cttttcagca gggatcttat taaatttatc cttactttct ttatcaagtt tgtctaactt
     7321 atcagtatat tctttgagat ttttttcata gaattcttta ttgttagggt ctttggcgct
     7381 caattgtttg gcgatatttt tagcaaaaat aataccgttt tcaaggttaa gccaagcgtg
     7441 tgggtcttct tttccttttt cattttgacc ttcaaggtag ataacatcaa cgccgtcgct
     7501 gactgcgaag tagtctttgt tttcagtttt cttggcattt tctaccaatt ttgtaaacca
     7561 agcattgcca cctgtttcaa ggttgatacc gttatagaaa atcaaatcag cctcagaagt
     7621 tttcttaacg tcttcaggaa gtggttcgta ttcgtgtggg tcttgcccaa tcggaacgat
     7681 actatgaagg tcaattttgt caccagcaat atttttagta atatcagcga tgattgagtt
     7741 tgtagcaaca acttttagtt tttgaccaga agttgtatct ttttttccgc tagcacatgc
     7801 tacaagaatg attgcagaaa gaaagagaac gagtaatgta cctaattttt tcattagatc
     7861 ctccaattta ttagggcttt gccccttatt ttaacaaatg tttatttttc agtttcaaat
     7921 atcgttgttt gggagcgata aagaagctaa tgagaaagaa actagcagct gtaagcacga
     7981 tactagaacc tgccgcaaca ttaaaactat agccaataaa gagtcccaaa actgaagcag
     8041 tagctccgaa ggttgaggaa aggaaaatca tacttttcag actattagca tacagataag
     8101 cagttgcagc tggggtaatc agcatggcta caatcaggat agttccgaca ctttgcatgg
     8161 ctgtcacaga cacgagagtc aggagtacca tgagaaggta gtgatagaaa ttgacaggca
     8221 ttcccatggc tttagccaag agttcatcaa aggaagttat caagagttgc ttgaagaaaa
     8281 tccagattaa caagaggatg gctgccccca cacccatagt aataaacata tccgtatctt
     8341 ggacggccag gatattacca aaaaggatat ggaaaaggtc agttgaactt ttagcgacac
     8401 caatcaagat gataccgagg gctaagaaag aagaaaaggt aatgccgatg gcggtatcgc
     8461 ttttgataat cgagtttcct ttgatgtagg taatgatgat ggcagctagc aatccaaaga
     8521 caatggctcc gataaagaag tcaaggccca agatgaagga gagggctaca cctggtaaga
     8581 cagcatgtga aatggcatct cccatgagtg acatcccgcg tagaataatg aaacatccca
     8641 cggctccagc tacaatcccg acgacaatag ctgttatcaa ggcattttgt aggaaatgga
     8701 atttttgcaa tccatcgata aattctgcaa tcataggtca cctccattga aaaagagttg
     8761 attaccgtaa gcttctttta gattggtttc ggtaaaagtt tcttttgttg gaccaaaggc
     8821 aatcacttct cgattgacaa gtaagacttg atcgaagtag tggggaatct tgctgaggtc
     8881 gtggtgaacg atgagaaccg tcttcccagc ttttttcaaa tctctcagcg tattcatgat
     8941 gatttcctca ctgacagagt caatcccagc aaagggttca tccaagagga tatagtcggc
     9001 ttcctgcacc aaacatctgg caatcaagac ccgctggaat tgacctccag acagttgact
     9061 aatttgacgt tcagcgtagt cagctaggcc gacgatttca agggcctctt gcactttctt
     9121 ccaatgttta gcctttaaac ttcgaaagag aggaatagag ggaaatagtc ctaacgagac
     9181 gcattccttg accttgatgg gaaagttgta gtcgatattg attttttgtt cgacataggc
     9241 aattcggtgt aaggattttt taacttcctt gtcatcgaga aatgcctgac cttgatgtgg
     9301 gataattccc agcatacctt ttaatagtgt tgatttccca gcgccgtttg gaccaatgat
     9361 gccggtaatt gttggtccat ggagcactag tgaaatatcc ttaagtgcca acgtttcttt
     9421 gtaggagaca ctgaggtttt cgatacgtat cataaacttg tattcctcct gtctcttaat
     9481 atacattaaa aaaaaaatta agtcaagtta atttttgaaa aaattaaaat aataactgaa
     9541 aaatagattc taaagataac tttcaggata aatttctaaa ttataaaacg catagtatca
     9601 agtgtaaaaa acttggaatt atgcgtttta tcatggaaag attttttata atagctaaaa
     9661 aataatagtt aaatggttat taattgcatt ccctagtgat ttttgttaag ataaatgcaa
     9721 atacaaatga aagcgagaac aagatgacac gttatcaaga tgatttttat gatgctatca
     9781 atggagaatg gcaacagaca gctgaaatcc cagcagataa gtctcaaaca ggaggttttg
     9841 ttgatttaga ccaggaaatt gaagacctga tgctggcgac aacagacaag tggttagcag
     9901 gtgaagaagt gcctgaggat gctatcttgg aaaactttgt caaataccac cgcctagttc
     9961 gtgattttga caagagagaa gctgacggta tcacacctgt cttaccactc cttaaagaat
    10021 tccaagaatt ggagactttt gcggatttta cagctaaact agcagagttt gagcttgcag
    10081 gaaaaccaaa cttccttcct tttggtgtat cgccagactt tatggatgct agaatcaatg
    10141 ttctatgggc tagcgctcca agcacaatct tgccagatac gacctactat gcagaagaac
    10201 atcctcagcg cgaagagctc ttgactcttt ggaaagaaag cagcgcaaat ctcctcaagg
    10261 cttatgattt ctctgatgaa gaaattgaag acttgctaga aaaaagactt gaattggacc
    10321 gccgagttgc ggcagtggtg ctctctaatg aagaaagttc agaatatgct aaactctatc
    10381 atccatattc ttacgaagat ttcaagaaat tcgcgcctgc cctacctttg gatgacttct
    10441 tcaaagcagt tattgggcaa ttaccagaca aggttattgt agacgaggaa cgtttctggc
    10501 aagcagcaga gcaattctac agtgaggaag cctggtctct ccttaaagca accttgattt
    10561 tgagtgttgt caatctttca accagctatt taacagagga tatccgtgtt ttgtctggtg
    10621 cctacagccg tgccctttct ggagttccag aggcaaaaga taaggtcaaa gcagcttatc
    10681 atctagcaca agaacctttc aagcaagccc tgggtctttg gtacgcccgt gagaagttct
    10741 ctccagaagc caaggcggat gtggagaaaa aagtggcaac catgattgat gtttataagg
    10801 agcgtctgct taagaatgac tggctcactc cagaaacctg taaacaggct atcgtgaagc
    10861 tcaatgtgat caaaccttat attggctatc cagaagaatt gcctgcacgt tacaaggata
    10921 aggtagtgaa tgaaactgcc agtctttttg agaatgctct agcctttgcg cgtgtggaaa
    10981 tcaagcacag ttggagtaag tggaaccagc ctgtagacta taaggaatgg ggcatgcctg
    11041 ctcatatggt caatgcctac tacaatcctc agaagaacct gattgtcttt ccagcagcca
    11101 ttttacaggc gcctttctat gacttgcatc agtcatcttc tgctaactac ggtggtattg
    11161 gggcagtgat tgcccatgaa atttcccacg cctttgatac taacggggct tcctttgacg
    11221 aaaatggtag cctcaaggat tggtggacag agagcgacta tgctgccttc aaggagaaaa
    11281 cacaaaaagt cattgaccaa tttgatggac aggattctta tggagcaacc attaacggta
    11341 aattgactgt atcagaaaac gtggctgact tgggaggaat cgcagcagcg cttgaagcag
    11401 ctaagagaga agcagacttc tcagcagaag agttcttcta caacttcggt cgcatctggc
    11461 gcatgaaagg tcgaccagaa tttatgaaac ttttggctag cgtcgatgtg cacgcaccag
    11521 ccaaactccg tgtcaatgtg caagtaccaa acttcgacga tttctttaca acctatgatg
    11581 tcaaagaagg agacggaatg tggcgttcac cagaggagcg cgtgattatt tggtaataca
    11641 aaaaatctag tcatcagaaa aaaggcatcc aatcacgtgt gaaaaccttg ataggatgcc
    11701 ttttgtaata gaaagatttg ctggatagtt tacttaaatt tcgattgtca tcatcttgct
    11761 agaaaaaggg attgaaggcc ttttcgtgag cgatagtagt agctggacca tgtcctggat
    11821 agacatcgta gtttggtagg gtgaagagtt gggtctggat actatgaagg agttgctcca
    11881 tgctaccagt cggaaggtcg gtccgtccga tagtttcgcg gaatagagca tctcccgtca
    11941 agactaggtg agcatcagga aagactaggg aaacaccacc gatagagtgc cctggggtcg
    12001 gtagaacctt aaaacgaaat tcctctagtt ggtattcttc gtgaaagaca aaggtgtgtt
    12061 ctgcaggttt tgtgaccaca tctgccatat catcgtggcg agggagaccg gagagattat
    12121 cgacaggagt gtagagccag ctggcttcgc tctctgcgat atagacagga ggattgccaa
    12181 acgtctcgcg aaccaagtcc agactcatga tatggtcata atgggcgtgg gtcaagagaa
    12241 tagcacagat cggtttgttg atcttctcga ttgtctgacg aatggcttcc caatgactac
    12301 caggatcgac gacgatgagg tgcttttcgc cttctagata ataggtattt tcataggcaa
    12361 caggattcac ggttttatgg attttcatac tagctccaat ctcaaagaat gtactaatac
    12421 tcttcgaaaa tctcttcaaa ccgcgtcaac tttatctgca acctcaaagc agtgctttga
    12481 acagcctgcg gctagctttc tagtttgctc tttgattttc attgagtata aattaagtat
    12541 agcacagtta gggagaatag gtaaggattt aaaatgaact taaaaaccag catgactaga
    12601 tgaagacagg ctggttatca atttatcaat attggaaagg tgtcaattgc ccttcatagg
    12661 ttgcataaac tccgtcatta gcttgtttga tagacgtgat gtttagagtg ctaccgtagt
    12721 tggcttctca tttgtcgcta tattcactat aagttatcct actgggcagg ttctggtcgt
    12781 tagcatagta ttgaacgagt tttttatagc tttgctggct gaataggaac aggcagcaaa
    12841 ctcctaacat taggagagca aagatagaaa tagcagtttt tttcataggt attctcctta
    12901 taaactaaag gatagaagaa agtatcttga ggatttttat actcttcaaa aatctcttca
    12961 aaccgcgtca acgtcgcctt gccgtatata tgtgactgac tttgtcagtc ttatctacaa
    13021 cctcaaagca gtgctttgag caacctgcgg ctagtttcct agtttgctct ttgattttca
    13081 ttgagtatta attccaaaat ccagtcaagg taccagtgta tgtgatacga gttccaccgt
    13141 ttatctttcg tatcttcaat ggaattgggg aaatcagaaa gtctttgggt tacaatatgg
    13201 tttccgttct tctatctctc cttctatcac ctaagtttaa aatctaactt cgtagtatat
    13261 tatgggtcaa taattcagaa ttatcaagca attttgaatt atttttttct tattctgttc
    13321 caatctagtt ttcatattct taaaaaagtg ataaaatggt aggaagaatt ggagagtaga
    13381 gatgccgaaa gaagtgaatt taacaggcga agaagttgtc gctttaacca aagaatattt
    13441 aacggaagag gatgttcatt ttgtccataa ggccttggtc tatgctgttg aatgccacag
    13501 tggtcaatat cgcaaatcag gcgagcctta tatcattcac cctatccaag tggcaggtat
    13561 tttagctaag ctaaagctgg atgctgtaac agtagcttgt ggattcttgc atgatgtggt
    13621 ggaagataca gatgcgacct tggacgattt ggaaagagag tttggtcctg atgtgcgggt
    13681 gattgttgac ggagttacca agcttggcaa ggtcgagtac aaatcgatcg aggagcaatt
    13741 agcggaaaat catcgcaaga tgctcatggc catgtctgag gatatccgcg ttattttggt
    13801 caaactgtct gaccgcttgc acaatatgcg gaccctgaaa catcttcgaa aagacaagca
    13861 ggagcgtatt tccaaagaaa ccatggaaat ctatgcccca cttgcccatc gtttggggat
    13921 ttccagtgtc aaatgggaat tagaagactt gtctttccgt tatctcaatc caacggagtt
    13981 ttacaagatt acccatatga tgaaggaaaa gcgcagggag cgtgaggcct tggtggatga
    14041 ggtagtcaca aaattagagg agtatacgac agaacgtcac ttgaaaggga agatttatgg
    14101 tcgtcccaag catatttact caattttccg caaaatgcag gacaagagaa aacggtttga
    14161 ggaaatctat gatctgattg ctattcgttg tattttagat acccaaagtg atgtttatgc
    14221 catgcttggt tacgtgcatg aattttggaa accgatgcca ggtcgcttca aagactatat
    14281 tgccaaccgc aaggccaatg gttatcagtc tatccatacg actgtttatg gaccaaaagg
    14341 gccgattgaa ttccagattc gaaccaagga aatgcacgag gtggctgagt atggggttgc
    14401 ggctcactgg gcttataaga aaggtataaa ggggcaagtt aacagcaagg aatcagctat
    14461 tggaatgaac tggatcaagg agatgatgga gctccaagac caggctgatg atgctaagga
    14521 atttgtggac tctgttaagg aaaactatct ggctgaggag atttacgttt ttaccccaga
    14581 tggagctgtc cgttcccttc ccaaagattc aggaccgatt gattttgcct acgaaatcca
    14641 taccaaggtc ggtgaaaaag caactggtgc caaggtcaat ggccgcatgg ttccactgac
    14701 aaccaagtta aagacagggg atcaggttga aattatcgcc aacccgaact cctttggacc
    14761 tagccgtgac tggctcaata tggtcaagac tagcaaggcg cgcaataaga ttcgccagtt
    14821 ctttaaaaac caagataagg aattgtctgt caacaagggt cgtgagatgc tgatggctca
    14881 gttccaagaa aatggctatg tggcaaataa atttatggac aagcgccaca tggatcaagt
    14941 tctgcaaaag accagttaca agacagaaga ctccctcttt gcggccattg gttttgggga
    15001 aatcggtgcg attaccgtct ttaaccgtct gactgaaaag gaacgccgtg aggaagagcg
    15061 tgccaaggcc aaagctgagg cagaggagct tgtcaaaggt ggcgaggtca aggttgaaaa
    15121 taaagaaacc ctcaaggtca agcatgaggg gggagtggtt attgaaggtg cttctggtct
    15181 cctagtgcgg attgctaagt gttgtaaccc cgtgcctggt gacgatattg ttggctacat
    15241 taccaagggt cgtggtgtgg ctattcaccg tgtggactgt atgaacctgc gtgcccaaga
    15301 aaactacgag caacgtctcc ttgatgtgga atgggaagac cagtactcta gctcaaataa
    15361 ggagtatatg gcccatatcg atatctacgg tctcaaccgt acaggactgt tgaacgatgt
    15421 actgcaagtt ctttcaaata caaccaagaa tatttcaacg gtcaatgccc aaccaaccaa
    15481 ggatatgaag tttgctaata tccatgtgtc cttcggtatt gccaacctct ctacactgac
    15541 cacggttgtc gataaaatta agagtgtgcc agaagtttac tctgtcaaac ggaccaacgg
    15601 ctagttgtcc tagctcttac tagaaaggct attatgaaaa tcattatcca acgggttaaa
    15661 aaagcccaag tgagtataga aggccagatt cagggaaaaa tcaatcaggg acttttattg
    15721 ctggttggtg ttggaccaga ggaccaagag gaagatttgg actatgctgt gagaaaactg
    15781 gtcaatatgc ggattttttc agacgcagaa ggcaagatga acctgtctgt caaagatatt
    15841 gaaggagaaa tcctctctat ttctcagttt accctctttg cggatactaa gaaaggcaat
    15901 cgtccagcct ttacaggggc agctaaacct gatatggcat cagacttcta tgatgctttc
    15961 aatcaaaaat tagcgcaaga agtgcccgtt cagacaggca tctttggagc agatatgcag
    16021 gttgagctgg ttaataacgg acctgttacc attatcctag atactaaaaa gagatgagaa
    16081 agaccaagcc cagtcggctt ggtctttctc atctatcata aaatactcca aaaagaaatc
    16141 ggttcttgat atgcttgggg gaagtctctt ttcaggcttt ggcagatgcg ataggaaggg
    16201 atgagatgtc ctaggatgag gagagttccc tgaaggaaaa gtggaatatc acttaaagac
    16261 accaaggaga gaatcatcag gctatcccat aggagaattt gtaaagcaaa acgccagaat
    16321 ctcggtctaa tctgggaata gagttaacta aagtggtcac aaagttggtt tgaaagatag
    16381 gtcaatagca caggatgaaa gaaaatgagc caaccgctat aaatcaaaat ccagtcccaa
    16441 gtaagctccc ttttaaatgt caaaaatgcc agcatgattc catcaatgac aaggagttga
    16501 atggttttga tgaagatgat ttttttcatg ctaaaacctc cttttcctta gagacactcc
    16561 cataaagaga tgtgtttgtc gtaaaagtct ggatagtttt ctcctaggta gtcagctgtc
    16621 atataataaa aagtagaatg gcgagcagtg atgattggca taagagatga aaaacgctga
    16681 gaactaatga aggctaagag aacaaaaaat agaaaatcaa tggtgagaat ccctaaatag
    16741 tagaagcgaa tctttttatt gatttgagga taaatctcag cgaattgatg tttgagtcgg
    16801 acgaccaaga gaaatagcag gagtccttga gcaaggaaga aaattaaacc agagagcaag
    16861 agccactcaa aagatgtctc gagtctagtg ataaaaaatg caaatagtag caaatcaata
    16921 actgcaattg ctataaaatg gattctatag agttttttca tgacaagacc tccctctttt
    16981 atctaacttc attctactct aaaagaatgg gagttacaac taaaatgata aaaatagcag
    17041 aggggagatt ctcttaagtt gactagtatt ctttatttga gtttccttct attatctaac
    17101 ttcttcatca ttccagacaa ataaagctcc gattgcattg aggatataaa agatgtattt
    17161 accgatattg gcgaagtttc cttgaatacc agcttttgtc agctgaacga aattgtaaat
    17221 caaccaaaag ccccactgtc cctcattgca aatgcattca aagcattggc aatgagggac
    17281 agtgcaaagg caatagttgt tacgtaggca aggagattca tcttgccccc atatccgata
    17341 tagttggtca caaaggcaaa gaggaaggcg atgatggaaa tgatgatggc cgccaatttt
    17401 acctgttttt ggctcatttg gttgggtctg ccttcttgcg aagctttcca tttctttata
    17461 gcaaaggtat aaatgaggaa ggtgacggga taggtaatga tggccgcctt atttccaagg
    17521 atataatcaa tagcaccgga caaaatggta ttaacaatac caaagtaatt tccccatttg
    17581 cttaatttcc ccgtgaaacg agtggacaac atggaaatcc caacgttggt tacggaaatc
    17641 aatccaaagg gtacaagagc tgtccatagt ccccagtcta caaatttatc gaggcgtgag
    17701 ttgagataac cagatgcaat cgcaatccca acgaccaaag caaccccgaa gaggtcaaat
    17761 catttagatg tagcaaaaat ttttagtgat tttttcatag gttaaactac ctttcttttt
    17821 ttcaaatact ctaccaccaa atgaaagtaa aatcaaatga tagaaataaa accctgaaaa
    17881 taaaactttc agggttggta gggaacttga gaaattagtt gattttctcg acatagagtt
    17941 gttttgcaat gtccatattc acttgtaaat cctcgtcgtt actgaggata gtgaaggtat
    18001 tgctgaagcc atcaaactgc ttgacttgga gctggtcacc gatgtgaagt gagtgcttgt
    18061 ccagataatg gagaatgtca aaactatcgt gcacccgagt caggcggtag gcgccagctt
    18121 ccttgatatc agctagtggg aggttattga tttcaacgag gagttctccc ttggcaggaa
    18181 tagttcctcc gtgggggcag gttttaggga aacctagcag tttatctagt ctttccacga
    18241 acaggtcaga gacagtgtgt tccaagacct cagcttcctc gtgaatctgg tcacttgtat
    18301 agtctaaatg atgaactaga aaaacttcaa tcaagcggtg cttacgatag agctcagaga
    18361 ccagtttgag accgaggtca gtcagtagat agccacattc cttgtccttt aggatgagat
    18421 tttcactttt cattcgtttg atcatttcag ttacggcagg gggagagact tgcatgcgag
    18481 ccgcaatttc cttgttggta atcttatgca ggtctatgcc aatttcataa atacatttta
    18541 gataatcttc tttgtttggg gtcattcgtt tcctcttgtc taatatcttt atctagtata
    18601 tcaaaaaaag ctagatttct ctagctgtga ctttttatgt tatacttatt gcaagagaaa
    18661 aaacgaggag atggatatga cgaaaatagc tcttctttca gatattcatg gaaataccac
    18721 cgccttggag gctgttttgg cagatgctca gcagctagga gtggatgaat actggctttt
    18781 gggagatatt ctcatgccag ggacaggacg tagaaggatt ttggacttgt tggatcaact
    18841 accgattacg gctagagttt tgggaaactg ggaagacagt ctttggcatg gtgtccgtaa
    18901 ggaattggac agtactcgcc ccagtcaacg ctatctcttg cgccagtgcc agtatgtttt
    18961 agaggaaatt tccctagaag aaattgaagt gctccacaat caacctcttc aaattcatcg
    19021 tcagtttggg gatttgacgg tgggaattag ccatcatctg cctgataaga actgggggcg
    19081 agagttgatt catactggca aacaagagga gtttgaccgc ttggtgactc atcctccctg
    19141 tgatattgct gtttatggac atattcacca gcagttgctt cgttacggga ctggtgggca
    19201 attgattgtc aatccgggtt cgattggcca acctttcttt ttggacgctc agctacggaa
    19261 ggacttgcgg gcccagtata tgattttgga gtttgatgac aaaggcctgg tagatatgga
    19321 cttccgacgg gtagactacg atgtggcagc ggaattgcag ctggctaaag acctgagact
    19381 tccctatttt gaggtttact atgaaagtct ggtcaatggg atccaccata ctcatcatca
    19441 ggaatttttg agagaattgg ctcagaaaga gggctgcgat cgggagttag acgactggtt
    19501 gaaaagtggt aacgattgac attacaacta aaaagggtat aataatagaa aaagaagagt
    19561 agaggcaggg tagcctcgta aaaaggagaa gaggatgcaa attccaagta gatttaccat
    19621 tgcaactcat atgctgataa tcattgccct cgaggggaag gaaagcaagg tgaccagtga
    19681 ttttctggct gctagtgttg gggtcaatcc tgtcattatc agaaagatct tgtcccagtt
    19741 gaagaaggca gagctgattt cagtagcgcg tggaacgggc ggaacagaga ttgtcaagga
    19801 ccttaaggat attagtcttt tagatgttta tcaggcggtc gaatgtcttg gtaagacagg
    19861 tcaactcttc agtttccatg acaatccgaa tccaaattgc cctgtaggag ctcatattca
    19921 tgatgttttg gatcaaaaat tggagagaat tcagttgact atggaggcag aacttggtca
    19981 gaccagtcta gaaaaagtcg tggccgatgc agagagtcag atgaaggatt aagagggata
    20041 aatgccctct ttttttcttt ggataattat gataaaatgt agctattaaa ggagtaagaa
    20101 atgtatctcg ttatagaaat tgtattagcc tttatagtgt cattttggaa ggataataga
    20161 agtttgtgga atccagtatt atttttatta tccctcattt caagttattt ttatctatcc
    20221 tacctttttt ataaaaatgg atacgagaat gttcagttag ctttttatgt atttgccttt
    20281 gtcttacttc cttttttgct ttttctaagt ggcatctttt taatctatag tggggtcatt
    20341 ttgttgaaac gagagggacg ttccaagccc cattatctct caatgctctt tgatttttat
    20401 tgactattag attctattta aaaagactta gaatgcacat gaaagtatgt attctaggtc
    20461 ttttgttttg tatacattta attttcaaga gtattatcta tttttccatg catggtaacg
    20521 agtatcaatc aataactggg taaggcgacc caaggtttct ctttcttctg gagtgaggga
    20581 ttgagcttgg acaaagagat gatgaatgta ttcaagcgcc tttaaggaag ccaagtcatt
    20641 gatagagcta ataccagcat caagaatagt gccaaagaag aggtcgaagt agagctgaag
    20701 ttcttcgtca gggactgtgg ccacccattc tttaaaggtt gtgtctactt gccggctatc
    20761 actgttggtc ttatccagtt gaacgaagtg cttgtcctca atcttccaat taaaggtatc
    20821 gtgctgggcg atgccaccca gggcagtact ctgaacgatg atttggtgag caggaatttc
    20881 cagcatcata ccgataatgg aaccttgtgg aatgaatatc ttgcttctat ccattatcct
    20941 ttgataaccc gcagtctgtg tcaattcttg atggagacca ggtgcatcaa atgtataaac
    21001 tgctgtgatc tgattttgca aactttgctc aatttggcta gcagcataga tagcgagatt
    21061 tcctcccttg gaatgcccag ccagaataac cttttgctta ggatgatggg caaaaaagtt
    21121 ctttaaatag cgaagggcgt gcttttgagc aggaatttcc ttcatatagg tcaggtggaa
    21181 atcttccttc cagccaatga tactgtcatc tgtcccacga aagacaatca gataggtatc
    21241 gaggctgaca cgataagtca tagccgcaaa ttgcttttgc agttcagggt cgatgtcgtt
    21301 gataaaatgg gagagtttgc aatttttgaa gcgcttgtgt tgagccaatt catctaataa
    21361 ttgaaggcga tttttgctag taagcatggt gggctctctt ggaacctgag gtgctagatc
    21421 taaaagacgt tgaggaagtg tggagaccag attatcaaag gagaggtagg tgatttctat
    21481 taaggttaga atgtctaact cattcaaggg aaggtcgtaa taagaatcat atgcgacatc
    21541 tttcagatag tcaaaaatat tggccataag agctcctttc tttttattta tcttagcaaa
    21601 tttccctcaa attagctagt agcattgcct gtttgtactg gctaaaaaca ggctatttca
    21661 aattcagttt cagaccatct ggcatggaaa aatctgttat aataatggaa aaggagaagc
    21721 gcatgcacaa gattttatta atagaagatg atcaggtcat tcgtcaacag attgggaaaa
    21781 tgctctctga atggggattt gaagtggtcc tggtagaaga ctttatggaa gttttgagtc
    21841 tatttgttca gtcggaacct catctggtcc tcatggatat tggtttgccc ttgtttaatg
    21901 gttatcactg gtgtcaggaa atccgcaaga tttccaaggt acctatcatg tttctttctt
    21961 cgagagacca ggctatggat attgtcatgg caatcaatat gggggcggat gactttgtga
    22021 ccaagccttt tgaccagcag gttcttttag ctaaggttca gggcttgttg cgtcgttcct
    22081 atgagtttgg gcgtgatgag agtttgctgg aatatgctgg tgttatcctc aataccaaat
    22141 ccatggattt acattatcaa gggcaagtct tgaatttgac caagaatgaa ttccagattt
    22201 tacgcgtgtt atttgagcat gcaggcaaca tcgtagcacg tgacgacctg atgcgggaac
    22261 tttggaacag tgactttttc attgatgata ataccctctc tgtcaatgtg gctcgtttgc
    22321 gtaaaaagtt ggaggagcag ggattggtag gatttatcga gaccaagaaa ggaatagggt
    22381 acggattgaa gcatgcttga ttggaaacaa ttttttctag cctatctgcg ctcccgtagt
    22441 cgtcttttta tctatctgct ttctttggca tttcttgtct tactctttca gtttttattt
    22501 gccagtctag gaatttactt cctctacttt ttcttcttgt gttgctttgt aaccatctta
    22561 tttttcactt gggacatatt ggtggaaacg caggtctatc gccaggaact tctctatgga
    22621 gagagggaag ccaagtctcc tttggaaata gctttagcag aaaaattaga agcgcgtgag
    22681 atggaactct atcagcagag gtcaaaagca gaaagaaaac tgacggattt gctggattac
    22741 tataccttgt gggtccatca gataaagacc cccattgcag ccagtcaact cttagttgca
    22801 gaagtggtcg accgccaact gaagcagcag ctagaacagg aaattttcaa aatcgactcc
    22861 tataccaacc tagttttaca gtacctgcgt ttagaaagtt tccatgatga tttgctctta
    22921 aagcaggttc aaattgagga cttggtcaag gaaataattc gtaaatatgc tcttttcttt
    22981 attcaaaaag gcttaaatgt caatctacat gaccttgata aagaaatcgt gacggataaa
    23041 aaatggctgc tagtggttat tgagcaaatc atctcaaaca gtctcaagta caccaaggaa
    23101 ggtggtctgg agatttatat ggatgaccaa gagctttgta tcaaagatac gggaatcggg
    23161 ataaaaaaca gtgatgtcct ccgagtattt gaacgtggct tttcaggata caatggccgt
    23221 ttgacccagc agtcctctgg acttggcctt tatctatcta agaaaatttc tgaagaactg
    23281 gggcaccaga ttcgtatcga gtctgaggtc ggaaaaggaa cgacagtgcg gattcagttt
    23341 gctcaagtga acttagtcct tgagtaaaaa tagatgagaa aaagcctcca gattggaggc
    23401 ttttatgcta gactcttatt tctcaacgcg tgatttgttg gcgatatcag ctaggatagc
    23461 ttgaacaaaa ttatcaactg agacagtttg tgtttctttt tggccgtagc gacgaacgtt
    23521 gactgtttcg tcttccattt ctttgtctcc aacaattaat tggtaaggaa tcttgctggt
    23581 ttgtgaagca cggatcttga actgcatttt ttcattgcgc tcatctacgt ctgcacggac
    23641 accgcggtca cggagtttct tggccacttc ccaagcgtag tccacgtgtt tttcgttaga
    23701 tactgggatg agggttactt ggtgtggtgc cagccatgtt gggaaggccc ccttgtagtt
    23761 ctcaatcaag atagctgtga agcgttccat agttgagata accccacggt ggatcatgac
    23821 tggacggtga tcttcgccat cagctccgat gtatttgagg tcgaagcgtt ctggcaacaa
    23881 gaaatcaagt tggatagtag aaagggtttc ttcttttcca agggcagttt taatctggat
    23941 atccaatttt ggtccgtaga aggctgcttc accttcggct tcaaagtagt ccacgcccat
    24001 ttcatcaaga gctgcacgaa gcatggtttg ggcattttcc cacatctcat cgttatcaaa
    24061 gtacttatga gtatcttgag ggtcacgaag agagaggcgg aagcggtagt cagtcaagtt
    24121 gaagtcttca taaacatcga taatcaactg aagggcacgt tggaattctt cttggatttg
    24181 ttctggagta acgaataggt gaccgtcgtt gagtgacatt tcacgtacac gttgaaggcc
    24241 agtgagggca ccagattttt cgtaacggtg catcataccg atttcagcga tacggattgg
    24301 caattcacgg taagagtgaa catggtgttt gaaaacttgg atgtggtgcg gacagttcat
    24361 tggacgaagg acaaattctt ccccgtcacc catgtccatg gttgggaaca tgtcttcttg
    24421 gtaatgatcc cagtgaccag aagtcttgta aagctcaaca gaagcaagtg gtggagtgta
    24481 gacgtgttgg tagccagaag ccaactcttt gtttacgatg tagcgttcca attcacgacg
    24541 gatagtcgca ccatttggca accagaacgg caaaccttgt cccacttctt gtgaaatcat
    24601 aaagaggtca agctctttac caagtttacg gtggtcacgt tccttagctt cttcacgcat
    24661 ttgaaggtag tttttcaagt ctttcttgtc aaaccaagct gtaccgtaga tacgttgcat
    24721 catagcgttg tcgctgtttc cacgccagta cgcaccagct acatggagaa ggtggaagat
    24781 ttggatacga cctgttgatg gaacgtgagg tccacggcag aggtctacat attcaccctg
    24841 acgatagata gtcaaaccgc cttcgtcttc tgagtgttct tcaatcaatt ccaacttgta
    24901 agggtcattt ttgaagattt cacgtgcctc gtctttagtc acttcttcac gaatagatgg
    24961 gaagttttct ttgacgattt tttgcatttc ttcttcgata cgaggaaggt cttcgttaga
    25021 gatttgacca gctgtgttgt cagtatcgta gtagaaacca tcttcgatgg ctggaccaac
    25081 tcccaagtga atgtccggga aaagacgacg agctgcttgg gcgaacaagt gagctgctga
    25141 gtgacgcaag attggaaggg catcttcgtg atcaggtgtc acaatttcga tgcttccatc
    25201 ttcagtgata gcgcgagtag tgtcgatgag tttgccgttg aatttaccag ccaaggcttt
    25261 tttagctagg gaattgctga tagattgggc aatttcaaaa gttgttacgc cagattcgaa
    25321 ttcacgaaca gcgccatctg ggaaagtaat gttaatcatg atgttctcct tttttattat
    25381 ttcatagttt ctaagcattg attttttatc agcagactac ttccgagtcc taacgttcaa
    25441 ttgcttttct ttatcagaga ggaagttttc catttccgtc agaatgtcta tatccaaacg
    25501 ttgagaaagt tctaatagcc accagatatt ttctgaaagt ttttgttcca gtgtgtaggg
    25561 tgtttcatca tagtagcgtc cttgctttgt catcaccagt cattggaaat ttccaatatc
    25621 attagataaa gccaagaggt cttcttctac cgtccacttg aaatcatgat gcttaacttc
    25681 cagttcgtga taagcttgtc ggattgccca actgcgctcc actaattctt gcaactccat
    25741 aattagtatc ctaataaaaa aatgcgacat cctcgaaagg acgtcgcaac gtggttccac
    25801 cttcatttat gtacctcaaa agagagggac acctctgatc ggctctaacg tggccaccgt
    25861 tttatgtttt cataaaaaac tcaagagtag tatcagttta gacttcctat gcgtttccag
    25921 caaccacgca ctctctagta gaaagggact aagtgacttg tctctatgga ttattatagc
    25981 atgattgtga gatttttcaa ggattttgtg aaagtttttt gtttttcatt ttttgtagaa
    26041 tatgcttgat gctaatacca gaatccatgc tcaccagagc aactgtttca tagattagca
    26101 agtaaattag tataaactca ccaaaggtta tgatagtaaa gtaaaagagc agtccgttac
    26161 caactaacca ccaaagtgag aaacggaaac ggtagctata gagtaacgat ataatcaaga
    26221 ttaccagagg tgtaaagaag agaagattgt ttatatagag tcccttgagt gtaagggggt
    26281 cagaaacaac tagcaagaac aactcataaa gtggccaata aaagaataat atgaccagat
    26341 agtaggggag atgggaatag aatctacgca tgataatcac ctcgttttaa aaaaacagac
    26401 aacttagatc tcttgctatg attattatag catgtttaaa acaagaaagt aaatttgttg
    26461 acaaagaaga tttttctttt ccctagaatc atagttagtt ttcttggtag aaatattttg
    26521 ataataatta agcaagacta ttgacattga ttattaagag tgtcacaatt gttgtaacta
    26581 aaataattac aacaagagag gtataaaaaa tgaaactagc agttattgca gcaaatggac
    26641 aagcggggaa ggcaattgtt gaagaagcag tcaaacgagg acatgaagta acggctattg
    26701 ttcgttctga aaacaaaagt caatctgagt ctattattaa aaaagattta tttgagttga
    26761 caaaagatga tcttactgga tttgatgctg ttatttcagc gtttggtgct tatacaccag
    26821 atacgctacc gctccacagc aaatcaatcg aactatttaa tcagcttctt gctggaacac
    26881 agacacgttt tctagttgta gggggatcag gaagctttta tatagatgaa acaaaaacga
    26941 cacgactttt agatacgtct gattttcctg aagaatttaa gccactagca aaagctcaag
    27001 cggatgaatt ggatcttctt cgtacaaaaa ataatctcaa ctggactttt gtcagtcctg
    27061 ctgtagattt tattcccgat ggtgaaaaaa caggaaacta cattctagca ggagaaattt
    27121 ttactactaa tgaaaaagga ataagccaga ttagttatgc agattatgct attggattgg
    27181 tagatgaact tgaaaaaggt catcatataa aagaacgtat ctctttactt gaaaaataat
    27241 aactatgaga gtattaatgt ttgacagaaa atttaaatct tggtagaata gggattgtcg
    27301 taaagacaaa taacttcttc ttggttacag gcatgccaac ctgtcactcg gatgaagcca
    27361 aataaaaagg agaaacatca tggcaatctc aaaagagaaa aaaaatgaaa tcatcgcaca
    27421 atatgcacgt cacgaaggtg atacaggttc agtagaggtt caagttgctg tccttacttg
    27481 ggaaatcaac caccttaatg aacacatcaa acaacacaaa aaagaccacg ctacttaccg
    27541 tggattgatg aaaaaaatcg gtcgccgtcg taacttgctt gcatacttgc gtaaaaacga
    27601 cgttaaccgt taccgtgagt tgatcaactc tctaggactt cgtcgctaat tcaagataca
    27661 aaggctgtca aaagcacaaa gtaaaaatag gaaaattgac gaagaaactt cagtttctag
    27721 gagattttat cttttttgcc aagtgcttag gccgtgttca attgagcata tcttgataat
    27781 gaagctactc taaattgggt agcttttttg tgttgtcacc ttacctcgat atactcaagt
    27841 ataatctttg gttacggttc ctagcactgt aaggtaaaat aaaccagctt ttctcccttc
    27901 ggggagattt tttttgtttc actgaaagtt tcgtacgatc ttcgcctcgt cgcctagtct
    27961 ataaacgatt tatctagcaa gaatcatgat gctaagggcg tcaaaaatcc gtatgaaaat
    28021 agggaaatga cacagtgttc gatgagcaca aggagtttca tctttttcac taggatttta
    28081 gcccggactc aaatcagctc tctgacttca gagggctttt ttattgaggt tttatcggta
    28141 acaattttgg agactacaaa aacctcaaac ggtatcagct aattacacca taaaggtgcg
    28201 cagttactcg gcttttcaag ccgagtagtt gtatgcaagc cccctagaag agcccactct
    28261 ttacaaagta aagtatagta tgttatactt tacatggaag tagtcactga attccagtta
    28321 gaaattactt tgtaactacg ttttgaggag gagtaaaatg ctttcctacg ttcgatatta
    28381 cccactagcg atagctaaat taatgtgtct gtgctctcct aaaatctgct gatttattac
    28441 tgactaatac aggagttttt tttatgggac agacaatcat atctgctatt ggtgtttata
    28501 tttccaccag tatcgattat ttaattattt taattatttt atttgcacag ctatcacaga
    28561 ataaacagaa atggcatatt tatgcggggc aatatctagg cacaggctta cttgtagggg
    28621 cgagtttagt tgctgcttat gtcgttaatt tcgtgcctga agaatggatg gttggattgc
    28681 ttggtttaat ccctatctat ttagggattc gctttgcaat tcttggagaa gatgcggaag
    28741 aagaagagga agaaattatt gaaagattag aacaaagcaa ggcaaatcaa ctgttttgga
    28801 cagttacatt gctgacaatt gcgtctggcg gagataattt aggtatctat ataccttatt
    28861 ttgcttcgtt agattggtca cagaccctcg tggccttgct tgtgtttgta atcggcataa
    28921 ttatcttttg cgagattagt cgggtgttat cctctattcc gttaatattc gagacaattg
    28981 aaaaatacga gcgaatcatt gtgcccttag tattcattct acttggacta tacatcatgt
    29041 atgaaaatgg cacgatagag acttttctga tcgtgtagat ttttttgttt cactaggatt
    29101 ttagcccgag ctcaaatcag ctctctgatt ttcagagggc tttttcattg agtataaatg
    29161 gacaatctta aagttactct attgtagagt ggcttttgat ttgattagga gattcttata
    29221 aatatagtaa aatgaaacaa aaacaggaca aatcgatcag gacagtcaaa tcgatttcta
    29281 aaaatgtttt aagaagtaga ggtgtactat tctagtttca atttgatata taaatgaaaa
    29341 ccttagctgt ttggccaagg ttcatttctt ctatgcaagt tcttctcttt tcttatctgg
    29401 gttccagatg aagcttgcga taaagctaaa gatgatggtt aggatagcga ggataatagc
    29461 aaggatgagg gcagggatgc ggataaacca ccagagtgga tttggttttt tatcattgtg
    29521 ccattgtttc gtttcttcgt ccagacgttg gaattctgtt tgaatacgat tggcgactgt
    29581 ttcaatgcct tcatcattca ttttcttgat atctgagata tcgattggat ttccaaagtt
    29641 catatcgaca cgttcacggc taatcaagcc cttcaaagtc atgggaccgg tgtaggtaac
    29701 cggcatgata cggactttgg ccattttggc aatcagtgct gcgcccccct tgacatcgtt
    29761 tgagtggcgg ctaccacttg gaaacatgat gagagagcgg tcactttttt tgagaacgtt
    29821 gataggatat ttgatggctg aggcgctggg attttcacgg tcgatgggaa aggcgccaca
    29881 catacgaatc caccaaccaa agatacggtt ggtaaagagt tctttttttg ccataaagat
    29941 gaactgtttt ggcttggtcg caaaggccat ataaacagga tcccaccagg tacggtgagg
    30001 cgcaactaaa atataatttt catcttgatt aggaatttta tcagtattat gatagtgagc
    30061 attgccattg atggaccata agagcaatac aactaatcca cgcaaataag tataaaacat
    30121 gcgatctcct tcgattgttt tcttgttatt attatacctt atcaaaggag ggctggcaaa
    30181 cttttccctt gactagatgc atatttggga tgaaattaga attttgttaa aaaaaatgat
    30241 ataatagaat ttatggataa aaataagatt atgggattaa cccaaagaga agtcaaggaa
    30301 agacaggctg agggtttggt caatgacttt accgcatcag ccagtaccag cacttggcaa
    30361 atcgttaaac gaaatgtctt tacccttttt aacgctttga acttagccat tgctttggct
    30421 cttgcctttg tgcaggcttg gagcaatctg gtcttctttg ctgttatctg ctttaacgct
    30481 ttttctggga ttgtgaccga gctacgagcc aaacacatgg tggacaagct caatctcatg
    30541 accaaggaaa aggtcaaaac catccgtgat ggtcaggaag ttgctcttaa tcctgaagaa
    30601 ttagtgctag gagatgtcat tcgtttgtct gcaggagagc agattcctag tgatgccttg
    30661 gttttggaag gctttgcgga agtcaatgaa gccatgttaa cgggagaaag tgatttggtg
    30721 caaaaggaag ttgacggctt acttttgtca ggaagtttcc tagccagtgg gtcagtttta
    30781 tctcaagttc accatgtcgg tgcagacaac tatgctgcca aactcatgct tgaggctaag
    30841 accgttaaac ccatcaactc ccgtatcatg aaatcgctgg acaagttggc tggttttact
    30901 gggaagatta tcattccctt tggtctggct ctcttgctgg aagccttgct tttaaaaggc
    30961 ctgcctctca agtcatctgt tgtaaactcg tcgacagctc ttttgggaat gttgcctaag
    31021 ggaattgccc ttttgaccat tacttcgctc ttgactgcag tgattaagtt gggcttgaaa
    31081 aaggtcttgg tgcaggagat gtactctgtt gagaccttgg cgcgcgtgga tatgctctgt
    31141 ctggacaaga cgggcaccat cacccaagga aagatgcagg tggaggctgt tcttccactg
    31201 acggaaactt acggtgaaga ggctattgcc agcatcttga ctagctacat ggcccatagt
    31261 gaggataaga atccaactgc ccaagccatt cgccagcgtt ttgtgggaga tgttgcttat
    31321 cctatgattt ccaatcttcc cttctccagc gaccgcaagt ggggggctat ggagttagaa
    31381 ggcttgggga cagttttctt aggggcacct gagatgttgc tggattctga agtcccagaa
    31441 gccagggagg ccttggagag aggatcacgt gtcttggtct tagctctcag tcaggagaaa
    31501 ttagaccatc acaaaccaca gaaaccatct gatattcagg ctctagcctt gctggaaatc
    31561 ttggacccca ttcgagaggg agcagcagag acgctggact atctccgttc tcaggaggtg
    31621 ggactcaaga ttatctctgg tgacaatcca gttacggtgt ccagcattgc ccagaaggct
    31681 ggttttgcgg actatcacag ctatgtagat tgctcaaaaa tcaccgatga ggaattgatg
    31741 gccatggcgg aggagacagc tattttcgga cgtgtttccc ctcatcaaaa gaaactcatc
    31801 atccaaacgt tgaaaaaagc gggtcataca acggctatga caggggacgg ggttaatgat
    31861 atcttggccc ttcgtgaggc ggattgttct atcgtgatgg cggaggggga tccagcaacc
    31921 cgtcagattg ccaatctggt tctcttgaac tcagacttta atgatgttcc tgagattctc
    31981 ttcgagggtc gtcgcgtggt caataacatt gcccacatcg ccccgatttt cttgataaag
    32041 accatctatt ccttcctgtt agcagtcatc tgtattgcca gtgctttact aggtcggtct
    32101 gaatggatct tgattttccc cttcattcca atccagatta ccatgattga ccagtttgtg
    32161 gaaggtttcc caccattcgt tctgactttt gagcgaaata tcaaacctgt tgagcagaat
    32221 ttcctcagaa aatccatgct tcgtgcccta ccaagcgctc tcatggtcgt ctttagcgtc
    32281 ctgtttgtga aaatatttgg gagtagccaa ggttggtctg agttagaaat ctcaactctc
    32341 ctctattatc tcttggggtc aattggtttc ttatccgtat ttagagcctg catgccattt
    32401 accctatggc gtgtcctctt gattgtttgg tcagtaggag gtttcctagc cacagctctc
    32461 ttcccaagaa tccaaaaact gcttgaaatt tcaaccttga cagaacaaac gttgcctgtt
    32521 tatggtgtca tgatgttggt ctttacagtg attttcatcc tgactagtcg ctatcaagct
    32581 agaaaataaa gaaagactgc aatctgtgga ttgcagtttt tttaggtaca agattgccag
    32641 ccgaaatgtg gtataataag aggtaataga gttttggaaa gtgagagaag atgatttcaa
    32701 agagattaga attggtagct tcctttgtgt cacagggggc tattttacta gatgtgggaa
    32761 gtgaccatgc ttatctgcct atcgagttgg ttgagagagg ccaaatcaaa agcgctattg
    32821 caggtgaggt ggtggaaggt ccctatcagt ctgcggttaa aaatgttgag gctcacggcc
    32881 taaaggagaa aatccaagtc cgtttagcca atggcttggc agcttttgaa gagactgacc
    32941 aagtgtctgt cattaccatt gctggcatgg gtggtcgttt gattgctagg attttagaag
    33001 aaggtttggg gaagttagct aatgtagagc gtttgatcct ccagcccaat aatcgtgaag
    33061 acgacttgcg tatctggcta caggatcatg gattccagat tgtagcagaa agcatcttag
    33121 aagaagctgg aaagttttat gagattttgg tggtggaagc aggacaaatg aagctatcag
    33181 ccagtgatgt tcgctttggt cccttcttgt ccaaagaagt cagtccagta tttgtccaaa
    33241 aatggcaaaa agaagctgag aagctagagt tcgccctcgg acaaatccca gaaaaaaatc
    33301 tggaagaacg tcaagttcta gtagataaga ttcaagctat caaggaggtg ctccatgtta
    33361 gcaagtgaag tgatccaagc ttatgaagcc ttttgccctc aggaattttc tatggaggga
    33421 gacagccgtg gtctgcaaat tggcacttta gacaagggta tccaaagggt catggttgcc
    33481 ctcgatattc gtgaagagac agtggcagag gccattgaaa agggtgtgga cttgattatc
    33541 gtcaagcacg cgcctatctt tcgtcctatc aaggacttgc ttgccagccg tccgcaaaat
    33601 cagatttaca tcgacctgat taagcatgat atcgcagttt atgtcagcca taccaatatt
    33661 gatatcgttg aaaatgggct caatgactgg ttttgtcaga tgctaggaat cgaggagacg
    33721 acttatctgc aggaaacagg tccagaacgt ggaattggac gtattgggaa tattcagcct
    33781 cagacatttt gggaattggc ccaacaggtc aagcaagtct ttgacctaga tagccttcga
    33841 atggtgcatt atcaagagga tgatttgcag aagcctattt caagagtagc aatttgtggt
    33901 ggaagcgggc agtctttcta taaggatgct ttggcaaagg gggcagatgt ctatatcact
    33961 ggtgatatct actaccatac tgctcaggat atgctgtctg atggcttgtt agcattggat
    34021 ccaggtcact atatcgaagt gctttttgtg gaaaaaatcg caacactcct tactcaatgg
    34081 aaagagaaaa aaggctggga actagagatt ttacctagtc aagcatcgac caatcctttc
    34141 cgtcatatct agttagaaag tgaagacaat gaaaaaagtt gccattattg gagcaggaat
    34201 tgtgggagca acagctgcct actacctctc gagagaaagt gacctagagg tgaccgtttt
    34261 tgaccatgag caaggtcaag ccaccaaggc cgcagcagga attatcagtc cttggttttc
    34321 caaacgccgt aataaagcct ggtacaagat ggcgcgcttg ggggctgatt tttatgtgga
    34381 tttattagct gatttagaga aatcaggaca agaaatcgac ttttaccagc gttcgggagt
    34441 ctttctcttg aaaaaggatg aatccaattt ggaagaactt tatcaactgg ccctccagcg
    34501 cagagaagaa tctcccttga tagggcaatt agccattctg aaccaagcct cagctaatga
    34561 attattccct ggtttgcagg gatttgaccg cctgctctat gcttctggtg gagcgagagt
    34621 agatggccaa cttttagtga ctcgtttgct ggaagtcagt catgtcaagc tggtcaaaga
    34681 aaaagtgact ctgacaccgt tagcatcagg ctaccagatt ggtgaagagg agtttgagca
    34741 ggttattttg gcgacgggag cttggttggg ggacatgtta gagcctttag gttatgaagt
    34801 ggatgttcgt cctcaaaaag gacaactacg agattatcag cttgcccaag acatggaaga
    34861 ttaccctgtt gtcatgccag aaggggagtg ggatttgatt ccctttgcag gtgggaaatt
    34921 atccttaggc gctacccacg aaaatgacat gggatttgat ttgacggtag atgaaacctt
    34981 gctccaacaa atggaggagg ccaccttgac tcactatctg attttggctg aagctacttc
    35041 aaaatctgag cgtgttggaa tccgtgccta caccagtgat ttctctcctt tctttgggca
    35101 ggtgcctgac ttaactggtg tctatgcagc cagtggacta ggttcatcag gcctcacaac
    35161 tggtcctatc attggttacc atctagccca actgatccaa gacaaggagt tgaccttgga
    35221 ccctctaaat tacccaattg aaaactatgt caaacgagta aaaagcgaat aatactcaat
    35281 aaaaatcaaa gaacaaacta ggaaactagc cgcgggttac tcaaagcact gctttgaggt
    35341 tgtggataga actgatgaag tcagtaacca tacccatggc aaggcgacgt tgacatggtt
    35401 tgaattggat tttcgaagag tataagcatt ttactgaaat tttatcaggt agtttaggat
    35461 ggcaaatgac attccctgtc aaaaatggta aaataagaaa aaataatctg agaatcgagg
    35521 aaaaaagatg caagaaaaga ttttggtaac tggtggtgcc ggttttattg gaacccacac
    35581 tgttattgaa ttgatccaag caggccatca agttgttgtg gtggataatc ttgtcaatag
    35641 caatcgtaag agtttagaag ttgttgaaag aatcacagga gttgagattc ctttctatga
    35701 ggcagatatt cgtgacacag ataccctcag agatattttc aagcaggaag aaccgactgg
    35761 tatcattcac tttgctggtt tgaaggctgt tggcgaatca acacgtatcc ctcttgccta
    35821 ctatgacaac aatatcgctg gaactgtcag ccttttgaaa gccatggaag aaaacaactg
    35881 taaaaacatc atcttcagtt cttctgcgac agtttacggg gatccgcaca cagtgcccat
    35941 cttggaagat ttcccacttt cagtgaccaa cccatacggt cgtactaagc tcatgctaga
    36001 ggaaattttg actgatattt acaaagcaga ctcagaatgg aatgttgtct tgcttcgtta
    36061 ctttaaccca atcggagccc atgagagtgg tgatttggga gaaaatccaa acggtattcc
    36121 aaacaatctc ttgccatatg tgactcaagt agccgttgga aaattagagc aagtgcaagt
    36181 gtttggagac gattacgata cggaagatgg aacaggtgtt cgtgactata tccacgttgt
    36241 cgatttggct aagggtcacg ttgcagcttt gaaaaaaatc caaaaaggtt caggactaaa
    36301 cgtttataac cttggaactg gtaaaggtta ctcagttctt gaaattatcc aaaacatgga
    36361 aaaagcggtg ggccgtccta ttccttaccg catcgtagaa cgtcgcccag gtgatatcgc
    36421 tgcctgctac tcagacccag caaaggctaa agcagaactc ggttgggaag cagaactcga
    36481 catcacccaa atgtgtgaag acgcatggcg ttggcaaagc aagcatccaa atggatttga
    36541 agactaagat gatgatttca atcatcgtcc cttgtttaaa cgaagaggaa gtacttcctc
    36601 ttttttatca ggctctggaa gctttacttc cagatttgga aacagaaatc gagtatgtct
    36661 ttgtcgatga tggatcaagt gatgggacct tggaactctt aaaggcctat cgggagcaaa
    36721 atccggcagt ccattatatt tctttctctc gaaattttgg caaagaagca gccctttatg
    36781 caggcttgca atatgcgaca ggagatttgg tggtggtgat ggatgcagac ctccaagatc
    36841 ctcctagtat gttgtttgag atgaaaaatg tactagacaa aaatgtagac ttggactgcg
    36901 ttgggacacg gagaactagt cgggagggag aacccttctt tcgcagtttc tgtgctgttc
    36961 tcttttatcg cctcatgcaa aaaatcagcc cagtagctct gccgtcgggt gtccgtgatt
    37021 ttcgtatgat gagaaggtct gtagtcgatg ccattttaag cttgaccgag tccaatcgtt
    37081 tttcaaaggg gctcttcgcc tgggtgggtt tcaaaaccta ctatttggac tatccaaatg
    37141 tcgaaaggca ggctggcaag acaagttgga gttttaggca actctttttc tactccattg
    37201 aagggattat taatttttca gatttccctt tgactatagc ctttgtagct ggtctcctat
    37261 cttgttttct ttctctgctg atgacctttt ttgttgtggt tcggaccctc attttgggca
    37321 atccgacatc tggttggacc tctctgatgg ctgttattct ctttcttgga ggcattcaac
    37381 tcttgaccat tgggattctc ggtaagtata tcagtaagat ttatttagag actaaaaaaa
    37441 gaccacttta tcttatcaaa gaaaaaagtg accttcctga ttttacagaa aaaaataaag
    37501 tgaaaagact ataattttac atggaaatgt gctaaactag agggagtgga ttatcgccat
    37561 tgatttaggc ttcctggttt ccaatcaggg cgcgagttgg gcaattttta acagcctcta
    37621 agacatcctg actaggagaa atttcttttt ccagttggtc agggccatcg taaaaacgca
    37681 cgattccatt atcgtggtaa tcaaataaat cagaataagt ttggcaaagc ccacaggcga
    37741 tacatcgttc aggtataagt gtgattttca tgttcatatt tatattgtaa taagaaaagt
    37801 aaaaaaaaac aaggagtaag gtatggcaaa agaaccgtgg caagaagata tctatgatca
    37861 agaagaatca agagcagggc gtcggcatcg aaaccacgga ggggctgata ggatggctaa
    37921 tcgtattttg acgatcctag ctagtatttt ctttgtaatt gtggtggtga tggtcatcgt
    37981 tctcatctat ctatcatcgg ggggaagtaa tcgcacagca gccttaaaag actttcatga
    38041 ttctgatgca agtgtagtac aaatctcatc ttcaagcagt tctcatcctg agcagagttc
    38101 agagccagaa tctacttcta gtagttcaga agaagctgct aatcctgaag gaacgattaa
    38161 agttctcgca ggagaagggg aagcagctat tgccgctcgt gcaggaatct ccattgctca
    38221 gttagaggcc ttgaatcctg ggcacatggc tacaggatct tggtttgcta atccaggtga
    38281 tgttataaaa ataaaatagg agccgatatg aaaacaattc aaattgctat tgatggtcct
    38341 gcttccagcg gtaagagtac ggtcgcaaag attattgcta aggattttgg attcacctac
    38401 cttgatacag gagctatgta tcgtgcagcg acctatatgg ctcttaagaa ccaattagga
    38461 gttgaagaag tcgaagccct tctagccttg ttggaccagc atccaatcag ctttggacgt
    38521 tcagaaactg gagaccagct tgtttttgta ggagatgtgg atattaccca tcctatccgt
    38581 gaaaatgaag tgaccaatca tgtttctgct attgcagcaa ttcctgaagt gcgtgagaaa
    38641 ctggtttctc tccaacaaga aattgcccag caaggcggga ttgtcatgga tggtcgcgat
    38701 attggaactg ttgtattgcc acaagcagaa ttgaaaattt tcctagtagc ttctgttgat
    38761 gagagagcag agcgtcgtta caaggaaaat attgccaagg gaattgaaac agaccttgaa
    38821 accctaaaaa aggaaattgc tgcgcgtgac tacaaggata gtcatcgtga gacttctcct
    38881 ctcaaacaag cagaggatgc tgtctacctt gatacaactg gtttgaacat tcaagaagta
    38941 gttgaaaaaa tcaaagcaga agctgaaaaa agaatgtaaa tgtagaaaag ccgatagatt
    39001 gatatcggtt tttttctaaa tttgtcaaaa tgctgatttt agggtataat agttgctgtt
    39061 cgagaaattt tgattttcaa agaatagtga atgatgataa ggagaaacca tgaacaattt
    39121 accaaattgt ccaaaatgta actcagagta tgtctacgaa gacggtgccc tactggtttg
    39181 cccagagtgt gctcatgagt ggaatcctgc tgaagttgca gaagtagaag aaggtcttgt
    39241 cgctatcgat gccaacggaa ataaattgac tgatggtgat acagtaactc tcatcaagga
    39301 cttgaaagta aaaggtgcgc caaaagattt gaaacaaggg acgcgcgtga aaaatatccg
    39361 catcgtagaa ggcgatcaca atatcgactg taagattgat ggttttggtg ccatgaaact
    39421 taaatcagag tttgtgagga agatttaagc atgtcaaaac actataaact tgtattttat
    39481 agccgtatct tcttgtttct agcggctttt acgggagttt atcttgaaat tactaggcat
    39541 ggtggttttg ggatgcttct ctattacacg gttctgtcca acctcttggt aactattttt
    39601 accctttatc ttctaaaggt tatgagccgt gtaggtgaaa attggcaaag gccaagtctc
    39661 ttgcgcttaa aaggtggggt caccatgagt atcatgatta cctgtgtgat ttaccatttc
    39721 ctcttggcgc ccattgcgac taatttctat accctagaaa atttcctttg ccactatatc
    39781 gttcccatct ggtttttagc ggataccctc ttttttgaca aacagggtca atacaagatt
    39841 tgggatccag cagtgtggac cattttaccc tttctgtata tgatgtttgc tctttttaat
    39901 ggcttggttc taaaactcaa tattccaaat gccaaggata atcctttccc ttacttcttt
    39961 ttgaatgtga acaagggttg gaatgttgtg tttaagtggt gtctgattat ctttgttgcc
    40021 tatatggtag caggatttat tttctacttt atcaagcaaa tcaagagaaa gtcatcctaa
    40081 tactcttcga aaatctcttc aaaccacgtt agtttccatc tgcaacctca aaacactgtt
    40141 ttgaacaacc tgcggctagc tttctagttt gctctttgat tttcattgag tatgagatac
    40201 aagggattca ttttcgaatt taagaaggag tctacaaacc aatgaggctt cttcttttct
    40261 tgcttatttg ataactatca aaaaagtaga agattaagag aaatatagaa agagatttca
    40321 tgaaacaatt tttagaacgg gccagcattt tggctctctc cctcgttttg attacctcct
    40381 tttccatttc gagtgcccta ccagccatgt ttgactatta tcagggttat tctaaggaac
    40441 aaattgagct cttggtgagc ttgccttcct ttggaatcat gatgatgtta ctgctaaatg
    40501 gtttcttaga aaaaatattt cctgagcgct tacagattag tttgggcttg ctgattttat
    40561 cattgagcgg tacagctccc ttctggtacc aagcctatcc ctttgtcttt ggaacacggc
    40621 ttctctttgg tttgggtctt gggatgatca atgccaaggc catttctatt atcagtgaac
    40681 gctaccaagg aaaaaggcga attcagatgt tagggctacg cgcttctgca gaggtcgttg
    40741 gagcttctct cattaccttg gccgtcggtc agttgttggc ctttggttgg acagctatct
    40801 ttctagccta tagtgctgga tttttggtga tgccccttta tctgctcttt gtcccttatg
    40861 gaaaatcaaa gaaagaagtc aagaaaagag cgaaggaagc aagtcgttta actcgagaaa
    40921 tgaaaggctt gatttttacc ttagctatcg aagcggcagt tgtagtttgt accaatacag
    40981 ctattaccat ccgtattcca agtttgatgg tggaaagagg attgggggat gcccagttat
    41041 ctagttttgt tcttagtatc atgcagttga tcgggattgt ggctggggtg agtttttctt
    41101 tcttgatttc tatctttaaa gagaaactgc tcctctggtc tggtattacc tttggcttgg
    41161 ggcaaatcgt gattgccttg tcttcatcct tgtgggtggt agtagcagga agtgttctgg
    41221 ctggatttgc ctatagtgta gtcttgacga cggtctttca acttgtctct gaacgaattc
    41281 cagctaaact cctcaatcaa gcaacttcat ttgctgtatt aggctgtagt ttcggagcct
    41341 ttacgacccc atttgttcta ggtgcaattg gcttactaac tcacaatggg atgttggtct
    41401 ttagtatctt aggaggttgg ttgattgtaa tctctatctt tgtcatgtac ctacttcaga
    41461 agagagctta ggattgattc ctaagttttt cttttgatac tcaatgaaaa tcaaagagca
    41521 tagttgattg agtttggaat agtacgctgt agctgctaaa atatttctag aaattaattt
    41581 gacttttcta atagagttat tcatatctta tttcaatcta ctatagaaag ctagccgcag
    41641 gttgctcaaa atagtgtttt gaggttgcag atggaaactg acgtggtttg aagagatttt
    41701 cgaagagtat gagattttta tacccataca atatttgttt taggtccttg tttacagact
    41761 aatttcttga taaaatagag gttatgacga gatataaagc aactatttcc tatgatggtt
    41821 atgcctttgc tggctttcag cgccagtctc atgcgcgtag cgttcaggaa gaaattgaaa
    41881 aaaccttgac cagattaaat aaagggcaaa ccattactgt tcacggtgct ggtaggacag
    41941 atagtggggt tcatgccctg ggacaggtca ttcattttga cctgccttat cagatggatg
    42001 aggagaaact ccgttttgcc ttggataccc agtctcctga agatattgat gtgatttcga
    42061 ttgagcttgt ggcagatgat tttcattgcc gttatgccaa acatagcaag acctatgagt
    42121 ttattgtgga tagaggacgt cccaaaaatc ctatgcgccg tcactatgcc acccactttc
    42181 cctacccact cgatgtggaa cgaatgcaga ttgcaatcaa aaagctagag ggaacccatg
    42241 attttaccgg ttttacagcc tctgggacta gtgtagagga taaggttcgc accatcacag
    42301 aagctagttt aatagtcgat gagacaggac aatttttgac ctttaccttt tcaggaaatg
    42361 gtttcttgta taaacagatt cgcaatatgg tggggactct tctcaaaatc ggtaacaacc
    42421 gcatgccagt agagcagatt gatctcatct tggagaagaa ggacaggcaa cttgcaggtc
    42481 ccactgcagc accaaatggt ttgtatttaa aggagattcg ttatgaagaa taatcgtatt
    42541 ttagcacttt ctggaaatga tatttttagt ggtggtggac tgtcagctga tttggctacc
    42601 tataccttga acggcttgca tgggtttgta gcagtgactt gtttgacagc cttgacagaa
    42661 aaaggatttg aagtctttcc aactgatgat accatttttc aacatgaatt agatagctta
    42721 cgtgatgtgg aatttggggg aattaagatt ggtcttctcc ctactgtcag tgtggctgag
    42781 aaggccttgg actttatcaa acaacgccca ggagtacctg tggtgttgga tcctgtcttg
    42841 gtctgcaagg aaacgcatga tgtagctgtc agtgagctct gccaagagtt gattcgcttt
    42901 ttcccttatg tcagtgtgat tacgcctaat ctcccagaag cagaattatt atccggtcag
    42961 gaaattaaaa ccttggaaga catgaaaact gcagcgcaga aattgcatga tttaggagcg
    43021 ccagcagtca ttatcaaggg aggcaatcgt cttagtcagg acaaggctgt ggatgtcttt
    43081 tatgatggac agacctttac tatcctagaa aatccagtta tccaaggcca aaatgttggt
    43141 gcaggttgta cctttgcctc tagcattgcc agtcacttga ttaaaggtga taaacttttg
    43201 ccagcagtag aaagctctaa ggctttcgtt tatcgtgcta ttgcacaagc agatcagtat
    43261 ggagtaagac aatatgaagc aaacaaaaac aactaaaatc gcccttgtat ccctattaac
    43321 cgccctttct gtggttctag gttatttctt aaaaatccca acacctacag gaattctaac
    43381 tcttttagat gctggtgtct tctttgcggc cttttacttt ggtagtcgtg aaggagcggt
    43441 agtcggagga ctagcaagtt tcttgattga cctcttatca ggctaccctc agtggatgtt
    43501 ctttagcttg gtcaaccatg gcttgcaggg atttttcgca ggatttaaag gaaaaagtca
    43561 gtggttaggc cttattttag caactattgc catggtagga ggctacgcct tgggttctac
    43621 tttgatgaat gactgggcag cagccctccc agaaattcta ccaaatttta tgcaaaatat
    43681 ggtagggatg attgtaggat ttattcttag tcaaagtatc aagaagatta agtaatactc
    43741 ttcgaaaatc tcttcaaacc acgtcagctt ccatctgcaa cctcaaaaca ctgttttgag
    43801 cagcctgagg ctagctttct agtttgcact ttgattttca ttgagtataa agaggttgag
    43861 taaaaagtct ttcaaataag aaaaacgcat agtatcaggt gttgaatgaa ctgcccccca
    43921 aaagttagac agaaaaaatc taacttttgg ggtgttttat tatgaaa
//
LOCUS       DAVDHZ010000012        41645 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000012 DAVDHZ010000000
VERSION     DAVDHZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.012"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            249..770
                     /gene="pyrR"
                     /locus_tag="VUR46_000849"
     CDS             249..770
                     /gene="pyrR"
                     /locus_tag="VUR46_000849"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET5456305.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVADREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            789..1712
                     /locus_tag="VUR46_000850"
     CDS             789..1712
                     /locus_tag="VUR46_000850"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET5456306.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPCEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIVNGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            1762..2841
                     /gene="carA"
                     /locus_tag="VUR46_000851"
     CDS             1762..2841
                     /gene="carA"
                     /locus_tag="VUR46_000851"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET5456307.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            3154..6330
                     /gene="carB"
                     /locus_tag="VUR46_000852"
     CDS             3154..6330
                     /gene="carB"
                     /locus_tag="VUR46_000852"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET5456308.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAIEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLETGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGLENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(6605..7414)
                     /locus_tag="VUR46_000853"
     CDS             complement(6605..7414)
                     /locus_tag="VUR46_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5456309.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(7416..8219)
                     /locus_tag="VUR46_000854"
     CDS             complement(7416..8219)
                     /locus_tag="VUR46_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5456310.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSHENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(8229..9716)
                     /gene="tacF"
                     /locus_tag="VUR46_000855"
     CDS             complement(8229..9716)
                     /gene="tacF"
                     /locus_tag="VUR46_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET5456311.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRAFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVLPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            10052..10759
                     /locus_tag="VUR46_000856"
     CDS             10052..10759
                     /locus_tag="VUR46_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET5456312.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            10764..11786
                     /locus_tag="VUR46_000857"
     CDS             10764..11786
                     /locus_tag="VUR46_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET5456313.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            11803..12672
                     /gene="licA"
                     /locus_tag="VUR46_000858"
     CDS             11803..12672
                     /gene="licA"
                     /locus_tag="VUR46_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET5456314.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            12662..13540
                     /locus_tag="VUR46_000859"
     CDS             12662..13540
                     /locus_tag="VUR46_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET5456315.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRVSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            13552..14241
                     /locus_tag="VUR46_000860"
     CDS             13552..14241
                     /locus_tag="VUR46_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET5456316.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            14338..15186
                     /gene="dprA"
                     /locus_tag="VUR46_000861"
     CDS             14338..15186
                     /gene="dprA"
                     /locus_tag="VUR46_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET5456317.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            16070..17113
                     /locus_tag="VUR46_000862"
     CDS             16070..17113
                     /locus_tag="VUR46_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET5456318.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGMGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            17280..19367
                     /gene="topA"
                     /locus_tag="VUR46_000863"
     CDS             17280..19367
                     /gene="topA"
                     /locus_tag="VUR46_000863"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET5456319.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            19473..19832
                     /locus_tag="VUR46_000864"
     CDS             19473..19832
                     /locus_tag="VUR46_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET5456320.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            19925..20557
                     /locus_tag="VUR46_000865"
     CDS             19925..20557
                     /locus_tag="VUR46_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET5456321.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            20601..21257
                     /locus_tag="VUR46_000866"
     CDS             20601..21257
                     /locus_tag="VUR46_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET5456322.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            21276..21908
                     /locus_tag="VUR46_000867"
     CDS             21276..21908
                     /locus_tag="VUR46_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET5456323.1"
                     /translation="MNFQLAKYSLLKKFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGELSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            21936..22370
                     /locus_tag="VUR46_000868"
     CDS             21936..22370
                     /locus_tag="VUR46_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HET5456324.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            22382..23419
                     /gene="leuB"
                     /locus_tag="VUR46_000869"
     CDS             22382..23419
                     /gene="leuB"
                     /locus_tag="VUR46_000869"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET5456325.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDTERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            23416..23685
                     /locus_tag="VUR46_000870"
     CDS             23416..23685
                     /locus_tag="VUR46_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET5456326.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            23689..24048
                     /gene="leuD"
                     /locus_tag="VUR46_000871"
     CDS             23689..24048
                     /gene="leuD"
                     /locus_tag="VUR46_000871"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET5456327.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            24210..24780
                     /locus_tag="VUR46_000872"
                     /pseudo
     CDS             24210..24780
                     /locus_tag="VUR46_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            24874..24939
                     /locus_tag="VUR46_000873"
                     /pseudo
     CDS             24874..24939
                     /locus_tag="VUR46_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            25102..27015
                     /locus_tag="VUR46_000874"
     CDS             25102..27015
                     /locus_tag="VUR46_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET5456328.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            27002..28318
                     /locus_tag="VUR46_000875"
     CDS             27002..28318
                     /locus_tag="VUR46_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET5456329.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKILHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYVTREFTYDNPLMQLVRYTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            28493..29479
                     /locus_tag="VUR46_000876"
     CDS             28493..29479
                     /locus_tag="VUR46_000876"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET5456330.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            29543..29614
                     /locus_tag="VUR46_000877"
     tRNA            29543..29614
                     /locus_tag="VUR46_000877"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29576..29578,aa:Arg,seq:ccg)
     gene            29797..30495
                     /locus_tag="VUR46_000878"
     CDS             29797..30495
                     /locus_tag="VUR46_000878"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET5456331.1"
                     /translation="MKELQTVLKNHFAIEFTDKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            30486..34025
                     /gene="smc"
                     /locus_tag="VUR46_000879"
     CDS             30486..34025
                     /gene="smc"
                     /locus_tag="VUR46_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET5456332.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEATLKTLQDQMARLSELLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELDRLSDGDWQADKEKCQDRLATIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            34022..34816
                     /locus_tag="VUR46_000880"
     CDS             34022..34816
                     /locus_tag="VUR46_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5456333.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            34816..35634
                     /locus_tag="VUR46_000881"
     CDS             34816..35634
                     /locus_tag="VUR46_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5456334.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSNQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            35638..36927
                     /gene="ftsY"
                     /locus_tag="VUR46_000882"
     CDS             35638..36927
                     /gene="ftsY"
                     /locus_tag="VUR46_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET5456335.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDIEPAFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(36973..38460)
                     /locus_tag="VUR46_000883"
     CDS             complement(36973..38460)
                     /locus_tag="VUR46_000883"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET5456336.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(38609..39349)
                     /locus_tag="VUR46_000884"
     CDS             complement(38609..39349)
                     /locus_tag="VUR46_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5456337.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(39349..41514)
                     /locus_tag="VUR46_000885"
     CDS             complement(39349..41514)
                     /locus_tag="VUR46_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET5456338.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRIISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT        12900 a         7469 c         9026 g        12250 t
ORIGIN      
        1 accagtaccc acaattatat gattttagca atttgtaaga tgctacattg aaactttttg
       61 cttgatttta agcatgcttt gtgctatagt aaatgataac taaatattcc tttaaacctg
      121 tcccgtgagg caggcaagga gcgcgataaa gtagaagggt gaagtctata ctgtgtgcag
      181 tagggctcgc ttggctataa atttcaagtc tccttgttta aggagacttt tctttttgga
      241 ggtttgtcat gaaaacaaaa gaagttgtag acgaattgac cgtcaaacga gcgattacgc
      301 gtattactta tgagattatc gaacgcaaca aagatttgaa taagatcgtc ttggctggta
      361 ttaaaactcg tggtgtcttt attgcccacc gaatccaaga acgtttgaag cagttagaaa
      421 atctttcagt tcctgttgtg gaattggata ctaaaccttt ccgtgatgat gttaaaagtg
      481 gagaagatac ttctttggtt tctgtcgatg tggcagaccg cgaagttatc ttggtggatg
      541 atgtgctcta tacaggtcgt accatccgtg ctgctattga taatattgtc ggtcatggtc
      601 gtcctgcgcg tgtgagttta gcagttctag tcgatcgtgg acatagagaa ttgccaatcc
      661 gtccagatta cgttggaaaa aatatcccaa ccagtcgttc tgaagaaatc atcgtagaga
      721 tgacagaact tgatgaccaa gacagagttc tgattactga agaagcttag aaagttaaag
      781 gagtagccat gtcagaaaat caacaagcat tgaaccatgt ggtgtccatg gaagacctca
      841 ctgtcgatca agtgatgaaa ttgatcaagc gaggaattga gtttaaaaat ggagcccagc
      901 ttccctgtga agaccatccg attgtttcca atctcttctt tgaggattct acacggacac
      961 ataagtcctt tgaagtcgca gagattaaac ttggattgga acgccttgac tttgatgtga
     1021 agactagttc ggttaataag ggtgagacac tttatgacac cattttgact ctgtctgctt
     1081 taggagtgga tgtctgtgtg attcgccatc cagaggtcga ctactataga gaattgattg
     1141 ctagtccaac gattacgact tccatcgtca atggtggaga tggttcgggc caacacccta
     1201 gccagagctt gcttgatttg atgaccattt atgaggaatt tggccacttt gagggtctta
     1261 aagttgctat tgcaggtgac ttggatcact cacgcgttgc caaatccaat atgcagattt
     1321 tgaaacgctt gggagctgaa ctctttttcg ctggacctga ggaatggaga agtcaagagt
     1381 ttgcagacta tggacagttt gtaaccattg atgaaatcat tgatcaggtt gatgtcatga
     1441 tgtttctccg tgtgcaacac gaacgccatg atagtggagc tgtattttca aaagaagact
     1501 accatgccca acatggcttg actcaagaac gttacgatcg tttgaaagaa acagcaatcc
     1561 tcatgcaccc agctccaatc aatcgtgatg tagaaatagc agaccacttg gttgaagcac
     1621 caaaatcacg gattgtccaa caaatgacca atggtgtctt tgttcgaatg gcaatcttag
     1681 aatccgtact agcgagtaga aacgccaact aaaacacaag acgttaaaag acgccagtga
     1741 gcgtccacga gaggtgaaaa tatgacaaaa agaattctag tattagaaga tggcacagtt
     1801 tttgaaggca aggccttcgg agcagatatt gatgtaacag gcgaaatcgt ctttaataca
     1861 ggaatgaccg gctaccaaga atccattaca gaccagtctt ataatggaca aatcttgacc
     1921 tttacttatc ctttggtagg aaattatggt attaatcgtg atgattatga atccattatt
     1981 ccaacttgta agggagtcgt tgtttttgaa gaagcgcgta gagctagcaa ctggcgcaac
     2041 caaatgacct tggatgaatt tttgaaagcc aagaaaattc cagggatttc aggaattgat
     2101 acgcgtgctc ttaccaagat tatccgtaag catggtacta tgcgtgcaac cttgacccat
     2161 gttggggaca gtatggacca tgtgacggac cagctccaag caacagtttt accgacagac
     2221 aatatcaaac aggtttctac taaaacgtct tatccagctc caggagttgg tttgagcgtg
     2281 gtgctagtgg actttggtct caagcactca atcctacgtg aactttctaa acgcaactgt
     2341 aacgtgacag ttgttcctta ttcgacaacg gctgaagaaa ttctccatct caatcctgac
     2401 ggagttatgt tgtcaaatgg tccaggtaac ccagaagacg ttccacaagc actcgacatg
     2461 attcgcggtg tacaaggaaa aataccaatc tttggtattt gtatgggaca ccaactcttt
     2521 gcaatggcaa acggggctaa gacctataag atgaagtttg gccaccgtgg attcaaccat
     2581 gcggtacgtg aaatcgcaac aggacgagta gacttcacca gccagaacca tggttatgca
     2641 gtcagccgcg aggatttgcc agagcacttg attattacac acgaagaaat caatgacaag
     2701 tcagtggaag gtgtgcgcca cagataccaa cctgctttct ctgttcaata ccacccagat
     2761 gcagctcctg ggccacacga cgctagctac ctatttgacg agtttatcga gatgatggaa
     2821 gtttttaaac aatcaaacta agaacgagta aaagctcgtc ggagaattta tgtaactgaa
     2881 cacggacgga aagctcagaa tttagagaaa ccaacttgga ttgtcaatcc ttccttgatt
     2941 ttctaaaatt caatcgcttt ctattcgtcc tttgtatctt atttaatgtc gccctgagag
     3001 gcgacgaata gaaaggagaa gggtgctccg tatttgctga actgaatacg ggctacggac
     3061 ggtgctaaaa agatagttat tcctagaact gacagttctt cgtcataact cctattttag
     3121 ctttgtccgc ttgacgccct taatatctta tatatgccta aacgtactga tattcaaaaa
     3181 attatggtga ttggttctgg tccgattatt attggtcagg ctgctgagtt tgactacgct
     3241 gggactcagg cttgcttgtc gttgaaagag gaaggttatg aggttgtttt ggttaactca
     3301 aatcctgcaa ccatcatgac ggacaaggaa attgctgaca aggtttacat tgaaccgatt
     3361 acacttgagt ttgtgacacg tattcttcgt aaggaacgtc cagatgcctt gctaccaaca
     3421 ctcggtggtc agacaggtct caacatggcc atagaattgt ctaaaaatgg tatcttagat
     3481 gagcttggcg ttgaacttct gggtaccaaa ttatctgcca ttgaccaagc ggaggaccgt
     3541 gacctcttta aacaattgat ggaagagctt gaacaaccca ttccagaatc tgaaattgtt
     3601 aacacagtag aagaagcagt tgcctttgca gcgacaattg gctacccagt catcgttcgt
     3661 ccagccttta ccctcggtgg tactggtggt ggtatgtgtg ccaatgagaa agaattgcgt
     3721 gaaatcactg aaaatggttt gaaattgtca cctgttaccc aatgtttgat tgagcgttcg
     3781 attgccggtt tcaaggaaat tgaatacgaa gtgatgcgtg actcagctga caatgccttg
     3841 gttgtttgta acatggaaaa ctttgaccca gttgggattc acacagggga ttccattgta
     3901 tttgcccctg cgcaaaccat gtcagactat gaaaaccaaa tgcttcgtga tgcgagcttg
     3961 agcattattc gtgccctcaa gattgaaggt ggatgtaatg ttcagctagc tcttgatcct
     4021 aacagcttca agtattatgt tatcgaagta aaccctcgtg tatcacgttc gtcagccctt
     4081 gcttctaaag cgactggata tccgattgct aagttggctg ccaagattgc agtaggtttg
     4141 accttggatg aggttataaa cccagttaca ggttcaacct atgccatgtt tgaaccagcc
     4201 cttgactacg tagttgctaa gattccacgt ttcccatttg acaagtttga aaagggtgaa
     4261 cgccgtctcg gtacacaaat gaaggcgact ggagaagtca tggcaatcgg tcgtaatatc
     4321 gaggaatctc ttctcaaggc ctgccgctcc cttgaaactg gggtgcacca caatgaaata
     4381 cctgaacttg cagcagtttc tgatgatgcc ttgattgaaa aggttgtcaa agcccaagat
     4441 gaccgtctct tctacgtatc agaagcaatt cgtcgtggct acacacctga agaaattgca
     4501 gagctaacaa aaattgatat cttctatctt gataaactct tgcatatctt tgaaattgag
     4561 caagaattgg gtgctcatcc acaagatcta gaagttttga aaacagccaa acttaatggt
     4621 ttctcagacc gtaagattgc tgaactctgg ggaacgactg atgatcaagt tcgccaactt
     4681 cgcttggaaa acaagattgt tccagtttat aagatggtag atacttgtgc ggcagagttc
     4741 gactctgaaa cgccatattt ctattcaacc tatggtttgg aaaatgaatc tatcaaatct
     4801 gataaagaat ctgtacttgt cctaggttca ggtccaatcc gtatcggtca aggggttgag
     4861 tttgactacg caaccgttca ctctgttaag gctatccagg cagctggtta tgaagctatc
     4921 atcatgaact caaacccaga gaccgtttca acagacttct ctgtatcaga taagctttac
     4981 tttgagccat tgacattcga agatgttatg aacgtcattg acttggaaca accaaaggga
     5041 gttatcgttc agtttggtgg tcaaacagcc atcaaccttg cggagccatt ggcaaaagca
     5101 ggtgtgacca tccttggtac acaggttgct gacctagacc gtgccgaaga ccgtgacctc
     5161 ttcgagcaag ctctcaaaga attggatatt ccacagccac caggacaaac ggctaccaat
     5221 gaagaagaag cagctcttgc agctcgtaag attggcttcc cagttcttgt ccgcccatct
     5281 tatgtacttg gtggacgtgc catggaaatc gttgaaaacg aagaagacct tcgttcttac
     5341 atgcgaactg ctgttaaggc tagtccagat catccagttc ttgtcgactc ttatatcgtt
     5401 gggcaagagt gcgaagttga tgccatttca gatggtaaag atgtactcat tcctggtatc
     5461 atggagcata tcgaacgtgc tggtgtccac tcaggtgact caatggctgt ttacccacca
     5521 caaaccttgt cgcaaaaagt tcaggagacc atcgcagact acaccaaacg cttagcaatc
     5581 ggtcttcact gccttggaat gatgaacatc cagtttgtta tcaaggatga aaaagtctac
     5641 gttattgagg tcaatccacg tgccagccgt accgttccat ttctatctaa ggtaaccaat
     5701 attcctatgg ctcaagtagc gaccaagctc attcttggtc aaagtttatc agaacttggc
     5761 taccaaaatg gactttaccc tgaaagcacc cgtgttcata tcaaggcacc tgtcttctcc
     5821 tttactaaac tagctaaggt agacagcttg ctcggtcctg aaatgaagtc aacaggtgaa
     5881 gttatgggtt ctgatgctac tttggaaaaa gctctctata aagcctttga agcttcttat
     5941 ctacacttgc caacttttgg taatgtcgtc tttaccatcg ctgatgatgc caaagaagaa
     6001 gccttgaact tggctcgtcg tttccaaaac attggttatg gaatccttgc gacagaaggg
     6061 acagcagcct tctttgctag tcatggcttg caagcccaac ctgttggtaa gattggtgat
     6121 gacgataagg atatcccaag ttttgtacgc aaaggaagaa ttcaagctat cattaacaca
     6181 gtaggaacaa aacgaactgc tgacgaagat ggtgagcaaa ttcgtcgttc agccattgaa
     6241 cacggggtgc ccctcttcac agcgctagat acagctaatg ccatgcttaa ggtacttgaa
     6301 agtcgtagct ttgttacaga agcgatttaa atagaaaaat aagatatagc agactgaatt
     6361 tagaacagta cacagggata ctaaaatatt tctagaaatt aatttgaatt ttctaattga
     6421 ttcgttcgca tcttatttca atctactata gaaaaaagtc tttaaaatta taaaacgcat
     6481 catatcaagg tttttcaaaa accctgatat gatgcgtttt attgtgggaa tatgtatttc
     6541 attttctact aaaattatgt ttttgaataa cctctatctt agtagtttgt ataatccccc
     6601 tcaatcagtt tttgcgataa gctttaatgc tatgactata ccactcttgc atttcttttg
     6661 atggtggtgt catataatcg ccatacatct gggttaaaaa ttggtcatat tttttgggaa
     6721 caggcaacat acggccctca aactcagtta aaatcagttc tttaaaggta tcaactggga
     6781 agatttcttt catcccttcc ttaccgatcc caactcctcc ttcatattga ggagtgttgg
     6841 ttacagcatt tttgactagt tgatcaattt tcttgtaaaa gtagcgagga ttgacaaatc
     6901 ggagagcgta ccaactacat aatctaagaa aatcttttag tttgctatca ccgtgaactg
     6961 ctcgtgattt tttgatataa gctagttgac gaagggccac atacttatag ctcttgtcga
     7021 caatgctcaa gtctgtaaat cgatcaattg ggaagacatc gatgaaaagg ctggtatcat
     7081 gacgcttgta cttaacatgg tcttctataa cagtagaagt gtccaaaatc gatgcgaaat
     7141 tatggaagta ccaagaagat gtatcgtagg aaagaacctt gtagcgaggg tgattttctt
     7201 cttcaataat cttcagtaaa cgctcataat cctcacgata aagggaaata tcaatatcat
     7261 catcccaagg aatcatacct ttgtggcgga tggctccaag catggttcca taactgagaa
     7321 aataaggaat atcatgtttc ttacaagtct catcaatata gtccagcagg gctagttgaa
     7381 tttctttaat ttcttttttt tctaaatatt gcatcctaat cctccaattt ataagcgtga
     7441 aattcatgac tgtagaagcg tttttcttct ggtggtaggg tcatataatc tccataaaat
     7501 tgtgtcaaaa tagtatcaaa tttttcaggt gcaggaaggc ttaaattctc aaagggtaaa
     7561 tcgattgttt tatcaaaggt accacttggg aagacttcct tttccttaaa ttttgaaggg
     7621 ataaaagcca tatactgccc attttcatga ctatattttt gaatttcttt ctcgatttta
     7681 tttgcaaaat aacgaggaga aaccggtcga aggagcaacc aaaaggctgt tcgtatccaa
     7741 tcttttaaaa ggctatcctt atagacaata tttttatgtt tactgaaaga cagcagtttg
     7801 aagctttcca gtttataaca agtatcaatg accttaggat catcaaagcg atctataggg
     7861 aaaatatcga taaagatacc agactcatag gtttttgtat ttcgagtatc aataatttta
     7921 gtcgtactgt cggttatctt gataaagttg ttaaagtagt tcttatcagt ttctaaggat
     7981 aggagcttat acttgctttt ttccttttga aaaatgttaa taaatcgttg gtagtcttct
     8041 ctaggcatgg ataaatcaat atcgtcgtcc caagggataa agccctcatg tcgaaccgcc
     8101 ccaatcagag taccgtagtt aataatatag ttgatattgt gctttttaca gagagtatca
     8161 atataatcca aaatttctaa ttcaatttgt ttggcatctt caacggttag ttgtttcatt
     8221 ttaaactcct atgatttttt aaatttattt tttaaggcta ggacatggtt taaaaattca
     8281 tagaaaatgc tatcttttgt gaagacaagt agactaatat aagagatagc tgatagcaag
     8341 acaatcaaac cagtattaat taaaaatggc aaattaatga ccatatccac aggatacacg
     8401 aaattaatca ggaaataaat tgctacaaag gaaagtgaaa agagagagta tcgaacagta
     8461 tagctaaaga tatgtcccaa gtggatgagt tgttttctat ggatgaaaat aatatagaaa
     8521 acaagtagag aagtctctga taacatagtt gtcagtaagt agtattcagg aagcacgata
     8581 tggttgaaaa agaggagact attcaagccc aaattgagta gcccagcaaa gactgtatag
     8641 actgtgatac gtttttcata gccattggta aagagaattt gggaaccaag aatggtatct
     8701 aaggccagga taatcgtacg aaaagcgaag agagaggtca agatgccgcc tccgatatat
     8761 ttttcactac cgtaaagtag gatggcattt ggtcctaaaa ccatgagtcc aaaactcagt
     8821 ggaatgataa agaagttaaa gattcgacta cctctattaa ccagagaaac ataggcttct
     8881 ttgtctcctt tccccagata gtaactgaga cgaggcacac tcactccaat tgcacctgtt
     8941 acaaccccag ctataacggt cacaattcgc tgagctatgg tatagtaact aacgttgaca
     9001 tcaatccctg ttttaacgag gaagaggcga tctaaaaaag tgaagagcat attggcattg
     9061 gcaaagacta acatggctgt cagagggaga aagagtggtt taaaatcact taggtgaatc
     9121 ttaacaagtt tgatgtctct tttaatccaa aaataactaa tcaggtagtt aatcagcgtc
     9181 gataaactca tcacaagtgt atagacaaca atatcgtgtt catttttaac aaataagaaa
     9241 atagagacca gcatcaggat acggatgaag gcagttttgt aaaagagaaa actgtaattt
     9301 tccagagctt cattgaccca ttcgattgaa aaaatctggg caatgagttg aatccccata
     9361 acaaggtaga cctttttgac gattggatta tcagtaaaga agagaggata ggctaggata
     9421 tagacagcag tggtcaaaat cgtacaagcg atgcacaaat aaaaaagact agaaaaggct
     9481 ctgttaagat cttttttgtt atccttgaca ttactgatag cccttaaacc gtagttatag
     9541 acaccataag ttgcaaaggg caagaaaaat gacaaaatag tgtcgactga gttgaagtaa
     9601 ccatagtcag ttcggtccaa gacacgcgcg acataggttc cagttaggat gggaaaaata
     9661 atattcaaga cacgaattcc catgtaagat agagcattta attttatact tttcattcaa
     9721 tttacctcgt ttttcattat atcataaagt tagctaataa gaaatgaagg gcagtaagtc
     9781 aagtaatcac tttgaagttt caaatcttaa attttaagtt ttctttaagg aaagtatatt
     9841 attctgaagg actctaaaat ttcgcaacca tttattagta attgctacag aattcctagt
     9901 cattactaga aatggactag tttctttgaa taatagaact gcataattct cctattctag
     9961 aaggggagga ccagtatttc ttttatgata ggactagatt gtggtataat agagagaata
    10021 agttttttta gtaagacaaa ggagaaaata gatgatttat gcaggaattc ttgctggtgg
    10081 aactggcaca cgcatgggaa tcagtaactt gccaaaacaa tttttagagc taggtgatcg
    10141 acctattttg attcatacaa ttgaaaaatt tgtcttggag ccaagtattg aaaaaattgt
    10201 agttggtgtt catggagact gggtttctca tgcagaagat cttgtagata aatatcttcc
    10261 tctttataag gaacgtatca tcattacaaa gggtggtgct gaccgcaata caagtattaa
    10321 gaaaattatt gaagcgattg atgcttatcg tccgcttact ccagaggata tcgttgttac
    10381 ccacgattct gttcgtccat ttattacact tcgcatgatt caggacaata tccaacttgc
    10441 ccaaaatcat gacgcagtgg acacagtggt agaagcggtt gatactatcg ttgaaagtac
    10501 caatggtcaa tttattacag atattccaaa tcgtgctcac ctttatcaag gacaaacacc
    10561 tcaaacattc cgttgcaagg acttcatgga cctttatgga tctctttctg atgaagagaa
    10621 ggaaatcttg acagatgcat gtaaaatctt tgtgatcaaa ggaaaagatg tggccttggc
    10681 caaaggcgaa tactcaaatc tgaagattac aaccgtaaca gatttgaaga ttgcaaaaag
    10741 tatgattgag aaagactagt aaaatgatta atcaaattta tcaactaact aagcctaagt
    10801 ttatcaatgt caaatatcag gaagaggcta ttgaccaaga gaatcatatc cttatccgtc
    10861 ccaactacat ggctgtctgt catgcggatc agcgttacta tcagggaaaa cgtgatccca
    10921 agattttgaa taaaaagctt ccaatggcga tgattcacga gtcatgtgga accgtcattt
    10981 ctgacccgac cggaacctac gaggttggtc aaaaagttgt catgattccc aatcagtctc
    11041 ctatgcagag tgatgaagaa ttctatgaaa actacatgac agggacccat ttcttgtcta
    11101 gtggatttga tggctttatg agagagtttg tttctctccc taaagatcgt gtggtggctt
    11161 atgatgctat tgaagatacg gttgcagcca ttacagagtt tgtcagtgtg ggcatgcacg
    11221 ctatgaatcg tctattgact cttgctcata gcaagcggga gcggatcgcc gttattggag
    11281 atggaagttt agcttttgtg gttgccaata ttatcaacta tactttgcca gaagcagaga
    11341 ttgtggttat tggtcgtcat tgggaaaagt tggaactctt ctcatttgcc aaagaatgct
    11401 atattacgga taatattcct gaagatttgg cctttgacca tgcttttgaa tgttgtggtg
    11461 gtgatggtac tggaccagct attaatgact tgattcgcta cattcgtcct cagggaacga
    11521 ttctcatgat gggagttagc gaatataaag tcaatctcaa tactcgcgat gccttagaaa
    11581 agggcttgat tttggttggg tcatctcgtt ctggtcgcat tgattttgaa aatgctatcc
    11641 aaatgatgga agtcaagaaa tttgccaatc gtcttaaaaa tatcctttat ctagaagaac
    11701 ctgtaagaga aattaaagat attcatcgtg tctttgcaac cgatttaaac acagccttta
    11761 aaacagtgtt taagtgggaa gtataagtac tggaggttaa ttgtggagaa aatcattaaa
    11821 gaaaaaattt cttccttact tagtcaagaa gaggaagtcc tcagtgttga acaactgggt
    11881 ggaatgacca atcaaaacta tttggccaaa acaacaaata agcaatacat tgttaaattc
    11941 tttggtaaag ggacagaaaa gcttatcaat cgacaagatg aaaagtacaa tcttgaacta
    12001 ctaaaggatt taggcttaga tgtaaaaaat tatctttttg atattgaagc tggtatcaaa
    12061 gtaaatgagt atatcgaatc tgcgattacg cttgattcaa cgtcaatcaa gaccaagttc
    12121 gacaaaattg ctccaatatt acaaactatt catacatctg ctaaggaatt aagaggagaa
    12181 tttgctcctt ttgaagaaat caaaaaatac gaatccttga ttgaagaaca aattccttat
    12241 gccaactatg aatctgttag aaatgcagtc ttctccttag agaaaagact ggctgactta
    12301 ggtgttgaca gaaaatcttg tcatatcgat ttggtgcctg aaaactttat cgaatcacct
    12361 caaggacgac tttatttgat tgactgggaa tattcatcaa tgaatgatcc aatgtgggat
    12421 ttggctgccc tctttttaga gtctgaattc acttcccaag aggaagaaac tttcttatct
    12481 cactatgaga gtgaccaaac accggtttct catgaaaaga ttgctattta taaaatttta
    12541 caagatacta tttggagtct atggactgta tataaggaag agcaaggtgc agattttggt
    12601 tactatggtg tgaatcgtta ccaaagagct gttaaaggtt tggcttctta tggaggttca
    12661 gatgaaaagt aaaaacggag ttccttttgg ccttctctca ggtattttct ggggcttggg
    12721 tctaacggtt agtgcttata tcttttcgat ttttacagat ttgtcaccct ttgtggtggc
    12781 tgcaactcat gattttttga gcatctttat cttactagct tttctcttgg taaaagaagg
    12841 gaaagttcgc gtctcaattt tcttaaatat tcgcaatgtc agtgttatca tcggagcctt
    12901 gctagcaggc cctatcggta tgcaggccaa tctttatgca gttaagtata tcggaagttc
    12961 tttagcttca tctgtatcgg ctatttaccc cgcgatttca gttctattgg ctttcttctt
    13021 tttgaagcac aagatttcga aaaatactgt atttgggatt gtcttgatta ttggagggat
    13081 tattgcccag acctataagg ttgaacaggt taattctttc tacattggga ttctttgtgc
    13141 tttggtttgt gctattgcat ggggaagtga gagtgttctt agctcttttg ccatggaaag
    13201 tgaattgagt gaaatcgaag ccctcttaat ccgtcaagta acttcgttct tgtcctatct
    13261 tgtgattgtg ctcttctctc atcagtcatt tgttgcagta gccaatggac aattgctagg
    13321 tctcatgatt gtctttgtag cctttgatat gatttcctat ttggcttatt atatcgctat
    13381 caatcgcttg caaccagcca aggctacagg cttgaacgtg agctatgtag tatggactgt
    13441 cttgttcgca gctcttttct tgggaacatc attagatatg ctgaccatta tgacgtcact
    13501 tgtcgtcatt gctggagttt atattattat taaagaataa aggagattcg tgtgaaagcc
    13561 attatcttag cagcgggatt gggaactcgc ttgcgtccta tgactgaaaa tacccctaaa
    13621 gccttggttc aggttaatca aaaacctttg attgaatacc aaattgagtt tctcaaagaa
    13681 aaaggaatca atgacatcat catcattgtt ggttatctta aagaacaatt cgattactta
    13741 aaagaaaaat acggtgttcg cctcgttttc aatgataaat acgctgacta caataacttt
    13801 tactctctct atcttgtaaa agaagaattg gccaacagct atgttattga tgctgacaat
    13861 tatctcttta aaaatatgtt ccgcaatgat ttgacacgtt cgacttattt tagtgtttat
    13921 cgtgaagatt gtaccaacga atggttcttg gtctatggag atgactacaa ggttcaagac
    13981 attattgttg atagcaaggc aggtcgcatc cttagtggtg tatccttctg ggatgctcca
    14041 actgcagaaa agattgtcag ctttatcgac aaggcttatg taagtggtga atttgttgat
    14101 ctctactggg acaatatggt taaggataat atcaaagagc tagatgtcta tgttgaagaa
    14161 ttagaaggca atagcattta tgagatcgat agtgtccaag actatcgtaa attagaagaa
    14221 attcttaaaa acgaaaatta aagattccaa catctgacaa aatagtcgga tgtttttttg
    14281 attttttacg aacttttacg aatagataga tgagtagaaa aagaaatgga gttatttatg
    14341 aaaatcacaa actatgaaat ctataagtta aaaaaatcag gtttgaccaa tcaacagatt
    14401 ttgaaagtgc tagaatacgg tgaaaatgtt gatcaggagc ttttgttggg tgatattgca
    14461 gatatctcag gttgccgaaa tccagctgtt tttatggagc gttattttca gatagacgat
    14521 gcgcatttgt cgaaagagtt tcaaaaattt ccatctttct ctattttaga tgactgttat
    14581 ccttgggatt tgagtgaaat atatgatgcg cctgtacttt tattttacaa gggaaatctt
    14641 gacctcctga aattcccgaa ggtagcggtc gtgggcagtc gtgcttgtag caaacaggga
    14701 gctaaatcag ttgaaaaagt cattcaaggc ttggaaaatg aactggttat tgtcagtggt
    14761 ctggccaagg gcattgacac agcagctcat atggcagctc ttcagaatgg cggaaaaacc
    14821 attgcagtga ttggaacagg actggatgtg ttttatccta aagccaataa acgcttgcaa
    14881 gactacatcg gcaatgacca tctggttcta agtgaatatg gacctggcga acaacctctg
    14941 aaatttcatt ttcctgcccg taatcgcatc attgctggac tttgtcgtgg tgtgattgta
    15001 gcagaggcta agatgcgttc aggtagtctc attacctgtg agcgagcaat ggaagaagga
    15061 cgcgatgttt ttgctattcc tggtagcatt ttagatggac tatcagacgg ttgccatcat
    15121 ttgattcaag aaggagcaaa attggtcacc agtgggcaag atgttcttgc ggaatttgaa
    15181 ttttaaaaat gacctaagct agaattctaa gaaaaaatca attttaagag aaaatgaacc
    15241 caacatttcc ataataaaac gcatattagc aagtttttaa cacttgataa tatgcgtttt
    15301 ttctaagtgg attagtagag tagaggattt ttctcatata atactcttcg aaaatctctt
    15361 caaactacgt cagcttccat ctgtaacctc aaaacagtat tttgagctga cttcgtcagt
    15421 cttatctaca acctcaaagc agtgctttga gcaacctgtg gctagcttcc tagtttgcgc
    15481 tttgattttc attgagtata agggaaagta tagtgaattg aaataagatg tgaacaactc
    15541 tatcaggaaa gtcaaattaa tttatagaaa tattttagca gccaaggtgc actgttatag
    15601 attcaataca ctataattta gtgtaattga gaaaggagaa atgattgtga ttgatgttgg
    15661 ctaggttatg ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa aaataaattc
    15721 ttcaaaagta gagattacaa ggcttgttta agaaagaatt caaagacctt gacaaataaa
    15781 aataaaatgg ttattataaa aaatggtctg aaatagatga tgatactttt cgaaaatctt
    15841 tttacgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta gcttccgagt
    15901 ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat ctgagtcagg
    15961 atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta ctaaagtatt
    16021 gagtttgtta ggattttagc gactagttgg ctgggaaagg aagatatttg tgacaaataa
    16081 taaactgtat tcgttgatag aatttagaaa taaaatatat gaagaattag aactttccag
    16141 aagtgattta gcgattttac tatgtgccat gcttatcgcc tctatcggat taaatatgga
    16201 ttcgactccc gtgattattg gagccatgtt aatctctcct ttgatgacac ctattctggg
    16261 aatggggctc tctctagcta tatttgattt taaattgtta agaaaatctt ttaaaatatt
    16321 agctattcaa attcttgcca gtctaatagc ttcaacactt tatttttatc tttctcccat
    16381 ttcgtatgct agttcggaga ttgttgctag aacctctccg actatttggg atgttctcat
    16441 tgcttttgta ggagggatag caggtattat tggtgctagg aaaaaagaga ccaataatat
    16501 tgttcctggt gttgctattg caaccgcctt gatgcctcct ctttgtacag taggttatgc
    16561 tattgcttct gctaatctaa aatttatcat aggctcctct tacctattcc tcatcaattg
    16621 tagctttatt gtcattgcga cttatatagg tgttaggttg atgatggtta agaaacatta
    16681 ttttaaagat aatgaagaag actctaaaat gcgtaggatt ttgcttctag ttgctgtttt
    16741 gctgatgatt ccgagtttca tctctgcaac gactttagtg agagaaacgt tgaaaaaaga
    16801 gtcccttaag aaatttatat cagagcagtt tcaggggtat aatattttga aaaaaaccta
    16861 ttctaaaaag actcataccc taaagctaac catttcagga aattatttga cagaagaaga
    16921 actcgatatg atttcaagta agagaggtga ctatggttta agtgatgttt ctgttcaagt
    16981 ttcacaattg tctgattcag aacaacttag taaggaagag ctggtggagt atttcttcca
    17041 gtatatcaag gataaggaag caaaagaaaa ggagaaagcc aataaatttg atacagagtc
    17101 tgaggagcaa taatttcttg agaatagctg gtttctctcg tgagtcttct atgtatatca
    17161 aaggaagact gaggttttaa gtataaaact tttcttctat tatagtagct aagtcttgac
    17221 agggttcaaa aaatggttta cactttataa agtttattac tttgaaaagg tgtgatactg
    17281 tggctacggc aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc atcgtggagt
    17341 cgcctgctaa ggccaagacg attgaaaaat atctaggcag aaactacaag gttttagcca
    17401 gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt gaaaataatt
    17461 atgaaccgca atatattaat atccgaggaa aaggccctct tatcaatgac ttgaaaaaag
    17521 aagctaaaaa agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa ggagaagcga
    17581 tttcttggca tttggcccat attctcaact tggatgaaaa tgatgccaac cgtgtggtct
    17641 tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa agaacctcgt aagatcgata
    17701 tggacttggt cgatgcccaa caagctcgtc ggatcttgga tcgcttggta gggtattcga
    17761 tttcgcctat tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc gttcagtcca
    17821 ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa tgccttccag ccagaagaat
    17881 actggacagt tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct tccttctatg
    17941 gagtagatgg taaaaagatg aaactgacca gcaatgacga agtcaaggaa gtcttgtctc
    18001 gtctgactag taaagacttt tcagtagatc aggtggataa gaaagagcgc aagcgcaatg
    18061 ctcctttacc ctataccact tcatctatgc agatggatgc tgccaataaa atcaatttcc
    18121 gtactcgaaa aaccatgatg gttgcccaac agctctatga aggaattaat atcggttctg
    18181 gtgttcaagg tttgattacc tatatgcgta ccgattcgac tcgtatcagt cctgtagcgc
    18241 aaaatgaggc ggcaagcttc attacggatc gttttggtag taagtattct aagcacggta
    18301 gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga ggctattcgt ccgtcaagtg
    18361 tctttaatac accagaaagc atcgctaagt atctggacaa ggatcagctc aagctatata
    18421 cccttatctg gaatcgtttt gtggctagcc agatgacagc ggccgttttt gataccatgg
    18481 ctgttaaatt gtctcaaaaa ggggttcaat ttgctgccaa tggtagtcag gttaagtttg
    18541 atggttatct tgccatttat aatgattctg acaagaataa gatgttaccg gacatggttg
    18601 ttggagatgt ggtcaaacag gtcaatagca aaccagagca acatttcacc caaccgcctg
    18661 cccgttattc tgaagcaaca ctgattaaaa ccttagagga aaatggggtt ggacgtccat
    18721 caacctacgc gccaaccatt gaaaccattc agaaacgtta ttatgttcgc ctggcagcca
    18781 aacgttttga accgacagag ttgggagaaa ttgtcaataa gctcatcgtt gaatatttcc
    18841 cagatatcgt aaacgtgacc ttcacagctg aaatggaagg taaactggat gatgtcgaag
    18901 ttggaaaaga gcagtggcga cgggtcattg atgcctttta caaaccattc tctaaagaag
    18961 ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa ggatgaacca gctggatttg
    19021 actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt aaattctacg
    19081 cttgtagcaa tttcccagat tgccgtcata cccaagcaat cgtgaaagag attggtgttg
    19141 agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt aatcgcctat
    19201 tctatggttg caatcgctat ccagaatgtg aatttacctc ttgggacaag cctgttggtc
    19261 gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa agtccgtggt ggtggcaagc
    19321 aggttgtttg tagcaaaggc gattacgagg aagaaaagat taaataagag gaggggcccg
    19381 aaagtaaatt tcaggctcct tttggttaga acttgacaaa atacatcatt ttatgcgaaa
    19441 ctagaagaag attattttaa ctaggagaag ttatgcgtct tatctatctg ataattggtt
    19501 ttttatcact ggccttggct attgttgggg ttgttttacc cttgttgccg acaacgcctt
    19561 tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgtttcgaa gactggcttt
    19621 atcataccaa gctctatcaa acatatgtag ctgattttcg cgagaccaag tctattacgc
    19681 gtgaacgaaa gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt tctatttatt
    19741 ttgcacctct tttaccagtc aaaatcggtt tgggtgcttt gaccatcttt atcacttatt
    19801 atctcttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt accttgataa
    19861 aattgaaagc atattcataa caatatgata taataaattt gaagtaatat tcaaggagaa
    19921 tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag cgatgcaggc
    19981 tggagctcgt cggattgaac tctgtgataa tctagcagtt ggtgggacaa cacctagcta
    20041 tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca tcatgaccat
    20101 gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta tcatgctaga
    20161 agacatttgt ttgactgctc aggctggaag tcaaggggtt gtatttggag ctttaactgc
    20221 tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa aaggaatgga
    20281 aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg aagctattga
    20341 ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt ctggcgactc
    20401 cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag gtaaaattga
    20461 aattctacca ggtgggggga ttgaccttga caaccgtcaa acctttattg accaggtggg
    20521 ggtaacacaa ttgcatggta ctaaggttgt tttttaaaaa atagaaagga actgctagcc
    20581 ttgggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt aatcaagaaa
    20641 aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt tgccagattt
    20701 tgcaaggtga ctttgtcatg actgtgtcca tcactgctga taatgtgaac tttcaagtct
    20761 ttgaccaaga gactggtgac ctctatcctc acgttcatat ggaaagcatg aggggaagtt
    20821 ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg aaggcttgtt
    20881 ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa gttcaggaaa
    20941 agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct gtattgcgcc
    21001 atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat aagctggaaa
    21061 agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta gctaatttgc
    21121 tttcacaaaa ggggatttat ccagccttcc atatgagcaa gcgctactgg attagtgtgt
    21181 cccttgatga tactttatca gatgaagaag tactggaatt gatagaaaaa agttggaact
    21241 taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaatta gctaaatatt
    21301 ctttactgaa gaaattttta gaaaatatag gatttaccac actagaggaa tatggtgcca
    21361 tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctgc tcgcctcact
    21421 gtcatgatga cctcggaatg gcagtggcaa atagccttgc tgctgtcaag aatggtgcag
    21481 gacgtgttga agggactatc aatggtatta gggagcgagc tgaaaatgct gctttggaag
    21541 aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc agtattgtcc
    21601 taaatgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt ccagttccta
    21661 aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt caccaagatg
    21721 gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt ggtgttaaga
    21781 ttccgcttgg agaattatct ggtcgccatg cttttgttga gaaactgaga gaattggccc
    21841 tagattttac agaagaggat atcaaaccac tctttgctaa gttcaaggca ctggccgata
    21901 agaagtaaga aatcacagat gcagatactc gagctttggt agctggaacc atggttgaaa
    21961 atccagaagg cttccacttt gatgatttac aacttcaaac tcatgcagat aatgacattg
    22021 aagcgctcgt tagcctagcc aatatggatg gtgagaaagt cgaatttaat gcgacagggc
    22081 aaggttccgt tgaagcaatc tttaacgcta tcgataagtt ctttaaccaa tctgttcgtt
    22141 tggtgtccta cactatcaat gcggtaacag atggaatcga tgcccaggat cgggttttgg
    22201 tcactgttga aaacagagat acagaaacca tctttaatgc agcagggctt gattttgatg
    22261 tgttgaaggc ttctgctatt gcctatataa acgctaatac ctttgttcaa aaagagaatg
    22321 caggtgagat gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa aggagaaggc
    22381 tatggcaaag aaaatagtag ctctagtagg agacggaatt ggcccagaaa tcatggaggc
    22441 tggtttagaa gttctggagg ctctagctga aaaaacaggt tttgactatg agattgacag
    22501 acgaccgttc ggaggtgcag atattgatgc agcaggacct cccttacctg atgaaaccct
    22561 taaggcaagt agggaagcag atgctatcct actagtagct atcggtagtc ctcagtatga
    22621 tggagtagcg gttcgccctg aacaaggcct gatggctctc cgtaaggaac tcaatcttta
    22681 cgctaatatt cgtcctgtaa aaatctttga cagtctcaag tatttgtcac cactcaaacc
    22741 ggaacgaatt tctggtgtag actttgtcgt ggtgcgtgaa ttgacaggcg agatttactt
    22801 tggagatcat attcttgaag agcgcaaagc gcgtgatatc aacgactata gctatgagga
    22861 agtggagcgg attattcgca aagcctttga aattgcaaga aatcgcagaa aaatcgttac
    22921 tagtatcgat aagcaaaatg ttctagcgac ctcaaaactc tggcggaaag tagctgagga
    22981 agtcgcacag gatttcccag atgtaacctt ggaacaccag ctggtagact cagctgctat
    23041 gcttatgatt accaatcctg ctaagtttga tgttattgta acggagaatc tttttggaga
    23101 tattttatct gatgaatcaa gcgtcttatc tggtacactt ggggttatgc catcagccag
    23161 tcattctgaa aatggaccaa gtctctatga acctattcac ggttcagcac ctgatattgc
    23221 aggtcaagga attgccaatc ctatttccat gattttatca gttgtcatga tgttgagaga
    23281 tagtttcgga cgttatgagg atacagagcg tatcaaacgt gctgttgaga caagtctggc
    23341 ggcaggaatt ttaacgagag atataggagg tcaggcttca acaaaggaaa tgatggaagc
    23401 tattattgca aggttatgaa gttagacgaa aaaattactc tagtcctttt gatttggaat
    23461 gtcatcattt tcttgattta tggcattgac aaattcaagg caagaagaag agcttggcgc
    23521 atcccagaga aaatcttact cattttagcc cttacttgtg gtggttttgg ggcctggtta
    23581 gctggaatca cttttcacca caagactcga aaatggtact ttaaaacagt ttggtttctt
    23641 gggatggtga ccacactagt agccttatat tttatttgga ggtaatggat ggcagggtct
    23701 tcgagggaat acgctgcttg ggctctagcg gactatggtt ttaaggtcgt gattgcagga
    23761 tctttcggtg acattcatta caataatgaa ctcaataatg gcatgttgcc aatcgttcag
    23821 cctagagagg ttagagagaa actagcccag ctaaaaccaa ccgaccaggt aactgtggac
    23881 ttggaacaac aaaaaatcat ctcaccagtt gaagaattca ccttcgagat agatagcgag
    23941 tggaaacata aactcctaaa tagtttggat gatatcggta ttaccttgca gtatgaagag
    24001 ttgattgctg cttatgaaaa acaacgacca gcctactggc aggattagaa aaaatagaaa
    24061 aggaaatata gtaaactgaa ataagatgta aacaaatgaa ttggagctta acatccattt
    24121 ccagcaattt tttagaaact acagtggact attctggatt caacacatta taaaattatg
    24181 acaaaacaca ttcacaagaa ggctacgaca ttttaaaagg tgagggcgga tgtatcgttt
    24241 gccctactaa agttggttac attatcatga ccagtgacaa ggcaggactt gagcgtaagt
    24301 tcgcagccaa agaacgtaag cgtaacaaac caggtgttgt tctctgcggt agcatggatg
    24361 aacttcgcgc tttagcgcaa ctcaacccag aaattgaagc attctactaa aaacattggg
    24421 atgaagatat tcttcttggt tgtatccttc cttggaaacc agaagcctct gaaaaactca
    24481 aagcatacgg ggatggccgt gaagaactta tgactgatgt acgtggtact agctgttttg
    24541 ttatcaagtt tggaaaagca ggtgaacaat tggctgccaa gctttgggaa gaaggtaaaa
    24601 tggtctacgc ctcatctgct tcaatgacaa aacgattgaa actcgctatg agagcaaggt
    24661 gtaatggtgt ctatggtcga taaggacggc aaactcatcc cagaacaagg aggagcacgt
    24721 tcaacttcac cagcaccagt tgtgatccgt aaagggcttg acattgatat agtaaaatga
    24781 agtaagagca ggacaaatta atcaggacag tcaaatcgat ttctaacaat gttttagaag
    24841 tagaggtgta ctattctagt ttcaatccac tataaaatca tgatgcacct gtcagatact
    24901 tttaactcat gggactaccg tcaggttgag tattattagg atagagaaga agtctagtgt
    24961 taaggacatt acagctcata atactaggct tttttataga aattcttttc tttttctata
    25021 ggatatggta ttctatgtag aaaatatatg ttaataagta atgccaatat ttaaacatca
    25081 ttagtaaaag gagttagatt gatgaataaa agaaaagtta gtttagaaga tttttataaa
    25141 tggtatagtc taaataaaga agagttatta aataaggcaa ctgttggtga aaagtttaat
    25201 gataaattaa aagaagagtt tctccaggaa tggcctttgg ataggatttt aacaatgtca
    25261 atcgatgaat atgtaatagg aaagggacag caaaataagt ctttatgcta cgctcttgag
    25321 aagggaaaat acaaaaatct atttcttgga atttctggtg gctcagcttc aaaatttggt
    25381 atttattgga ataaaaaaac aaacaaatat aaagatcaag ctaataatga gatttcagag
    25441 ttggatcagc gattttcaaa attaaaatca gatttgtatg aaattatcaa agaaggtatt
    25501 cgttttaact ttgaaaatcc tatttttgat atgaaaagat caacaaatga atttattggt
    25561 cgttctgcta tggtgacaaa attactttgt atctattctg ggggagatcc tttctttggt
    25621 gtaaatatta atagtcagaa agaattttgg aaccactttg tttctcagac aaatcaaggt
    25681 ggaccttatc tgcaaaatca taaaataatt gaactggtgt ccaaaactta tcctgagttg
    25741 gagccatcga aattaggaac tatgcttttt gagtattcta agctttttat ggaaaataag
    25801 gaagacaata gtacaatgga ttcatcaaac aattttcgtc atcaattaac tcaatctcta
    25861 ttaaagtctc caaaccttat ccttcgtggt gctcctggca caggaaagac ttatcttgct
    25921 aaagaaattg ccaaagaatt aacggatggc aacgaagacc aaatcggatt tgtacaattt
    25981 cacccatcct atgattatac ggattttgta gaaggtttaa gaccagtatc aaatggggat
    26041 ggagctattg agtttaggct acaggacggt atttttaaag atttttgtca gaaagcaaaa
    26101 gaaacccaat tgattggagg acaagataat tttgatgagg cttgggattc ttacttagaa
    26161 tatataaatg ttgctgaaga aaaagaatat ataacaaaaa catcttactt atctgttaat
    26221 agtagacaaa atttgtcagt aaattatgat agtggtgttc caggatggtc actacctagc
    26281 aaatatgttt acgagttgta taaagataaa aattataata agcaagaata ctacaaaagt
    26341 ggtggaaaaa ctgtcctaga aacattgaga aagagatttg gtttgaaaga ctatgtttcc
    26401 ccaacagaaa ttgatactga taagaaattc gtcttcatca tcgatgaaat caatcgtggg
    26461 gagatttcta agatttttgg cgaactcttt ttctctatcg accctggcta tcgtggtgaa
    26521 aaaggaagtg tttctaccca atatgcaaat ctacacgaaa ctgatgaaaa gttctatatc
    26581 cccgaaaatg tttacatcat cggaactatg aatgatattg atcgttcagt ggataccttt
    26641 gattttgcta tgcgtcgtcg ttttcgtttt gttgaagtta ctgccgaggg tcaagttggc
    26701 atgttggata aagagctgaa tatccatgca gaagaagcaa aaattcgtct aagaaacttg
    26761 aacgctgcta tcgaaaatgt tcaggaatta aacagtcatt atcatattgg accaagttat
    26821 tttcttaagt tgaaggatgt agattttgac tatgaattac tctggtctga ttatattaag
    26881 cctctcctag aagactactt gcgaggttct tatgatgagg ttgaaacttt ggaaactttg
    26941 aaaaaagcat ttgaactgac aaataatgat caaactggtc aacaagatac tggtgataat
    27001 gatgcggatt actgataatc aatacaagat tattaaagaa aaatttgttg aagaatatcc
    27061 taaactaagc aatcttcttt tagacagaac cttggaaagt ctatcccaag atgaacgtat
    27121 tttcattttt ccaaatgatt tgactcatac tcctgatttg gataaggacc aaaagatttt
    27181 tgaaacagtc aatcagaaaa tcaagacagg gaacgtgatt ggttttcttg gatatggtca
    27241 ggaaagatta acgatttcct cacgattttc tgatgagagt aatgaccatt ttttgcatta
    27301 tctcttaaac aagattcttc atatcaatct cactagttta gatgttgctt tgtctcgtga
    27361 agagaggctt tatcaacttt tggtgtatct ctttcccaag tatctacaag ctgctattcg
    27421 aaaaggtctt tataaggaat atcatcgatt ttctcataac gacagtcatg ttaagggagt
    27481 gattgatgta agaaaccatc tcaagaaaaa tcttcctttc acgggaaata ttgcctacgt
    27541 aacgagagag ttcacctatg ataatcccct catgcagttg gtccgttaca ctattgaata
    27601 cattaagaat cagaaaagca ttggtcaagg ggtactagat aatctctcaa ctagtcgtga
    27661 aaacgtatct gaaatcgtgc gtgtaacacc ctcttataaa ctagctgatc gtgctaagat
    27721 tattcgggga aatcaatcta aacctatacg tcatgcatac tttcacgagt acagaaactt
    27781 acaagaactt tgtctgatga tcctaaacca agaaaagcac ggtttagggt atcaagatca
    27841 aaaaatctat ggtattctct ttgatgttgc ctggctttgg gaagagtatg tttacacctt
    27901 gttgccaaaa ggttttgtac atcccagaaa taaggataag acggatggaa tttcagtatt
    27961 ttctgttggg aaacgaaaag tatatccaga tttttatgac agagaacgaa agattgttct
    28021 agatgcaaaa tataaaaaac tggaattgac tgaaaaagga atcaaccgtg aggacttatt
    28081 ccagctgatt tcctattctt atattttaaa agctgagaag gctggactga tttttcctag
    28141 tatggagcag tcagtaaata gtgaaatagg aaaagtagct ggctatggag ctcaattgaa
    28201 gaagtggtct attcgaatcc ctcagaatgc ctcattctat agtacatttt gtaaaatgat
    28261 ggaaaattca gaagaaaatt ttaaagcgat tattgatgaa gaagtgggga gaaaataatt
    28321 tcctctcttt cttttatttt taacacaagt aaaacccgaa caatatattt caattcataa
    28381 aataatttga caaaaactgt actttggttt ataataaatt aaggaaacgt cggaaaagac
    28441 gtagtgatgc gagagcatag gtaggtcatt acaaaagaaa cgagacatcg atatgttaaa
    28501 tgaatttcca atttttgatt acgaagatat tcaattgatt ccaaataaat gtgtcattaa
    28561 aagccgtgca gaagcggata caagtgtcac tttaggaaat cacaccttta aactacctgt
    28621 tgtgccagcg aatatgcaga cgattttgga tgaaaatgta gcagagcaac tggctaaagg
    28681 tggttacttc tacattatgc accgttttga tgaggcagga cgcattcctt ttattaaacg
    28741 aatgcacgat caagggctca ttgcttctat ctctgtcggt gttaaggact atgagtatga
    28801 tttcgttaga cagctcaaga ctgatgctcc tgagtatatc actattgata ttgctcatgg
    28861 tcatgcggat agcgtgattt ctatgattca acacatcaag aaagaattgc cagatacctt
    28921 tgtcattgct ggaaatgtgg gaacaccaga agctgtgcgt gaattggaaa atgctggtgc
    28981 ggatgctact aaggtcggaa tcggtcctgg taaggtttgt atcaccaagg ttaagactgg
    29041 ttttggtaca ggtggttggc agttggctgc tctacgctgg tgtgccaagg ctgcgcgtaa
    29101 accgattatc gctgatggag gaattcgtac tcacggtgat attgccaagt ctatccgctt
    29161 cggtgctagc atgatcatga ttggttccct ctttgcagga cacattgaaa gtccagggaa
    29221 aacgattgaa gtcgatggtg aacagttcaa agaatattat ggttcagcct cacaatatca
    29281 gaaaggtgct tacaaaaatg tggaaggcaa acgtatcttg cttcctgcta aaggtcatct
    29341 gcaagacact ttaactgaga tggaacaaga ccttcaaagt gctatttctt atgcaggtgg
    29401 acgtcaggtt gctgacctta aacacgttga ttatgtgatc gtgaaaaact ccatctggaa
    29461 tggggatgct tcccactaag acggggtctt tgactaaaaa acttgttatt agagcaaatt
    29521 tctgttataa taaaacaagt ttccaccctt agtgtaatgg atatcacgta agattccggt
    29581 tcttgagatg ggggttcgat tccctcaggg tggatgtaaa catcctaaaa agcctttaat
    29641 agggcttttt tctttacact gctctaaatt tgccgctaaa actgagaatc tctgtctaaa
    29701 gaattcccaa atgctttcca gtcccgtttt agagtgactc agggggcttt ttttgatata
    29761 ataaaaagga ctattatcag ttagaaagag gttggtatga aagaattaca aactgtacta
    29821 aagaaccatt ttgcaatcga atttacagac aaaaatttac tggaaactgc ctttactcat
    29881 acgagttatg ccaatgagca ccgcctctta aaaatttcac acaatgaacg cttggaattt
    29941 ttaggagacg ctgttctaca gttattgatt tcagaatatc tatataaaaa atatcctaaa
    30001 aagcctgaag gtgacctatc aaaactccgt gctatgattg tccgtgagga gagtttagct
    30061 ggttttgcgc gtgattgcca gtttgaccag tttatcaagt tgggtaaagg ggaagaaaaa
    30121 tctggtggtc gcaatcgtga caccattctt ggtgatgcct ttgaagcctt tcttggtgcc
    30181 cttcttttgg ataaggatgt ggccaaggtc aaggaattta tctatcaagt catgattcct
    30241 aaggttgaag caggcgagtt tgagatgatt acagactata aaacccatct ccaagagttg
    30301 cttcaggtca atggtgatgt ggctattcgt tatcaggtga tttctgaaac agggcctgct
    30361 cacgataagg tctttgatgt agaagttctt gttgaaggta agagcatcgg tcaaggccaa
    30421 ggtcgttcta agaaattagc agagcaggaa gctgccaaaa atgccgttga gaaggggctg
    30481 gattcatgta tttaaaggaa atcgaaattc aggggttcaa gtcttttgct gataagacca
    30541 aggtcgtttt tgaccaaggt gtgacggcag ttgttggacc caatggatct ggaaagtcca
    30601 atattacaga aagtctgcgt tgggctttgg gggagtctag tgtcaagagt ctccgtgggg
    30661 gcaagatgcc ggatgtcatc tttgctggaa ccgaaagtcg caaaccgctc aattatgctt
    30721 ctgtagttgt gactctggat aatcatgacg gatttatcaa ggatgcaggt caagaaatca
    30781 gggtggaacg ccatatctat cgtagtggag atagcgaata caagattgac ggcaagaaag
    30841 tccgtctgcg tgatattcat gacctcttct tggatactgg attgggacga gattccttct
    30901 ctatcatttc ccaagggaag gttgaggaga tttttaattc taagcctgag gaacgccgag
    30961 ctatttttga agaagctgca ggagttttaa aatacaagac tcgcagaaaa gaaactgaga
    31021 gtaaactgca acaaactcag gataatctag accgcttaga ggacattatc tacgagttgg
    31081 ataatcaaat caagcctctt gagaagcaag ctgagaatgc ccgtaagttt ttagacttgg
    31141 aaggacaacg taaggctatt tatttagacg ttctggttgc tcaaatcaag gaaaataagg
    31201 cagaactaga gtcgacagaa gaagagctgg ctcaggttca agaactcttg atgagttatt
    31261 accaaaagcg tgaaaaatta gaagaagaaa atcaaactct taaaaagcaa cgccaagatt
    31321 tacaggctga aatggccaaa gaccaaggca gtttgatgga cttgactagt ctgattagtg
    31381 atttagaaag aaaattagcc ctatcgaaac tggagtccga gcaagtagcc ctgaatcaac
    31441 aggaggcaca agctcgtttg gctactttgg aggataagag aaattcactc agcaaagaaa
    31501 agtatgataa agaaagctct ttagctctgt tagagggaaa tctagtccaa aataatcaaa
    31561 aactcaatcg tttagaagct gaattgctgg ctttctcaga cgatcctgat cagatgattg
    31621 agctcttacg tgaacgcttt gtagctcttt tacaagaaga agcggatgtc tcaaaccagt
    31681 tgacccgtat tgagaatgag ttggaaaata gtcgtcagct ttctcaaaaa caagcagatc
    31741 aactagaaaa gctgaaagag caattggcta tagctaaaga gaaggctagt cagcaaaagg
    31801 aagagcttga aactgccaag gagcaggttc agaaattatt ggctgactac caagctattg
    31861 ccaaggagca agaggagcag aaaacttcct atcaagctca acaaagccaa ctctttgacc
    31921 gtctggataa tctcaaaaac aagcaggcca gagctcaaag tttggaaaat atcctgagaa
    31981 atcatagtaa cttttatgca ggtgttaaga gtgttctcca agaaaaagat cgcctaggtg
    32041 ggattattgg tgcagtcagt gagcatctga cctttgatat gcattatcaa actgccctag
    32101 aaattgcgct tggagcgagt agccaacata tcatcgtaga agatgaagag tcggcaacca
    32161 aggctattga cttccttaaa cggaacagag ccggtcgtgc aacctttctt cctttgacca
    32221 ctatcaaggc gcgtacgatt tctagtcaga accaagatgc tatcgctgta agcccaggtt
    32281 tccttgggat ggcagatgag ttggtgactt ttgatactag actggaagcc attttcaaga
    32341 acttgctagc tacgacggct atctttgata ctgtagaaca tgcgcgtgca gcagcgcgcc
    32401 aggttcgtta tcaggttcgt atggtgacat tggacggaac agagctgcgc acaggtggtt
    32461 cttatgcagg tggagctaat cgccagaata acagtatttt catcaagcca gaactggagc
    32521 aattacaaaa agaaattgct gaagaagaag caagcttggg ttcagaagag gcgactttga
    32581 agaccttaca agaccagatg gctagattgt ccgaattatt agaagccatc aaatctcaag
    32641 gagaacaggc acgtattcag gagcaaggct tgtccctcgc ttatcagcaa actagtcagc
    32701 aagttgaaga actggaaact ctttggaaac tccaagaaga ggaattagat cgtctttctg
    32761 acggagattg gcaagcagat aaggaaaaat gccaagatcg tcttgctact atcgccagtg
    32821 acaagcaaaa tctggaagct gagattgaag agattaagtc taacaaaaat gccatccaag
    32881 aacgctatca aaacttgcag gaagagctag cgcaagctcg tttgcttaag acagaactgc
    32941 aagggcaaaa acgttatgaa gttgctgata ttgaacgctt aggcaaggaa ttggacaatc
    33001 ttaatatcga acaagaagaa attcagcgca tgctccaaga aaaagttgac aatcttgaga
    33061 aggttgatac agaattgctc agtcaacagg cggaagaatc caaaactcag aaaacaaatc
    33121 tccaacaagg tttgattcgc aagcagtttg agttggatga tatagaaggt caactggatg
    33181 atattgccag tcacttggat caagctcgcc agcagaatga ggagtggatt cgcaagcaaa
    33241 cacgtgctga agccaagaaa gaaaaggtca gcgagcgctt gcgccatcta caaaatcaat
    33301 taacagacca gtaccagatc agctacacag aagctttaga aaaggcacat gaattggaaa
    33361 acctcaatct ggcagagcaa gaggtgcagg atttagagaa ggctattcgc tcattgggac
    33421 ctgtcaactt ggaagctatt gaccagtacg aagaagttca caaccgtctg gactttctaa
    33481 atagtcagcg agatgatatt ttgtcagcga aaaatctgct ccttgaaacc attacagaga
    33541 tgaatgatga ggtcaaggaa cgctttaaat caacctttga agctattcgt gagtccttta
    33601 aagtgacctt caagcagatg tttggcggag gtcaggcaga cttgatattg actgagggcg
    33661 accttttaac agctggtgtg gagatttctg ttcaacctcc aggtaagaaa atccagtcgc
    33721 ttaacctcat gagtggtggt gaaaaagctc tatcggctct tgccttgctt ttctccatta
    33781 ttcgtgtcaa gaccattcct tttgtcatct tggatgaggt ggaagctgcg ctggatgaag
    33841 ccaatgttaa acgttttggg gattacctca accgctttga caaggacagc cagtttatcg
    33901 tcgtaaccca ccgtaaggga accatggcag cggctgattc catctatgga gtgaccatgc
    33961 aagaatcggg tgtttcaaag attgtttcag ttaagttaaa agatttagaa agtattgaag
    34021 gatgacaatt aaactagtag caacggatat ggacggaacc ttcctagatg ggaatggacg
    34081 ctttgatatg gatcgtctca agtctctctt ggcttcctac aaggaaaaag ggatttactt
    34141 tgcggtggct tcgggtcggg gatttctgtc tctggaaaaa ttatttgctg gtgttcgtga
    34201 tgacattatt ttcatcgcgg aaaatggcag tttggtagag tatcaaggtc aggacttgta
    34261 tgaagcgact atgtctcgtg acttttatct ggcaactttt gaaaagctga aaacgtcacc
    34321 ttatgtagat atcaataaac tgctcttgac gggtaagaag ggttcatatg ttctagatac
    34381 ggttgatgag acctatttga aagtgagtca gcattataat gaaaatatcc aaaaagtagc
    34441 gagtttggaa gatatcacag atgacatttt caaatttaca accaacttca cagaagaaac
    34501 gctagaagct ggtgaagctt gggttaatga acatgtccct ggtgttaagg ctatgacaac
    34561 tggctttgaa tctattgata ttgttctgga ctatgtcgat aagggtgtag ctattgttga
    34621 attagctaaa aaacttggta tcacaatgga tcaggtcatg gcttttggag acaatcttaa
    34681 tgacttacat atgatgcagg ttgtgggaca tcctgtagct cctgaaaatg cacgacctga
    34741 aattttagaa ttagcaaaga ctgtgattgg tcaccataag gaccagtcgg ttatagctta
    34801 tatggagggc ttataatggc agatataaaa ttaatcgcat tggacttgga cgggaccttg
    34861 ctgactactg ataaaaggct gacggatcgt accaaggaaa ccttgaaagc tgcgcgtgat
    34921 cgtggtatca aggtcgtatt gacaactggt cgtcccttaa aagctatgga tttctttctc
    34981 catgagctag ggactgacgg tcaggaagat gagtatacca ttacttttaa tggtggtttg
    35041 gttcagaaaa atacaggtga aatccttgat aagacagtct tttcatatga tgatgtggca
    35101 cgcttgtatg aagaaacaga gaaattatca ctgcctcttg acgctatctc agaaggaact
    35161 gtttatcaaa ttcaatcgga ccaagaaagt ctttatgcca aattcaatcc agctttgact
    35221 tttgttccag ttgattttga agacctgtct aatcaaatga cctacaacaa atgcgtgacc
    35281 gcctttgctc aagaaccctt ggatgcagcc attcagaaga tttctccaga attgtttgac
    35341 caatatgaaa tctttaaatc acgtgaaatg ttgctagaat ggtcaccaaa gaatgttcat
    35401 aaagcaacag gtttggcaaa actaattagc catcttggaa ttgatcaaag tcaagtgatg
    35461 gcctgtggtg acgaggccaa tgacctctct atgattgaat gggcagggct cggtgttgcc
    35521 atgcaaaacg ctgttcctga agtcaaggca gtcgcaaatg tggtaactcc tatgaccaat
    35581 gatgaagaag ctgtcgcctg ggctatcgaa gaatatgtgc taaaggagaa ctaagatatg
    35641 ggattgtttg accgtctatt cggaaaaaaa gaagaaccta aaatcgaaga agttgtaaaa
    35701 gaagctctgg aaaatcttga tttgtctgaa gatattgagc ctgccttcac agaagttgag
    35761 gaagtttctc aggaagaagc agaggttgaa attgttgaac aagctgtgtt ccaagaagag
    35821 gaaatccaag acacagttga agaaagtcag gattcagagc cagctgtagg ggtttctcaa
    35881 gaagaaatag aagaattacc aaactcagaa gaattaccag aggaagagaa gcttgagcac
    35941 gaaggaacta tagaagaaaa taattctgaa attcttgaag cagaaaggcc tcaaacagaa
    36001 gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa ctcgcacagg tttcggtgcc
    36061 cgcttgaatg ccttctttgc taacttccgc tctgttgacg aagaattttt cgaggaactg
    36121 gaagaactgc tgattatgag tgatgttggt gtccaagtcg cttctaactt aacggaggaa
    36181 ctacgttacg aagccaagct tgaaaatgcc aagaaacctg atgcacttcg tcgtgtcatc
    36241 attgagaaat tggttgagct ttatgaaaag gatggtagct acgatgaaag catccacttc
    36301 caagataact tgacagttat gctctttgtt ggtgtgaatg gtgttgggaa aacaacttct
    36361 atcggaaaac tagcccaccg ctacaaacaa gctggtaaga aggtcatgct ggttgcagca
    36421 gataccttcc gtgcgggtgc agtagctcag ctagctgaat ggggccgacg agtagatgtt
    36481 ccagtagtaa ctggacctga aaaagctgat ccagccagcg tggtctttga tggtatggaa
    36541 cgtgccgtgg ctgaaggtat cgatattctc atgattgata ctgctggtcg tctgcaaaat
    36601 aaggataacc ttatggctga gttggaaaag attggtcgta ttatcaaacg tgttgtgcca
    36661 gaagcaccac atgaaacctt cttggcactt gatgcatcaa caggtcaaaa tgccctagta
    36721 caggccaaag aattttcgaa aatcacacct ttaacgggaa ttgttttgac taagattgat
    36781 ggaactgctc gaggaggtgt ggttctagcc attcgtgaag aactcaatat tcctgtaaaa
    36841 ttgattggtt ttggtgaaaa aatcgatgat attggagagt ttaactcaga aaactttatg
    36901 aaaggtctct tggaaggttt aatctaatca gaagcaaaaa tcctgcaagg cataaacttg
    36961 caggaaattt ttttattcta agcgaccatc ttgacgatag gtgatatctg gttgccaagt
    37021 ccatttggca ccgaattttt caagtaggtc aaagctggct tgaggtccca tgcttccagc
    37081 tttatagtca tgaagtgggg caccattttc agcccagagc ttttcaatac ggtcaatcaa
    37141 cttccatgac gcacaaactt catcccagtg gctaaagtta gttgagttgt tatttaggac
    37201 atcataaatc aatttttcgt atggttctgg agaagcacca gttgcagtcg catctgtacg
    37261 gtaatcaagt gagttaggag ccaagttaaa ttcttctcct acttgcttcc catttaggct
    37321 aagagagaag ccttctgttg gttgaatata gatggtcaaa atatttggag caagtggttc
    37381 tccaaagata gaatccattt gtttaaagac gatgttgaca tgagttcctt tttcagtcag
    37441 tcgtttacct gtacggaaaa agaaaggaac accacggaat cgatcgctgt ctacaaagaa
    37501 ggcaccagat gtaaaggttt cagttgttga ttctggattc acatttggct cgctacgata
    37561 agagatgtat ttcatgccat caatcttacc agagcggtat tgcccacgga taaagtgttc
    37621 tttgagttct tcgtcagttg gatgatagag gtttttaaag accttaatct tttcagcacg
    37681 aatctcgtct tttgtgaagc ttgctggttt gtccatggcg aggagcgaaa gaagttgtag
    37741 agtgtggttt tggaccatgt cacggagggc accggattgg tcatagtagc caccacgttc
    37801 ttctacaccc aagcgctccg caaaggtaat ttgaacattg tcgataaaat ccttgttcca
    37861 aacgttttca aaaatcaagt ttgcaaagcg aactgcaaag atgctttgga tcatttcctt
    37921 accaagataa tggtcgatac ggaaaatttg ttcttcgtca aatgttgcta ggagttcgtc
    37981 attcaacttg cttgcagttg cgtaatctgt accaaatggt ttttcaacga tcaagcgctc
    38041 aaaacctttg ccatcgacaa tgttttcaga tttgaggtgt ttggcaatgg ttccaaagaa
    38101 ctgaggtgcc atagacaaga agaagagctt attgtgttca gcttggtatt tttcattaag
    38161 ctcagcttgt aattgacgca aagcaatata atgttccgaa tcattgacat catggctttg
    38221 atagtagaag tggctagcaa attcttgggc ttgctcggta ctatctgcca aatcaaggat
    38281 ggactcgaca actacagatt caaaatattc cttactccaa ggtctacggg cagttccaat
    38341 aacggcaaag tgcttggaaa gattgccgga tttatatagt ctaaaaaggg aagggtagag
    38401 cttgcgttta gccaggtctc cactcgcacc gaaaattgta acaataacct tagatgacat
    38461 ctagctacct aatttctatt tttattccta gtcttgctag gtatgaggaa acctcatttc
    38521 ataaacttaa ttctaacata attttccgaa aaatcaaaaa ttccaatacg aagtagaaaa
    38581 actgcaagga aatccttaca gtttgagttt agacgtttaa gaccttatct aagaactctt
    38641 tcagacgagg gtgttgtggg ttatcaaaga tttggtcagg tgttccgtct tcaaggaact
    38701 cgccatctgc agtaaagata acgcggttgg caacctgacg agcaaatccc atctcatggg
    38761 ttacgataat catggtcatg ccttgctcag ccaattcctt cataacgtta agtacgtctc
    38821 caaccatctc agggtcaagg gcagaagttg gttcatcgaa gagcatgatg tctggattca
    38881 ttgctaggcc acgagcgatg gccacacgtt gtttttgacc acctgatagg ctatctggat
    38941 tggcattagc tttatctgct agtccaacct tttcaagcaa ctccattccc aattcctcag
    39001 cttcttcctt agtcatcaac ttgtgctcaa taggagcaaa ggtgatgttg tccaatacag
    39061 acatatgagg gaagaggttg aagtgttgga ataccatgcc gatattttca cggacgtggt
    39121 caacattggt tgttttttca gttaaatcat agccgttcac agtgatgtga ccgctagtga
    39181 cttcttctaa aagattgagg ctacggagga aagttgactt accagaacct gaaggaccga
    39241 tgatacaaac aacatctcct tcatagaact tagtcgtaat tccttttagg acttcatttt
    39301 ttccatagtg cttgtgtaaa tcatttacat caatttttaa ttttgccatt aacgaatcct
    39361 cttttctaag cgtttcgcta gtctagtcaa aagtgtgata attacaagat agaagatagc
    39421 aaggattgca tacatcttga aactttggta gttacgagca atgataatct taccagtttg
    39481 gaagagttca accaaaccga tagcagatac gatagttgta tctttaagag cgataacgaa
    39541 ttggttgaca aagtttggca acatcaattt agttgcttgt ggcaagataa tcttacgcat
    39601 ggtttttcca taagagatac ccaagcttcg gctggcttcc atttggccaa ctggaacggc
    39661 ctgaatacca ccacgaacga tttcagcgat ataagcagcc gcattgagtg agagggcaat
    39721 ggttccagct acaaagtcgt taattgggct ttgttggcct gtgatagact cgatgaagtt
    39781 tggaattccc cagaagatga aggctgcaag aatcatcaat ggaataccac gaataacgtc
    39841 aacgaaaatc tcagagatga tgcgaagaga tttgtatggg ctaacgctaa acataccgaa
    39901 gataattccg atgacaatgg caatagcaaa tgagataaga gctagagcaa gagtgatacc
    39961 aagaccgcta aggagttgtt tgtagttgtt ttgaagcaag ccccagagcg ttgtttcgtc
    40021 aacagtactt gttgaagcag ttgaagattc gctagctagg tatttgtcaa gaatcttttg
    40081 gaattcaccg tttgctttaa ggtttgcaag tccgttgttg aacatttcaa tcagttctgg
    40141 atttgctcct tttttaacag caaaggctgt ttcaccgatt ggagttccag agattggagt
    40201 tttcaatttt tgaccttggc tgatagaata tttgagaaca ggttcatcat ccataacggc
    40261 atcaatggca ccagtgttta aactgtcata cattgaagaa ccatcagcaa aggttttgat
    40321 tttgtaaccg tatttgcttt gattttctgt taggaaggtt tgagaagcag ttccgttttt
    40381 aacaccgact gtctttcctt ttagatcttc ataagaagca atattgcttg attctttgac
    40441 accaagaatg gtattagcag tgtagtatga ttctgagaag tcaaaagttg ccttacgagc
    40501 atctgtgaca gacataccag caatgatacc atcggcttga ccagcttgga cagcactgat
    40561 agcagcatca aaaccagggt tggtgatttc aatttcaaaa ccttggtctt tagcgattgc
    40621 cttaatcaat tccatatcaa taccagtgta ttggttgctt gaattttgga aaacaaaagg
    40681 tgcaaaagaa gaatcgctgg caatgatata tttagcctta acaggaatag cttttaatcc
    40741 tgcgagagta gttgtagttg gcactgctga agatgatgaa gcagtccatt tcttgataat
    40801 tttatcaaga ctaccatctt ttttcatttc agacaaggct tggttaaatt cagtaaccag
    40861 gtgctcgtat ttacttcctt ttttcacacc gaaagcaaaa cttcctacag cttcaccatc
    40921 catttcaata tggaggtctt gaccttggtt aatggcatat tcgataacag gtttgtcatc
    40981 catcatggca tcgatggcac cagcactcaa gctgttgttc attaaatcac cagtgtcaaa
    41041 tgttttaata gtaaagccgt atttatcttt gattgtttca aggaaacgtt gagcggcagt
    41101 tccgttttta acaccaacgg ttttgccagt taattggtcg tacttgctaa ttttgtgtga
    41161 ctttgtagta gcaatgacaa cttttgtatc atagtaagta tcagacatgg tgaagacttt
    41221 ttcacgttct ttagtctttg tcatccctgc catgatagcg tcggcttgcc cagcttgaac
    41281 cgcgttgact gctgcgtcaa atccaggata ggacatctga atgttccagc ctttaatctc
    41341 agcgactttg ttaataatgt caacatcaat tcctttataa gtttgatctg aatctttaaa
    41401 ctcaaaaggt gcataggcag tatcagaaac aatcttaatc gtttctgctt tggcaatacc
    41461 taatgagaaa attgggaata aaattagcaa aaatgctaga aattttttct tcatttttag
    41521 tctccttttc cgaatattct ctcattatat cagaaaaagt aaaaaaaggc aaatttttat
    41581 atttttcgtg tcagaaaata taacattgat ttttcctttt ctttcttgaa ttgctattaa
    41641 aaagt
//
LOCUS       DAVDHZ010000013        40838 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000013 DAVDHZ010000000
VERSION     DAVDHZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.013"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(335..1522)
                     /locus_tag="VUR46_000886"
     CDS             complement(335..1522)
                     /locus_tag="VUR46_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET5456339.1"
                     /translation="MKKIVFASALALTLAGAVLTNDVFANDRLVATQSTDSNVLTSEV
                     LKPSSGNVLVGIKGEFLPPHQQSILDAINKIRKEAADEGLVDKYVPVKWSVDHEKTAF
                     VRAAEVSVTLKAERLSSKNNWTAFPSGNSLSGEALDLNPDGFLKAIENWHAEKANYVA
                     KKKDKTSKEFSFYYENLINPKFTYVGLAAFKNAASPQKAATVALALGTTTSSEELAGG
                     YGSAVQYTEVTASNLSTVKSKAMVVETPLKDFRKSTSDQSGWVQSNGKWYFYESGDVK
                     TGWLKTGGKWYYLNDLGVMQTGFVEVDGSVYYLSNSGAMFTGWGTDGSRWFYCDGSVA
                     MKTGWYKENGTWYYLDEEGIMKTGWFKVGQHWYYANGSGALAVSTTTPDGYRVNANGE
                     WVS"
     gene            complement(1821..2987)
                     /locus_tag="VUR46_000887"
     CDS             complement(1821..2987)
                     /locus_tag="VUR46_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET5456340.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDC
                     NLLLLQPAASNDAGFAMTSSFMSMMLTALLVFDPIEFAVKSERFEVVSSLARKVLDNA
                     EDVKELVDLDFKRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INEDTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            complement(3285..3677)
                     /locus_tag="VUR46_000888"
     CDS             complement(3285..3677)
                     /locus_tag="VUR46_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5456341.1"
                     /translation="MTKSLILVSHGRFCEELKGSTGPQDNIYTVALLPEDGPEEFTAK
                     FEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINASLTGA
                     DADYKSRAAESIVKVNDLLADFDDDEDE"
     gene            complement(3684..4499)
                     /locus_tag="VUR46_000889"
     CDS             complement(3684..4499)
                     /locus_tag="VUR46_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5456342.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            complement(4486..5391)
                     /locus_tag="VUR46_000890"
     CDS             complement(4486..5391)
                     /locus_tag="VUR46_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5456343.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            complement(5419..5895)
                     /locus_tag="VUR46_000891"
     CDS             complement(5419..5895)
                     /locus_tag="VUR46_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET5456344.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            complement(5892..7679)
                     /locus_tag="VUR46_000892"
     CDS             complement(5892..7679)
                     /locus_tag="VUR46_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET5456345.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPASLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEDDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHCYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            8027..8743
                     /locus_tag="VUR46_000893"
     CDS             8027..8743
                     /locus_tag="VUR46_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5456346.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            9060..12995
                     /gene="strH"
                     /locus_tag="VUR46_000894"
     CDS             9060..12995
                     /gene="strH"
                     /locus_tag="VUR46_000894"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET5456347.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVNSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESACTVDLGNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAYP
                     LSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRQSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(13050..14348)
                     /gene="purB"
                     /locus_tag="VUR46_000895"
     CDS             complement(13050..14348)
                     /gene="purB"
                     /locus_tag="VUR46_000895"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET5456348.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(14411..14638)
                     /locus_tag="VUR46_000896"
     CDS             complement(14411..14638)
                     /locus_tag="VUR46_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET5456349.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            complement(14648..15739)
                     /gene="purK"
                     /locus_tag="VUR46_000897"
     CDS             complement(14648..15739)
                     /gene="purK"
                     /locus_tag="VUR46_000897"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET5456350.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            complement(15726..16214)
                     /gene="purE"
                     /locus_tag="VUR46_000898"
     CDS             complement(15726..16214)
                     /gene="purE"
                     /locus_tag="VUR46_000898"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET5456351.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            complement(16617..17879)
                     /gene="purD"
                     /locus_tag="VUR46_000899"
     CDS             complement(16617..17879)
                     /gene="purD"
                     /locus_tag="VUR46_000899"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET5456352.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            complement(18001..19548)
                     /gene="purH"
                     /locus_tag="VUR46_000900"
     CDS             complement(18001..19548)
                     /gene="purH"
                     /locus_tag="VUR46_000900"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET5456353.1"
                     /translation="MTKRVLISVSDKVGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            complement(19573..20082)
                     /locus_tag="VUR46_000901"
     CDS             complement(19573..20082)
                     /locus_tag="VUR46_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET5456354.1"
                     /translation="MLESKQTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            complement(20166..20711)
                     /gene="purN"
                     /locus_tag="VUR46_000902"
     CDS             complement(20166..20711)
                     /gene="purN"
                     /locus_tag="VUR46_000902"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET5456355.1"
                     /translation="MKKIAVFASDNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            complement(20708..21730)
                     /locus_tag="VUR46_000903"
     CDS             complement(20708..21730)
                     /locus_tag="VUR46_000903"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET5456356.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            complement(21767..23209)
                     /locus_tag="VUR46_000904"
     CDS             complement(21767..23209)
                     /locus_tag="VUR46_000904"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET5456357.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            complement(23302..27027)
                     /locus_tag="VUR46_000905"
     CDS             complement(23302..27027)
                     /locus_tag="VUR46_000905"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET5456358.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            complement(27229..27936)
                     /locus_tag="VUR46_000906"
     CDS             complement(27229..27936)
                     /locus_tag="VUR46_000906"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET5456359.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            complement(28106..29455)
                     /locus_tag="VUR46_000907"
     CDS             complement(28106..29455)
                     /locus_tag="VUR46_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET5456360.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            complement(29468..31621)
                     /locus_tag="VUR46_000908"
     CDS             complement(29468..31621)
                     /locus_tag="VUR46_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET5456361.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            complement(32001..32492)
                     /locus_tag="VUR46_000909"
     CDS             complement(32001..32492)
                     /locus_tag="VUR46_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456362.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            complement(32473..33069)
                     /locus_tag="VUR46_000910"
     CDS             complement(32473..33069)
                     /locus_tag="VUR46_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5456363.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(33066..33548)
                     /locus_tag="VUR46_000911"
     CDS             complement(33066..33548)
                     /locus_tag="VUR46_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HET5456364.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
     gene            complement(34692..34988)
                     /locus_tag="VUR46_000912"
     CDS             complement(34692..34988)
                     /locus_tag="VUR46_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HET5456365.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(35531..36424)
                     /locus_tag="VUR46_000913"
     CDS             complement(35531..36424)
                     /locus_tag="VUR46_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5456366.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKDSLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNVAEAESFYEKAISLAEL
                     LDDQVLVQKILAEKQIDFPTT"
     gene            complement(37178..37408)
                     /gene="blpU"
                     /locus_tag="VUR46_000914"
     CDS             complement(37178..37408)
                     /gene="blpU"
                     /locus_tag="VUR46_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET5456367.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(37611..37901)
                     /locus_tag="VUR46_000915"
                     /pseudo
     CDS             complement(37611..37901)
                     /locus_tag="VUR46_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(37947..38180)
                     /locus_tag="VUR46_000916"
     CDS             complement(37947..38180)
                     /locus_tag="VUR46_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET5456368.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(38186..39178)
                     /gene="plsX"
                     /locus_tag="VUR46_000917"
     CDS             complement(38186..39178)
                     /gene="plsX"
                     /locus_tag="VUR46_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET5456369.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(39175..39945)
                     /gene="recO"
                     /locus_tag="VUR46_000918"
     CDS             complement(39175..39945)
                     /gene="recO"
                     /locus_tag="VUR46_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET5456370.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(39942..>40838)
                     /locus_tag="VUR46_000919"
     CDS             complement(39942..>40838)
                     /locus_tag="VUR46_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5456371.1"
                     /translation="NEILVTIGATEALSATLTAILEEGDKVLLPAPAYPGYEPIVNLV
                     GAEIVEIDTTENGFVLTPEMLEKAILEQGDKLKAVILNYPANPTGITYSREQLEALAA
                     VLRKYEIFVVCDEVYSELTYTGEAHVSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFA
                     PAAFTAQLIKSHQYLVTAANTMAQHAAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTA
                     LGFEIIKPDGAFYIFAKIPAGYNQDSFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLS
                     YAASMETIKEAMKRLEEYMREA"
BASE COUNT        12458 a         9275 c         7500 g        11605 t
ORIGIN      
        1 cgatagaaat ttctattgaa atatacttaa aaatatactg caatttttta tagaagaata
       61 caatgaactg caacaataga aaacggaaac aaaatctaga caaataagtg aggagtttca
      121 aactaattac agtatttttt aattagatta ccgattatgc ttttaatata ctataaaata
      181 ttagctcata atagaaaagt ctgagattga agcgacaaag aatccaatct ttataaacca
      241 aaagaggtca atgtctgcca tcaacctctt tcttatattt cattcttttt gctaagtaag
      301 atgaatactt tacctatgac ttgctctttt cagcctagct tacccattca ccattagcat
      361 ttacacggta accatctggt gttgttgtgc taacagccaa agcgcctgaa ccatttgcat
      421 agtaccagtg ttgacctact ttaaaccaac ccgtcttcat gatcccttct tcatcaaggt
      481 aataccatgt accattttcc ttgtaccagc ctgttttcat agctactgag ccatcacagt
      541 agaaccatct gctaccatct gttccccagc ctgtaaacat agcgcctgag ttacttagat
      601 aatacaccga tccatcaact tctacaaatc cagtctgcat aacacctagg tcattcaagt
      661 agtaccattt accacctgtt ttcaaccagc ctgtcttcac atcaccagac tcataaaaat
      721 accacttgcc attagactgc acccagccag actgatcaga cgtagatttt ctgaaatctt
      781 tcaacggtgt ttctacaacc attgctttac ttttaactgt tgaaaggttt gaggcagtca
      841 cttctgtgta ctgaacagca gaaccatatc caccagccaa ttcctctgaa gaagtcgtag
      901 ttcctagagc caaagcaacg gttgctgcct tctgaggact agctgcattt ttaaaagcag
      961 caagacccac ataggtaaat ttagggttaa tcaagttctc ataataaaat gaaaattctt
     1021 ttgatgtttt atctttcttt ttcgccacat agttcgcctt ttcagcatgc caattctcaa
     1081 tggcttttag aaatccatca ggattcaaat ctagggcttc tccacttagg ctattaccag
     1141 atggaaatgc agtccagttg tttttactgg aaagacgttc agccttcaac gtaacggata
     1201 cctcagcagc gcgtacaaaa gccgttttct catggtcaac tgaccatttg acaggaacat
     1261 acttatctac caaaccttcg tcagctgctt ctttacgaat tttattaatg gcatctaaaa
     1321 tagattgttg atgaggaggc aaaaattctc ctttgattcc aaccaaaaca ttgccactag
     1381 aaggttttag cacctctgag gtcaatacat tactatcagt agattgtgtt gcaaccagtc
     1441 tgtcattcgc aaaaacatca tttgtcaaaa ctgctcctgc caaggtcaag gccaaggcgc
     1501 tagcaaatac aattttcttc atttctttct tactccttat tgtagtttga atattatctt
     1561 aacagatacc ttttctctca atcaaacaaa ccatagaaag cgaattgaca atctatggtt
     1621 tgcctgatga tgtacaaatc ctcttgtcaa gaattcataa acactgtctt atactcaatg
     1681 aaaatcaaag agcaaactag gaagctagcc gcaggctgct caaagcactg ttttgaggtt
     1741 gtagatagaa ctgacgaagt cagtaaccat acctacggca aggcgacact agtatggttt
     1801 aaagagattt tcgaagaata ttacttttga tattcgtgga tgataacacc ttgtaccaca
     1861 cggtttacgg tacctgtagg agacggtgta tctggtttat tttctacctt gagtgaagtc
     1921 aatagagcaa agagttgagc atatacgatg tatgggaaga cacggtaaat atcattcaag
     1981 acaccgccac aaccaagggc cacttctttg acattttcaa gaccaaaggc ttgatcactc
     2041 aaaagcacaa cacgacgagc aatctggtca ccagcaactt cacgaaccaa gtctaagtcg
     2101 tacttgcgag tgtagtctgt cgttgtacca aagaccaaga caactgtatc ttcgttgata
     2161 agtgattttg gaccgtgacg gaagccaact ggactttcat acatagtcgc aacttgacca
     2221 gctgttaatt ccaaaatctt gagctgagct tcatgagcaa gcccaaagaa aggaccagcg
     2281 cctaggtaga tgacacgctt aaagtctagg tcaacaagct ctttgacatc ttctgcattg
     2341 tctagaactt tacgggcaag actagaaaca acttcaaaac gttcagattt cacagcaaat
     2401 tctataggat caaagaccaa gagagctgtc aacatcatag acataaagct agaagtcatg
     2461 gcaaatccag cgtcattaga agcagctggt tgcaagagca agagattaca gtcatcaccg
     2521 tgagcttgaa gagccaattt accatctgct gcacaagtaa tcgtcacttg ataaagctca
     2581 tccaccaagg atttggccaa atcaacagtc gccacacttt caggcgagtt cccactacga
     2641 gcaaaagaca caaggacagt tgccacatct tttttcaaat aggttgctgg attggcaacg
     2701 atatctgttg ttgcaatggc attgaaattc catttgcgtt cgtcatagac ttccttaaag
     2761 taaggtagca aggtatctcc cacataagca gaagtcccag cacctgtcaa gataacctta
     2821 atatagtcat gtttatcagc gatttcttgt aggaaggctg caatttcttc acgttttgct
     2881 tgataaaatt caaaagcttc tctccataca tcaggttgtt ggtagatttc acgcgtagtg
     2941 atttctgcac ccaattcgag caagtcttct tttgtataat gtagcattga gttcctcttt
     3001 ttctattaaa tatgggaatg ggagtaagct ccattcccat gtatattcta tataaaatgc
     3061 tctaacgatt ttcacgttgt cacatgaatt gaatcgagtt ccaactaaaa tctgtaggaa
     3121 actagccgca ggctgctcaa agcactgctt tgaggttgcc ggataagact gacgaagtca
     3181 gctcaaaaca ccgttttgag gttgcagata gaactgacga agtcagtaac atatacctac
     3241 ggcaaggcga cgttgacgta gtttgaagag attttcgaag agtattattc atcttcatca
     3301 tcatcaaaat ccgctaacag gtcattaact ttcacaatgc tttctgcagc acggctcttg
     3361 tagtccgcat ctgcgcctgt aaggctcgca ttgataaatt caatcaccat tggaagattc
     3421 atccctgcgt aaaggtcaat atcacgacct tccatgatca agcgactcac cacattacaa
     3481 ggtgtcccac cgagaagatc cgcaaagact aggaaatcat ccaacccttc aataacagct
     3541 tcaaatttag cagtaaattc ttctgggcca tcttctggaa gaagagctac tgtgtaaatg
     3601 ttgtcttgtg ggcctgtgct acctttaagc tcctcacaga agcgaccatg gctcaccaaa
     3661 attaatgatt tagtcataag gaattacatt ccaagtgcaa agtgaccaag ggcagaaaga
     3721 gccaaagcaa gtacgataat aataccgata gctttagtag agttcatacc ttttttacca
     3781 agcaaccaga agataaaggc agtaaagatt gctggaagca aacgtgggaa gatttggttc
     3841 aagatgtctt ggaaatcaat catcttttca ccgattggca acttgtaaga aatttcaaag
     3901 ttaatcactg ttgctacaag agcacccatc atgaagacac caagtacaga tgcagcgtca
     3961 atcaaagctg tcaaggtact ttgcatgttg ttgataaggt taaccccttc tttgtaagca
     4021 aattccaact gtttccaacg gaagatgtca tacgctactg caactgcaat ccaaaggaag
     4081 atcccccaag gttggccagc gatagccata gttgctgcga ctgaccccat gatagcaggt
     4141 acaagtgaac caaagattgt atccccaaga ggagcgaatg gtcccatcaa acctgtcttg
     4201 ataccgttaa cagcgtcttt tgaacctaca ccatcttttt cttccatggc aaggtcaaaa
     4261 ccagcgataa tggtatggaa gaatggtgaa gtattgaaga attgagtatg aactttcatc
     4321 atttctttca attcaggagt tccatcacca tacattttac gcaactgagg caagatcatg
     4381 taaaggtaac cagaagcttg catacgttcg tagttccaac ctaattggaa agtaaacaag
     4441 ctacgtttgt tgatttgatt aaaatcttct tttgtaagtt tgtaattaga attcgtcatc
     4501 ttcgatttcc ccactttctg atggtgtaga aggtgctgct acagctactt tttggctatt
     4561 tttgaagtga agcactgcaa ggaaaatacc tacgatagaa ataccaatca tagacaaacc
     4621 tttgaagttg ttcacgaaac caattttttc agcaacttca gcaggaagag tacctacgat
     4681 accagcaaca gcgccaccaa gacctgttac atatgagtaa agaacagtca acatagctgt
     4741 caaaccaaat cccatagcaa ggtagtgaag gttacgttta actggaaggt aacgaagcaa
     4801 gattgcaaat ccaagacctg gaagcatacg tcctgcgagt gtcaagccat ctgcaaccca
     4861 tttgtaggct tcaacgaagt ctactactga ttgtacaaag gcaccaccaa aagcaagggc
     4921 aaagaagact ggaagggcac gagatagagc ccacggaatc gcaccaagca agtagttgcg
     4981 ttcaatacct ttatagtcaa agcgttcgat tgcagcatcc acacggtgag cgaagaaggt
     5041 agtagtcata cgaccaagaa cgtcgaagta agtcaagaga gctgctactg gtacagcgat
     5101 tgtagtaatt gcaagcggtg catcaattcc ttgtgaaaca gagaaggctg tcgcaagaac
     5161 cgcaccagaa gttgcgtcga tacgagaagc accaccgaag gtaccaaccc caagaacgaa
     5221 cagttgcaag ttaccaccga taagtaaacc agtagtcaca tctcccatga ttaaaccagt
     5281 aatgaaacca gcaaatacag gggaacctgc agatgaaacg atcgtcaact catcacagat
     5341 ttgataagct gagtacaaag tgagaagtaa aatttgccac cattgtatca taacaatgac
     5401 ctcctaaaaa tttttttcct attttaataa gctcaaaaag tctgaaattg gatcatttgg
     5461 aaccatctga gcagtaagtt taacaccttt ttctgccagt ttgtggaagt cttccacatc
     5521 cttgtctact acgttgatag aacgtgtaat agaacgagtt tctggtgttt gagacatatt
     5581 cccaacatta agagtttcaa gtggtacacc tgcttctacc aaaccaagga agcggtccgg
     5641 tttacgagcc acgataaaga gacgttggct atcgtatttg ccagcaagaa tattggctgc
     5701 agctttctca actggcaaaa tactcaattt cacacctggt ggtgtcgcaa gtttcaaacc
     5761 actcttttca atatcgttgt tgacaacttc gtcgtctaca accataatgc gtgaaacatt
     5821 tagttttcca gcccaaagat tggctacttg tccgtggatc aaacgtccat caatacggca
     5881 tcctacaatt gtcataagtt ttcccccttt atatgtttta gtgtaggttt acgagttaaa
     5941 tgaatctctt ctttatattg accttctgtt tcaaagataa tgatgcggtt ggcaccttcc
     6001 ttgagatagc aatgagggat ataaagtgag agagttgggc caacgttcca aaaacgtcct
     6061 agattctgcc cattgacaaa ggcaactccc ttaccaaact cagacaagtc taggtaagta
     6121 tcttttggct cttcgactgt aaagtcataa gcgtaaaagg ctggttgtcc ttgagtccat
     6181 ccttttgaaa aatcaatttt ctcaggattg tctagtggga gtggatagtg tttccagttt
     6241 agtaagaaat gcagatcctt acagacccct gtccgaattc ccttacgttg cgtatccgct
     6301 aagaacttat gcccatagtt gacacgcccc atattttcta tcaagatatc taacctagat
     6361 agccctttct ttttaccttg ataaaaaata tcttccccaa tctctgtctg atattgagtt
     6421 ttaacccact gaccatcgac atacagctga gccctatctc gaccatcaat gatacgaagt
     6481 ctttcttctt ctgcatccca gtttgtttct gttcgataaa gtaggtagcc ataactttgt
     6541 cccagctcct ccatcttttg aggatagaga ctttctacag gacttgacaa gctatctaag
     6601 gtttcaaaca aagaaacttt ttcaactagt ggaatagcat ccaactccat actctctttg
     6661 tagagtggtt ccaactgcgg atactctgaa aaatgtgttg ccatcatctt cttgactgca
     6721 agatatttag cagttggatt tccttcttca tccagaaggg catcgtaatc ataagacgta
     6781 acttgtggca ggtccaaagt tcctcgagct gagcaaccat tcatgaaacc aaagtttgta
     6841 ccaccgtgga acatgtaaag attgatagag ccttgttcca aaacctctcg aactgcatct
     6901 gccaattcct taggatcccg tgtgataatc ggttctttcc agcgattaaa ccaaccatcc
     6961 cagaactcca tacacatgag tggccatttc ttcccatgtt catcaaagaa ttcctgcatc
     7021 tgtgaaaagt tgtaaggtgc cttagaacca aagttccctg ttacaaagag atcatcttct
     7081 attaaggttc cagctttcag agttgctctc catggaccat ctgatgtaaa gagtggacag
     7141 gttacgccac gctcttccat caactgtcga atcgctctca ggtaagcctt atcttctccg
     7201 taagaaccat actcattttc aacctgcatc atgagaatat tgccaccatt gtccaacaaa
     7261 cgaggcacca gtcttggcaa taactgatca tagtagcgac caactgcctc gatatatgct
     7321 gggtcggatg agcgaattcg catgttcttg gtcaagagcg aagctggtaa gccaccgaat
     7381 tcccattccg cacagataaa tggagacgga cgcacaattg cgtagagacc caaatcctgc
     7441 gctatttgga gaaatttctc taaatccaga tcaccttcaa aatgaaactc accttcacga
     7501 ggctcgtgta aattccaagc aacataagtc tctaccgtat taaaaccaag agccttcaag
     7561 ttatagagcg aatgatacca atcctctgga ggaaccctaa aataatgaat ggcaccagat
     7621 aaaatcttaa atgattttcc atcgagatag aaatcatctc gtatctcaaa tcgtgtcata
     7681 aaactacctt ccgaccgcga aagtttgcgc tttcatttgt tgttatatta attataaacc
     7741 aatctgtttg aattgtcaat agaaattgtc gggatattta ctgcattttt actattatac
     7801 acacattcaa ttagtttcaa acatttttag acccatttca aacgctcttt aaattcggaa
     7861 tataggacct aaaataattt tgtatagaat acattgataa aatatgagca atccctatat
     7921 cgcttaattt ttcaaactat tattctaatt ttttattcaa aagactacta tttttttcgc
     7981 ttttatggta aaattttcta tggagaagga aaatagaggt aaaaatatgg caattcccaa
     8041 atatcaatac ataaaagacg aattaaaaaa taaaatcatc tctgggcagt ttagcagtgg
     8101 agataaattt tacactgaag cagaactcat ttcaatgtac gatgtcagct ctatcacagt
     8161 tgttcgcgcc ttaaacgacc ttgccaaaga tggctatatt gtccgccaac aaggaaaagg
     8221 aaccttcgtt tcacgtgcac gcaaacacaa gcttgtagag ttttcagata ttgaactctt
     8281 caatgctaaa gatgataagg taactgttct ttcaattgaa cgcggaaaca agcttgttta
     8341 cttggaaaaa ttgggtctac gcggcgatca attctactac aagattgaac gtatccgcga
     8401 atcaaacggt gtcgtttata tctaccatac atcctacatc ccagaacaat atatcaatgc
     8461 aaattatcca aaccttgaat actatagttc tatctataat cgtttcaagt tagactacca
     8521 cattcacatg aatgatgaac actttgaaga aatcaacgaa atagtctttc caactccaga
     8581 acatgcggct tcagtcctcg gagtcgatga acaattccct actgtcctac aaactaaaat
     8641 caccaaactc gaatcaactg gccaagtttt agaatacagt gaaacttaca aacgatctga
     8701 ttactacaag attaaattca tctcatgtga ccgtgatcac taagaagaaa gcctgagcct
     8761 aatcgctcgg gctttttcta tgcttattat accacaccaa aaaggtagcg cttacttatt
     8821 tttggaagat tctataattt gtggaatatt ttatagaaat agaaccaaaa attatattag
     8881 atatatatat gcattttttt ccgaccaatc tgaaatctta agtttaaatt ttatattttt
     8941 ttatacttat tatagttttt tgtcatctcc tcttgactct cgttaatata agaaataaaa
     9001 taagggcgtt gatttatata atcgctatca atataacaat gcaatcagga ggttttgcaa
     9061 tgaaacatga aaaacaacag cgtttttcta ttcgtaaata cgctgtagga gcagcttctg
     9121 ttctaattgg atttgccttc caagcacaga ctgttgcagc cgatggagtt actactacta
     9181 cagaaaacca accgaccatc catacagttt ctgattcccc tcaatcatcc gaaaatcgga
     9241 ctgaggaaac acctaaagca gagcttcaac cagaagctcc aaaaactgta gaaacagaaa
     9301 ctccagctac tgataaggta gctagtcttc caaaaacaga agaaaaacca caagaggaag
     9361 ttagttcaac tcctagtgat aaagcagagg tggtaactcc aacttctgct gaaaaagaaa
     9421 ctgctaataa aaaggcagaa gaagctagcc ctaaaaagga agaagcgaaa gaggttaatt
     9481 ctaaagagtc aaatacagac aagactgaca aggataaacc agctaaaaaa gatgaagcga
     9541 aagcagaggc tgacaaaccg gaaacagagg caggaaagga acgtgctgca actgtaaatg
     9601 aaaaactagc gaaaaagaaa attgtttcta ttgatgctgg acgtaaatat ttctcaccag
     9661 aacagctcaa ggaaatcatc gataaagcga aacattatgg ctacactgat ttacacctat
     9721 tagtcggaaa tgatggactc cgtttcatgt tggacgatat gagcatcaca gctaacggca
     9781 agacctatgc cagtgacgat gtcaaacgcg ccattgaaaa aggtacaaat gattattaca
     9841 acgatccaaa cggcaatcac ttaacagaaa gtcaaatgac agatctgatt aactatgcaa
     9901 aagataaagg tatcggtctc attccgacag taaatagtcc tggtcacatg gatgcgattc
     9961 tcaatgccat gaaagaattg ggaatccaaa accctaactt tagctatttt gggaaggaat
    10021 cagcctgtac tgtcgatctt ggcaacgaac aagctgtcgc ttttacaaaa gcccttatcg
    10081 acaagtatgc tgcttatttc gcgaaaaaga ctgaaatctt caacatcgga cttgatgaat
    10141 atgccaatga tgcgacagat gctaaaggtt ggagtgtgct tcaagctgat aaatactatc
    10201 caaacgaagg ctaccctgta aaaggctatg aaaaatttat tgcctacgcc aatgacctcg
    10261 ctcgtattgt aaaatcgcac ggtctcaaac caatggcctt taacgacggt atctactaca
    10321 atagcgacac aagctttggt agttttgaca aagacatcat cgtttctatg tggactggtg
    10381 gttggggagg ctacgatgtc gcttcttcta aactactagc tgaaaaaggt caccaaatcc
    10441 ttaataccaa tgatgcttgg tactacgttc ttggacgaaa cgctgatggc caaggctggt
    10501 acaatctcga tcaggggctc aatggtatta aaaacacacc aatcacttct gtaccaaaaa
    10561 cagaaggagc tgatatccca atcatcggtg gtatggtagc tgcttgggct gacactccat
    10621 ctgcacgtta ttcaccatca cgcctcttca aactcatgcg tcattttgca aatgccaacg
    10681 ctgaatactt cgcagctgat tatgaatctg cagagcaagc acttaacgag gtaccaaaag
    10741 acctgaaccg ttatactgca gaaagcgtca cggccgtaaa agaagctgaa aaagctattc
    10801 gctctctcga tagcaacctt agccgtgccc aacaagatac gattgatcaa gccattgcta
    10861 aacttcaaga aactgtcaac aacttgaccc tcacgcctga agctcaaaaa gaagaagaag
    10921 ctaaacgtga ggttgaaaaa cttgccaaaa acaaggtaat ctcaatcgat gctggacgca
    10981 aatactttac tctgaaccag ctcaaacgca tcgtagacaa ggccagtgag ctcggatatt
    11041 ctgatgtcca tctccttcta ggaaatgacg gacttcgctt tctactcaat gatatgacca
    11101 ttactgccaa cggaaaaacc tatgctagtg atgacgttaa aaaagctatt atcgaaggaa
    11161 ctaaagctta ctacgacgat ccaaacggta ctgcactaac acaggcagaa gtgacagagc
    11221 taattgaata cgctaaatct aaggacattg gtctcatccc agctattaac agtccaggtc
    11281 acatggatgc tatgctggtt gccatggaaa aattaggtat taaaaatcct caagcccact
    11341 ttgataaagt ttcaaaaaca actatggact tgaaaaacga agaagcgatg aactttgtaa
    11401 aagccctcat cggtaaatac atggacttct ttgcaggtaa aacaaagatt ttcaactttg
    11461 gtactgacga atacgccaac gatgcgacta gtgcccaagg ctggtactac ctcaagtggt
    11521 atcaactcta tggcaaattt gccgaatatg ccaacaccct cgcagctatg gccaaagaaa
    11581 gagggcttca accaatggcc ttcaacgatg gcttctacta tgaagacaag gacgatgttc
    11641 agtttgacaa agatgtcttg atttcttact ggtctaaagg ctggtgggga tacaacctcg
    11701 catcacctca atacctagca agcaagggtt ataagttctt gaataccaac ggtgactggt
    11761 attatgttat aggcaatcac aaacaagatg aagcttaccc tctttcaaaa gcagttgaaa
    11821 attctggtaa agttccattc aatcaactag cttctaccaa atatcctgaa gtagatcttc
    11881 caacagtcgg aagtatgctt tcaatctggg cagatagaca aagcgctgag tacaaggaag
    11941 aggaaatctt tgaactcatg actgcctttg cagaccacaa caaagactac ttccgtgcta
    12001 attataatgc tctccgcgaa gaattagcta aaattcctac aaacttagaa ggatatagta
    12061 aagaaagtct tgaggccctt gacgcagcta aaacagctct aaattacaac ctcaaccgta
    12121 ataaacaagc tgagcttgac acacttgtag ccaacctaaa agccgctctt caaggcctca
    12181 aaccagctgc aactcattca ggaagcctag atgaaaatga agtggctgcc aatgttgaaa
    12241 ccagaccaga actcatcaca agaactgaag aaattccatt tgaagttatc aagaaagaaa
    12301 atcctaacct cccagctggt caggaaaata ttatcacagc aggagtcaaa ggtgaacgaa
    12361 ctcattacat ctctgtactc actgaaaatg gaaaaacaac agaaacagtc cttgatagcc
    12421 aggtaaccaa agaagttata aaccaagtgg ttgaagttgg cgctcctgta actcacaagg
    12481 gtgatgaaag tggtcttgca ccaactactg aggtaaaacc tagactggat atccaaaaag
    12541 aagaaattcc atttaccaca gtgactcgtg aaaatccact cttactcaaa ggaaaaacac
    12601 aagtcattac taagggcgtc aatggacatc gtagcaactt ctactctgtg agcacttctg
    12661 ccgatggtaa ggaagtgaaa acacttgtaa atagtgtcgt agcacaggaa gccgttactc
    12721 aaatagtcga agtcggaact atggtaacac atgtaggcga tgaaaacgga caagccgcta
    12781 ttgctgaaga aaaaccaaaa ctagaaatcc caagccaacc agctccatca actgctcctg
    12841 ctgaggaaag caaagctctt cctcaagatc cagctcctgt ggtaacagag aaaaaacttc
    12901 ctgaaacagg aactcacgat tctgcaggac tagtagtcgc aggactcatg tccacactag
    12961 cagcctatgg actcactaaa agaaaagaag actaagtctt ttcgataaaa aataaacagc
    13021 gagattgaag ctcgctgttt attttttaat taatcaccta gtccaagacg ttcaaagata
    13081 tcatccactc gtttggtgta ataaactggg ttgaagattt catcgatttc ttcttgagtg
    13141 agacgtgatg ttacttctga atctgcctca agaagtggtt taaagtctac ttggttgtcc
    13201 caagagtagg ctgtttttgg ttgcaccaag tcataggctt gctcacgggt catgcctttt
    13261 tcaatcaatg tcaacatagc ccgttggcta aagataagac caaaagtcga gttcatgttt
    13321 cggatcatat tttctgggaa gactgtcaag ttcttgacga tatttccaaa acggttgagc
    13381 atgtagtcaa tcaaaatggt cgtatctggt gtgatgatac gctcagctga tgagtgagaa
    13441 atatcgcgtt cgtgccagag agcgacgttt tcataagccg taatcatgtg accacgaatg
    13501 acacgcgcca gaccagtcat attttcagaa ccgattgggt tgcgtttgtg aggcattgct
    13561 gaagaccctt tttgcccttt agcaaagaac tcttctactt cgcgttgctc agatttttgt
    13621 agaccacgaa tctcagtcgc catacgttcg attgaagtcg caatgctggc aagaaccgca
    13681 aagtactcag cgtgaaggtc acgaggaagg acttgtgtag agatttcttg ggcacggatg
    13741 ccaagtttat cgcagacata ctcctctaca aatggtggga tattggcaaa gttcccaacc
    13801 gcaccagaaa tcttaccagc ttctacacca gcagctgcat gctcgaaacg ctcgatattg
    13861 cgtttcattt cgctgtacca agttgccaat ttaagaccaa aggttgtcgg ctcagcgtgc
    13921 acaccatgag tacgccccat catgatggtg aacttgtgct ccttggcctt gtcagcgatg
    13981 atattagtga agttttcaag gtcacgacgg atgatgtcgt tggcctgctt gtagaggtaa
    14041 ccataagcag tatccaccac gtcggtagaa gttaacccat agtgaaccca cttgcgctct
    14101 tcaccaagag tctcagaaac cgcacgcgtg aaagccacca catcgtggcg cgtctcctgc
    14161 tcaatttcca aaatacggtc gatgtcaaag tccgccttct tgcgaatcaa agccacatct
    14221 tccttaggga tttcccccaa ctcagcccat gcctcgtcag agaggatttc cacctcaagc
    14281 caagcacggt atttattttc ttcactccaa atattcgcca tctcagggcg agagtaacgg
    14341 ttgatcatgt gttaattttt cctttcttct taagctgttg ggaataagct atctaggtaa
    14401 accaagattt ctactcaaac tcctcttttt caataaacac agacgggtaa tgatctagtg
    14461 tattcaaatc cgtatccagc ggtacatcat agatagctaa ataattttcg gggtattgtg
    14521 cagctagttc ttcatattta gcttgtacct tatcttggtc agcactggca tacaacactt
    14581 caacaactgc tccagtctta tccttttcaa taaatgtatt aacgataatt tgtatcatag
    14641 acttgtccta aaaatcaatc ccttccccaa actcttccac actatccggc acatcactaa
    14701 acaaagtcac atgtcccatc ttacgattat gctttgcttc tattttacca tacatgtgga
    14761 ggtgggcgct tgaattttct gtcacatatt gctcagcagc ctcgacatgc tgaccgagga
    14821 cattaagcat aacggctggc gcatggagtt tgatgactgg taatggtgct ccgagaacac
    14881 ccagaatatg ggtgtcaaac tgagagaaat cacaggcttc aatagaatag tgcccagagt
    14941 tatgtggtcg tggggcgatt tcattgacaa taacgtcatc atcagtcgca aacatttcca
    15001 cacagagagt tccagacaag ttgagttgtt ctgcgattcg cactgccata gctttagcct
    15061 tgtctgctag actttcagaa atgcgggctg gtacgatggt cttagacagg atattgttgc
    15121 ggtggatatt ttcctgaact gggaaaaacg tcacctcctt gccatttcct gacacgatga
    15181 cagaaatctc aaggtcaaag ttgacaaatt cttccaagac gcagtctgct gagtctgcta
    15241 gcgcataggc tgcttccaag tctgcttctg aacgaataac cttttgtcca tgaccatcgt
    15301 agccaccagt cgcagtcttg aggacatagt ttttcgacaa gtcgatatct gccaagtcta
    15361 ggctagaagt cacgaccttg tagggtgcca cagtgacttg agccttgttt gacaaaaagt
    15421 ccttttcaaa aatacgattt tgcgaaatgc ggagcagatc tgttccttga gggagttgtc
    15481 catccttgat aacggcatcc aaaccgtcag cgtcgacatt ttcaaactcg taagtgagga
    15541 catcgcaacg gtctgccaac tgacggaggg cgtccacatc gttataaggt gccacaatga
    15601 tttccgccac gcgagaggcc gggcaatccg ccgcaggatc cagcgcgata accttgtggc
    15661 ccatgtagat agcagaaatg gccatcatct gacccagttg accgccaccg ataattccga
    15721 ttgttttaga tgagctcatt tgacgactcc tctgcgattt ttccttgttc ttcagcaaag
    15781 ttggcaagtg catccgcaat ggacttatct tctacagaga ggagacggag ggcaaagaga
    15841 gctgcgttag tcgctccagc ttcaccgata gccatggtcg caacaggcac cccacccggc
    15901 atctgaacga tagaatagag tgaatccact ccactaagag cacgagactt gactggcaca
    15961 ccaatgactg gaagggttgt tttggcagct accatgcctg gcaaatgcgc tgcgccacca
    16021 gcacctgcga tgatgatctt gatgccacga ctacgggctt cttctgcatg tttgaacatg
    16081 aggtctggtg tacggtgtgc ggaaacaact ttcttttcgt aggctacacc gaagcggtct
    16141 aggacttctg ctgttttttg catggttgcc cagtcggatt ttgagcccat gatgatggaa
    16201 attactggtt tcatttcttc tcctttttcc tctttttcaa caatcacctt agcttgtgag
    16261 ggacggcagc agccaccaaa ggtgtctcat gcctaaattg gaaacccaag gtcttccaat
    16321 ttccctgaac gattggatta tcatccaatc gttctttcac aacggcggtg attgttctat
    16381 attagctcgc taacgatcgc aaaccatacg atcattaacg tattttgtga atttttattt
    16441 ttctttttga taatggtctt aggtgatgga ggcggaagca aaccttcggt ttcattccta
    16501 aactttgagc ctaaggtctc caagtttccc cctgaccaga acattcactg ttctggtctt
    16561 ttcaccacga cgaccattat cgtgtttggc gactacggcg cgttattctt atatctttac
    16621 ttaattgcct tgcttccgat atctgttcgg tagaagagtc cttctatttt ttgttgggat
    16681 agttcttggt agatgctggc ttgggcttct ttgacggtat ctgctgtggt aacgagcata
    16741 taaactcgtc cgccgtttga gagcagtgct ctgctatttt ccgcaaactt agcccctgca
    16801 tagtaggtga tgacatcgcc ttctgtcttt gctggcaact caacgcccct ttcatagtct
    16861 agcgggtagc ccttggatgc gacaaccaca cccagagtca cacccttgtc cgtccacatg
    16921 atatttggct ccttgctatc caggatatct gtgatatttt gagcaaagtc agaggtcaag
    16981 cgaggcaaga taatctgagt ttctggatct ccgaaccgag cgttgaactc aatgactttc
    17041 ggtccatcag ctgtcaggat aagccctgcg taaagaactc ccagataagg gcgaccttct
    17101 ttaatcatcc cttctagaac tggcttgaca atggtgtcaa ccgctgtatc aactacactc
    17161 tgtggtaagt gtggaactgg cgcataggca cccataccac ccgtgttagg ccctttgtcg
    17221 ccatcgtagg cacgtttgtg gtcctgagcc gttggcatga tgtagaactt atcaccattg
    17281 acaaaggcaa agagtgaaaa ttcctctcct tcaaggaatt cctcaataac cacgcgcgca
    17341 cctgagtcac caaatttatt gtccaaaagc atctcatgag cggcttcgac cgcttgctca
    17401 accgtctcag caacgacgac acccttccca agcgccaagc catccgcctt gactacgata
    17461 ggcgcaccat gcttttcgat ataggccttg gcttcctcga aatctgaaaa tgtgccatag
    17521 gctgctgtcg aaacaccata tttgaccatg atttccttgg caaaatcctt ggaccactcc
    17581 agctccgctg cagccctagt cggaccaaag gccttaagcc cagcttggtt aaaatcatcc
    17641 acgataccag cagcaagggc atcatctgga ccgataaagg tccaagcaac atcattggtc
    17701 tttgcgaagt caatcaattt agaatgttcg gaaatagaga tatttaccaa ttccaaacca
    17761 tccagagtca tcccatcatt cccaggagct acaaagactt tttccacgtc ttttgattca
    17821 agtaactttt tagcaatcgc atgctcacga ccaccagaac cgacaacaag cagtttcatt
    17881 cctcaacctc ttttgcgaat tatttaccaa cattatatca aaaaagttcg ttttaatctt
    17941 gtttcagtta gcattttaag ccaaaaaagg aaagaaactg ttttcttccc ttttatcttc
    18001 ttaatgtcta aaatgtctca cacctgtaaa gaccatagtc aagccgtatt tattcgctgc
    18061 ttcgatggat tcttggtcac ggacagagcc accgggctgg atgatggcct taattcctgc
    18121 tttggcgatt tcttccacgt tatccgcaaa tgggaagaag gcatctgaag caaggaccgc
    18181 cccgtccaga cgatctttgg cttggtcaat ggcaaggcga acagaagcca cacggttggt
    18241 ttgacctgga ccaacaccaa gtgtcatgtg gtcgttggtc acgataatac catttgattt
    18301 gacgtacttg atagccttcc aagcgaactc aagagcagtc gcttctgtct cagttggctg
    18361 acgtttggtc accacttgcc agtcagctgg gctttccttg accacgtctt gattttgcac
    18421 gagaagtcca ccgactacac ctgtgtattc tgcttccact tcgctagcct cttgagcatt
    18481 aaatggcaag gcaaggatac gcaagttttt ctttttattg atcaaaatag ctagcgcttc
    18541 atccgtatag cttggtgcaa tgatgatttc gaggaaaacg ccgtgcatct tctcagctgt
    18601 cgcagcatcc acctcacggt tgaggacgac aatcccacca aagatagata ctgggtcaga
    18661 ctcataagcg tagtcccaag cagtctcgat gtcatcagct tgaccaattc cacatggatt
    18721 catgtgtttg agagccacaa cggttggact atctttgaag tcacggatga tacggatagc
    18781 agcatctgca tcacggatat tattaaatga caattctttc ccgttgagct gtttggctga
    18841 agcaatagag taatctgtag gcaaagcttt ctggtaaaag tccgcgtctt gttgaggatt
    18901 ctcaccgtaa cgcattggtt gcttgaggtc ataagtcaaa gtgagttttt caggcttgct
    18961 ttcacccact tgagctgtga agtattctgc aatcaaggcg tcataagccg ctgtgtgacg
    19021 aaatactttg gctgctaaac gttggcgagt ttcataagag gtttcgccgt ttgctgccaa
    19081 ttcgtccaaa accacagcgt agtcagcagg atctaccaca actgtaacac tggcatgatt
    19141 tttcgctgct gaacgaagca tagacggccc accaatatcg atattttcaa ctgcatcagc
    19201 ataagtcaca tctggtttaa ggatagtttc cttaaatggg taaaggttga ccaccacaag
    19261 gtcaatgagc tcaatcttgt tgtccttagc cgcttccaag tggctatcca agtcacgacg
    19321 agcgagaagc cctccgtgga tatttgggtg gagggtcttc acacgaccgt ccatcatttc
    19381 tgggaaacca gtcacatcat cgatagcaat ggtatccacc ccagcattat caagggcaac
    19441 cttagttcca cctgttgaga taatctccca accaagtttt ttgagttctt gggcaaattc
    19501 aacaatgccc actttgtctg agacgctgat taagacgcgt ttagtcatta tattctcctt
    19561 tttaatcatt agttaaacac caattaaatg cagtaacagt aaaacaagat aagcaaaacc
    19621 aaggctaagc atacctaaga tattgatcca ttttctagtc tgtgatttga acactcttat
    19681 aaaaatttga taaatcagta agcctacaca gacacctagc gtatttaaag tcaaatccgt
    19741 tatatctgtt atacctattg ctaaaatata ctgtaaacac tcaaacaata aactaatcaa
    19801 gaaacctgtc ccgactattc ttaaactaga taaattagtt tttatcaaag ggaaacaaac
    19861 acctaatgga ataaaggaaa tcagattaaa taacatttca gcaaaaacaa tttttccatc
    19921 gactattagt ggttctgaaa atggaatcca attgatatac cttggagcta agaaaaatgc
    19981 tataaattca ggatttgttt caaacttaaa taagattccc caagttaata acatcagata
    20041 gacataaaat acatatcgag ttgtttgttt agattctaac attacaaata cctccgtttg
    20101 aagccgtctt caacaaacac tgactccaat ttaaaatcaa agatatcata tgaatcatca
    20161 aaaagtcaat ctgtaaatag agccttcact acttccggat acaacctgta ctctgcttca
    20221 tgtatgcgag cttcaaatct gtcaatggta tcatcagcta gtcgtggcac acgaacctgt
    20281 ttgatgacct ggcctgtatc cacacccgaa tccacccagt gaatggtcac accagactga
    20341 cccacgccag cattccaagc atcctcaatc ccatgagctc ctggaaattc tggcaagtag
    20401 gctggatgaa tgttgacaat ccgaccttca taagccgaca ataaggttgg tccaacgatt
    20461 ttcatgtagc ctgctaggca aaccaagtca atctggtgtt cttccaagag ttcgacaagg
    20521 gctgcttcgt agtctgcctt gctctcaaac tccttgagtt caaaagcata ggacagaacg
    20581 ccgagctgct ttgcacgctc aagcacatag gcatcacgat ggtctgaaaa gacaaactcc
    20641 actggaaatt cttcggcaat cacctgaaaa tttgagccat tatcagaggc aaaaaccgct
    20701 atttttttca tttgataatg acactttcgt tttctttctt gacgatgcga ccaatttcat
    20761 agactgcttc atccaacaat tcttttacac gctctacatt ttcagggctg accgccaaca
    20821 taagtcccac acccatattg aagatttcaa acatttcttc gtgtttaatc tgaccatatt
    20881 tttcaagggc tttgaaaatt ggaagcactg gaactttgct ttcatcaatt tcagcagcta
    20941 ggtcatctgc aaacatacga gggacatttt cgataaagcc accacctgtg atgtgggcaa
    21001 tgccgttgac caactcttct ttgatgagcg gcaagacagc cttgacatag atacgagtcg
    21061 gctcaagtag aacttcctta agtttcttgc cttccaattc tggtaggact tcctcacctg
    21121 tgtaatccgc aaagacacga cgaaccaaag agtaaccatt tgagtgaatc ccacttgaag
    21181 caagtccgag aagaacatct ccctctacca cctttgaacc gtcaatgatt tgagattttt
    21241 cagccacacc gaccgcaaaa ccagccaagt catagtcgtc ttcgccgtac atgcccggca
    21301 tttcagccgt ttccccaccg atgagggcag caccagcctg cacacaacct tctgccacac
    21361 cagcaaccac ttgttctagc ttagctggtt cattcttccc tgtcgctacg tagtcgagaa
    21421 aatagagggg ttccgcacct gcagcaatga tgtcgttgac acacatggcc acacagtcct
    21481 gcccgatggt atcgtgcttg tcgtacttga tagccaacat gagcttggtt ccgacaccgt
    21541 cagtccctga aatcaagacg ggttctttaa ccccagtctt ggaaaggtca aacataccac
    21601 caaagccacc aagagctccc atgacacctg cacgctccgt acgggccacg tgctttttaa
    21661 tccgttcaac aacttcataa cccgcttcaa catccacacc cgactgggca tatgcatttt
    21721 tatttgtcat ttgttttttc cttttcttta atggagaatc tgtcgcctac ttgtaaaaac
    21781 tggtcttttc ttccaaactt ctacgatagt cttcttcgta gtcatagaga ggcgttgggt
    21841 agtcaccgtc aaagtaagcg acacagagac caccgttcgg cgcatctgtt tcgataccaa
    21901 tcgactcaat caagctatca attgaaagat aagtcagact gtccgcacca atgatttggc
    21961 gagtttcttc gaccgtatga ttggctgcaa tcagctcctg acgggtctgg atatcaatcc
    22021 cgtagaaaca tggatacgct agtgcaggac ttccaatggc aacgtgaacc tcagtcgcac
    22081 ccgcttcttt caagagctga acgatacgac gagaggttgt tccacgtaca atggaatcat
    22141 ccaccatgac cacacgtttg cctttgacaa cacccgaaac agcagacagt ttcatccgca
    22201 ctccttgctc ccgcaattct tgagtcggtt ggataaaagt tcgctgggtg tattggtttt
    22261 tgatcagacc catttcattt ggtaagcctg attcttccgc aaatcccata gccgcgctta
    22321 gggaagaatt gggcacacca actacaatat ctgcctcatg cttaaattct cgcgccaatt
    22381 gcgctcccat tctcttacgt gccgtatgga cattgacacc gtggatatta gaatcagggc
    22441 gggcaaagta gatatactcc atagaacaaa tcgccaactg ggtatcatct gtatagctgt
    22501 catactgaat gccctcgtca tcaatgatca caatctcacc tggcttcaaa tcacaaatcc
    22561 actcggcacc aatgacctca aaagcacagg tttcagagga aacaaccacc gctccgttgg
    22621 ccattttccc gatagaaagc ggacgaaagc cattagggtc aagagccgca atcaacttgt
    22681 cctcaaacag caagatatag gcaaaaccac ctttgacaag gctgagcgct tccttgattt
    22741 tgcccatcag gctaggatta tgactgcgac gaatgaggtg agccaagatt tcagagtccg
    22801 aagtcgcgct gaaaattgct cctctttgtt ccagttcttt cttgagagag gctgcattgg
    22861 tcagatttcc attatgagcc aaaccaaact gcatatcgtg aaaacggaag aggaagggtt
    22921 ggatgttatc aacagaagct tcgccagcag tcgcataacg cacatgccca atcgcaccag
    22981 ctcctgtcaa tttatccaaa ttagctggat ttctgaaaac ttctgataaa agccccatgt
    23041 cacgatggcg cttcagttgt ccttgatcat tggagaggat tcctgccccc tcctgaccac
    23101 ggtgttgaag actgtggagt ccaaaatagg tcaacttagc agcatctgga tgtccccaaa
    23161 taccgaaaac accacattct tcattaagag attttacttc gtatgtcatt ttttatacct
    23221 aattttcatt tgtaatcatc aagagctaga tttacatgac ttttacatta ctgatactat
    23281 ctattagaaa atctgtaagt cttattttcc agtgaaatgt ttaaccgctg atgcgaacag
    23341 gtgttggtct ttattgcctg ggatattttg gaaaagacca tcctcataac gttctgagtg
    23401 gcccatctta ccgatgattt gaccattctt gctggtaatt ccttcgatgg catggacaga
    23461 accattcgga ttgtacttag aatccatact tggtttaccg ttaaagtcaa cgtattggct
    23521 gaaaatttgt ccattgtcac ggagctctgc aaattcctca gccgtcacga caaacttccc
    23581 ttcaccgtgc gaaacaggaa tagcgtggat atcgcccact tgcacaccag ccaaccatgg
    23641 tgagttggta ttggcaatgc gagtttccac catcttggcc acgtgttggt tggcatcatt
    23701 gtagaagagg gttgggctag tactgttagc agcttcaaag tttccgtagg gtaggagacc
    23761 cgatttgact aaggcttgga atccattaca aataccgata atcaaaccac cacgggcgat
    23821 aaagctatca atagccacac acactttttc attaagcagg atattgacga taaacttagc
    23881 tgaaccatct ggttcatccg cagccgagaa tccaccagca aagaagagaa tattagtctt
    23941 gtcgatattg tcaaccatag tttcaactga cttgacaata gcttcttcat tcaaggtcac
    24001 gaatggcacc aaattgacct ctgcaccttc tttttcgaag gccttagctg aatcatattc
    24061 tgagttggtt cctggaaaga ctgggatgta aaccacaggt ttttcaacct tttctttggc
    24121 tttaatcaca acatctgatg ccacagctgg tacttcttct agttctttcg cttgggtaaa
    24181 ttctgttggg taaacttctt ccaatgtccc ttgaaatgca ctgtcaagct tgtgtccatc
    24241 tagcttcaca ccgttgacag tcagtgtaaa gtctgctttc gtttgtccaa ccttctctac
    24301 tccagcaatt tcttcaggag atgtgaagac aaagccgcct aattgagctg tcaaagctgt
    24361 tttaagttca ggcaaggtca cctctgcacc aatatagttt ccaaaggtag caagagccaa
    24421 actttcaact acaccaccgt atttgacagc tgatgcagat gtcactttat ggtcagcttg
    24481 gatggcttca aactgagtaa aatttttctt aatcaagtca aaatcaatct ctgcagagag
    24541 ggcttgacct gggatgtagt agatattttc cccaacagct ttaaattctg gagagagcac
    24601 cttacggcta tctgccgtcg tcaccccaaa ggcaaccaag gttggcggaa cggtcaattc
    24661 ttcaaaggta ccagacatgg agtccttacc accgatagat ggcaagccaa gctgaatttg
    24721 tgcttcaata gaacctagaa gagcagctac tggctgaccg aaacgctctg cttgtttatc
    24781 catacgctcg aaatactctt ggtaagagaa acgagccttg gaccagttgg caccagcagc
    24841 caccaaacga gcagttgctt cgataaccgc ataagcagca ccgtggtatg gagaccattc
    24901 agctacatat gggttgaaac cttgagcaat gaccgacgca gtatgagtca caccgtgttg
    24961 aactggcaat ttctgcacag atgcctcagt tggtgtgagt tggtaacgac caccaagtgg
    25021 gtgattaacc gttgagcgtc caacagagca gtcaaagata gtctgtaatc ctttttgact
    25081 tgcatggttg aggtcagata gaaccgtaag ggtatctgat tccagtgttt cagcagatgt
    25141 ttgacgctct tctgggagtt tgacatcctt gtccacaact ttggcatcga caaccacgcg
    25201 cacaccattg gtgtcaagga aacgacgctc caagtcaacg attgtctcac cattccagtg
    25261 catgacaaga tttggttttt cagttactgt cgccaccaca acagcatcaa tattttcttt
    25321 gttacattcg gcaacgaagg tatccacatc ttcaggacga accacgaccg ccatccgttc
    25381 ttgtgattca gagatggcaa tttctgtacc attcaagccc tggtatttaa gaggcacctt
    25441 gttgaggtcg atttcaagac cgtctgccaa ttcaccgata gccacacaga cgccgcctgc
    25501 cccaaagtca ttggacttct tgatcagacg agtgacattg ccattacgga agaggcgctg
    25561 aatcttgcgt tcttcgatgg catttccttt ttgaacctca gcaccagcag tctctacaga
    25621 ctcaactgtt tgaaccttag aagagcccgt cgcaccaccg acaccatcac gacctgtttt
    25681 gcctccgaga aggatgatca catcacctgc ttcaggtttt tcacggacaa cattgccctt
    25741 gggagccgca ccaacaacgg caccaagttc catacgttta gctacaaagc ctgggtggaa
    25801 gtattcacga acgtaggttg tggcaagccc aatctggtta ccatatgaag aataaccatg
    25861 agctgctgtt ttagaaatga cttgttgtgg caatttccca gcacgagttt ccgaaatcgg
    25921 tgctgtaata tcaccagcac ctgaaatacg catggcttgg taaacatagg aacggcctga
    25981 caacggatca cgaatagctc caccgataca ggtagccgct ccaccaaatg gctcaatttc
    26041 tgttggatgg ttgtgggttt catttttaaa catgaggagc caaggttcct tgacaccatc
    26101 aacatccact tcaatttcaa ctgagcaggc attgatttcg tcagagactt ccatatcatc
    26161 caatcgtcca ttagcacgct cataacgacc gaaaatagtc gccatatcca tcaaggtttg
    26221 tggtttttca gaccgaccta actcctcgcg catggcaata tacttgtcat aggttgactg
    26281 caattgcttt tgaaatttag aagctgaaaa gtcgatgtgt ttcaactctg tctcaaaagt
    26341 cgtatgacgg cagtggtcag accagtaagt gtccaaaacc ttgagttcag tctcagttgg
    26401 cacgcgcccg attgacttaa agtagtcttg gataaagagc aaatcatcca cttccatggc
    26461 catcccttgc tcggccttgt agcgagcaaa gtcttctgct gtatagcttt caaagaaagt
    26521 caattttgga atggtcttgt ctgactctga aaactcctgc ttggcaatcc ctgtcgtgat
    26581 atccttgaaa cgagaatcaa ctggattgag caggtagttt ttgacagctt ccaactcagt
    26641 cgcatcaata tctttattca ccaagtaaag ttgggctgtg ttgactgtca cgtcactcga
    26701 acttcccaac aaaagcaagg cttcctgtga cgaagctgca cgctggtcaa actgccctgg
    26761 cagactttca atggcaaaga aagcatagtt agcaagatcc gcctgcacag atacttcatc
    26821 taaaacatgg tcggttccct gctcagagaa aatgtgcttc tctgcaggtg caaacaagtc
    26881 ctcagccaag tcaaatacat catatacttg cacaatacga atacttttca agcttgacag
    26941 tcccaagttg tgctggagct ctctaaccaa actctctgac ttgacctgaa aatcagcctt
    27001 tttttcaaca aaaatacgtt tatccatcaa ttcttattcc tttatttcag ctcttgcaat
    27061 attcccaaac agccttgagg ttgttatttt aaaccctgca acttttccca gacaatttcg
    27121 taaacatctg ttagttcacc tagttctcta cagagtgaaa aggtctgggg gaccttttca
    27181 gcctgagtcc ttttagttga gagacgaagg ttttccgttg caaacagatt atttcaattc
    27241 ctgcaacttt tcccaaacaa tctcataaac gtcggttagt tctcccaatc ctctacggaa
    27301 aacatcctta tccatgtggt tgccatcagc gtcccacaag cggcagttat ctggtgaaaa
    27361 ttcgtctgcc aagataatct tgccatcctt gtcaaaaccg aactctagct taaagtcaat
    27421 caatttaagc ccaatctcag caaaccagac tttcaatagt tcattgatac gacgcgtttc
    27481 ttccttcaag taggcaatct gctggtcacc cgcaatctgt aggaatttca catgctcatc
    27541 attgataaat ggatcatcca aatcatcatt tttgtagtaa aattcgacaa tcggagtctc
    27601 caaggcgatt ccctcatcca caccaaaacg ttttgaaaag gaaccagcag tatagttgcg
    27661 gagcacgact tccaaaggaa taatcttaac ctttttattg agttgttccg tgtctgaaag
    27721 tttctccaca aagtgagtcg ccacaccagc cgcatttaat ttctcaaaaa taaaagatga
    27781 gatctgatta ttcaagactc ccttacctgc aatctgctcc ttcttgacac cgttgaaagc
    27841 agtcgcctgg tccttgtaag ttgaaataat aagattttca tcctcagttg tatagatatc
    27901 tttagctttt cccgaataga tcaattgttt tgacatttta aagttcgcct ttcgtattac
    27961 ttgagcacat tttaccacaa aaaaccaaaa aacacaagaa tttaaccgaa taaatagcat
    28021 atgtttttca aaaattgtaa agaaaaaact gcaagaagaa tctttctcac agtttaaaaa
    28081 ttatttaact ctaaaaacac gaacattact ctttgttcaa aaattgatcc aaataataac
    28141 gtagataact tttcttgccc gtaatcatct gcaagcggcc ttccaccccg tacctaagtt
    28201 tttcagcctg ctccgaagtt agattagtct ccgcctcgat tttaaagaaa ttccctttct
    28261 cagtcttagt agctgtcgca tcaatacttg taatagtaga atctagaaaa aattgattcc
    28321 cggcatcatg agtcgtagta tagcgaacag aatcaccgac cttgattctt gctacatctt
    28381 ttgaacttag ataggctgtg agtttggctt tcccttctct ttccaaagat ggataaagtt
    28441 gggctagtag ggcaccttct gcaaccatgc tagaatcact ggtctcagga ttaagatgaa
    28501 gcaccccatc ctcactcgcc gtaattttcc ccttgtctaa aagatttccc tgtaccttct
    28561 tacctgactc tgcctccaag attttctggg ctagaagggt caattcctga ccaacctttg
    28621 ccaagtgttg ggatttaagg gattccaatt gactgcttaa ccctgacgca taggcttgct
    28681 gggtacctga acctgcatac tggacacggt aagtagcaag actagattct aactgagaaa
    28741 tctgtgcttc aacctgtgca actgcctgaa ccttagtttg gggattttcc tcgccctgag
    28801 acttgtagga ctggtaaaga gagtaggcta gattctgacc ggccaaggaa gcacctgttt
    28861 caatagctga cttagctgtc tggtaatcgc gaattttagc ctctgtttga ctgatgaggt
    28921 tgccgatttc ggattgggtt tggctagctg ctgcattctg ggacgcgatg gtctcatttt
    28981 gttgcgatgt actagcccta agactgcctg cttgactgat gtagtcgcga aaggtggctt
    29041 ggtagccaaa cttatcctcc tctggaaagt ggttctcccc ttcttgcagg ctcttttgca
    29101 gatactccaa ttgctttttt tgatccttta gcatgtccaa ctgactggca taggactccg
    29161 cttggacacc ctctgcccct tcttggtatt gaaccaaaag atcccccttc ttaaccagct
    29221 tattttcttc caaatgattg acaagaatac gattgttgct agttgactgg atatttgcaa
    29281 ggatacgact gggttcgaca gtagctctag tggacaaact catctccttc tctgcaacag
    29341 ttgcaaagcc aagtaaaaac acgagcagaa gggccatggg tacaatcaca ctactggaaa
    29401 aattatggta acgacgatta taaaactccg cactttctaa aaattctggt ttcatcctct
    29461 cctctttcta gctattgacc aaatgggcgt aaaagccacc ctgtgcaagc aaatcagcat
    29521 gctttccttc ttcgacaatc ttgccctgat ccaagacaac taccttctct gtccgctcag
    29581 caatagtcaa gcggtgagca atgaaaatca aggtcttgtc caaagctatg agattatcga
    29641 caatccgctt ctctgtcaaa atatccaaac tgctagtcgc ctcatccaaa atcaagaccg
    29701 gcgcatctgt caagagagca cgcgccaaag cgattctctg acgttgacca cctgaaatcc
    29761 ctgccccatc cgaagtcaat tctgtctgat aattcagtgg catgcgctcg atatcctctc
    29821 gaatctctgc caattcgacc gcccgtaaga tatcttcctg tgtcgtcccc tccttggctc
    29881 ccaaaagaag attctccaaa atcgttccgt taaagacata gggctgttga ggcagatagt
    29941 tgatgtactg gcgcagggct tttttatcaa tctgattgag attgacacta cccagactaa
    30001 tctccccttg acttgggtcg taaaaattaa ccatcatctt ggccaaagtc gtcttacctg
    30061 accctgaaat ccccacaaaa gccaccttag acccttgggg aacggttaaa ttgatatccg
    30121 acaagacgtc tcgaccatag ccatacttgt aatgaacctg cttgaaggtc atatctccct
    30181 tcatcaagct caaatcctca actgttttct tctcctcaaa ctcagaagct actagataca
    30241 cttcatttag acggttattg gcaacctgcg ctgtctgaag cttggtttgc agattgatga
    30301 tattttccaa aggattggta aagtaaacca gcaaggtatt ataggtaatc aactgcccca
    30361 aactcatctt gccatccatg accagaacag cccccatcca gagaatgccg acattaagca
    30421 agagatgggc aacctttttc agagcctttt gctgactctc tgctcgacta taggtaaagg
    30481 atttcttcag ataatccaca aattccttgt caattttttg gtaacgctga ctttcactgg
    30541 tcaaggactt gatagtctca ataccgttga tgtcctcaat gatagaagaa aacagaaccg
    30601 cattggcttc catggtatcc cgattcatct tttcaaacgg cttcataaag gcaaagataa
    30661 tcactgtgta gataggaagc gccaataaag tcatgaaaaa gagattggta ttttgtgaaa
    30721 atagaacaag ggaaataatg acaaccgttg acacatctag gaaaatcgaa agaatggtcg
    30781 aagccagcgc atcgatgata ctgttagcat ctgtaaaacg agacacgatc tcccctgtcc
    30841 tgcgtgtcgc aaagaaggac atagggaggt gaaaaacatg cttgatatag gacaaaatca
    30901 cgtcaatcga caagcgttgc cccaaaacaa gcaagagata ctcctgagcg taagacaaga
    30961 tttgctggag gatgtagacg atgactagcc caatagaaat aatccctagt gtcgaacgca
    31021 tctgatctgg cacataggta tcaatgatag actgcagata ataagaaccc acaatgttaa
    31081 tcccggttac caagagtgtt gccaaaacga tattggcaat caagccacgc tgcttcacta
    31141 atatagggat aaaagagagc agaccatttt tttgttcctt ataaggctta tagtctggac
    31201 taggtgccat aaaaagagtc actcctgtcc attcttcctc aaaacgctca cgtggcagtt
    31261 tagtcaactt caccccggga tctggatcgg caatatgaat gctatcctta tcctgcccag
    31321 tcaccacata gtagtggagc aatttccctt ccttaagcac atgggcaaca aaaggaaaag
    31381 tcaaatccgg caagtcaaaa agcgtcatat ccgccttaat ggctcgcgtc tcaaaaccaa
    31441 tctcctctgc caccttgacc aagcccaaag ccgtcgtccc atccatggtc gtcttagcca
    31501 attctcgcaa gtgagccaaa aaataataac taccatagta gccaaaaacc atggctaatg
    31561 aagctacacc gcagtccatc tgatccactt gcggacgata gtgacgtttc ccaaatttca
    31621 tattcatctc cttttcccta atactcaatg aaaatcaaag agcaaactag gaaactagcc
    31681 gcaggctgct caaaacactg ttttgaggtt gtagatagga ctgacgaagt cagtcacata
    31741 tatacggcaa ggcgacgttg acgtggtttg aatttgattt tcgaagagta taaactcatc
    31801 tgataacaac tatcttaccc caatcactaa acaaaaactg gacttccttc ccaaatgagc
    31861 ctatctccct cccaactgca ctttttggat aaaaaaatag gcagaacaaa cgttctacct
    31921 agaaaatata agaattacaa gttaacaaaa ccgaaatgat ttcatatcat tattaagtaa
    31981 agaaaaaaat tttagtattt ctaaaaacta tttataatag acattatagc attaaataaa
    32041 aatggtacag aaaacactac tgtcaatctt aaatttttaa atctcgcata gtttgttatc
    32101 ccaattagta atactgtcaa tacgctgaaa taggcaaact ttatatccga tggattaaat
    32161 aaataacaaa gtaaaatgct aaaacttaag gttatatttt tagataaaag aatatctcca
    32221 aagttcctct tattcttatc aaaaaataat gtaatcagaa agagagaaaa tccatattca
    32281 ataagagttg ctataaatgt gaaaacaaca gaaatcactg tcaatattgt ttctatttta
    32341 attgtaaaaa gattagatag ttcagataat ttatcaattt gttcatctaa aattcccgac
    32401 ttcattagta aatcaataaa caaatataaa agaaaaagat aaataatcag attcattaat
    32461 ttgtataaac tattatttgt ttgaaatttc ataaacccgt ccttcctcta ttaaaatcct
    32521 ttgagatttg ctaatcaatt cttgattcaa taaattatga gatacatata taatagtaga
    32581 gctttctttc atggaaatta agcgtttagc aatcatatca atacttcttg catccactgt
    32641 tgataaagtc tcatcaataa aaatataatc ccaattttta gcaaaaatta aggataagcc
    32701 taatttgaat tttgttccag tagatgctgt catatagtta tctccgattt tattatcaaa
    32761 aaaagtatta atttgttctt tatcctcaaa tgatagatgg atttgaaaag aatcacacaa
    32821 caactgcaaa ttttcttcta tagtaaatgg aacaacccca agctgattgg tatcaaggta
    32881 tagtacatct ttggagacac aattctttaa accactatca aaagtctcta gcccagctaa
    32941 aagttgtaga agggtgctct ttcctgaacc attctctcct tcaactctgt aaattccctt
    33001 atcaatctct agtgatatat ttttcaatat acatttatca taacttttag attcattttc
    33061 aattttcata atttaattcc ctctatcaac gctgctaaaa ttaataaaag ataagaaata
    33121 atataccatt ttaaattact ttttatataa ataagtatat ttttaattcc cctatccttc
    33181 aataatcggt ataaaagata ctgactcata ccttgatacc aaataaaatt cggtatttca
    33241 ataagagcat gaggtaatat tccttttatt gtagctacta ttccaatcat ctgaccagat
    33301 atacccaatt gtattcctaa agatagcaaa tcaaaaagtt gcaataaggg cgaaatcgga
    33361 aaacagaata gatatagcaa aaaatttgta gaatttgcct gtaaaactgt caatgtaaat
    33421 tgtaattcca gtttcggagg tatagtagca aaagtctcat tttttaatat aaagcttaaa
    33481 agtaaaccta gtaaaaaaca gactatacaa aataacacat agtaaatcag aaaaccactt
    33541 tttctcatct aatgccccct actaaaatta caaatattat cagaaaacaa tataaaacca
    33601 gaaaactcca tctcaataaa ctaactgtac ctttaattaa aaatagagct ttcttataat
    33661 agacataggc tataaaataa ttgaatggaa tcaataacaa attcaacaaa atacttttta
    33721 tatcattact ataacttgtc accggaatca aacataacaa caatgaaaat tgtaagaaag
    33781 agattaaatg cgtcaacatc attagttgtg cattcttaaa aaagaaattc attttagaat
    33841 gattaagagc agataattga agtaaagcta gatctacccc aattgaggat ttatgattcc
    33901 ctattattgc ctccattaat gtaatatata ttgaggtata aagaaataat attggtattt
    33961 ttgtgtcatc aattgataac atcgtcatca tataccaaaa tagataggaa agaagaatac
    34021 taatcaaaat aaaagaaaaa gttaaccctt tatttaacca acaaaaacga agcaatataa
    34081 atagactgct acgaaatctt ttttgactca ttcgactgct tttaaaatag aaattactcg
    34141 catgattatc taatatcccc atgactaaaa taaaataatt gagtagtatg acataaataa
    34201 caacttgtcc ttgttctata gacaatagtc ctatagataa aaataagaac aatttactta
    34261 taattgaaaa caaactaggt agaattaaag aaataatttg aatagctatc aaacaaagag
    34321 taatggataa ataaaaatat ccaataatat ctagaaaata caaaataaat aaataaataa
    34381 atgaatgatt gtaaaatttg gaaagaataa tatttcttga caatggcaag aagatagaga
    34441 aaaatatagt ttttccttat atagaaagta tttatttttt tactttggat aggcagtttc
    34501 atattataac gattcaaagt agcgtaatct actaccaaaa aaagtaaaaa taatttccct
    34561 tgaaaaggaa gatagctttt aaaatagatt gacaaactta tgataacaaa aaacaaaagg
    34621 gttatcccaa taaaattaag ataacctaaa atactttcac attctttttt agaaagtatt
    34681 ttcatctagt tctaccatag agctgcttta gcagcacctt tctttttcaa tatataaaga
    34741 actgttgctg caatacccga accaatagaa cctactcctg tgattgcacc tacaattgaa
    34801 attactgctg taactgtact ataagcacta atcaaattga ctacagtagc agcagctttt
    34861 gtcgaaattc ctaatgtccc agccaacata ggaaaagaaa caacacctaa gcttaaccaa
    34921 ctaatgactg ctaacattgc tgaaacaata agaaatttat tatgaaattc cattctttta
    34981 gatttcattt tagtgtactc cttttgtata ttatgtatgt tttattgaga gttaattcgc
    35041 acatgttgta ttcctaactc tcttcaaatg ttcgtctata ttttatacta cttttattaa
    35101 catatctata ataaataaat tactactaca ttttcctaga ttatcaaatt acttttatat
    35161 cactaagact caataaaaga taatgtctat ttaactttta tacgattact acctcctttt
    35221 tagtttacac ttcctacatc ataaataaac atactcaacc ctcacaatct ccaaataact
    35281 cttctatatc attgaaaatt gagtttcatc ctctatacta atgtaggaaa cctattaaaa
    35341 cattccttta atccaatata ggaatacctt atgccattaa tctctacctg atattataga
    35401 tagaaccaga ctcctatact taaaaggaca aacaacgttc caaccataat aaacttcctt
    35461 tctttttgga atcgttttct ttatgagttt agtataacaa aaacatgaaa aaaacaacat
    35521 gacttagaag tcaggttgtt gggaaatcta tttgtttttc tgctaaaatt ttctgaacta
    35581 atacctgatc atctagcaat tctgctagag aaatcgcctt ttcatagaaa ctttctgcct
    35641 ctgccacatt cttatctaca aataaagcat atttcgcctt taacaaaaat agatgaggtc
    35701 ggtaaaaaac atgtcttgtt ttagcaataa ttttctcaaa tgtttgaata tatatcagac
    35761 tatcttctgt ctgaatttgg ataaataggc tcagaagaac tttttccatc tgaactaggc
    35821 tatccttatc ttcatattct gaacatagca atactttttg agctaactcc tcaaaatgtt
    35881 ctttatcttc taatcccata gcacaacaaa agaaatacaa ttcaataatc aacaaatcat
    35941 ttacagaaaa atatttcttt tttaataact gctggaaata ttcttccact aaccctaaac
    36001 cgtaggtcac atctgaacta ccataaatat caaaacgagc ttgtgtcaca tccacaatta
    36061 actgctcttc ctcaggcaaa ttctcataat agttttcata tatttcctca agtatagctt
    36121 cttttcgttc gattcttccc ttatcagcgt aggtttgaga atgaatcagc tcatctttga
    36181 gttttaggaa tccttttgga atctctataa ccttaacatc cacaatattc tgtaatgata
    36241 ctccaagttt atccgcaatc aataataatt taggaagtgt tgctaaagct tgcccatttt
    36301 caatacgtgc tagctgacga atcgtcaact ctgattcatc accacaaata tctatctgag
    36361 tttttccaca agatcgccta atagttttga ttttataacc aatttcacgt ttcaactcat
    36421 ccatagtaat actccttaag ttgattacaa agatttcttt ttcttcctaa ttcttttgtc
    36481 aatcatatat aaaacgataa gcgaaaacag cggtagaaca atataactct tttcactcat
    36541 tatcagctga aatcccaggg ttgctagtat cttaaagatg aaaatattca tcaaaaatag
    36601 aaaaacaaat actaaaaaat attttaaaac cttcttcatt tcttttcttc aactttccta
    36661 atttctacac ctattttatc gaaaatatat ataaaactcc aaataaacac ttcaactgca
    36721 ctttttttgg caaaaaatag acagaacaaa catcctacct actaaaaata tgatatgaaa
    36781 ggaaaatgat tttttactga caccctaggc aagcttggga caaataaatc attgatagca
    36841 acatttacga catcctattt aaagttcctt caatttctaa tgtccccgct atttctaagc
    36901 tacctctggt atgatctatt cctagtcaga atagataaca ccgttctaaa ttacgattca
    36961 tagttactcc ttttttgact cgttactata agactcctct ttacatgcgc aaaataattt
    37021 tgattcagat tcatcattta tagttttgat tattttttaa cagatttttc tgttttcttc
    37081 tccgaagact ttaaaaattt ttttctaatt aaatcatcca tataaggacc aaatatacca
    37141 actactaaac caataataaa acttttaaaa tccataatta ccaccaacat gtcgctgcat
    37201 aggccacacc tccaagtata gctcctcccg cagcaccagt tgctgcacct tgccatgttc
    37261 ttgttttaat tcctagctga agacctcgtg ctgctcctcc tccaacacct gctttggcaa
    37321 aatctcccca attgcatccg ccaccttcaa cgcaagcaag catctcagta tccataattt
    37381 caaattgtga catctttttt gtattcataa cgaatacctc ttttttattt ttaatatttg
    37441 tcttgttaca aacttgacaa gtttagtata acagtatcta ttaatttttt tcatccaaat
    37501 cttgaattgg catcgaaacg tcttgaatta gcttttttgt ttcaaaatca tctctatttt
    37561 taaaaaagat gttttctaat cactttttta ctattagact tcctgcaaaa ctagaatcct
    37621 agttcatgat tgataatacc agcaatcaaa ttcattcgta atccgaagcg tttacgatga
    37681 tttcgatagg ttgttgaaaa cattttaaac gtttttactt tggcaaagat gttctcaacc
    37741 ttgcttctct ccttagatag cgcatggtta caggctttat cttcaactgt tagcggcttg
    37801 agtttgctgg atttacgtgg agtttgtgct tgaggatata tcttcatgag cccttgataa
    37861 ccactgtcag ccaagatttt accagcttgt ccgatatttc tcatttctaa aaaccatcta
    37921 cttccgttga cttggaactc cgattgctat tttccttgaa tgattttaac cacatctcct
    37981 acactttgga gttggtcaat ttcctcatcg ctgatttcga tactaaattc atcttccaga
    38041 gtcaagataa actccatcaa gtcaacagaa tccgcatcca aatcgtcttt cagactcaag
    38101 gattctgtca cgacaaagtc ctctccctgt cgctcttgga taatggtcac aatacggtca
    38161 aaaatttctt tttctgtcat ctcttttatt ctcctgaaaa ttcacgcgca gtctgggcaa
    38221 ccacgtctgt ttctagcatg gtacgaatct gacgaatcgt actataaaca gccttggcat
    38281 cgcttgagcc atgagtcttg acaacaggtg ccttaacacc aaacaatacc gctccaccaa
    38341 catctgaata attgagctgt tttttcaaac cactgaggct gtccttgaga aggagggcac
    38401 ctagtttcgc tcgaagacca ccacctgtaa tagctgtctt gagcaagccc acgattccca
    38461 tagctgtccc ttcgatggat ttgagcacag cgtttcccgt gaaaccatct gccacaacaa
    38521 catctgcaac gccattcatc aaatcacgcg cttccacgtt tccgataaag ttcaaacttt
    38581 catcagccgc cagtaattca taagtttcct tacgaagcgg gtcgcccttg ctactctctg
    38641 ttccgttgtt gagcaaacca acgcgtggtt gcgcaatgcc acggacattt ttagcataga
    38701 aggaacctag aaccgcatat tgatggaggt gctgggctgt attttctgca ttggcaccaa
    38761 ggtctagcat gtcaaaacct tttccatcaa cggtaggcaa ggtagacatg agtccaggac
    38821 ggtcgatatt cttgatacga cccacgatga agaatcctgc tgccaacaag gcacctgtat
    38881 tcccagccga aaggacagcg tctgcttcac catctttgac agccttggct gccaatacca
    38941 tactggcatt tttcttattc ctaatagctc tcgtaggttc atcatccgaa tcaatcttct
    39001 catccgtatg gataatgctg acgcgctctg tcgctgtcag atattgcttg attttagctt
    39061 catctccgta aagttgaacc tcgatatctg aaaagtcaga tagggcttga ttgacaccct
    39121 caacaatggc ctgaggtgcg taatcgcccc ccatggcatc tactgcgatt tttttcattt
    39181 cttttcctct tttagtaatt gtccccagtc tgctagggaa tcaataaatt tctttgattt
    39241 taggtgaatc ccaacgtact cttcatataa ttgatccata aattggcgta gctcttgctt
    39301 gattccaggc ttgagcgaaa tggtctccaa agtctcaaaa tcaatagctt gaaattgatt
    39361 gagcagatag gggatattgg gattgagatg acaacgtctc ttatcctcat gataatgctc
    39421 tggacagagg caggctccat atttgaaaga aaagtcaaaa gcctgaccaa cccgatggca
    39481 gaagacacac tcattaaaat tgaggctgat tccaaatcga gtcaaaattt gaatttcaaa
    39541 aatattggtc aaaacctgat aatccaagcc tgcttccatc aactccaaag tcttttgcaa
    39601 aaaagcaaac aagggagcat cctgctgatt gtcctgcaaa ctagcatctg caagagctgc
    39661 cacataggtc gcataggcca tgacaaagag gtcactatta atcttgggaa aagtcatgac
    39721 ctcatgatag tcttcgatgt aactgagtcc gtcatcattg attcgcaaga gaaatcgtgc
    39781 cagcaccaag ggctgaataa caggcgccag cttagactga ccagcgtgtt tgacaaaaaa
    39841 catgcgtttg ccaacctgct ctgtaaaaat tttgacgagc ttgtcatcct cacgaaaatt
    39901 gcgattgtaa agcaccaagc cttgactcgt gatagactga atcatgcttc tctcatgtac
    39961 tcctcaagtc gtttcatggc ttctttgata gtctccatgc tggctgcata agataggcgg
    40021 acgtagcctt ccccgtaacg tccaaaggct gcaccaggga taaaggcaac ggccttcttc
    40081 tgagcaaaat ccttcagaaa agcaaaggag tcttgattgt agcccgctgg aattttagca
    40141 aaaatataga aggcaccgtc tggtttgata atctcaaaac caagagcagt cattttttcg
    40201 atgatatagt cccgacgctg gatatattcc ttcttcatgg gctccgcatc atttttacca
    40261 gccgtcaagg cttctaccgc agcatgttgc gccatggtat ttgcggcagt gaccaagtat
    40321 tggtgactct tgattaactg ggctgtgaag gccgcaggag cgaaaatcag ccccaaacgc
    40381 caacctgtca tggcatgcga tttagacaaa ccattgataa taatagcctg gtctctcaac
    40441 atcgttccta gagacacatg ggcttcgcct gtgtaggtca attctgagta aacctcatca
    40501 cagacaacaa aaatttcgta cttgcgtaaa acagctgcca aggcctctaa ctgctctcga
    40561 ctgtaggtaa ttcctgtcgg attggctgga tagttgagaa taaccgcctt gagcttatca
    40621 ccctgctcca aaatggcctt ctccaacatc tcaggagtca agacaaaacc attttcagtc
    40681 gtatcaatct caacaatttc tgccccaact aagttaacaa tcggttcata gcctggataa
    40741 gcaggagctg gcaaaagtac cttgtctccc tcttccaaaa tagccgtcaa agtcgcagat
    40801 aaagcctctg tcgccccaat tgtaaccaag atttcatt
//
LOCUS       DAVDHZ010000014        39353 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000014 DAVDHZ010000000
VERSION     DAVDHZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.014"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(395..1084)
                     /gene="rplA"
                     /locus_tag="VUR46_000920"
     CDS             complement(395..1084)
                     /gene="rplA"
                     /locus_tag="VUR46_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET5456372.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1292..1717)
                     /gene="rplK"
                     /locus_tag="VUR46_000921"
     CDS             complement(1292..1717)
                     /gene="rplK"
                     /locus_tag="VUR46_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET5456373.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2026..2742)
                     /locus_tag="VUR46_000922"
     CDS             complement(2026..2742)
                     /locus_tag="VUR46_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET5456374.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2745..3215)
                     /locus_tag="VUR46_000923"
     CDS             complement(2745..3215)
                     /locus_tag="VUR46_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET5456375.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(3217..4254)
                     /locus_tag="VUR46_000924"
     CDS             complement(3217..4254)
                     /locus_tag="VUR46_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET5456376.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDCIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(4352..5677)
                     /gene="brnQ"
                     /locus_tag="VUR46_000925"
     CDS             complement(4352..5677)
                     /gene="brnQ"
                     /locus_tag="VUR46_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET5456377.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5848..5940)
                     /locus_tag="VUR46_000926"
     CDS             complement(5848..5940)
                     /locus_tag="VUR46_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5456378.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5983..6135)
                     /locus_tag="VUR46_000927"
     CDS             complement(5983..6135)
                     /locus_tag="VUR46_000927"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5456379.1"
                     /translation="MKEIAFDVFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LTDSYD"
     gene            complement(6295..6873)
                     /locus_tag="VUR46_000928"
     CDS             complement(6295..6873)
                     /locus_tag="VUR46_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET5456380.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     DFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6927..8327)
                     /gene="pepV"
                     /locus_tag="VUR46_000929"
     CDS             complement(6927..8327)
                     /gene="pepV"
                     /locus_tag="VUR46_000929"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET5456381.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGPAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8340..8945)
                     /locus_tag="VUR46_000930"
     CDS             complement(8340..8945)
                     /locus_tag="VUR46_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET5456382.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9116..9916
                     /locus_tag="VUR46_000931"
     CDS             9116..9916
                     /locus_tag="VUR46_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5456383.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10100..10933)
                     /locus_tag="VUR46_000932"
                     /pseudo
     CDS             complement(10100..10933)
                     /locus_tag="VUR46_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
     gene            complement(10923..12770)
                     /gene="uvrC"
                     /locus_tag="VUR46_000933"
     CDS             complement(10923..12770)
                     /gene="uvrC"
                     /locus_tag="VUR46_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET5456384.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERAVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12810..13511)
                     /locus_tag="VUR46_000934"
     CDS             complement(12810..13511)
                     /locus_tag="VUR46_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET5456385.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13590..14822)
                     /gene="murN"
                     /locus_tag="VUR46_000935"
     CDS             complement(13590..14822)
                     /gene="murN"
                     /locus_tag="VUR46_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET5456386.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14827..16047)
                     /gene="murM"
                     /locus_tag="VUR46_000936"
     CDS             complement(14827..16047)
                     /gene="murM"
                     /locus_tag="VUR46_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET5456387.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16159..16938)
                     /locus_tag="VUR46_000937"
     CDS             complement(16159..16938)
                     /locus_tag="VUR46_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET5456388.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17007..18668)
                     /locus_tag="VUR46_000938"
     CDS             complement(17007..18668)
                     /locus_tag="VUR46_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET5456389.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAESKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18843..21065)
                     /gene="recJ"
                     /locus_tag="VUR46_000939"
     CDS             complement(18843..21065)
                     /gene="recJ"
                     /locus_tag="VUR46_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET5456390.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21342..22100
                     /locus_tag="VUR46_000940"
     CDS             21342..22100
                     /locus_tag="VUR46_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5456391.1"
                     /translation="MALVEFKNVEKYYGDYHALRDINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LSPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDMTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22140..22904
                     /locus_tag="VUR46_000941"
     CDS             22140..22904
                     /locus_tag="VUR46_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET5456392.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDTLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22917..23594
                     /locus_tag="VUR46_000942"
     CDS             22917..23594
                     /locus_tag="VUR46_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5456393.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPFYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23604..24263
                     /locus_tag="VUR46_000943"
     CDS             23604..24263
                     /locus_tag="VUR46_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5456394.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKIKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGCYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24497..25687
                     /locus_tag="VUR46_000944"
     CDS             24497..25687
                     /locus_tag="VUR46_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET5456395.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKRVHFYYSFRGEENAVYLDLLRDYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26008..26889)
                     /locus_tag="VUR46_000945"
     CDS             complement(26008..26889)
                     /locus_tag="VUR46_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET5456396.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27030..28358)
                     /gene="vncS"
                     /locus_tag="VUR46_000946"
     CDS             complement(27030..28358)
                     /gene="vncS"
                     /locus_tag="VUR46_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET5456397.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVAQD"
     gene            complement(28355..29011)
                     /gene="vncR"
                     /locus_tag="VUR46_000947"
     CDS             complement(28355..29011)
                     /gene="vncR"
                     /locus_tag="VUR46_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET5456398.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29060..29143)
                     /gene="pep27"
                     /locus_tag="VUR46_000948"
     CDS             complement(29060..29143)
                     /gene="pep27"
                     /locus_tag="VUR46_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET5456399.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(29323..30702)
                     /gene="vex3"
                     /locus_tag="VUR46_000949"
     CDS             complement(29323..30702)
                     /gene="vex3"
                     /locus_tag="VUR46_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET5456400.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30754..31401)
                     /gene="vex2"
                     /locus_tag="VUR46_000950"
     CDS             complement(30754..31401)
                     /gene="vex2"
                     /locus_tag="VUR46_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET5456401.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31414..32691)
                     /locus_tag="VUR46_000951"
     CDS             complement(31414..32691)
                     /locus_tag="VUR46_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456402.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33048..33218)
                     /locus_tag="VUR46_000952"
                     /pseudo
     CDS             complement(33048..33218)
                     /locus_tag="VUR46_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(33361..33507)
                     /locus_tag="VUR46_000953"
     CDS             complement(33361..33507)
                     /locus_tag="VUR46_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456403.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            complement(33504..33959)
                     /locus_tag="VUR46_000954"
     CDS             complement(33504..33959)
                     /locus_tag="VUR46_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456404.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTIYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSEITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            complement(34096..34980)
                     /locus_tag="VUR46_000955"
     CDS             complement(34096..34980)
                     /locus_tag="VUR46_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET5456405.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(34984..35370)
                     /locus_tag="VUR46_000956"
     CDS             complement(34984..35370)
                     /locus_tag="VUR46_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET5456406.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(35363..36706)
                     /locus_tag="VUR46_000957"
     CDS             complement(35363..36706)
                     /locus_tag="VUR46_000957"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET5456407.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(36793..37677)
                     /locus_tag="VUR46_000958"
     CDS             complement(36793..37677)
                     /locus_tag="VUR46_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456408.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYQLAKLSNLEVLLADSSY
                     QEQISQLKFQAFSGEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(37689..38306)
                     /gene="cysE"
                     /locus_tag="VUR46_000959"
     CDS             complement(37689..38306)
                     /gene="cysE"
                     /locus_tag="VUR46_000959"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET5456409.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHSSSGL"
     gene            complement(38322..>39353)
                     /locus_tag="VUR46_000960"
     CDS             complement(38322..>39353)
                     /locus_tag="VUR46_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET5456410.1"
                     /translation="RYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESN
                     GSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDF
                     KVAGTRDGITALQMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPT
                     APKIDTIKIDVDKIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAK
                     EIIAGLVREAKVDEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVE
                     IGDEVDVKVIKIDEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKE
                     FTETPKDSE"
BASE COUNT        11097 a         9052 c         7354 g        11850 t
ORIGIN      
        1 ccatacgcac ggcaaggcga cgttgacgtg gtttgaagag attttcgaag agtattagaa
       61 agctcgatgg actattccag attcattcca ctagatttcg aaatcgagta ggggataatc
      121 tctagcccct ctcacaccac cgtacgtgcc gttcggcata cggcggttca actaactgtt
      181 aacgcatgtc gttcaaggta ataatccaaa cacgaaacca gtccacgttt ttcaaggact
      241 ggttttgata tagcacgttt aagtaccgac ttctgagcta ctatagtaga ttgaaactag
      301 aatagtacac atctactata caacatgccc gtcgtacatc aaaaaaagtt gagacatagc
      361 gtcttcaact tttttacatt actttaacta ctgattaaag tgagtttacg tcaactttga
      421 taccaacacc ttgagtagtt gtgatagtca agtttgttac gtaagttcct ttagctgtag
      481 ctggttttgc tttttggatt gtttcgttga aagctttaaa gttttcaacc aatttttcag
      541 cttcaaatga tactttaccg atgattgctt gaacgttacc tgcacggtca gcacggtaag
      601 tgattttacc acctttagac tcttcaactg ctttagcaac atccattgtt acagtaccag
      661 ttttagggtt tggcatcaag ttacgtggtc caaggacacg tccaagacgt ccaacaagag
      721 ccatcatatc aggtgtagcg ataactacgt cgaagtccaa ccaaccgtcg ttgattttag
      781 caacaaggtc atcttcacca acaaagtctg caccagcagc ttttgcttct tcagcttttg
      841 caccacgtgc gaaaacaaga acacgtgaag ttttaccagt accgtttggc aataccattg
      901 ctccacggat ttgttggtca gcttttttaa cgtcgatgtt caagttgtaa gcaacttcta
      961 cagttgcatc aaattttgca aagttagttt cttttgcaag tgctacagct tcttctacac
     1021 tgtatgcttt tgtgctgtcg attttctcaa gagcagcacg aagttgtttg ctttttttag
     1081 ccattttcta ttctccttgt aagtggttca atcgattttc atctcccacg tcacttctcg
     1141 aaatgatgaa gtcttgcggg ttttcagtct actatttttc tcttcctacg gccttaagct
     1201 cccttgctgt acccaagtac aagcctcagt cacttgccta gtatgaaaag caactaatag
     1261 actgctgtga gattttctac tgtgttattg attagtcaac aacagtgaat cccatagaac
     1321 gagcagtacc ttcgatcata cgcattgcag actctacgtt tgctgcgttc aaatctggca
     1381 tcttagtttc tgcaatttct tgtacttgtg cacgagtaac tgtagcaact ttagttttat
     1441 taggtgtacc tgatcctttt tcaacacctg cagctttttt caaaagaaca gcagctggtg
     1501 gtgttttcgt aacgaaagta aatgatttat cttcgtaaac tgagataaca actggaatga
     1561 tcataccagc ttggtcagct gtacgagcgt tgaactcttt tgtgaatccc atgatgttga
     1621 taccagcttg accaagagca ggtccaaccg gtggagctgg tgtagcttta ccagcaggga
     1681 tttgcaattt tacaagtttt tcgacttttt tagccatttt taaatcctcc tttgtggttt
     1741 tggcggtaat tagagatttt tacctcccac aagtatgttt ttcacatacc catccattat
     1801 acactattta tctggaattg caagagaaaa gtttattttt tgtactcaat gaaaatcaaa
     1861 gagcaaacta ggaagctagc cgcaggctgc tcaaagtaca gctttgaggt tgcagataaa
     1921 actgacgaag tcagctcaaa acactgtttt gaggttgtga atagaaccga cgcagtcagt
     1981 aggtaaggcg acgctgacgt ggtttgaaga gattttcgaa gagtattaat cgacgtagtc
     2041 tccgccttca aagccatagt attcttccaa actgagacca cttgcagcaa tttctttagc
     2101 ttcttttcct acataacgca ggtgccattc ttcagccata tagcctgttt ccttttcctt
     2161 gcctttgaga taacggacaa caaagccata atcagctgca tgatccaaga gccattgggc
     2221 tgctttttct tctgtcacca aatcaccatc agtcccaatc acatcaaagg ccaagcctgt
     2281 ctggtgttcg ctatagccag gacgggcaga gtaacggtca gctgctgcct ttccatcttg
     2341 gttgacataa tcttgataga gcttggtctg agtttcataa cttctaaaac cactgtaatg
     2401 atcactaata gggaaacctg cctcttgcat cgctttgatg agtttgacca actctgcctt
     2461 ggctgttgga ttttcccctg gattatagtc tttagacaat ggatagtgtt tgttggctac
     2521 gatgatttca tcgtatttcc cttgaatgct gtagtaatca cctttattga ccacttctgc
     2581 tttcttctgg gcagctcctt gagacttact accgactgtt ccatcagctt tggctgtctg
     2641 ttctgtctta gtttctccat cttcattttt tgttttttct tgtgaacaag ctgctagact
     2701 caaggctagc aaagctgtca agactaggta tcttttcttc atttctactc ctttatttct
     2761 aatagtttat ctacttctga cgataaacgt ttgactaatc ttttaatctc atccggtttt
     2821 gcttggcagg tttctgctgt catttcttca aagggaaccc accagactgg tccacgaccc
     2881 ttgagaccat gaccattcat atcacctgtc cgtcgtggaa acagatgcca atgaagatga
     2941 gcatcgccat ttcctagcag ttcgatattc attttctcag cagcaaaggc cttggcaact
     3001 gcctcttgga ctaaactcat ttcttctaga aaacggagtc ttgtctcctt tttcaaatgg
     3061 tgcaattcgc tgacatgctc cttggctaga aagagactat agccttcaaa atactggtgg
     3121 tctccaacca caagatagcc tgtttccaac tctttgacaa agtaaggatt ttcttccttc
     3181 ttgatgaggt caattctctg acaaataagg cacatattag tccaccaacg tgctcttaag
     3241 ataagcatcg accattcgtt ctgttgcgat caccgagtca atatgggtac gctcatagga
     3301 atggctagac tctataccag caccgagaag ggcgtgtttg acttctgccc ctgcagacat
     3361 agccgctgaa gcgtccgaac cataaaatgg atagatatcc agcttaaatg gaatatcttg
     3421 ctctttcgcc aaagccacca aatgttgacg gaagtcatag tgataaggtc cagaagcatc
     3481 cttgacacag atagacactg tatattcgtc tgtttgctgg tcatctccca tggctcccat
     3541 atccacagcc agatattcta ctacctgagc aggaatgtta gaattagcac catgtcctac
     3601 ttcttcaaaa actgaaaaag caaaatgagt tgttactggc aattcaatct tctctttctt
     3661 ataaatacga agcaggttga gcaaaatcgc tgcgctgacc ttatcatcca aatgacgaga
     3721 cttgataaaa cctgtatcag tcacaacagt tcgtggatcg aagctgataa aatcaccgac
     3781 ctcaatccca agagcacgag tttctttttc attgcttact tttacatcca aacgcacttc
     3841 catattgtcc tgcgtgcgtt ctgcagttcc tgcatccttg tagacatggc aagaagtttg
     3901 gtggatgagg atggttcctg ataccttttg acctgtgcta gccacatgaa cggtacagtt
     3961 ttcaccttca atcatgttcc aaggaaaacc accgatacag tccaatttaa gacgaccatc
     4021 tggtttgaca gcacgaacaa tagcacccag cgtgtccaca tgggcagtca catagcgatg
     4081 ttgctcatca ttttgacctt tgatggtcac attgacacca cccttggctg tgcgaactgg
     4141 ctggtaacca aaaccttcta gagtcttgac taaataattc gaaatttcac gagtgaagcc
     4201 cgttggcgat gcgatggctg tcagttcttt gatatattct actgtttgat tcatttcttc
     4261 acctctttcg ctacctatta taacacattt atcatcggat aaaaaaagaa aatcactcct
     4321 gtagacttgg ctacaaaagt gatttaagtg attattccat ttcaaaaaca tcgctttctt
     4381 gcttgtttgg tagaaccaat gagagcaaga ttccaacaat ggctggcacc aaccatggga
     4441 gagatgcctt ggcaaaagga agaacgctaa caagatttgc aagaaactca accttaaacg
     4501 agcttcctag tacgcttgca atggcaataa ctgtaaccac agcaattgtc aactgcatac
     4561 ctggttttga aagggcaaca aatttgttga caatgacaat cataacgata gcaatcgtga
     4621 ttgggtacaa gataaccagt actggaattg agtacttgat aatcgcatca agacccaaat
     4681 tggcaatagc aaatccaatc aaggtaaagg ctgtcgcata aaccttgtag ctgatttgtg
     4741 ggaagcgctc attaaagaac tcagctgttg acacaatcaa accaacagtc gttgtgaagc
     4801 aggttacggt aaccatagct gcaaggaaga gttgagctgt tgagccaaag atttcttgag
     4861 tggcttgtga caagatgtaa acacctggtg ttccaccctt catcgcttca gctggtactg
     4921 ggaaatgatt tccaagaaaa cctaaaccga tgtaaagagc gctgaaggca agggcaacaa
     4981 cgataccaac aacccaaata gttgaaatgt attctttctt acttgaaaat ccaagttgtt
     5041 tcaaggtttg aactgcgatt acactaaagg ccactgaggc aagggcgtcc aaggtattat
     5101 aaccttctag gaaacctgta ccaaaggcag aagcttgata agcagctgaa gcagcttgag
     5161 gacttgttcc accatatttg atagctccca gaacgaccaa gataacaatc aaaattgcaa
     5221 agactggcgt taaaatacgt ccaatgcggt ctaagatttt tgatggatta agcgaaatca
     5281 aataggctgc cgcaaaatac agaaccgtaa atacaatcaa gccaagtcct ttatttgcat
     5341 ccgacaaaag ggggctaatc cctacttcgt aagctgttgt agcagtacgt ggggtagcaa
     5401 agaatggacc gattgacaag taaagaactg agaggtaaag agtcgcaaac caaggcgcta
     5461 tcttcgttga aatctcgtag atatatcctt taggatttag cgttccaata ataagggtca
     5521 agacggcgat accaacgcct gaaaagacaa aacctgcgat ggcaggaaga aaatgttctc
     5581 cagatagagc acctagagaa ggcggaaaaa tcaagttccc cgcaccaaaa aatattccaa
     5641 acaggagcaa acctgttagg gtaccttttt tagccataaa aatctccttc atatttataa
     5701 aatactgacc tagtatacca cgattaggag tctgaaaaaa gcatcacgag gcaaatatta
     5761 aatgttttca attttcttaa aaataagaat tatctaaaaa taaaactctc ctacccagtc
     5821 cacaccaagt aggagaaatg caaaatttta aagttcttca aaggctaaca tgccaccctg
     5881 gacattgata acattataac cttgttctaa caggaattgg caagcacgcg ccgatctcat
     5941 tccagatttg caaataatat aatgcaagcg atctttgtcc aattaatcat aactatcagt
     6001 caattgacta agcggtaggt tgtgggcacc ttctaaatga agagctgcaa actcatccac
     6061 ttctctcaca tccactagag aaagctggtc gttttggtaa agctggtaaa atacgtcaaa
     6121 ggctatttct ttcattcttt ttcttctaat actcttcgaa aatctcttca aaccacgtca
     6181 gcgtcgcctt accgtgcgta tgttaccgac ttcgtcagtt ttatctgcaa cctcaaagct
     6241 gtactttgag cagcctacga ctagcttcct agtttgctct ttgattttca ttgactataa
     6301 aatggtttta attctttttt tcaaatctgg cactacttct gcctcaaacc aaggattttt
     6361 ggccatccag atttgatttc gtggtgatgg gtgaactagc ggaaaatagg ctggcagata
     6421 gtctttatag tgtttcaccc tctccgttac cttcccactg attttctcct gtaaatagta
     6481 ggcttgggca tattgcccaa tcaagagggt taactgaata tcaggcaatt cctgtaagag
     6541 ctgcggatgc catttttctg caaaatctgt acgaggcgga agatcacccg acttgccatg
     6601 tcctggaaag tagaaatcca taggcaaaac agcaaaataa cctgaattgt aaaaggtatc
     6661 ttcatccaca cctagccagt cccgcaagcg gtcaccactt ttatctttcc agtaaaggcc
     6721 tgcttcttga gttttaagtc ccggagcctg accgatgata ttgatgcgag cagtttttgg
     6781 cgctgcaaag agaggctcaa tgccacgctc tgtatagctg gcattctgtg aatccgccat
     6841 gatagcctgt ttgattcttt cgatttgaga catctacttt ccctccaaaa agaagtccaa
     6901 gcataagatc tcagacttct atcgttttat ttgatcaatt cgtaaatagc ttcggcataa
     6961 attgctgctg ctcggaaaag atcatccaag gcgataaatt cattggcttg gtgcatggta
     7021 tcaatcgagt ctgggaacat agcaccgtag gcaactccgc gttctagcaa gcgaccaaag
     7081 gttccaccac cgatgacttg ttcatgacct tgtaggcctg tttgtttttc atagacattc
     7141 aacaaggttt gcacaagtgg atcttccatt ggcacatagt gaggggtatg accatgttct
     7201 gatagactga cagaagcaac tggcaagttt tctaggattg atttgatttg ttctggactt
     7261 gttccttttg gatagcggat gttaagggca atggtattat cagcacttgt ttcatcgaag
     7321 cggaagactc cggcattcat agaaagagca cccatctttt catccacatg agcaatcttg
     7381 agattttcac cctcatgatc gttcaagaga attttacctg cgatgtcaag gtagtctttg
     7441 gctggaccag caaagccaaa ctggctgagg aagagggcaa ggtaagttgc gccattgaca
     7501 cctgaagcag gcatagcacc gtgggctgat ttaccaatga tcgtcacctt gtatttgcca
     7561 gcttcttctt ggagttctcc tctaagtttg tgttctgcaa caaaggcatc tagtttagct
     7621 tgcaagtcag ccaaatcacc tgaaacgact gctgttgctg attctggtac catattttca
     7681 cgtaaaccac ctgtaaagct gtgaagacgg gcagcacctg tattttctcc tgcaaagtgg
     7741 agatattccg tgatatttcc tttttcacca ttgatgattg gaaattcagc atctggtgag
     7801 aaaccgaaat ctggtttggc aggtcctacg tgctcaaagt agtagtccat gtctgcccag
     7861 cctgattctt cgtctgttcc aacgatgaag cgaactttct tagaagttgg aagacccaat
     7921 tctttgatga ttttcaaacc atagtaacaa gctgttgtag gacccttatc gtccgaagcc
     7981 ccgcgcgcat aaaggcgacc atctttgata gttggtgtgt aaggatctgt atcccaaccg
     8041 ctaccagctg gaaccacgtc catatgggca aagattccga gaacttcttc tccatcacca
     8101 aactcaaaat gtcctgcata gttatcaaca tttttagttg gataaccatc acggtctgcg
     8161 atttcaagga atttttccaa ggcttttact ggaccaggtc caaatggatg ttgggcatca
     8221 gccttgctat catcacgttc tgagttgatt tccaaaaggc taaacaagtc agccaagagg
     8281 tcttctttgc gtttttctac ttctgctgta aagtcaattg ctatcatttt ttcttcttcc
     8341 tatctttttt cgatgatttc atctactggc aagcggtagc ttggttccaa tttgtcgtct
     8401 gtgtaaccca ctgtgatcaa gagttctggg cggaaacggt cttcgatttc caaaacttca
     8461 ttaacttttg atttgtcaaa accaaggata atattggaac caattccttg gtctgtaaga
     8521 gcgagaacca agttcatagc aaccaaacct gcattgagtg ctaggtagtc gctgacttgt
     8581 tgttcattgt agcgtgcaaa ttcagctggc aaatttttca tgaagtattg aagttgttct
     8641 tctgagaaat tgttagcacc accaactcgg gcaatcttac gagcgcgttt ggcaaggtct
     8701 gtatctgtaa atagggcaat ggttacaggt gctgatgata cctgctcaaa gtttgaacca
     8761 taagccaact ttgccagttc agcatttttc tcacgaacaa ctacaaattt ccaaggctgg
     8821 ctgttgtggg cgcttggcgc caaggttgca atttcgatag ccgtacgcac atcttttgga
     8881 tcaacaggct tatcagtgaa atgcttggtc gcatgacgtt ttttatttaa ttcaagaaat
     8941 ttcataatcg atttcctttt ctaattctac tgcttccatt ctaccataat ttgaaagagc
     9001 ttgcagggat ttttcatgat taagtttttc tatcacagac ataaaagata tatattggtt
     9061 tatcaggaaa gtttctgata aactagcaag tactttacat ttgaatggag acagtatgaa
     9121 aaaatttagc ctattactag ctatcctacc atttttggtt gcctgtggga atcaagctac
     9181 acccaaagag actagcgctc aaaagacaat cgtccttgct acagctggcg acgtgccacc
     9241 atttgactac gaagataaag gcaatctgac aggcttcgat atcgaagttc taaaggcagt
     9301 agatgaaaaa ctcagcgact acgagattca atttcaaaga accgcctggg aaagtatctt
     9361 cccaggactt gattctggtc actatcaggc tgcggccaat aatttgagtt acacaaaaga
     9421 gcgtgctgaa aaataccttt actcgcttcc gatttccaac aatcccctcg tccttgtcag
     9481 caacaagaaa aatcctttga cttctcttga ccagatcgct ggtaaaacaa cacaagagga
     9541 taccggaact tctaacgctc aattcatcaa taactggaat cagaaacaca ctgataatcc
     9601 cgctacaatt aatttttctg gtgaggatat tggtaaacga atcctagacc ttgctaacgg
     9661 agagtttgat ttcctagttt ttgacaaggt atccgttcaa aagattatca aggaccgtgg
     9721 tttagacctc tcagtcgttg atttaccttc tgcagatagc cccagcaatt atatcatttt
     9781 ctcaagcgac caaaaagagt ttaaagagca atttgataaa gcgctcaaag aactctatca
     9841 agacggaacc cttgaaaaac tcagcaatac ctatctaggt ggttcttacc tcccagatca
     9901 atctcagtta caataacact cttcgaaaat ctcttcaaac cacgtcagct ttatctgcaa
     9961 cctcaaagct gtgctttgag caacctacgg ctagcttcct agtttgctct ttgattttca
    10021 tattgagtat aagatatatt aaaagcgatg ggatcagcca atcgcttttt tagtttgcat
    10081 tggttatttt aggaaactct tacaaaaaat caaaaaaatt cttcacatcc tctacatacc
    10141 tatgcttttc tattaagctt gctaatagtt ccagattgtg cctctgatag ttatcttcac
    10201 gacgtagttc ttcatacatt tcgataaagg gaaacccctt ggatttggca aattctaact
    10261 cagcctcgta atcataagcg actttacgaa ataggatatt taccaattcc ccatcttcaa
    10321 cctctatcac ggcatactgg gcacggtgat tttttaacgc ctcccaatta aaatagggca
    10381 tgccaatcga ccctggattg atgatttgtt gcccttgact accataacga agcaactact
    10441 tgtgaacatg accataaact gccacgtccg tttccgcatc tagcagttgg tcaaatttct
    10501 ctgtatcatt ctcaactagc aagtcaccac catagttttt gtcaggtaaa ttatgagaga
    10561 tagaaaagcg caatccgtca atttctttct tttccagcaa aggcaagctt cgtagccaga
    10621 caatcgttgc aggatccatt cgctccatca aatactgtgt catacgcaag agctgaactt
    10681 cctgtgggtc ttctaagcca tattgcccat ctaaagcctc aaggacacaa tcatcccaat
    10741 tgcctcgaac acttgccgtg ataggaagtt cctttaacag agcgaccaag tcatttgcac
    10801 ctggaccagg gaggaaaatg tctcccatga gccaatattc actggctcct tgagttttag
    10861 catctgcaat cactgcttct agcgccgtcg cattgccatg aacatctgat aaaattgcga
    10921 ttttatggtt tattgtggtt tccttccgtt tggtaatcta ctctttcttc cgccacttga
    10981 agcaagattt ctgtttcctg cgggttcaac ttggtttgca cagcctctgc tactgctctt
    11041 ggtactccaa cttcgacaat ctcatccaca ctggcttcct tgattttggt cagagacttg
    11101 aagtgcctca tgagattttg cttgcgttta ggtcccagac catcaatccc atccaattga
    11161 gatgagaaag aatttttgga gcgcagttgg cggtggaagg taatggcaaa gcggtggacc
    11221 tcatcttgaa tgcgttggag gaggaaaaat tcctgagaat tgcgagacaa gtccaccact
    11281 tccagcggat ctccaaagag caattcatgg gtttggtgct tatcattctt ttgcagacct
    11341 gcaattggaa tatccaagcc cagttcttct tggatgactt gcttagcaat attgacttga
    11401 ccttgccccc catcaatcac aatcaaatct ggaggagtca aagcctcacg ctgtactcga
    11461 ccatagcgtc tgcgaatgac ctctcgcata ctggcatagt cgtctggccc gactacggtc
    11521 ttgattttat acttacggta atccttctta ctaggcttgc cgttgacaaa gaccaccatg
    11581 gctgaaacag gactagttcc catgatgttg gagttatcga aggactcgat gcgaactggg
    11641 gttgggattt gaagcaagcg tcctagattt tcaatagctc cttgggtctt ctcgacagat
    11701 ttctctagca ggttgaactt ctgctctagg ctaacacggg cattttttat agctaaattg
    11761 accagctgtt ttttctctcc acgttggggt ttgagaatct tggtatccac caaagccttg
    11821 acagcttctt cgtcaatatc ctgcggaatc agtacctcat tgggaactag gtgagatttt
    11881 tcttgataga attgtcccac ataggtcaag aaatcctcat ctggatcatt gaagtagggg
    11941 aagagattga cagcgcgctc gatgagcttg ccctgacgaa caaagaaaac ctgcacacac
    12001 atccagccct tatccacata gtagccaaag acatcgcgat tttggagatc cttagccatg
    12061 acccgttgct tggttcgaag cgttccaata gcctgaatca ggtcacggta ttccgccgca
    12121 cgttcaaact ccatagtctg ggctgccgct gccattttgc cctttagctc atcaatgatt
    12181 ttgttatcct gccctttcag aaaatcagaa acctcctggg ccatagactt gaaataagcc
    12241 tcatccttct tacagatggt gtgagccata cactggccga tatggtaata aaaacagacc
    12301 ttagagggcg ggttggtaca cttacgaaaa gggaatatcc gatccagcaa ccgcttgatt
    12361 tcattggctg cccccacatc gggatagggt ccaaaataaa gacctccgtc ctttttgacc
    12421 tgacgagtga taatcaagcg tggatagcgc tcattggtga ttttgatgaa aggataggac
    12481 ttgtcatcct tgagcatgat attgtacttg ggcttgtttt ccttgatcag gttgatttct
    12541 aggagaagtg cctcaatatt agactccgta acaataaatt caaaatccac aatttcagac
    12601 accagagcct ctgtcttggt atcatgactt ccacgaaaat aggaccgtac tcgattacgc
    12661 agatttttag cctttcctac atagataatg gtgccatttt tatccttatg aatgtagcaa
    12721 ccagggctgg tcggcaagag ctctagtttt gatttaatca agttgttcat agttccatta
    12781 tagcaaaaaa agtagggaaa gatagtaccc tactcactag tctcatatat ttttcggagg
    12841 tttgcaacat cctcttcctg gataccataa aaggaacctg ctggttgcat gacagacttc
    12901 tcatctgtat ggtccaagcc aatcgcatga cctaactcat gttctgccgt atggacaagg
    12961 cgttcatagg agtagccata gtatggattg gacaaataat aatgattcaa ccgcaccgtt
    13021 acggacaaga attgccctgt taagagatta gtttgacttt ccgcctctcc tgccacagga
    13081 gtgcctccgt cgttcatctc cgtagccgta atatccgcct tactagactc agtcacgagt
    13141 tcaaagttaa aagcaccagt ttgattccag ttctggattg cttctaaata agcctcttga
    13201 aagcgtgaat ccatctgcgg atccaggtaa atacgagcag aggcctgtgc ccaccttcct
    13261 tcagaatgct ggtgactatc tgtctggctt aacttaggca gttgccctgt tttctcccat
    13321 tggtcaatac tttgttgacc aatttttact gaccgttctg cttgctttag cgctccttga
    13381 aaatccccgt tcagatacca gagaagtccg aaagcaagca cacataagag cacaactatc
    13441 caaaccagac gccaaaacaa acgccacaca aaagaaaaga aagcccctat caaacgaaaa
    13501 agccagcgca tgtctctcca cctttctagc aaataagaat tattttacta aaagaagcta
    13561 aaagaaatct aaatactgac tttttcatct taacgtccta ctattttttt gagtaactgg
    13621 atagctttgt attttaaagg cgatggatgg taacggaaag tacctgcttt gcgtacaata
    13681 tagccattaa aattctgttt aaaacgcaaa acaccatcac ttccatcaaa aatcccttga
    13741 atgcctagga agttgtattt aggtattcca cgttttatgc tttccaacat aacatatttt
    13801 tgaagcagtg caggggcata gaacttatta aactcagtgt aggaaccact aaagagataa
    13861 gtcgtttcct gaggcatata aacaaataaa ctcccagcta aaacaatatc ttcttctcca
    13921 tatttttcaa tcaagtctcg cgcttctgct tttcgaactt caaacgtttc aaattgacta
    13981 gaatattctc tcagttgatt ttgttttttc tcagaatgag gatttttact caaatcaagt
    14041 cgcaacttgt ccaagttttc ttctagttta ctttgttcac cttgcaattt gctcatatac
    14101 tccgaaaaat tcaagcttgc tatgagaaac tccgcttgtt ctccaaaagt atcataaaaa
    14161 tgctcataat attctaaact tttatcacta tattctctac gttcagaggt ttcttttgtt
    14221 atattcttaa aaatcgatag ttcttcacgt tttaactttt tcaaccgaat gccaaaggtt
    14281 tcagcctttt tcaccaaggg tttacccttt ttgctaaaac ttttaagcaa actcttttca
    14341 gttaattcag ttaaatcttt atagtataac caatctggtt ctccacctgg gtaacctgtt
    14401 gttaagccat caaattgata acctaaatca gtcaaacctt gaataatact ttttttctca
    14461 gcatctattg gattaccttg gctatcaaaa gtttgataag tttcataggg ttttacaagc
    14521 aactctaata caccattttg cttggcatat tcttttaact ctgcataaaa aactggaaga
    14581 gcatcttgtt gggtataaat cggccccgaa ttgagttcca tatgcagacc acccagcatg
    14641 ggcaggctat aaaccagagc tgcaacttga atttctcctt cttgtttcaa agcaagataa
    14701 acaattcgag cccctctttt ttctagcaaa tcccccatct ggacagattg cataaaggaa
    14761 cgagaagaaa cctgatcaga ataagtctga aactcttctt tcgtgagtgt tgttagtgcc
    14821 atatacttac tttctatgtt tttttcttaa tgttttacgg aaatcaagag caagtcttaa
    14881 cagaggatag agaggatgag tgggcattgt aaattcaccc aagtattctt caatcgttgg
    14941 attaaatttt tccttaaaat gataaagtcc accattgaga gagttttcaa caccacctaa
    15001 attttgccag atcatacctc gttcaaaggc atagcgagcc gtttcatacc aagttaaaat
    15061 tggtgcattg taacgtttaa aatcatcatc cataccagca tatatattga cagaggtagt
    15121 accaaattcc aaactcaaag tagccgctaa aggaactctc gcttgaccta catctatata
    15181 ttcctgcaag aaggtcaatt cctctaacaa acgttctttt tccttcttct gcgcttctac
    15241 ttttgaagtt cgagtcgact cagtaaaggt ctcttccaag gctctatttt tcgctaactg
    15301 ttcttctaac tcttgcgaac gtttagaaac atccaaggtg gccaaggtga tataggcctt
    15361 gtccttaaaa ttatctaaca attttttata ataggcttca ttcctcaaat gaatctcttt
    15421 tcgcttctca gtttttttca tcaactccga aaatgaatct aatagttcca gtccaccata
    15481 ttgaatctca agccctttgt ttcgtgctgt tcgaatagcc tgttttgttg acttggaaag
    15541 tttatcttct tcaaaatttt ccttgtatat tttcgcctga atacgaggtt gaatggtgtc
    15601 tcccatttcc tccgtttttc ctgaccacct tactcccatt tgttgcaaac tatcaataat
    15661 agccagattt tcaggaaatt ctgtcttttc ctgattgatt aaactttgag ataggcaaat
    15721 acttgggtca aaagtcacaa aaaccgctct cttactgcga gcataggact taatagactg
    15781 aatggcaaaa ttcaagagtt ctttatcccc ataatccaat ataggtcctc ttgggatgta
    15841 aaacatttta tagcctagcg gaagagttct aatcaaaata ctagctgtcg ccagtaattt
    15901 ttcttccctg taaacaccaa acttctcatg ttgccaatta gacttaactt cctcccaagc
    15961 actactttgt aatacattgg ctaattcatg ttctttgaca aactgatcat attctaatgt
    16021 gggaatgcca atttgataac ggtacatttc ctactctttt tcctccagta ttttattact
    16081 attctactac tttcgtttga aaagtctagt gaaaacatat tttattttag ttctactccc
    16141 cctatgctga agttcaaact aagtcagtct ctcttctaat ttgaaatcaa ttggtagggt
    16201 tgttaaaaaa acttccaatt gtttttccca gtagtaccac tcgtgagttc cagcgctatg
    16261 gctataggtc acatcaaaac ctagtttttt gagatttttc actgcaagat tattggcttc
    16321 gtacaagaaa tcctgttcgc cacaccacgc ccaaagtttg gtctttttat ccgatttttt
    16381 agccagactt tcaagagaat agggactagt tgtccagtct ctaatctctc caaaaacacc
    16441 tctccagtag gctggacttc ccagattttg actttcagga gaaaagtttt gaaagctgag
    16501 ggcacctgaa aaactagctg catgagaaaa acgatttgtc gtaagagcca gtttgaagca
    16561 gccgtagcct cccatagaaa gaccagcgat aaaggtcttt tcacgcttgc tcgtcatatt
    16621 agggaagaag cgtttcagaa cctgtggcaa ttcctctgct agagccgtgt agtagtcaaa
    16681 accatactgg gtatcggtat accaaccatt gctggtattg ggcataacaa cgatgagatt
    16741 agttcctcga agcaagcgtt ctacattggt ccgcttaagc caactattat gatttccaga
    16801 catcccgtgc aaaaggtaca agacgggaat atcttcacac tctggttctt ccactcgatt
    16861 ggcatcaggg tagaggacat tcacccccca ctccatatcc aatacttgtg agtaatactc
    16921 gattttcatt actgccatga ttttctcctt ctatttttct ataagaaaaa gccgaaactc
    16981 gactttctct ctgtttattt caacgattat tttgcttcca tgactactgg taaaatagct
    17041 ggacgacgct tggtttggtc aaagagatac ttggtcaaat tatctcgaac cttcccttta
    17101 agatctgccc agtcaaagtc atctccttga agataatctt ctaccgtttg gttaatcaat
    17161 tctgaacttt cacgtagaat atcgcgactc ttcttgagat aaacaaatcc acgcgtgtga
    17221 acacgagccc tagccacaat tttcttctca cgacggttga ctgtaatagc cacgatgaaa
    17281 attccatcct ctgacaagac cttacggtca cgaagaacaa catttccaac atcaccaatg
    17341 gcattcccat caatcaagat atctcctgct gaaaccgatc cagctggaac aaagtctcca
    17401 ttctcgtaag ccatggtcgt ccccttttta ggaatgaaga tgcgttctgg caacatccca
    17461 actgccatgg cagccttagc gtgagcatcc aactcacgat actccccttg gacagggaag
    17521 aggtacttag gttgcaaaag attgatcatc agctgcaaat cacgcacatt tccgtgccct
    17581 gatacatgta aactttgggt aatcaatttg acaaccccac ctgcctgata aatcatattt
    17641 tccacacgcg caacaaaggc ttctttagca atagacggag ccgtagcaat atagaccagg
    17701 tccccatcct tgatttctac ataacgatgg cgaccaatcg acatcttacg aagtccattg
    17761 ataggttcac ccatacgacc tgtctcaaga ataatcaact catggtcttc aaagcgagac
    17821 atatctttag gcttaatcaa gagaatttcg ttggctaaag acaacttctt aagacgaatc
    17881 gctgtacgga cgatattttc aatatcaaat cctgtcaaga cgatacgtcg acctgtttta
    17941 tccgcagcgt caaaaatctg ctgaatacga gaaagattac tggaaacagc tgcaacgatg
    18001 atacgacctt cccagtcagc aatagtttgg gtaatttcat ccctaacttc actttcacta
    18061 gccacctgaa tattgctgtc tgcattggcc gaatcactga ggagagccag gacgccgtca
    18121 cgaccaatct ctgccaaacg agcaaaatca gttgcataag attcactagc cgtttggtca
    18181 aatttgaagt cacctgtata aacgatgctt ccttccgatg tcttcaagac aattcccaga
    18241 ctctctggaa cggagtaagt cgtagggaag aaggaaacca ctgtcccacc aaaatcaatc
    18301 tccgtattct catcaatgac atggaaatca ttaaatttct taacggcatc atttcctttg
    18361 acaaagagct ttgccaactc aatggtcaac tcagacccaa atacaggaac tttagactct
    18421 gccaagagat aaggtagagc accaatggca tccgcatgcc cgtgggtcaa gaaaacccca
    18481 gcaatacggt cgctattttc aaaaaggtaa tccatgtttg gaatcaccac atcgacccct
    18541 aattgttcat tttcaggata ttttaaccct acattcaaaa caaaaatgga ctctccaatt
    18601 tcagcaatgt acatattttt tccattctca cgcacaccac caagtgttgt taaactgata
    18661 ttactcattt ttcctccaaa atcttagttt atcttgatta tagggcaatt ctaccctctt
    18721 attctaaaag ttctgatact ttcagccgaa tcttttccta ccattatacc atttttttga
    18781 tgattttcaa aatgaaggtc tgttttcaaa aaagagttga tttcccaact ctttcctaac
    18841 ttctactctt tttccatcaa aaaatcataa atttcttgca ccgtacccag cgccatcatt
    18901 tcttggtctt taacggtttg tttgagattt tggtaaattt gactttctcc tatctcccgc
    18961 tttggcgcct ctttattgac tgtcatcaca ccatctttta tcgtcacaaa gcctagttct
    19021 tcaaatactt gaatcatctt gaccagcaag atttgttgaa tattaagata tgcagccaaa
    19081 tctttcagct tgtagcgaat atcaaactct gggaactggt aaatagtctt gtacaattta
    19141 gcaaactgat ctctagtccc ataacctgtc agataatagg tcttgtcaat atcatttttg
    19201 aaatagacag cagagaaatg ctgttcctga aaaatggtct tcagctgagt aatatcctct
    19261 ggaatgtttt ttacgacaac agcttcacta gccgcaagat ttggcagttc tccaggaaaa
    19321 tccaagactg gaacaccttc tggcaagact gcattttttc cacgaatgtt aaaaagttga
    19381 acaccttcca ctcgcgcatc caccatcatc aactggaggg cagtttggcc attccattgg
    19441 ttgacagaca atttaaccgc taactctaga ttcttggttt gagaaaactc tgtcgcccat
    19501 ctgccttgac caaaggctac cacttcaaaa ctcgcctcac ccttggaaat tttcagcttt
    19561 agatgggcat tacctgcccc catagtacga gcactttcga cctgaaaatt cttgatataa
    19621 aaaataggtt tctgattatc cattccaaaa ggagctaaac gttcaaaact tttgaccgtt
    19681 tccaagctaa gtgcctccaa atccaactct tcatctaggt ttaacttatt cttgccacca
    19741 gcatctgcac ctttttcacg aacataatct tccaaaacct gagataaatc tgagagttgc
    19801 tcaacttcca gcgtcatacc cgctgcacct gcatgacctc caaaggcgat gaagaggtct
    19861 cgatagggat ccagagcttc aaaaatatcg accgcttcca cactacgagc actgcccttg
    19921 gcacgaccgt cttctatatt aagaacaatg actgtctgtc ccaattcttc caataaacga
    19981 ccagccacga ttcctagaac cccaggattc cagccttcct tggccaagac ctgaaccttc
    20041 ttctcaggat ccaccatggt cttggcttct tcatagatag actgaacgat ttccttgcgc
    20101 tcttcgtttt tctggtgaat cataagggca atctcatgcg cttcctcatc atcaaatcca
    20161 gtcaacaaat caatggcagg attgggatca tccaagcggc ccaaggcatt caaacgagga
    20221 gcaatctgga aaccaaccgt ttcttctgtt acttcgttag cagcaatccc agccatgtcc
    20281 agcatttctt gcagaccaat gcgctgggta tgacccaaca tttccagacc atattgaact
    20341 aagatacgat tttcatccgt cagactcacc atatctgcaa tagttccaat agcgaccaaa
    20401 tcaagcaatt ccacttgcac ttcttctaac agggcacaag ccaacttgaa agcaactcca
    20461 caaccagcca aatatttaaa aggataatcc gcatctggat gttcaggatg gacaatagca
    20521 taagcatctg gcagggtttc aggcatggaa tgatggtctg tcacaatgac atctactccc
    20581 atagactgag ccaatgcaat agcctcatga ccagcaaccc cattgtccac cgtcacaatc
    20641 aaggaaatcc cttcttgctc gataaagtat ttataaacac tagcattagg gccatagcca
    20701 tcggtaaaac gatttggcag gtaaactcgg cactcagcac caagttgttc caaactttcc
    20761 ttcacaatag aagccgaagt catgccatcc gcatcatagt ctccataaac gagaatattt
    20821 tccccttctt caatagcctg acgaatccgc tccactgcct tgtccatatc atggagcaga
    20881 taagcatcat gtaagtcctc caaggaaggt tctaaaaact tcttcagact ttcttggttc
    20941 tgaatccctc tctcaaacaa taaccgagcc acctcaggac ccagtccagc cttcttggct
    21001 atctttgtaa aatccgcatc ttctacctgc agggcaaact gccattcata agtaggtgtt
    21061 atcaaaaaga catccactct ttctaagaat tctattgctt cattataaca tgatttagac
    21121 gttttctcta tccagattgc ttttttataa cattttatag tatattgaaa ctagaatagt
    21181 acacctctac ttctaaaata ttgttagaaa tcgatttgac tgtcccgatc gatttttcct
    21241 gttcttattt cactatagtg aattttttca gatatggttt gacaagaaca ttcttttatt
    21301 gtagaatcat gtcataaaat ctaacacaat ggagagctct catggcttta gtagaattta
    21361 aaaacgtcga aaaatattac ggagactacc atgcactccg cgacatcaat ctccgttttg
    21421 aaaaaggaca agtcgttgtc ctactcggac catctggttc tgggaaatcc actcttatcc
    21481 gtaccatcaa tggtttggag gctgttgaca aaggaagtct cctagtcaat gggcaccaag
    21541 ttgctggtgc cagccagaaa gatttggtac ctcttcgcaa ggaagtcggc atggtttttc
    21601 aacattttaa cctttatcca cacaaaacgg tgttagaaaa cgtgacactt tcgcccatta
    21661 aagttctagg aattgataaa aaagaagctg aaaaaaccgc ccaaaaatat ctggaatttg
    21721 taaatatgtg ggacaagaaa gattcctatc ccgccatgct atctggtgga caaaaacagc
    21781 gaatcgccat cgctcgtggt cttgctatgc atccggaact cctcctcttt gatgaaccaa
    21841 catctgctct tgatcctgag actatcggag atgttctagc agttatgcag aaactggcgc
    21901 atgatgggat gaacatgatc atcgttaccc acgaaatggg ctttgctcga gaggttgcgg
    21961 accgcattat ctttatggcc gacggagaag ttttagtaga tatgacagat gtcgataact
    22021 tttttgacaa tccaagcgaa cctcgtgccc aacaattcct cagcaaaatt atcaaccacg
    22081 aaagtgacaa agtcaaataa ggaggcgcct atgaaaaaaa attcttttta tcagcattat
    22141 tgattagcct tttcggcctt gctgctgcca aaccagtcca ggctgatact agtatcgcag
    22201 acattcaaaa aagaggcgaa ctggttgtcg gtgtcaaaca agacgttccc aattttggtt
    22261 acaaagatcc caagaccggt acttattctg gtatcgaaac cgacttggcc aagatggtag
    22321 ctgatgaact caaggtcaag attcgctatg tgccggttac agcacaaacc cgcggccccc
    22381 ttctagacaa tgaacaggtc gatatggata tcgcgacctt taccatcacg gacgaacgca
    22441 aaaaactcta caactttacc agtccctact acacagacgc ttctggattt ttggtcaata
    22501 aatctgccaa aatcaaaaag attgaggacc taaacggcaa aaccatcgga gtcgcccaag
    22561 gttctatcac ccaacgccta attactgaac tgggtaaaaa gaaaggtctg aagtttaaat
    22621 tcgtcgaact tggttcctac ccagaattga ttacttccct tcacgctcat cgtatcgatg
    22681 ccttttccgt tgaccgctct attctgtctg gctacactag taaacgcaca gaactactag
    22741 atgatagttt caagccatct gactacggta ttgttaccaa gaaatcaaat acagagctca
    22801 acgactatct tgataccttg gttactaaat ggagcaagga tggtagtttg cagaaacttt
    22861 atgaccgtta caagctcaaa ccatctagcc atactgcaga ttaaggagga caccccatga
    22921 cagatttatc atcttggaca gcctattttc aggattttgg acaatttttc aatggtttcc
    22981 tctttactct tgccctagcg attggatcct ttatcctcgc catggtctta ggaatcttct
    23041 ttggtgccat gtcaaccagt aaacgtccaa ttttacgcat tttagctcac atctttgtgg
    23101 aattttacca aaacactccc ctcttggtgc agtttgttat tgttttttat ggcctacctc
    23161 ttatcagtga ccatatcatc atgattccat tttattggac agccgttctc tgcgtgggac
    23221 tctatcacgg cgcttatatc gctgaggtta ttcgttcagg gattcagtct attcctagtg
    23281 gtcagatgga ggccgccttg tcgcaaggtt ttacctatat cagtgccatg cgcttgatta
    23341 tcttgcctca ggccttccgc atcattctcc ctccattgac caaccaaatt gttaacctca
    23401 tcaagaacac ctctactgta gctatcatct ctggagtaga cttgatgttt gtgactaagt
    23461 cttggtcggc tctcaacgga aactatatcc cagccttttt aggtgctgct cttctctact
    23521 ttgccctatg cttccctgtt gcccagtttg gtcgcaagat ggagcaagcc aacaaaaaag
    23581 cctattcact ttaggaggtt actatggaat ctattttaga agttttaacc ccagataacc
    23641 tagtctttat ctttaaagga tttggcttga ccctctatat ttctctgatt gccatcatcc
    23701 tctctactat catcggtacg gtgctagctg tcatgagaaa tggcaaaaat cctatcttac
    23761 gcattatttc cagtatttat atcgagtttg tgcgcaacgt tcccaacctt ctctggattt
    23821 ttactatctt tttggtgttc aaaataaagt ccacaccagc aggtattaca gcctttactc
    23881 tctttacatc agcagccttg gctgagatta ttcgaggcgg cctcaatgcc gtagacaagg
    23941 gacaatacga agcaggaatg tcacaaggct tcacctcagc ccaaatcctc tactacatca
    24001 ttctcccaca agccatccgc aaaatgctac cagccatcat ttctcagttt gttaccgtga
    24061 ttaaggatac cagtctcctc tactctgtta tcgccctaca agaactcttt ggagccagcc
    24121 aaattctcat gggctgttat ttcgaaccag agcaggtctt cagtctttac atcctgattg
    24181 ccctcatcta cttcagcttt aacctagcaa tttctagcct gtctcatatg ctagccaaac
    24241 gttggcaaca agctgcagaa taatactctt cgaaaatctc ttcaaaccac gtcagcttca
    24301 ccttgccgta tatatgttac tgacttcgtc agttctatcc acaacctcaa aacggtgttt
    24361 tgagcagcct gcggctagct tcctagtttg ctctttgatt ttcattaagt ataaacagcc
    24421 actctccagt tcaattggag agttttttga tgatagtaga tatttataga cctcaatttg
    24481 acaccataca ttttctatga aatcagtcaa aggactactc tttatcatag ctagttttat
    24541 cttgactctt ttgacttgga tgaacacttc tccccaattc atgattccag gactagcttt
    24601 aacaagccta tctctgactt ttatcctagc cactcgtctc ccactactag aaagctggtt
    24661 tcacggtttg gagaaggtct acaccgtcca caaattcaca gcctttctct ccatcatcct
    24721 actaatcttt cataacttta gtatgggcgg tttgtggggc tctcgcttag ctgctcagtt
    24781 tggtaatctt gccatctata tctttgccag catcatcctt gtcgcctatt taggcaaata
    24841 catccaatac gaagcttggc gatggattca ccgcctggtt tacctagcct atattttagg
    24901 actctttcac atctacatga taatgggcaa tcgtctcctt acatttaatc ttctaagttt
    24961 tcttgttggt agctatgccc ttttaggctt actagctggt ttttatatca tttttctata
    25021 tcaaaagatt tccttcccct atctagggaa aattacccat ctcaaacgct taaatcacga
    25081 tactagagaa attcaaatcc atcttagcag acctttcaac tatcaatcag gacaatttgc
    25141 ctttctaaag attttccaag aaggctttga aagtgctcca catccctttt ctatctcagg
    25201 aggtcatggt caaactcttt actttactgt taaaaattca ggcgaccata ccaagaatat
    25261 ctatgataat cttcaagccg gcagcaaagt aaccctagac agagcttacg gacacatgat
    25321 catagaagaa ggacgagaaa atcaggtttg gattgctgga ggtattggga tcaccccctt
    25381 catctcttac atccgtgaac atcctatttt agataaacgg gttcacttct actatagctt
    25441 ccgtggagaa gaaaatgcag tctaccttga tttactccgt gactatgctc agaaaaatcc
    25501 taattttgaa ctccatctaa tcgacagtac aaaagacggc tatcttaatt ttgaacaaaa
    25561 agaagtgccc gaacatgcaa ccgtctatat gtgtggtcct atttctatga tgaaggcact
    25621 tgccaaacag attaagaaac aaaatccaaa aacggagctt atttacgaag gattcaagtt
    25681 caaataagta atcatactct cctggaattt cccaggagag ttttttatag ccaaatgaaa
    25741 taagaccgga acgatggaat tttggcattc aaatcaattg ataagaatat tttatagtgg
    25801 agtgaaatag gatacgaaca aattgattag gaaaatcaaa tgaatttata gaaatctttt
    25861 agcagttatg ttatcctatt ctagtttcaa aacgctatag aagcagcatt gtgctagtct
    25921 agattcagtt tactatacta aaacgagtag cttgaaatca aaaaacccac cctcacaggc
    25981 aggttttatc tgtattattc agctagatta tgctttacct tctgaaccga atacgtcgat
    26041 acgttcttca accgatgctt ggatagcttt tacaccgtca gccaagaatt tacgtgggtc
    26101 gaagagtttt ttcttgtcgt attctgcttc gtttgcttcg tagtcacgag caaatttacg
    26161 agttgcgtta gcgaatgcga tttggcattc tgtgttaacg ttaactttgg caacaccaag
    26221 tttgatagct gcttggattt gctcatcagg aatacctgat ccaccgtgca atacgattgg
    26281 gaatcctgga agagcttctg tcaatttttg caagtggtca aggtcaagac cttcccagtt
    26341 tactgggtaa ggaccgtgga tgttaccgat accagctgcc aagaagtcga taccagtttc
    26401 aaccattgct ttagcgtctt cgattggagc caattcacct ttaccgatga ttccgtcttc
    26461 ttcaccaccg atagtaccaa cttcagcttc tactgagata cctttagcgt gtgctttttc
    26521 aacaacttct ttagccaatt taagattttc ttcaactgga aggtgtgaac cgtcaaacat
    26581 gattgaagta taaccaactt cgatacactc aagtgcatct tcgtagtgac cgtggtcaag
    26641 gtggatagct actggtacag tgatacccat tgattcaaca aggttagcga tcaagttgcg
    26701 agcaactttg taaccaccca tgtatttagc agcacccatt gaagtttgga tcaaaactgg
    26761 agctttttta gcttctgctg cgcgcaagat agcttgagtc cactcaaggt tgtttgtgtt
    26821 aaatccacca actgcataac cgttgtcacg ggctgcttgg acaaattttt ctgctgaaac
    26881 gattgccatt ttatcaggcc tcctgtatat ttttatgggt catcccattt acattgttca
    26941 ttttatcact ttttgccaaa aaaatctagt ttttcccgca gtttcgattg attttcttct
    27001 aactccatct atgtaaaccc tttctctccc tagtcttggg cgacttttgg aaaatctata
    27061 aagaaggtta aacgattctc ctccatctcg aaacgataag ctaatttttc atgttctaat
    27121 agactcttaa ccacaaagag ccccatacca gaccccttga ccttgcgact agcattgtca
    27181 gaaaaagact gggctagttt ttcttgttcc tctgagctac agctattttc gataaaaagt
    27241 tctccttctc tttctccaat tcgaactaag ccacctggaa cagagtgctt aatggcattg
    27301 ctgatgagat tagaaagaat caacttcata actgatgggt ttagataagc ctgctgatgg
    27361 gtcaaactat tgtctatctg gagctctctt tccttggcta gcaaggcata atctttgacc
    27421 agattttgcg tcatctggag gaggtcaatt gtttccctat catctcgcaa ttcctgcaca
    27481 gaagagaggg aaagtatctg cagaacatgg tgattgagtt catccacaat ccccaaggca
    27541 actcccagat actggtctct atccttataa cgaccgatat tctctctcat attttcgatt
    27601 aggattttca aactagccag cggtgttttc aattcatgag aagctcctcg taggaattcg
    27661 accttcatct tctccagctg gagaatggct tcattctttt catgcaagtc cgcaataaca
    27721 gtcaagagat gctggtagag gctattgatt tgttccttga gattacctat ctcatcctta
    27781 gaatccacgc gcaatcgcac ttgggaatcc aggtccatca tccgacgggt cacccgcttg
    27841 atttccaaaa tcggtgcaac aatagtccga gcgtagatgt aggccaccaa gagggaaatc
    27901 agaaaggagg ccagcaaggt atagggaaga aactggagac tgatttgctc cgcttccttt
    27961 tgtaaatcca tggaagctag aaactggaga atcatagtac caccgtcttg cgttttcacc
    28021 tcgcgctcct caataaagag agaggttgtc tggcggtctg tgtccagagg aagactgtcc
    28081 ttgacttcta acttgtcctc ggtcatctca cctttgacgg tccccttgat atcactagtc
    28141 tgggaataca agtctaacac ttgctcgata ctctgcctat ctttcccttc tagggactgg
    28201 gcaatggctg ttgccttttg accaatggtt tcctgacgat gactcagata agtcgaagga
    28261 aaaagaaaat aaatagctaa atgaaggcag ataaccagaa cactaaatat cgagaaggta
    28321 tagataaata tctttgcaaa taaacctgtt cgtttcattt tcgctccaat ttataaccaa
    28381 cattgcgcac agtgaggata caatccaagt ctagcttttt ccgcaattcc ttgatataaa
    28441 catcaataac acggtcaaag ggaacctcat ctgtcgcttt ccagacggca tcgataatct
    28501 gagatcgagt caaggcccgg ccttcatttt tcactagata gtccagaatt tccaactctt
    28561 tggcattgat aggcacttct tgacctgcga ggcttgcact gtagctttca aagtccacct
    28621 tggtatcctt gtaagaaaag attcgtcctg tatcgtagta gcgcttgaaa atcgcgtcca
    28681 ccctcacttt taagagggag agggagaaag gtttttccag atagccatct gccaaagagg
    28741 caaaggcact catcttgtat tcctcatcct gaaaagctgt caacatcaag acaggaacct
    28801 gactggtttt acgaatctca gctaggactt ctaagccgtt aagcttgggc atctggatat
    28861 ccagtaaaac cagggccacc tcatagctag aaaattgctc cagagcttcc tgaccgtccg
    28921 ctgcctcaat agtttcatag ccacaatccg tcaaataatc actgaccccc tcacggatca
    28981 tctcttcatc ttctacaatt aaaattttca tactttaact gctctctatt ttttattttt
    29041 cttagaataa atacctactc tattttctat tatagtctct tgctggcctt ttgtctgtaa
    29101 gtaactgatc actagataaa acgttgtgaa attcctttct cataaattcc atagctttag
    29161 tatattatat ttaagcacta aagtacaaag aaaacaactg aaagcaatga ttttcaccac
    29221 tgctttcgga tttattttga attgttaaat agccattcct atccactatt cttgaataga
    29281 aacacaagat gcaatcttta ttccagactc attttttcaa atttattcac catccagcaa
    29341 gagctctttt ggttgttttc taaggagatt gcttgaagca agcgccataa cgagaaccac
    29401 tagaaccaag gcaaggacaa aaatgatgat aaagtctgat gtctgaatag aaatgtctag
    29461 gctcgacaag gtcttgctaa agccatctac ttctgcacca ccaccaaggt tagaggcttg
    29521 agccgcctta ctagcctgtt tggcaacacc tgaagtcaca ttggcaagga cagtgtttcc
    29581 aattgcacgg gcagtgtaat tagctaggaa gtaagcagaa actagagcag ggatagcaat
    29641 caagatagat tcggtgatga attgacccaa gatacttgcc tgcttgaggc cgatagagag
    29701 gagaattccc acttccttgc gacgggcgtt gatccaaagg ctgagcaaga gggcaaggag
    29761 gagaactgag aagctcaagc taccccagaa gaggaggttg gccatcttgt acataccaga
    29821 tatagattgc tcaagagctg ggtagttaga ggagctcttg acgagtgtgt agctcttcca
    29881 gttgatacca ctgatgccat tcaactcttt cataacatca tccaagttct tgtctgctgt
    29941 tacaaagaag gttgcgtccc cataaatggc tgtgtcttct gtgtatccat aaagttttgc
    30001 agcagtgtga atgtctgtaa tagctgtgtt ttcgtaaagt tcttgtgagt aggttactgc
    30061 tgacttatta tgaccatcaa agagtccctt gattgtcact tcaactgttt ccttggctcc
    30121 tttttcatta tctgcatcgt agatattaga gtccagttta accttgtccc ctactttcca
    30181 gccgtgtttg gctgccaagt ccttgtgcaa gaggatttta tccttgtcgt cgttggttaa
    30241 gtgctctcct tcgactagtt tataagaacc agagacaaac ttgtcttctt tagaggagtc
    30301 attgacacct gtaatcatca agctacttcc aaaacgtttg gcacgatcag cagtgagatt
    30361 cttcttggtt tctggcgttt caatcaggtc atatccagtc aaatctccga tagcgttgat
    30421 acgtttgaca taagactcaa tggccttgtt ttcggtgatt tttttgatgt cttcaccctt
    30481 gatattccca gcaccgcgag gcgttccttg gttgacgcga cgattgattt gcatggagaa
    30541 gctattggtg atatttttaa aggtctcctg agaagccttg gcagtagctc ccttgattga
    30601 caagccgacc aaactcaagc tcgccatgag gagaataatc aggaagatga caatcgattt
    30661 gaaaaacttc cttgtaacat aggcaaatgc gttgtgtaac atagattccc tttctagatt
    30721 ttgttttaat cattctatca aaataagctc aaattattta ctagtattgc gcgtttcagt
    30781 cagtttctta tcctttaatt caagtgtaat atctgacgct tgtgccactt ctttactgtg
    30841 agttacgaca atcacacatt tacctgtttt ctgggcaagt gatttgagta gttcgacaat
    30901 atctccagca gttttaggat ccagatttcc tgttggctca tcagctagaa taactggagc
    30961 ttctgagacc aaactgcgag caatggcaac acgttgctgt tgaccacctg ataactggag
    31021 aacattccgc ttgatctggc tttcatccaa accaagctca agaagtgtat tcttgcttgc
    31081 ctttttgttg accaatcgga tattttccag cggagaaaga taatctatca agttataatt
    31141 ttgaaagacc agggaaatat ggtgcatgcg atggtaagaa tagcccttct tacgaatatc
    31201 ctctccttga aaaaggatag aaccttcaac aggactatct agaccagcaa gtagggacaa
    31261 gagtgtggat tttcctgctc ctgactcccc aataatactg taaaattttc cgggttcaaa
    31321 attataatcg atctgatata ggactgcttc agcagtattc ttataacggt aggtaacatc
    31381 ttgtaattgt aataaagtca tgatttctcc ttcttaacta atagatgata aaatttcttt
    31441 cggtgatttt ctaaataaga ataggaaaca aagggctaca gataagcaac taagcagaac
    31501 tagaaaaaca taggattctg caaaagataa gatactagtt gataaactgc ttgctttggc
    31561 tagtgtatct tgtaagcttg cctgatctcc acttgctagt agagtttgga gtaggtaagt
    31621 tgtgattccg tttcctgcaa caaatgctgg aagcaaagct ccaagagata ccaaaactac
    31681 ctctaaacag aattgtagga agatcgagct cttgcctttt ccaagtgcaa gtaaaatccc
    31741 cacttcatag acccgttctc tcaaccagag agacaaaacc agaattaagg ctccagctcc
    31801 tgctatcaac atcccataaa ggaagatggt caggaaggtt tggaaagttg caactgagtc
    31861 tttgatttgt tcaaaagcct tgttttcctt ttcgacttgg tagccttgat tttccaaggc
    31921 caagttttct acctgcttca tgagtccgtc catttcctta ggattttcta catagaagcg
    31981 tgctgcactg acttgagctt cactattgcc caaaagggtt tggctacttt catagtctgt
    32041 aaagacttga ttttcactga agtcagaaga caagcctgtg aatttctctt gttttttacc
    32101 agaaaagatg ccgataatct caaactctac tgtttgtcct tttccagatt cagactgacc
    32161 agcatccaag ccaatcttgt catgaagcga aagaccgttc ttcttagcca attcttcgtg
    32221 gataaggatt ttcttggaat cccctttttg aaggtgtcgc ccttctttta gattgaaagc
    32281 cgaactggta aaggttacat ccttggatga atcctcaaga gccgttaagc taaccaagtt
    32341 attgtctgca gctgataaat catcacgctc cacgctctgc tcgccagtca ctgcttcctt
    32401 gtcttttagt tttgcgaccg tctcaagttc aggagagaca ttttccagcc ccttaatctt
    32461 gcttacagat gctaggtctg acaacttgaa tgtctgacca ttctctatct tcttaataga
    32521 aaaagatgta ttgagtgatt tataaagatt gctttctact gttttgttgg acttcatcag
    32581 agtcaaacag gctgaaattc cggccaataa gaccaataaa atcagaaata aaataaaact
    32641 tctcagtcgc tttctgctga cataagccca agatctttgg attggattca tttgtcacct
    32701 ccatatttgt aagactatta taaaacccaa atatgaaatg tttatgaaat acgaaaaaaa
    32761 aatatcgagt aggggataat ctctagcccc tctcacacca ccgtacgtgc cgttcggcat
    32821 acggcggttc aactaacttt taacgcatgt cgttcaaggt aataatccaa acacgaaacc
    32881 agtccacgtt ttccaaggac tggttttgat atagcacgtt taagtaccga cttctgagat
    32941 actatagtag attgaaacta gaataatata cctctacttc taaaatattg ttagaaatcg
    33001 atttgacttc cctgatcgat tcgtcctatt cttatttcat tttaatataa ttgatagtgg
    33061 tcgccccagc cagatacctt atctgctatc catttaggaa cccctaactt aagcaatccc
    33121 cataatcgtc tcgatttctt cttccattgc ttccagataa tcactcgtag gcgagtacgc
    33181 aagcgctcat ctatgctagt gactatactt ttcatattta taattcattc ctttcgtttc
    33241 actcaaggca caacacagaa tgaaaaagtg ttgtgatctt tattttgttt tataataata
    33301 gtgagaaagc ctatcactac tacaaatcac ggggaggtga ataagtgagt ggtacagcca
    33361 ctacctcgca tattttgtca catcatttaa cggtacataa taagttgtac catctgaata
    33421 agttgctaca atatcatttg catgctctcc ttcaccttta gcaaaggttg gagctcctgc
    33481 tggatgattt ttatttgcct ctttcaattt ttcaataatg gcattttttc tgtatctttt
    33541 atattatcag gatttttcac taagattttg tctggatatg tcggtttagc agaaacaatt
    33601 tttactgtta cttctttttt attcgaagca cttgtccagt ttccagcatt atctttagca
    33661 tttaatttta cagtaatttc tgaactagga acttcagtag caggttgatt atcaacatta
    33721 ttcaacttta atttcaaaag agctgttgca tcagacgttt tatcaatcgt tatatataat
    33781 gatgaattgt tattataaat agttccttca tatttagctg tttgtgagct acttgaaaca
    33841 gaactgaaat tatacccact acctccctga ttatcttcaa tgcttacgtc taaatgaact
    33901 tccccactat tatttggctt agcaacaact gttatagtaa aataacataa aatttgcata
    33961 aatagattag ggaaatcaaa gcagcttcta ggaatgtttt agcagtcaca gtgtactttc
    34021 ccagcatcaa gccactataa ctctgcacat aaaaatggag aagatggcaa tcctcttctc
    34081 caaatattaa cttctttaca aaccaactat agttgacaaa gaacctaaaa tcaattgata
    34141 acacaaggtc aggtcggtca actctttcaa ctgaagccct gtcaactctt cccatttatc
    34201 aatcttgtat tggagagaat tgcggtgcag atagagttgc tgggctgttt tagtgagaac
    34261 agcactattt tcccaaagag agagaatgat ttcctgaatc tgatcttgat ccaaaatcat
    34321 ctggtgtaga cattccttga ttggcttcaa gtccacgagt ctttctccca tactccaaag
    34381 atagagctga gaaaaagtat gaacaccttg gtgaccctga cgccaccatg tcttgaacaa
    34441 atcccgctca gctttgatta agtctgatag ggcttgatgt cccgtctgag accaaacctg
    34501 acccaacatg atagaaagac gaagtccaaa gtcatactca accgcttcaa tcgtatcact
    34561 taaaatatct cttacagaag tgtatttgtc ttgttgaagc acgaaaacat aatcctgagc
    34621 tccgacctgt agcactgtct gacaattcgg aaaaagagtc cgcatcatat ctagccaaga
    34681 agccagattt tcctgctgaa aataagaaag atggcaataa accaactgaa tctttttaaa
    34741 aacttgcggt gcctgtccct tgccctcaac cagataggaa taccaagggt ttagcgaacg
    34801 agcctgctcc tgctgggtca aaagggcaac caactgcttt tcacgctcgc tgagcccagc
    34861 ttcctccagc aaaatccact gctgagaagc taaagggagc gtgagatagc cctctttctc
    34921 tactggttgg tctgaaatcc gagcctcagg aaaccagtct tgtagttctt ttgccctcat
    34981 gttctagccc tccacttttt ggatgcacca tgaaaccaaa ctctcaagac gttccagatt
    35041 ctcagtcata tggagatagc ccataaccgc ttcaaatccc gtggacatac gataagtcac
    35101 gacatctgca tttttagcct ttgtgtggct attggtattg cggccacgtt tgtagatttc
    35161 ttcttctttt tccgttagga cctgctcctc caacatgaga gcaatcaggc gagcctgagc
    35221 cttggctgac acgtacttag ttgcttcttg atggagttta ttgggtttgg tcataccttt
    35281 gaggatgagg tgacggcgaa tatacataga atacaccgca tccccctcaa aggctagcgc
    35341 aatcccgtta atgagattga catcaatcac gtgtccacct cactccatcc ttggtatcaa
    35401 ggagcttaat tccttgagta accaattggt cacggatttg gtctgctgtc gcaaagtcac
    35461 gattggcacg cgcctcttgg cgtttttgaa tcaagtcttc aatctctgca tccaaaactt
    35521 cctcaacaaa gacaattcca aaaatttcta acatatctgc aagagcttgc ttgacacttg
    35581 catcatagtt ccctgagttg atccatttgg ccatttcaaa gacaactgtg ataccgttgg
    35641 cagcattaaa atcttcatcc atagctgcta caaacttatc tttaaagttt tgtaactctt
    35701 gggcatccac atttcctgta aatggttgtt cgtaagtatt cttgagatac ttgagattgg
    35761 tctcggcatc gcgaactgcc ttttccgtga agttgatagg cttacggtag tgctgggtcg
    35821 caaagaagaa acgaagtact tgcccatcaa gagttttaag ggcatcgtgt accgtaatga
    35881 agttacccaa ggacttagac attttgacat tgtcgatatt gacaaagcca ttgtgcatcc
    35941 agtagttagc aaaagccttg cctgttttag cttcagactg ggcaatttca ttggtgtggt
    36001 gtggaaactc taggtcagct ccaccaccgt ggatatcaat ggtatcacct aaaatctctg
    36061 tcgacatgac tgaacactca atatgccaac ccggacgtcc aggtccccaa ggactatccc
    36121 aagaaatctc acctggtttg gaagatttcc atagagcaaa gtctacagga ttttccttac
    36181 gagccgtttc ttcatcggta cgacctgaag cacctagctc caaatcttcc aaggttttat
    36241 tagccaattt agcatagttg tgggattttt ctacacggaa atagacatcc ccttgactct
    36301 cataggcaaa gcctttctcg atcaagtctt ccacaaaacg gatgatgtct gccataaact
    36361 ccactacacg cggatggcga gtcgcaggtt tcacgcccaa tgccgtcaca tcctcacgaa
    36421 aggcagcgat gtacttatcc gcaacctcct gaggtgtgat gccttcttcc ctggcacggt
    36481 tgataatctt atcatccaca tctgtaaaat tggaaatata ggcaacctta tacccacggt
    36541 actcaaaata gcgacgaatc gtatcaaaag ctaccgtcga acgggcgttt cccacgtgaa
    36601 tatagttgta cacggttggc ccacaaacat acatcttgat cttgccgtcc tcaatcggga
    36661 caaattctcg caaatcacga gacatggtgt catagatttt aatcataaat cataatcagg
    36721 aaagctaaaa tccaagaact gttagtttca tcactaaact aagagctcaa gtaaatttca
    36781 gtccgaatgt ctctacactt cggaatccct tgctcctttc tcattcagat aaaccacctg
    36841 tgtctgtttg acaaagccaa ttttttcata caaacgtttg gcacctacat tgctatcttc
    36901 cactgcaatc tgaaattcct tatcattttg ctcaattagt tggttgacaa gggattttgc
    36961 taagtagctt ccatagcctt tcccacgttc aggttctgat attgctaaac cgtagaagta
    37021 attcgtatcg ctcgataaat caaccgtgca agtcccaata acctgaccgt cttttaacaa
    37081 aatatataag cgactttctg gatccttcag agcttcagcg acatatctat ccacaacttc
    37141 tctcgattca tgttcccctg aaaatgcctg aaattttaac tggctaattt gctcctgata
    37201 cgaactatct gctaacaaaa cttcaagatt agaaagtttt gctaactgat atggtcttct
    37261 atccttacct aaccaggttt ctgtctcttc atcctcgatt agtccccagt tactggcaaa
    37321 gtcaggatga ttctctaaaa aaatacgttc tgtctgaaaa gtgactgacc gaatggggaa
    37381 agaagctgtt tctctctcaa aactagtaaa caatgcacgc gcaatcccct gacggcgatg
    37441 acctggatga accagtatcg tcacttctac atcttggtca tctgcataga cagttaataa
    37501 accaacaagt ttgccttttt cataataaag gaaaaaggcg ggcatgtttg ggtcaaaatt
    37561 aagcatgtta gagagatagg gatcgcgata ggtaccgtca tagttttggc aacagttaat
    37621 tacttttttc gcctcagata gctcctcttg gcttaacttg tttcttgctt gaatcatata
    37681 ggtatcctct acaaaccaga cgagctgtga ctggcatctt tagcctgctc gagtttattg
    37741 acataatact ctcgtttttc ttcgacttcg tgaatgacag gctcatcttt cttaccatga
    37801 agacggacaa tcttggccgg aataccgaca accgtcacat cactaggtac atctgctacg
    37861 acaactgctg cagcaccgac cttggcattt tcaccaattt ccacaggtcc gataacttgg
    37921 gcatgggctg atatgagggc tccctttcgt acagtcggat ggcgtttgcc acagtctttc
    37981 cctgttcccc caagagtcac tccgtgatag agaagaacgc ctttttcaac aatcgctgtc
    38041 tctccaatca ccagaccaga accatggtca ataaagacac ctgaatcaat ctgggctcct
    38101 ggatgaatct caatctgagt ccaaaagcgc caaaactgac tgtgcatacg agctaagagt
    38161 ttgaagctgt gcttccagag aaaatgcgag agacggtggg ccgccaaggc cttgacacct
    38221 ggataagtca gcaaaacctc caaagtggtg cgggccgctg gatcattttc ttttacgata
    38281 tcaatggttt cgcgccacca ccccatacat ttctcctttt cttattctga atcttttggt
    38341 gtttctgtaa attctttctt aggtttgtga tccttttgat gacgtgggcg gtgagggcgc
    38401 tcagactttt cacctttttc atcatgctca ggttttggcg gacgaggtag aagagccttc
    38461 atagaggcat cgatacggcc tttttcatca atcttgataa ccttaacatc aacttcatcc
    38521 ccgatttcta ccaaatcctc tacacgattg gtacgagtcc aagccatctc agagatatga
    38581 acaagggcat ctgtcttatc aaagaggtta acaaaggcac caaatttctc gatacgaacg
    38641 actttagcac ggtaaacttc atccactttg gcttcacgaa ccaaaccagc aataatttct
    38701 ttggcacggt taatagcatc ttggtcacta gagtagatag acacatttcc ttcttcgtct
    38761 atatcaatct taacacctgt ttcagcgata atcttgtcga tggtttctcc acccttaccg
    38821 atgacaatct taatcttgtc tacatcaatc ttgatcgtat caattttcgg agcagttgga
    38881 gccaattcta gacgaacttc tggaatggtt gcttcaatga catcaaggat ttcaaaacgc
    38941 gctttcttgg cttgagcaag agcctccgtc aagatttctg cagtaatccc ttgaatcttg
    39001 atatccattt gaagggctgt aatcccatca cgagtacctg caaccttgaa gtccatatct
    39061 ccaaagtgat cttccaaacc ttggatatct gtcaatactg tgtagttatt tccatctgag
    39121 ataagtccca tagcaatacc agctactggc gccttgattg gcacaccacc agccataagg
    39181 gcaagagttc ccgcacagat agaagcttga gatgaagaac cgtttgattc caaaacttct
    39241 gctactagac ggatagcgta tgggaattct tccaagcttg gcaagacttg agcaagagca
    39301 cgctcaccaa gggcaccgtg accgatttca cgacgacctg gcgcaccgta acg
//
LOCUS       DAVDHZ010000015        38735 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000015 DAVDHZ010000000
VERSION     DAVDHZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.015"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..318
                     /locus_tag="VUR46_000961"
     CDS             <1..318
                     /locus_tag="VUR46_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5456411.1"
                     /translation="HLYQLLLFHFQNKEPEKFFGFIEDNLKQVHPLFQTIFKTFLKDK
                     EKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVL
                     SQA"
     gene            complement(418..2040)
                     /gene="groL"
                     /locus_tag="VUR46_000962"
     CDS             complement(418..2040)
                     /gene="groL"
                     /locus_tag="VUR46_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET5456412.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGSATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2056..2340)
                     /gene="groES"
                     /locus_tag="VUR46_000963"
     CDS             complement(2056..2340)
                     /gene="groES"
                     /locus_tag="VUR46_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET5456413.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2610..3005)
                     /locus_tag="VUR46_000964"
     CDS             complement(2610..3005)
                     /locus_tag="VUR46_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET5456414.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRPRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3083..3844)
                     /locus_tag="VUR46_000965"
     CDS             complement(3083..3844)
                     /locus_tag="VUR46_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HET5456415.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTRQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(3886..4512)
                     /locus_tag="VUR46_000966"
     CDS             complement(3886..4512)
                     /locus_tag="VUR46_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET5456416.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVACLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMIPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4528..4845)
                     /locus_tag="VUR46_000967"
     CDS             complement(4528..4845)
                     /locus_tag="VUR46_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET5456417.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRDIYPALPEIEE
                     TNPEFTFIRMGRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4842..5141)
                     /locus_tag="VUR46_000968"
     CDS             complement(4842..5141)
                     /locus_tag="VUR46_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET5456418.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5421..5612)
                     /locus_tag="VUR46_000969"
     CDS             complement(5421..5612)
                     /locus_tag="VUR46_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET5456419.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5773..6447)
                     /locus_tag="VUR46_000970"
     CDS             complement(5773..6447)
                     /locus_tag="VUR46_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456420.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6453..6899)
                     /locus_tag="VUR46_000971"
     CDS             complement(6453..6899)
                     /locus_tag="VUR46_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456421.1"
                     /translation="MKLRIEIDGNLEETEIVIRTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRFKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7013..7516)
                     /locus_tag="VUR46_000972"
     CDS             complement(7013..7516)
                     /locus_tag="VUR46_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET5456422.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLDQQVGVYVFIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7513..7875)
                     /locus_tag="VUR46_000973"
     CDS             complement(7513..7875)
                     /locus_tag="VUR46_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET5456423.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKVESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGIRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7941..9800)
                     /locus_tag="VUR46_000974"
                     /pseudo
     CDS             complement(7941..9800)
                     /locus_tag="VUR46_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9839..10288)
                     /locus_tag="VUR46_000975"
     CDS             complement(9839..10288)
                     /locus_tag="VUR46_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5456424.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQAVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRMVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(10412..11128)
                     /locus_tag="VUR46_000976"
     CDS             complement(10412..11128)
                     /locus_tag="VUR46_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5456425.1"
                     /translation="MGRKWSNIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12009..13424)
                     /gene="ply"
                     /locus_tag="VUR46_000977"
     CDS             complement(12009..13424)
                     /gene="ply"
                     /locus_tag="VUR46_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET5456426.1"
                     /translation="MANKAVNDFILAMDYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TAKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKIEND"
     gene            complement(13435..13767)
                     /locus_tag="VUR46_000978"
     CDS             complement(13435..13767)
                     /locus_tag="VUR46_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456427.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEVLDHLVQPQLISLNKSEF
                     MQLNSGTY"
     gene            complement(13838..14446)
                     /locus_tag="VUR46_000979"
     CDS             complement(13838..14446)
                     /locus_tag="VUR46_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456428.1"
                     /translation="MFQSSYLLPLLWLKKEADKEKMSATQCQIFFFYYQLFELLFARE
                     SDLKDLCLGGQGFYFSQLEKDLLSGVSRFLTNLEGKGTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQAVERLETPLLLSFQDRQDLMWIYQSALEKDYSVKVIGDKHFVL
                     KRQDATKLTGRQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14459..14917)
                     /locus_tag="VUR46_000980"
     CDS             complement(14459..14917)
                     /locus_tag="VUR46_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET5456429.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKEHWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASAEAPGKKE"
     gene            15042..15441
                     /locus_tag="VUR46_000981"
                     /pseudo
     CDS             15042..15441
                     /locus_tag="VUR46_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15626..16564)
                     /locus_tag="VUR46_000982"
                     /pseudo
     CDS             complement(15626..16564)
                     /locus_tag="VUR46_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17100..17360)
                     /locus_tag="VUR46_000983"
     CDS             complement(17100..17360)
                     /locus_tag="VUR46_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456430.1"
                     /translation="MRERSATGAQGLSKFIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTIPQNDDISLDQNEIFQILKNFLDG"
     gene            complement(17482..17961)
                     /locus_tag="VUR46_000984"
                     /pseudo
     CDS             complement(17482..17961)
                     /locus_tag="VUR46_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17951..18946)
                     /locus_tag="VUR46_000985"
     CDS             complement(17951..18946)
                     /locus_tag="VUR46_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456431.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELALTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMNVVLVFSKLSDSEKKQLLQARIPFVDFKG
                     NLFFPTLGLVLNADDTEVPKELTPSEQLTWIAFLLTKDQKVVDVELLSRVTGLPNSTI
                     YRCLRTFKALDWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGTYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHALEGKVLEIWKYCPF
                     ISEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEVLENMILQYLGDDDAS"
     gene            complement(19355..19726)
                     /locus_tag="VUR46_000986"
     CDS             complement(19355..19726)
                     /locus_tag="VUR46_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456432.1"
                     /translation="MTEQLLEKLYSGKIVIPQEVYDEINIPTIPHLKSRIDQLVTKGS
                     AEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLAKKHNGILGSNNLRDVKPY
                     VEEFSLEHMTTGDILVEAFKA"
     gene            complement(19736..20119)
                     /locus_tag="VUR46_000987"
     CDS             complement(19736..20119)
                     /locus_tag="VUR46_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456433.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKETVLG"
     gene            complement(20333..20506)
                     /locus_tag="VUR46_000988"
                     /pseudo
     CDS             complement(20333..20506)
                     /locus_tag="VUR46_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055999.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(20871..21827)
                     /gene="lytA"
                     /locus_tag="VUR46_000989"
     CDS             complement(20871..21827)
                     /gene="lytA"
                     /locus_tag="VUR46_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET5456434.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKVNDTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(22203..23573)
                     /locus_tag="VUR46_000990"
                     /pseudo
     CDS             complement(22203..23573)
                     /locus_tag="VUR46_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
     gene            complement(23898..25064)
                     /gene="recA"
                     /locus_tag="VUR46_000991"
     CDS             complement(23898..25064)
                     /gene="recA"
                     /locus_tag="VUR46_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET5456435.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEASEQDIENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(25119..26375)
                     /locus_tag="VUR46_000992"
     CDS             complement(25119..26375)
                     /locus_tag="VUR46_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET5456436.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGVSLTGVAGPDSLEGHPVGTVFIGLAQEQETEVINVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(26459..27475)
                     /locus_tag="VUR46_000993"
     CDS             complement(26459..27475)
                     /locus_tag="VUR46_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET5456437.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGVELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRVHMLEMQNILRRSLGQEEVTQLETNVVLFEDLFGRAPVG
                     DEDN"
     gene            complement(27483..28001)
                     /locus_tag="VUR46_000994"
     CDS             complement(27483..28001)
                     /locus_tag="VUR46_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456438.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(27991..28434)
                     /gene="tsaE"
                     /locus_tag="VUR46_000995"
     CDS             complement(27991..28434)
                     /gene="tsaE"
                     /locus_tag="VUR46_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET5456439.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDTYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(28520..29140)
                     /locus_tag="VUR46_000996"
     CDS             complement(28520..29140)
                     /locus_tag="VUR46_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456440.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIATLIFF"
     gene            complement(29744..29944)
                     /gene="tnpA"
                     /locus_tag="VUR46_000997"
                     /pseudo
     CDS             complement(29744..29944)
                     /gene="tnpA"
                     /locus_tag="VUR46_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(30048..30271)
                     /gene="tnpA"
                     /locus_tag="VUR46_000998"
                     /pseudo
     CDS             complement(30048..30271)
                     /gene="tnpA"
                     /locus_tag="VUR46_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(30505..30918)
                     /gene="ndk"
                     /locus_tag="VUR46_000999"
     CDS             complement(30505..30918)
                     /gene="ndk"
                     /locus_tag="VUR46_000999"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET5456441.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGTKVIEIWRTMMGATRPEEALPGTI
                     RGDFAKAAEENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(31019..34696)
                     /gene="rpoC"
                     /locus_tag="VUR46_001000"
     CDS             complement(31019..34696)
                     /gene="rpoC"
                     /locus_tag="VUR46_001000"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET5456442.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKVL
                     FNDIMPEGLPYLQEPNNGNLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYQHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIADQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(34730..38341)
                     /locus_tag="VUR46_001001"
     CDS             complement(34730..38341)
                     /locus_tag="VUR46_001001"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET5456443.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHA
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVVMSERLVKDDIYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEDAEKATKAEATEEAAEQE"
BASE COUNT        11240 a         8770 c         6984 g        11741 t
ORIGIN      
        1 catctctatc aactcttgct gtttcacttt cagaataagg aaccggagaa atttttcgga
       61 ttcattgagg acaatctaaa gcaggttcat cctctttttc agactatctt taaaaccttc
      121 ctcaaagata aagagaagat tgtcaacgcc cttcaactac actattctaa tgccaaactg
      181 gaagcaacca ataatctcat caaacttatc aagcgcaatg cctttggttt tcggaacttt
      241 gaaaacttca aaaaacggat ttttatcgcc ctgaatatca aaaaagaaag gacgaaattt
      301 gtcctttctc aagcttagct ttttttcaac ccactacagt tgacaaagag cctataaaaa
      361 gaagggttag tcattccctc cttttgtgtt ttttataagt tgttttctat agaaagctta
      421 catcatcccg cccatcatac ttggatccat tgctggagct ggggctactg gttctggttt
      481 attggctacg actgcttctg ttgtcaaaat caagctggct acagatgctg cattttgtag
      541 ggctgaacga ctcactttaa ctggatcaat gataccttga tcaatcatgt taacccactc
      601 gccagttgct gcgttgaatc ctataccaag ctcagcattt ttcaaacgat cgataacgat
      661 agatccttca aatcctgcat tgtgagcaat ttgacgaacg ggttcttcca aagcacggag
      721 aacaatatta cgtcctgttg cttcatctcc tgtcaattcc aaggtagcaa cagctggaat
      781 cacattggca agagctgttc caccacctgc aacaatacct tcttcaacag ctgcacgagt
      841 agcgttgagg gcatcttcaa tgcggagttt catttctttc aactcagttt cagttgcgga
      901 tccgacctta ataaccgcta caccacctga caatttggcc aagcgttctt gcaatttttc
      961 acggtcaaat tcagaagttg tagtttcgat ttgagacttg ataaccgcaa cacggtgaga
     1021 aatcgcttca ggatttcctg caccttctac aataaccgtg ctatctttgt ccacggtcac
     1081 tctcgctgct tgaccaagag cttcaattgt cgcatctttc aactcaagac caaggtcttc
     1141 tgtgataact gttccgcctg ttaagatggc gatatcttca agcatagctt tgcgacggtc
     1201 accaaaacca ggtgccttga ctgctactac gttgaaggtt ccacgaatct tgttcaaaac
     1261 aagagttgga agagcctcgc catccacatc atccgcaata atcaagagtg gacgattgct
     1321 ttggagaatg ctttccaaaa gtggcaagat ttcttggata ttggaaattt tcttgtctgt
     1381 aatcaaaatg tacggatttt caaggtcagc caccattttt tcgctatctg tcaccatgta
     1441 ctgtgaaagg taaccacggt caaactgcat tccttctacg acttcaagct ctgtttccat
     1501 accacgtgac tcttcgatgg tgatgacacc gtctttgcca actttttcca ttgcttcaga
     1561 gatgtactca ccaacttttt cagaacgaga agatacggct gcaacttgag cgatagcttc
     1621 tttattggca acagggatgg cgttgttttt caaagcttca actgctgcgg caactgctgt
     1681 ttcaatccca cgacgaatac cgattggatt tgcacctgct gtgacgtttt tgattccttc
     1741 acggacgata gcttgggtca agactgttgc agtcgtagtc ccgtcacctg cgatatcatt
     1801 ggttttagaa gctacttctg atactaactt agcacccata ttttcaaaat ggtcttccaa
     1861 ttcgatttct ttggcaatgg tcacaccgtc attggtaatc aagggtgaac cgaatgactt
     1921 ttcaagaacg acattgcgac cttttggtcc caaggttact ttaacagtgt ctgcaaggat
     1981 atcgacacca cgaaccatgg ctgaacgggc atctgatgaa aatttaattt cttttgacat
     2041 acttactttc tccttctatt cctcaatgat tgccaaaatg ttagcttcgc ctacgatgat
     2101 gtacttttca tcgccatctt tgacatcaag acctgcgtgg gcttcaacta agacacgatc
     2161 tccagtttta acacttggag caaccaagtc accgttcaag gtacgaacac cttgtccagt
     2221 agccacaact tgagctgttt tggttttttc ttgggctgat cctgcaagga caaagccccc
     2281 aacggtttgt tctttttctt ctatttttaa gaccacacgg tcccctaatg gtttcaacat
     2341 ctgatttcct ccataatgag atagatatta ttagcactct ttgaacttga gtgctaattc
     2401 ataattctat tgtatcactt ggtcagaaat agtcaagaaa aaagtctgac tttctcaaga
     2461 taaaaagcct gagaccaact cagacttttt aatgtttata ctcaataaaa atcaaagagc
     2521 aaactaggaa gctagccgca ggttgctcaa agcattgctt tgaggttgtg gataaagcta
     2581 acgtggtttg aagagatttt cgaagagtat taaaatggca attcttcctc ttccaagacc
     2641 aaatctgcca aatcttggcc tgcattattt tcacgcatgg cacgttgagc acgactttct
     2701 aagagttgga atcctgtcac aaggacttcg gttacatagt tcatctgacc atttttctca
     2761 aagcgacggg gacgcaattc tccatcaacg gaaatgagac tacctttggt tgcgtagctt
     2821 gccaaagttt ctgctagtct gccccatagg accatattga caaaatcagc ttcacgttca
     2881 ccgttttggt ctttgtaacg acggttgaca gcgatagttg ctcgcgctac cgacttgtca
     2941 ttgttggttt tgtgcaattc tggtgtagac gttaaacgcc caatcatgat aactttatta
     3001 tacatatttt cttcctccta cttatctatt cgtaggaaat caaaaaaagt tacagaaatt
     3061 tgtaactttt cgaggaaatt tcttattttt tatgaatcat gaaacctgtc gcctgttgat
     3121 tagccataat ggtcatatct gtaatctgaa cacggcgagg ctgtctggtc acatagacta
     3181 ctgtgtctgc aatatcctga gcttgcaagg cttctattcc ttggtaaacg gacgcagccc
     3241 gctctttatc accatgaaaa cgaacagttg agaaatctgt ttcgacaatc ccaggctgaa
     3301 tggttgtcac cttgatatcc gttgcgatgg tatcaattcg cagtccatct gaaaaggtct
     3361 taactgccgc cttggtggct gagtaaacag ctgcaccagc ataggcataa attcctgcgg
     3421 ttgaccccat attgataata tgaccttgat tggcttttac cattgctggc aagaaacagc
     3481 gagtgactgc catcaaacct ttgacattgg tatccaacat ggtcagcata tccaactctt
     3541 catagtcttg atagggagct aagccaagag ccagtccggc gttgttgacc aagatatcaa
     3601 tcctccctat cgtttctaga atatcagagc aaacagtctt caccatgacc atatccgtca
     3661 catctagtgg aaaagtccaa actgtttgat ttggaaaagt ttctgcaaac tccgccttaa
     3721 gagcttctag tctgtctatc cgtcgtcctg ttagaacgac atcctcaccc tgctctagat
     3781 aagcacgcgc aatcgcttca ccgattcctg atgtcgctcc tgtaatcaca acattttttg
     3841 ccatcttatt tccttctagc tggtctatca gatattaaca acttcttagg cagtccagtg
     3901 tttagctgag tcaaatggtg ttccgacaac ttggtcttct gataattcaa gcaccccacg
     3961 tttttgtgga gcatttggca gatgcaattc acgaggactg cacatcatac caaaactctt
     4021 ttcaccacga agttcacctg ggaaaatgag attccctttt ggtatcatag ctccaggaag
     4081 cgcgacaatg gttttcaacc ccacacgcgc attgggagct cctgcaacaa tttgtacagt
     4141 cttatcactt gcgactgcaa cttggcagat gttgaggtgg tcactatctg gatgggctac
     4201 catctcaaca atttcaccaa caacaaactt aggttccttg tcattgacaa tttcttctgt
     4261 aaaaccttcc gcctgtaatt cttggttcaa acaagcgact tgctcatctg ataaaaagac
     4321 ttgacctcgc tctgcaattt caaacaagct cgaaacctca aaaatgttcc aagctactgt
     4381 ttccccattt tctttgagga aaacacgggc taccttgcct ttgcgttcca cattcagttt
     4441 ggcatctccg ctatttttca cgatgaccat aaggacatca ccgacatgtt ctttgttata
     4501 tgtaaaaatc attgtttcct ttttctccta tttcaatcct gctaaaaaat cgttaatttg
     4561 ctccttactt ttacggtcgc gattgacaaa acgaccgatt tccttgtcct tttctagaac
     4621 aacaaggcta ggaattccgt aaacatccca gagtttggcc aaatccatat actgatctcg
     4681 gcccattcga ataaaggtga actctggatt ggtctcctca atctctggta aggcaggata
     4741 aatatcacga caatcgccac accagtctgc cacaaaaagg aagaccttct tgcccgcttt
     4801 ttccactaaa gatgctaatt cttctaaact tgctggctgt atcataagac ttcctcctca
     4861 tagactaggt cttcattttc atagacaaag gtataatgac ggccatcctc aaaaatgacg
     4921 ccaccaacca agctctccag actgctttcg taaacttgaa cataaagggt cgcaatttcc
     4981 cccatgtcgg aaaaatggtc tcgcacaatc tctgtcaact cttcctgagt cttcatgagc
     5041 ttacggtcat ctgcaacttt tttcgtagca agagcaaggc ttccgatacc tagcagagcc
     5101 aagcctgcca tccacatttt tttagctttc ataccattca ttttaacaca aaaaaggctt
     5161 caagacaaat gaggaagcag cagaaaagca agtaaaaagc ctcttccttt aaggaaaagg
     5221 acttcttatg ctaagagcaa actagaaagc tagccgcagg ctgctcaaaa cactgttttg
     5281 aggttgtgga tgaagctgac gtggtttgaa gagattttca aagagtatta ttcttattgc
     5341 caggcaccta agttgccaac gtagtaacca tcaggtgtgt aggtattgcg aagcatctta
     5401 cctgatgaag ccagataata ctacttgcca ttgtctttga cccaatcatt cgcaatcatg
     5461 gaaccagaag aacttacata ataccattct cccttgtcat aaacccaagt actgactttc
     5521 atggttcctg agcaattaaa ggcaaaaaaa ctgtccaata tcattcgttt tttaaaagca
     5581 tttgacacta catcatctac gctgtagtac atagatacat caaacgtaaa agccaaaata
     5641 tcgaaaaata tacaactttt aaaggcagca tttcattttt taaagtctaa caaccataga
     5701 actgaaatca gagcaaggca tcaatttcct actcttagta cgtctatttt gatggttgaa
     5761 gtgaagattt ttttatttaa cgtagacaat ttccaacttc ccaaaagcca catctccacg
     5821 gatagtcaag gttttgctgg ttggggctac aggagcgtca gccttagctg caccaaagga
     5881 ggtttctact ttcaaatcta cacgccagtg ttgtggaaca tagacggttg catttccgaa
     5941 ggccacttca atatttaaag ttgcaaaatc acctagcatc tctgcattat catagtagat
     6001 tttagcatcc ccaaaagcga cttccacttg gtcatctacg agatcttgat cttgcttata
     6061 gaaggtcccg ctaccaaaag cgacttcctt atccgtgacg actgtttttt tcccattgta
     6121 ccaccatttt ttttcattcc agaacttact tgaatgcgtc agataaccaa caccaagtac
     6181 caccaagatg ctagcccaaa taagagaatg attggtaact ggtaacaagt cataagcgta
     6241 atttgcaatg atgagcgcca gtaaacctgt aaaaactgcc gaagtgagat gacgtctaag
     6301 gatggactca atggacttat aagcaaaaaa aacaatacct agtaaaggcc atattttacc
     6361 atccaaagaa ggaattccaa aattcccttg cagcaagatc caagctgcta aaaccaataa
     6421 aacaatacca aatgctttct ttttcatgtt ttttacctca tgtttcttag attttctttt
     6481 aggagggatt ggtaatgccg tgagacatga acctccttgt gcgtctgata gaaggaaatg
     6541 gtgcccgttc ctgaaaagga cttgtccact gagtaaatct gacggatgtt tgcgatcgtt
     6601 gacttggaaa ctcgattaaa atagcgaggc aagatagatt ccaactcata gagcttgaag
     6661 cgaacctcat aagcttcctt ctggttatga gcgtagatct tgctcccttc tgtttcaaag
     6721 aagagaattt ctgacaggtc tagataatat tcacctgtcc ccttgtaaaa agtcaacctc
     6781 ggagcctttg actcttgcaa gagccgttgc aagtctgcaa tttcatctgt caaagtgggg
     6841 gtcctgatga caatttcagt ctcctctaaa ttaccgtcaa tctcaattcg taacttcatc
     6901 acatctcctt tctgactcta ctatatcaaa gctaagttag gaatacaagg gcaaaaaagc
     6961 aagtggtcaa tttgaagcag taagtggttg taggactagc ttaacttaca tgtcagaata
     7021 ggaagaaaag gaatccccac accagaccac aagcatagcc aaccaagaca tccttgggat
     7081 aatgaacacc ccctaaaacc ctcaccaacc ccagcaaagc tgaaaagatc aagcatacta
     7141 agccaatagg tagactagca tgcagacagg ccatggagat gatagttgcc gaaaagacat
     7201 ggcgactggg catcgaccgt cccgaactat ccttatcaag aaggggacag atatcccaag
     7261 tttcataagg tctcgggtga ttgattttct tacgaaacag ggacaaggcc acaaaacctg
     7321 atgcaggaat aaacacataa accccaactt gctgatcaag tcctagttgc aggtaagtgg
     7381 tgactagcaa gatcagatag accaggggca tggcgactgt catcaaacga ttgaaactgc
     7441 gtaataggaa taaaagaatt ggacgactag ttagtctgga gctgatattt cgataccatt
     7501 cttgataatt tttcatttat gcttctcata cttttctaga acttgttgag atgttttccc
     7561 cttggcaagc caatccacta gcttgtccaa gcgacgtatt tcctgcatca gaggatcatc
     7621 aatttcctca atacggatac cgcaaatctt ccctgtaatt gcaattcgtt cagggacata
     7681 atatggtgct tgtcgaaaaa aatctccgta agtaacatcc ctatccagac aagcaagaac
     7741 gtcactcact tcataccctg tcaaccaact ggtcacttgg tgaactgact ctacctttcc
     7801 accctttcgc tcaacttttg caatcaaggc taagtagaca gcagcaaatt tcatattgta
     7861 taatttctga ctcatacttc tctctttcta tgtgtactag tataaatcag aaaaagaagg
     7921 ccgtcaagcc ttcttttgat ttattcttct gcttcatctt ctgtaaattg actattgtac
     7981 aagtcagcgt agaagccacc ttgcgccatc agttcctcat agttgccttg ctcgatgata
     8041 tttccatctt tcatgaccaa gatcaaatct gcattttgga tggttgacaa gcggtgggca
     8101 atgacaaagg atgtgcgtcc ttccatcaaa cggtccatgg ctttttggat caattcctct
     8161 gtccgtgtgt caacagaaga agtcgcctca tccaaaatca aaagcggtcc atccttaaga
     8221 agggcacgag caatagtcaa tagttgtttt tgtcctacag acaaggtcac ggtgtcatcc
     8281 aagatggtat catagccatc tggcaaggtc ataataaagt ggtgaattcc cacagcctta
     8341 ctagcttcca tcattcgttc atcactaatc cctatttgat tatagatgag attgtcccga
     8401 atagttcctt caaagagcca ggtatcctgc aagaccattg aaaaagcatc atgcacttct
     8461 gaacgcgtca tagccttggt atccacacca tcaatgcgaa tacttccctt atcaatctca
     8521 tagaatttca tcaaaagatt gacaatggtt gtcttaccag ccccagtcgg cccaacaatg
     8581 gcaacctttt gaccagcatg agctgtcgca gagaagtcat agtcttgaac attgacaccg
     8641 tccaccagaa tttctcctgc tgacacgtcg tagaaacgtg gaatcagatt gaccagagtt
     8701 gatttaccag aacctgttga cccaataaag gccactgttt gaccagtttc tgctttaaag
     8761 ctaacatgtt caataactgc ctccgaattt gccgcatagc ggaaggtcac atccttaaac
     8821 tcgacctgac ctttgaagtt ttcatcagcc agctgcactt gaacagagtt ttggatagaa
     8881 gaatgcaaat ctaaaacttg attaatccgc ttagcagaga ccatagttcg gggaagaacg
     8941 atgaagagtg ctcccatgag aaggaagccc atgacaacct acatggcata agacatgaaa
     9001 acaatcatgt cactaaagag aggcagacgc gctatcggag caacgtcgtt aatcacatag
     9061 gccccaatcc agtaaatcgc tacactcaaa ccacttgaaa tccccatcat gataggattc
     9121 aaaatagcca taagacggtt gacaaacaaa ttcaaacggg tcaattcatc atttactgct
     9181 gcaaattttt cattttgata atcctctgca ttgtagacac gaacgacacg aatacctgtt
     9241 aaactctcac gagtgatact gttcagttta tctgtcagcc cctgaatcaa ggactgtttt
     9301 gaaaaggcta gcgtcatcaa aacggtcgtc atcaggacgt tgacaatcac tgccacaagt
     9361 acggcccaga gtcagtattc tgaatgacct aaaatcttcc caatagccca gatagccata
     9421 attgaaccac gcgttaccac ttgcaagccc atagtaatca acatttgaac ttgagtaatg
     9481 tcattggtag tacgcgtcaa gaggctagga attgaaaatt tcttaatctt tgtctgcgag
     9541 taatccaaaa ctcggttaaa aatatcactt ctcagcctac taatataaga agccgccact
     9601 cgggatgcaa aaaatccaac tgcaactacg gacaagaagg caagaaaggg cattcccatc
     9661 atcatgcttg ccggctgcca caactcatct aaattagttc cttgactacc tagcaaatcc
     9721 gtaattttcg agatataggt cggcacttcc aactctagat agaccgaaaa gcaagtaaag
     9781 agaatggcta gtaaaatcat cccccattct tttctactaa ttcttttggc taatttcttt
     9841 attctctcct cctattccct tgatattttg cctgtagttg accgagaact ttctcaaaaa
     9901 tcagtaattc atcttcatca atgtcttcca tcaactgctt gtctatgcgt tcaaaaaaag
     9961 ccttaacctg ttgcatctga gaacgtgctt tgtccgtcag acgaacaaac ttagcccgct
    10021 tatcaacagg actcgcctcc aattccacca aaccattttg caccatacgc ttaaccagat
    10081 tactagcaac agacttggta atattgagtt cctgctcgat atctttaatc aagaccaagt
    10141 cttggttttt ctcgcgatta tccaaaaaac gcacagcctg accttgcggc ccacccataa
    10201 attcaatgcc gcaacgtttg gcttcctttt gcaccatcag gtgaatttga tgaccaaaac
    10261 gcttaaagac taacatcggt ttatccataa tctccccctt ctaaataaaa atagttctct
    10321 ggagaataat taaatttcta tgagaactat tttcttgatt aaaaaaatcc caagtgattt
    10381 tctcacttag gatcatgttc tataggttaa attaaaaccc atctacgttc gtataaatct
    10441 tttggacgtc ttcgtcgtct tcaagaacgc tgtaaagttt ttcaaaggtt tcaaggtctt
    10501 cgcctgacaa ttccacttct gactgaggaa tcatttccaa ttcagtcact tggaattctt
    10561 caataccaga ctcacggagg gcaacgatag ccttgtgaag gtcagttggc gctgtgtaaa
    10621 ctgtgattgt accttcttgt gcttctacgt catccacatc cacatccgct tcgagcaatt
    10681 gctcaaagac tgcgtccgca tcttcacctc caaatacaat aacacctttg ttgtcaaaga
    10741 ggtaagaaac agaacctgaa gcgcccatgt ttccgccgtt tttaccaaag gctgcacgga
    10801 cattggctgc tgtacggtta acgttagaag tcaaagtatc cacaattagc atagagccat
    10861 ttggcccaaa accttcgtaa cgtccttctg taaaggtttc gtctgtgttt cctttggctt
    10921 tatcaatcgc tttatcgata acgtgttttg gcacttgggc ttgtttagca cggtcgataa
    10981 cgaatttcaa agctgagttt gattctggat ctggatcacc ttttttagct gctacataga
    11041 tttctacacc aaattttgca tatactttag agttggctcc atctttagcc gttttcttgg
    11101 ctacgatatt ggaccattta cgtcccatta ggaatctcct tttttcacat tttaatcttt
    11161 cttattataa cacaagtttt tttgattttc actagaggaa atgggtttta ttagcaaatc
    11221 aagctaggat agtactttac ctgctaagat ggtcttgcct ttctatcttt atcaacagac
    11281 actcatccac attcaaaaaa caaactagac cattatctgc aaatagaaag tttcagccaa
    11341 gtttgacaaa gtcagctcaa attactgttt gaagtttgta gatataagcg acaaaaacaa
    11401 tcatactgca ccttttgttg acagtctact ccagacatat catagttcaa gtaaatactt
    11461 tgaaatccaa cagttcttat aggtgctatt gtattctaag aaatcaatag aagagtttct
    11521 aagcaaatct ctaatactca ataaaaatca aagagcaaac tagaaagcta gccgcaggtt
    11581 gctcaaaaca ctgttttgaa gttgcggata gggctgacat ggtttgaaga gattttcgaa
    11641 gagtataatt tacgtgttcc caagatggag aagttagact agtacactgg cacttctaaa
    11701 ccattgctag caattgattt gttcatattt aatttcattt tttccataaa tgggtattag
    11761 atataaacag caaaatattt ccgatacgtg tcattcttga atttccaatc atctaaaaca
    11821 agtaaaggat aatcaatccc ctgtatatca aggaattggc tacccttttt acttttttac
    11881 acattctgtt tgatagattc attttaacat cacgagcata ctccaatgga aatcgctagg
    11941 caagagataa actttcagat atccgcagag agatcatcgc ctctttttgt cgcaagcatt
    12001 ctcctctcct aatcattttc tatcttatcc tctacctgag gataaagagt cgttccccaa
    12061 atagaaatcg tccgcttacg cactagtggc aaatcggttt tttcataaac cgtacgccac
    12121 cattcccagg caagcccggt acactctcta attttgacag agagattacg aacattccct
    12181 tttaaaggaa tactagtggt aaagtgagcc gtcaaatcct gcccatttct gtcccaagcc
    12241 ttagcagtta agacttcctt accttgatga tcataggata attcatccca agtaatataa
    12301 tattgggcaa cataggcacc actatgatcc agcagtaaat ctccgtttct gtaagctgta
    12361 accttagtct caacatagtc tgtactgttt tgaaaggtcg caactacatt gtcacgtaaa
    12421 aaagaagttg tataggaaat cggcaagcct ggatgatctg ctgtaaagcg actgccttct
    12481 tgaatcaagt cctctaccat atccaccttg cctgttacaa ctcgggcacc cgaactcggg
    12541 tctcccccta aaataaccgc cttcacttct gtattgtcca aaatctgctt ccactctgtc
    12601 tgaggagcta ccttgactcc ttttatcaaa gcttcaaaag cagcctctac ttcatcactc
    12661 ttactcgtgg tttccaactt gagatagact tggcgcccat aagcaacact cgaaatatag
    12721 accaaaggac gctctgcaga aattcctctc tgctttaaat cctctaccgt tacagtatct
    12781 tgaaacacat ctcctggatt tttaacagca tctacgctga ctgtataata aatctgctta
    12841 aaattaacaa tctgaatctg cttttcgcct gaatggacag agttaaaatc aatatcaaga
    12901 gaattccctg tcttttcaaa gtcagaacca aacttgacct tgagttgttc catgctgtga
    12961 gccgtgattt tttcatactg cattctagct gggacattat tgacctgacc ataatcttga
    13021 tgccacttag ccaacaaatc gtttaccgct ccgcgaacac ttgaattgct ggggtcttcc
    13081 acttggagaa agctatcgct acttgccaaa ccaggcaaat caatactata agtcatcgga
    13141 gcacgatcga ccgcaagaag agtgggatta ttctctaaca aggtctcatc cactacgaga
    13201 agtgctccag gatagaggcg actgtcgttg gtagctgtta cagaaatatc acttgtattt
    13261 gtcgacaagc tccgcttctt tctttcgata acaacaaact catcgggtag ctgattaccc
    13321 tctttgatga aacgattttc aatactttct ccctgatggg tcaagagttt ctttttgtcg
    13381 taatccatag ctagtataaa gtcatttact gctttatttg ccatcttcta cctcctaata
    13441 agttcctgaa ttgagttgca taaactcaga cttgttcagc gaaatcagct gtggttggac
    13501 taggtgatcc aaaacttcct cgtacaattc ttctgagaca ttgcgtcgcc gtctggctag
    13561 ataagaagtc ggaatgaccg tattatccaa cataaatacc ttatctaagt caatcaaggt
    13621 tggtcttgta aaaggattac gagctagatc cggctcttct atcataaagt tcttgaccaa
    13681 acgtctggtc aagagagctg gtttgaaggt ctgattttta accaactctt tgtttttagt
    13741 catgctgttg tcaatacaga tatacatatg attcttcaca gccaaatcgc tactaatact
    13801 tggaaaaggc aaataaagag ctacaacatc tcctctctta atcaagcaag agcaccccct
    13861 tttctcctaa tgtaacatag acaggattga ccaagtcttc tgattgactc agaatttcca
    13921 aagtttgagt ttggcgccct gtcaatttag tagcatcttg tctcttcaat acaaaatgct
    13981 tgtcgccaat caccttgaca ctataatctt tctccaaagc tgattggtaa atccacatca
    14041 gatcttgtct gtcttgaaaa ctcaagagta agggcgtttc aagtctctct acagcctgat
    14101 aaaaatcaaa aacaggagct aattcctgcc aatctgactg gctagttgtc aaggctagaa
    14161 aaagggcttt gcgagctgat acttcttggt tagccttgag agtccctttt ccctccaagt
    14221 ttgttagaaa tcgggaaact ccagaaagca aatctttctc taactgcgag aaataaaaac
    14281 cttgccctcc cagacacaag tctttcaagt cgctttctct agcaaataag agttcaaaca
    14341 gttgataata aaagaaaaat atctggcact gggtcgcgct catcttttcc ttatcggctt
    14401 ctttttttaa ccagagcaag ggcaataggt agctggattg aaacatttcc tccacctcct
    14461 actctttttt ccctggagct tctgcactag ctgccacttc ttttgactgg atactttccc
    14521 actggttgat ttcctctgag ataagacctt cgcatgtctt gacaaatagg gcaaaagcct
    14581 tggtctttcc tgcatatttc tccgtttggc attgatagag gaatttttct ttctccagga
    14641 gttgcgcagt cttttggtaa gaaatccagt gttccttggc attatacaaa ttgataatcc
    14701 cctcacacag caagccgaga ctggataagg caaccgaaat caaacggtag cgatcacctg
    14761 gcataggaat agcacaaaag acagctatga ggaaacctgc cacgatttct gttattttta
    14821 ataccttata gcgtctacga tgttgaacgc ttttctttaa aaaatgagct atctgtacgt
    14881 ctaatcgctc tgtcaggtac atttcttctg gcgtcatgtt cgtaactcct ttcatttact
    14941 ttgataatca tagtataaca tatttgaata tcaaagtata gtaaaaactg gactataact
    15001 tattagactt cctgcgaaac aaaatatggt atagtagttc tatgcattat gaagcaagta
    15061 aacaactaac tgatgcacga tttaagcgtc ttgttggtgt tcagcgcacg acttttgaag
    15121 agatgttagc tgtattaaaa acagcttatc aaaaaagtcg gacaagctgg taaaatcttg
    15181 gctgacagtg gttatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa
    15241 tccagcaaac tcaagccgct aacagctgaa gataaagcct ataaccatgc actatctaag
    15301 gagagaagca aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat gttttcaaca
    15361 acctatcgaa atcatcataa acgcttcgga ttacgaatga atttgattgc tggtattatc
    15421 aatcatgaac tagaattcta gttttgcagg aagtctatta tatacatgca cagacatatg
    15481 aaatcttttt gatacagcct tctttttaca tagagagaca gcaattatga tatatttatc
    15541 catgcacaac atcttctgag cctgggacaa aatagttctc gaccacaaaa aagctagaga
    15601 tttccaattg tggaactcta gctttttaat tttgagccgt tctcttattg tattttagga
    15661 gattattgac cataagtacc aatcccatgt caattctcac ttgacgcttc cctctcagat
    15721 tacatctctt gtaacccaaa gaagccttta tctgcccaaa gacaggttcc acatcaatct
    15781 tgcgttgagc gaaaatctgt ctaccttggg gagataaaag cgcctgacat tctttaactt
    15841 tcaagttttg atagcctttg ttcatataca gtcccttttg aggggctgat tcaggttcgt
    15901 cggtgtagta aatcttgatt tcttgttgaa agtctgtctg tgttttctga tgtttggtat
    15961 ggtgaaaacg ataataccag ccatcaggat gtgtgtagct atcctccttg ttatcatagt
    16021 gccaatttgc taagtttcta gctgactgtt tatagcctct cttctgttcc ttatcaaaca
    16081 tggcatattt aatcagatgg tttacctcct tttcatctaa acgaaggagg ttctcttcac
    16141 ttccctatcc agcatctgcg gcaactgtct tcaagtcatg cggataggtt tcaaggaatg
    16201 gcagaagagt cttggtgtct gtcggatttg aaaagacatc atagtgaaga acaaattggt
    16261 tttccgtagc gatttgaaga ttataagcag ccttgagttg accatttttc atatggtctt
    16321 ctttcatccg cataaaagtg gcatctggat cggttttgga aaaactgtta cgcccttcaa
    16381 atgtctcctg atagttctca tatttttcag cacgtattga aaaatcctcc ttgactttac
    16441 gcaagacttt cttgagtttc cgacgttggg ttttacgctc atccttccct ttaacgggtg
    16501 tctcctcaat gttctggttc aggttttcca attcttcttc aagaacttga gcgaatgcaa
    16561 gcaacggcaa atccgttgct ttttttggag ataagagact attgtcccag actcatttta
    16621 attacacaat cgtttcaaaa aatatgatgg aagcctgagt attttatagt aattcccttc
    16681 ctatcaacta ggtcaaccag ttgagtgtca caccctatcc tcagcaaagg actattgcca
    16741 ccatttccta gccgatagga ggctccaaac cacctattct aatactcaag agcaaactag
    16801 gaagccagtc gcaggctgct caaaatacta ttttgaggtt gcagatggaa gctgaccttg
    16861 tttgaagaga ttttcgaaaa gtataaaaac cacctgaaac aaatcaagtg actaaaggat
    16921 aaaaaacaaa gtctgggcaa aaagttttga aaatcaaaaa acgcataata tcaggtgttg
    16981 aaaaccttga tactatacgt ttgattgtgg gaagattgac ttcattttct cctgaaattg
    17041 agttttgctc agtttccaga gatagacgaa ttcaatataa ctatcttgct acaattattt
    17101 taaccatcga gaaaattttt cagaatttga aaaatttcat tttgatccaa tgaaatgtca
    17161 tcattttgag gaatagttga cttcacaggc tctaattcta tcacaaaacg gtgtatgtct
    17221 gcttttaccg cactacttga tgttatagcc gataactttt catctcctag caaggaagct
    17281 gtcaaacggg taatgtcatt caaatgcttt ttaatgaact tacttaaacc ttgagcacct
    17341 gtagcagagc gttccctcat atccagccaa gctttagcct taaaaataat taatactcaa
    17401 tgaaaatcaa agagcaaact aggaagctag ccgcaggctg tacttgagta cggcaaggtg
    17461 aagctgacgt ggtttgaatt tgattttcga agagtataga ccacaattac tcaataccga
    17521 atacccctga atgatctctt tttcatgcac caatatatta taataatcct catccaataa
    17581 taaggctgat aaactagcat cttggtcaaa atgtaaggga atttctcgac catccttctt
    17641 taatggatat tgtggtaaga tactaaatgg ttcaatcata gaaggaaact caggtttagt
    17701 tgttgtaaat cgaaaaagct gcgctttctc atctttctga cttccttgat actctcccaa
    17761 ttctaaaaaa tgattcaagg tattataaaa ttccttattt tttagttcat caatgatgac
    17821 catatcataa tcttttgttg tgcgactttt aaatccttgc gaatccaata cgatagaggt
    17881 agcagttccc ccaatcagaa cataatagtc cttaaaatcc gcaaacattt cttgaaaaat
    17941 agctttcata ttagctggca tcatcgtctc ccagatactg taatatcata ttttctagta
    18001 cttcactctc ttcctctata cgtgggtcat catcatcttt taaggtcaaa taaagagaaa
    18061 tcggatctac aaattgttta tcatgattat ttttaaaatc attccaaaac tcagatataa
    18121 aaggacaata tttccatatc tctaacacct ttccttctaa agcatgctga gaaagtggca
    18181 aggataactg attgaatttt ctctgccata tgacatagct agtattttca tccgtttcag
    18241 ctaaaaaagt tgaatgcgac aaagcataag taccaccata tagaaggtta gaaacagatt
    18301 ttatctgctt tatatcgcca tctggcaata aaatccgttt tttgatggga ttaaataaac
    18361 atgacacgga ttttaagaat aattctttct ttgacaccgt atatgtgtaa agcttatttt
    18421 gcttgtttaa ccaatctaaa gctttaaaag tcctcaaaca cctataaatt gttgagtttg
    18481 gaagtccagt cacccgtgaa agcaactcaa catctactac tttttgatct tttgtcaata
    18541 aaaaggcaat ccatgttaat tgttcgctag gtgttaattc cttagggact tcagtatcat
    18601 ccgcattcag tactagtccc aatgtaggga agaagaggtt tcccttgaag tcgacaaaag
    18661 ggattctagc ttgaagtaat tgcttttttt cgctgtctga taactttgaa aacaccaaaa
    18721 caacattcat attggctttt tcacccatag tacgagcctg agtaacaaat gaacttaaac
    18781 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
    18841 actcaaacct ttttacaaaa ctgattggta aagtcaaagc cagttcctca atactgacat
    18901 caacataaaa ggattgaaaa atcgacatta tctttttgac attcatggtt tttccttatt
    18961 ctatcatttt tattacattt tatcatttag tatgataaaa tacaaggttt ttgataaaat
    19021 aaccaaaaac tactcgctat cccctcttac atcaccctac atatcgttta acatacgact
    19081 gatagttcag gggaaacttc aaggacagct tttttctcat ccactatgca ggacttacta
    19141 tttcacttct actcctatag gctcaatttg acacttttct ttttcgaatt gctcatatgc
    19201 ctcctgaata gtgagttcga tttatccaaa tttatttttg tctattttga tgaatacttc
    19261 cacgaagata gtctgaaaat gaatttgcac caattttcct tctcttttta agcatattat
    19321 tccagatatg attgccctct tgttcagtaa taaattacgc tttaaacgct tcaaccagta
    19381 tatctcctgt tgtcatatgt tctaaagaaa attcttctac atatggttta acatctctta
    19441 ggttattact tcctaatatc ccattatgct ttttcgctaa ggaaatagaa gcagcttctc
    19501 ccttaccaat aatcttgtta ctatcatgat ttcttgttaa atctctatat aatgcgtatt
    19561 cttcagttcc aatgtctatg ctcacaatct cagctgaacc cttagttacc aactggtcta
    19621 tcctagattt taaatgggga attgtaggta tattgatttc atcatacacc tcttgtggaa
    19681 taacaatttt acccgaatag agcttttcta aaagttgttc agtcagattg atatattatc
    19741 ctaataccgt ttccttttta ctttctgaca aaggacgata taaacttgta tcatagccta
    19801 atcttgaagc tgtctctata acactaatat ccatattttt aatttcttct gcatcaaggt
    19861 atccatcatt cctcaatcta tataacatag ctttatgact gataccataa aactgaccca
    19921 attttataat atcttctact tcaagatgag ttctattggc attttctctg atttcctcaa
    19981 ccatcctata cagtgaagat gggaaaatta aaaaataaga agcaaactga tccgcttttc
    20041 tttcagtttc atctccttca ccaatcaaga taagactgac tgaactcttc ttcacctcat
    20101 cataataaag atgatacagt tcatgtgcta aagaaaatct ttaccttcct aataaatgtc
    20161 tgaattgatt gcaatgagac tgaactgagt tcctttataa cagactccgc taatattctt
    20221 tccgagtcca taaaatacca gcgtcaaatt ttatatcttt tgtaccaatt taaaaatatc
    20281 tatcggcgat tcaccatcag ctcccaactt ttttctaaga tttgaagctt tattacttaa
    20341 atccattcgt gatattcctt tcaccttttt ccattttggc aatcatgctt tgattcaaag
    20401 acaaatactc agcaatctta tcttgagtaa gatttgaaga tattctaagt tcttttattc
    20461 ttttccaaca tcacatacat ttatcacata catttatcat attcatacac ctctcataaa
    20521 aagaatagca cactcttgtc ataatttttt aaataaaaaa attatgacaa aataaggaag
    20581 caatttattg atgctgctta aaaatctaaa attgatgata ttaaacctat ttgatgagtt
    20641 cctatcaaaa atcgtatctt caacctcaaa acagtactta aagctatccg actcggttta
    20701 cattgtcaaa tttagatttt atttgagcat aactttctag tttgctttct gatttttgtt
    20761 taatatagta gcaaacattg aaggaaatat ctccacaaga aaacgcatac tattaagctt
    20821 tttcaagacc taataatatg cgctgttctg atttgaaaga cattccatta ttattttact
    20881 gtaatcaagc catctggctc tactgtgaat tctggcttgt ctgccagtgt tccgtctggt
    20941 ttgaggtagt accaacctgt tccgtccgct gactggataa aggcatttga taccatggcg
    21001 ccttctttag cgtctaagta gtaccaagtg tccttgtact tgacccagcc tgtcttcatg
    21061 gcaccttctt cgttgaaata gtaccacttc tcagcgattt tcttccagcc tgtggccatt
    21121 tcgcctgagt tgtcgaacca gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca
    21181 agcatatagc ctgaactgtc aaagtagtac caagtgtcgt tgaccttctc aaacttgtct
    21241 tttggataag agccgtctga atgtacgtac cagtagccag tgtcattctt ctgccagcct
    21301 gtttcaatcg tcaagccgtt ctcaatatca tgcttaaact gctcacggct aatgccccat
    21361 ttagcaagat atggataagg gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg
    21421 caatactcgt gcgttttaat tccagctaaa ctccctgtat caagcgtttt cggcaaacct
    21481 gcttcatctg ctagattgcg taagagttcg atataaaggc ggtagtctgt catgaactct
    21541 tctttagttg aatggctttc aatcagttca accgctgcat aggtctcagc attccaaccg
    21601 cccccaacgt cccaggcacc attatcaaca ggtcctacct gcatgatgca accgttccca
    21661 acaatgtgcg agaaaaaacc taattctggg tctttccgcc agtgataatc cgcttcattc
    21721 tgtacggttg aatgcggatt cccagttgag tgtgcgtgta cttgcctata tggttgcacg
    21781 ccgacttgag gcaaatctgt tcttaattta ctcacattaa tttccatatt ctactcctta
    21841 tcaattaaaa caactcattt tttacaatcc agaaccagaa actcctttat ttctacctta
    21901 caaagaagac aatcttagtc acgattaggc ttgtagatag aacctcaaaa cgcactattt
    21961 tgacactgta aataggactg acaaggtctg cattctatct acaataacac cccagactaa
    22021 aaagcttttc aaaagtatat ttttacagtc tctatatgtc cttttcataa atgctatact
    22081 ttattatatc atataaaaga agtcaaaagt ctgttaaact attttcaaca ccaaactaaa
    22141 gaggagaaca caagtttttt cgattctcac tagaggaaat ggattttatt cagtaaatcc
    22201 aactaggatt gcactttggt tgccaagatt gccttgcctt cttttatcaa gggatgacag
    22261 aatagtgaga agtacagttg aactgtcatg gcaacccaga taagaggttc acaaaggata
    22321 acacccttat atcctgccca atgaataatc aaaaccacaa aaacgatttt tccgattagt
    22381 tcaataaagc tagaaactag aggaaggatc ttttgcccca agccctgcaa gcaattgcga
    22441 taaatcaaca agaggctcaa aatgggataa aaggctgaac tgatttgcag atagagactt
    22501 ccattttcta tcaagtaacc atctgtcgaa ctagccaaga aggaaaccaa ggctggactg
    22561 gcaaaaaaga ggaaaataca aacaaaaact gcccaggata tacttaaacg actaccgatt
    22621 cgaagacctt gagcaatgcg gtcaggtcgc ttagctcctc gattctgaga agcaaaggta
    22681 gtcattgatg cagaaatagc ggtcatagga agaagggcaa agaccataat gcgtcgagct
    22741 gccgtctggg cactaataat cactgcacca aaggtattaa cagaagactg taaaattaca
    22801 ctgccgatag atacaattga actcatcaag cccatagcca aaccttgctc caagagatcc
    22861 gcgtacaagc tttcgtccca tttgaaatgt ttaaactgtg gcaagagttc tggcacactt
    22921 ttacgaatat aataaaagca gagaaccgct gataaacctt gcgaaataat ggtagcaagt
    22981 cctgcagatt gaactcccag atgcaattgc gtaataaaat agagatctag aaccacatta
    23041 accaagtcag agaaaatcag aaatcccagg gctgctagac tgtcaccaat agaccgcaac
    23101 aagcctgtaa aaagattata agcaaagctg acacctacac aggtcacaat catagaaata
    23161 tattgataag attgaggaag aatttctgca ggagtatcta agtattgcaa gagaggatac
    23221 aagccaagaa agcccagcaa cataactaga atgctcaaaa gagcacctaa aatctaagtg
    23281 gctgctactg cttccttgat tttagtgaaa ttccgagccc cataataacg agcaatgaca
    23341 atccccatgc cattgccaac accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc
    23401 gtcgctccta ctgcagccaa ggattcttga ccaagaaatc gtccaacaat caagacatca
    23461 gcagtgttat agagctgttg aaaaatattt gatagcaaga ttgggaaggt gaagcttaag
    23521 aacgagggaa gaatcgaacc atgtatcagg tccactgttc gttgtttatt cataaagcta
    23581 ttatatcaac tttctagagg agcgacaaga aacagcaaac tatatatagc aaaatgaaat
    23641 aaaaacagga taaatcaatc aggacagtca aatcgatttt taacaatgtt ttagaagtag
    23701 atgtgtacta ttctagtttc gatctattat agttggttga gtttggaata gtaagctgta
    23761 gctgctaaaa tatttctaga aattaatttg actttcctaa tagagttgtt catatcttat
    23821 ttcaatctac tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc
    23881 tccactactt taacagctta ttcttcaatt tcaatttcaa gttcatcgcc taggtcaagc
    23941 gtaacttctt cattcactgc ttcttctttc tttggctcat cttttttgtt ttcaatatct
    24001 tgttctgaag cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt
    24061 tcatcaaaga tttctgggtg ctccgccaag tatttcttag cattctcaga accttgccca
    24121 attttttcat ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt
    24181 gcaatcttca aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg
    24241 gcttccttaa acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg
    24301 acattggttt ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag
    24361 cggactgaag catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac
    24421 atcactccaa ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg
    24481 atagaggcgc caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg
    24541 ctatctccga tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact
    24601 acgacaagat caactgcacc tgagtcaatc aattttcccg caatttcaag accttgctct
    24661 cctgagtctg gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa
    24721 gctggatcaa gggcatgttc cgcatcgata aaggcagcaa tcccaccttc tttttgcgct
    24781 tgtgcaactg catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg
    24841 atgatacgtc ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct
    24901 gagctcatca cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta
    24961 ccaaagtctt tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca
    25021 aatttttttg aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt
    25081 ctaatgttcc tcagacctat ctactattat atcaaaagtt agtcacttaa taaagccttg
    25141 cgaactaggt taaaggcatg cataaccgca atatgacgta catctgctcg gcttctgcct
    25201 ccaatattaa cattgataac ctcagtttct tgctcttgcg ccaagcctat gaagactgtc
    25261 ccaactgggt gtccttctag gctatctggt cctgccactc cagtcaaact aactccaaaa
    25321 tcagactggg tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc
    25381 acaccatgtt cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag
    25441 ctataggtca caaaaccacc cttaaatata cttgaagctc cagaaaaatt cgccacggta
    25501 gcttggaaaa gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc
    25561 agttcttcta ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct
    25621 cgtaaagaaa ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc
    25681 gcttgattcg cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct
    25741 gtcttggcat aaggggccaa ggtaggatcg atctgattat caattaaatc agccaaaatc
    25801 gtaaccagct ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc
    25861 cctgtcatca acttgggtag aagttggttt aagaccatgg gtttcaattc acttggcgga
    25921 cctggaagga cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct
    25981 gtttcgtttg gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt
    26041 gttcgggcat agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga
    26101 tcaaagacta atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca
    26161 gttggcccca aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc
    26221 aaagacaaga gacgaacttc attgtctcct acagctgtct gaaaatatac atctacccca
    26281 atctcagcta gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa
    26341 atctctgttc caacagcaat gatttctgct ttcatatttc ctcctaccta tctattcgta
    26401 tttttttgaa aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt
    26461 aattatcttc atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accacattgg
    26521 tttcaagctg agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca
    26581 acatatgtac tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct
    26641 gcaactgctg agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac
    26701 tttttgcaga caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt
    26761 gataatgacc aacgctattt aaactgagag ctttttccat gactttttga ataacttcac
    26821 gttgacgttt ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga
    26881 ctagggcttc ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt
    26941 cttcttggtc actgatagaa attgggaaac ctaggatatt attgactgta atacctccta
    27001 ctgcatccac tagtttttgc aaccctctca tattgaccat tacatagcga tcaatatgga
    27061 tattcatcat tttttgaatg gtttctatag caagctctac tccaccatct gcatatgctg
    27121 agttcagttt cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatgtccc
    27181 gctctaaact catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc
    27241 tatcacttct accgacccaa gtttcagttc gttcagcatt tccggtgtcc actcccatta
    27301 acagaatggt tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat
    27361 aggttttagc taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc
    27421 ctactacagt tacagaaagt aaagctagca ccattccaat aattttttta accatatttc
    27481 tactaaccta tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat
    27541 gccccacgct cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct
    27601 gcttgattac gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc
    27661 cactctatcg cttcttctag caacaaactt cccaagccat tattccaata tctttttcca
    27721 atcacaatga agagatctcc aatatgacgg actctcttac gctggtcagc tgtaatattt
    27781 acaataccag caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta
    27841 gcttgcttgt tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct
    27901 aggctggtaa agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca
    27961 tctttgggct ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa
    28021 tttctcagca cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag
    28081 aatttccaat tctaaataag tatctggcaa ggcatctcct aagagatttc cccactcaat
    28141 aacagtcacg ccaccaccaa agataaactc atccaagtcg atagaatcag catctccttc
    28201 aatacgataa acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt
    28261 ataggtggga cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa
    28321 ggtcgtttta cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag
    28381 atggcccaaa cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt
    28441 attataccaa aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc
    28501 cataaaaaac aggctttctc taaaagaaaa tgagcgtagc aatgaccaat acaagatctc
    28561 ggaaaatatg accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg
    28621 caaaaaacaa gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta
    28681 agaaaagaag tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa
    28741 gaaaatcgcg cacgtatttt ttcaagggta aaaaaatcag caaatctagt ccaaatagga
    28801 aaaagaagga tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca
    28861 agttatctga caaaacaaga acagctccta acaaattaat taagagtaac atactataaa
    28921 aaagcttcac cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa
    28981 gataatttac tccagcacag attcctgaaa cgaaaaccat gcttccgatg aaaaaagctg
    29041 tactttgttt aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt
    29101 gaattaaagc taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc
    29161 aatcattata ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag
    29221 acgctaaaca aacactagag actaatactc aataaaaatc aaagagcaaa ctaggtagct
    29281 agccacaggt tgctcaaaac actgttttga gattgcagat agagctgacg tggtttgaag
    29341 agatttttga agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggtttatcct
    29401 agagctataa gcccaaatca tcagccagcg tctttaggcg ctggctttca cgttgttcaa
    29461 gccttattgc tcttgactcg tcacttgcct ctttaagagg ctttagtatt acttaccact
    29521 atccctaaag ggagcctcat attcttttac actcaattta tctagtgcta tagtagattc
    29581 aaactggaat agtacacctc tacttctaaa acattgttaa aaatcgattt gactgtcctg
    29641 atcaattttg tcctgttctt atttcatttt actatatatc atgctttact cgttctcaaa
    29701 ttttcatact cgtgaagaaa tcatccactc gataatttct ttaatcttga ctatacttct
    29761 taattgtggc tttgttaagc cctactgtgc tcacataata accttccgcc cagaaatgcc
    29821 gattcccaaa cttgtacttg agattggcat gtttgtcaaa catcatgagt gcacttttgc
    29881 cttttaaaca ccccataaaa cttgaaacac ttagcctcgg cggaatactg actaacatat
    29941 gtatagtgta ttgaagctat aacagtacat cttgactgct aaaatatttc tataaattaa
    30001 tttgactttc ctgatagagg atgttcacat cttatttcaa ttcactatac atgttcaggc
    30061 attaagtgac cctcgataat ttcaacacct ttataactac acaagcgatg aaatatttct
    30121 cccaaactac ttcgatattg attataaatg actgttcgtc tatacctagg ggtgaacaca
    30181 atgtgataga acacatccac tttgtgtatg ataaactatg tgctttttgt gccatatttt
    30241 tctcctttcg ctttataatt ggcttgaaca cctttattgt atcgcgtttg gagttttttt
    30301 ggtataacct tcgacgcgca cccgcatagc gggtggttgt tttgtctcgc acctaacgga
    30361 gcgagacgaa ctaatagtca cttaatcaaa aaacgcacca tatcaaaacc taaaaagttt
    30421 gatatcatgc gtcatgtctt aaactaattg actatacttt ctattcaaat gagcttttaa
    30481 ccaattgatt gagccaatcc actcttaaaa ccaaagagca atttctcgct tagctgactc
    30541 ttctgaatct gaaccatgta caacattttg gataacctca ttttcttcag cagcttttgc
    30601 aaaatcacct cgaatagtgc ctggtaaagc ttcttctgga cgagttgcac ccatcatggt
    30661 ccgccaaatt tcgattactt tggtaccaga aatgacaccc acaagaactg gacctgaagt
    30721 catgaattca cgaatcggtg ggtaaaaact ctgaccaacc aagtcctgat agtgctggtc
    30781 aatcaactct tctgaaacct gtgaacgaaa ctccaatttt tcgattgtaa atccacgttg
    30841 ttcgatgcgc tttaacactt cacccactag tcctcttttt acaccatctg gtttgatgat
    30901 aaagaatgtt tgttccatac tcgtctcctt tgtcagcttc tttcttttat tttaccacat
    30961 ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaacccga gggttctctt
    31021 attctactgt ttcttccaca gtttcaacgg cagtatccac aactacttct gttgtttctt
    31081 catttccttc ttcctctact ggaggattaa ggtattcttc ttcgttgaca gcatgtggtt
    31141 caaggttacg gtaacgggcc ataccagtac cagctgggat gatcttaccg atgataacat
    31201 tttctttaag tccaaggaga tggtctttct taccacggat agctgcgtca gtaaggacac
    31261 gagttgtttc ctggaaggaa gccgctgaca agaaactgtt tgtttcaagt gaggctttgg
    31321 taattcccat aaggactggg cgacctgtcg ctggaactcc acctgcgata aggacatctt
    31381 tgttggcatc tgtaaagtca ttgatatcca tgagggtacc catgagaaga tctgtatcac
    31441 ctggatccat gacacggact ttacggatca tttgacgaac cattacctcg atgtgtttgt
    31501 caccgatttc taccccttgg ctacggtaaa ctttttgtac ttcaccgaga aggtacgttt
    31561 caactgacaa gacatcacga actgcaagga gacgttttgg ttggatagaa ccttctgtca
    31621 gagcagcacc acgcgctact tggcccccaa cttcgacacg catacgagct gtaaatggaa
    31681 cgacatattc accttcgcca gtttcaccct taacaaagac tttcttggta cgagttgatg
    31741 catcttcttc gatagcagta acttgtcctt taacctctgt gataaccgct tcccctttag
    31801 gattgcgggc ttcaaagatt tcttggacac gaggaagacc ctgagtgata tcggtatttg
    31861 aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg tgtaccaggt tccccgatag
    31921 attgggcagc gattgtacca actgcttcac caacttcaac cgcatcacca gtcgccaagt
    31981 tgataccgta acagtgacgg cagacaccgt gacgagtgtt acatgtaaat acagaacgga
    32041 tagtcacttc ttccacacca gcattgacaa tttcacgcgc cttgtcttct gtaatcaatt
    32101 catttggacc aataatcact gcaccagttt ctggatgttt aacagttttc ttagtgtaac
    32161 gaccgttgag acgctcttcg agagactcga tcatctcttt tccttctgcg atagaacgga
    32221 tcaagagacc acggtcagtt ccacagtcgt cctcacggat gataacgtct tgggcaacgt
    32281 cgaccaaacg acgagtcaag taacctgagt cggctgtctt aagggccgta tcggtcatac
    32341 ctttacgagc accgtgagtt gagaagaaca tttccaatac cgacaaacct tcgcggaagt
    32401 ttgaaaggat tggcaattcc atgatacgtc cattcggagc agccatcaga ccacgcatac
    32461 cggcaagctg tgagaagttt gagatgttac cacgggctcc agagtccatc atcataacga
    32521 ttgggttctt aggatcttgg tcagcaatca agcgtttctc aagtttttca cgggcagcac
    32581 gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt gatcatacca cgacggaatt
    32641 gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat gatttcagcc ttgtcatcaa
    32701 cgactgggat atcggcaata cccactgtca atcctgcaag agttgagtgc tggtaaccga
    32761 ggttcttcat gcggtcaagt agggcagaag tttctgtcgt acggaaacgt ttgaagattt
    32821 cagcgatgat atttccaagg tttttcttct tgaatggagg gttgagttca agattgctga
    32881 tagcttcctt gatatctcca ccaagtggca agaagtattt agctggaaca ccttctgtca
    32941 agttgccatt gtttggttct tgcaagtatg gtagcccctc tggcatgata tcgttgaaga
    33001 gaactttacc aactgttgta agcaagacct tatgtctttg ctcttctgtc caaggcttgt
    33061 tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg aacataacca ttgcggtaag
    33121 ccataaccgc ttcgtcacga tctttgaaga ccattccttc gccttcccga ccagcttctt
    33181 ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga tggagtaact accggtttcc
    33241 catctttcgg gttcaagatg tgctcagcag ctagcatgag gatacgagct tctgcttgtg
    33301 cttcttctga aagtggtacg tggatggcca tttggtcccc gtcaaagtcg gcattgtagg
    33361 cttcacagac aagtgggtgc aagcgaagag ccttaccatc aatcaagact ggctcgaagg
    33421 cttggatacc caaacggtga agggtcggtg cgcggttcaa aagcactggg tgttctttaa
    33481 tcacttcttc aaggatatcc cagatacgct catctccgcg ttccaccaag cgtttagctg
    33541 ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg catgacaaat ggtttaaaga
    33601 gttcaatcgc catttcacgc ggcacaccac attggtacat cttaagagtt ggaccaacgg
    33661 cgataacgga acgtcctgag aagtcaacac gtttaccgag caagttttga cggaagcgtc
    33721 cttgtttacc tttaagcatg tggctcaatg atttcaatgg acggctacct ggccctgtga
    33781 ttggacgacc acggcgacca ttgtcaatca aagcgtcaac cgcttcttga agcatacgct
    33841 tctcattttg aacgatgata cctggtgcat ttaactcaag caaacgagcc aaacggttgt
    33901 tacggttgat aacacggcgg taaaggtcat tcaagtcaga tgaggcaaaa cggccaccat
    33961 ccaactgcaa cattggacga agatctggtg ggataaccgg aaggatgtta aggatcatcc
    34021 attcaggttt gtttccagac ttgtaaaagg catccaaaac atccaaacga cggatggctt
    34081 taacacgttt ttgtccggta gctgttttca attcttcttt gagttcagca atttcttttt
    34141 caagatctac ttgcttcaaa aggtcttgga tggcttcggc acccatcttg gcaacaaatg
    34201 aaccataacc atattcgcgc aagcgctctc ggtattcgcg ctctgtcatg atagacttgt
    34261 gctcaagtgg tgtatcctta ggatcaatca ccacataagc cgcaaagtag ataacttcct
    34321 cgagggcacg agggctcata tcaagggtca agcccatacg gcttggaatc cccttgaagt
    34381 accagatgtg agatacagga gctttcaatt cgatatgtcc catacgctca cgacgaactt
    34441 tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat tcctctgtaa cgaatgcgtt
    34501 tgtacttacc acaagcacat tcccagtctt ttgtaggacc aaagatcact tcatcaaaga
    34561 gtccttcacg ttctggtttc aaggtacgat aattgattgt ttcaggtttt ttgacttctc
    34621 cataagacca tgaacggact ttacttggag aagctagggt gatttgcata cttttaaaac
    34681 gatttacatc aaccactatt tcttcccttt ctattcgtaa gtgaactgct tattcttgtt
    34741 cagcagcttc ttctgttgct tccgcttttg ttgctttctc agcgtcttca gcttcaaagg
    34801 ctgctttagc ctcttgggct gctttttcac gggctttttc aaggtcatct acgtggatga
    34861 catcttcgtc cattccttca tccaagtcgc gaagttccac ttcttggtca tcttcgtcta
    34921 ggacacgcat gtcaagacca agagattgca attctttgac aagaactcgg aaggattctg
    34981 gaacacctgg ttttggaatt ggtttgcctt ttgtaatagc ttcataggct ttcaaacgtc
    35041 cgttgatatc gtcagacttg taagtcaaga tttcttgaag gacatttgac gcaccgtagg
    35101 cttcaagagc ccaaacctcc atctcaccga aacgttgtcc accaaactga gctttacctc
    35161 cgagtggttg ttgggtaaca gttgagtaag gtccgactga acgcgcgtgc aatttatcgt
    35221 caaccatgtg gtgaagtttg atcatgtaca tgactccaac agaaacacgg ttatcaaatg
    35281 gttcacctgt acgtccatcg taaaggattg tcttggcatc gctatccata cctgcttctt
    35341 taacagttga ccaaagatct tcagaacttg ctccatcaaa gactggtgtc gcgatgtgaa
    35401 taccaagagt acgagctgcc ataccaaggt gaagctccat aacctgaccg atattcatac
    35461 gtgatggcac cccaagtgga ttcaacatga tgtcgactgg agttccgtct ggaaggtaag
    35521 gcatgtcttc tacaggaacg atacgagaga caaccccttt gtttccgtga cgtccggcca
    35581 ttttatctcc gaccttaatc ttacgttttt gagcgatgta aacacgaacc aacatgttaa
    35641 cacctgattg caactcatct ccatttacac gtgtaaagat cttaacatca cgaacgacac
    35701 catcggcacc gtgtggtaca cgaagagaag tatcacgcac ttcacgagac ttgtctccaa
    35761 agatagcgtg caagagacgt tcttcagctg aaaggtcttt ctcaccctta ggtgttactt
    35821 tacctacaag aatatcacct tctttaacct cagcaccaat acggataatc cccatttcgt
    35881 caaggtcttt gagggcatct tcaccaacgt ttggaatttc gcgagtgatt tcttcaggcc
    35941 caagctttgt atcgcgcgtt tctgattcgt attcttcaag gtgaacagat gtgtagatat
    36001 cgtccttcac caagcgttcg ctcatgacaa cggcatcctc gaagttgtaa ccttcccaag
    36061 tcatgtaggc aacgattggg ttttgtccaa gcgccatttc tccattttcc atagaaggtc
    36121 cgtcagcgat gaaatcgcct ttttcaacga catcaccaac ttttacgaga gtgcgttggt
    36181 tgtaagcagt acctgagttt gaacgacgga atttttggat gtggtaaaca tccaatgaac
    36241 catcttcacg acgaacttct accttgtcag catctgcgta agtaacttta ccatcatact
    36301 gagcaatcac agccgcacca gaatcgtggg ctgcttggta ttccatacca gtaccaacgt
    36361 aaggtgcctg aggattaatc aatggcacag cctgacgttg catattggct cccatgaggg
    36421 cacggttgga gtcatcgttt tccaagaaag gaatacatgc tgtcgcaacg gcaactacct
    36481 gttttggtga aacgtccatg tagtcaacaa tattagctgg atactcttgg ttgacccctt
    36541 ggtgacgtcc catgacaatc ttctcagcaa aggttccatc ttcattcaga cgagagttag
    36601 cctgagctac agtatattca tcttcttcat cagctgtcaa ccaaacaatt tcgttcgtga
    36661 caacacctgt ttcacggtca accttacggt atggtgtttg aacaaaacca tatttgttca
    36721 agtgtccgta agatgacaag ttattgatca aaccgatgtt aggtccttca ggtgtctcga
    36781 ttggacacat acgaccatag tgagtgtagt gcacgtcacg tacttcatat ccggcacggt
    36841 cacgagtcaa accaccaggt cctaaggctg acaaacggcg tttgtgagac aactcagaaa
    36901 gcgggttgtg ttggtccatg aactgtgaca actgtgatga accaaagaat tctttaactg
    36961 cagctgttac aggacggata ttgataattt gttgtggtgt caagacttca ttgtcctgaa
    37021 cagacatacg ttcacggaca ttacgttcca tacgagaaag tcccaaacgt acttggttgg
    37081 caagcaattc accaaccgca cggatacgac gatttccaag gtggtcgata tcatctacac
    37141 ggccaagtcc ttcagccaag ttgaggaagt agctcatctc agcaaggata tctgcaggag
    37201 tcaccgtacg aaccttgtca tctgggttag cattaccaat gatcgttacg acgcgatctg
    37261 gatcagttgg agcaacaacc ttgaattttt gaagaacaac aggctcagtc acaacggctg
    37321 catcgtttgg gatgtagaca atcttgttca agtcgccatc caaatggctt tcaatacttt
    37381 caatcacgct acgagtcata atcgtaccag cttctaccaa gatttctcca gtttcagggt
    37441 ctaccaatgg ctctgcaatg gtttggttga gcaaacgtgt tttaacattg agttttttat
    37501 tgattttgta acgaccaact gctgccaagt catagcgacg tgggtcaaag aagcgagcca
    37561 caagcaagct acgtgagctt tcagctgtct taggctcacc tggacgaagg cgttcgtaaa
    37621 tttctttcaa ggcttcgtct gtacgagagt ccattggatt cttgtggata tctttttcaa
    37681 cagtgttgcg aaccaattcg ctgtcaccaa agatatcaaa gatttcatca tcacctgaga
    37741 aaccaagagc acgaaccaag gttgtaaatg gaatcttacg agtacggtcg atacgagtgt
    37801 aggtgatatc ttttgagtcg ctttcaagtt ccaaccaagc tccacggtta gggataacag
    37861 ttgaaccata gcccacctta ccatttttgt ctactttgtc gttaaagtaa acacctggtg
    37921 agcggaccaa ctgagaaacg ataatacgtt caccaccatt gatgatgaaa gtacccattt
    37981 ctgtcatgat tgggaaatca ccaaagaaaa cttcttgggt cttgatttcg cctgtttctt
    38041 tattgatcaa gcggaaggtt acaaaaattg gtgctgagta gctagcatcg tggatacgag
    38101 cttcttctag cgtgtatttt ggttccttga tttcatatcc aacaaattcc aactccattg
    38161 tgtctgtgaa gtttgaaatt ggcaatacat cttcaaacac ttccttaaga gcgtggtcta
    38221 ggaaagcttt gaatgagtca gtttgaattt caatcaaatt tggtaagtca agaacttctt
    38281 tgattcttga aaaactacga cgggtacgat gtttcccgta ttgaacgtca tgtcctgcca
    38341 agatgattct cctttgtaaa taagttccaa gccttgtcaa tcaggctttt ctaatcgcca
    38401 tatggttgta aaccccttat caccgtgtcc tcttgacgaa ttttcagaat ctttaagcct
    38461 ctgttacaaa tgctcaaaat cttgaaaaaa agcacaaaaa gagcagctaa atctgacttt
    38521 ttcagaagat ttaactgctg tgagccttgt ctggacaata tttcagacaa aacctacgac
    38581 aaatgattac ccatattata ccctatttag ctagattttt caagggaatt cagtaggttt
    38641 ttggtaattt ttttcccata gaaaacttgg catcacattc gaatcacgct atggtacaaa
    38701 aaactgaaaa aactattgac tgaaaatcat tttca
//
LOCUS       DAVDHZ010000016        38560 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000016 DAVDHZ010000000
VERSION     DAVDHZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.016"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            93..920
                     /gene="xth"
                     /locus_tag="VUR46_001002"
     CDS             93..920
                     /gene="xth"
                     /locus_tag="VUR46_001002"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET5456444.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            932..1075
                     /locus_tag="VUR46_001003"
     CDS             932..1075
                     /locus_tag="VUR46_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET5456445.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            1186..1314
                     /locus_tag="VUR46_001004"
     CDS             1186..1314
                     /locus_tag="VUR46_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HET5456446.1"
                     /translation="MKANYPIYRPLTKRKFRVSDHYIYPHEFAVLDPNGYFLRFSE"
     regulatory      1698..1793
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            2193..2774
                     /locus_tag="VUR46_001005"
     CDS             2193..2774
                     /locus_tag="VUR46_001005"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET5456447.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAEKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            2774..4036
                     /locus_tag="VUR46_001006"
     CDS             2774..4036
                     /locus_tag="VUR46_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET5456448.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(4123..4989)
                     /locus_tag="VUR46_001007"
     CDS             complement(4123..4989)
                     /locus_tag="VUR46_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HET5456449.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(4976..5746)
                     /locus_tag="VUR46_001008"
     CDS             complement(4976..5746)
                     /locus_tag="VUR46_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET5456450.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(5772..6626)
                     /locus_tag="VUR46_001009"
     CDS             complement(5772..6626)
                     /locus_tag="VUR46_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET5456451.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDVFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(6783..7187)
                     /locus_tag="VUR46_001010"
     CDS             complement(6783..7187)
                     /locus_tag="VUR46_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET5456452.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(7257..8738)
                     /locus_tag="VUR46_001011"
     CDS             complement(7257..8738)
                     /locus_tag="VUR46_001011"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET5456453.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            complement(8757..9935)
                     /locus_tag="VUR46_001012"
     CDS             complement(8757..9935)
                     /locus_tag="VUR46_001012"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET5456454.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPATISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDALVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            10099..11106
                     /gene="galR"
                     /locus_tag="VUR46_001013"
     CDS             10099..11106
                     /gene="galR"
                     /locus_tag="VUR46_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET5456455.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(11152..12144)
                     /locus_tag="VUR46_001014"
     CDS             complement(11152..12144)
                     /locus_tag="VUR46_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET5456456.1"
                     /translation="MDLRPQIIEADDVIIRVVRACVCGSDLWRYRNPETKAGHKNSGH
                     EAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGSCDNHIGNNLGGDFQA
                     EYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHAARVANVQKGDKVVVI
                     GDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVVAERGQEGITKVREIL
                     GGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRALGSTFMQNISVAGGAA
                     SATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDERKTIKSMIVIE"
     gene            complement(12179..12532)
                     /locus_tag="VUR46_001015"
     CDS             complement(12179..12532)
                     /locus_tag="VUR46_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET5456457.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(12776..13666)
                     /locus_tag="VUR46_001016"
     CDS             complement(12776..13666)
                     /locus_tag="VUR46_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET5456458.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGIFGSSAVLADSVHDLVDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINMLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            13799..14335
                     /locus_tag="VUR46_001017"
     CDS             13799..14335
                     /locus_tag="VUR46_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET5456459.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(14502..15308)
                     /locus_tag="VUR46_001018"
     CDS             complement(14502..15308)
                     /locus_tag="VUR46_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET5456460.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKTIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(15653..17173)
                     /locus_tag="VUR46_001019"
     CDS             complement(15653..17173)
                     /locus_tag="VUR46_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET5456461.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(17166..17894)
                     /locus_tag="VUR46_001020"
     CDS             complement(17166..17894)
                     /locus_tag="VUR46_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456462.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(17909..18673)
                     /locus_tag="VUR46_001021"
     CDS             complement(17909..18673)
                     /locus_tag="VUR46_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET5456463.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     CIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(18677..19120)
                     /locus_tag="VUR46_001022"
     CDS             complement(18677..19120)
                     /locus_tag="VUR46_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5456464.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(19802..20098)
                     /locus_tag="VUR46_001023"
     CDS             complement(19802..20098)
                     /locus_tag="VUR46_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET5456465.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(20120..21184)
                     /gene="pepA"
                     /locus_tag="VUR46_001024"
     CDS             complement(20120..21184)
                     /gene="pepA"
                     /locus_tag="VUR46_001024"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET5456466.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKLDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            21585..22286
                     /gene="galE"
                     /locus_tag="VUR46_001025"
     CDS             21585..22286
                     /gene="galE"
                     /locus_tag="VUR46_001025"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET5456467.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNASGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            22709..23668
                     /locus_tag="VUR46_001026"
     CDS             22709..23668
                     /locus_tag="VUR46_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456468.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWVLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            23658..24614
                     /locus_tag="VUR46_001027"
     CDS             23658..24614
                     /locus_tag="VUR46_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET5456469.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLNCLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            24611..25363
                     /locus_tag="VUR46_001028"
     CDS             24611..25363
                     /locus_tag="VUR46_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5456470.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            25459..26424
                     /locus_tag="VUR46_001029"
     CDS             25459..26424
                     /locus_tag="VUR46_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5456471.1"
                     /translation="MKTSLKLYFIALVASFLLLLGACSTNSSTSQTEPSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(26649..26891)
                     /gene="yidD"
                     /locus_tag="VUR46_001030"
     CDS             complement(26649..26891)
                     /gene="yidD"
                     /locus_tag="VUR46_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET5456472.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMSLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(26891..27613)
                     /locus_tag="VUR46_001031"
     CDS             complement(26891..27613)
                     /locus_tag="VUR46_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET5456473.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(27600..28169)
                     /locus_tag="VUR46_001032"
     CDS             complement(27600..28169)
                     /locus_tag="VUR46_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET5456474.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(28188..28916)
                     /locus_tag="VUR46_001033"
     CDS             complement(28188..28916)
                     /locus_tag="VUR46_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET5456475.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(28916..29656)
                     /gene="xerD"
                     /locus_tag="VUR46_001034"
     CDS             complement(28916..29656)
                     /gene="xerD"
                     /locus_tag="VUR46_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET5456476.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(29647..30108)
                     /locus_tag="VUR46_001035"
     CDS             complement(29647..30108)
                     /locus_tag="VUR46_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5456477.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(30105..30626)
                     /locus_tag="VUR46_001036"
     CDS             complement(30105..30626)
                     /locus_tag="VUR46_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET5456478.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(30602..31573)
                     /locus_tag="VUR46_001037"
     CDS             complement(30602..31573)
                     /locus_tag="VUR46_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET5456479.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(31570..32364)
                     /gene="racE"
                     /locus_tag="VUR46_001038"
     CDS             complement(31570..32364)
                     /gene="racE"
                     /locus_tag="VUR46_001038"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET5456480.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(32571..32819)
                     /locus_tag="VUR46_001039"
     CDS             complement(32571..32819)
                     /locus_tag="VUR46_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET5456481.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(33075..34700)
                     /gene="treC"
                     /locus_tag="VUR46_001040"
     CDS             complement(33075..34700)
                     /gene="treC"
                     /locus_tag="VUR46_001040"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET5456482.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(34878..36845)
                     /gene="treP"
                     /locus_tag="VUR46_001041"
     CDS             complement(34878..36845)
                     /gene="treP"
                     /locus_tag="VUR46_001041"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET5456483.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTINRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            37030..37740
                     /gene="treR"
                     /locus_tag="VUR46_001042"
     CDS             37030..37740
                     /gene="treR"
                     /locus_tag="VUR46_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET5456484.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVGRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            37895..>38560
                     /locus_tag="VUR46_001043"
     CDS             37895..>38560
                     /locus_tag="VUR46_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HET5456485.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKMSMTDIAHQLSISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQ"
BASE COUNT        11301 a         8888 c         7121 g        11250 t
ORIGIN      
        1 cgaaagagag taatttttca aactatacgt tggggaaata gatctttttt tggtataata
       61 aaatctataa tctgaatgaa aaaggtaact ttatgaaact tatctcatgg aatattgatt
      121 ccctaaacgc tgccctaact agtgactcag ctcgtgccaa attgtcccaa gaagtcctac
      181 aaaccttggt cgctgaaaat gctgatatca ttgctatcca agaaaccaag ctttctgcca
      241 aaggacctac aaagaaacac gtggaaattt tagaagaact cttcccaggc tacgaaaaca
      301 cgtggcgttc ttcccaagag cctgcccgta aaggctatgc tggaaccatg ttcctttata
      361 agaaagaact tacacctact atcagcttcc cagaaatcgg tgccccttct accatggact
      421 tggaaggtcg tatcatcact ctagaatttg atgcattttt cgtaacccaa gtttacactc
      481 caaacgctgg tgacggtctc aaacgcttgg aagaacgcca agtctgggat gccaaatatg
      541 ctgagtattt ggctgaacta gacaaagaaa aaccagtcct tgcgaccggt gactacaacg
      601 tagcccacaa tgaaatcgac cttgcaaatc ctgctagcaa ccgccgttca cctggattta
      661 ctgacgagga acgtgctgga tttaccaacc ttttggcaac tggatttaca gacaccttcc
      721 gccatgttca tggcgatgtt cctgaacgct acacttggtg ggcacaacgc agcaaaactt
      781 ctaaaatcaa caatacaggc tggagaatcg actactggct cacaagtaac cgtatcgctg
      841 acaaggtcac taaatctgat atgattgact caggtgctcg ccaagaccat acaccgattg
      901 tcttggaaat tgacttgtaa ggattttcta tatggactac aatgcggtca ttcccgagtt
      961 gcttgtatcg aatatcgaac agtcccggtc cttctactgt ggtttactgg gttttaggat
     1021 tgaataccaa cgtccagaag aaaactttct ctttctcttg aagagtgtca actaatgtta
     1081 gaggagggaa caaaggatca actagctgaa ctgacctatc catttggtcg tggagtcaat
     1141 ctctcctttg gcataaagga tgtttcaaaa ctctattaaa gagtgatgaa ggcaaactat
     1201 cctatttatc gtcccttgac caagagaaag tttcgtgtca gtgatcacta tatctatcct
     1261 catgaatttg cagttttgga tccaaatggc tattttttaa gatttagcga gtagaataat
     1321 aaaaattggg aaaagtcttt aaagttagaa aaaggcatat tgtcaggtgt ttaaaaactt
     1381 gatagtatgc cttttatgat ggaaaaatct tctaatactc ttcgaaaatc tcttcaagcc
     1441 acatcaacgt tgccttaccg taggtatatg atactgactc tgtcaattct atccacaacc
     1501 tcaaaacagt gatttgaggt tgtggatagc ttcctagttt gctctttgat tttcatttag
     1561 tataaatgtt agcttacaac ggagtttttt gttcgccctc tcttctgttt gttcgttttt
     1621 taaaccaaaa cactaacaaa atagttgatt tctaaagtta tttagtgtaa aataaaaaca
     1681 ttggctcaag cctatttaaa attgaatatc gttttacttg tttatgtcgt gaattggcac
     1741 gacgtttcta caaggtgccg gaacacctaa caataagtaa gtcagcagtg agatatggcc
     1801 gtttttgcca tgcctatttg ggggacttac ttagagatta agtaggtctt ttttgaatat
     1861 ttttaatatt tcccttaatt agtgcggacg ggaggtgaaa ttatcctgtg aataatttca
     1921 ggaatccagg gaatttcatc cctaattttt gagcccctag ctctttcatt tctaggctta
     1981 ggctaaaata gttccccgaa ctattttact ctcaaaaatc ccgtcataga caataacaag
     2041 attattgtct atgataccac tacatcagga aatatttgat aagactcgct tcgctcgtaa
     2101 tagttttatc aaatatatag tattagcaaa agggatcact atagaaatat ttaaacaaca
     2161 agtaaattaa cttttagact ttaggaggtc ttatgaaatt attagaagag cgcatcctca
     2221 aggatgggca tatcttgggt gataacatcc tcaaggtaga ttccttttta acccaccaag
     2281 ttgactttag cttgatgcga gagattggta aggtttttgc ggaaaaattt gctgctactg
     2341 gcattaccaa ggtcgtaacc attgaagcgt cgggtattgc cccagccgtt tttacagctg
     2401 aagccttaaa cgttcccatg attttcgcca aaaaagctaa gaacatcacc atgaacgaag
     2461 gcatcttaac tgctcaagtc tactccttta ccaaacaggt gaccagcacc gtttctatcg
     2521 ctgaaaaatt cctctcacca gaggacaagg ttttgattat cgacgatttc cttgctaatg
     2581 gccaagctgc taaaggcttg attcaaatca tcgaacaggc cggtgccaca gtccaagcta
     2641 tcggtatcgt gattgagaaa tccttccaag atggtcgtga tttgcttgaa aaagcaggct
     2701 accctgtcct atcacttgct cgtttggatc gttttgaaaa tggtcaggtc gtatttaagg
     2761 aggcagatct ctaatgcaaa ctcaagaaaa acactcgcaa gcagccgttc ttggcttgca
     2821 gcacttacta gccatgtact caggatctat cctggttccc atcatgattg cgacagccct
     2881 tggctattca gctgagcagt tgacctacct gatttctaca gatatcttca tgtgtggggt
     2941 ggcaaccttc ctccaactcc aactcaacaa atactttggg attggactcc cagtcgttct
     3001 tggagttgca ttccagtcgg tcgctccctt gattatgatt gggcaaagcc atggtagtgg
     3061 cgctatgttt ggtgccctta tcgcatctgg gatttacgtg gttcttgttt caggcatctt
     3121 ctcaaaagta gccaatctct tcccatctat cgtaacagga tctgttatta ccacgattgg
     3181 tttaaccttg atccctgtcg ctattggaaa tatgggaaat aacgttccag agccaactgg
     3241 tcaaagtctc ttgcttgcag ctattactgt tctgattatc ctcttgatca acatctttac
     3301 caaaggattt atcaagtcta tctctatttt gattggtctg gttgttggaa ctgccattgc
     3361 tgctactatg ggcttggtgg acttctctcc tgttgcggta gctccacttg tccatgtccc
     3421 aactccactc tactttggga tgccaacctt tgaaatctca tctattgtca tgatgtgtat
     3481 catcgcaacg gtgtctatgg ttgagtcaac tggtgtttat ctggccttgt ctgatatcac
     3541 aaaggatcca atcgacagca cgcgccttcg caacggttac cgcgcagaag gtttggccgt
     3601 acttctcgga ggaatcttta acaccttccc ttacaccgga ttttcacaaa acgttggttt
     3661 ggttaaattg tcaggcatca aaaaacgcct gccaatctac tacgcagctg gtttcctggt
     3721 tctccttgga ctgcttccta agtttggtgc ccttgcccaa atcattccaa gctccgtcct
     3781 cggcggtgcc atgctggtga tgtttggttt tgtatctatt caagggatgc aaatcctcgc
     3841 ccgagttgac tttgctaaca atgaacacaa cttccttatc gcagctgttt caatcgctgc
     3901 aggtgtcggt ctcaacaaca gtaatctctt tgtcagcatg ccgacagcct tccaaatgtt
     3961 cttctcaaac ggaatcgtcg tagccagcct actcgccatt gtcctcaatg ccgtattaaa
     4021 tcataaaaag aaataagaaa aagaggtgcg agcctctttt ttgtttatca caaattgatt
     4081 ataaatacaa tcaatcccaa ttcccatcta attgaattgg acctatttca aattctttaa
     4141 aatattatgt tccaaatcgt taatattata taagaatggt aaaatatcaa atgtttctcg
     4201 taaattattc ttagccttat accaaccttg tccatcagta atccacataa actcaacatt
     4261 aggaatagct ttagtttctt cagcaatcat tttgtaagat ctagccgtct catttaattt
     4321 tgaaccactt cctgaataaa aattaacctc aatcagataa agcacttgtt cattttttat
     4381 gacaaaatca aaacgtttca cagtattccc atcattcgta atagcagata aatcgacaga
     4441 aaaaatttcc tctatttcat tttgttcaat ctctttaaat aaattctctc ctaaaatata
     4501 cccttcagct tcaagatagc tttgaacaat attttccatc gcatctccag tccgattttt
     4561 gcgcccatta gtatccatac caacctcaac acctgtaacg tagtcaacta aatttgatac
     4621 taaatgattt tgcaataaat caaatatacc tgatttttcc aaaaacatag tatattcttc
     4681 aatactatag tttcgtttac taaaatcaaa atagaaatct tttatcggat ccttaacaat
     4741 aatcgtatct ctcaaacgtt tagcaataag tagaggcaca actttcaaaa tttctggata
     4801 attttgatat aagtctaaaa aatcctcttg tatattttta ctaccaataa gactattcat
     4861 aatatttaga gcaactttta tactagatac atttttataa accttaggaa aatctgtata
     4921 ataagtccag tcagctactg tgtcggtcat cgttgacaac cactcatcaa aatttctagt
     4981 ttgtttcatt ttctgcctcc aacctcttcc ttgcaatttt taaatattct ttttcagcat
     5041 cgatacctat aaatcttcta cctaaccgct tcgcaacaac acccgtagtg ccactaccaa
     5101 caaatgggtc tagaatatag tcaccctctt tagtagaggc taaaataata cgttctaaca
     5161 aatactctgg tttttgagtt ggatgtttcc cagcccattt ttcaactttc tttgttaaag
     5221 aaccggtcca gacatctttc atttgttttc catcattcaa ttctttcatt aaatcataat
     5281 tgtagtaatg acgagctttt ttatcatttt ttctggccca taaaatggtt tcagtagaat
     5341 gggtaaaata acgacaagat aaattggggg cagggtttgt tttctgccaa gtaatattat
     5401 tcagaatttt aaaaccttct tgttctaatg ccattccaac tgagtatatg ttgtgcaaac
     5461 tacctgaaat ccataccgtc ccattaggct tcagaacttc ttttgctagg cgaatccatt
     5521 tacgattaaa ctcatgtttt tcttcgaatg aagaaatttt atcccaatct cctttatcaa
     5581 cagaaactac ttgtccccca gaattagata ttccaccatt acttaaaaaa taaggtggat
     5641 cagcaaaaat catatccata ctttctggtt tcatttttga taagaacttg aacgtatctg
     5701 aatgaacaag aatcatctta tttttattgt agtatggttt tgtcataaga acacctccat
     5761 acttatattc gttatttttc ataatttgtg actataattt cagaaatttt tcctcgactt
     5821 gaagattttg ctccattagt tcgggtagct tcaacataat gtatattaaa atccttatac
     5881 aactcctcta ctaaagcact agaagaattt gataacataa cataagctcc tgtatcactt
     5941 aatctcttaa agacatctct taatcttact tgatctgcaa aagagaatcc ctcatgagta
     6001 taagacgtaa atgcactcgt ctcagacaat ggaatatatg gagggtcaaa atacacaaaa
     6061 tctcctgttc gaacatctac aattgccttt tcaaaatctc ccactttaat ttctagttga
     6121 ttgttattta gataaactga aatagcagat atcaattcct catcaacaat tttaggattc
     6181 ttataacgtc catatggaac attaaattgg ttcttagaat tcacacgata tagaccatta
     6241 aagttcactc tcaacatata tagaatacgt gcagctcttt gtacttcgga catcatatct
     6301 attctttcat cacgatctgc agaacgtaaa tctaaataat attcttttga attatattcc
     6361 tgatgaactt tcaaaatttc aatcaattct tgaggattgt ccttaatttg ttgatagcaa
     6421 tttattagtt cagcgttaaa atcattaata actgcatctt taggagccaa atcaaaaaat
     6481 aaagctccac ctccaacaaa aggttcgaaa tacctgttat aggttttagg cattaattct
     6541 ctaataacag gcaataattg tcttttacca cctgtccatt tcgtgaacgg ttgtaaagta
     6601 actttcttta tttcttttat cttcatgctt ttaattatac catagaaatt aaaacacaac
     6661 tcttgtattt tctaccacat tactaaattt tctattttag aattaaatca tatcaatatc
     6721 aaaaaatgag taaggcaaat cttataaatt ccaaaattca cctcactcta ttaaattact
     6781 ctttatatcc ttacctgtct ttcttctgac cgctggcctg tgacaaacat ggtaaaggtt
     6841 gctttacaga catttctgcc ctcttgattg gtgatatcca catccatcac acaggttgta
     6901 cggccttgat ggacacattc tcctttaatg gtcaatacat cgtcgagttt tcctgcctta
     6961 aggtagttga tagaggattg gagtgtcacc ccatcaagtc ccagcgagat aaccaccaaa
     7021 ccactgattt ggtcacatag cgtgaataga tagccaccat gggcattgcc atagtagttg
     7081 agcgacgagt tcactacttt ggtcgtcacc acaacgtgac catctctcat tttttcaatt
     7141 tcgtaatttt caaaggcaga tatagcgtca aaatgaaagt ctttcatcgt ttcctcctga
     7201 tatttcaaac gacactatga tactactttt tataggactg tgcaaggaga aagctcctag
     7261 tctagtgaaa ttccgacatg ttccacaaag cgcataaagg ctgtctgccc ttgttctgtc
     7321 tgcttgtaga ctcctgcatc ctcaagtaca cgcacaaaga tagcacccac agagtccttg
     7381 acgattgcaa gggctttttc tttatccgtt aggtctggat gttgggattt gagttggtct
     7441 gcccactcct gatgataatc ggcaactgta acagcttctc ctacaagata gctagcgact
     7501 tgctccactt cttctttcag acgtggtggc aagattgcca agcccatgac ctcaatcaag
     7561 ccgatatttt ccttcttgat atgttggaca tccttgtggg gatgatagat gccatcagga
     7621 tgctctgctg aagtctgatt gtctcgcaag accaagtcca actcaaactg tccatcacgc
     7681 ttacgcgcta ttggtgtgat ggtgtgatgc ggtgtcccgt ctgtctctgc taaaatctgc
     7741 acactagaat ctgaatactg acgccattcc tggaaaatct tatcagctaa gttaatcaaa
     7801 tcctctttgg aatccgaagt caagcgtagg acagacattg gccacttgat aattccagcc
     7861 ttgacctgct caaaaccagc aaatcggaag gtcttttgca agggagccaa ttccatagga
     7921 aatacgtgac ggcctccctg ataatgatca tgagttagaa tagagccccc cacaatcggc
     7981 aggtcggcat tagatccagc aaaatatcct ggaaactgct ctacgatagc caacagacgt
     8041 tcaaaactct gacgactaat ggccatggga cgatgctggc catctaaaaa gatacaatgc
     8101 tcattaaagt aagcataggg cgaatactgg aacccccatt cctgaccaac catttcaaaa
     8161 cggataatcc ggtggttgct gcgagctggg tggttgaccc gaccatggta accctcattc
     8221 tctaaacaaa gttgacactg aggataatta ctagcttgca ccaacttggc taccgcaatc
     8281 tctttcggat ccttttcagg cttagagaga ttgatggtaa tttcaagttc tccataatca
     8341 gatggaacac gataagcgat atttttagca atggccttga gtttgatgta gtcatttttc
     8401 cgactgagtt gataaaaatc ctctatcgct tgctcaggag agtaggcata ggcttcccag
     8461 aagtcacgat tgacctgact cggacaagga gtcaccaagt ccatcagttc agtaccaagg
     8521 atttcacgcg cagtctgact atcctcaatc gtctctaatc gaacggcttc ctcaactagc
     8581 tggtccttga ggtcaatcaa tttatccaga ttggtctcaa cttccaaaac accttctccc
     8641 actcgtgcca aaacacggtt tgtcaggtag attcgatcca tttcctcaaa tgaactttca
     8701 gaaatgacat gtgttacaaa tttatctact aaggtcacta tagagcctcc ttttgactag
     8761 tcaaggacgc gagtgccacc tgcaacttca gcgatataga agcttggagc gtatccaact
     8821 acttcctcgt agtgtttgcc tacagcttcc ttaaaggcct caacagtatc tttttgaacc
     8881 aaggcaatgg cacagccacc aaaaccagcc cctgtcatac gagcaccgag aactccttct
     8941 tgtgcccaag ctgtgtgaac aagagcatcc aattccaaac cagttacttc ataatcacgc
     9001 tccagagaaa cgtgtgacgc attcatcaaa cgaccaaatg tttccaaatc acctgcttga
     9061 agggctgctt gagctttaag ggtacgttgg ttttcaagca cagcatggcg agcacgtttc
     9121 aaacgatttt catctttaat caaatagcta tattggtcaa cggcccactc gtccaattca
     9181 cccagggtct gaatatccaa ggcaacttgc aattcttcca ctgctttttc acactcagca
     9241 cgacgttcat tgtatttaga atccgccaat tcacggcgtt tgttggtgtt catgataaca
     9301 acgacattgt ccttcaaatc aagtggcacc aaatcatact ctaaggtgtt ggtatcaagg
     9361 taaatagcac gttgatcagc ccccatacca atagcaaact ggtccatgat accagagttg
     9421 actccgataa agttattttc tgtttgtttt ccgattttaa ccaaatccaa acgctctaat
     9481 tttaaatcaa agagatgctc tgccactacc cctgtcaaga gctccaagga tgctgaagaa
     9541 gacaaaccag caccatttgg gatattccca taaacataaa aatcaaaacc tttgtcaatc
     9601 acgtgcccag cttcttgcaa gaaatgaagg acaccttttg gataattggt ccagttgtgc
     9661 tctttttcaa acttgaggtc agcgagaggc acttcgataa tgcccttgtc ctcaaagtta
     9721 gctgagtaga aacgcaaaac ttggtcgtca cgcttacgag ctgcaccgta agttcccaag
     9781 gaaatagtag caggaaaaac gtgcccaccg ttgtagtctg tgtgttcacc aatcaaattg
     9841 atacgacctg gtgaaaagaa agtttggtct gcttcttgac caaaaacagc aagaaagtct
     9901 ttgcgaagag tttcagcagt aagatgttgt gtcatatgat ttctcctttg actgtccgtt
     9961 aagccacctt aacgtgtaat cgttttcttc tattgtatcc aaggaatttc ccaaggtcaa
    10021 tcctttttac taaaatttta gtaaaatatc agtaaaaaga agaaaaatat gatatactaa
    10081 cctaatcaag gaggatttat ggctacctta aaagacattg cacagctagc ctctgtctct
    10141 atcgcgaccg tatcccgtgt cctcaaccgc gaccagagcc tatctgttac agaagaaacc
    10201 agacaccgta ttttaaccgt tgctgaagag ctgggctaca ccaagcacct caagacaggc
    10261 gagtcccata aacccaagca aaagattgcc attattcaat gggtcagcga acaaggggag
    10321 ctagacgacc tctactacta ccagattcgc ctaggaatag aaaaaagagc ccaagagttg
    10381 gactacgata tcttgcgcta ctttaatgac caccctttta ccctaagcga ggaagtgatt
    10441 gggattctct gcatcggaaa gtttagtcga gctcagattt ctgcctttga agaataccaa
    10501 aagcctcttg tatttctaga cagcgataca ctttccctgg gacatacctg tattatcacg
    10561 gatttttaca ctgctatgaa acaggttgtc gattatttcc tcagccaagg aatggaccgt
    10621 atcgggattc taacaggcct tgaagaaaca actgaccaag aagaaatcat tgaggataag
    10681 cggctggaaa atttcagaaa ctacagtcaa gcaaaaggaa tctatcatga tgaactgatc
    10741 tttcaaggaa actttactgc ccagtctggc tatgacttga tgaaggaagc cattcagaac
    10801 ttgggagacc aactcccacc agcatttttc gcagccagcg atagtttagc catcggtgcc
    10861 cttcgtgcgc tccaagaagc tggaatcagc ctaccagacc gtgtcagcct catttccttt
    10921 aacgacacca gcctgaccaa gcaggtttat cctcccctct ccagcatcac agtttatact
    10981 gaagaaatgg ggcgagcagg tatggatatt cttaacaagg aagtcctcca cggtcggaaa
    11041 atccctagcc tgaccatgct gggaaccaga ctgacattaa gagaaagtac cctaaatcaa
    11101 gaataggata acataaaaaa cgaatagagt tctaaaactc ctattcgttt tttattcgat
    11161 tacaatcata gacttaattg tcttacgttc atccatatct ttataggctt ggtcgatatc
    11221 ttccagttta taacttgaag taaagacgcg acctggattg atatcaccat caaggacggc
    11281 ttttagtaaa aattgcttat cgtatgttgt agcagaagct gccccacctg ctacagagat
    11341 attttgcata aatgtcgaac caagagcacg attattatag tgtgggactc ctacaaagcc
    11401 catacgccct ccattatgaa gaacacctag cgcctgttct atagcagcct ccgtaccaac
    11461 acattcaagt gctgcatctg ctcctccacc gaggatttca cgcaccttgg taattccttc
    11521 ttgaccacgt tctgcaacaa cagctgtcgc acctgactcc atagccatct tttgacggtc
    11581 ttcatgacgg ctcataagga taatttgtga tgctccacgc atcttagccg cgatgacagc
    11641 acattgacca acagccccat caccgataac aacaaccttg tccccttttt gaacatttgc
    11701 aacacgcgcc gcatgatagc ctgtcggcat gacatctgca agagtcaaaa gggacttgag
    11761 catcccttct gtatagtcag aaggttgacc agggatttta accagcgccc agtttgcata
    11821 gtggaagcga atatattctg cctgaaaatc accccccaaa ttattgccaa tatgattgtc
    11881 gcaagaaccg tcaaatccag caagacaggc atcacactca ccacatccat gtgtaaaagg
    11941 gacaatcaca aaatcacctg gtttcaccgt cgtaatggct tccccagctt cttcaacaat
    12001 cccaatcgct tcgtgtccac tatttttgtg tccagctttc gtttctggat tacggtacct
    12061 ccataaatct gaaccacaaa cgcacgcacg aaccacacga ataatcacat catccgcttc
    12121 tattatttgc ggacgcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt
    12181 aaaattttcc ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta
    12241 gctgagacaa gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct
    12301 ctctcgtttc atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga
    12361 cacccgccga acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat
    12421 cacgaatccc agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc
    12481 gaatcgtatc cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac
    12541 ctcctctcat ttcattcact gaattcacgc tattctaact cacttatctt attatataac
    12601 tttgagttga ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa
    12661 tcatatatct ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa
    12721 taaagaaatt actctattcc aaataagata gtacccaagt atttttcact tttttctaat
    12781 gttgatgctc ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt
    12841 ctaggtcagc atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc
    12901 gaatagactc tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg
    12961 catttttttc caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt
    13021 ccaatcgctc caggccactc tttacttgct tgatatcaag accttctggc acagcatcca
    13081 agaaaatctt gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa
    13141 tgacaaggga caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca
    13201 tcaggataac agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact
    13261 cattctttgt ctttccctta ccaaccacca gactcgctaa catattgata gtaatcgcaa
    13321 taattcctaa ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga
    13381 cattttccaa aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc
    13441 ctagcaggct aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga
    13501 ttgtttctaa aaaagctgat attccaattg caatcgcatc taccaagtca tgcacagagt
    13561 cagcaagaac agcgctagaa ccaaatattc cacctgcaat aaactcaaca atggcataag
    13621 tcaaatttaa gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt
    13681 tgttataata gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa
    13741 ggatagaagc aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat
    13801 gactaacatt gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca
    13861 acttttgaat gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga
    13921 tgtgggacga tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct
    13981 ctgccgctac ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta
    14041 cctcgcccac ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt
    14101 ttccaaaaat gactacttcc tccgtcaact ccagagagag cttgagcacc acgtctattc
    14161 cgtgctagct gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca
    14221 cttggtcatg tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt
    14281 cacagaccag gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata
    14341 gagtaaagct tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa
    14401 aagaggaccc gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt
    14461 tttaatcgaa atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta
    14521 ttctgcttag ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt
    14581 agatatttcc cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg
    14641 gtagccgccc agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc
    14701 ccattggttg catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa
    14761 atgaagccaa aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg
    14821 ccgtccagtt tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc
    14881 caaactagaa gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca
    14941 taaaagcctt tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga
    15001 taattacttg ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa
    15061 atcatcccaa tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa
    15121 cttcctaaaa ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc
    15181 cagatagtct tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg
    15241 taaccacctg acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa
    15301 gtatgcatca tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca
    15361 acgctctatt agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc
    15421 tgaaacccct tatttgttaa gtagttcaca aaatattata catctatttt atgaatagtc
    15481 aagtgtcttt acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta
    15541 agtgacattc agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt
    15601 tatctagtcg tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct
    15661 tcaacaaacc ttgttcttgg agaaactcct tggctacttg ctctgctgac ttgccttcaa
    15721 caccgacttg gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat
    15781 taagaactct ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc
    15841 cttgataagg tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca
    15901 attccgcatc agtcgaatag gcgtccgtaa tttgaatatc acctgactga atagcctgat
    15961 agcgaagggc tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc
    16021 ccttatttcc atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt
    16081 ccactttttt caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa
    16141 cagctacagc ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct
    16201 tagcaatgcc atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg
    16261 atggttgaag caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc
    16321 cttttttcag agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag
    16381 tcatgctggt attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg
    16441 gacctatttt cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac
    16501 tataagacag acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt
    16561 ttgctttttc cattactttt agtaggaagt taaaggcaat agcaagcact gcagaagaaa
    16621 gtgccccaat caaaatcaaa ctggcattat tacggtcaat tcccaacagg ataaaggaac
    16681 ccagtccccc tgctccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg
    16741 ccgtccgaat cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac
    16801 gttcccatct ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct
    16861 tcagcccagt gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca
    16921 aagccggcaa ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg
    16981 ggatggtctg gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc
    17041 gaagaaaaac agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagtgaca
    17101 actgcaaatg ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa
    17161 ttaaattagt catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcact
    17221 tttaaaattg tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata
    17281 cggtccgcca acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca
    17341 aactctttat gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag
    17401 gccgaaaagg gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata
    17461 ccgacccgtt gctgttctcc accagataat tcactaggta agcgatgccc atactcggct
    17521 actggtaaac caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc
    17581 caccccttca tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga
    17641 gcaatagcct gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg
    17701 atgcgcttcc catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc
    17761 ttgagcatgg tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc
    17821 tcaatctgta agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt
    17881 ttgtattcaa tcattctttg tcctcaattt aaaacttccc tcgattagtc aagtcttcta
    17941 ccttaggcat gacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga
    18001 agatatcgta ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat
    18061 agtttccttg tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat
    18121 agtttttata agcagcactt ccttgtccaa tctcatgatt atgctgaatc aaatcgtctg
    18181 ccacataatc actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc
    18241 gaaccagctt tttattttct gctttcttat ccaaatcctt gatttcaaaa tctccaaaaa
    18301 tttgatctag ttggtcattt tcaggtgttc gatagtagtc aatgacatcc caatgctcaa
    18361 caatacaacc attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac
    18421 cattcagata ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa
    18481 tcttaatctg acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt
    18541 ctttcccgtc aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt
    18601 gagcctcagc aactcgtccg tcttgaatgg catggatgta taggttgtga gcatttttca
    18661 cttgttgtga catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt
    18721 cttgaaaacc ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat
    18781 ccaatttctg actgacacga tgccccactt ctttctggga cttgcctaac tccgttaaaa
    18841 ctaaatactt cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct
    18901 ctagcttttt tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat
    18961 ctgtcgcagt tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt
    19021 cacccctata aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca
    19081 acaaacgaat atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg
    19141 atgtcgaaat gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt
    19201 tggaaataat ttttgataat tattcacacc accatactcc ggctcaacta acttttaacg
    19261 agagtttcta aattccttcg tcctccagtc tacaaaagcc ttccatccgt actatcctat
    19321 tttttatgag gggacacatt tttcctatca gatcatttat tttaaagata gaagtaaatc
    19381 ataattgctt ccatctgttc ttttatagta tattgaagtt ggactagggc actgtatctt
    19441 ctaaaacatt gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat
    19501 tttgaaacta gaataggacg ccatgactgc taaaagattt ctataaattc atttgatttt
    19561 cctaatcaat ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt
    19621 ttcgtagcac ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcactcca
    19681 cttccattac agaagtttct tcactactat ggtctcggct gacttctcat gattccttgt
    19741 tactactatt tgaacgctca cgagataggt cttataaaaa atgctttgat ccacaatgga
    19801 atcaaagcat tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact
    19861 tggcttcttc tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg
    19921 gatttaggag caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat
    19981 ttgtagtagg cagtttttta gtagtctcta ggagagcagc aactaaatct tcactcaaat
    20041 catgtcgagc atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc
    20101 ctaccacctc ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt
    20161 tcttcaccaa ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg
    20221 tttggtgaga atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat
    20281 ttttcagatg agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga
    20341 taccagcttc ttcagccgtt gtcaaaagga aatccttcat ccctgggaga agcaagtgac
    20401 ctggatcata gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat
    20461 cacctgctgg tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg
    20521 tatgagcgcc acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc
    20581 cgagtttttg acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt
    20641 tatcccaagc ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg
    20701 gtacgatggt atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac
    20761 caccatcaaa aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca
    20821 aatgcggagg aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt
    20881 tgaaacgttg gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg
    20941 taccatctag cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca
    21001 agacgcgcgg tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat
    21061 ctgtcaccac ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg
    21121 cttcatgacc tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg
    21181 tcatttcagt tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg
    21241 ggaaggtgga tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt
    21301 ctcttgcatg tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc
    21361 aaacaaaaaa acaatacacc atcaaagttg tttagatttt tcatgaaatt tacagaaaat
    21421 agttgacttc cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc
    21481 tgtagctgct aaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc
    21541 ttatttcaat ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc
    21601 ttgttacagg tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg
    21661 gctatcaggt gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc
    21721 gtgctagctt taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag
    21781 aaaatcagat tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg
    21841 aaaatccaag taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct
    21901 tatctgaagt tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata
    21961 actgtattga caagccggtg actgaagata ccctgctcga ccctgtcaac ccttatgcag
    22021 agacaaaact gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat
    22081 atgttatttt ccgttacttt aatgcttctg gggctgaaat ggatgcttca aacggtctgc
    22141 gtgtgaaaaa tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg
    22201 atagcttaaa aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt
    22261 acatttatgt cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag
    22321 aagacagttc ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa
    22381 tctttaaaac tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac
    22441 gtgctagtga cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt
    22501 ggacggctag ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag
    22561 aataggataa caaaggagaa agtcttgttg ctctctcctt gttatattta ttaaattgtc
    22621 agaaatttta ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg
    22681 ataccaaatc tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact
    22741 tctactccta gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct
    22801 atttgatttc gaccagcaga cctggctcct ttttcaagag tcccgtctcc caagaactat
    22861 cagtattctc ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac
    22921 ccaaaatcag tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat
    22981 ggtgctgagc ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt
    23041 tgtttcatcc atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa
    23101 ggaaaggtgg gtgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac
    23161 agaagttatc gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc
    23221 cttctccatg attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat
    23281 aaccgtttgg aaattatccc aaaccttcac catcatgaat ctagggaaag aaaccagcga
    23341 gagtttgggg atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac
    23401 gacaagcgtc accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa
    23461 tcttgttcgc aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt
    23521 tggtgccaat ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga
    23581 gttgtctgtc agtctcttgc taggaatcat cggtagtctc gtctttatcc tacttctctg
    23641 gagaggggga cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca
    23701 ttattcttgc catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct
    23761 ttgcttggaa gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg
    23821 ggatttcgac cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt
    23881 tgggaattga atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt
    23941 ttcttcaact tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc
    24001 tcttctttct cgccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca
    24061 tcctgctgaa ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag
    24121 tcctaatgga tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac
    24181 atctcaacac ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt
    24241 tctttcgaaa agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat
    24301 tgggactcga tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct
    24361 caacggccac tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca
    24421 cctacctgat tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg
    24481 gatttattag cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc
    24541 gtatcagtat gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga
    24601 ggtctcgtca gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca
    24661 aggcatttcg cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc
    24721 tggaaaatcg actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct
    24781 cagtatcaaa ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac
    24841 catcctaaaa cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt
    24901 tggacgtttt ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga
    24961 aactctgaac tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg
    25021 ggggcaactc cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt
    25081 gctggacgaa ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct
    25141 tcgacgactg gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat
    25201 ggccagtcag tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg
    25261 aagaaccgat caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac
    25321 gctagctgat atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag
    25381 ttagagaacc ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca
    25441 ttttaaaaag gagaaattat gaaaacatcc cttaaacttt atttcattgc cctagtggcc
    25501 agtttcttgc tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagccc
    25561 agtagctctg ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc
    25621 aaagttcctg aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta
    25681 ggatttgaaa aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac
    25741 ctagtgggaa ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc
    25801 gcccttgaac ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc
    25861 aaagaaatcg ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc
    25921 aaggctaata tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca aaaagccaag
    25981 gaagaattgg ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct
    26041 gacaaaaaag cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa
    26101 tctcgtttct ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa
    26161 gactcacgcc acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgacatc
    26221 ctctttgtca tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc
    26281 ctagaaaatg cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta
    26341 acaccagacc tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa
    26401 gacatacaaa aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc
    26461 aaagagcaaa ctagaaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat
    26521 gaaagctgac gcggtttgaa gagattttcg aagagtataa aattttgaca ttctaaaacg
    26581 catcctatca agtttattca aacctgatag gatgcgtttt tatcattttg aaatctattt
    26641 accccacctc attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc
    26701 ttacctgttt tcgaccaggg atgacaacgt aaaatccgag ccaagctcat caataccccc
    26761 ttaaaaccat gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga
    26821 caagagggtg gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa
    26881 attcgtttca ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat
    26941 taagacgacg ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc
    27001 gagacaactt atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac
    27061 gcccttcatg gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa
    27121 tttcataaac agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc
    27181 gaagattgtc cttattggcc acacctttaa cacgcgcgac ataaaccttg tcaatctcat
    27241 tacgagggtg aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagactcctg
    27301 atgtatccca gtccaaacga cccacagggt aaatgcgctc tttgacattg ggcaagaggt
    27361 cgacaaccgt cttgcgaccc ttgtcatctg ttacactgga aatgacaccg cgtggtttgt
    27421 taagcagata atagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt
    27481 cgcctgactt gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaaac
    27541 cttgcttgat cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact
    27601 tattgattct catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc
    27661 tcaagctcat caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa
    27721 taatccgtag tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt
    27781 atcaggtcaa aagcttgcaa ctttgccaag gctccactcg agttaacccc acggatggca
    27841 tcaatttcta tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca
    27901 gcccgagaca agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat
    27961 tgaggcttgg tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct
    28021 gggtcctttt catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc
    28081 agagagagga gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag
    28141 agcgcttcta tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc
    28201 acttgacttt cttccttctt ttccatgaga tagatatctc cgaaactctc ctcttgcacg
    28261 aggatcagct cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct
    28321 tggacattct gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag
    28381 gactctttca cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg
    28441 tgattttgtg caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg
    28501 tcaatggtcg tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct
    28561 ttggaataat actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg
    28621 aacttgcgat attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct
    28681 gtcacttctg ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc
    28741 atgaccatgt actcacccgt cacttccaga cgcatggcct gcagggttga gacataggct
    28801 agatactgtt cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa
    28861 accagatgca agagcaagtc caggggtcct tcaaaatctt ttaatttaat atccattatc
    28921 tatatttttc taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat
    28981 cgaccttgtt ttctatttgt cttaaaataa actgttcacg taagacttga gctgataagg
    29041 atggaaaacc tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat
    29101 agggtttccc tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa
    29161 gcaaggccgt gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct
    29221 gaaaatccag attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca
    29281 tttctaggat taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag
    29341 agtctaggta tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca
    29401 agcggtaaaa gctgtccacc tctccttttt gatagagaaa gtagagaaat tggttacagg
    29461 ccgaaatctt tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct
    29521 tgagactggt ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact
    29581 tataggactg cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc
    29641 tgtctctcat tggcatcgaa tctcatattc cttactaaaa tcatgcaaga gggcattaac
    29701 ggccttgagg atggacttgc gcgtaataat cccttggaaa ataccctctg tatccacaac
    29761 cggtaagaag gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga
    29821 aacaaccgct acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg
    29881 gctcaagtca tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa
    29941 ctgtttttca tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt
    30001 cgcatgatcc gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa
    30061 agtttcctcc tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc
    30121 ttggacaaac ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta
    30181 tcatcaatct ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata
    30241 gaacctggat ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga
    30301 ccatagaggc agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg
    30361 aaattgatgt caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc
    30421 accagacgtt ctgggtagcc ggcgtagaag tccatgttcc ctttaacaac gcggatgccc
    30481 tcccaaagtg gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact
    30541 ttgcccacat agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc
    30601 attacaatga tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta
    30661 aggcacggtg agattgacta tttttttctt ccagggttaa ttcagctgat gactcacctg
    30721 tctctcctac aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt
    30781 taatataacc tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga
    30841 ctagggttgt gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt
    30901 gcaagagttt ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc
    30961 agacgcctgg taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca
    31021 tcttgcccgt taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca
    31081 tacctgtttc tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc
    31141 ctaacttatc aaagatagct cggaattcct tggttttacc ttcgttacga gtcgcaatca
    31201 acaaggtttc tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag
    31261 gcaattctac atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa
    31321 taacttccaa gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac
    31381 ggtaggtaga accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc
    31441 caaatatttt ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa
    31501 cgccaccaaa aatactataa gacccaacat accagtcctg gtcatcctta tattcataaa
    31561 ttttatttgt cataattcta catgctccac atgaatctct ttttccagcc attcttcacc
    31621 aatttgtgca aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc
    31681 atcgcgacca cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc
    31741 tgccccacta tcgatgagct gaacctttgg ccccatcaca ttttggataa tagggcgaag
    31801 gagtggataa tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag
    31861 ggtttcatag accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg
    31921 agcaaacttg ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt
    31981 ctgacggtat atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc
    32041 ttgactggac ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc
    32101 tagttgagcc ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat
    32161 cattttgaca tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg
    32221 ctcagcagga cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc
    32281 atggggaagc tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa
    32341 aaaaccaatt ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt
    32401 tcattatgat tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct
    32461 ctctcttaat cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca
    32521 taaccaacat agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc
    32581 tttttattgt tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt
    32641 accttagctt cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca
    32701 ttcaaacgtg ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct
    32761 ccaagagctc ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc
    32821 atttttctcc tgtttctttt tgaatccctt tcattatacc acaaactagc caccctgacc
    32881 agtttgttct acactttcaa ggatggaata gacagcaaaa agaaccctgc ttttctgaaa
    32941 aagaggtctc cttgctaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    33001 ccacaggttg ctcaaagcac cgctttgagg ttacagataa aactgacacg gtttgaagag
    33061 attttcgaag agtattaatt tacataaata gccagtgttt gatagggttt gagtagaatt
    33121 ttctcagaca cttctgcatc ttcatagttt gaaatcaaaa tctgtccatt ttggtagact
    33181 gctggcaagt cgatttccac ttctttggca taaaagttat tgagcactag taacttttga
    33241 tcctcaaact ggcgttcaaa agcgtagact tgtttgctat cttcaaaggc tggtttgtaa
    33301 tttccttctg aaatgattgg catttcctta cgcagtcgaa tcaagtcttg atagaaggtg
    33361 aaaatcagac ctttgatttc attttctaca ttgatatctt tataggattt accgactttc
    33421 aaccatggag tgcctgttga aaatcctgca ttttcagaag tatcccactg catgggaata
    33481 cgtgaattat cacgcgactt agcttgaata atctggaagg cctcttgctg actctttcct
    33541 tcttctaaga gcatctgata ggcattaagc gattcgacat ccacataatc agccatagaa
    33601 tcatagtctg ggtcaatcat cccgatttcc tcacccatgt agatataagg tgtcccacgt
    33661 gacaggtgaa tgctggctgc tagcatggtg gctccttcct tgcggaagtt ttgaatatcg
    33721 acaaaacggt tcaaggcacg tggttgatcg tgattgttcc aaaagagggc actccaaccg
    33781 tctttatcac tcatttcctt accccaacta tggtaaagac tcttcaactc ttcaaaatca
    33841 aagggagcca aggtccactt ttgtccatcc ttatagtcca ccttgaggtg atgaaaatta
    33901 aaggtcatgg ataattcctg acgatcaggc gacgaataaa ggacacagtt ttccatggtg
    33961 gtagaagaca tttccccaac tgtcataaag ctatcgtcag atccaaaagt ggcttggttc
    34021 atcatacgca aatagttatg aacgatgggt ttgtctgtat aagctggctt cccttcattt
    34081 tcaggacagt ccactgaaac ctcgtcctta ccgatcaaat tgatcacatc aaatcgaaaa
    34141 cctttgacac ccttgtcgcg ccagaaatta acaaccttga aaagctcctt acggacattg
    34201 ggattgcgcc agttaaggtc agcctgggtc tcatcaaata ggtgaagata gtatttccca
    34261 gtatccccga aaggcgccca tgcagaacca ccaaacttag actgccaatc tgttggttgg
    34321 tcttggatga agaaaaagtc ttgataatac ttatcaccag ctagggcttt ctgaaaccat
    34381 tcatgctctg tcgaacaatg attaagtacc atgtccagca taaagtcaat cttgtgctct
    34441 ttaccgacac acaccatttc ctcaaaatca gccatatcac caaaaagagg atccactgcc
    34501 atataatctg aaatatcgta accattatcc cgttgagggc ttggatagaa tggattgagc
    34561 cagaccatat ccacacctag tttggctaaa tagggaattt tttcgataat cccacggaaa
    34621 tccccaatac cgttttcagt ggtgtctttg taagattttg gatagatttg atagactact
    34681 tttcctttat caagtgtcat ctgtttctcc ttttctgata aaagggagga agcagtcttc
    34741 cgtccctatt tgtgctattt caattatact caatgaaaat caaagaacaa actaggaagc
    34801 tagccacagg ttgctcaaaa cactattttg aggttgcaga tagagctgac gtggtttgaa
    34861 gagattttcg aagagtatta gattcgtgta gcgaccatga gagatgctcc agcttggatc
    34921 gttgtcggat aagttccagt aatagtcgct gtataagcat cttggttggt gatgataaca
    34981 ggagtttctg tcaccagacc tgcagcctta atgacatcca tatcaaaacg aatcagttgc
    35041 tggccaacta taacgtgatc tccttggact acaagacttt caaaaccttt gccatcaaga
    35101 cctactgtat ccataccgat gtggatgagc aattcaactc cctcgtcaga gacaatgccg
    35161 atggcatgct tggtagggaa aagaaccgtc actgttccat taactggaga ggtcaactca
    35221 ccttggcttg gttcaatgac cagaccttgc cccatgacac ctgatgcaaa aacaggatcc
    35281 gtcgcttgac tcaattcttt cacttggcca gttagtgggc tgataatttc taccgaagta
    35341 agttctactg gttcatggct cacaaattct gcttcttctt gagcaacgaa ttctgcctgc
    35401 aagttcgtat cgccctctat ttttgtgaag agaccagcct tgcgaaagaa gaaagtcaag
    35461 agcattggaa caacaatcgc aactagcata gttcctgcaa atggcagcat gtattgaggt
    35521 tgaatagaga gaatacctgg caaaccaccg ataccaatag aagccgcagt tacattaaaa
    35581 gtaacggata acatgcctgc aagggctgaa ccagtcatcc cagcaacaaa tggataaata
    35641 tattttacgt taaccccaaa aagagctggt tctgtaacac cgagataggc tgaaatggtt
    35701 gcaggaagtg aaacctgagc ctcacgctca tcatggcgat gcatgaaata ataggcaaac
    35761 acggctgagc cttgagcaat attagaaaga gcaatcattg gccatagggc agtgccacca
    35821 gcatccgcaa tcaattgtgt atcaatggca ttggtcatat ggtgcagacc tgtgatgaca
    35881 aatggagcgt agagggcacc aaaaattgca ccgaagagcc atttaactgg accagttaaa
    35941 cctgccaaga caactgatga aagtccttgt ccaattgtcc aaccgattgg tcccaaaaca
    36001 gtatgagcca aaatcaaggc tggaatcaat gacaagaaag gtacaaaaat catagaaatg
    36061 acttctggga tatgcttgcg ccagaagatt tcaagataag acagactcaa acctgcaagc
    36121 aaggctggga taacttgggc ttggtaaccg atacgattaa tagtaaaata gccaaaattc
    36181 caaacccagt ttgccgcgat atcagctgct ggcgttgaag caaccgcata ggcattgagc
    36241 aactgaggcg ataccaaaca gattccgaga acaattccca aaatttggct ggttcccatc
    36301 ttacgagaaa cagaccaagt aatccctact ggtaagaact ggaagatagc ttcaccaggc
    36361 aaccagagga agtgattaac ccctgcccaa aactgagagg attctgtgat ggtcttgcca
    36421 tccaacatcg accaatggac accttccaag acattacgga aaccgaggat caatccacca
    36481 acaatcaagg ctggaataat cggagtaaag atttccgcca gagtggtcat aacacgttgg
    36541 accacgtttt gattactctt agctgcagac ttggctgctt ctttggaaac accctcaata
    36601 cctgaaacgg ctgtaaaatc attataaaag atgggcacgt catttccaat gattacctga
    36661 aattgacctg catttgtaaa ggttccttta acagctggaa ttgactcgat agctttaaca
    36721 ttagccttct tatcatctcc taaaacaaac cgcatccgtg tcgcacagtg agttacggca
    36781 gtcacatttt ctttgcctcc gattgcctga agcagatctt tggcttcttg ttcaaatttt
    36841 cccatttgat tctccttata cttgtcaaag caagtttgat ttgataagta tattgtaaac
    36901 gataccaaac ttgtctgcaa cttgtttggt ataaaaaggg tgtttttttg taaattttct
    36961 agcacttgta tggtaaaata gatacaggtg ttcattaaac tagactaaaa acctatttaa
    37021 gcaggcaaaa tgaagaaata ccaacaatta tttaagcaaa tccaagaaac cattcaaaac
    37081 gagacttacg ctgtcggaga tttccttcct agcgagcacg accttatgga gcaatatcaa
    37141 gtgagtcgtg ataccgtccg aaaggccctg tctctcctcc aagaggaagg attgatcaaa
    37201 aagataagag ggcaaggttc tcaagtcgtc aaagaagaaa ccgtcaattt ccctgtatcc
    37261 aacctaacca gctaccaaga actagttaaa gaacttggac tgcgctctaa aaccaacgtg
    37321 gtcagtctgg acaagattat tattgataaa aaatcctcac tgataaccgg tttcccagag
    37381 tttcggatgg tttggaaggt gggccgccag cgtgtggtgg atgatctggt atccgttctg
    37441 gatacggact atctggatat ggaactcatc ccaaatctca ctcgccaaat tgctgagcag
    37501 tctatctatt cttatataga aaatggcctc aaactcctta ttgattatgc tcagaaggaa
    37561 atcaccattg accactcaag cgaccgagac aagattctca tggacattgg caaagaccct
    37621 tatgtcgttt cgattaaatc aaaagtctat ctccaagacg gacgccaatt tcagtttacc
    37681 gaaagtcgcc ataagttaga gaaatttaga tttgtagatt ttgcaaaacg caagaaataa
    37741 aagactgaga caccagatct cagccttttt cggctctata atatttgtag tgggtaaatc
    37801 ccttatagat attatggagc ctattttgtt atagaaaaaa agtcccatat gacctataat
    37861 gaaaagcgac aaaaccatca ttagaaagat tcatatggaa caattacatt ttatcacaaa
    37921 actgctcgat attaaagacc caaacatcaa gattctagat atcatcaata tggataccca
    37981 caaagaaatt atcgctaagc tggattatga ggctccatct tgccctgatt gtggaagtct
    38041 aatgaagaaa tatgactttc aaaaaccgtc taagatccct tacctcgaaa caactggtat
    38101 gccttctaga attctcctta gaaaacgccg tttcaagtgc tatcactgtt caaaaatgat
    38161 ggttgctgag actcccctgg taaagaaaaa tcaccaaatc cctcgtatca tcaaccaaaa
    38221 aattgctcaa aagttaattg aaaaaatgtc tatgactgat attgcccatc agctttccat
    38281 ttcaacttca actgtcattc gcaagctcaa tgactttcac tttgagcatg atttttctcg
    38341 gcttccaaag attatgtctt gggatgagta tgccttcact aagggaaaga tgagtttcat
    38401 tgcgcaagat tttgataatc ttaatattat cactgttctt gaaggcagaa cacaagctgt
    38461 catccgaaat cactttcttc gctacgatag agccgttcgt tgtcaagtga aaatcattac
    38521 gatggatatg tttagtcctt actatgactt ggctaaacag
//
LOCUS       DAVDHZ010000017        38391 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000017 DAVDHZ010000000
VERSION     DAVDHZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38391
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.017"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(826..1398)
                     /locus_tag="VUR46_001044"
     CDS             complement(826..1398)
                     /locus_tag="VUR46_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456486.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIHSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGNWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(2021..2869)
                     /locus_tag="VUR46_001045"
     CDS             complement(2021..2869)
                     /locus_tag="VUR46_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5456487.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            3021..3299
                     /locus_tag="VUR46_001046"
     CDS             3021..3299
                     /locus_tag="VUR46_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456488.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            3301..5364
                     /locus_tag="VUR46_001047"
     CDS             3301..5364
                     /locus_tag="VUR46_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET5456489.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRLLQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(5442..6698)
                     /locus_tag="VUR46_001048"
     CDS             complement(5442..6698)
                     /locus_tag="VUR46_001048"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET5456490.1"
                     /translation="MHIFDELKDRGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            6840..9302
                     /locus_tag="VUR46_001049"
     CDS             6840..9302
                     /locus_tag="VUR46_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET5456491.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYYQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            9367..10278
                     /locus_tag="VUR46_001050"
     CDS             9367..10278
                     /locus_tag="VUR46_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET5456492.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            10508..11206
                     /gene="dapD"
                     /locus_tag="VUR46_001051"
     CDS             10508..11206
                     /gene="dapD"
                     /locus_tag="VUR46_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET5456493.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            11274..12404
                     /locus_tag="VUR46_001052"
     CDS             11274..12404
                     /locus_tag="VUR46_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET5456494.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVDAVSSFLKKKAAE"
     gene            12416..12955
                     /locus_tag="VUR46_001053"
     CDS             12416..12955
                     /locus_tag="VUR46_001053"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET5456495.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            12939..13616
                     /locus_tag="VUR46_001054"
     CDS             12939..13616
                     /locus_tag="VUR46_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET5456496.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(13683..14582)
                     /gene="galU"
                     /locus_tag="VUR46_001055"
     CDS             complement(13683..14582)
                     /gene="galU"
                     /locus_tag="VUR46_001055"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET5456497.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(14604..15620)
                     /locus_tag="VUR46_001056"
     CDS             complement(14604..15620)
                     /locus_tag="VUR46_001056"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET5456498.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            15832..16271
                     /locus_tag="VUR46_001057"
                     /pseudo
     CDS             15832..16271
                     /locus_tag="VUR46_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(16386..16811)
                     /locus_tag="VUR46_001058"
     CDS             complement(16386..16811)
                     /locus_tag="VUR46_001058"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5456499.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(16879..17529)
                     /gene="phoU"
                     /locus_tag="VUR46_001059"
     CDS             complement(16879..17529)
                     /gene="phoU"
                     /locus_tag="VUR46_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET5456500.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELACARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(17544..18296)
                     /gene="pstB"
                     /locus_tag="VUR46_001060"
     CDS             complement(17544..18296)
                     /gene="pstB"
                     /locus_tag="VUR46_001060"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5456501.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(18298..19113)
                     /gene="pstA"
                     /locus_tag="VUR46_001061"
     CDS             complement(18298..19113)
                     /gene="pstA"
                     /locus_tag="VUR46_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET5456502.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLVIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(19106..19969)
                     /gene="pstC"
                     /locus_tag="VUR46_001062"
     CDS             complement(19106..19969)
                     /gene="pstC"
                     /locus_tag="VUR46_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET5456503.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(20087..20962)
                     /locus_tag="VUR46_001063"
     CDS             complement(20087..20962)
                     /locus_tag="VUR46_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HET5456504.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(21129..22460)
                     /locus_tag="VUR46_001064"
     CDS             complement(21129..22460)
                     /locus_tag="VUR46_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET5456505.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(22461..23168)
                     /locus_tag="VUR46_001065"
     CDS             complement(22461..23168)
                     /locus_tag="VUR46_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456506.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(23252..23554)
                     /locus_tag="VUR46_001066"
     CDS             complement(23252..23554)
                     /locus_tag="VUR46_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET5456507.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(23541..23762)
                     /locus_tag="VUR46_001067"
     CDS             complement(23541..23762)
                     /locus_tag="VUR46_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET5456508.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            23724..24282
                     /locus_tag="VUR46_001068"
                     /pseudo
     CDS             23724..24282
                     /locus_tag="VUR46_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(24672..26363)
                     /locus_tag="VUR46_001069"
     CDS             complement(24672..26363)
                     /locus_tag="VUR46_001069"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET5456509.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILNLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIATELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKAQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            26499..26945
                     /gene="argR"
                     /locus_tag="VUR46_001070"
     CDS             26499..26945
                     /gene="argR"
                     /locus_tag="VUR46_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5456510.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLANETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            26996..29530
                     /gene="mutS"
                     /locus_tag="VUR46_001071"
     CDS             26996..29530
                     /gene="mutS"
                     /locus_tag="VUR46_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET5456511.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIREILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREESA
                     NLEYEIFMRIREEVGKYIQRLQSLAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IQKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAETAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIESGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            29677..31371
                     /gene="patA"
                     /locus_tag="VUR46_001072"
     CDS             29677..31371
                     /gene="patA"
                     /locus_tag="VUR46_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET5456512.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNFYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQTIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAVKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(31700..31963)
                     /locus_tag="VUR46_001073"
                     /pseudo
     CDS             complement(31700..31963)
                     /locus_tag="VUR46_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            32160..33926
                     /gene="patB"
                     /locus_tag="VUR46_001074"
     CDS             32160..33926
                     /gene="patB"
                     /locus_tag="VUR46_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET5456513.1"
                     /translation="MKTVQFFWNYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNVVLYIGLILV
                     MFSRNVTLALITIASTPLAFFMLIFIVKMARKSTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLVNTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            34065..34754
                     /locus_tag="VUR46_001075"
     CDS             34065..34754
                     /locus_tag="VUR46_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET5456514.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPLGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            34758..34937
                     /locus_tag="VUR46_001076"
                     /pseudo
     CDS             34758..34937
                     /locus_tag="VUR46_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34924..36273
                     /locus_tag="VUR46_001077"
     CDS             34924..36273
                     /locus_tag="VUR46_001077"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET5456515.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLIVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANSWVTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKSLMEGANTARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            36397..37857
                     /locus_tag="VUR46_001078"
     CDS             36397..37857
                     /locus_tag="VUR46_001078"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET5456516.1"
                     /translation="MLKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGVTPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     TDLETIFQMAKPFLEEAGCLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            37871..38305
                     /locus_tag="VUR46_001079"
     CDS             37871..38305
                     /locus_tag="VUR46_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET5456517.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAIPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        11232 a         7290 c         8330 g        11539 t
ORIGIN      
        1 tcctagatac agtgaaggct ttaaatgctg gtttttgctg tcttcagcct tatatttttt
       61 cgtagttggt tacctcatat ctcttgtatt cgcttacata aagtattata atataattgt
      121 aggaaagaag gtgtttttat gatatacaca cttaaattgg tgttgtttat tacctttctt
      181 gtaataagct tgttacctga taagattttt ggaaaaaata aaaaaatttg gaaaatagtt
      241 tttgcaatat tgacggcagt ggcagcattg tcatttatgt actaagttat tttaagaatg
      301 tagggaaata aaccctacat tctttttagt tttttctgtt ttctaaattc tatttatcca
      361 agcgcttcaa catttcttgc ttcttcgctt caagttctgc acgcttttct tcgatttcgg
      421 catgtttttt ctcgagttca gaacaacttg caccattgct aaattctttt cgccatcagg
      481 agatagggtg agtcgacatg tctattactc acccaaagca gtcctacaaa gcaggaattt
      541 tctgttactt ttttggaaat agtaacgttt atacagcttt gacacttcgt atcaaagcgc
      601 caaacacact ccgagggatt tacagaaagc agaaaaggaa tgatctggta taagatcatt
      661 ccttttctct ctttttcttt aagtaattat atacaatgta cgacgaagtc gtcattgcaa
      721 tgctgatcca ccacctaaag ggaactttaa acaacattga taagataaag aatataaaca
      781 acgaaaatac gttataccca attaatttta ttgtatatct catgattaaa agttaatcct
      841 tccgttgtta ggaatggcat catttttatc ccataattgt gctaaataag tccccggtga
      901 taataaattc atagcggatt ctaaagcaac atcatttaca aaccaattac ctagatatct
      961 agaaattgct gaacgaatag cactttttgc tgcatgtttt ccttttactt taattagatt
     1021 tgcaaggcct gcagtagttc ctcctaatgc taaagctatt gcagtatcta atagagcacc
     1081 catttgatta actgtaatac cttgccaagc tgctctaaat ggagagtatg taggtgggat
     1141 tgtataatcg ccttgtaatt gtcggttaat tacttctttg atccattgtt gtgagacgtc
     1201 tggatgaaaa gagtggattt cgtttgcaag tgtattgatt tgttcttctg ttagagaagt
     1261 gacaggttga agttccatat ttgtttcaat ttgtgatact tgttcagaag cgtatacagc
     1321 tgaaacactt ggaatcgctg atacaattaa cacaattgac gtcaaaaaaa ccgaaataaa
     1381 tttcattaat ttgttcatga gcttttctcc tttttatttg tatctgctta cattttatta
     1441 tatactgtta ttatagtcaa gaaaaatatg ctattatgtt aaaaaaatat ttttaaaaat
     1501 ataaatggac ggatttattt tggattttat ttgttatttt gacctgcctc tatattggta
     1561 accatgattt gtttactttc aatcatcaag aattctcttt tcgtggtagc gtttggggtc
     1621 tggtactggc cttatatcac ttattgttca ttgataagtt tgtaatttcg aatcgaaaat
     1681 aaagattaga actatgattg actggctact tttaatattg attttggagg aagattttgt
     1741 ctctattatt tattatttta aatttattta ttttgtataa gatctattct ttgaggcggg
     1801 aaaaatcgaa atacttgatt tatacggcct atatcatatt tggggtaaat gtagtatatg
     1861 gtattcaatg gttattaaga gaactgattt caactatttc cccttaatgt gtatggaaac
     1921 tataacaaaa cgcataagat taaggtttgt gtacctgttc ttatgcgttt ttataatatt
     1981 gaagattttc ggtaagtttt atacctttgg gaagtctagt ttagaatgct ttcccaacca
     2041 aaatctctgc ttcgatggta atctctgtca gttggctcca gtcaatcttg ctctggtcaa
     2101 cgtgaaagag gagaggagtc atactgagta gggcttggag ttgttctgct gtgatagtct
     2161 tagtcagaga ggcagtttga ctagatagga tggtaaagtg ttcctggaaa tgctccttga
     2221 tatcttggtt agaatactcc ttgtttgtca gctggtcctg tactctttga cggatttctt
     2281 tgaggtgatt ttcagttggg ataaccttta tcaagatacc gtctttggat aaaacgcgac
     2341 gaaattctcc atagttggca ggtgagaaga tatcaagcag aatatccatg ttagcgtctt
     2401 ttataggaag tcgtgccaag tcgccaacaa accaattgac tgcccagttg ggttcacttt
     2461 tagcagcgat ttggactgaa tctttggaga tgtcaaaggc atagaaagtt ttttcagagt
     2521 gactttcttg tagtttgcga gaatagaatc cttcaccaca accgatatcc aaaattgttg
     2581 tggtagtttt tgagcttgca agcaagtcag atacagcatc taagatagct tggtaaaagc
     2641 cggcttctag gatttgttga cggttttgaa aattttcctt gttatagtta gcagattgct
     2701 tgatttgagg tgctagattg acatagccaa atttcgccaa gtcaaaagaa tgacggttgc
     2761 agcacttgaa attagtctct aacagagtca gattttcttg acagatagga caggcaaagg
     2821 cagtcgcaga agcaaaacgc tgaagtttgg gcttgagatt tgtattcata gtttaagtgt
     2881 atcaaaagag gcaaatgaaa gcaactttag gaataagtag atgggagatt cagtagaaat
     2941 aaaactaatt ctccaattta tagaatgaaa ttgcttttat atctaaattg ctatataata
     3001 atgataagga ggaaataagt atgttaaaag aagtattaac cgttgcaaaa gttgcgaaaa
     3061 aatcttcatt atttttgggt ggtgtcgcat ttggtaccct tggtttgaaa atcttagcaa
     3121 gtaaggaagc taaaaaaggt tattctaaag ctttggctaa ggcttacaag ttgaaagacg
     3181 agctagatgc atctgtttct gttgtgaagc aacatggaga cgatgtcttg caagatgcca
     3241 aatatttgta cgagcaagag aaaaaagaag agcaattaga tagccttata ggtgaataat
     3301 atgtctttta aagtgctaca tagaggatac caacatatcc gactatcatc ttctttttca
     3361 cttaccttgg atattcaaga ctatcttcgt tccttggcga gagatgaaaa ggggattgag
     3421 tctatccagt tttacatgga tcaacagcac tttactctac gcataaaaga aggcttttct
     3481 gtattagata atgcagaagc ctttttaaaa agaattgata aagggaaagt ttctgagttg
     3541 atgactcttc ccattcgtag agaagagagt gcttattcta ttgtttcagg tgcagcggtt
     3601 aagcgtgtac tttttcgtag ttttgtgccg tatcctattc gctatatatg gacttgttat
     3661 caggctttgg gttatattag agaagcctat caaacactag cgcgtaagga actaacgatg
     3721 gaagtcttgg actgttcggc tattttattg tctttgttta tgaaccaatc caagacagct
     3781 agcaatatca tgtttatgct tgatttgggg aatcatttag atcagtggtc cttgaaaaaa
     3841 actgcaacag atttagaaca gagtcttctt gcaaaagaga gcgatgtatt cctagtacag
     3901 ggcgatacgg ttgttagtat caagagttcc gatgttcaaa taggagatgt cttgatctta
     3961 tctcaaggaa atgaaattct gtttgatgga caagtagttt caggtttagg tatggtcaac
     4021 gaaagttcct tgacaggaga gagttttcca gttgaaaaaa gagagtctga tttggtttgt
     4081 gcaaatacag tattagaaac tggagagtta cgcatttgtg taacagataa tcagatgaac
     4141 agccgtcttt tacagctgat tgagttgatg aagaaatctg aagaaaacaa gaaaacgaaa
     4201 caacgctatt tcatcaagat ggcggataaa gtcgtcaaat ataatttctt gggggctggg
     4261 ctgacttacc tattgacagg ttctttttct aaggctattt ctttcctatt ggtcgatttc
     4321 tcctgcgctt tgaaaatctc tactcctgta gcttatttga cagttatcaa ggaagggttg
     4381 aaccgtgaaa tggtgattaa ggatggagat gttctggaga aatatctgga agttgatact
     4441 ttcttgtttg ataagacagg aacaatcaca actagttatc ctatagttga aaaggtgtta
     4501 ccttttggag actatagtga ggaagatatt ctcagaatca gtgcctgtct tgaggaacac
     4561 atttatcatc ctattgctaa tgccatcgtc aagcaagctg agatagaggg aattgaacat
     4621 gaggaaatgc atgggaaact ccaatatatc gcaagcaagg ggatcaaatc tcatatagat
     4681 ggccaaccag ttcttattgg gaattatgtc ttgatgcagg atgagcagat tcatatcagt
     4741 tcagaacaaa atgctttaat tgaagagtac aagagtcact acaatctctt attcttggct
     4801 tatcaaaatg aattgattgg aatgttctgc attcatactc ctttgagaaa agaagcaaaa
     4861 acagccttgg ataaacttaa ggcacagggg aaaaaattga ttctggcaac aggagacacc
     4921 ttgactagga cagaggaatt agtcaaagat ttgccctttg atcaggtcta tacagacttg
     4981 aaacctgatg ggaaatttga gttagtagag aaactgcaga aagcaggtca cactattttg
     5041 atggttggag atggattgaa tgactcagcg gctttaactc tatcagatat cggtgtggtg
     5101 atgaatgaga gtgcagatat ttctaagcag atgagtgata tcttattgtt agataatcgt
     5161 ttggatttct tccaagagtt ggattcgtta tcatcatctt tgcaaacact catcaagaaa
     5221 aatattcaag ataccgttgt cgtaaatagt agtttgattg gcttcggctt atttaattgg
     5281 ctcagtcctt caaatctctc tatcttacat aatctaacaa ccttgcgcat tgtcctgcgt
     5341 agcctgtcta ttaaaaatag atagatgaga gttattaaca gcaaaaagga gttacctttc
     5401 tcgaggctaa ctcctttgtt tatagataaa tgttgaatag tttagtaagt caatacaaag
     5461 tattttttct tcccacgacg gataacagtc agttcattct ctaacttatc agcgtcactc
     5521 aagacatagt caagctcttg gatgcggtcg ccgtttacgt agatggctcc gttttggacg
     5581 tcttcacggg cttggcgttt tgagttaact ataccagatg agacgagcag ttccacgata
     5641 ttgttgtttt cgtctgcctg tacttggtag tttggcacac cacgaagtcc ttgtttgagc
     5701 tctttgacag aaaggttttt gatgtttcct gcaaagagtt gctcagtgat gttaagtgct
     5761 tctttgtagg cttcttctcc gtgaacaagt gtaacaactt cacgagccaa gactttttga
     5821 gccaagcgtt cgtgtggcgc tgcttcaaat tgtttacgaa tatcttcaat ctcatcaagt
     5881 gacaagaaag taaagatttt caagaagcga acagcgtcag cgtccatcac gttcatccag
     5941 aattggtaca tttcgtatgg agaagtcttt tcgggattga gccagacggc atttccttct
     6001 gatttaccaa atttcttacc agttgcatct gtgattagtg gaacagtgat aacgtgacca
     6061 gtcttgtccg ctttacgacg aagcaattcg gtaccagctg tcatatttcc ccactggtca
     6121 gaaccaccga tttgaagagt gacattatgg tcttggttaa ggacgaagaa gtcgtaccct
     6181 tgcatgattt ggtaagcgaa ctcagtgtaa gaaattcctg tttcgattcg tttttttaca
     6241 gattccttac tcatcatgta gttgaccgtg aagtattttc caatatcacg gaggaagtca
     6301 atgaagctga tgctgccaaa ccagtcgtag ttgttgacca tgacagcctt gttttcgcca
     6361 ttttcaaagt caagaaaacg agaaagttgt ccttggatag acttgaccca gccatctact
     6421 gtgtcttttg tttggagact acgttcagca tctttgaagg acggatctcc gatgagacct
     6481 gtagcaccgc caacgagcgc ataaggtttg tgacctgcta gttgcaagcg acgacttgtc
     6541 aagattgcga caaggtggcc taggtgaagg ctgtcagcag ttggatcgta gccagtataa
     6601 taagaaactt gaccttcttc tagggcttta cgcaaagctt cttcatcagt cgtttgaaat
     6661 atcaaaccac gatcttttag ctcatcaaaa atgtgcatgt gtcttttctc ctttttaaaa
     6721 ttattgtttc tacctattgt atcacaaact tgggcaatag cctagcagaa tagggaagaa
     6781 agtggctatt ttattgaaaa tttccctttt gtggtataat agatagagtg aggaaatcca
     6841 tgcaaaatca attaaatgaa ttaaaacgaa aaatgctgga atttttccag caaaaacaaa
     6901 aaaataaaaa atcagctaga cctggcaaga aaggttcaag taccaaaaaa tctaaaacct
     6961 tagataagtc agccattttc ccagctattt tactgagtat aaaagcctta tttaacttac
     7021 tctttgtact cggttttcta ggaggaatgt tgggagctgg gattgctttg gggtacggag
     7081 tggccttatt tgacaaggtt cgggtgcctc agacagaaga attggtgaat caggtcaagg
     7141 acatctcttc tatttcagag attacctatt cggacgggac ggtgattgct tccatagaga
     7201 gtgatttgtt gcgcacttct atctcatctg agcaaatttc ggaaaatctg aagaaggcta
     7261 tcattgcgac agaagatgaa cactttaaag aacataaggg tgtagtaccc aaggcggtga
     7321 ttcgtgcgac cttggggaaa tttgtaggtt tgggttcctc tagtgggggt tcaaccttga
     7381 cccagcaact aattaaacag caggtggttg gggatgcgcc gaccttggct cgtaaggcgg
     7441 cagagattgt ggatgctctt gccttggaac gcgccatgaa taaagatgag attttaacga
     7501 cctatctcaa tgtggctccc tttggccgaa ataataaggg acagaatatt gcaggggctc
     7561 ggcaagcagc tgagggaatt ttcggtgtag atgccagtca gttgactgtt cctcaagcag
     7621 catttttagc aggacttcca cagagtccca ttacttactc tccttatgaa aatactgggg
     7681 agttgaagag tgatgaagac ctagaaattg gcttaagacg ggctaaggca gttctttaca
     7741 gtatgtatcg tacaggtgca ttaagcaaag acgagtattc tcagtacaag gattatgacc
     7801 ttaaacagga ctttttacca tcgggcacgg ttacaggaat ttcacgagac tatttatact
     7861 ttacaacttt ggcagaagct caagaacgta tgtatgacta tctagctcag agagacaatg
     7921 tctccgctaa ggagttgaaa aatgaggcaa ctcagaagtt ttatcgagat ttggcagcca
     7981 aggaaattga aaatggtggt tataagatta ctactaccat agatcagaaa attcattctg
     8041 ccatgcaaag tgcggttgct gattatggct atcttttaga cgatggaaca ggtcgtgtag
     8101 aagtagggaa tgtcttgatg gacaaccaaa caggtgctat tctaggcttt gtaggtggtc
     8161 gtaattatca agaaaatcaa aataatcatg cctttgatac caaacgttcg ccagcttcta
     8221 ctaccaagcc cttgctggcc tacggtattg ctattgacca gggcttgatg ggaagtgaaa
     8281 cgattctatc taactatcca acaaactttg ctaatggcaa tccgattatg tatgctaata
     8341 gcaagggaac aggaatgatg accttgggag aagctctgaa ctattcatgg aatatccctg
     8401 cttactggac ctatcgtatg ctccgtgaaa agggtgttga tgtcaagggt tatatggaaa
     8461 agatgggtta cgagattcct gagtacggta ttgagagctt gccaatgggt ggtggtattg
     8521 aagtcacagt tgcccagcat accaatggct atcagacctt agctaataat ggagtttatt
     8581 atcagaagca tgtgatttca aagattgaag cagcagatgg tagagtggtg tatgagtatc
     8641 aggataaacc ggttcaagtc tattcaaaag ctactgcgac gattatgcag ggattgctac
     8701 gagaagttct atcctctcgt gtgacaacaa ccttcaagtc taacctgact tctttaaatc
     8761 ctactctggc taatgcagat tggattggga agactggtac aaccaaccaa gacgaaaata
     8821 tgtggctcat gctttcgaca cctagattaa ccctaggtgg ctggattggg catgatgata
     8881 atcattcatt gtcacgtaga gcaggttatt ctaataactc taattacatg gctcatctag
     8941 taaatgcgat tcagcaagct tccccaagca tttgggggaa cgagcgcttt gctttagatc
     9001 ctagtgtagt gaaatcggaa gtcttgaaat caacaggtca aaaaccaggg aaggtttctg
     9061 ttgaaggaaa agaagtagag gtcacaggtt cgactgttac cagctattgg gctaataagt
     9121 caggagcgcc agcgacaagt tatcgctttg ctattggtgg aagtgatgcg gattatcaga
     9181 atgcttggtc tagtattgtg gggagtctac caactccatc cagctccagc agttcaagta
     9241 gtagttctag cgatagcagt aactcaagta ctacacgacc ttcttcaagg gcgagacgat
     9301 aattctctaa atgaagtggc caatcaatgg attgccactt ttttcctttc gtgttacaat
     9361 aagggtatga atcagtatca gaaaaagatt gttaacggaa aaatttattc gctcctatcc
     9421 ggcttaatat ggggaatctg tggaatttta ggagagtact tctttactca ttatcaggtg
     9481 tcttcgggct ggattacctc tatgcgtttg acactggcag ggagtcttgt actcatttgg
     9541 tctgcaatac aattaaaatc gcaagtgcta gatatttggc gagacaagaa aaattacctg
     9601 ccctttttag cctatgctat tttggggatt ttttcagttc agtatttttt ctatctctgt
     9661 gtagaatact caaatgctac gacagcaact attttacagt ttattagccc tgtctttatc
     9721 ctcttttata atcgcttggt ttatcaaaaa cgagcgtcaa aaagcgctgt tttctatgtt
     9781 ttggttgcca tgctgggtgt ttgcttgatg gcgacaaagg gagatctctc tcagttatcc
     9841 atgacgccgc tagctcttat aacaggtttg ctgagtgcca tgggtgttat gtttaatgtt
     9901 atcttgcccc aaccttttgc taagcgttat ggttttgttc ctacggttgg gtgggggatg
     9961 attttggcag gtttgtttag caatgtcctc tcgccggttt atcagctttc ctttactctt
    10021 gatatttgga gtatcttgat ttgcctcatt atcgctttct ttggaacggc ttttgctttt
    10081 ttcatttcca tgaaggctgt gtccttggtt tctcctttgg tggtttccgt tatcagtgcc
    10141 agtgaacctc tctcttctgc tctcttgagt gttttgttct taggattagt agtggattgg
    10201 tccctccttc tagctatagc cttgattatt ttacccatga tatttttgtc tatagaagaa
    10261 gcgaaagaaa gtagataaaa agtcttttct taattctaaa agtgtgctat actagaatag
    10321 tcaataaaac acggggagat agttgtgaag agtgttttta ggttgtatcg gtaggggctt
    10381 gcttttaccg acagcacgtt ttatctcaca accctaaaaa atcataccta aaaacagaca
    10441 aaaaggtttc aaatttgagg ccttttttgg tagaataggt atcattataa cgaaccagga
    10501 ggcacctatg actgctacaa aaatgaacgc tcaagaaatt atccaattta tcgccaatgc
    10561 tgaaaagaaa accagtgtca aagtaacctt tgaggggcaa ctcgcaactg ctgtgcctag
    10621 ctctgttgtc aaactaggaa atgtcctatt cggagactgg aaggacgtgg ctccgcttct
    10681 tgaaggtttg gtagaaaatc aagattatgt tgtcgagcaa gatgctcgta attctgcagt
    10741 tcctttgcta gataagcgtg ctatcaacgc tcgtatcgag ccaggtgcta ttatccgtga
    10801 ccaggtggaa attggtgaca atgctgttat catgatggga gctgttatca atatcggtgc
    10861 tgaaatcggt gctggaacca tgattgacat gggtgccatc cttggtggcc gtgccatcgt
    10921 tggaaaaaat agccacgttg gtgcaggtgc agttttggca ggtgtgattg agccagctag
    10981 tgctgaacca gtccgtgtcg gagacaatgt tcttatcggt gctaatgcag tggttatcga
    11041 aggagtccaa atcggtagtg gttcagttgt cgcagcagga gctattgtta cccaagatgt
    11101 cccagaaaac gtggtagtag caggtgttcc agctcgtatt atcaaagaaa ttgatgccca
    11161 aactcaacaa aaaacagcgc tagaggatgc gcttcgtacc ttgtaattgt aaaagtaaaa
    11221 aagaggcgga accctttttc cagcctcttt ctgctatatc ggaggacaga tagatgttag
    11281 atttgattca gactagacga gatttacacc agataccaga gattggcttg gaggagttca
    11341 agactcaggc ttatttgctg gatgtgattg agaaattgac tacgggcaag gattttgttc
    11401 aaattcgtac ttggcggaca gggattttgg tctacctgca gggaagtcag ccggagcgaa
    11461 ccattggttg gcggacagat attgatggcc tgcctatcgt cgaacaaaca ggtctacctt
    11521 ttgcttctca acaccaaggt cgcatgcatg cctgtggtca tgattttcat atgaccattg
    11581 ccttaggctg tcttgagcgc gcccttgagg agcaacccaa gaataatctg ctctttctat
    11641 ttcagcctgc tgaagaaaat gaagctggtg gtatgctcat gtatgaggac ggtgcttttg
    11701 gagattggtt gccaaaccaa ttctatggtc tccatgttcg tccagatttg aaagtcggcc
    11761 agattgcgac taatactcat acactctttg caggaacttg cgaggtgaag atccgtttca
    11821 aaggcaaagg tggccacgca gcttttcctc atgaagccaa tgacgccttg gtggcggcta
    11881 gttactttgt gacccaagtg cagtcagttg ttagccgcaa tgtcaaccca atcgagggag
    11941 cagtggtgac cttcggcgtt tttcaagctg gaaccaccaa caatgtcatc acagacacag
    12001 cttttttaca tggaactatt cgtgccttga cacaggacat gagtctcttg gtgcaaaaga
    12061 gggtaaaaac agttgcagaa ggggttgcag ctgcctttga tatggaagtc gaagtggaac
    12121 tcaaacaagg tggataccta cctgttgaga acaatccagc cttggcgcgt gaactgatgg
    12181 acttctttga cgaaaaagac ggaatcgagt tgattgatat cgaacctgct atgacaggcg
    12241 aggactttgg ttatctcctt tcaaaggttg atggcgtgat gttttggcta ggtatcgata
    12301 gtccctacgc tcttcatcac cctcaaatga gtcctaagga agaagtctta gctattgggg
    12361 ttgatgcagt ctctagtttc ctgaaaaaga aggcagcaga atagagggct tgtatatgaa
    12421 atcggaatta cgcaagcaag tcttgcatga aatgaaggct ttatctcaag aacaaaaaca
    12481 ggctatagac caagctttaa ccgagcgaat tttacaacac cccttttatc aagaagccaa
    12541 ggtcatcgca acctacctct ctttttctca tgagtttcaa acgcgggaac tgattgagca
    12601 ggcgctgaag gacggcaaga aggttttaat acccaaaact tatcccaagg ggcgcatgga
    12661 ctttgtagtc tatgatccgc agcagttggt aaaaactgcc tttgccttac tggagccaca
    12721 gggagatttg gaagtggtgg atgtatctca gattgatttg attcatgttc ctggcctggc
    12781 ttttacgacg gatggatatc ggattggata tggtggaggt tattatgacc gctatctgga
    12841 acatttttct ggtcatactt tgagtacggt tcatccttgt caaattcagg actttatacc
    12901 tgaaaaccat gatattcctg ttcaggaggt attaattgat gaaggaaatc tttgatagac
    12961 gttaccctgt gacgagtttc ttcctcttag tgacggcctt ggtattttta ctaatgttgg
    13021 tcactgcagg cggaaacttt gacagggcag atacattatt tcgatttgga gccatgtatg
    13081 ggccagctat tcgcctcttt cccgagcagg tttggcgtct cttgtctgcc atttttgttc
    13141 atattgggtg ggaacatttc attgttaata tgctttcact ttattatctt ggaaggcagg
    13201 tagaggagat tttcggctct aagcagttct tttttctcta tctcttatca ggaatgatgg
    13261 gcaatctctt tgtttttgta tttagtccta aatccttagc agcaggcgcc tctacctctc
    13321 tttatgggct atttgccgcg attatcattc ttcgctatgc aactcgcaat ccttatatcc
    13381 aacagctagg gcaatcctat ctgacacttt ttgtggttaa cattattgga agtgttctga
    13441 ttccaggaat cagcctagca ggccatatcg gtggtgcagt tggtggcgca tttctagcag
    13501 ttatctttcc agttagagga gaaaaacgga tgtataacac cagccagaga ttaggagcgg
    13561 tagtcttgtt cgtaggactc gccattttgc ttttctacaa gggaatggga atgtgacgaa
    13621 gttgaaagaa aatttgtgta atgaaaaaag ataaggcatt ttttgaacct tatcttttta
    13681 ttttattcct tctcagtcaa ttcttttcca agttggatga ggtaattctt caaatcatct
    13741 ttgacttgtg gatgtttgag ggcgtagtca atagatgttt tcataaagcc aaacttatcc
    13801 ccaacgtcgt aacgagctcc tgtaaattca cgggcaaaaa cacgctgtgt tttattaaga
    13861 gtatcgattg catcagtaag ttggatttca tttccagcac caggagcttg gttttcgagg
    13921 atttggaaaa tttcaggcgt gaggaggtag cgtccgataa tagcaaggtc gctaggagcg
    13981 tcctctggag ctggtttttc aacaaaggtt tcaacactgt aaagaccatc ttttccttcg
    14041 ccttgcggag caataacccc gtaagcagat acttcgtcat gagggactgg catgacagcg
    14101 atagtagacg cgtgggtacg cttgtagtca tccatgagtt gtttggtaag tggaacagcc
    14161 ttttcgtctg tgatatccat caagtcatca ccaagcataa cgacaaaagg ttcatttccg
    14221 acgaaagcct tggcttgcaa aacagcatct ccgagaccgc gtggatgagt ttggcggata
    14281 aaatgcagac gcatgccagt tgtttcatca actagcttca aaagatctgt tttccctttt
    14341 tctttgaggt tatattccaa ttcgaagttt gaatcgaagt ggtcctcaat agaacgtttt
    14401 gatttaccag tgacaactag aatatcttca atacctgatt tgagagcctc ttccacgata
    14461 aactggatag ttggtttgtc tacgattggc aacatttctt tggcaagggc cttggttgct
    14521 ggtaaaaatc gagttcctag tccagcagca gggataactg cctttctaac ttttgatgtc
    14581 ataaaaatcc tttctataga gggttaagac cactcatttt ctgctttaaa ttcattgttc
    14641 atgatgtcat aaatggcatc tttgatattg gttccgtgat aaataacttg gtaaatagcc
    14701 tgtgtaatgg gcatatagac tccaagttct tgggctagtt cataggctgc tcgagtcgtt
    14761 gaaattcctt cgattaccat gcccatatta gcttctatat cagctaggga ttctcctcgt
    14821 ccgagagcat ctccagctct ccagttacga gagtggatgg aagttcccgt tacgatcaaa
    14881 tctcccacac cagataagcc gctataggtc aatggactgg ccccgagtgc tacccctagg
    14941 cgggtgattt ctgctaaacc tcgagcgatg atggctgcct tagcattatc accaaatcca
    15001 agaccatgta aagctccagc accgacagca ataatatttt taagagcacc agcagtttca
    15061 accccgataa catccgtatt ggtataaagt cggaagtagt gattactaaa tagcttctga
    15121 acgtattgag ctgtttgtaa atctttagaa gcagcagtta ttaaagttag gtcacgcaca
    15181 atggtctctt ctgcatgact aggccctgaa acaacgacga tatcactacg gagatgttca
    15241 ggaatttctt cttcaagaat ggttgataat cgtttatggc tatcaggttc taatcccttt
    15301 gatgcgtgca tgatgataac cttatggtcc aaggtttgtg caacttgctg ggcaacaagt
    15361 cgtgtcactt ttgttgggac aacaaacaaa atcgcatcca catctttcaa tgtttctgct
    15421 aagtcggtgt aggcaatgat attttcgtct agaacgacat ctttaaagta gtgcttatta
    15481 gtatggtgtg tattaatttc attgatttgc tcgggaagat ttccccaaat acgtacctcg
    15541 tgtccattgt catttaagac ttgtgaaagg gcggttcccc aagaaccagg ccccaagacg
    15601 gcgacggttt gtttttccat gatttcctcc ttgatagagt tctttctctt attctatcat
    15661 attctagagg attttgcact tgcattactg gggtatggtg gaaaaataca caaaaaccga
    15721 gacgaaggga taaactctta gtctttagtt aaagtgagaa gaaatctgat agatagtttg
    15781 attcagtata tgcttataat agaggtaaac aactcaggag gttcttgtag gttgcgagag
    15841 tttggcgaaa aaattaaaag attacgtttg gctaaaaaaa tcagtcgttc agaattttgt
    15901 ggtgatgagt ctgaattaag tatccgtcaa ttaattagaa ttgaaaatgg agaatccaga
    15961 ccaatactaa caaagttaaa atatattgct gaacgtttgg gggttgaaga ttacaagttg
    16021 atgccaagtt atatagagtt ggataaggaa tacctagaat tgaagtattt cttgatgagg
    16081 attcctacat acgaagatga aactatcgcc caaaagaaag agagtgtttt gataagattt
    16141 ttgaagagta ttatgatagg ttacctgagg aagaaagatt tatcatccca aattattcat
    16201 atctggcact aacgaactac acagttcaaa aattaccaga aaagctagtt gaaatactgt
    16261 ccttctggtg attttgctta atttctgatg ttcgagacat aattgaggag atttgtcttg
    16321 attttttcct aaaaaagggc agactcctcc cttggtttga tgctcgattt ttaaaataag
    16381 gtgacttatt ctgttaggca tgttttcccc tgccctctag ctctatatgg aacagggagt
    16441 atcagattta tctggcagat tgtatcaaat aaggcttgaa actgttttga ataggcgtat
    16501 agacttgaga atttgagaat atgtcgtcta gcagtagaga catattttcc ggcaatatga
    16561 aggaagagac gtcgaaaacg cttgatagtc aaggccttta cttcatcacc agctagctgc
    16621 tttaaaaaga ggtagagatt ataagccaga cagcccatca tcatacgtac ttcattctta
    16681 atcatggtcg aactatctgt cttatcccca aagaatcctg ctttcctttc tttgataaag
    16741 ttttcagcat tccctcgttc acgatagaat tgaaacagct cctcactatc tacactgctt
    16801 aaattgttca aatgaacttt tttacaacca taaaaaagag cacttaatcg tactcttctc
    16861 ttttaaggat tagttgaatt aattcaaatc caccagttct cctgtttcta ggtagactag
    16921 gcgttcacaa atgttagcaa tgtaatcagc gaagcgttcc agatgcccta tgatataaag
    16981 gtattgagtt ccattgggaa ttgaggtttc ttggtctttc ataagtccaa tgatttcctt
    17041 tgataaggca taataatatt ggtcaatctg ttcatctttt tgagcaatac taatagcttt
    17101 tgaggcttgg tgcaaaggaa aggcaaccaa taaatcggct agcatgctga gggataattt
    17161 acccatttgg tgtaactgtt cttcgtcagg ggctagttga ttttctttta gttgcaaaac
    17221 agctttggca atgcctgcca tatggtctcc catacgttca aggtctgaac aagaagacat
    17281 gatgctaatt acaaatcgaa ggtcagacac ttgtggctgc tgcaaggcta acaaacgggc
    17341 acaggccaat tcgatagcgc tttgaccttg gttgatagca tgatccttat tgataattag
    17401 ctctgccatc tccttgtctt tggaggctaa ggccagtaag gcttttgaag ctgtttcaag
    17461 gacaagttgc cctagtccta aaaaggattg ttctaattca tgcaattcta agtcaaattg
    17521 atttctcata ggtttttcct tccttatccg aaccgtcctg aaatatagtc ttctgtgcgc
    17581 tgatcttttg gattggtaaa cacgtcaacg gtatctccaa attcgcaaat ttctcctgtt
    17641 aagaaaaaag cagttttatc tgaaatacgt gaagcttgtt gcatgttatg ggtaacaatg
    17701 ataatcgtat aatccttttt tagttgctga atgaggtctt caatttttaa agtggagata
    17761 gggtctaagg ctgaagtcgg ctcatccatt aacagaatat caggttctac tgctaaagct
    17821 cgcgcaatgc aaaggcgttg ctgctgaccg ccagataagg acatggcact ctttttaaga
    17881 tcatctttga cttcttccca aatggctgcc ccttttaaag atttctccac taaggcatct
    17941 aattgttttt tgtctcgaat accatgtgtc cttgggccat aagccacgtt atcatagata
    18001 gacatggcaa agggattagg ctgttgaaaa accatcccta cacgcttacg tagctgatta
    18061 aggttgaatt tgctactata aatatcttgc tcatctaaga ggacttggcc ttcaatatgg
    18121 caagaaggaa ccaaatcgtt catccgatta agggttttta gaaaagttga tttaccacaa
    18181 ccagatgggc ctatcaaggc agtaatctgt ctttctggta attgaatcga aatatttttt
    18241 aaggcttgaa aatccccgta aaataagtct aggtgtctga ctgaaaatgt tcccatacta
    18301 ggaagctcct ttcacaagtt tccgagataa taagcttgat agagtattta tcattaaaac
    18361 agtaataatc aaaatcacac cggtagcata ggcttcattg acatgtagcc cctcacttga
    18421 cagcatatac atatgcaggg ctagagaacg acctgaagac atgagactac ttggcgtatt
    18481 ggtagaggta cctaatgtat acatgagggc agctgtttca ccaacgatac ggccaatagc
    18541 tagtatcact ccagctaaaa tacctggcat ggcaactggt agaacaattc taaaaacagt
    18601 ccgtaactta cctgccccaa gtccataact tgcttgacgc atgctatcac taacagataa
    18661 aagggcttct tctgttgagc gaataatgac tggcaacacc atgataactg aggttaagat
    18721 tcctgataac agagagtatt gaaaacctaa gaagactaca aagaagagca tgccaaacag
    18781 accaaaaaca atggaaggaa tcccagataa ggtatctgag gccaatcgca tgattttaac
    18841 acaaagggaa tctttttttg tatattccac aagataaaaa ccagcaaaaa tccctatggg
    18901 caaggctaaa agaagagcac caaagaccag aataacggtg gaaataatcg ctggcataag
    18961 ggaaatgttc tcagaagtat aagtccaaga aaagagggat agacttagat gaggtaagcc
    19021 tttgatgagg ataaaaccaa tgactaaaaa gagagagcca aaggttaaag ctgaaaaaca
    19081 ataaacgaga agttttagca ggtatttact cataagatga ttttcctttc aagtaggcaa
    19141 agtaggcatt aatcaagaga ataaggaaaa agagaactgc tgaggttgca ataagggctt
    19201 ccctatgctg acctgatgcg taagccattt ccagaacaat attggttgtt aaggttctgg
    19261 ttcctgaaaa gagtccactt ggaataatcg gttggttgcc tgctaccaaa ataactgcca
    19321 tggtttcacc tactgcgcga ccgattccta aaataactgc tgataaaata ccagatctcg
    19381 cagctggcaa gatgacacta aaaatactcc gttcatgact agctcctaga gccaagctac
    19441 cagaataata cgttttggga actgttcgga tagcagattc tgacaaactg ataatggttg
    19501 gcaaaatcat tattcctaat agtaacgaag cggttaggac actcatgcca tttcctaaaa
    19561 agcttctaat ccaaggcacc aataattgta ggccgaaaaa accataaaca atagatggaa
    19621 tggccgccat caagttgata gctgatttta agaagccata gacgggcttt ggacaataat
    19681 aaaccataaa caccgatgtc aagatgcctg ttggcacccc aatcacaatc gctcctaagg
    19741 taattaataa ggaaccaacg atcattggta aaataccata gcttgccgga atgttcgttg
    19801 gcgaccaatc actgcctaat aaaaaacggg caaagccgta gttagccatg aaaggtaagc
    19861 cattactaaa aataaagaaa cagattagca aaatagctac aacagctact gttgcactca
    19921 tgaaaaaaat tgccctaaaa actgcttctt tgaaggcttg ttttatcaca tcttgtcctt
    19981 tctagtgaag aaagtaaggg agatacgaca cctccctact tgccttcttt atcttattgt
    20041 acgatgaaac gtctgcatct ctttagagat ttatggagca aacattttat ttaatcttgt
    20101 cccaggtggt taatttgcca ctaaaaacgt ctgcaagttc agccatactg acttggcttg
    20161 ccttattgtc attattgacc acaacagcaa taccgtctaa agcaatagca tcatgggtga
    20221 gactcttacc ttcttcagga gttaattccc tagaaaccat accaatatca gcggttttct
    20281 ccttaacagc ggtaatacct gctgaagacc cattagaggt aatatcaatc gtaacttctg
    20341 gattttcttt tttataagct tctgctaatt tttccattaa agaagatact gaagtggaac
    20401 ctacaacaga caacttgcct gataagtgtt ggctggtata ttctgtggtt tcggttttag
    20461 cttcaataaa tttattatct gtgaccactt gttgaccttg tttggagtgg ataaagctga
    20521 taaaatcttg acctagcttg gaaagattag aagaccaaac aatgttgaag ggacgttgaa
    20581 gagggtattt accatctaaa actgtgtctc gactagcctt gacaccatca atctctaaag
    20641 ccttgacaga tttcgttaaa gatcccaagg agatgtagcc gatagcatta gcattccctt
    20701 gaactgctga gagaacacct tctgtactat tttgaatcac agctgttttg gcagtgttgt
    20761 caattttttt atcaccgtct tttttgagaa tccctgtgat ttctgtgaag gcaccccgtg
    20821 tcccagagcc attttctcgt gaaatcacct caatcgttcc tgaagctgac tgtttggaag
    20881 cagctgactg attgccacag gcaacaagcc caaatcctga taagccaatg gctgcaagag
    20941 taagcatttt tttgaatttc ataataatca cctttatctc tatgtatttt tcttgtgtag
    21001 gcttactaca tttatagtct aacaagtctt tgtaaaggtt tatccctgat tcatgtaaag
    21061 attgtgtaaa gaatcaaaaa aagccacttt tgaaaaatgg ctgctcctaa aaatagcttt
    21121 aaaaattatt agtcctgtgc gaaagattgg ttaggaagaa aaatcgtgaa gcaactgcct
    21181 ctgccaagct gactcgtcac cgtgacttgg ccacctaata attgactgag ttctttgaca
    21241 atggcaaggc caagaccagt gccaccagtt tgtctgcttc gacctttatt aactcggtaa
    21301 aaacgttcaa aaatacgatc ctgctctaat tgactaatac caatccctgt atctgataca
    21361 gaaatcttaa tgccttcgtt caccttttgg gtcttgacct caatttttcc cccttgttca
    21421 gtgtaacgga tggcattgga taaaagattg agtaagattt gggaaagtaa ttgactatct
    21481 gatacgaggg tgacatcatc tggcacctgc acctttagct gtaaatcctt cttcttgagc
    21541 tgaggttgca agctttgagt caaatcctgt acaaattctg ccaaagaaag ggtcgtccat
    21601 tgtataggca tttgttgagc cttagataag gtaagaagat gctcaacaat atgctcaaga
    21661 cgcaagcttt ctttgtaaat aatgtctaga aagtcatcct tgagcgcttc ttcttcagct
    21721 gacatcccct taatggtttc agcaaagccc ttaatcgaag taactggtgt cctcaattca
    21781 tgggaggcat ttgagacaaa ggctaaattt aacttttcat aagttctaat cgttgttaaa
    21841 tcatatagca agacgagcac agcttccaca gattgggtgg ggctaaaaac gggaactgct
    21901 gtcacttcta aaatcaagtc accctcatga aacccactta cttcttgttt taaccttgtt
    21961 ttttgatcaa aggcttggtg aactaaattt cgaatatcca tccgtttgag gtcatcaagt
    22021 gaacttatgt cgccgtccac atcgggaaaa taatgaggca gagagcgact ggataataac
    22081 atctgacctt gagcggaaac taaaaacgtc cccatggtta ggtgcgacag aagaacctcc
    22141 attgtttcgg ctaggtcctt gtattgctga tcctgttggg agactttggt ttttagggca
    22201 gacacatact gagccaaaga ctttaagtct tcttgccctt tttctaaaaa gtattcacta
    22261 ctggtcaaga gaggttggtg caaggtctca aaagcaactt cccatttcca aaggcaaaag
    22321 agccagtagc caccttgtcc caaagaaagg gctagaagaa agagaccgat gcctttactg
    22381 atccaagtta atgccatccc tgcaatcaga atgaggctaa cacttagatt gactagccaa
    22441 aattgaaggt agcgtttcat ctataactcc ttgaacttat aaccataacc ccgaatggtt
    22501 cgaataaatt gaggggcttt aggattgtct tcaatttttt ccctcaactt accaatatga
    22561 acgtccacca aacgtgtttc ctgcccaaag tcataccccc agatacgttc caaaagacgc
    22621 tctctagtca gtgtcatgtt gggatgtttc ataagataga gcaagagttc aaattctttt
    22681 ggggtcaaac tcagtaactt attcgccttg tagacttcat gacgctcagg gtatactttc
    22741 aaggtcccaa atagccaaga atcgtcagcg atattatctg aatcatctcc ttcttgttct
    22801 cctttagttc gcctgaggac agccttgaca cgcgccagca attctctagg gctaaaaggc
    22861 ttggtcaggt agtcatcagc ccctaattcc aaggccaaaa ccttatcaaa ttcatcactt
    22921 ttcgcagaaa ccatcataat tggagttttg acgcctttgg ctctcagccg cttacaaact
    22981 tccatgccat ctaattgtgg taacatgata tcaagcaaga taaaatcaaa gggttctgtt
    23041 tctgccaaag ctaaggcctt ccgtccattt gttaccaatt gagtagaaaa gccttcctta
    23101 cttaaatggt agtcaagcaa tttcagaatg tgttcttcat catccactaa taagacttgt
    23161 tttgtcatct attatctcct attggtaaca ttataacaca attatcagaa atcctaacat
    23221 tgctaaatca gattaaattt gcttatcaag actagtatct ggtcaaacgc tcaatcatct
    23281 ccttgtgctc tggataggtc gccagtagat ctaccctttc aaataattca aaatcctcaa
    23341 attcaaaacc aggagcaaca agacaagaaa ccagagcata atccttatca actgttgatc
    23401 cccaaatagt gcccttagga acacagtagt gaagttgttg ccctttggat atgtccaggc
    23461 ctaaagtgac tgcttcgtag tgaccatctg ctgtaatcat gtgaacagta agtggggatc
    23521 ctgcatgaaa ataccagatt tcatctgctg tcaatcggtg aaaatgtgaa ggattcgttt
    23581 cttcttaata agaaataaat actggtataa agcgcccttc ccttaccagc aaggtttata
    23641 gtgtctgaag ctttttttgt ttgtctaaaa tagccacctt caacatgggg agctaactct
    23701 agagttctta tcaagtcttc tttatccgtc ggagccaatg ggttgaagta actcttgttc
    23761 aaagtggtgt tacgatttca agaactcctc tcagttctga ggacacggta atgattgatg
    23821 cgacggaagt acaaatcaat cgccctaaaa aaagaattag cgaattattc tggtaaaaag
    23881 aaatttcacg ttatgaaggc tcaagcgatt gtcacaagtc aagggagaat tgtttctttg
    23941 gatatcgctg tgaactattg tcatgatatg aagttgttca aaatgagtcg cagaaatatc
    24001 ggacaagctg gtaaaatctt ggctgacagt ggttatcaag ggctcatgaa gatatatcct
    24061 caagcacaaa ctccacgtaa atccagcaaa ctcaagccac taacagttga agataaagcc
    24121 tataaccatg cgctatccaa ggagagaagc aaggtcgaga acatctttgc caaagtaaaa
    24181 acgtttaaaa tgttttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg
    24241 aatttgattg ctggtcttat caatcatgaa ctaggattct agttttgcag gaagtctatt
    24301 atttggttag gtgaattagt gaagcgttta ggcaagtgtc tctggttacg acgtaaagaa
    24361 gcataaatcg ataatattta tgtttcttta ctagtgaaac gcctagccaa attaccatag
    24421 ttacgacgtc atggcctcta aatcgattat atttaggggt catgactagt gaagcagtta
    24481 gctagttcgc atataagcgg ctagcgtcta acaattagga actttagttc caataacttt
    24541 aagattacga cgttttagga cataaatcga tcatatttat gtcctaaaac tagtgaagcg
    24601 cctagccaaa gtccgaatag gatttggcgt tagttactta gattgctttg caatcaagta
    24661 actttggcga tttacatctt ctctggcgct tctactccaa gcaagcgaag ggcttctttg
    24721 agaacgactg cggttgcgta gctgagggct agacggctgt cgcgttctgg gctttcatcc
    24781 aagatacgtg tatgtgcata gtatttgtta aaggattgag ccaggctaat tgcaaattta
    24841 gcaatgatag aaggttcaaa gttatctgcc gcacggttga taatacgtgg gaagtcttga
    24901 atgagtttaa tgatttccca gctttcagta tcattcaagc tatagttgcc agctgtttct
    24961 ggtttgaaat cggctttacg taagatagat tggatacgag cgtaggcata ttgaacgtaa
    25021 ggtccagttt caccctcgaa ggataccata gcttctaggt cgaagtcgta tccatttgta
    25081 cggtcggttt tgaggtcata gaatttaatg gctccaaccc caacagcatg tgctacctga
    25141 tctttatttt ccaattcagg attttttgct tcaatttggg ctttggcacg gctaacagcc
    25201 tctgcaacag taggctctag caagatgaca ttccctttac gagtagagag tttcttccct
    25261 tcttttgtaa ccagaccaaa aggaacgtga gtaatgtcgt cactccagtc gtagcccatc
    25321 tcttgcaaga cagctttgag ctgtttaaag tgggcagatt gttcttgacc aacgacatag
    25381 atagatttag caaattggta ttcgttttta cggtaaaggg ctgcagccaa gtcacgtgtg
    25441 atatagagag ttgcaccatc agacttcttg atgagggcgg gatgttcaat tccatatttc
    25501 tcaaggttca caacttgggc accttctgat tcaagaagta gtcctttttc agaaagaatg
    25561 tctacaactg catccatctt atcattgtag aaggcttctc cgttatagct gtcaaattca
    25621 accttcaatt cattgtaaag gcggttaaat tccactaaac tttcatcgcg gaaccattgc
    25681 caaagagcga gagcttcctc atctccattt tcaagtttac ggaaccattc gcgcgcttct
    25741 tcatccaagc tagggtcatt ttcagcttca gcgttgatgc ggacatagag tttaaggagt
    25801 tcatcgattg gatgagcttt tacagcttct tcgtcgcccc attttttgta ggcaacaatc
    25861 aacatcccaa attgtttacc ccagtctccc aaatggttga ccttgaccgt ttgataaccg
    25921 attttttgga aaatatgtga caagctatct ccgataacag ttgaacgcag gtggccaata
    25981 gaaaatggtt tagcgatatt cggactagac atgtcgataa caacattttc ttgtttacca
    26041 atattttggt cagcatagtg ttctttttca gtggtaacag cttgcaatac ttgagcagaa
    26101 atggcagatt tatcaaggaa aaagttaacg taaggtcctg ttgcgacaac cttttcaaag
    26161 gcttggctgt tcattttttc agccagttca gtcgcaatca tttgaggtgc tttacgttcg
    26221 acttttgcaa gagaaaaagc agggaaagcg atgtctccca tttctgagtt tttaggggtt
    26281 tccagtaaat ttaaaatagc ctcttggtcc aggctatcaa tgatgctaga taattcgcta
    26341 gcaatcaatt cttttgtatt cattaagagc tcctttttgg acttttctac tattttatca
    26401 caattttaaa gaaagaagaa aaaatttttg aaatctcccg tttttttggt ataatatagc
    26461 tataaatata gttataaata tacatataag aggattttat gagaaaaaga gatcgtcatc
    26521 agttaataaa aaaaatgatt actgaggaga aattaagtac acaaaaagaa attcaagatc
    26581 ggttggaggc gcacaatgtt tgtgtgacgc agacaacctt gtctcgtgat ttgcgcgaaa
    26641 tcggcttgac caaggtcaag aaaaatgata tggtgtatta tgtactagca aatgagacag
    26701 aaaagattga tttggtggaa tttttgtctc atcatttaga aggtgttgca agagcagagt
    26761 ttaccttggt gcttcatacc aaattgggag aagcctctgt tttggcaaat attgtagatg
    26821 taaacaagga tgaatggatt ttaggaacag ttgctggtgc caatacctta ttggttattt
    26881 gtcgagatca gcacgttgcc aaactcatgg aagatcgttt gctagatttg atgaaagata
    26941 agtaaggtct tgggagttgc tctcaagact tatttttgaa aaggagagac agaaaatggc
    27001 gatagaaaag ctatcacccg gcatgcaaca gtatgtggat attaaaaagc aatatccaga
    27061 tgcttttttg ctctttcgta tgggtgattt ttatgaatta ttttatgagg atgcggtcaa
    27121 tgctgcgcag attctggaaa tttccttaac gagtcgcaac aagaatgccg acaatccgat
    27181 ccctatggcg ggtgttccct atcattctgc ccaacagtat atcgatgtct tgattgagca
    27241 gggttataag gtggctatcg cagagcagat ggaagatcct aaacaagcag ttggggttgt
    27301 taaacgagag gttgttcagg tcattacgcc agggacagtg gtcgatagca gtaagccgga
    27361 cagtcagaat aattttttgg ttgccataga ccgcgaaggc aatcaatttg gcctagctta
    27421 tatggatttg gtgacgggtg acttttatgt gacaggtctt ttggatttca cgctggtttg
    27481 tggggaaatc cgtaacctca aggctcgaga agtggtgttg ggttatgact tgtctgagga
    27541 agaagaacaa atcctcagct gccagatgaa tctggtactc tcttatgaaa aagaaagctt
    27601 tgaagacctt catttattgg atttgcgatt ggcaacggtg gagcaaacgg catctagtaa
    27661 gctgctccag tatgttcatc ggactcagat gagggaattg aaccacctca aacctgttat
    27721 ccgatacgaa attaaggatt tcttgcagat ggattatgcg accaaggcta gtctggattt
    27781 ggttgagaat gctcgctcag gtaagaaaca aggcagtctt ttctggcttt tggatgaaac
    27841 caaaacggct atggggatgc gtctcttgcg ttcttggatt catcgcccct tgattgataa
    27901 ggaacgaatc gtccaacgtc aagaagtagt gcaggtcttt ctcgaccatt tctttgagcg
    27961 tagtgacttg acagacagtc tcaagggtgt ttatgacatt gagcgcttgg ctagtcgtgt
    28021 ttcttttggc aaaaccaatc caaaggatct cttgcagttg gcgactacct tgtctagtgt
    28081 gccacggatt cgtgagattt tagaagggat ggagcaacct gctctagcct atctcatcgc
    28141 acaactggat gcaatccctg agttggagag tttgattagc gcagcgattg ctcctgaagc
    28201 tcctcatgtg attacagatg ggggaattat ccggactgga tttgatgaga ctttagacaa
    28261 gtatcgttgc gttctcagag aagggactag ctggattgct gagattgagg ctaaggagcg
    28321 agaaaactct ggtatcagca cgctcaagat tgactacaat aaaaaggatg gctactattt
    28381 tcatgtgacc aattcgcaac tgggaaatgt gccagcccac tttttccgca aggcgacgct
    28441 gaaaaactca gaacgctttg gaaccgaaga attagcccgt atcgagggag atatgcttga
    28501 ggcgcgtgag gagtcagcca acctcgaata cgaaatattt atgcgcattc gtgaagaggt
    28561 cggcaagtac atccagcgtt tacaatctct agcccaagga attgcgacgg ttgatgtctt
    28621 acagagtctg gcggttgtgg ctgaaaccca gcatttgatt cgacctgagt ttggtgacga
    28681 ttcacaaatt gatatccaga aagggcgcca tgctgtcgtt gaaaaggtta tgggggctca
    28741 gacctatatt ccaaatacga ttcagatggc agaagatacc agtattcaac tgattacagg
    28801 gccaaacatg agtgggaagt ctacctatat gcgtcagtta gccatgacgg cggttatggc
    28861 ccagctgggt tcctatgttc ctgctgaaac cgcccattta ccgatttttg atgcgatttt
    28921 tacccgtatc ggagcagcag atgacttggt ttcgggtcag tcaaccttta tggtggagat
    28981 gatggaggcc aataatgcca tttcgcatgc gaccaagaac tctctcattc tatttgatga
    29041 attgggacgt ggaactgcaa cttatgacgg gatggctctt gctcagtcca tcatcgaata
    29101 tatccatgag cacatcggag ctaagaccct ctttgcgacc cactaccatg agttgactag
    29161 tctggagtct agtttacaac acttggtcaa tgtccacgtg gcaactttgg agcaggatgg
    29221 gcaggtcacc ttccttcaca agattgaatc gggaccagct gataaatcct acggtatcca
    29281 tgttgccaag attgctggct tgccagcaga ccttttagca agggcggata agattttgac
    29341 tcagctagag aatcaaggaa cagagagtcc tcctcccatg agacaaacta gtgctgtcac
    29401 tgaacagatt tcactctttg atagggcaga agagcatcct atcctagcag aattagctaa
    29461 actggatgtg tataatatga cacctatgca ggttatgaat gtcttagtag agttaaaaca
    29521 gaaactataa aaccaagact cactagttaa tctagctgta tcaaggagac ttctttgaca
    29581 attctccact tttttgctag aataacatca cacaaacaga atgaaaagga gctgacgcat
    29641 tgtcgctccc ttttgtctat tttttaagga gaaagtatgc tgattcagaa aataaaaacc
    29701 tacaagtggc aggccctggc ttcgctcctg atgacaggct tgatggttgc tagttcactt
    29761 ctgcaaccgc gttatttgca ggaagtctta gacgccctcc ttactgggaa atatgaagct
    29821 atttatagta tcggggcttg gttgattggt gtggccgtag tcggtctagt tgctggtgga
    29881 ctcaatgttg tcctcgcagc ctatattgcc caaggagttt catccgacct tcgggaggat
    29941 gccttccgta aaattcaaac cttttcttat gctgatattg aacaatttaa tgcgggaaat
    30001 ctagtcgttc gaatgacaaa tgatatcaac cagattcaga acgttgtcat gatgaccttc
    30061 caaattcttt tcagacttcc cctcttgttc atcggttcgt ttatcctagc ggttcaaacc
    30121 ttaccttctc tgtggtgggt gattgttctc atggtagtct tgatttttgg tttgactgct
    30181 gtcatgatgg gaatgatggg gcctcgtttt gctaagtttc aaacccttct tgagcgcatc
    30241 aatgccattg ccaaggaaaa tttacgtggc gttcgtgtgg tcaagtcctt tgtccaagaa
    30301 aaagagcaat ttgctaagtt tacagaggtc tcagacgagc ttcttggtca aaacttttac
    30361 attggttatg ccttttcagt agtggaaccc tttatgatgt tggttggtta cggggcggtc
    30421 ttcctctcta tttggctggt cgcgggaatg gttcagtcgg atccgtctgt tgttggttcc
    30481 atcgcttctt ttgttaatta cctaagccag actatcttta ccattgttat ggttggattt
    30541 ttgggaaatt ctgtcagccg tgccatgatt tccatgcgtc gtattcgaga aattcttgac
    30601 gcagagccag ctatgacctt caaggatatc ccagatgaag agttggttgg aagccttagc
    30661 tttgaaaatg tgacctttac ctatccaatg gacaaggaac cgatgctgaa agatgtgagc
    30721 tttactattg aacctggtca aatggttggt gtagttggag cgactggtgc aggaaagtca
    30781 accttggctc aattgattcc acgtctcttt gatccacagg acggggccgt taaaatcggt
    30841 ggcaaggata ttcgagaagt gagtgaagga accctgcgta aaacagtttc catcgttctc
    30901 caacgtgcca ttctttttag tggaacgatt gcagataact tgagacaggg gaagggaaat
    30961 gctactctat ttgaaatgga gcgtgcagcc aatattgccc aggctagtga attcattcat
    31021 cgtatggaga aaacctttga aagtccagtt gaagaacggg gaaccaattt ctctggtgga
    31081 caaaaacaaa ggatgtcgat tgcgcgtggg attgtcagca atccacgtat tctgattttt
    31141 gacgattcga cctcagcctt ggatgccaag tcagagcgct tggtgcaaga agctttgaat
    31201 aaggacttga aggggacgac aaccattatt attgctcaaa aaattagctc ggttgtccat
    31261 gcagacaaga tcttggttct aaatcaagga cgattgattg gtcaaggcac gcatgcagac
    31321 ttggttgcca acaatgccgt ttaccgtgaa atctatgaaa cacagaaatg aaagacaaac
    31381 tataagaaaa gtcaatagtt ttatctaaac tatttcttat ttcaatttga tgatttggcg
    31441 atgattttag agcacggcaa aaagcccttg aaaaagtcca tttttcaaag gtaatcctgt
    31501 gttaatttca gaaattacat cactttttgt tcgtcaaatg gcagctcttt tttaggatat
    31561 aaaacagggt tcggataagt ttttttgcaa ggtggatgat ggttatattg taatgttttc
    31621 cttattctaa cttagtctta agataggcct taaaagtagg cgaaaagcga gcgcatgctt
    31681 tggcaacttg tatgagtacc taccgcagat gaggggaacc ccgtttgacc attcttcctg
    31741 ctaaatcaat ctgacctgac tgataaatag aagaatccag tccagcgaaa gcttgtaatt
    31801 gagcaggatt atcaaaggca tgaatatttc gaatctcggc taaaatgacc gcccctaaac
    31861 gattcccaat cccagtaacc gtcgtgatga ccgagttgaa ctcagccatc aagtcattga
    31921 cacatttttc cgctttgtca atgatcctct tgtaatgttt gatgttttca ttacacgaga
    31981 taaaacgttt atgcgttatc aaactcatta ccaattgaaa caaaagctgt ggttagagcc
    32041 tttcggaaat tgtcaagcga ttggaggaaa tgaactaatc cacagcggct tattccaagt
    32101 ataccacttg ggctttggca gtagctaact gcgctaaata taatataagg aggagtaaaa
    32161 tgaagacagt tcaatttttt tggaattatt ttaaggtcta caagttctca tttgtagttg
    32221 tcatcttgat gattgttctg gcgacttttg cccaagccct ctttccagtc ttctctggac
    32281 aagcggtgac gcagctagcc aatttagttc aagcttatca aaatggcaat ccagaacttg
    32341 tatggcaaag cctatcagga atcatggtca atcttggtct gctggttttg gttctattta
    32401 tttctagtgt aatatacatg tgtctcatga cgcgcgtgat tgcagaatcg accaacgaga
    32461 tgcgcaaagg cctctttggt aagcttgctc agttgacggt ttctttcttt gaccgtcgac
    32521 aagatggcga tatcctgtct cattttacca gtgatttgga taatatcctc caagccttta
    32581 acgaaagctt gattcaggtc atgagcaatg ttgttttata cattggtctg attcttgtca
    32641 tgttttcgag aaatgtgacg ctggctctca tcaccattgc cagcacccca ttggctttct
    32701 ttatgctgat tttcatcgtg aaaatggcac gcaaatccac caacctccag cagaaagagg
    32761 tagggaagct caacgcctat atggatgaga gcatctcagg ccaaaaagcc gtgattgtgc
    32821 aaggaattca agaggatatg atggcaggat ttcttgaaca aaatgagcgc gtgcgcaagg
    32881 caacctttaa aggaagaatg ttctcaggaa ttcttttccc tgttatgaat gggatgagcc
    32941 tggttaatac agccatcgtc atctttgctg gttcggctgt gcttttgaat gataagtcta
    33001 ttgaaacaag tacagcccta ggtttgattg ttatgtttgc acaattttca cagcagtact
    33061 accagcctat tatccaagtt gcagcgagtt ggggaagcct tcagttggcc tttactggag
    33121 ctgaacgaat tcaggaaatg tttgatgcag aggaggaaat ccgacctgaa aaggctccaa
    33181 ccttcactaa gttgcaagaa agtgttgaaa tcagtcatat cgatttttca tacttgcctg
    33241 ataaacctat tttgaaagat gtcagcattt ctgcccctaa aggccagatg acagcagttg
    33301 ttgggccgac aggttcagga aaaacgacta ttatgaacct catcaatcgc ttttatgatg
    33361 ttgatgctgg tggtatttat tttgatggta aagacattcg tggctatgac ttagatagtc
    33421 ttagaagcaa ggtgggaatt gtattgcaag attcggtctt gtttagcgga acgattcgag
    33481 acaatatccg atttggtgtg ccagatgcta gtcaggaaat ggttgaggta gcagcaaaag
    33541 caacccacat tcacgactat atcgaaagtt tgcctgataa gtacgatact cttattgatg
    33601 atgaccagag catcttttca acagggcaga agcaattgat ttcaatcgct cgaaccctga
    33661 tgacagatcc agaagttctc attctcgatg aagcaacttc aaacgtagat acggtgacag
    33721 aaagcaagat tcagcatgcc atggaggtgg ttgtagcagg tagaactagt ttcgtcattg
    33781 cccaccgctt gaaaaccatt ctcaatgcag atcagattat tgtccttaaa gatggagaag
    33841 tcattgaacg tggtaaccac catgaacttt tgaagctagg tggcttttat tcagaactct
    33901 atcacaatca atttgttttc gaataagaaa gaagttgtcc tatgtgggca gctttttctt
    33961 gtccataaaa aatgtttatc acagccttaa aaaaaacata ttagacgaaa gtcattttga
    34021 gtgatatgat aggactatcg ttagcattcg aaaggagagg catcatggct agaacggttg
    34081 taggagttgc tgcaaatcta tgtcccgtag acgcagaagg caaaatcatt cattcatctg
    34141 tatcttgtag attcgcagag atcattcgtc aagtcggtgg tctcccttta gtcattcctg
    34201 ttggtgatga gtcagttgta cgtgattatg tggaaatgat tgacaagctc attttgacag
    34261 gaggccaaaa tgttcatcct cagttctatg gagagaaaaa gaccgtcgag agcgatgatt
    34321 acaatctggt ccgtgacgaa tttgaattgg cactcttgaa ggaagcgctt cgtcagaata
    34381 aaccaattat ggcaatctgt cgcggtgtcc aacttgtcaa tgttgccttt ggtggaaccc
    34441 tcaatcaaga aatcgaaggt cactggcaag gactaccttt agggacatct cactctattg
    34501 agacagtaga aggaagcgtg gtggctaagc tatttgggaa agaaagtcag gtcaactcag
    34561 tccatcgtca aagcattaaa gatttggcac ctaatttccg tgtaactgct attgattcaa
    34621 gagaccaaac tattgaagcg attgagtcta tcgacgagca ccgcattatc ggtttacagt
    34681 ggcatccaga gtttctggtt aatgaagaag atggcaattt agaattattt gagtatttat
    34741 tgaatgaact gtaacgattg gaacatctgg tcgttctttc ttttattttt tcaaaatttt
    34801 tagaatgtgg catttttacg caaacgtttg aattctgata aaaattggag aaattcgaca
    34861 aaaaacttga aaaaaacgaa ggtaagcgtt atgatagaaa agaagaaata ttggaggaag
    34921 aacatgtcac atattaaatt tgattattca aaagttttag acaaatttgt tgcaccacat
    34981 gaagtggaat acatgcaatc acaagtaaca gcagcagatg aattgatccg taaaggaact
    35041 ggtgctggta gcgacttctt gggatggttg gaccttcctg aaaaatacga ccgcgaagaa
    35101 tttgaccgca tcttgaaagc tgctgagcaa atcaagtcag acagcgatgt tttgattgtg
    35161 atcggtattg gtggatctta ccttggtgca aaagcagcaa tcgacttctt gaatcaccat
    35221 tttgctaact tgcaaacaaa agaagaacgc aaagcgccac aaatccttta cgcaggaaac
    35281 tcaatctcat ctacttacct tgctgacttg gtagagtatg ttgcagacaa agacttctca
    35341 gtaaacgtaa tttctaaatc aggtacaaca actgaaccag cgattgcttt ccgtgtcttt
    35401 aaagaactct tggttaagaa atatggtcaa gaagaagcta acaaacgtat ctatgcaaca
    35461 actgaccgcc aaaagggtgc tgttaaggtt gaagcagacg ctaacagttg ggtaacattt
    35521 gttgttccag atgatatcgg tggacgcttc tcagtattga cagccgttgg tttgcttccg
    35581 atcgcagcat caggagctga catcaaatct cttatggaag gtgcgaatac agctcgcaaa
    35641 gactacactt cagacaaaat ctctgaaaac gaagcttacc aatacgcagc cgttcgtaac
    35701 atcctttatc gtaaaggcta tgcaactgag atcttggtaa actatgagcc atcacttcaa
    35761 tacttctcag aatggtggaa acaattggct ggtgaatcag aaggaaaaga ccaaaaaggt
    35821 atctacccaa cttcagccaa cttctcaact gacttgcatt cacttggtca atttatccaa
    35881 gaaggaactc gtatcatgtt tgaaacagtt gtccgtgttg acaaacctcg taaaaacgtg
    35941 cttattccta ctttggaaga agaccttgac ggacttggtt accttcaagg aaaggacgtt
    36001 gactttgtaa acaaaaaagc aactgacggt gttcttcttg cccacacaga tggtgatgta
    36061 ccaaacatgt atgtgactct tccagagcaa gacgctttca ctcttggtta cactatctac
    36121 ttcttcgaat tggcaattgc cctttcaggt tacttgaatg ctatcaaccc atttgaccaa
    36181 ccaggtgttg aagcttataa acgtaacatg tttgcccttc ttggaaaacc aggatttgaa
    36241 gaattgagca aagaacttaa cgcacgtcta taatagaaga aaagagtggt ttgcccactc
    36301 tttttactct ctttatccat agaaattgga ctcagccaag acttgtgata taatatagaa
    36361 agcaaaaagg cagacgccta gataatagga gaaactatgt taaaagatat ccgcgtacgt
    36421 tacgcaccaa gtccaacagg actactacac atcggaaatg ctcgtacagc attgtttaac
    36481 tacttgtatg cgcgccatca tggtggaaca tttctcatcc gtatcgaaga tactgaccgt
    36541 aaacgccatg tcgaggatgg tgaacgttca caacttgaaa accttcgctg gttaggcatg
    36601 gattgggatg aaagtccaga atcacatgag aattatcgcc agtctgagcg tttggacttg
    36661 tatcaaaaat acattgacca actattagct gaaggaaaag cctataaatc ttacgttaca
    36721 gaagaagagt tggcagctga acgcgaacgc caagaagtag ctggcgaaac accacgctac
    36781 atcaatgaat accttggtat gagtgaagaa gaaaaagcag cttacatcgc agaacgtgaa
    36841 gcagcagggg tcaccccaac tgttcgtttg gctgtcaatg agtcaggtat ctacaagtgg
    36901 catgatatgg tcaaaggcga tattgaattt gaaggtggca atatcggtgg tgactgggtt
    36961 atccaaaaga aagacggtta cccaacttac aactttgccg ttgccatcga tgaccatgat
    37021 atgcaaatct cccatgttat ccgtggagac gaccatattg ctaacacacc aaaacagctc
    37081 atggtttatg aagcacttgg ttgggaagct ccagagtttg gtcacatgac cttgattatc
    37141 aattctgaga ctggtaagaa gttatctaaa cgtgatacca acacccttca gtttatcgaa
    37201 gactaccgta aaaaaggtta tttaccagaa gcagtcttta actttattgc tcttcttggt
    37261 tggaacccag gtggtgaaga tgagattttc tctcgtgaag aactcattaa actttttgat
    37321 gaaaaccgcc tcagcaagtc accagcagcc tttgatcaga aaaaactaga ctggatgagc
    37381 aatgattata tcaagaatac agaccttgaa accatctttc aaatggcaaa accattctta
    37441 gaggaagcag gctgtttgac tgacaaggct gaaaaattag ttgagctcta taaaccacaa
    37501 atgaaatcag tagatgagat tatcccattg acagatcttt tcttctcaga tttcccagaa
    37561 ttgacagaag cagagcgcga agtcatgacg ggtgaaacag ttccaacagt tcttgaagca
    37621 ttcaaagcaa aacttgaagc gatgacagat gatgaatttg tgacagaaaa tatcttccca
    37681 caaattaaag cagtccaaaa agaaacaggt attaaaggga aaaatctttt catgcctatt
    37741 cgtatcgcag tttcaggcga aatgcatggg ccagaattac cagatacaat tttcttgctt
    37801 ggacgtgaaa aatcaattca gcatatcgaa aacatgctaa aagaaatctc taaataaaga
    37861 ggatacaata atggacatct gggaaaagat gtacgaagaa gcacagaaac tatacaatcc
    37921 acatgaagta tcagactttg tttatgccaa tcatgttgta gctgcagtag aagcagaaga
    37981 tggacaaata tttacaggat tctgtatgga gggaacctgt ggtgttttcc atctctgcgc
    38041 agaacgggcg gccctcttca atatgtacca attttcagga caaactaagg ttaagaaagt
    38101 attagccttt cgagataaac caccttatgg cggaagttca gccattcctt gcggtgcttg
    38161 tagagaattc cttttagagc ttaatgctga aaataaagat gcagaattca tgatggacta
    38221 taatataaga aaaacagtta aagtcgcaga actaatccct tattggtggg gagaagaacg
    38281 tgcttctaag tttaatgagc gatagaagag tcagtataat tctggctctt tttactataa
    38341 gttgaaaaaa tgaaaaaaat tagaaaaagt agttgacaaa gtttgaaaag g
//
LOCUS       DAVDHZ010000018        37817 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000018 DAVDHZ010000000
VERSION     DAVDHZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.018"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(14..2566)
                     /locus_tag="VUR46_001080"
     CDS             complement(14..2566)
                     /locus_tag="VUR46_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET5456518.1"
                     /translation="MKSFLKTYRIYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2628..4250)
                     /locus_tag="VUR46_001081"
     CDS             complement(2628..4250)
                     /locus_tag="VUR46_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5456519.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4456..5481
                     /gene="trpS"
                     /locus_tag="VUR46_001082"
     CDS             4456..5481
                     /gene="trpS"
                     /locus_tag="VUR46_001082"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET5456520.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQNIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5633..7111
                     /gene="guaB"
                     /locus_tag="VUR46_001083"
     CDS             5633..7111
                     /gene="guaB"
                     /locus_tag="VUR46_001083"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET5456521.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7162..8259)
                     /gene="recF"
                     /locus_tag="VUR46_001084"
     CDS             complement(7162..8259)
                     /gene="recF"
                     /locus_tag="VUR46_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET5456522.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGYRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQNGKAAVNGN"
     gene            complement(8262..8630)
                     /gene="yaaA"
                     /locus_tag="VUR46_001085"
     CDS             complement(8262..8630)
                     /gene="yaaA"
                     /locus_tag="VUR46_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET5456523.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8789..10039
                     /locus_tag="VUR46_001086"
     CDS             8789..10039
                     /locus_tag="VUR46_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET5456524.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQGSLIERAYQNALLGKSSADFKSWITKLEQV
                     DKDDICRAANNVKLQAIYFMEGIE"
     gene            10036..11319
                     /locus_tag="VUR46_001087"
     CDS             10036..11319
                     /locus_tag="VUR46_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET5456525.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKEYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTSYLFSATDHFLENLDLLDELVTSAHFTEASILREQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTRFYKPVNMSLFLVGDFDVELV
                     QGYFERKELKDLDVQEVVREKFVLQAVKQTDSMRMEVSSPKLAIGVRGKREVAEADCY
                     RHHVLLKLLFAMMFGWTSDRFQKLYESGKIDASLSLEIEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11361..12182
                     /locus_tag="VUR46_001088"
     CDS             11361..12182
                     /locus_tag="VUR46_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5456526.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKGPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12193..12738
                     /gene="pgsA"
                     /locus_tag="VUR46_001089"
     CDS             12193..12738
                     /gene="pgsA"
                     /locus_tag="VUR46_001089"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET5456527.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12735..13562
                     /locus_tag="VUR46_001090"
     CDS             12735..13562
                     /locus_tag="VUR46_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET5456528.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13547..14386
                     /locus_tag="VUR46_001091"
     CDS             13547..14386
                     /locus_tag="VUR46_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET5456529.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14379..15173
                     /locus_tag="VUR46_001092"
     CDS             14379..15173
                     /locus_tag="VUR46_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET5456530.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15232..16050
                     /gene="mreC"
                     /locus_tag="VUR46_001093"
     CDS             15232..16050
                     /gene="mreC"
                     /locus_tag="VUR46_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET5456531.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSISKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16050..16544
                     /gene="mreD"
                     /locus_tag="VUR46_001094"
     CDS             16050..16544
                     /gene="mreD"
                     /locus_tag="VUR46_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET5456532.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16638..17816
                     /locus_tag="VUR46_001095"
     CDS             16638..17816
                     /locus_tag="VUR46_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5456533.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18040..18819
                     /gene="rpsB"
                     /locus_tag="VUR46_001096"
     CDS             18040..18819
                     /gene="rpsB"
                     /locus_tag="VUR46_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET5456534.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            18898..19938
                     /locus_tag="VUR46_001097"
     CDS             18898..19938
                     /locus_tag="VUR46_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET5456535.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20184..20507
                     /gene="tnpB"
                     /locus_tag="VUR46_001098"
     CDS             20184..20507
                     /gene="tnpB"
                     /locus_tag="VUR46_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET5456536.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(20648..20956)
                     /locus_tag="VUR46_001099"
                     /pseudo
     CDS             complement(20648..20956)
                     /locus_tag="VUR46_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20947..21345
                     /locus_tag="VUR46_001100"
     CDS             20947..21345
                     /locus_tag="VUR46_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5456537.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(21542..22462)
                     /gene="cysK"
                     /locus_tag="VUR46_001101"
     CDS             complement(21542..22462)
                     /gene="cysK"
                     /locus_tag="VUR46_001101"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET5456538.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(22747..23382)
                     /locus_tag="VUR46_001102"
     CDS             complement(22747..23382)
                     /locus_tag="VUR46_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET5456539.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYASSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            23438..24736
                     /locus_tag="VUR46_001103"
     CDS             23438..24736
                     /locus_tag="VUR46_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5456540.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            24733..25395
                     /locus_tag="VUR46_001104"
     CDS             24733..25395
                     /locus_tag="VUR46_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET5456541.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            25475..26023
                     /gene="raiA"
                     /locus_tag="VUR46_001105"
     CDS             25475..26023
                     /gene="raiA"
                     /locus_tag="VUR46_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET5456542.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            26159..28132
                     /locus_tag="VUR46_001106"
     CDS             26159..28132
                     /locus_tag="VUR46_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET5456543.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDHVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSCSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            28129..28581
                     /gene="rplI"
                     /locus_tag="VUR46_001107"
     CDS             28129..28581
                     /gene="rplI"
                     /locus_tag="VUR46_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET5456544.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            28625..29977
                     /gene="dnaB"
                     /locus_tag="VUR46_001108"
     CDS             28625..29977
                     /gene="dnaB"
                     /locus_tag="VUR46_001108"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET5456545.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            29979..30245
                     /locus_tag="VUR46_001109"
     CDS             29979..30245
                     /locus_tag="VUR46_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456546.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            30334..31680
                     /gene="cbpD"
                     /locus_tag="VUR46_001110"
     CDS             30334..31680
                     /gene="cbpD"
                     /locus_tag="VUR46_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET5456547.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      31763..31865
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            31936..32226
                     /locus_tag="VUR46_001111"
     CDS             31936..32226
                     /locus_tag="VUR46_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET5456548.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            32189..32947
                     /locus_tag="VUR46_001112"
     CDS             32189..32947
                     /locus_tag="VUR46_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456549.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            32986..33993
                     /locus_tag="VUR46_001113"
     CDS             32986..33993
                     /locus_tag="VUR46_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5456550.1"
                     /translation="MKKTWKVFLTVLTALVAVVLVACGQGTASKDNKEAELKKIDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            33993..34721
                     /locus_tag="VUR46_001114"
     CDS             33993..34721
                     /locus_tag="VUR46_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456551.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENLKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            34840..35298
                     /locus_tag="VUR46_001115"
     CDS             34840..35298
                     /locus_tag="VUR46_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET5456552.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            35300..37732
                     /locus_tag="VUR46_001116"
     CDS             35300..37732
                     /locus_tag="VUR46_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5456553.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQAHSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKI
                     GVKADQLKFDIA"
BASE COUNT        11788 a         6220 c         8197 g        11612 t
ORIGIN      
        1 actagtcgat tttttatgcc ttagatgact ttcgtctgtg attatagatt ccaaatagta
       61 agagagaagt aaaggaacag attgctccag taataaaacc attgggaatg aaggaaagtg
      121 taatagttcc tttccccttg ggaatgtcaa ctttcataaa tccagtttga gcttgtttaa
      181 tttctatttt cttaccatct tggtaggcag accaaccttt gtcataagga atggtgaaga
      241 aaatagatgt atcttgttgg acatcatatg tagcaaaaac cttgttttta gaagttgata
      301 ctgtgacagg ttgttcttta attttttgaa ttgcctcggt gaaagttttg gtatctaaac
      361 gatagaaggt aggagattca aatgatactt gtgaatttcc agggaaacta acattgatat
      421 tgaaagtttt tttctcttta gtatatccta gattaaagaa ggagaagaca ttatcagttg
      481 taaaagtctt tttttcacca tttacaagga tgtcaacctt cttttgttta tcgttagaaa
      541 agtgaaggtt tatgaaagag agataaactt ggctgttttc tggaacttca atttgatact
      601 ggattgctgc atcttcattt gaagaacttg tgacactaat caaatcatta gtattttcta
      661 ttttttctgt tttttcataa ggtattggag aaaaataatc aaaattgacg ttagcaagtt
      721 gatttaaaaa tgaggcctga ttatccaagg tatgttcatt gaacttgaca tcattgtaaa
      781 cagattgact agcaactgca atcggaagag agtattgatt ttcatatagg gtaagattat
      841 ctttttgata gatatcttta aagccatact tatcgatagg actgtctgag atattgtact
      901 ggataccaaa taaactatca gccaaaatac tattatttgc atatcggaga ttgagattag
      961 tcccagagga tttaaaacca agtttatcta aagtagagct tgatgaacga tttcgaacag
     1021 atgaaaattg agagattcca ttgtagttga atttcatact gtcatttcct gtctgagttt
     1081 gtagtttttc agtacgagta aattgatttc caatatatgt tgagaaagat tccatagctg
     1141 ggatatctcg actataagca cttcgagaag caaatcccca ttccttagca attccgtcca
     1201 tttgagatga agcatttaaa ctcatttcaa ccagtataaa taaagagatt agaatggcaa
     1261 atagattcac agatataaac tttttgataa ctgcaaggag taaaagagaa tagacaacca
     1321 aaaattcaag agtaagcaga atattcaaat ctgttaaaaa agaataatgc gattttagat
     1381 agatggtagc taaaaatcct gctactacaa gaaaaagcga aactaaaaaa ttccagactt
     1441 taagttcttt cagacgcttt aagacttctg ctgctgtgta aattaacaag gtagagaaaa
     1501 tccaagcata gcgatgtaaa aacatgtttg gagtatgcat gccttgccaa aataagtcaa
     1561 gagcttctat gtaaaagctt gcaattagaa atgcaaagaa tattacatat atgagtttca
     1621 cgtgaaactt aatagatttc agcgtaaaaa ataaaatggt caaaataaag ggaagtagtc
     1681 caacaaaaat cattgggatg gccccatact ttgttgtgtc aaaggaacca atgaattgct
     1741 tagcaaagag atcaagatac cagctacttt cagtttgaaa ctttgtaact tcagtcaatt
     1801 tttccccatg tgtctgtaaa tcaaatagag tgggaagagt cataatcaaa ctagccatac
     1861 cagctaaaaa ggagataact atgaaatcaa gaacagatga ttttcgagtc ttaaagtccc
     1921 acgaaatttg acagagatac cagaaaataa gaaacaatac tgtcatatat ccaaaataat
     1981 aattttgaat aaataagatt gacagacttg taaagtacaa taggagtttc ttttcagtta
     2041 tcagtagatg taaaccagtt ataattaaag gaatcaagat aaaaacatct agccaggttt
     2101 ttatctctaa ttgactgaca gtgaaactca tcagagcata ggaagtagat aaggctagtt
     2161 ttaaagtctg agggatagat tgaaacaatt tattcaaact aaaaaaggtt gacagaccaa
     2221 tcaatccaaa ttttaagaga gtggtcagat agacagcatc tggcatattc gttagatcaa
     2281 aaaagtaaac tagaggcgcg agaaaactac ccaagtaata actagatagg gcatagaagt
     2341 ttagccctag accacttgta aaggtgtaaa acagactact atttccatgt aggatatttc
     2401 gtaaggctac atcaaaaata acgtattgat gaaagccatc tcctaataga ggagagttgt
     2461 cgctattcca gtagatacct tgagatagat atactccaga cataatcact acaggaatga
     2521 tgaaagaaat aaaatagatt cgatatgttt ttaaaaatga tttcatgtta cctcgtagaa
     2581 tgatagaaaa ctcagttggt taacccaact gagttttgaa gttttattta gtctttccaa
     2641 agttctttaa cttttgcttg tacttctgca ttttctagga attcatcgta ggtttcatcg
     2701 atacggtcaa tgacgccatt tttagataag acaatgatat ggttagccaa agtttgaata
     2761 aactcgtggt catggctggc aaagatgatt gattctttaa agtttttcaa tccatcattc
     2821 aagcttgaga tagattccaa gtccaagtga tttgttggat catcaagtac aaggacattt
     2881 gattttaaga gcatgagttt tgaaagcatg acacgaactt tttctccccc tgacaagaca
     2941 tttacaggtt tgttaacttc atctccagag aagagcatac ggccgaggaa accacgtagg
     3001 aaagtattgt catcttcttc tttacttgcg aattgacgca accagtcaag aattgattct
     3061 cctcctgcaa aatcagctga gttatctttt ggtaggtaag attgactagt tgtaactccc
     3121 cacttgacag ttccttcata gtcaatatct cccatgattg cacgaattaa tgcagtcgtt
     3181 tgaatatcat tttgtccaat aagtgccgtc ttatcatctg gacgcaagat gaaactaata
     3241 ttatccaaga tagtttcacc atcaatcttt acagttagat tttctactgt caagagatca
     3301 ttaccaatct cacgttccgc tttaaagttg ataaatggat atttacgact agatggtaca
     3361 atctcttcta gctcaatctt atcaagcatt ttcttacgtg atgttgcctg ccttgactta
     3421 gaagcattgg cagagaaacg agcaacgaat tcttgcaatt gtttaatttt ttcttctgct
     3481 ttagcattac ggtctgctag caatttagca gcaagctcag aagattcctt ccagaagtcg
     3541 tagtttccga catagagttt gatttttcca aagtcaaggt cggccatgtg agtacaaact
     3601 ttgtttaaga agtgacggtc gtgggatact acgataactg tgttatcaaa gtcaatcaag
     3661 aagtcttcta accaagtaat cgattggata tccaaaccgt tagtaggctc gtccaagaga
     3721 agaacatctg gtttaccaaa aagtgctttg gcgaggagaa cctttacttt ttcaccgttg
     3781 gccaattcgc tcatgttttg gtagtgtaat tcttctggaa tgtttaggtt ttgaagtagt
     3841 tgagaggctt cactctctgc ttcccaacct ccaagttcgg caaattctcc ttcgagttcg
     3901 gcagcacgaa ccccgtcctc gtctgagaaa tcttccttca tgtagatagc atctttctct
     3961 ttcatgatgc tataaagttt ttcatttccc atgataacga catcaatggc acgttcatct
     4021 tcgtagtcaa agtgattttg acgaagaaca gagagacgtt catctggacc aagagagatg
     4081 tgaccagtag taggttcgat atctccagct aaaattttta aaaaggttga ttttccggca
     4141 ccattagcac cgattaatcc gtaagtattt ccttctgtaa atttgatatt gacatcatca
     4201 aaaagtttgc gatcactaaa acgtagtgaa acatcagata ctgtaagcaa tatttttctc
     4261 ctatatgtgt aatatattta ttatactaga aaatacagaa atattcaaat ttttatttgt
     4321 caattttgtg taaattatat ttacagtatc ctttacacaa atctgtaaaa agcaaggctg
     4381 atttattttg ataaattacg gttatttcat taaaaaaatg ctataattga aaggactata
     4441 tcgaaggaga acaaaatgac taaacccatt attttaacag gagaccgtcc aacaggaaaa
     4501 ttgcatattg gacattatgt tggaagtctc aaaaatcgag tattattaca ggaagaggat
     4561 aagtatgata tgtttgtgtt cttggctgac caacaagctt tgacagatca tgccaaagat
     4621 cctcaaaaca ttgtagagtc tatcggaaat gtggctttgg attatcttgc agttggattg
     4681 gatccaaata agtcaactat ttttattcaa agccagattc cagagttggc tgagttgtct
     4741 atgtattata tgaatctagt ttcgttagca cgtttggagc gaaatccaac agtcaagaca
     4801 gagatttctc agaaaggatt tggagaaagc attccgacag gattcttggt ctatccaatc
     4861 gctcaagcag ctgatatcac agctttcaag gctaattatg ttcctgttgg gacagatcag
     4921 aaaccaatga ttgagcaaac tcgtgaaatt gttcgttctt ttaacaatgc atataactgt
     4981 gatgtcttgg tagagccgga aggtatttat ccagaaaatg agagagcagg gcgtttgcct
     5041 ggtttagatg gaaatgctaa aatgtctaaa tcactaaata atggtattta tttagctgat
     5101 gatgcggata ctttgcgtaa aaaagtaatg agtatgtata cagatccaga tcatatccgc
     5161 gttgaggatc caggtaagat tgagggaaat atggttttcc attatctaga tgtttttggt
     5221 cgtccagaag atgctcaaga aattgctgat atgaaagaac gttatcaacg aggtggtctt
     5281 ggtgatgtga agaccaagcg ttatctactt gaaatattag aacgtgaact gggtcctatt
     5341 cgtgagcgcc gtattgaatt tgctaaggat atgggagaag tttataatat gattcaaaaa
     5401 ggtagtgaaa gagcgcgtga agttgcgggt caaaccctat ctgaggtaaa aggggcaatg
     5461 ggacttcatt actttaacta agtttatttt acaagaaact atcatttcta tctcgaagaa
     5521 aagatagttt tttatttacc cctgtaacat ttgacaaatt tttatagaat ggtatgatag
     5581 atacaatata aaaagaatca agctcaaaaa gaaagaaaag aggaaacttc gaatgtctaa
     5641 ttgggacact aaatttttga aaaaaggttt tacctttgat gatgtattgc ttattccagc
     5701 tgaaagtcat gtgttgccta acgatgcaga tttaacaact aaattggcag ataatttgac
     5761 tttaaatatc ccaattatta ccgctgccat ggacacagtt acagagagtc aaatggccat
     5821 tgctattgct cgtgcaggtg gtctcggagt tatccataaa aacatgtcaa ttgctcaaca
     5881 agcagacgag gttcgtaagg taaaacgttc tgaaaatgga gttattattg atccgttctt
     5941 cttgacgcct gaacatacaa ttgctgaagc agatgagctt atgggtcgtt accgcatcag
     6001 tggtgttcca gttgttgaaa cacttgaaaa tcgtaaattg gttggtattt tgacaaaccg
     6061 agatcttcgt tttatttcag attataatca accaatttca aaccatatga ctagtgaaaa
     6121 tcttgttact gctcctgtgg gtacggatct tgcaacggct gagagtattc ttcaagagca
     6181 tcgtattgaa aaacttccgt tggtcgatga agaaggcagt ctttctggtt tgatcactat
     6241 caaagatatt gaaaaagtta ttgagtttcc aaatgcggct aaagatgagt ttggtcgtct
     6301 tctagttgca ggtgcagtag gtgttacttc agatacattt gaacgtgcag aggctctttt
     6361 tgaggcagga gcggatgcga ttgttattga tactgcacat ggtcattctg caggtgtctt
     6421 gcgtaaaatt gccgagattc gtgctcattt cccagatcgg actttgattg ctggaaatat
     6481 tgctactgct gaaggtgcac gtgcccttta tgaagcgggt gtagacgttg ttaaggttgg
     6541 tattggacca ggttctatct gtactactcg tgtgattgct ggtgttggtg ttccgcaagt
     6601 aacagctatc tacgatgctg cagctgttgc gcgcgaatat ggtaaaacga ttattgctga
     6661 cggtgggatc aagtattctg gagatattgt aaaagcactt gctgcaggtg gaaatgctgt
     6721 tatgcttgga tctatgtttg ctggaactga tgaagctcca ggcgaaactg aaatcttcca
     6781 aggacgtaaa ttcaagactt accgtggtat gggatcaatt gctgctatga agaaaggttc
     6841 aagcgaccgt tatttccaag gttctgtcaa tgaagcaaac aagctcgttc cagaaggaat
     6901 tgaaggtcgt gttgcttata aaggagcggc agctgatatt gttttccaaa tgattggtgg
     6961 tattcgctct ggtatgggtt actgtggtgc agctaacctt aaagaactac acgataatgc
     7021 tcaatttatt gaaatgtctg gtgctggttt gaaagaaagc catcctcatg atgtgcaaat
     7081 tactaatgag gcaccaaatt attctatgta aaaaacaatg aaaagaactc cagtgaaaac
     7141 aggagttctt ttacaatgtt gtcaatttcc atttacagca gctttaccat tctgaatagt
     7201 gaagatactt agattttctg gcagattttg aagatggtct aagcttgttg ttgtgataaa
     7261 ggtttggatt gattgagaaa tcgtttctaa taattttaac tgtctagtgt tgtcaagttc
     7321 actcatcaca tcgtcaagca gtaatatcgg agattctgtg gtaatgcttt ccattaattc
     7381 gatttctgct aattttatag agaggacgag actacgatgt tgaccttggc ttccgaaact
     7441 agcatccatc ccatttatat aaaaagaaat gtcatctcga tgaggaccga caccagtatt
     7501 ctttttaaat aaatctctgg atctactttt ttctaaagca attttgaaag attcggataa
     7561 gttttgtttg tcagttatat tgacagaaga ttgataggat attgacaact cttcgatctg
     7621 attagagagt tcaaaatgtt tcttacgccc aaatgattct agttttttta tgaaatctaa
     7681 gcggtgattc attacacgat atccataatc aactagctga tcatctaaca cagaaaggaa
     7741 tgtttcatct attttttgag ctgattttag gtaagtgttt ctttgcttta ggatgtggtt
     7801 ataattggtt aagtcagata agtagattgg cttaatttgc ccaagttcca tatcaatgaa
     7861 ttttcgtcga atcgaaggtg ctcctttaat tagttgtaaa tcttcaggag caaataagac
     7921 aacattcatg tgtcctacat aatctgaaag gcgtgcctgt tttaagtgat taacttttgt
     7981 tacacggcct ttttgtgtta gttcgatttc taggggaatg gatccagttt ttttctgaac
     8041 gagacctgaa agatgaagtt gttcctcatc aaaatgaatg agatttttat ctgttcgagt
     8101 tcgatgacta cgcgttaagg ctaaaaaata gatagcctct aacatgtttg tttttccttg
     8161 tgcattacgt cccaaaaaga cattcaattt aggattaaag tctattttcg tttctttgta
     8221 attacgaaaa gtcttgagag atagatgttg tagccacatg attatctacc agggaatcgt
     8281 ggagcttgtt ggcttttagg tgatgaagca ggtttcgatt tgtctttttt aactccctta
     8341 ttcatctttt tgacaagttt agcgatccgt tctttttcaa ctttatcagc ttggtattca
     8401 tcttgttctt cagaagtagg ttgtgtcaac aagatgtcaa tgttcatgtc agggatgtca
     8461 actttatcgc caatacgaag tttttttcca cgacgactct ctaattccct attaaagtaa
     8521 acagaatgtt cagagagaaa tgatttaata gctcctccgc tatgtgtaat tccaagttct
     8581 ttgagtagtg cttggagggt aataaattct tcaaataatt tgtattccat aattcacctc
     8641 aatctttggt attataccat attttcctaa aaatagtgag agagacagcg agaaatgtaa
     8701 gcgattttta tttcaaaagt gttacaggga acaagaaaat ttcaggtttt cgtgatataa
     8761 tagaagtctg tatataagga ggtaaatcat ggagttagtg catggaattt caacacattt
     8821 tatccaatca aaaaagttta aaacaaacaa aattaccgtg cgttttaccg ctccattatc
     8881 ccttgatacg attgcaggtc acatgttgag tgcaagtatg ctagagactg ctaatcagat
     8941 gtaccccact tctcaagatt tgaggagaca cttggccagt ctatacggta cagatatgtc
     9001 aaccaattgt ttcagaagag ggcaaagcca cattatagaa ttgacattta cctatgttcg
     9061 tgatgagttt ttaagtagga aaaacgtgct aacttctcag attttggaac ttgtaaaaga
     9121 aactcttttt tcacccgtag tagttgataa tgggtttgat ccggccttat ttgaaattga
     9181 gaaaaaacaa ttgctagcaa gtttagcagc tgatatggat gattcttttt attttgcaca
     9241 taaagaattg gataaattgt tttttcatga tgaacgtctt caattggaat atagtgattt
     9301 acgaaatcgt attttagctg aaactccaca aagttcttat tcttgtttcc aagaattttt
     9361 agccaatgat cgaatagatt tctttttcct aggtgatttt aatgaggttg aaattcaaaa
     9421 tgtattagaa tcatttggct ttaaaggtcg aaaaggagat gtgaaggttc agtattgtca
     9481 accttattct aatatccttc aggaaggtat ggttcggaaa aatgtgggac aatctatttt
     9541 ggaattaggt tatcattacc gttctaaata tggtgatgag caacatttac ccatgattgt
     9601 aatgaatggt ttacttggtg gatttgctca ctctaagctc tttacaaatg tccgtgaaaa
     9661 tgctggattg gcttatacta tttcaagtca gcttgattta tttagtggat ttttgaggat
     9721 gtatgctggt attgatcgag aaaatcggaa tcaggctcgt aaaatgatga ataatcaact
     9781 gcttgattta aaaaaaggtt attttacaga gcttgagtta gagcagacca aggaaatgat
     9841 tcgtcggtct ttgttacttt ctcaagataa tcaaggttca ttgattgaac gtgcttatca
     9901 aaatgcctta cttggaaaat cttcagcaga ctttaaaagt tggattacaa aactcgagca
     9961 agttgataaa gatgatattt gtagagcagc taataatgtg aaactacaag cgatttactt
    10021 tatggaagga atagaatgac aaaggttgtt tttgaagaaa aatactatcc agctgtaaaa
    10081 gaaatggttt atcgaactcg tttggccaac ggattgacag ttgctctttt gcctaaaaag
    10141 gaatttaaag aggtttacgg gagtgtaact gtacaatttg gttcggtaga tacgcttgtc
    10201 acagaagttg acggagatgt aaaagaatat cctgcgggaa ttgctcattt tcttgaacat
    10261 aaattatttg agagagaaga ttctagtgat ttgatgtctg cttttacgag tctaggtgca
    10321 gatagtaatg cctttacaag ctttacaaaa acaagttatc ttttttcagc aacggatcat
    10381 tttttagaaa atttagattt acttgatgaa ttggtaacat cagcacactt tactgaagct
    10441 tccattttga gagagcagga tattatccag caagaacgag aaatgtatca agatgatcca
    10501 gattcgtgtt tattcttttc aactttagcg aatttgtatc ctggtacacc tttagcaacg
    10561 gatatagttg gaagtgagga gtccatttcc caaatcaatc taactaattt gcaagaaaat
    10621 tttacaagat tttacaaacc tgtaaacatg tctctgtttt tagttggtga ttttgatgta
    10681 gagctagttc agggttactt tgaaagaaaa gaactgaaag acttagatgt tcaggaagta
    10741 gtaagagaaa aatttgtttt acaggctgta aagcaaacag acagtatgag aatggaagta
    10801 tcttctccca aactagcgat tggagttaga ggtaagcgag aagttgctga ggcggattgc
    10861 tatcgacatc atgttttatt aaaattattg tttgcaatga tgtttggttg gacttcggat
    10921 cgttttcaaa agttatatga atcaggtaaa atagatgctt ccttatctct tgaaattgaa
    10981 gtaacaagtc gttttcattt tgtcatgttg acaatggata cgaaagagcc agttgctttg
    11041 tctcatcaat ttaggaaggc tattcgtaat tttacaaagg atttagatat tacagaggaa
    11101 catttagata ttatcaaaag agagatgttt ggcgaatttt tcagtagcat gaactctctt
    11161 gaatttattg caacgcaata tgatgctttt gaaaatggtg agacaatttt tgatttgccg
    11221 aaaattttac aggaaattac tttagaggat gtccttgatg ctggacatca tttaatagat
    11281 gatggtgaca tagttgattt tacaatattc ccatcgtagt aacctattat aatagacact
    11341 agaaagaagg gatgacaagt atgagaaaaa aaacaattgg agaggtttta cgattagcta
    11401 gaatcaatca gggattgagt ttagatgaat tgcagaaaaa gacagaaatc cagttagata
    11461 tgttggaagc aatggaagca gacgatttcg atcaacttcc aagtcctttt tacacgcgtt
    11521 ctttcttgaa aaaatatgca tgggctgttg agttagatga ccaaattgtt ttggatgctt
    11581 atgattctgg gagtatgatt acttatgagg aagtagatgt tgatgaagat gagttgacag
    11641 gtcgtagacg ttcaagtaag aaaaagaaga aaaaaacatc atttttacct ttattttatt
    11701 ttatcctttt tgctttatcg attttaattt ttgtgactta ttatgtttgg aactatattc
    11761 aaactcaacc agaggagcct tctctttcta attacagtgt ggttcaatca acaagttcaa
    11821 ctagctctgt tccccactcc tcaagtagta gttcttctag tatagaatca gctataagtg
    11881 tatcaggcga aggaaatcat gtagaaatcg cttataagac aagtaaggaa acagttaaat
    11941 tgcaattggc agtttcagat gttacaagtt gggtcagtgt ttcagaaagc gaacttgagg
    12001 gcggtgtaac cttatcgcca aagaagaaaa gtgcagaagc aacagttgca actaaaggtc
    12061 ctgtaacaat tacgttaggt gttgtaaaag gtgttgattt gacagtagat aatcagactg
    12121 ttgatttatc gaaattaaca gctcagactg gacaaatcac tgtaaccttt actaaaaatt
    12181 aaggaaaaac gaatgaaaaa agaacaaatt cccaatctct taacaatagg tcgaattctc
    12241 tttataccta tttttatctt tattttaacg ataggaaatt cgatagagag tcatatagtt
    12301 gcagctatta tctttgctgt tgccagtatt accgactatt tagatggata tttagctcgt
    12361 aaatggaatg tggtcagtaa ttttggtaaa tttgcagatc ctatggcgga taagttacta
    12421 gttatgtcgg cttttattat gttgattgag ttaggtatgg ctccggcttg gattgttgca
    12481 gtgattatct gtcgtgagtt agctgtgaca ggtttaaggc ttttattggt tgaaactggt
    12541 ggaacaattt tagcagcagc aatgcctgga aaaattaaaa cttttagtca gatgtttgct
    12601 attattttct tgctattaca ttggactttg cttggtcaag ttctacttta tgtagcctta
    12661 tttttcacta tctactctgg ctatgactat ttcaagggta gtgcctatgt atttaaaggg
    12721 acatttggtt cgaaatgaaa tcaataattg atgtaaaaaa tctttctttt cgctataaag
    12781 aaaatcagaa ctactacgat gtgaaggata ttacgtttca cgtgaaacgt ggagaatggc
    12841 tttcgattgt agggcataat ggtagtggta aatcaacgac ggttcgatta attgatggct
    12901 tactggaagc agaatccgga gagattgtaa ttgatggcca acgtttgact gaggaaaatg
    12961 tttggaatat acgtcgtcaa atcggtatgg tttttcaaaa tccagacaat caatttgttg
    13021 gagcgactgt tgaagatgat gttgcttttg gtttggaaaa tcagggactt tctcgtcaag
    13081 aaatgaaaaa gagagtggaa gaagctctgg atttagttgg catgttggac tttaaaaaga
    13141 gagagccagc gcgtctatca ggtggccaaa agcaacgtgt ggccattgca ggtgttgtag
    13201 ccctaagacc agctatttta atcttagatg aagcaacgag tatgttggat cctgaggggc
    13261 gtagagaact tattgggaca gtaaaaggaa ttcgaaaaga ctatgatatg acggtcattt
    13321 ctattaccca tgatttggaa gaagtcgcca tgagtgatcg cgtattggtc atgaaaaaag
    13381 gggaaattga atcaactagt agtccaaggg agcttttctc tcgaaatgat ttagatcaaa
    13441 ttggattaga cgatcctttt gctaatcaat taaaaaaatc tttgagccag aatggctatg
    13501 atttacctga aaattatttg acagaaagtg agctagagga taagctatgg gaattgctct
    13561 agaaaatgtg aattttacat atcaagaagg tactccctta gcttcagcag ctttgtcgga
    13621 tgtttctttg acgattgaag atggctctta tacagcttta attgggcaca caggtagtgg
    13681 taaatcaact attttacaac tcttaaatgg tttattggtg ccaagtcaag ggagtgtgag
    13741 ggtttttgat accttaatca cctcgacttc taaaaataaa gatattcgcc aaattagaaa
    13801 acaggttggc ttggtatttc agtttgctga aaatcagatt tttgaagaaa cggttttgaa
    13861 ggacgttgct tttggaccgc aaaattttgg agtttctgaa gaagatgctg tgaagactgc
    13921 gcgtgagaaa ctggctctgg ttggaattga tgaatcactt tttgatcgta gtccgtttga
    13981 gctgtcaggg ggacaaatga gacgtgttgc cattgcaggc atacttgcca tggagccagc
    14041 tatattagtc ttagatgagc caacagctgg tctagatcct ctagggagaa aagagttgat
    14101 gaccctgttc aaaaaactcc accagtcagg gatgaccatc gtcttggtaa cgcatttgat
    14161 ggatgatgtt gctgaatatg cgaatcaagt ctatgtaatg gaaaagggac gtttagtaaa
    14221 ggggggcaaa ccaagtgatg tctttcaaga cgttgttttt atggaagaag ttcagttggg
    14281 agtacctaaa attacggcct tttgtaaacg attggctgat agaggcgtgt catttaaacg
    14341 attaccgatt aagatagagg agttcaagga gtcgctaaat ggatagtatg attttagggc
    14401 gttatatccc aggggattcg attgttcacc gattggatcc acgtagcaaa ttgcttgcta
    14461 tgatgctact gattttgatt gtgttttggg ctaataaccc cttgacgaat ctgattcttt
    14521 ttatagcgac agggatattt attgccttgt caggagtatc tctttcattt tttattcagg
    14581 gcttgaagtc tatgtttttc ttgattgcct tcacaactat ttttcaacta tttttcattt
    14641 ctaatgggaa tgttttattt gagttttcgt ttgtgagaat cacggattat gctttgcaac
    14701 aagctgggat tattttttgt cgctttgtat tgattatttt cttttcaact ttgttaacct
    14761 taacaaccat gcctttaagt ttggcatcag ctgtcgaagc tttattagca cctttaaagc
    14821 gtgtgaaagt tccagttcat gaaattggat tgatgctgtc tatgagtttg cgttttgtcc
    14881 caaccttgat ggatgatacg actcggatta tgaatgcaca gaaagctcgt ggagtggatt
    14941 ttggagaagg aagtatcgtt caaaaagtaa aggcgatgat tcccattttg attcctcttt
    15001 ttgcgacaag tttaaaacgt gcagattcct tggctatcgc tatggaagcg cgtggctatc
    15061 agggtggaaa aggcagaagt caataccgac aattgaaatg gactctaaag gatacgctga
    15121 ccattcttgt tattctcgta cttggttgtt gtttattttt cttaaaatct tagtagcttt
    15181 caggaattga taaaaagtta ctgtaacagt ttttgatata aaggtaggga tatgaaccgt
    15241 tttaaaaaat caaaatatgt cattattgtt tttgtcactg ttctgcttgt gtcagctctc
    15301 ttagcgacga cttattcaag tacaattgtg acaaaattag gagatggaat ctcattggtt
    15361 gatagagttg tacaaaaacc ttttcagtgg tttgattctg tcaaatcaga tttggctcat
    15421 ttgacacgaa catataatga aaatgaaagt ttgaagaaac agctttacca attagaagtt
    15481 aaatcaaatg aggtggaaag tttaaagaca gaaaatgaac aactgcgcca attgcttgat
    15541 atgaagtcta aattgcaagc cacaaagact ttagcagcag atgttattat gcgttctccg
    15601 gtatcttgga agcaggagtt gaccttagat gcaggtagat caaaaggtgc ttctgagaac
    15661 atgttagcta ttgcaaatgg tggcttgatt gggagtattt caaaagtaga ggagaactct
    15721 actatagtca accttctgac aaatacggaa aatgctgata agatttctgt taaaattcaa
    15781 catggctcta ctacaattta tggaattatt attggctatg acaaggaaaa tgacgttctt
    15841 aaaattagcc aattaaatag taatagcgat attagtgcgg gagataaggt gactactggt
    15901 ggattaggaa actttaacgt tgctgatatt cctgttggtg aagtggttgc cacaacgcat
    15961 agtacagact atttgacacg agaagtaact gttaaattga gtgcagatac tcataatgta
    16021 gatgtgatag aattagtggg gaattcataa tgagacagtt gaagcgagtt ggagtatttt
    16081 tattgcttcc tttctttgtt ctaattgacg cccatattag ccagcttctg ggctcatttt
    16141 tcccccatgt acatttggct agtcattttc tttttctatt tctcttattt gagacgatag
    16201 aagtatcaga gtatctctac ctagtctatt gttttgttat aggcttggtt tatgatgttt
    16261 actttttcca tctaataggg attacaactc tcttatttat cttattggga gccttccttc
    16321 ataaattgaa tagtgttatt ttgttgaatc gttggacaag aatgctagct atgattgtgc
    16381 tgacattcct gtttgaaatg ggtagttatc ttttggcttt tatggtaggg ttgacagtag
    16441 atagcatgtc gatttttata gtctatagct tggtaccgac gatgatttta aattttttat
    16501 ggattactgt ttttcaattt atttttgaaa aatattatct ataagaacga catataaatg
    16561 taacaaaggc gtaatattta ttaggccttt ttttggtata ctagtattgt ctttaaaaga
    16621 aggagtatct acgtaatatg aagaaaaaaa tcttagcgtc acttttatta agtacagtaa
    16681 tggtttctca agtagctgtt ttaacaactg cgcatgcaga aacgactgat gacaaaattg
    16741 ctgctcaaga taataaaatt agtaacttaa cagcacaaca acaagaagcc caaaaacaag
    16801 ttgaccaaat tcaggagcaa gtatcagcta ttcaagctga gcagtctaac ttgcaagctg
    16861 aaaatgatag attacaagca gaatctaaga aactcgaggg tgagattaca gaactttcta
    16921 aaaacattgt ttctcgtaac caatcgttgg aaaaacaagc tcgtagtgct caaacaaatg
    16981 gagccgtaac tagctatatc aataccattg taaactcaaa atcaattaca gaagctattt
    17041 cacgtgttgc tgcaatgagt gaaatcgtat ctgcaaacaa caaaatgtta gaacaacaaa
    17101 aggcagataa aaaagctatt tctgaaaaac aagtagcaaa taatgatgct atcaatactg
    17161 taattgctaa tcaacaaaaa ttggctgatg atgctcaagc attgactacg aaacaggcag
    17221 aactaaaagc tgctgaatta agtcttgctg ctgagaaagc gacagctgaa ggggaaaaag
    17281 caagtctatt agagcaaaaa gcagcagctg aggcagaggc tcgtgcagct gcggtagcag
    17341 aagcagctta taaagaaaaa cgagctagcc aacaacaatc agtacttgct tcagcaaaca
    17401 ctaacttaac agctcaagtg caagcagtat ctgaatctgc agcagcacct gtccgtgcaa
    17461 aagttcgtcc aacatacagt acaaacgctt caagttatcc aattggagaa tgtacatggg
    17521 gagtaaaaac attggcacct tgggctggag actactgggg taatggagca cagtgggcta
    17581 caagtgcagc agcagcaggt ttccgtacag gttcaacacc tcaagttgga gcaattgcat
    17641 gttggaatga tggtggatat ggtcacgtag cggttgttac agctgttgaa tcaacaacac
    17701 gtatccaagt atcagaatca aattatgcag gtaatcgtac aattggaaat caccgtggat
    17761 ggttcaatcc aacaacaact tctgaaggtt ttgttacata tatttatgca gattaattta
    17821 cagagggact cgaatagagc cctcttttca ggttttaccg tgacaatccc tattaaaaat
    17881 tatatcaaaa tagcttgaaa atattggaaa agtatggtag aatgaaaatt gtcgtgtgaa
    17941 cgataatact cattcttgat gaattgtgaa gcagttgccc ttgggtcgtt ttgcgagttg
    18001 aagtcaagaa gaggaaaaaa acaaaaagga gaaatactca tggcagtaat ttcaatgaaa
    18061 caacttcttg aggctggtgt acactttggt caccaaactc gtcgctggaa tcctaagatg
    18121 gctaagtaca tctttactga acgtaacgga atccacgtta tcgacttgca acaaactgta
    18181 aaatacgctg accaagcata cgacttcatg cgtgatgcag cagctaacga tgcagttgta
    18241 ttgttcgttg gtactaagaa acaagcagct gatgcagttg ctgaagaagc agtacgttca
    18301 ggtcaatact tcatcaacca ccgttggttg ggtggaactc ttacaaactg gggaacaatc
    18361 caaaaacgta tcgctcgttt gaaagaaatt aaacgtatgg aagaagatgg aactttcgaa
    18421 gttcttccta agaaagaagt tgcacttctt aacaaacaac gtgcgcgtct tgaaaaattc
    18481 ttgggtggta tcgaagatat gcctcgtatc ccagatgtga tgtacgtagt tgacccacat
    18541 aaagagcaaa tcgctgttaa agaagctaaa aaattgggaa tcccagttgt agcgatggtt
    18601 gacaccaata ctgatccaga tgatatcgat gtaatcatcc cagctaacga tgacgctatc
    18661 cgtgctgtta aattgatcac agctaaattg gctgacgcta ttatcgaagg acgtcaaggt
    18721 gaggatgcag tagcagttga agcagaattt gcagcttcag aaactcaagc agattcaatt
    18781 gaagaaatcg ttgaagttgt agaaggtgac aacgcttaat ttatacaaat agtaattacc
    18841 taggagggcg gggcttagcc cggctctcct attttcaaaa aatataggag aattaaaatg
    18901 gcagaaatta cagctaaact tgtaaaagag ttgcgtgaaa aatctggtgc cggtgttatg
    18961 gacgctaaaa aagcgcttgt agaaacagac ggtgacatcg aaaaagcgat tgaattgctt
    19021 cgtgaaaaag gtatggctaa ggcagctaag aaagctgacc gtgttgctgc agaaggtttg
    19081 actggtgttt atgttaacgg taatgttgca gcagttattg aagtaaacgc tgaaactgac
    19141 ttcgttgcaa aaaacgctca attcgttgaa ttggtaaata ctacagctaa agtcattgct
    19201 gaaggaaaac ctgctaacaa tgaagaagct cttgctttga taatgccttc aggtgaaact
    19261 cttgaagctg catacgtatc tgcaacagca actatcggag agaaaatctc attccgtcgc
    19321 tttgcattga ttgaaaaaac agacgcacaa cactttggag cataccaaca taacggtgga
    19381 cgtatcggtg ttatttcagt tgttgaaggt ggagacgaag cacttgctaa acaattgtca
    19441 atgcacatcg cagcgatgaa accaacagtt ctttcttaca aagaattgga tgagcaattc
    19501 gttaaagatg agttggcaca attgaatcac gttatcgacc aagacaacga aagccgtgca
    19561 atggttaata aaccagctct tccacacttg aagtatggat caaaagctca attaactgat
    19621 gatgttattg ctcaagctga agctgacatc aaagctgaat tggctgcaga aggcaaacca
    19681 gaaaaaatct gggacaaaat tattccaggt aaaatggatc gcttcatgct tgataacact
    19741 aaagttgacc aagcttacac acttcttgca caagtttaca tcatggatga cagcaagaca
    19801 gttgaagcat accttgaatc agttaacgct tcggtagttg agtttgctcg ctttgaagtt
    19861 ggtgaaggta tcgagaaagc tgcaaacgac ttcgaagctg aagttgcagc tacaatggca
    19921 gcagccttga ataactaata atagaaagga agcaatttgc ttcctttttt gtatagggct
    19981 tatatttttc ctgaaattgt ttttccccca gtctcactcg attagaataa ttaaaacaaa
    20041 aagccctata ataagggcta agtgcattta ggagactata cttcaaattc atagtaagcg
    20101 cgtcataaca aggtatctat cctaattccc caacttccag tatactagat aaaaaataat
    20161 tatcggagga aaggtattgt actatgatga ttcaactaag tgatttaggt caagttcaca
    20221 ttgtttgtgg caagacagat atgaggcagg gaatagactc attagcctat gtagttaaaa
    20281 cccactttga attggattct ttctccggtc aagtctttct cttttgtggt ggacgtaaag
    20341 accgctttaa agtcctttac tgggatggtc aaggattttg gctactatat aaacgctttg
    20401 agaacggaaa actgacttgg ctaagtacag aaaaggatgt caaagctctc acatctgaac
    20461 aagtagactg gcttatgaag ggcttttcta tcactcccca aatatagtgg tttgaaacta
    20521 gaatagtaca cctctgcttc taaaacattg ttagaaatcg atttgactgt cctgttctta
    20581 tttcatttta ctataaattc atcagaaagt cgtgatttct attgaaatga ggactttctt
    20641 tttatactca tctgttttca caaagcattc tagtccatct ccgattaacg atggacttta
    20701 tcacctcctt ctccagtcct tgtataacat cttggagttg attcatgaca tcttccaaaa
    20761 tttgaaaggc tttattctta aatccacgtt tacgaatctc tttccacact tgttcaatgg
    20821 ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc aatattagtc ggaatcttta
    20881 aggtacttga tttatgccat atagcattgt ccataacgag taaaagataa tcatctggat
    20941 aagcttgtga aatctcctat tcctaaagcc cctttagcgc ataactttgg ctcagcttct
    21001 attatcgctc acaccatcca tcagaagttt aatctgaagg tacccaatta tcgccaagaa
    21061 gaagattggg ctaggatggg tttaccaatc acacgtaagg aaatctctaa tcggcatatc
    21121 aagacgagtc aatactattt ggagcccctt tataacctct tgcgagagag actattgact
    21181 cagcccttac ttcatgcgga tgaaacttct tatagggtgc tagagagtga tagtcagctg
    21241 acttactatt ggactttttt gtctgggaaa gctgagaaac aagggattac gctttaccat
    21301 catgtcctaa tcgatttgtt catatcttat ttcaatccat tataaatagt gagaaatatc
    21361 tatcctatct tctagaatgt cttccaaacg tggaaactct cgtaaacaaa gaggttttag
    21421 aggcctattt accatggact aaagttgtac aagaaaagtg caaataagaa atctccagat
    21481 taggaactat ccgtgagttc tctagtctgg agatttttca atagacttcg ttattggacg
    21541 gttacaattc ataaagtgct gtagagagat aacgttcacc gttatctggt gctagggcaa
    21601 ggactttttt acctgtacct aattttttgg caacctcgat ggctccgtag atagctgcag
    21661 ctgaggaaat ccctacaagg aagccttctt ttccaccaat ttcacgtccg agtgcaagag
    21721 cgtcatctga tgttacacga acgataccat cataggcttt agtatcaagt gtatcaggaa
    21781 taaatccagc tgagatacct tgaattttgt gaggaccagg tttttcacca gatagaatag
    21841 cagattcatc tgcttctact gcaaaaactt gaatgttaga attttctgat ttgagtgcat
    21901 gagaaacacc agaaatcgtt ccaccagtac ctactccagc aacaaaggca tctaatccat
    21961 ctttaccgaa agcagctagt atctcagctc ctgttgttct ttcgtgtact tctggattag
    22021 ctggattgtc aaattgaaga ggaaggaaac catcacgttc agcagcgatt tcttgagcct
    22081 tagcaatagc acctttcatt ccctcgctac caggagttag gacgagttca gcaccataag
    22141 cttggataat tttacgtcgt tctacactca tagtttcagg cataacgatg acgactttat
    22201 accctttagc agcacctacc catgaaagtc caataccggt gtttccactt gttgcttcaa
    22261 caatagtaga accaagtttc agaataccat cttgttcagc tttttcaatc atgctaaggg
    22321 caatacggtc ttttacagat gaaccaggat taaatgcttc aagctttata tagacgtctg
    22381 cagcaccttc tggcacgatg ttgttaagtt taacaatcgg tgtttgaccg attaattcag
    22441 taatgttgtt ataaatagac atatgaatac ctctttgtat aagatatctt tagtataacg
    22501 ctatccatac catttgtaaa atatagaaat cctatcgaag cgataggatt tctatatatc
    22561 atagatcaaa gtcattaatt ttcaagtgat tgcgttcagt taattctagt aaataggtgt
    22621 gaaggaaaac gatatcaggt ttcgtttgaa ttgcttcatt ttctagtata ttttggtacg
    22681 catcttttta ttttgctcgc taaagtagtt gtgagaatgt caacgaaacg ctgtattatt
    22741 cattgtttac actaagttta caggaacttc aacctctcgt aaaccttggt cagttaaagt
    22801 gacttttcca ttaaaaaact ccacaagtgc agctttaata gtttcttttt cttctttatc
    22861 aacataaatc atcgtatcga cttgatctgt aaagtttgta tccagctcca tgagatcatg
    22921 ttctttaagg aagttactgt actcttggta ctgagcataa gacatttgaa tagcaatgcc
    22981 agcctgttct tttatttcaa taataccaat ttctttgaca gctaaggcga cactgctggc
    23041 gtaagcacga attagtcctc cagcgcctag tttaatacca ccaaagtagc gtgtcacgac
    23101 cacacagaca ttggtgagat tgtgattttc tagtacccca agcatgggaa caccagcagt
    23161 accactaggc tcaccatcat cacttgtacg tttaatttca ctacgttctc caataataaa
    23221 ggcagagcag ttatgtgtcg ctttgtagtg ttcttttttg atggcagtaa tgaagtcacg
    23281 agcctcttct tcgctataaa cacgcttggc atggcagata aagcgagatt ttttgatttc
    23341 ttcttggact tggccgtcct ctttaattgt cctaaattcc atgatttaat tgtactaaaa
    23401 aatcatctaa agtgctagtt tttacgaata aagaagtatg aaagtaaatt tagattatct
    23461 cggtcgttta tttactgaga atgaattaac agaagaagaa cgtcagttgg cggagaaact
    23521 tccagcaatg agaaaggaga aggggaaact tttctgtcaa cgttgtaata gtactattct
    23581 agaagaatgg tatttgccca tcggtgctta ctattgtcga gagtgcttgc tgatgaagcg
    23641 agtcagaagt gatcaaactt tatactattt tccgcaggag gattttccga agcaagatgt
    23701 tctcaaatgg cgcggccaat taactccttt tcaagagaag gtgtcagagg gactgcttca
    23761 agcagtagac aagcaaaagc caaccttagt tcatgcggta acaggagctg gaaagacaga
    23821 aatgatttat caagtagtgg ctaaagtgat caatgcgggt ggtgcagtgt gtttggctag
    23881 tcctcgcata gatgtttgtt tggagctgta caagcgcctg caacaggatt tttcttgcgg
    23941 gatagctttg ctacatggag aatcggaacc ttattttcga acaccactag ttgttgcaac
    24001 aacccatcag ttattgaagt tttatcaagc ttttgatttg ctgatagtgg atgaagtaga
    24061 tgcttttcct tatgttgata atcccacgct ttaccatgct gtcaagaata gtgtaaagga
    24121 gaatggattg agaatctttt taacagcgac ttcgaccaat gagttagata aaaaggtccg
    24181 tttaggagaa ctaaaaagac tgaatttacc gagacggttt catggaaatc cgttgattat
    24241 tccaaaacca atttggttat cggattttaa tcgctactta gacaagaatc gtttgtcacc
    24301 aaagttaaag tcctatattg agaagcagag aaagacagct tatccgttac tcatttttgc
    24361 ttcagaaatt aagaaagggg agcagttaga agaaatctta caggagcaat ttccaaatga
    24421 gaaaattggc tttgtatctt ctgtaacaga ggatcgatta gagcaagtac aagcttttcg
    24481 agatggagaa ctgacaatac ttatcagtac gacaatcttg gagcgtggag ttaccttccc
    24541 ttgtgtggat gttttcgtag tagaagccaa tcatcgtttg tttaccaagt ctagtttgat
    24601 tcagattggt ggacgagttg gacgaagcat ggatagaccg acaggagatt tgcttttctt
    24661 ccatgatggg ttaaatgctt caatcaagaa ggcgattaag gaaattcaga tgatgaataa
    24721 ggaggctggt ctatgaagtg cttgttatgt gggcagacta tgaagactgt tttaactttt
    24781 agtagtctct tacttctgag gaatgatgac tcttgtcttt gttcagactg tgattctact
    24841 tttgaaagaa ttggggaaga gaactgtcca aattgtatga aaacagagtt gtcaacaaag
    24901 tgtcaagatt gtcaattttg gtgtaaagaa ggagttggag tcagtcatag agcgattttt
    24961 acttacaatc aagctatgaa ggattttttc agtcggtata agtttgatgg agacttcctg
    25021 ttaagaaaag ttttcgcttc atttttaagt gaggagttga aaaagtacaa agagtatcaa
    25081 tttgttgtaa ttcccctaag tcctgataga tatgctaata gaggatttaa tcaggttgag
    25141 ggcttggtag aggcagcagg ctttgagtat ctggatttat tagagaaaag agaagagaga
    25201 gccagttctt ctaaaaatcg ttcagagcgc ttggggacag aacttccttt ctttattaaa
    25261 agtggagtca ctattcctaa aaaaatccta cttatagatg atatctatac tacaggagca
    25321 actataaatc gtgttaagaa actgttggaa gaagctggtg ctaaggatgt aaaaacattt
    25381 tcccttgtaa gatgaggaaa aaatttgcaa aaatagaatg aaagcgttat aataaaatca
    25441 taaaaacaaa aatgtttaga aagaaggtac tcatatgatt aaatatagta tccgtggtga
    25501 aaacctagaa gtaacagaag caattcgtga ttatgtagtt tctaaactcg aaaagatcga
    25561 aaagtacttc caaccagaac aagagttgga tgcccgaatt aacttaaaag tttatcgtga
    25621 aaaaacggct aaagtggaag taacgattcc gcttggatct attactctcc gcgcagaaga
    25681 tgtatctcaa gatatgtatg gttcaattga ccttgtaact gataaaattg aacgtcagat
    25741 tcgtaaaaat aaaacaaaaa tcgagcgtaa aaataaaaat aaggtagcaa ctggtcaatt
    25801 atttacagat gctttggtgg aagattcaaa tgttgtccag tctaaagttg ttcgttcaaa
    25861 acaaattgat ttaaaaccaa tggatttgga agaagcaatt ctacaaatgg atttattggg
    25921 gcatgatttc tttatctatg tggatgttga agatcagaca accaatgtga tttatcgtcg
    25981 tgaggatggc gaaattggtt tgttagaggt taaagaatct taatttcaat atgtgtaaag
    26041 gtaggtttac tgaattgtaa actacctttt tcttataatt gatagaatta ctgattacac
    26101 ttttaaaaag tcgctttttg aggggtatta tggtataatg ggtgccaaga ggttttgaat
    26161 gaaaaaattt tatgtaagtc caatttttcc tattctagta ggattgattg cgtttggagt
    26221 cttatccact ttcattattt ttgttaataa taatctgttg acggttttaa ttttgtttct
    26281 ttttgtagga ggctatgttt ttttatttaa gaaactgaga gtgcattata caaggagtga
    26341 tgtagaacag atacagtatg taaaccacca agcggaagaa agtttgacat ctctattgga
    26401 acaaatgcct gtaggtgtta tgaaattgaa tttatcttct ggagaggttg agtggtttaa
    26461 tccctatgct gaattgattt tgaccaagga agatggtgat tttgatttag aagctgttca
    26521 aacgattatc aaggcttcag taggaaatcc gtctacttat gccaagcttg gtgagaagcg
    26581 ttatgctgtt catatggatg cttcttccgg tgttttgtat tttgtagatg tatccaggga
    26641 acaagccata acagatgaat tggtaacaag tcgaccagtg attgggattg tctctgtgga
    26701 taattatgat gatttggagg atgcaacttc tgagtcagat attagtcaaa tcaatagttt
    26761 tgtagctaat tttatatcag agttttcaga aaaatacatg atgttttctc gtcgggtaag
    26821 tatggatcga ttttatctat ttactgacta cacggtgctt gagggcttga tgaatgataa
    26881 attttctgtt attgatgctt tcagagaaga gtcgaaacag agacagttgc ccttgacctt
    26941 aagtatggga ttttcttatg gcgatggaaa tcatgatgag atagggaaag ttgctttgct
    27001 caatttgaac ttggctgaag tacgtggtgg cgaccaggtg gttgttaagg aaaacgacga
    27061 aacgaaaaat ccagtttatt ttggtggtgg gtctgctgct tcaatcaagc gtacacggac
    27121 tcgtacgcgc gctatgatga cagctatttc agataagatt cggagtgtag atcatgtttt
    27181 tgtagtcggt cacaaaaatt tagacatgga tgctttgggc tctgctgtag gtatgcagtt
    27241 gttcgccagc aatgtgattg aaaatagcta tgctctttat gatgaagaac aaatgtctcc
    27301 agatattgaa cgagctgttt cattcataga aaaagaagga gttacgaagt tgttgtctgt
    27361 taaggatgca atggggatgg tgaccaatcg ttctttgttg attcttgtag accattcaaa
    27421 gacagcctta acattatcaa aagaatttta tgatttattt acccaaacca ttgttattga
    27481 ccaccataga agggatcagg attttccaga taatgcggtt attacttata tcgaaagtgg
    27541 tgcaagtagt gccagtgagt tggtaacgga attgattcag ttccagaatt ctaagaaaaa
    27601 tcgtttgagt cgtatgcaag caagtgtctt gatggctggt atgatgttgg atactaaaaa
    27661 tttcacctcg cgagtaacta gtcggacatt tgatgttgct agctatctca gaacgcgcgg
    27721 aagtgatagt attgctatcc aggaaatcgc tgcgacagat tttgaagaat atcgtgaggt
    27781 caatgaactt attttacagg ggcgtaaatt aggttcagat gtactaatag cagaggctaa
    27841 ggacacgaaa tgctatgata cagttgttat tagtaaggca gcagatgcca tgttagccat
    27901 gtcaggtatt gaagcgagtt ttgttcttgc gaagaataca caaggattta tctctatctc
    27961 agctcgaagt tgtagtaaac tgaatgtaca acggattatg gaagagttag gcggtggagg
    28021 ccactttaat ttggcagcag ctcaaattaa agatgtaacc ttgtcagaag caggtgaaaa
    28081 actgacagaa attgtattaa atgaaataaa ggaaaaggag aaagaagaat gaaagtaatc
    28141 tttttagcag atgttaaagg aaaaggtaaa aaaggcgaaa ttaaggaagt accaacaggg
    28201 tatgcgcaaa actttcttat caaaaagaat ctagccaaag aagcgactgc tcaagctgta
    28261 ggtgaacttc gtggtaaaca aaaatcggaa gaaaaagctc acgctgagat gattgcagaa
    28321 ggaaaagcaa ttaaagcaca acttgaagca gaagaaactg ttgtagaatt tgttgaaaaa
    28381 gttggtccag atggtcgtac ctttggttct attaccaata agaagattgc agaagaattg
    28441 caaaagcaat ttggaattaa gattgataaa cgtcatattc aagtacaagc tccgattcga
    28501 gcggttggtt tgattgatgt gccagtgaaa atctatcaag atatcacaag tgtaatcaat
    28561 cttcgtgtga aagaaggata agtttacacc ttcttgacaa gattgtaaaa ggaagagaag
    28621 tctgatggca gaagtagaag agttacgagt acaacctcaa gatatcttag ctgagcaatc
    28681 cgttttaggg gctatcttta ttgatgagag taaacttgtt tttgtgcgag aatacattga
    28741 gtctcgggac ttttttaagt atgcccatcg tttgattttc caagccatgg tcgatttatc
    28801 cgatcgtggt gatgccatag atgcaacaac ggttcgtact atccttgata atcaaggtga
    28861 tttacagaat attggtggct tgtcttactt ggttgagatt gtcaattctg tgccaacttc
    28921 tgctaatgcg gagtattatg ctaagattgt tgcagaaaaa gcaatgctac gtcgtttaat
    28981 tgccaagttg acagagtctg tcaaccaagc ttacgaagcg tcacaaccag ctgatgaaat
    29041 tattgctcag gcagaaaaag ggctgattga tgtcagtgaa aatgcaaatc gaagcgggtt
    29101 taagaacatt cgagatgtgt tgaatctcaa ctttggaaat ctggaagctc gctcgcaaca
    29161 aacgaccgat attacaggta ttgcgacagg ttatcgtgat ttggatcata tgacaacagg
    29221 acttcatgag gaggagttga ttatcttagc agctcgtcca gcagttggta agacagcatt
    29281 tgccttgaat atcgctcaga atattgggac taagttggac aaaacggttg ctattttttc
    29341 actcgaaatg ggtgcggaaa gcttggtaga ccgtatgtta gctgcagaag gcttggtgga
    29401 gtcacattct atccgtacag ggcaattgac agatgaggag tggcaaaaat atactattgc
    29461 tcagggtaat ctagctaacg ccagtatcta tatcgatgat acgccaggta ttcggattac
    29521 agagattcgt tctcgttctc gtaaattggc tcaagaaact ggaaatcttg gtttgatttt
    29581 gatagactat ttgcaactta tcacgggaac tggtcgagaa aatcgtcaac aagaagtttc
    29641 tgaaatttct cgtcagttga aaatactagc caaggaattg aaggttccag taatcgctct
    29701 gagtcagctt tctcgtggtg tagaacaacg tcaggacaag agaccggtct tgtctgatat
    29761 tcgtgaatct gggtctattg agcaggacgc tgatatcgta gcttttctct atcgcgatga
    29821 ctactatgaa cgtggtggtg aagaagagga gggtatccca aataataagg tggaagttat
    29881 tatcgagaaa aaccgtagtg gagctcgtgg aacagtggaa ttgattttcc aaaaagaata
    29941 caataaattt tcaagtatct caaagaggga ggcataagat gtcagatgca tttacagatg
    30001 tagccaagat gaaaaaaatc aaagaagaaa ttaaggcaca tgagggacaa gtcgtagaaa
    30061 tgactttgga gaatggtcgt aagcgccaaa aaaatagatt gggtaagcta attgaagttt
    30121 atccatccct atttattgtg gagtttgggg atgtggaagg agataaacaa gttaatgttt
    30181 acgttgaatc ctttacttac tcagatattc ttacagaaaa gaatttgatt cattatcttg
    30241 actaaagtga gaaattttct cactttttct tttttctccg aataatttag gtgaaggcaa
    30301 tcatcgcttt atattatttt ttaaggagga agaatgaaaa ttttaccgtt tatagcaaga
    30361 ggaacaagtt attacttgaa gatgtcagtt aaaaagcttg ttcctttttt agtagtagga
    30421 ttgatgctag cagctggtga tagtgtctat gcctattcca gaggaaatgg atcgattgcg
    30481 cgtggggatg attatcctgc ttattataaa aatgggagcc aggagattga tcagtggcgc
    30541 atgtattctc gtcaatgtac ttcttttgta gcctttcgtt tgagtaatgt caatggtttt
    30601 gaaattccgg cagcttatgg aaatgcgaat gaatggggac atcgtgctcg tcgggaaggt
    30661 tatcgtgtag ataatacacc gacgattggt tccattactt ggtctactgc aggaacttat
    30721 ggtcatgttg cctgggtgtc aaatgtaatg ggagatcaga ttgagattga ggaatataac
    30781 tatggttata cagaatccta taataaacga attataaaag caaacacgat gacaggattt
    30841 attcatttta aagatttgga tggtggcagt gttgggaata gtcaatcctc aacttcaaca
    30901 ggcggaactc attattttaa gaccaagtct gctattaaaa ctgaacccct agttagtgca
    30961 actgtgattg attactatta tcctggagag aaggttcatt atgatcaaat tctcgaaaaa
    31021 gacggctaca agtggttgag ttatactgcc tataatggaa gctatcgtta tgttcaattg
    31081 gaggctgtga ataaaaatcc tctaggtaat tctgttcttt cttcaacagg tggaactcat
    31141 tattttaaga ccaagtctgc tatcaaaact gaacccctag ttagtgcaac tgtgattgat
    31201 tactattatc ctggggagaa ggttcattat gatcagatac ttgaaaaaga cggctacaag
    31261 tggttgagtt atacggctta taacggaagt cgtcgctata tacagctaga gggagtgact
    31321 tcttcacaaa attatcagaa tcaatcagga aatatctcta gctatggatc caataatagt
    31381 tcaactgtcg gttggaagaa aataaatggt agttggtatc atttcaaatc aaatggttct
    31441 aaatcaacag gatggctgaa agacggttct agctggtatt atttgaaatt atctggtgaa
    31501 atgcagacag gatggttaaa ggagaatggc tcgtggtatt atctgggtag ttcaggggca
    31561 atgaaaacag gctggtacca ggtctctggt aagtggtatt attcttactc ttcaggcgcc
    31621 ttagctgtta atacgacggt ggatggctac agagtaaaca gtgatggaga acgagtatag
    31681 aaaattggag taggagaaat ttcctgctct tttctgtaag cagtttcctt gacatttttc
    31741 ttattttgcg ctatcatata tacatataat atatgggagt ctgtgtacag tctgagagga
    31801 agtgttaaac ttcgaccgca cctgatctgg gtaatgccag cggagggaac gatacttagt
    31861 ctaattttgc accttttcca tgtatggtaa aggtttttct tttttttaaa aggaaaacga
    31921 gaagaggagg ttcttatgaa agcaagcatt gccttgcaag ttttacccct agcacagggg
    31981 attgatcgga tagctgttat tgatcaggtc attgcttatc tgcaaactca agaagtgacg
    32041 atggtagtga caccatttga aacggtcttg gaaggggagt ttgatgagct tatgcgcatt
    32101 ctaaaagaag cgctggaagt ggcagggcag gaggcagaca atgtctttgc caatgtcaaa
    32161 ataaatgtag gagagatttt aagtattgat gagaaacttg aaaagtatac tgagacgaca
    32221 cattagtcta ttgggctttc tcggagtctt gtcaatctgg cagttagcag gttttcttaa
    32281 acttctcccc aagtttatcc tgccgacacc tcttgaaatt ctccagccct ttgttcgtga
    32341 cagagaattt ctctggcacc atagctgggc gaccttgaga gtggctttac tggggctgat
    32401 tttgggagtt ttgattgcct gtcttatggc tgtgctcatg gatagtttga cttggctcaa
    32461 tgacctgatt taccctatga tggtggtcat tcagaccatt ccgaccattg ccatagctcc
    32521 tatcctggtc ttgtggctag gttatgggat tttgcccaag attgtcttga ttatcttaac
    32581 gacaaccttt cccatcatcg ttagtatttt ggacggtttt aggcattgcg acaaggatat
    32641 gctgaccttg tttagtctga tgcgggccaa gccttggcaa atcctgtggc attttaaaat
    32701 cccagttagc ctgccttact tttatgcagg tctgagggtc agtgtctcct acgcctttat
    32761 cacaactgtg gtatctgagt ggttgggagg ttttgaaggt cttggtgttt atatgattca
    32821 gtctaaaaaa ctgtttcagt atgataccat gtttgccatt attattctgg tgtcgattat
    32881 cagtcttttg ggtatgaagc tggtcgatat cagtgaaaaa tatgtgatta aatggaaacg
    32941 ttcgtagaat tagaatgttt ctgaaaaaga aaagaggaaa tcaaaatgaa gaaaacatgg
    33001 aaagtgtttt taactgtttt aacagctctt gtagctgtcg tgcttgtagc ttgtggtcaa
    33061 ggaactgctt ctaaggacaa caaagaagca gaactcaaga agatcgactt tatcctagac
    33121 tggacaccaa acactaacca cacagggcta tatgttgcca aggaaaaagg ttatttcaaa
    33181 gaagctggag tggatgttga tttgaaattg ccaccagaag aaagttcttc tgacttggtt
    33241 atcaacggaa aggcaccatt tgcagtatat ttccaagact acatggctaa gaaattggaa
    33301 aaaggagcag gaatcactgc cgttgcagct attgttgaac acaatacatc aggaatcatc
    33361 tctcgtaaat ctgataatgt aagcagtcca aaagacttgg ttggtaaaaa atatgggaca
    33421 tggaatgacc caactgaact tgctatgttg aaaaccttgg tagaatctca aggtggagac
    33481 tttgagaagg ttgaaaaagt accaaataac gactcaaact caatcacacc gattgccaat
    33541 ggcgtctttg atactgcttg gatttactac ggttgggatg gtatccttgc taaatctcaa
    33601 ggtgtagatg ctaacttcat gtatttgaaa gactatgtca aggaatttga ttactactca
    33661 ccagttatca tcgcaaacaa cgactacctc aaagacaaca aagaagaagc tcgtaaagtc
    33721 atccaagcca tcaaaaaagg ttaccaatat gccatggaac atccagaaga agctgcagat
    33781 attctcatca agaatgcacc tgaactcaag gaaaaacgtg actttgtcat cgaatctcaa
    33841 aaatacttgt caaaagaata cgcaagcgac aaggaaaaat ggggtcaatt tgacgcagct
    33901 cgctggaatg ctttctacaa atgggataaa gaaaatggta tccttaaaga agacttgaca
    33961 gacaaaggct tcaccaacga atttgtgaaa taatgacaga aattagacta gagcacgtca
    34021 gttatgccta tggtcaggag aggattttag aggatatcaa cctacaggtg acttcaggcg
    34081 aagtggtttc catcctaggc ccaagtggtg ttggaaagac cactctcttt aatctaatcg
    34141 ctgggatttt agaagttcag tcagggagaa ttgtccttga tggtgaagaa aatctcaagg
    34201 ggcgcgtgag ttatatgttg caaaaggatc tgctcttgga gcacaagacg gtgcttggaa
    34261 atatcattct gcccctcttg attcaaaagg tggataaggc agaagctatt tcccgagcgg
    34321 ataaaattct tgcgaccttc cagctgacag ctgtaagaga caagtatcct catgaactta
    34381 gcggtgggat gcgccagcgt gtagccttac tccggaccta cctttttggg cacaagctct
    34441 ttctcttaga tgaggccttt agcgccttgg atgagatgac aaagatggaa ctccacgctt
    34501 ggtatcttga gattcacaag cagttgcagc taacaaccct gatcatcacg catagtattg
    34561 aggaggccct caatctcagc gaccgcatct atatcttgaa aaatcgccct gggcagattg
    34621 tttcagaaat taaactagat tggtctgaag atgaggacaa ggaagttcaa aagattgcct
    34681 acaaacgtca aatcttggca gaattaggct tagataagta gaaaaatagg gagttggtga
    34741 agattatcct ttaccagcgc cctttttctt ttaaaaatga gaaaatttcg gtataatagt
    34801 caaacaaggt caaggtttaa agagagaggt gggtttgtta tgagatttaa aaatacatcg
    34861 gatcatattg aggcctacat caaggcgatt ttagatcaat ctggtatcgt ggagttgcaa
    34921 cggagtcagt tggcagatac ctttcaggtt gttcctagtc agattaacta cgtgatcaag
    34981 acacgcttta cggaaagtag aggctacttg gttgaaagta agcgtggtgg cggaggctac
    35041 attcgtatag gacggattga gttttctagt catcatgaaa tgctccggga gctgctttac
    35101 tcgattggtg agcgagtcag tcaagaaatt tatgaggata ttctccagct tttggttgag
    35161 caggaattga tgaccaagca ggagatgaat ttgctagaat cagtagcttt ggatcgcgtt
    35221 ttaggagaag aagctccagt tgttcgagca aacatgctac gtcagatcat acaagaggta
    35281 gatagaaaag ggaagtaaga tgaactattc aaaagcattg aatgaatgta tcgaaagtgc
    35341 ctacatggtt gctggacatt ttggagctcg ttatctagag tcgtggcact tgttgattgc
    35401 catgtctaat cacagttata gtgtagcagg ggcaacttta aatgattatc cgtatgagat
    35461 ggaccgttta gaagaggtgg ctttggaact gactgaaacg gactatagcc aggatgaaac
    35521 ctttacggaa ttgccgttct cccgtcgttt gcaggttctt tttgatgaag cagagtatgt
    35581 agcgtcagtg gtccatgcta aggtactagg gacagagcac gtcctctatg cgattttgca
    35641 tgatggcaat gccttggcga ctcgtatctt ggagagggct ggtttttctt atgaagacaa
    35701 gaaagatcag gtcaagattg ctgctcttcg tcgaaattta gaagaacggg caggctggac
    35761 tcgtgaagat ctcaaggctt tacgccaacg ccatcgtaca gtagctgaca agcaaaattc
    35821 tatggccaat atgatgggca tgccgcagac tcctagtggt ggtcttgagg actatacgca
    35881 tgatttgaca gagcaagcgc attctggcaa gttagaacca gtcatcggtc gggacaagga
    35941 aatctcacgt atgattcaaa tcttgagccg taagactaag aacaaccctg tcttggttgg
    36001 ggatgctggt gtcgggaaaa cagctctggc ccttggtctt gcccagcgta ttgctagtgg
    36061 tgacgtgcct gcggaaatgg ctaagatgcg cgtgttagaa cttgatttga tgaatgtcgt
    36121 tgcagggaca cgcttccgtg gtgactttga agaacgcatg aataatatca tcaaggatat
    36181 tgaagaagat ggccaagtca tcctctttat cgatgaactc cacaccatca tgggttctgg
    36241 tagcgggatt gattcgactc tggatgcggc caatatcttg aaaccagcct tggcgcgtgg
    36301 aactttgaga acggttggtg ccaccactca ggaagaatat caaaaacata tcgaaaaaga
    36361 tgcggcactt tctcgtcgtt tcgctaaagt gacgattgaa gaaccaagtg tggcagatag
    36421 tatgactatt ttacaaggtt tgaaggcgac ttatgagaaa catcaccgtg tacaaatcac
    36481 agatgaagcg gttgaaacag cggttaagat ggctcatcgt tatttaacca gtcgtcactt
    36541 gccagactct gctatcgacc tcttggacga agcagcagca acagtgcaaa ataaggcaaa
    36601 gcatgtaaaa gcagacgatt cagatttgag tccagctgac aaggccctga tggatggcaa
    36661 gtggaaacag gcagcccagc taatcgcaaa agaagaggaa gtacctgtct acaaagactt
    36721 ggtgacagag tctgatattt tgaccacctt gagtcgcttg tcaggaatcc cagttcaaaa
    36781 actgactcag actgacgcta agaaatatct aaatcttgaa gcagaactcc ataaacgggt
    36841 tatcggtcaa gatcaagctg tttcaagtat tagtcgtgcc attcgccgta atcagtcagg
    36901 aattcgcagt cacaagcgtc cgatcggttc ctttatgttc ctaggaccca caggtgtcgg
    36961 gaaaactgaa ttagccaagg ctctggcaga agttcttttt gacgacgaat cagcccttat
    37021 ccgctttgat atgagtgagt atatggagaa atttgcagct agtcgtctca acggagctcc
    37081 tccaggctat gtaggatatg aagaaggtgg ggagttgaca gagaaggttc gcaataaacc
    37141 ctattccgtt ctcctctttg atgaggtaga gaaggcccac ccagatatct ttaatgttct
    37201 cttgcaggtt ctggatgacg gtgtcttgac agatagcaag ggacgcaagg tcgatttttc
    37261 aaataccatt atcattatga catcgaatct aggtgcgact gcccttcgtg atgataagac
    37321 tgttggtttt ggggctaagg atattcgttt tgaccaggaa aatatggaaa aacgcatgtt
    37381 tgaagaactg aaaaaagctt atagaccgga attcatcaac cgtattgatg agaaggtggt
    37441 cttccatagc ctatctagtg accatatgca ggaagtggtg aagattatgg tcaagccttt
    37501 agtggcaagt ttggctgaaa aaggcattga cttgaaatta caagcttcag ctctgaaatt
    37561 gttagcaaat caaggatatg acccagagat gggagctcgc ccacttcgca gaaccctgca
    37621 aacagaagtg gaggacaagt tggcagaact cctcctcaag ggagaactgg tagcaggtaa
    37681 gactctcaag attggtgtca aagcagacca gttaaaattt gatattgcat aaaaatggag
    37741 aatcaggagc aatcctgatt tttttatatt tatttttata aaaccaaagg aaacaagttg
    37801 acaatatgta aatgttg
//
LOCUS       DAVDHZ010000019        37426 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000019 DAVDHZ010000000
VERSION     DAVDHZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.019"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            91..161
                     /locus_tag="VUR46_001117"
     tRNA            91..161
                     /locus_tag="VUR46_001117"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:123..125,aa:Cys,seq:gca)
     gene            complement(359..1690)
                     /locus_tag="VUR46_001118"
     CDS             complement(359..1690)
                     /locus_tag="VUR46_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET5456554.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(1981..2805)
                     /gene="endA"
                     /locus_tag="VUR46_001119"
     CDS             complement(1981..2805)
                     /gene="endA"
                     /locus_tag="VUR46_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET5456555.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(2844..3032)
                     /locus_tag="VUR46_001120"
     CDS             complement(2844..3032)
                     /locus_tag="VUR46_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET5456556.1"
                     /translation="MNKKSGYVIKRLLLVILVLILGLLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(3025..4308)
                     /gene="murA"
                     /locus_tag="VUR46_001121"
     CDS             complement(3025..4308)
                     /gene="murA"
                     /locus_tag="VUR46_001121"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET5456557.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASERETVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(4332..4562)
                     /locus_tag="VUR46_001122"
     CDS             complement(4332..4562)
                     /locus_tag="VUR46_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET5456558.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(4620..5657)
                     /locus_tag="VUR46_001123"
     CDS             complement(4620..5657)
                     /locus_tag="VUR46_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET5456559.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMVYAWLTPFTDIRSVQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPALRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGGAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(5641..6129)
                     /gene="coaD"
                     /locus_tag="VUR46_001124"
     CDS             complement(5641..6129)
                     /gene="coaD"
                     /locus_tag="VUR46_001124"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET5456560.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(6119..6658)
                     /gene="rsmD"
                     /locus_tag="VUR46_001125"
     CDS             complement(6119..6658)
                     /gene="rsmD"
                     /locus_tag="VUR46_001125"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET5456561.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(6723..7715)
                     /locus_tag="VUR46_001126"
     CDS             complement(6723..7715)
                     /locus_tag="VUR46_001126"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET5456562.1"
                     /translation="MKKSFIHQQEEISFVKNTLTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(7826..8509)
                     /locus_tag="VUR46_001127"
     CDS             complement(7826..8509)
                     /locus_tag="VUR46_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET5456563.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFFASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(8565..9305)
                     /locus_tag="VUR46_001128"
     CDS             complement(8565..9305)
                     /locus_tag="VUR46_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET5456564.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            9339..9617
                     /locus_tag="VUR46_001129"
     CDS             9339..9617
                     /locus_tag="VUR46_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET5456565.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYPDFKIAN"
     gene            9695..10621
                     /gene="yidC"
                     /locus_tag="VUR46_001130"
     CDS             9695..10621
                     /gene="yidC"
                     /locus_tag="VUR46_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET5456566.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFASQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIINYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(10696..11490)
                     /gene="pflA"
                     /locus_tag="VUR46_001131"
     CDS             complement(10696..11490)
                     /gene="pflA"
                     /locus_tag="VUR46_001131"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET5456567.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(11604..12866)
                     /locus_tag="VUR46_001132"
     CDS             complement(11604..12866)
                     /locus_tag="VUR46_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET5456568.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYTRELGATINLDAFEDIEHLERAAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTPAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKKTYRTYLGVDASAINLMRPAMYGAYHHITNLTHPDGPAEVVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     VRQIRRAERPKDYFATLYGFDFEEESEK"
     gene            complement(12933..13760)
                     /gene="purR"
                     /locus_tag="VUR46_001133"
     CDS             complement(12933..13760)
                     /gene="purR"
                     /locus_tag="VUR46_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET5456569.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQVIDVEVGNIFDEDK"
     gene            complement(14027..14968)
                     /locus_tag="VUR46_001134"
     CDS             complement(14027..14968)
                     /locus_tag="VUR46_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET5456570.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQVGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(14958..16214)
                     /locus_tag="VUR46_001135"
     CDS             complement(14958..16214)
                     /locus_tag="VUR46_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET5456571.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIKLHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQVSFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(16216..16878)
                     /locus_tag="VUR46_001136"
     CDS             complement(16216..16878)
                     /locus_tag="VUR46_001136"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET5456572.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIAIEDGQNLIAYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(16841..17497)
                     /locus_tag="VUR46_001137"
     CDS             complement(16841..17497)
                     /locus_tag="VUR46_001137"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET5456573.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVANPENHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(17508..18386)
                     /gene="rsgA"
                     /locus_tag="VUR46_001138"
     CDS             complement(17508..18386)
                     /gene="rsgA"
                     /locus_tag="VUR46_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET5456574.1"
                     /translation="MQGQIIKALAGFYYIESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNNLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIIYISKMDLLEDRSELDFYQQTYGDIGYDFVTSKEGLLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(18388..19260)
                     /gene="rsmA"
                     /locus_tag="VUR46_001139"
     CDS             complement(18388..19260)
                     /gene="rsmA"
                     /locus_tag="VUR46_001139"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET5456575.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGTLTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESDIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLT
                     EFASLAAALKGQGL"
     gene            complement(19391..19699)
                     /locus_tag="VUR46_001140"
     CDS             complement(19391..19699)
                     /locus_tag="VUR46_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456576.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLWVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(19692..20333)
                     /locus_tag="VUR46_001141"
     CDS             complement(19692..20333)
                     /locus_tag="VUR46_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456577.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKIIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVEALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVGLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(20335..22365)
                     /locus_tag="VUR46_001142"
     CDS             complement(20335..22365)
                     /locus_tag="VUR46_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET5456578.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWNQFSDRYRLSFGW
                     SSVFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPDSLREQSAYYQGLFTDYL
                     QNFSSESVEVTSRKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLSGMTIYELHGKYLLAQGG
                     VLLLGLILSSVLTGDSLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(22634..23533)
                     /locus_tag="VUR46_001143"
     CDS             complement(22634..23533)
                     /locus_tag="VUR46_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5456579.1"
                     /translation="MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFLFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(23605..24165)
                     /gene="rnmV"
                     /locus_tag="VUR46_001144"
     CDS             complement(23605..24165)
                     /gene="rnmV"
                     /locus_tag="VUR46_001144"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET5456580.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(24165..24938)
                     /locus_tag="VUR46_001145"
     CDS             complement(24165..24938)
                     /locus_tag="VUR46_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET5456581.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQIYATIGWHPTEAGTYTEEVEAYLLDKLKHSKIVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIAYLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(25243..26073)
                     /locus_tag="VUR46_001146"
     CDS             complement(25243..26073)
                     /locus_tag="VUR46_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5456582.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAETIGVQAIAMVTVPKRPVAPNAAPKT
                     TSAPQATAGTMQDVTYQSPAGKQLPNTGSVSSAALASLGLVVATSGFALLGRKTRRRK
                     "
     gene            complement(26357..26491)
                     /gene="rpmH"
                     /locus_tag="VUR46_001147"
     CDS             complement(26357..26491)
                     /gene="rpmH"
                     /locus_tag="VUR46_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET5456583.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(26636..27850)
                     /locus_tag="VUR46_001148"
     CDS             complement(26636..27850)
                     /locus_tag="VUR46_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5456584.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(28006..28299)
                     /locus_tag="VUR46_001149"
     CDS             complement(28006..28299)
                     /locus_tag="VUR46_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456585.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            28462..28914
                     /locus_tag="VUR46_001150"
     CDS             28462..28914
                     /locus_tag="VUR46_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET5456586.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVYSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(28949..30337)
                     /locus_tag="VUR46_001151"
     CDS             complement(28949..30337)
                     /locus_tag="VUR46_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5456587.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            30403..31365
                     /locus_tag="VUR46_001152"
     CDS             30403..31365
                     /locus_tag="VUR46_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET5456588.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKAHLKLLIALNAGLTGQALKDYMEG"
     gene            complement(31706..32716)
                     /gene="ccpA"
                     /locus_tag="VUR46_001153"
     CDS             complement(31706..32716)
                     /gene="ccpA"
                     /locus_tag="VUR46_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET5456589.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(33140..33739)
                     /locus_tag="VUR46_001154"
     CDS             complement(33140..33739)
                     /locus_tag="VUR46_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456590.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEIPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(33740..34837)
                     /locus_tag="VUR46_001155"
     CDS             complement(33740..34837)
                     /locus_tag="VUR46_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5456591.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(34837..35574)
                     /locus_tag="VUR46_001156"
     CDS             complement(34837..35574)
                     /locus_tag="VUR46_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456592.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKINNWQKTLRHSPINMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVEMPLGSWVGAAILLILGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNKGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(35576..36460)
                     /locus_tag="VUR46_001157"
     CDS             complement(35576..36460)
                     /locus_tag="VUR46_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456593.1"
                     /translation="MNMIKVESLNKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQKIY
                     PNHLSNQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVMTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILVLNKGGLIRDTTPLAIRSE
                     EIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWQLLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(36447..36641)
                     /locus_tag="VUR46_001158"
     CDS             complement(36447..36641)
                     /locus_tag="VUR46_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456594.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQAFLHQAIRGAWGLEFM
                     IFIAFPMGKEWLKGEYHEHD"
     gene            complement(36638..36844)
                     /locus_tag="VUR46_001159"
     CDS             complement(36638..36844)
                     /locus_tag="VUR46_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456595.1"
                     /translation="MEEEEMKNKMIVAVSLVTAGVMTYLMFSGLDEGFYHFPWELFAG
                     FGMMSWLIREGLKLVSDVKKEFEK"
BASE COUNT        10836 a         8704 c         6945 g        10941 t
ORIGIN      
        1 ttggcatcac attcgaatca cgctatggta caaaaaactg aaaaaactat tgactgaaaa
       61 tcattttcaa ggtataataa taaacgttaa ggcggtatag ccaagtggta aggcacggct
      121 ctgcaaaagc ttgatcgtcg gttcaaatcc gtctaccgcc ttctataact tgatttatca
      181 ggtttcaaat gaacagaaag cccaatttga agggcttttt ttattttccc tcgaataaat
      241 acgtataact ttaaaaactt ttggagcgag tttgtggcag agttctttcc atggcataat
      301 tcccttttga aatcaattga aaaaagcttc gtcacgcctg gtgacaaaag cctctagttt
      361 attctgtttc ttcttctatt tcgacttctg tgatttggac ttttaccttg gtaacacgtc
      421 cattcttcac tttatcattg gttaagataa actgtttgtt ttggctgacc aattcatagc
      481 tgagtttctc agtcgttgga atggttccca ctcctgtcaa ataataacca gcgatggtat
      541 caacgtcatc actttccagt tcaacatcaa agtaattatt gaaatcattg agggtcatag
      601 ttccttgaac aatgtaggta tcctcgccaa tctgatgaac atctattgct gctttgtccg
      661 tttcatcatc aatttcacca acaatttcct ctaagaggtc ttccaaagtc accaaaccag
      721 ccataccacc gtattcatcc agcaagattg ccatttgtct ttgggtattt cgcagttctt
      781 ttagcaagtc atccacaaaa atagtttcag gtacaaaaag tggatcttgt aaaattctct
      841 tccaaacaat attgtcaaaa ccgtccacaa agcctgcctt aaggagactc ttggtgtgaa
      901 tgattccaat tacattgtcc ttatccccat cataaaccgg gatacgagaa taattttgtt
      961 ttaaaatact ttggataatg gcttgactat catcctgaat atccaccata aaggcatccg
     1021 ttcgaggaac cataacctct cgtgccatca gttcatcgag cgaaaagaca ccttgtagca
     1081 tctcaatctc atcagcatcc aatgtttctt cactatttgt caacatatag gcaatttcat
     1141 cacgggtcat cttttcatcc gcatcatcga atgacatagg agtcaaatgg ctcaagaaat
     1201 tggtcgaagc agctaaaagc caaacaaaag gactgactag ttttccgatc ccaatgataa
     1261 tcggcgctgt acgaattgcc aaggcatcct ttagattaag agcgattctc ttaggatata
     1321 attccccaaa aacgatggaa atataggtca aaaatgccaa ggatagaaaa gttgccacgg
     1381 cttgtgctgt ttcgccattc ccaagccaag aggcaatcac acgtcctaga gtatcagtta
     1441 aactcgcccc tgataagatt gtaatcaggg tgattcctac ctgaatggtt gataaaaagt
     1501 ggttaggatt ttctagtacc ttcagcaggc ggatgtagcg tctgtctcct tcttccgcct
     1561 tttgttcaac tcgggcacga ttaagagaaa ccatggccat ttctgtggct gagaaaaagg
     1621 catttaatac cgtcaagata aacaataaaa caaattgtag caacaaattc tgactacttg
     1681 ggtcttccat agttcttctc ctaaaatagt atcttatcct ttattatatc acaaaattta
     1741 atccaataca tattattttt ttcttagcgt aacttccatc tctctcccaa aactggaagt
     1801 tagtctaaga cggatttcca ctgatttcac gcgtttttct catactaaaa gctaggttgt
     1861 gggaaactgg aagttagttt tagaagttac cattttttct tagtacctat tctagccctg
     1921 cttaaactag taaaaagaac tcctacatcc ataagtgaca taggagttta ggcttatctt
     1981 ttactgagtt acagttactt ctccagttcg gtaatccagt tgaagtccct tttgaacatt
     2041 gggaactaga acattgaatt ccaattctcc atccgaagac ttggcttcaa tctgtgaagc
     2101 tgagggaact aaatcctcgt ttgaagcgta gtaaagggtt acacggtaac ggacacgctt
     2161 gttttggtcc aaggctttac gcaccttgct ttcatagtag ttttgaccag tcgaatcctc
     2221 ggcttgtgcc tgatttgccc aggctgtttg aacagcaatg tttttaggat tgcttgtcga
     2281 ggcatcaaaa ccatccaagc caccgattaa ggcatagcct aacaagtgac ctctatcgac
     2341 cgcatgggta taagtcccct ttagattctt gacctgatgc caacctggag gagtccaaga
     2401 agttgaacca ttcccagttt cttcacgatt cttgtactga cgagtggcct tagacaaaag
     2461 ggcattagct acggttggaa cagtttcctt gcccactgtc tttgttttat tgtcagcgta
     2521 gggcttactt gaaaccttgg catctagatt tgttttatta ccattgacga taaaagcacc
     2581 tgagccattc cactccagac tcccctttat ttgactcttg actgcgtctg ttaagacact
     2641 ttctgccaat tcttgactag gagcttcagg cgcttgtttt ttctgactaa gattggtttt
     2701 gggactatta ggtgccgact gcatctgctt gatataatag ctccctgtag acaaaagcaa
     2761 taacactagc agtccgatta gtgtctgtct tgtttttttg ttcatatttc tccttatctt
     2821 tagaaaaagg ctggttctcc agcctaattt cctgtaaatt tatgaatcaa ttcctgccat
     2881 tttgccggag acaggatagc ccacggatct tgacccttgc ccaagattcc atagcctacc
     2941 attaaaccga ttcctaaggc tagaaggcct aaaatcagta ccagaatgac taaaagtaaa
     3001 cgcttgatta cgtaacctga tttcttattc atcttcatca cttgcctcaa tccgctgaat
     3061 cttagcacct agctgcgcca acttctcatg gaaaccgtag taacctctat ccaagtgaac
     3121 caatttaccg accacagttt ctccctgtgc taccaaacct gtcaaaatca aagctgcact
     3181 ggcacgaagg tcagttgaaa gaacttctgc tccctgcaaa ggctgtccac caacaatacg
     3241 agctgtatca cggataatct cagaatgcaa gcccatgcgg cgcatctctt ctaggtgttg
     3301 gaaacgattt tcgaaaactg tctccaccat ggttgattcg ccttttgcaa ctgtcatcaa
     3361 ggctgtaaat tgagcctgca tatctgttgg aaatcctggg tggggcaagg ttttcacatg
     3421 aacagctttt agattttcta gttgagaacg aacacgaatt ccttcgtctt cttcaattac
     3481 ttcaacaccc atttcaagta acttggcaat caagggacgg ttgtgctccc agacagcgtc
     3541 tcgaatcaag acatcaccac cagtcatggc agcagctacc ataaaggttc ctgcttcgat
     3601 acgatcttgg actacattgt gagtcgtacc atgaagtttc tcaacaccag taatggttat
     3661 agtctctgta ccagcacctt tgaccttggc tcccatttca ttaaggagaa tggctaagtc
     3721 aacaatctca ggctcacgcg cagcattctc aatcactgtc accccatcag ccagagtcgc
     3781 tgccatcatc aagttctgcg ttgcaccaac acttggaaag tccatataga tatgagcgcc
     3841 atgcaagcgt tctgccttgg cttctatgta accagctgtc tgactaatct taacccccat
     3901 agcttccaga cctttcaaat gaagatcaat aggacggcta ccaatcgtac aaccacctgg
     3961 catggatacc ttggcatgac ccacacgggc aaggattggc cctaatacaa cgatggaggc
     4021 gcgcatcttg ctgacatact tgtaaggggc ttcctcagtg atgtcgccag tagcatccac
     4081 cttgacaaga tgagcttcct catcaaagtc aaccttggca ttcaaaccac caactacctg
     4141 attcataata aagacatccg acaaaatcgg aacattctgc aagacggtct ctctttcact
     4201 tgctagaata gtcgctgcca acaagggtaa gactgcattt tttgctccct cgatcgtcac
     4261 gcttcctacc agacgattat cgccaccttg aaccacaatt ttatccatac tcgtttcctt
     4321 tactcttgat tttataataa tcctctaagc gcttcttgcc acaaatgata caggctaata
     4381 aagaaagaac tcaggatgta gcctatgaca atgctaaaaa aggctactaa taaacgaact
     4441 tttcttgtat tatcatctgt cacttttaaa accttctccc atctaacaag atcctttaaa
     4501 aggtaaaaac tcacataaat aaagagcata tgactactta gagtgaataa taattgaacc
     4561 atttgactat tataccatct tctctgtttg tgcgctagtt tggaaacttc actcaaaaat
     4621 tagggattgt ttttcaagta atcaatcgca tcttgtaggg ttttaacggg cacgattttc
     4681 atatccgtct tgattgtttt agccgcttct agggctgttt ggtagttgtt tttcgcgtcc
     4741 ggatgcgcct tttgttcttc ttcgctaaca gggttatcag gagcaaagaa aatagcacca
     4801 cctgccctag ccgaagctac aaccttctta tcaatacctc caatgtctcc cacattacca
     4861 tcgcggtcaa tggtacctgt accggcaaca atacgaccat tacgaagagc tgggtgagct
     4921 atttgagtat agatagctag actaaacatg agaccagcac ttgggccgcc aataccagct
     4981 gttgaaaagc taattgggac attgctgatt acctctgtac gatcaatcaa gccgattcca
     5041 atcccatttt ttccattttc caaggtgata atctttcctt ctgcagactt ggtttgccca
     5101 tcctcttcat aggtgacctt gacggagtcc cctaattttt gagaactgac gtaatcaatc
     5161 aagtctttgg aactatcaaa ggtctgatca ttgactgctg tgaccgtatc agagatattg
     5221 agaatccctt taaaggttga attatccgtc acattcaaga cataaacccc aaagtacttg
     5281 agttcgatat ccttaccagc tgtttttaga ccttgatact tggccatatt ttgtgatgtt
     5341 tgcatgtaga attgattgat tcgcataaat tctacatcgg aagaaccacc tgtggtctcc
     5401 tgaacactac gaatatctgt aaaaggcgtc aaccaagcat aaaccatatg agctaatgtg
     5461 gcatgttgaa caccaaccgt aacgaattga taggcaccag cttccttatc ttctgtgtca
     5521 tttactttaa ggacttggcg aatatcttcc gaaccacctg gaacctctat ataataaggc
     5581 aagggcacta caaatgccaa gaaagtcaca atcaaggccg caatgacgta taagggccat
     5641 ctaatctttt ttttcatttc ttatttcctc caaaatactc tcgggaacat agcaggcaat
     5701 atcctgacca aacttcaaaa gctctctaac gcctgatgaa ctgatataga gatgttcagg
     5761 tcgactatgt aaataaatag tctctatatc agaagacagc tgatgattgt agtaatcaaa
     5821 actggcttca tattgcaaat ccgacgcatt cctcaaacca cgcactagac aagtagcacc
     5881 caatcttttt gcaacatcga ccaccaattc atcatgagaa gccacgactt caacattttc
     5941 caaatgtccc aaagcctttt ctagcccccg tttacgattt tcaagaggga gaaatccttg
     6001 tttgtgggga ttaaaaaaaa tacccacaca aagcttatca aaaagtctgc tcgcccgttc
     6061 aatgatatcc agatgcccat ttgtcatcgg atcaaatgag cctgtgaata agccaatctt
     6121 atctgacata gactgtcacc ttactaattc cataaatctt ttccttccag atacccagac
     6181 aggcaatctc ttctggaagt tcaacggcct tatccgtctc gcacacaacc ataacatctt
     6241 cagaaaaaag ctctctctca gccatttttt caatatctgc tacgatttgt tccttggcat
     6301 agggagggtc taagaaaacg aggtcaaatt ccccagatac ctgttccaat gccctctctg
     6361 catccatctt gaggagttga aattttccaa cttccttggt catctggata ttttcagcca
     6421 cgatggtctg agccttacgg tctcgctcca ccaaaacagc actggacatg ccacgcgata
     6481 ctgcttcgat agataaacca ccactacctg cataaaggtc caagactcgt cccccttcaa
     6541 agtagggacc aatcatgtta aaaatggctc ccctaacctt atccgaagta ggtcttgttg
     6601 tcttgccttc tagtgtcttg aggggacgtc ccccatagat tcctgatacg attttcatac
     6661 tgtttattgt accaaattat agacaaaaag agaaagaaaa ccgaaccttg cggttcgatt
     6721 ctctacaaaa tattttcgta agtatcgcgg acttcttgag gccaaacact tgtttgcact
     6781 tctccgatgt gtctcttgcg aagtaggaac atggccatac gagattgtcc aattcctcca
     6841 ccgattgtca atgggaatag gccattcaac aaagacttgt gccattccaa ttccaagcgg
     6901 tcttcatcac ctgtaatttc cacctggcgt ctaagagttt cttcatctac acgaattccc
     6961 atagaagaca actcaaaggc tccacctaaa gactcattcc agacaagaat atcaccattt
     7021 agacccttgt agccattctc agactcgctt gtccagtcat catagtctgg tgcacgtcca
     7081 tcgtgcggtt taccatctgg caactcgcca ccgataccaa tcaaaaagac ggctccaaat
     7141 tctttacaaa tcgcattttc acgttctttc ggtgtcaagt ctgggtagcg ttctaccaat
     7201 tcttctgtat ggataaaggt gatttgtttt ggcaagatag actcgatgtc atagcgagct
     7261 tcaacagcta gctcagtcag gcgaatagcc ttataaatct tctcaactgt ttcttttaga
     7321 taaacgatgt tacgcttacc atttgggata accttctccc agtcccactg gtcaacataa
     7381 acagagtggg ttgcatccaa ggaatcctca tctggacgaa gggctttcat gtggacaaag
     7441 agaccctctc cttcaccaaa gccaaaacga gccaaggtgt ggcgtttcca tttagcaagt
     7501 gagtgcacca cttcataagt agcatcaggg atttggagaa ccttgaccga tactggattt
     7561 tccacaccag acaggttgtc ctgcattccg tcaccgacct tactcaagat aggaccttga
     7621 acttcgacaa cttctagctt atctttcaaa tactgggtca aagtgttttt gacaaaggaa
     7681 atttcttctt gttgatggat aaaacttttc ttcatagaca actcctcaaa aatttaataa
     7741 acgtattata cacctatttc caagaaaaga aaagagaaaa tttaaaaaaa tcagtgtcac
     7801 tcaaaacact gatttcatag accttttagt cattgcgacc aaagatacgt agaatactta
     7861 ggaaaagatt gataaaatca agatagatgc tgagagccat tgacaccacc cagcctgtcg
     7921 ctacacgacc ttgtgattgt tcataggcga ggcgaatctt ttggttatcc caagcaatca
     7981 accctgaaaa aaccaaaacc atggctacgc taatcatata atcaaagaag ccactagcaa
     8041 agaaaatatt gactaccata gcaatcagta aaccaatgag agctgccatc attgctcgac
     8101 caatcccact caagtctttc ttggtaaaga taccaactgc cgccatgaca aagaagagaa
     8161 gggcgctcga tacaaaggca gataaaactg tacccggagt atagaaagcc accacaaaac
     8221 taagggtaaa gccgtttaaa acggagtaaa gtaaaaatac tggaagagca gctggactat
     8281 ttcttgaagc catgctactg gcaacgaaaa ccaaagccaa ctccgcaaaa gtagcaatgg
     8341 tcaaccagag acgcccctgc atcaaaaagt aaaccaactg agactgaaag accgtcaaca
     8401 taaggcctga taccaaagca gatagtccga ttcccagacc aacaaaggca taaaccttag
     8461 cgtaaaattg attgagacct gcacggtcat gtataatagt gtgattcatc catttctcct
     8521 tttctgtgaa catctttcct tgattataac aaaaaaagtt aaaattagct taaatggaag
     8581 attaaaatac cggctgcaac cgcaacattc aaactctcgg cctgcccctt catgctaata
     8641 tggaccaact ggtctgcact ttcagccata aggggactaa ttccttgacc ctcatttccc
     8701 ataactagta caaaattttc tatagaaggc agttctctgt aatcaacaga atctttagat
     8761 agggttgttg ctagcactgg gatagctacc tttttagttt cgtcaagaag cgcttgacta
     8821 gtcatccggt aaatgggcag atggaaatga ctaccttgca tggaacgtag ggttttgaga
     8881 ctgtagatgt ctgccgactt atctgaaaca atcactcctg taaaacctgc tgcatccgca
     8941 gttcgaatga tagttcctac attaccagga tcttgcacat cttccaaaaa caagaacttg
     9001 ccctgactca aatcagcttg tcctacttct tctctttgaa ccacggcaac aattccctgt
     9061 ggagtctgag aatccgccaa atctagcaaa atatcctctg acacccagac agtttgcgaa
     9121 aaagtagcta actgatctcg ataattttct agggtaaaga ttttctcaat cgtcactcca
     9181 gcttgaacag cttcttcaaa caagtgccag ccttcaatta aataggcaga cttgcggtat
     9241 tttttttggt gtaatttctt ggtatttttt acaacagaat tggcttttga ggttataata
     9301 gtcatagaaa tattataaca caatcaaagg ggtttggtat gcaaaaggtt agaatgattg
     9361 cccaaggtag ggtgcaggga gtcggctttc gttggggtgt ttatagcctg gcccttgaaa
     9421 tcggtggcat cacaggtcgg gtatggaata acgacgatgg cacagtggaa atcttagccc
     9481 aagcagactc atctgctatc atggcaaaat ttatccaaga aatccgaaaa ggaccgacac
     9541 ctttttcaaa agtcagttac ttagatgtca aactgagcaa ctttcctccc taccctgact
     9601 ttaaaatcgc aaattaggtc tccagaacta ttgtatattt tgtaaaaaaa cagtagaata
     9661 gaaaggtata atttttaaag aaggaataaa aacagtgaaa tctattaaac gttttgcatt
     9721 ctcggctatg ggagtggcta tgttgcttgt cttgactggc tgtgtcaatg tcgataaaac
     9781 cacaggtcag ccaacaggat ttatttggaa tacgatcgga gcgcctatgg ctgaagccat
     9841 caagtacttc gctactgata aaggtctagg ctttggtgtc gctatcatta tcgtaaccat
     9901 tatcgtacgc ttgattatct taccacttgg tatctaccaa tcatggaagg caacgcttca
     9961 ctctgaaaag atgaacgctc tcaagcatgt ccttgagcca caccaaacac gtctcaaaga
    10021 agcaactact caagaagaaa aactcgaagc ccaacaagcc ctctttgccg ctcaaaaaga
    10081 gcacggcatc agcatgtttg gtggtgtagg atgtttccct atcctccttc aaatgccttt
    10141 cttctctgct atctactttg cttcccaaca tactgaaggg gttgctcaag caagctacct
    10201 aggcattcct ctaggttctc caagtatgat tttggttgcc tgtgctggtg tcctttacta
    10261 tcttcaatcg ctcctttcac ttcacggagt agaagatgaa atgcaaagag aacaaatcaa
    10321 gaaaatgatt tacatgagcc cactcatgat cgtcgtcttc tccctcttct caccagctag
    10381 tgtcacactt tactgggttg tcggtggttt catgatgatt ctccaacagt ttatcatcaa
    10441 ctatatcgtt cgtccaaaac ttcgcaaaaa agtccgtgaa gaactagcca agaacccacc
    10501 aaaagcaagt gctttctcta aaccaagtgg acgaaaagac gttacccctg aacaaccaac
    10561 tgctatcaca agcaagaaaa aacacaaaaa tcgcaacgct ggaaaacaac gttcgagata
    10621 agaagaaaaa ggcttagctg atttgctaag tctttttgca aatcaaaagc ccgatgtttc
    10681 catcaggctt cttttctatc catgtacacg tttcatataa tcttgataac tttcggtatc
    10741 catgagtttt ttagcgttct tgacgcgatc tgctgttggt ggtttgactc cttcgaggga
    10801 atatggaatt ccaagttcac gccacttgaa ctcacccatg gtgtgataag gtagaatttc
    10861 aaacttatca acatttttga gggtcttgac gaacttacca agttcaatca agtcatcatc
    10921 tctgtctgtc aatcctggaa ctagcacatg gcgaatccag acaggttttc caatatctga
    10981 tagatactgg gcacaagcca agatattttt attggtttgg ctagtgacaa tcttgtgctg
    11041 ttcttcgttg atttccttga tatccaaaag aaccaagtca gtgacagcca tgagtttgtc
    11101 aaacttctca aggtaacgtg gtttattacg gaaaggaaga gcacaggtgt ccaaggtaca
    11161 gtggattcct tgttccttag ccttggtgaa gagggcaatc aggaaatcaa tctgcaagag
    11221 agcttctcct ccactgactg taatcccacc cttatttccc cagaaaccac ggtagcgcaa
    11281 ggcctctgtc aagacatcat ctaccgtccg ttcacgtgac ttattggact ccatagccca
    11341 agtgtctggg ttgtggcaat actggcaacg catgtgacag ccctgcaaaa aaacaataaa
    11401 gcgaatacca ggcccatcta ctgacccaaa gctttctgtc gaatgcacca ttcctgtcac
    11461 ttgtccataa tcaattgttt cttcagacat atcgttacct tccttgaaaa cgttttatag
    11521 ttttattata tcacgacttg aaggaaaaac aaggtttttg cctatttttt agaaagcaat
    11581 ctgtttttca atttcatttt caattacttc tcagattctt cttcaaaatc aaagccatac
    11641 aaggttgcaa agtagtcctt aggacgctct gcacggcgga tttgacggac tttgccttct
    11701 tcagtataga ggatttccgc agaacgaagt ttggcattgt actggtaacc cattgaaaat
    11761 ccatgggcac ctgtatcatg aatgaccagc aaatcaccga tttctgtatg aggcagttcg
    11821 cgattcactg caaatttatc attgttttca cagagtgaac cgaccacatc taccacttca
    11881 gctggtccat ctggatgtgt cagattggta atatgatggt aggctccata catggctgga
    11941 cgcataaggt tgattgctga tgcatccaca cctagatagg tacggtaggt tttcttctta
    12001 tgagtgactc ttgtgaccaa agctccgtga ggtgccagca taaaacgacc caactcagta
    12061 aaaatcttaa cctgaccaag acctgctggc gtaaggacct cttcatacac cttacgaact
    12121 ccctcaccaa tcaaggcaat atcgttcggc tcctggtctg gacgataatt aacaccaata
    12181 ccgccagaaa gattgataaa gtctaacgaa atgcccaact tttccttgat ttcaacagcc
    12241 agttcaaaga gctgacgagc caactctgga taatagagat gggtcacggt attggacgct
    12301 aggaaggagt gaagcccaaa agtcttggct cctttttcct tcaagatagc aaaggcttca
    12361 aagagctggt ccttggtcat gccaaactta gcctccccag gattgtccat aatgtctgtc
    12421 cccagttcaa aaacgcctcc aggattataa cgacaagaga tgatttctgg aatgcctgct
    12481 gctctctcca gatgttcaat atcttcaaag gcatccaagt taatggtcgc acccaattca
    12541 cgtgtatagg cgtattcctt gtctggcgtg ttgttggaag agaacataat ctcagaaccc
    12601 agaaagtcca gtttatggct catcaaaagc tctacataac tagagcagtc cacaccacaa
    12661 ccttcttctt ggagaatttt caaaatagct ggagttggag tagccttaac tgcaaaatat
    12721 tccttaaagc ccttgttcca cgaaaaggct tggttgacgg ctcttgcctt ctcacgaatc
    12781 cccttctcat catacaagtg aaagggagtc gggaactcgg caacaatcgc ttctaactct
    12841 tctctattaa taaatggtgt tttcataagc ttccttctat tctgtttgca aagaaaggct
    12901 gggacaatcg ttccaacctt tagttctatc tcttatttat cttcgtcaaa gatattgcca
    12961 acctcaacat cgatgacttg gttcttgaca tcaatattgg ttaccttcaa gagtgacttg
    13021 tagtcaaact gcttttcacg ttcttcttgg gcattgtccg caaagaccgc tacacctgcc
    13081 agttctgagt cgaactcgcg caagagacta atcatcccgt tgacagttcc gccacctttc
    13141 aagaagtcat ccacaatcaa gacacggctg cctgccttga gactgcgttt tgaaaggaac
    13201 attttctcga tacggtcacc acttgaacct gaaacatagt tgacgctaac agttgaacct
    13261 tcggtaattt tcaggtcacg gcgcacaatg acaaaagaga cattgaggac attggcaact
    13321 gcatttgcaa gtggcacacc cttagttgct acggtcataa ccgcgtcaat tttttggtcc
    13381 ataaagcttt tggcaataat acgaccaata tttttcaaga tggctggtgt gctaagcaaa
    13441 tcagacagat agatataacc acctggcaag atacggtcac tttctgacaa cttggtacgc
    13501 aagtcttcaa ccatttcctt agcatcctga ctcgaaatag acggtgtgaa gatgacacct
    13561 ccgccagccc cagtcactgt ctggatatga ccgatttcaa tttcctcaaa ggcgcgtttg
    13621 ataatgacga tatcttctga gatggatgat ttagcagact catacttttc agcaaaagta
    13681 ttgagactag ttagtttata aggattatta atcaaatagt tggaaatgac aaccatccga
    13741 tcacttcttc ttaatttcat ttctatttcc tattccattt ttattcaaaa aatcaaaaag
    13801 caaactagaa agctggtcgc tggtggttca aaacactgct ttgagattgt cgatagaact
    13861 gacaaaccct gtaatatacc tgcatatata catacgacaa ggcgatacta ccctagtttg
    13921 aagagatttt cgaagagtat tcatttttgt cttttactta ttataccata ttcacataaa
    13981 aaaacgaaca ttcttatcct aaaaaatgct catttttctt aaattatcaa tctaaatctg
    14041 gtttatagaa ggaacgatta tccatagcga agattttatt ggtcatctct cctttatcca
    14101 ccaaagccag agctgttgac atcatcatca tgcttgcatc cagattgtca atcatatgga
    14161 taatctctgc ctccataata cgtggacgga ctggacttcc atattcaagc aagccgtggt
    14221 gactgaggat gacatgacga agcaaaacga cttcttcctt ggtatcatcg atgccgagtt
    14281 ccataactgt cttggtaatt tcgctatcaa tgagagcgat atgtccaaga agattacctc
    14341 gcactgtgta ctctgtctgg tctggccccg tcaactcgat gaccttagcc aagtcatgca
    14401 acataatccc cgcatagagc aggctcttat tgagctgagg ataaacttcg ctaatagcgt
    14461 ctgccaaacg caccatggtc gccgtatgat aggccaagcc cgtttcaaag gcatggtggt
    14521 tggtcttggc agctggatag gagtagaatt ccttatcata cttggtgtag agatttcgga
    14581 caatccgttg ccagacagga ttttcaattt tgaaaatcat ttgcgacatg tagtcacgaa
    14641 tttccttgac atcaactggt gacttgacct tgaaatcggc tgggtcattg ggttcaccaa
    14701 cttgaggcag gcggagagta atttgattga cttgaggggt attgttataa acttctcggc
    14761 gtcctttcat gtggacaacc ttacctgcgg taaaggcctc aatgttatga ggttgggcat
    14821 cccagagctt cccatcaatc tcgccactat catcttggaa ggtaaaggct aggtagtttt
    14881 tcccagctcg agtttgcctc aggtcagctg atttgattag gtaaaagcct tcaaataact
    14941 catctttttt catgtgacta atcttcatat tcttcctcat tttcttgaaa atggagtaga
    15001 tcaagcgcag gctcaccttc tgacaactca atgtgacgga gcgtccgctc gatagctatg
    15061 gtacgacggt ttaataattc atcaatattg ccagaggcat gttggagatg tttttgcgcc
    15121 ttgaccagaa taccaccaaa cttgccaaac tcggtcttga cactggcaag agtcttgctg
    15181 atatggtcgg cactcttttg gatattaagg gtcttgaaac caactgatag ggagttaaga
    15241 agggctgata gggtacttgg tcctgcaaca ataatctgtt cttcccgtct caaatcatca
    15301 aagaagaccg gattgcggac gatttctgag tagagacctt ctgtcggaac aaacaaaact
    15361 ccaaaattgg tcgtccgagg tggtgctatg tacttgttcc taatatccct agcaaaacgc
    15421 ttgacacttg ctaggagtga cttacgacag cgttcgattt catccttgtc acctacttca
    15481 taggcttctt ctaagcggta ataatctgcc agtggaaact tagagtcaat tggtaggtag
    15541 acgtattctt ggtcgccttg tccgggtaac ttgatggcat actccactcg ttcactagag
    15601 ttttcaaccg ttgcgtattc tcgttcgtac tgggcaggtg tcatgatgtc ttcaataatt
    15661 tgccccagtt gcaattctcc cagaatccct cgcgtcttgg ttccagagag aaccttgtta
    15721 agagctccga catcacgggc aactgtctgc atttctccaa ggccacgatt gacagactcc
    15781 agttgtttag aaactgtctc aaaggaaacc tgtaagcgtg tctgcaaggt cttttctagt
    15841 ttttcctcga ccgtctggcg catttgttcc aaacgttgct catttgattc ctgcaaggct
    15901 tggagacgtt ggtctgtctt gtctctagtt tggaggagat tatctgtcat ttcttgacgg
    15961 acttgggtca gaccttgatg caatttaatc cgcacttctt gcaaacggtc gctgacagcc
    16021 acttccaaat ctttttggtc taactggctg gcttgtctgg cttggtcaaa gcggtaatcc
    16081 aactggtctg acaaatgatc tgcctgatcc tccaagctct tacttaagtg tttctcctgc
    16141 ctatcctgcc tttgccaaat cagaaagaga ccagctaggt tggcaattaa taatagaata
    16201 agtaaacttt ccatcctacc tcctgtcctt gctatgcagt acgaccacat aaccatctgg
    16261 gcaagttacc gacacttccc tatctatata ttcgttagaa gcgtacactt ttttaaagaa
    16321 aaaattttcc tctgtcaact catacttggc tccaagaata gtcagctggc tatcccgaac
    16381 tggcataaag gctagatagt cgtagtctga acgaggttct agctgactgg tcccttctgg
    16441 acaataggca atcaagtttt gcccatcctc aatcgctatc tggcgcatat agggtgccaa
    16501 cttaggattg ctaggtagaa agacattggc caacatatgg tcaatacggc cacccaaggc
    16561 accgaaaata gtgacctgag cctgaggatt ttgttcaaag atggttaaga gagccaattc
    16621 cagatctgta tcatcctttt ctggtcgtgc ttggacaaaa tactgggcac gtttttgaat
    16681 cacctgtcgc tcttcttccg tcacagaatc aaaatctccg actgctagag caagaggtaa
    16741 gtcttcttcc aatacccaga gcgagcctcg atccacccca acaaaagcat caaaatctgt
    16801 ccgataatga ccgcggtttc cgcctgcaaa aactgcaacc ctagtccagt tgttttctga
    16861 gagtttgtac tcgctcattg acttctccct taaagacata ggaacctgct acaaaaacag
    16921 tcgcaccagc ttctttggct tgagcaatag tttggtcatc aatcccacca tccacttcga
    16981 tttcaaagtt caaacctttt tcctcacgaa gagcaaccaa ctcacgaacc ttatccatgg
    17041 tttctggcag aaaggcttgc ccaccaaaac ctggattaac cgtcatgact aaaacttggt
    17101 caactagatg aaggacgtgc ttgatggctt caactggtgt gccaggattg ataacgactg
    17161 aaggcttaac tccgagtgaa cgaatttttt ggagggcgcc atgaatatga ggtgttgctt
    17221 ctacatggat actgatgatg tctgcacctg cacgcgcaaa gtcttccaga tgattctctg
    17281 gattagctac catcaagtgg cagtcaaaga ccatcttgct atgaggtcga agactctcga
    17341 ccacacctgc accaaaactg atttgcggta caaaatgact gtccatgata tcgatatggg
    17401 catattctgc cccagttgct tctaggcgtt tgatttcacg ttcaaagttg gcataatctg
    17461 ctgctagaat tgacggagca atcttgtatt gagacatagg tttctcctta ttttggaatt
    17521 tttttgctga cttttttata ggtttctctg cgattttcaa tttcgctgag gaattgcagg
    17581 tagttgtcaa aacggaaggg cgcaatggta ccttcttcaa ctgctggctt gacagcacag
    17641 gacggctcat gggtatgggt acaagtacgg aacttacagt ctcgactgac agtagcaatc
    17701 tctggaaagg cctgattgag gtcttcagcc gttgacactt cataatccag tgatgaaaag
    17761 cctggtgtgt ctgcgatttt acccccattg aggttgtaaa aactaactgc tcgagtggta
    17821 tggcgcccgc gacccagact gtctgagatt tctcccgttt caagattaag gtctggtgcg
    17881 attttattga gaagggttga ttttccaaca cctgtctgcc ccataaagac tgtaaccttg
    17941 cctgttaaca aaggaaggag tccctcttta ctggtcacaa agtcatagcc aatgtcacca
    18001 taggtctgct ggtaaaaatc caattctgac cgatcttcca gcaaatccat tttagaaata
    18061 taaatgatag gatggatgcc cttatgctcc aaaagaacca agaaacgatc cagcaaattg
    18121 ctgttaaaat caggttcctt gacagacatg atcaccacag cttggtcaat attgacaata
    18181 ggcggacgga ccagattgtt tttccgttca tgaatcttga ggatatagcc ttctgaattt
    18241 tcctcggcag agaaatctac ccagtcccca acgtaaggag tatggccttt tttacggaaa
    18301 ttcccacgcg cgcgtgtttg atagacctgg ccatcactct ctatatagta gaagcctgcc
    18361 aaggccttaa taatttgtcc ctgcatctta gagcccttgc cctttaagcg cggctgctag
    18421 actggcaaat tctgtcaagc tgagtgcttc tccacgcaca cttggtgaca agcctgcttg
    18481 gtccaaggcc ttagtcagct tgtccttgac ttcttcagtc ttgccaaagt aacctgtcag
    18541 gttattccat aaggtcttgc ggcgatgagt gaaactagcc ttggaaacct taaagaagaa
    18601 gttctcgtct tccactgcta cagctggctc tggacgacgc accattttca agatggctga
    18661 atccacattt ggcgctggca caaagaccgt acgaggcacg ataaaggcaa ccttggctgt
    18721 catgtaatac tgcacggcga tagacaagct accgtaagcc ttggtgttag gctgggctga
    18781 aatgcggtcc gctacttctt tctgcatcat gaccacaaac tcacaaaaag gaatgtcact
    18841 ctcaatcaag tgcatgagaa taggcgtcgt gatgtagtaa ggcaaattag ccactacctt
    18901 gattggcagg tcaggatttt taaaattctg gatatgttgc gccaaatcaa ccttgagaat
    18961 atcttcgtta actacggtca cattatcaaa atcacgcagg gtatctgcca aaattggcac
    19021 caaacggtgg tcaatctcaa aagccatgac ttgggctgca cgctcagcca aaaattctgt
    19081 caaggtacca atacctggcc cgatttcgat gacattgacc tgatcatcaa tttcagccgt
    19141 atccacaatt ttttgaagga tattggtatc cgtcaaaaaa ttttgcccaa aggacttttt
    19201 aaaggtaaaa ccgtgacgct ccagcactgc cttggtcacg ctataatctg caattctcat
    19261 ctattctctt ttctattatc tgttactact attgtaacac attccccttg tattttggga
    19321 atgaaaatca taccaaaaaa ctatctttcc tcatgaagaa agatagtctt ggaaatcttt
    19381 aaaagtggcc ttagcagttc tctcgaaaca tgcgttcaaa aaaatcagct tcttgataac
    19441 ttcgattttc gggtagggtc aaatccacat cctcctccac atcatccact gtcagttcaa
    19501 ccgtctgagg taaatttttc aaacgataat gcttttgcct ttgcccttca atactagcaa
    19561 aatcaagcaa atagccatgc actcggattt gaacccaaag gagatgattg gtcatatttt
    19621 ccatgatgag gatatcttct aaaccacctc tggcactagg ataatcagat accctgcgaa
    19681 tacggatttt ttcacacatg agcaagtttc ctcatatcaa tgatttcatc agccttattc
    19741 cagactaggg gattatgggt cgcaatgatg atcattcgat tttcatcttt caagcccacc
    19801 aagagattca taacctcctc tgaattttca ggatcaagag ctgctgttgg ttcatctgcc
    19861 aaaatcaagg gtggattttt caaaatagtc ttagcaaggg caactcgttg ggcctctccc
    19921 ccagataaag tataaatttt ttgttctaga tccaaatacc ctagattaac tttttctaaa
    19981 gcctccactt gcctttccaa acgttctact tttgaaatct tttgaccaac aaagcccaaa
    20041 tccaaatttt ctttgattga ttggttttct aaaaggccaa aattttgaaa gagatagccc
    20101 atctgatctc gaaaatactc acgagtggga atgattttta aatctttccc ctgatagaga
    20161 acccttcctc catctatctt ctctagcttt cccaagatat tcagcagcgt cgtctttccg
    20221 cttccactct tcccgattaa ggcatagacc ttgcccttct ccagtttgag attcaaacca
    20281 gagaaaatcg ctcggtcatt aaatttcttt tccaatcctt gaatatcaat catcttattt
    20341 tcctttcaat actgccatgc taccagcttc ttccttttta tcctgcctta ctaaaatcaa
    20401 gagggcgtta agagtaaata aagctacaac taaagcgctg atcaagctat ctcctgtcaa
    20461 aacactagat agaattaggc caagcaagag aactcctcct tgcgccagta agtacttgcc
    20521 atgaagctca taaattgtca taccagaaag acgtttaatc ataagctccc gtctaaactg
    20581 ctcaaaatag agaagattca tggaatcaaa taacaagata gccgtagaca gggtcaaaat
    20641 cgtcccaata aggagagagt aaaactccac ccgtttgtca tttagtacct tggcaaaaaa
    20701 tagctggctt tttaccaagt aagaaacctt gtgatacaga ccttgctctt ttagagctgt
    20761 gatgctgtct ccatatcgat ctagtttcaa ggcactatta gccgtagttc cccacaacat
    20821 ccctgcaaca ggtcttgttc cagtcgcttg cggcgttaga actacaataa tcggatcttt
    20881 taggtactgg cgtgttgtct tgtacccatc attatagagg aaacgttcct gtcctgtttc
    20941 tgtaaaagct agccttacct gtgggaagta gtgtttccga ctcgtcactt ctacactttc
    21001 agatgaaaag ttttgcaggt aatctgtaaa caatccttgg tagtaggcag actgctctcg
    21061 caagctatca ggcaagatca gcccaaactc tccctcagac aagttttgca tcttgtccat
    21121 aaactctgaa gaaacggtaa tcttttcttc tatcagatag cgtggtgaga catagataac
    21181 attccctgac ggtgtgtagt cactgagacg attgccatct aggtccactt ctgctccatc
    21241 tgagaaattg tcaacattgc tcataatata aaaagagtct gtattggcta accgttcttc
    21301 agtaaatgtc tgccactcac gattatcctt acgcgttcct tcttcatcgg caaatacact
    21361 agaccaacca aaggatagac ggtaacggtc tgagaactgg ttccatttat tgctagctct
    21421 ctccatttcc tgcatttcac ggtagtgggg taggagagct gtcgcactcg atccgaccac
    21481 caatacagct aagagttgcc ccaccatcat caatgtcatc atacgtttga gagggagttt
    21541 ccctttcaat agatccacca gactattttc ctgtaaacca agtagataga cgacacttag
    21601 taaggtagaa atccctgcca aggtcaatcc ataaagtaga agagcaatga tgaccagttg
    21661 caccgttgcc ataaacaagg caccttgata ccagagaatc cccaatccca aaagactgga
    21721 taccagcact gagcagataa gctgtctcac atcttctaac actggtctga gagcaactcc
    21781 aaacaagctc tcaccagcta ttaagcgaat ccctgcctga cgaagggatt tgatccgata
    21841 aataagggtc agactcataa aggtcagcag aaaaatagct aaactcagta gcaccatagg
    21901 ggtggccgcc aatagtaaga ctatcgaaaa tggatcttct ccattcgaaa caaagccttg
    21961 ataaccaagc tctttcaagg tggtctgtaa gctcactcca tccaaacttc ctgatacaat
    22021 caagtaagac cctaataaat cactcgtttc tgcactctcc ttggaggaaa tggtcagacc
    22081 ttctggaagc tttccctcac cataagtggc ataggtaaag cgtgtttctc cagcttcatt
    22141 tggctcaaca atccgacggg cgatgagact attatgctct accgccaagt gactcaaagc
    22201 ctctgtcacc tcttcgcgac tagctactgg ttgatttatc atcattcctg tcacatcaac
    22261 agaaggatag ttaccaaata aaatctcttc tcgatggtca acggaagtta tcaccatata
    22321 aagcgatacc aataccattg aaatcaaaat aaataaacgt ttcatcattt cctccaaaaa
    22381 gttacttggt cacttagtga gaaggtgacc acagtcactg ccatgttaag aagtttatta
    22441 agttttttct actagcaaca tcttcaaata tattatatcc gttttttcaa gaactatcaa
    22501 gggcatcaat gtccttaaaa tctaaccatt tcgtgtcatt tttagcttat atctaaaaaa
    22561 acagccctaa agacgaactt tagaactgtt ttgatgcgag aacaaggaca tttttgtcac
    22621 tgattcacta tgtttataaa tattttttga catcctcttg ccattcctct gtcaatttct
    22681 ttactagaaa ttcatctcca attagctgcg caaatgtttt agaagactga taaaatgatt
    22741 cagctaaact aaaatctctt tcttctctta atgcttgctt ccacaaaaac agaaatacaa
    22801 gaggtttctt ttgataatct tgagttttat ccataatttc ttgtaaacac gatagataat
    22861 cattaaaaca atcagttact cctacctttt caagacaaca cattcctgaa ataagagtat
    22921 ctctaattat aaagaagttt tctaatttag ttaccttttt ctgttccaaa agaaagagca
    22981 ttagcttttc gatttgattt ataaatttgg caagatcttt tctaatgagc atttgataaa
    23041 aaaacaaacg aatcaacaac atatcatttg ttgaataaac ttctttttct atgatctgag
    23101 gcatatgttc ctcaagtatt aactctgcat attcaggcct tctagttcta gaagtatcca
    23161 aacacgcctg caatacttca cacgctaatt gttcttcttt aggaagatta tcaaagtatg
    23221 ttttataaat ctcttccaaa cacgcttcct tcttatcgta ctcctcttct ttaccataga
    23281 ttggttcacg taaaatctgg tatttcaatt ctaaataagc agaaggaaga gctgaaaaat
    23341 ccggcataag gctataaact ggaactccta gccggcgagc aatatagtct aacttgggca
    23401 aactcggttg cgaagctcca ctttcaattc gcgacagttg acgaactgtc agttcttgct
    23461 catctccaca aaaatctgga cgactaactc ctttttctat ccgaatctct ttaatttttt
    23521 gaccaattaa catcagacgc ctcctcttct acctgcttcg aaaaatactg tgaaacttaa
    23581 aaaattgtaa cggctacatc tttcctactc ataagatttc atagcttctt ccacttctgc
    23641 caaagtaacc ccaaacaact ctaggcgttt gaggagttgc ttgccgttag aatagccgat
    23701 tcggagagtc tctccgagat attctctacg cttacggctg tctgcccctg ctagaaaacc
    23761 aaggcgaatc aaatcgctac gactaatgtc aaactgactc tcatgttcaa attgttctgt
    23821 cacctgagct agagccgttt tcaggtcttc atagctggca tgctcaattc ccagagaacg
    23881 ccccttggtc ttggacttgg gaacagcttc atctcgcttg agaaaggcat gctgaactgt
    23941 tggaatggcc gtcataatca tgcgccgaat ccgctcccca ttaaaatctg ggtctgtaaa
    24001 gacaatgact ccatgacgtt ggtgtagacg ctgaattcgc tctatatcct gatcattgat
    24061 ggcagaacct cgtgtctcat aggtctccac atcgaaataa cgcttgagat tgaccgtatc
    24121 atcgcgacct tcaaccacga taacttgaga aattttctct ttcattactt gctgtccaat
    24181 ccaaaaattc gttctgcatt tgcagtcgtt gctaccgcca gctcttctgt cgtcatacca
    24241 cgcaagtaag cgataaagtc gaccacatag cgagtatagg ctgttttatt ttcacgacca
    24301 cgcttgggta caggtgctaa gtaaggcgca tctgtttcca ccaacatctt gtccaaaggt
    24361 aactctttag ctgcttcttg gaggtcagtt gccttcttga aagtcaccac tcctgagaag
    24421 gaaatggtca taccaagatc cacaaacttc tctgcccact caagcgtccc tgaaaatgaa
    24481 tgcatgatac caccacgagg accaacgccc tcactcttga taatctcata ggtatcttcc
    24541 agcgcatcac gggtatggac aacaaaaggc aaatccaagt ccttagatag ctgaatctga
    24601 cggcgaaaaa cctgctcctg cacctctttg ggcgctgtca tccaatggta gtctaagcca
    24661 atttcaccta aagccacaat cttggaatgt tttaacttat ccaacaagta agcctcaact
    24721 tcctctgtat aagtaccagc ttctgtagga tgccaaccaa tagtcgcata gatctgctca
    24781 tactcatcta ccaactccaa ggcatgctca atcgtcggtt tatcaaaacc aacaatattc
    24841 atctgtgtca cacccatctc agcagccaag gcaatttctt ctgcctcacg acctgcaaat
    24901 tcttctacat tcaagtgtgt atgtgtatca aaaatcatct cttctaacct cgttttctat
    24961 cttctattat accaaaaaag aggaggggca cctaattttt cggtttcccc tcctctcttc
    25021 aataaagagc tattctgcta tcttttctat ccgatattgc ccatctccta ttccacagtt
    25081 agagacagaa gagattggct acattgatag aatattccta ttcagctaaa gtatatgatt
    25141 atcttgggtt ctcacttttc tcacccatca ctaggattga tgacttctca aaatccccct
    25201 tataatttaa ctttaagtag agaatagaat tttctagctg ttctattttc tacgtctagt
    25261 ctttcttcct agcaaagcaa aaccacttgt tgccaccact agaccaagac tagcaagtgc
    25321 tgcacttgat actgaacctg tgttaggtaa ttgtttgcca gcaggtgact ggtaggtaac
    25381 atcttgcatt gttcctgcag ttgcttgcgg tgcacttgtt gtcttaggag cagcattagg
    25441 agccactggt ctcttaggaa ctgtaaccat ggcaatggct tgcactccaa tcgtttctgc
    25501 ttccactctt gctaaaagtt ctgctttttc tttatcagaa agcggtgcgc ctttgatttc
    25561 atcctgcttg ttcttggctg ctttttcaat ggcattttta gctgattctt tttcagtagc
    25621 taattgctta gaagcttgtg attgagctga gttttgtgaa cctgtgtgag ctgatccacc
    25681 cgcctggcta ccaccgcctt cattcgcatt agcatctgag cttccagtat tgcctccctt
    25741 atctccacct ggtgtagttt ctagcttata ctctggtgta gcttcttgag ttacagattc
    25801 acctttcgca gattgttgaa ctgtatcttt tcctagaatc gtcactactg aaccatctgg
    25861 gaatgtgatt gttgctgtac catctccagc tacattgatt gtagctccgt ctaatgctga
    25921 accatttgct tgtaaaatag caaccttaac tttttcttca tctgttaaat gagttatatc
    25981 ttttacatct actctttgag caggtgcttt aacagttgat ttttcagcag tcggtttagt
    26041 actatcttgt gcttttggat cttgtgctac caattgattt cctggaattg taatagctga
    26101 accatcttta aagacgattg tcgctgtgcc atctccagct acttcaactt tatagtaaaa
    26161 taaaataata acaggacaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
    26221 aaacagaggt gtactattct agtttcaatc tactataaca tcgcttccga atccatttgc
    26281 atctactgaa cttttttaca aaaataaaaa tcagtagact cgagttccta ctgatttttg
    26341 atagaattcg tttggattat gcagccaaaa ctttgcgtcc tttacgacga cgagctgcca
    26401 atacgcgacg accattttta gttgacatac ggttacggaa tccgtgtttg cgcgcacgac
    26461 gaagtttact tggttgataa gtacgtttca cgatgaatac ctcctcatag attttgtatt
    26521 cgtttagccg gctataaagt gatcagttac taaacatact ttactattct atctgattct
    26581 ttcacttttg tcaatagctc taggcaaatg tttccagctt tttcgaatgc aagccctatc
    26641 tacgatactg tttcaagaaa cgagtcatct tttcttggat ttgggctaac tcatcaacac
    26701 gaggaaggta aacgatacgg aagtggtctg gttcctgcca gttaaagcct cgaccatgaa
    26761 ccaagagaac cttttcctgc ttcaagaaat caaggacaaa ctgctcatca tcatcgatac
    26821 ggtacatatt gcggtcgatt tttgggaaga tatagagccc cgccttgggt ttaacggcag
    26881 acaaacctgg aatatcttga atggcattat agatgaaatt tctttgctcg tagattcgtc
    26941 caccaggaag aagcaattca tcgactgatt ggtgaccccc caaggaagtt tgtacgactt
    27001 gttgggccaa aacgttagag caaaggcgca tattggacag catattgagc ccttcgatat
    27061 agcccttaac atgagtctta gggccagaca agaccatcca acccacacgg aaacctgcta
    27121 tgcggtggga ttttgacaga ccattcatgc tgacacagaa gacatctggt gccaagctcg
    27181 ccacaggcgt atgcacatgt ccgtccatta ccatgcggtc atagatttca tccgcaaaga
    27241 taatcaaatc gttttgacgg gcaatctcaa taatctccag caagagttcc ttaggataaa
    27301 gggctccagt tgggttattt ggattgataa ggacgattgc cttggtattg gaagtgattt
    27361 ttgacttgat atcgtcaata tctgggtacc attcaacagc ttcatcacag atatagtgaa
    27421 cggcatttcc tccagctagg ctgacagccg ccgtccatag aggatagtct ggcattggca
    27481 ctaagacctc atccccattg tccaaaagcc cctgcatgga catgacaatc aactcactga
    27541 caccatttcc aaggtaaata tcatcaatat ctacgtttgg gaatttcttc agctggcaat
    27601 actgcatgat ggccttacgg gctgagaaaa tccctttgga gtcagaatag ccttcactat
    27661 cacgcgcatt cataatcaag tcatgaatga cctcgtctgg cgctgtaaag ccaaattctg
    27721 ctggatttcc tgtattcaga cgtaaaatct tttctccatt cgctcgcatc cgcatggctt
    27781 cttccaatac aggaccacgg atatcataag caacatgctc taacttacta gacttgttat
    27841 attctttcat cttgtttcct caattcatca ggatagtaac attataccac tagaaagaga
    27901 atgcgacaag tttactgaaa tatgttacta gtttcgtata gaagaaaaac cttgctaaag
    27961 gcgaggttaa gaacgtagag atagcaggta ttttgcaaag acacatcaca taccaaaaga
    28021 taaacctaga aaaagcaagc ctagaaagga gtcataaaga agattaaaca tgaggaaaag
    28081 tccccatatc atcaagtaat cccaacgccc acttcgtttt gcaactagaa ataagattag
    28141 atggtagagt acatgaaaga ctaaaaatcc aataaaactt ggataaagaa gcggtaccag
    28201 actctctaat tgacagatca tgatcacttc taccaagact gaaactagga taattccata
    28261 ataaaggaaa tttgattttt gaaaagagtt tttcatcatt ctcccttcct tcacttcttt
    28321 cctgctatcc tttcttttta ttttatcata tatttatata gagtttaagc cctaatattc
    28381 ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa ttatagtaag
    28441 aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt cgcaatcgat
    28501 ggttctaagg aagcggactt ggcttttgtc aagggagttt attctgctct acgaaacgac
    28561 gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt atccaccttt
    28621 gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa agagtacgaa
    28681 aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat gggaaatcca
    28741 aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat cctcgttggc
    28801 gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga atacatactc
    28861 cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt ataatcacaa
    28921 agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta tggcgttcgt
    28981 aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca tatttttctt
    29041 cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc ttgccatctg
    29101 gaaaaatttt ccccatatta gcctgatgga caatatcaaa aatacgttct gggtcgaccc
    29161 ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca tccacttgcc
    29221 ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc ttatcaaggg
    29281 cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg gctgctcgaa
    29341 caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc tctaaatccc
    29401 aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc ttgaccttat
    29461 tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca aaatgttcca
    29521 aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca gcttccttga
    29581 cactgctact accatttccc atagcgaccg acataccgac gccagccagc atttcaaggt
    29641 cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat tctttcccaa
    29701 ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat gcaaaaggat
    29761 tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat tcttctggtg
    29821 tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg tcctcttcct
    29881 tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc cgagttaaaa
    29941 cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag gacatgattt
    30001 tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct tttttagcat
    30061 agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag actctgtctt
    30121 tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa tcgtccatca
    30181 attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc ccttgttctt
    30241 tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg ttgaccaagg
    30301 ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct ccccttttgt
    30361 gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa gaaaatcctt
    30421 gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc tgttgtgacg
    30481 agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca agtccacgcc
    30541 ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct ggtcctctac
    30601 cagaaaatta aagaggaagc agataactac gatggagtgg tgatcacaca cggaaccgat
    30661 actttagagg aaacagccta tttccttgat accatggaag ttccccatat gcctatcgtt
    30721 ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta taattaccta
    30781 agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt ggtcgttatg
    30841 aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa tgtcagcacc
    30901 ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat cctctacttc
    30961 aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt agtccctatc
    31021 atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt agaacacttg
    31081 gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac ggctcaaaaa
    31141 ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg ctttaacggt
    31201 attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa agcaggcgtt
    31261 ttctttgtta aagaactcaa tgcccaaaaa gcccacttga aactcctcat cgccctcaat
    31321 gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc ttcgaaaatc
    31381 tctgcaaacc acgtcacgtc gccttaccgt atgtatggtt actgacttcg tcagttctat
    31441 ctacaacctc aaaaacatgt tttgagctga cttcgtcagt ttcatctaca acctcaaaaa
    31501 catgttttga gctgacttcg tcagttctat ctgcaacctc aaagcagtgc ttttagctga
    31561 cttcgtcagt tctatctaca acctcaaaac agtgtgttgc gcagccttta accagccgcc
    31621 tagtccgctc tatggtattc attaagtcaa catctcttgt ttaagagcac aaaatcagga
    31681 aatcttctcg attccctgat tttttctatt tacgttttcg tgttgagcta cgttctgtca
    31741 aaccatgagg taagagaact tcacgttctt ccaactcttc cttatgcata atcttggtca
    31801 acatacgcat actaatggca ccaaggtcat aaagaggttg ggcaatcgtt gtcaagtttg
    31861 gacgggtaaa gcgtgagatt tgtgaatcat cactagtaat aatttcaaaa tcttctggca
    31921 cagaaacacc cttatcagcc aaaccgttca agactcctgc tgccaactca tcacctgtca
    31981 caactgctgc agttgcattt gatgaaatca aacgctctgc taaggcgtaa ccatcatcat
    32041 agctatattt agattcaaat accaaaccct cactataagt gattcctgct tttttcaagg
    32101 tttccttgta gccaactaaa cgaaccttac cattgatgtc atccactagc ggaccgctaa
    32161 cgaaagcaat acgctcattt tctttaacaa ggtaactcac tgcatcaatt gttgcttgct
    32221 tatagtcaat attgacactt ggcaactggt gctccacatc gacagttcct gcgagaacaa
    32281 tcggagtacg tgaacgcgaa aattctgagc gaattttatc tgtcaagtga taacccatat
    32341 agataatgcc atctacctgc tttgaaaaga gggtattgac aacagaaact tctttctcgt
    32401 tatcttcatc gctattagct aggacaatat tgtacttgta catttctgca atatcatcaa
    32461 tccccttagc caaactcgaa aaataaccat tggtaatatt tggaatcacg acaccgacag
    32521 tggttgtctt tttacttgca agaccacgcg caactgcatt tggacgataa tccaaacgat
    32581 caattacctc tagcactttt ttacgggtat tctcttttac atttttattg ccattgacca
    32641 cacggctgac cgtcgccatg gaaacacctg cttcacgagc gacatcataa atggttactg
    32701 tatcatctgc attcattcct tttcctgtcc tttctatctc acacattctt ttacaagtag
    32761 aggtgctgat tgaagctcta tatctactta caaaagtgaa gatgtgaaaa tttcgttttc
    32821 atatttctac ttattccatt ctatcactaa ttgtaaacac tttcaagtgt tttttgaaga
    32881 ttgattgaaa aaatttcata gaaaacctag gtttagctcc ttgctaccac cttagactaa
    32941 acaaaaagga ggaaactaag ccctcctaaa gttatagtaa aatgaaataa gaacaggata
    33001 aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt
    33061 ctagtttcaa tctactatag gtattgttcc attcactacc gtcaatttta gcacatagtc
    33121 ttcataaaat attatatcat cataaccaac cagattcttt tgcgatatta gctgcctctg
    33181 ttcgattacc agcatccagt tttgaaagaa tattggtgac atagtttcga atagttccgt
    33241 ttgagaggta aagctgatct gcgatttctt ggttggataa gccccgggcg attcccttta
    33301 agacagcaat ctcttgttct gtcaacggat tgggacgggt catcaccact tccatcaatt
    33361 caggcgaata ctccttgcgt ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa
    33421 tgcttcgttc ctttaataca taagcatcta ctccagcctt gaccgcacgt tcaaaatacc
    33481 ctgggcgctt gaaggtcgtc actacaacca cctttgtttc gagcttttct gctcgtatcc
    33541 actccaagac ttcgagtcct gtcttaacag gaatttctac gtcaaggatg gcgatatcta
    33601 cagactcctt ttctaatagt tgaattgctt cttgaccatt cttggcttgt aagacagact
    33661 ctacatctgc ttgaaaggca agcaactggc acatggcatc tcgcaacata ctttgatctt
    33721 ctgcgactaa tactttcatc tactttctct ccttataagg tagtcgaact tgcacttccg
    33781 ttggatgttt ctgactgatt acacttactt ctcctgaaaa tggagaaaca cgatctcgga
    33841 ctgtatggag ctcatctcct tttagaaaag caaagccgca gccatcatca cttactgtta
    33901 aaatgagttc tttctctgcc cgttctaatt tcaggtaggc cttcgacgct ttggcatgtt
    33961 tgataatatt ggtcaccaac tcaagcaaaa tcatggaagc cgttgactcc aattcttgag
    34021 taagactagc agtatctagt tggttatccg tttccacctc aattccagca atttctaaca
    34081 tctttttcac agtctctagt tcggatgtca aagttctaga cttaagattt tccacaatgg
    34141 ttcgcacttc attcatggaa tccttactga tctggtgaat ttcttttaat tccttttcca
    34201 cctgtggata agcctccatc tgaaataact gcaaggctaa atctgtcttg acactcaaca
    34261 tagcaaaggt atgtcccaag ctatcatgca aatcctgacc gatacgactg cgttcatttt
    34321 cagcaagcaa tagatttatc tgggcatttt gcttagcctg agcttctttc aaatcctcca
    34381 caatacgaat ccgaaccaag ccaaaagtca ttaaatcgac aaaagcaaga attacaagta
    34441 gatagaatag aaactcaact tcgattctct gaaaaatcaa cagttggccc acaacaagga
    34501 cttgagcaag aagaaaagtc cagacatgta aagactttaa accacctacg ctgaaatgat
    34561 aacttaagag attggatagg aaaaagaaaa accagatata attaacagca acaaaggcag
    34621 tattcccaac tacataagtc agcatgaggc cccaatatag ccaagatagg cgctggctct
    34681 tagttgttaa aacacccaaa tacgccacta caaatagaat atcaatcaat aaatgccagg
    34741 cagaaagcca cccagtcact acaggtagga tgggaaaaag cataaaaatc aaactggccc
    34801 aaaacatata gtgtatgctt ttcagtcttt caagcattaa gcattctcct tatgaccttg
    34861 aaggtaaata gtcaaaccaa ataaaactgc tgaaaaaaca agtagataaa ctgtggctga
    34921 tagattgatg ccacccttgt ttaagaaggt cttgagtaac tccatcaact gataggtcgg
    34981 gagacactta ccgactgctt gcatccagtc tggaaataaa gagataggca tccagagccc
    35041 acctaaaaca gccaagccaa ggtaaagaag attgcccacg acagacatca gctgactagt
    35101 tggtaagagc gtcaaggtca agccaagcgc tacaaaagca atacttccca aaataagcaa
    35161 aatcgcagcc ccaacccagc ttcctagagg catctctaca cctcttacaa aatgcccaac
    35221 tgagaaaacc accaagattg aaaccaaata atcaaccagc atacttgtta tctttgatag
    35281 ataatattct accatattta taggactatg acgtaatgtt ttctgccagt tgttgatttt
    35341 atctgtatgt aaaacagctg ggaatgaaaa gatagctgtc gacatcatgg aaaaagccgt
    35401 catggagatg aggtaatcac gcataaaatt agctggtcca ccaggtgtgt cctggtacat
    35461 gcctgaaaag aataaataga aggctgtcgg catccctacg gataatagat aatagactaa
    35521 ttgtcgtttg gtcaatagaa attctatctt gtttagtgcg atccatcgtt tcatcttagt
    35581 catctccctt ttgtgtttct tcaaagattg tatccaacaa gctacgatta ttgacttcaa
    35641 tttcttgaat cctacatcct gcttgcacta acagttgcca aaaagcatcc gcttcacgtg
    35701 taactacttg caaagcatct tgtttttgtg accagttttc aaccaagtta gactgctcaa
    35761 tgacttcctt gtaagctaga ggaaggataa agtgcttttc aatctcctca ctgcgtatgg
    35821 ctagaggtgt tgtatcgcga atcaaccctc ccttattcaa gaccaagatt cggtccgctg
    35881 tatgctctac ctcttcgatg taatgggacg aatagagaat ggtaactccc tgcgctttta
    35941 gatcctgaac aatctcccaa aaacgttggc gggttgaggt atccatggcc gcagttggct
    36001 catctaaaaa gacaagtttt ggtcggccaa tcaaggtcat gacaaaagag aaaagacgct
    36061 tttgcccacc tgacaatttt tctgcaaatt gctctttttg ttgctggtca aactgcaata
    36121 gttgatcgat ttcctgatta ctcaagtgat ttggataaat tttttgaaag aaagcaatca
    36181 actcttttac ctttagtttc tgaacgatta cattctcttg agggagatag gatctagtgt
    36241 agtctaactt agagctcgtc actggcaagc cttggatgga tacttgaccg cttgtgacca
    36301 gtttatctcc aagcagacag tccaagagtg tggtcttccc agcaccattg ggcccaatca
    36361 aggcgacgca ttcaccttca gctacctcaa aggaaatatc cttcaaaata gccttgccct
    36421 tgatgttttt atttaggctt tctaccttaa tcatgttcat gatattctcc tttcagccac
    36481 tcctttccca taggaaaggc gataaaaatc ataaattcta gtccccaggc accgcgaatg
    36541 gcttggtgaa ggaaggcttg atcaaaccaa cctgtaaaca tttctaccaa ccatactact
    36601 agtgatagtc caataaaaag atagagaaac gcttttttca tttttcaaac tcctttttca
    36661 catctgagac taatttcaaa ccttctcgga taagccagga catcattcca aatcctgcaa
    36721 atagctccca aggaaaatga taaaatcctt catccaatcc tgaaaacatg agataagtca
    36781 tgactcctgc ggttactaga ctcactgcga caatcatttt atttttcatc tcttcttcct
    36841 ccatttcata cttcaattat agacttttga agtttgcgga gctagatgct tctgtcacta
    36901 ggaaatatga caactgtcat aaaagattct gttcaaaaca agcaagatac actatacaat
    36961 aaaacacaat cagaaaaatc taaggcaact tcctcaaaag agatatcaaa cccaattcac
    37021 accataatgt aaactaatac ttatttaaaa tcaaaaagag tagaaatttt tatcagacaa
    37081 acacatatat agtgtattga atctataaca gtaggcctta aatactaaaa tatttctata
    37141 aattaattta actttcctga tagagctgtt catatcttat ttcaattctc taaattatac
    37201 gttgaacaaa acccttctat ttctttctta aaaatttata agagttataa aatctgttaa
    37261 atttcaatgt gtatacctaa actacggtat ttattgaaaa aactggagac aaaaagtata
    37321 cgttgccaaa atgaattact gaaaatcaaa aaagagagaa ccaaactgat tccctcttaa
    37381 tgtatataat atctagtttt aaaaatacac actcacatat ctctgt
//
LOCUS       DAVDHZ010000020        36614 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000020 DAVDHZ010000000
VERSION     DAVDHZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.020"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            111..1079
                     /locus_tag="VUR46_001160"
     CDS             111..1079
                     /locus_tag="VUR46_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET5456596.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRCMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESVFEDIYAD"
     gene            1095..2062
                     /locus_tag="VUR46_001161"
                     /pseudo
     CDS             1095..2062
                     /locus_tag="VUR46_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
     gene            2279..3322
                     /locus_tag="VUR46_001162"
     CDS             2279..3322
                     /locus_tag="VUR46_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET5456597.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYSEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            3386..5071
                     /gene="lpdA"
                     /locus_tag="VUR46_001163"
     CDS             3386..5071
                     /gene="lpdA"
                     /locus_tag="VUR46_001163"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET5456598.1"
                     /translation="MPKVGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPVMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIATKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            5139..5495
                     /locus_tag="VUR46_001164"
     CDS             5139..5495
                     /locus_tag="VUR46_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET5456599.1"
                     /translation="MMKYIFSEEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFT
                     SGKVEVFANVTESKIQDIKIYGDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITR
                     YFAGISREEIAEAVVG"
     gene            complement(5561..6838)
                     /gene="ltrA"
                     /locus_tag="VUR46_001165"
                     /pseudo
     CDS             complement(5561..6838)
                     /gene="ltrA"
                     /locus_tag="VUR46_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(7539..8609)
                     /gene="xerS"
                     /locus_tag="VUR46_001166"
     CDS             complement(7539..8609)
                     /gene="xerS"
                     /locus_tag="VUR46_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET5456600.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDLVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(9193..10743)
                     /locus_tag="VUR46_001167"
     CDS             complement(9193..10743)
                     /locus_tag="VUR46_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET5456601.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFILVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQILGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(10759..11538)
                     /locus_tag="VUR46_001168"
     CDS             complement(10759..11538)
                     /locus_tag="VUR46_001168"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET5456602.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(11525..12376)
                     /gene="ylqF"
                     /locus_tag="VUR46_001169"
     CDS             complement(11525..12376)
                     /gene="ylqF"
                     /locus_tag="VUR46_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET5456603.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTCALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(12636..17750)
                     /locus_tag="VUR46_001170"
                     /pseudo
     CDS             complement(12636..17750)
                     /locus_tag="VUR46_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(17799..23015)
                     /locus_tag="VUR46_001171"
     CDS             complement(17799..23015)
                     /locus_tag="VUR46_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET5456604.1"
                     /translation="MEKYFGEKQQRFSFRKLSVGLVSATISSLFFMSVLGSSSVEAQE
                     TQETKGVHYKYVTESELSSDEKKQLVYDIPTCMENDDETYYLVYKLNSQNQLGELPNT
                     GSKNDMKTLVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSAHALENN
                     LLLNYNTDYELTTGEKLPLPKEISGYTYIGYIKERNITSESKVNNQEKSVDTSKNQQK
                     VDYTIAPNFIESPSKIQVINGQYETVPEFRDGQVGAVATESAATKADTLSSDMNSEVE
                     SHSIPPTVDSSQNGENLGKQGEDATPVEKPKEQEPEKTEEVPVNPTEGTTEGTSNQGA
                     KNPVQPAEESTTNSEKISPDTSNENTGEVSSNPSDSKPPVEETNKPEKDESKDETSTK
                     PENSAHPITESGQTEPDQPKGNSPEDVSTESKTSNSNESEEIKHKTEVEPDKKVEEQE
                     KTIELRSVSDVELYSYEGNQSKQHTSLDKVPDNKSAYFIKVKSAKFKDVLLPVSNIED
                     TTKDGKAVYKITARLEHLKQSVDNQYQDNFTYYLPKLVQNDSPIYTSFKKLITDMNSR
                     PSGTFTLGATMNAREFELNENQESYVTSKFTGTLIGSHQGKHYAIYNLKKPLFNTLNN
                     ATIQNLTLKDVNISGKNHVASVAKEATNSSTLDNVHANGIIAGELGIGGLVQKVDNST
                     ISNSSFTGRITNTFVTTSQYAIGGLVGQLTGTNASVDRSIATVTISSNAEYSNQTIGG
                     IAGIVENNATVQNSYAEGEINNVKPFARVGGVAGSLWTNGSSTEDNSGILQNVLSDMN
                     ITNGNAISGYHFNGMKKKAVYSNKDNKVVNVQAVGDEVMSIDSTVERGTEIEKTAVQA
                     KKEQITKKHTITVEDFTNSVKQDVDYTKATHYQVARDIAYKNIEKLLPFYNRDTIVKY
                     GNQLSTDHNLFKKELLSVVAMKNEEVVSDITSNKNSINHLLLHYKDGTSEKVNVTYHS
                     DFANLAEYTIGTTGLVYTPNAFLKDYTSIIDRVKNDLNTVQYDPTSLKNLLGISDNVK
                     LTELYLDEQFAKTKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLT
                     YLERWYDFKFDKASAKDLLMFHMDFFGKGNTSPLDTIIELGKSGYNNLLAKNNVVTYN
                     ALLTNNYGTKDLFSALEGYRKAFAPTQTNNDWFKSQTKAYIVEEKSNILEVKANQEKA
                     GSKYSIGVYDRITSDSWKYRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNKEHQA
                     SGDLNSFVEENARETAKRQRDHYDYWYRILDEKEREKLYRNILLYDAYKFGDDHTEGK
                     AKKVATFDDPNPAMQHFFGPVGNKVGHNEHGAYATGDAVYYMGYRMLDKDGAITYTHE
                     MTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPNDATITINSILKHSKSDSTEGQ
                     RLQVLDPTTRFNNADDLKQYVHNMFDVIYMLEYLEGKSIISQLSATEKMTALRKIENK
                     YVKDREDGNEVYATNVVQNLTEEDAKKLTSFENLIDNNILSAREYKSKEYERNGYFTI
                     KLFAPIYAALSSDIGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEVAKQNGKKI
                     TIYGKERGLVTDELVLQKVFNGQYETWTEFKKAMYNERVAQFDRLNKVTFNDTTQPWQ
                     TFAKKTTSSVDELQKLMDVAVRKDAEHNYYHWNNYNPDIDSEVHKLKKAIFKAYLDQT
                     DDFRSSIFENKK"
     gene            complement(23254..24432)
                     /locus_tag="VUR46_001172"
     CDS             complement(23254..24432)
                     /locus_tag="VUR46_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456605.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTKKV
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFSPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERVYQDYFGFTETLTQEERKWAKIFFGKNRTERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNPYFRELPEEKSRLARLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKESLQADHLSSAQESWIEGILLNCIKPFLERLVI
                     "
     gene            complement(24450..28100)
                     /gene="addA"
                     /locus_tag="VUR46_001173"
     CDS             complement(24450..28100)
                     /gene="addA"
                     /locus_tag="VUR46_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET5456606.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGHGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQTFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILEKFPQVREAYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAKNPHEGKLILLKENFRSSSEVLSATNDVFEGLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKVEFLLYDKDDTGEEEEGQAETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIGMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKEYPAAK
                     NGKLNSTTRLQARNFQDWLWAVSKVFTKDKLNFSYRFVGEDQLTREAIGELKTKSPLQ
                     DSSQADNRQSETIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVDKKISFDLPDFSSKEKVTGAEIGSATHELMQRIDLSQQPTLASLTETLK
                     QVQTSPAVRDKINLAKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYEGRIVLFDYKTDRYDEPSQLIDRYRGQLALYGEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(28097..31372)
                     /gene="rexB"
                     /locus_tag="VUR46_001174"
     CDS             complement(28097..31372)
                     /gene="rexB"
                     /locus_tag="VUR46_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET5456607.1"
                     /translation="MKLLYTDIRTSLTEILTRKAEELVAAGKRVFYIAPNSLSFEKER
                     AVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLRYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLIAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(31572..31730)
                     /locus_tag="VUR46_001175"
                     /pseudo
     CDS             complement(31572..31730)
                     /locus_tag="VUR46_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            31901..32545
                     /locus_tag="VUR46_001176"
                     /pseudo
     CDS             31901..32545
                     /locus_tag="VUR46_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            32645..32854
                     /locus_tag="VUR46_001177"
                     /pseudo
     CDS             32645..32854
                     /locus_tag="VUR46_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            32754..33203
                     /locus_tag="VUR46_001178"
     CDS             32754..33203
                     /locus_tag="VUR46_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5456608.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSSLQRANERLKKPIPKHLSPHIFRHTTISILSE
                     NKIPLKTITDRVGHSDSEVTTSIYTYVTKNMKDEAINVLDKVMKKIF"
     gene            complement(33341..34645)
                     /gene="eno"
                     /locus_tag="VUR46_001179"
     CDS             complement(33341..34645)
                     /gene="eno"
                     /locus_tag="VUR46_001179"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET5456609.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            34809..35255
                     /locus_tag="VUR46_001180"
     CDS             34809..35255
                     /locus_tag="VUR46_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET5456610.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(35252..36277)
                     /locus_tag="VUR46_001181"
     CDS             complement(35252..36277)
                     /locus_tag="VUR46_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET5456611.1"
                     /translation="MADVEYLLCPVGDGGEGTVDAIRHSLDLKEKWIQVTDPFGQKEA
                     MRYFQKGELALFEVADLVGLGKIPLEKRNPLQIQTCGIGELILHLISKGIKDIYIGVG
                     GTASNDGGLGIAAGLGYQFYDRDGNVLPASGQSLLNLASVSTENCYKIPEGVQIHILA
                     DVVSPLCGHQGATYTFGNQKGLHPTMFAVVDQAIQDFYEKFSPATLEIKGAGSGGGLA
                     GGLCAFAQASIVSGIDTCLDLINFNKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRT
                     PVGVPVIAICGSLAEDLPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGH
                     LLNMCKI"
     gene            complement(36274..36390)
                     /locus_tag="VUR46_001182"
     CDS             complement(36274..36390)
                     /locus_tag="VUR46_001182"
                     /inference="COORDINATES: protein motif:HMM:NF014634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET5456612.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIAEASNNR"
     gene            complement(36399..>36614)
                     /locus_tag="VUR46_001183"
     CDS             complement(36399..>36614)
                     /locus_tag="VUR46_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET5456613.1"
                     /translation="KKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAK
                     EVLKKEIPHHVDKRDFLEVLPLIDRLE"
BASE COUNT        10508 a         7419 c         6943 g        11744 t
ORIGIN      
        1 ttacggggtt ttctttttta ttttgtgaaa tttcttttag aaaaactttg acagtatttg
       61 ccaaaagcgg taaaatagta aggtaagaag aaagttagaa aggcaagaag atgtcaactt
      121 tagataaaaa tcttttgcta gaaatgttcc gtaagatgga agaaatccgt tgcatggact
      181 taaaaattgc acaattagta aagaaaggga aagtgccagg aatgacgcac ttttctgttg
      241 gtgaagaggc agctaacgtg ggggctatgt tagctctcaa tccagatgat ctgattacct
      301 caaaccaccg tggacacggg caagctattg ctaaagggat tgacctcaac ggaatgatgg
      361 ctgaaatcct tggtaaatac actggaacct gtaaagggaa aggtggatct atgcatatcg
      421 ctgaccttga tgctgggaac cttggtgcca atggtatcgt aggtggtggt atggggatcg
      481 ctgtcggtgc agccctcagt cagcaaatgc aaaataccgg taaaatcgtt gtttgcttct
      541 ttggagatgg tgcgaccaat gaaggtgttt tccacgaagc agtgaacatg gcttctatct
      601 ggaacctgcc agtcattttc tattgcatta acaacggtta cggtatctct gcggatatca
      661 agaaaatgac caatatagaa catatccatc aacgtagcgc cgcttatgga attcctggaa
      721 tgttcatcga agacggtaac aatgtcatcg atgtctatga aggatttcag aaagctgtag
      781 accatgttcg cagtggcaat ggtccagtct tgattgaaag tgtaacttat cgctggctcg
      841 gtcactcatc atctgaccct ggtaaatatc gtacgcgtga agaagtggaa ttgtggaaac
      901 aaaaagatcc aatcgaaaac ctccgcaatt accttattga aaataacatt gcaagtgccg
      961 aagaattgga agaaatccaa gcgcaagtaa aggaagcagt agaagcttct gttaaatttg
     1021 cagaggaaag cccattccca ccgcttgaat cagtctttga agatatttac gcagactaag
     1081 gagaaagaga taaaatggaa acaaaaacaa tgtccttccg tgacaccatt atccttgcta
     1141 tgtctgagga aatgcgtcgc gatgaaaatg tgttcttgat gggagaagac gtcggtgtct
     1201 ttggaggaga cttcggtact tctgttggaa tgcttgaaga atttggtcca gaacgtgtcc
     1261 gtgactgtcc gatttctgaa gctgccatct ctggagcagc agcaggagca gccatgacag
     1321 gacttcgtcc aatcgtcgat atgaccttca tggacttctc tgttattgcc atggacaata
     1381 tcgtcaacca agctgctaaa acacgttaca tgtttggtgg taaaggtcag gttccaatga
     1441 ctgttcgttg tgcagctggt aacggagttg gctctgccgc ccagcgctca caatctcagg
     1501 acttaaggtt gtggcacctg gaacacctgc ggacatgaaa ggcctgctta agtcttctat
     1561 ccgtgataac aacccagtta ttatacttga gtacaagtca gaatttaacc aaaaagggga
     1621 agtgccagtt gatccagact acacaattcc acttggggtt ggtgaaatca aactccaagg
     1681 aacggatgta acagttgtta cttatggaaa aatgcttcgc cgtgtggttc aagctgctga
     1741 agaattagca gaagaaggaa tttcagttga aattgttgac ccacgtaccc ttgttccgct
     1801 tgataaggat atcatcataa actcagtgaa gaagactggt aaggttgttc tggtcaacga
     1861 tgcccacaaa acaagtggct atatcggtga aatttcagct attatttcag aatcagaagc
     1921 atttgactat ctagatgcac caatccgccg ttgtgcagga gaagatgtgc cgatgcctta
     1981 tgcacaaaac ctagaaaatg caatgattcc aacagttgaa agtatcaaag atgcaatccg
     2041 aaaaacttat aacaaagaat agagttacat aatataagtt atgtaactaa aacaaagctg
     2101 acgagaaact ttatatcttt taggtgcaga gctcttcgtc attaatatct tagattagag
     2161 cacgggctaa aagctcggaa aaaagataaa tctccttggc ttcatcgaag ccaaggagat
     2221 ttcctatttt tcagtcgctt ttgacgccct ttgtatcata aatagaattg gagagatcat
     2281 ggctgatgac aagctaagag cgactcctgc agctagaaag ttagcggatg atttagggat
     2341 aaacctctac gacgtttctg gctcaggtgc aaacggtcgt gtccacaaag aagacgtgga
     2401 aacttataaa gacacaaacg tggttcgcat ttcgccactt gcaaaacgaa ttgccctcga
     2461 acataacatt gcttggcagg aaatccaagg aaccggtcat cgtggtaaaa tcatgaagaa
     2521 ggatgttttg gccctgcttc ctgaaaatat cgaaaacgat agcatcaaat ctcctgctca
     2581 gattgaaaaa gtggaagaag tccctgataa cgtaacacca tatagtgaaa ttgagcgtat
     2641 tccaatgaca ccaatgcgta aggttattgc ccaacgcatg gttgaatctt acttgactgc
     2701 gccaaccttc accctcaact atgaagttga tatgactgaa atgttggctc ttcgtaagaa
     2761 ggttcttgag ccaatcatgg aagcaactgg gaagaagact actgtaacag accttctttc
     2821 gcttgcagtt gttaagactc ttatgaaaca cccatacatc aacgcttcat tgacagaaga
     2881 tggcaagact attatcactc acaactatgt caatcttgcc atggcagttg ggatggataa
     2941 tggattgatg acacctgttg tttacaatgc tgagaagatg agtctttcag aactggttgt
     3001 agcctttaag gatgttattg gccgtacctt ggatggtaaa ttggctccaa gtgagttaca
     3061 aaattcaaca ttcacaatca gtaatttggg aatgtttggt gttcagtcct ttggtccgat
     3121 tattaaccaa cccaactcag ctatccttgg tgtcagttcg acaatcgaga agccagttgt
     3181 cgtcaatggt gaaattgtga ttcgcccaat catgagttta ggattaacca ttgaccaccg
     3241 tgtcgtagat ggtatggctg gtgctaagtt tatgaaggac ttgaaagagt tgattgaaac
     3301 gccaatctca atgttaattt aagagcaaga gtattcattt ttaagatata gataaaggaa
     3361 gcaagacatg gccttagaag taattatgcc aaaagtcggc gtggatatga cagaaggaca
     3421 aatcgtccaa tggaataaaa aagtcggaga atttgtaaaa gaaggagaaa tccttttgga
     3481 aatcatgact gataaagtca gcatggaatt ggaagccgaa gaagatgggt acttgattgc
     3541 cattctcaaa ggagatggtg aaactgtccc tgtaacggaa gttatcggtt accttggtga
     3601 agaaagggaa aacatcccaa cagctggagc agcatcgcca gaagctagcc ctgtacctgt
     3661 agcaagtacc tcaaacgatg atggtaagag cgatgatgct tttgatatcg ttgtgattgg
     3721 tggaggtcct gctggttatg ttgcagccat taaagctgcc caattcggcg gtaaggttgc
     3781 ccttgttgag aaatctgaac ttggtggaac ctgcttaaac cgtggatgta ttccaaccaa
     3841 gacctacctt cataacgctg aaattattga aaatatcggt catgctgcaa atcgtggtat
     3901 cgtgattgaa aatcctaact tcactgttga tatggaaaaa cttttagaaa ctaaatctaa
     3961 agttgttaat actcttgttg gtggtgttgc aggacttctt cgtagctacg gagttactgt
     4021 tcataaagga attggtacaa tcactaaaga caagaacgtc ttggtaaatg gttctgaatt
     4081 gcttgaaacc aagaaaatca ttcttgctgg tggttcaaaa gtcagcaaga tcaacgtccc
     4141 tggtatggaa tctccacttg tcatgactag tgatgacatt cttgaaatga acgaagtgcc
     4201 agaaagcctt gttatcatcg gtggtggagt tgtcggtatc gaactcggtc aggccttcat
     4261 gacatttggt tcaaaagtga ctgttatcga aatgatggac cgtatagttc cagttatgga
     4321 tgcggaagtt tctaagaacc ttcgcttgat ccttgagcgt aaaggaatga ccatcttgac
     4381 tggtactaaa ctgcaagaaa tcattgagga aaatggtcaa cttcgtatca aggttgaagg
     4441 aaaagacgat atcatcgcaa ccaaagctct tctttcaatt ggtcgtatgc cagaccttga
     4501 aggtattgga gaggttgagt ttgaattgga tcgtggttgt atcaaggtca acgaatacat
     4561 ggaaacttca gttccaggca tttatgcacc aggtgacatc aacggtacta agatgttggc
     4621 tcacgcagct ttccgcatgg gtgaagtttc cgctgaaaat gcccttaaag gaaatcatgc
     4681 agttgccaaa ttgaatttga ctcctgcagc catctacact ctccctgaag tagcagcagt
     4741 aggtttgaca gaagaacaag cccgtgagaa atacgatgtt gccatcggta agtttaactt
     4801 tgctgctaac ggtcgtgcta ttgcatctga cgctgctcaa ggtttcgtaa aagttatcgc
     4861 tgataagaaa tacggagaaa tccttggtgt acacattatt ggtcctgcag ccgcagaatt
     4921 aataaacgaa gcatcaagca tcatcgaaat ggaaatcact gttgaggaaa tgctgaagac
     4981 catccacggg cacccaactt actctgaagt gatgtacgaa gcgtttgcag atgttctagg
     5041 aatggccatc cattcaccta agaaaaaata aaacgaaaat agattagact ggaaggttat
     5101 ttccagtttc tatcatatat catataaagt aaagggatat catgaaatac attttttcag
     5161 aagaagaatt ggccgaaatc aatcgcatca aggatactaa gtttggaact tgggactgga
     5221 actatggtaa atcacctgaa tttaacgtcc gtcgtggaac caaattcact agtggtaagg
     5281 ttgaagtctt tgctaacgtt actgaatcaa aaatccaaga catcaagatt tatggtgact
     5341 tctttggtat tgaagacgtt gctgcagtag aagatgtcct tcgtggggtg aaatacgaac
     5401 gcgaagatgt tcttaaggcg ctaaaaacca ttgatatcac acgctacttc gctggtatta
     5461 gccgtgaaga aatcgctgaa gcggtagttg gataaatcga gtaggggata atctctagcc
     5521 cctctcacac caccgtacgt gccgttcggc atacggcggt tcaactaact tttaacgcat
     5581 gtcgttcaag gtaataatcc aaacacgaaa ccagtccacg tttttccagg actggttttg
     5641 atatagcacg tttaagtacc tacttctgag ctactaattg ataatggtcg tcccagccag
     5701 ataccttatc tgctatccat ttaggaactc ctaacttaag caatccccat aatcgtctcg
     5761 atttcttctt ccattgcttc cagataatca ctcgtaggcg agtacgcaag cgctcatcta
     5821 tgctagtgac tatacttttc atattcccca atgagaaata gtttatccag cctcgaatgg
     5881 acaaattcag ttgctcaata cgtcttgtta agtctatact ccatttcatc tgtgttagtt
     5941 tcttcaattt aagcttaaat ctccgaacac tatcttgatg tggacgactt ttccaaccat
     6001 ctgatgattt ccagaacccg aaacctagat atttcaactc tcttggtctg gtaatcttag
     6061 tcttggttat gtttactttc aaacctagcc gtttctcaat aaaataactg actgaataca
     6121 tcacacgctt agcggcagcc tcgcttccga ctgtaatcac acaatcatct gcgtagcgca
     6181 caaatcgaag tcccctcttt tctaattcct tgtccaattc attaagcatg atattggata
     6241 agagaggaga taaatttcct ccctgtggcg tgccaactag cgttttatga cgctgaccat
     6301 taatgataac acctgaatga agatacttac gaatcaagga ttccgtatct ccgtcttcga
     6361 taatgttatg tactaaggac atcaatctat cttgagaaac cgtatcgaaa aatttctcta
     6421 ggtctatatc cactatccac tcatagccgt catttaagta ctctaagaac ttcatgatgg
     6481 ctttttcaca tgacctattt ggtctgaaac cataactcgt atctgagaaa tggggttcac
     6541 aaatggggct catgacttgg acaatggcct gttgaatcat tctatccata actgttggaa
     6601 ttcctagttg acggatgcct ccgtttggtt taggaatctc aactctaaga actggttgag
     6661 gcttatattt tctctgtttt atcagttcct tagtcaagcg ccagttttgt ctgagataat
     6721 tatccatctc ttcgatagtc attccatcaa tcccagctga gcctttattg gattttactt
     6781 gattgtaggc ttcaagcata ttttcgcgtg ataatatctt atctagcaat tttgacatgt
     6841 gcgtattcct ttcttgtttt ggtgcctgag ggatatctta tattggtgaa ccttcatcta
     6901 gtcaatacgt gacagaggcc agttctataa gaccgcttgt tttacagaca caattgaagt
     6961 aggattactt caattagttg ttcacccctt cgctccactt ccattacaga agtttcctca
     7021 ctactatggg ttcggctgac ttctcatgat tcgttgttac tacgctttca tcgctcatga
     7081 gacctcacgg gataagtcgt acatctttcc tcgtttatac aagatatgag gacgttaaaa
     7141 ggttacagtg aaaataggaa atctgacgca gagtctttag actctagaaa gatttatctt
     7201 tttcacacaa accttagtcc gaattcaatt actctcgtga tttacgcata taggttacga
     7261 ctaccttttt ggactttaga gtttgaggcc ccttatccgc tatatacgcc ttactatcac
     7321 gttcctgttc gtagagccac gatttcgcta tcccttcctc tccctgctac ctcacgatag
     7381 tcaggcttgg gaatcgctat tgggttcacc ggtagcgggt gcccacggag gacttacacc
     7441 tcagatgcac gacatgcccg tcgtacttca aaaagaagtt ggccaactaa ccaacttctt
     7501 tttttgatat ttatttacat aatttaaaat acgtaaaatt ataaactatc cagagcattc
     7561 ttttgttcat cactaacaat atgggtatag aggtcagtga cttgtgtgct agcatgccct
     7621 agttggtgac tgactaaaac ttgtgattta gtcgcatcat agagcctagt tgctagcgta
     7681 tggcgcagtt tatggggggt tacacgtact ttaaaatcct ctgagtattt agcaaccatt
     7741 ttctcaacgc tagaagcatc gatacgatta ggaacacctc tgtagagagt taaaaaaagg
     7801 gctgtatctg ttttttccgt tttatagcgt tgattccgaa tggccagata attctctaaa
     7861 taaggtttag caaaagcagc gacattgact aagtcacgtt tgccaccttt tcgagtaaca
     7921 tcaataacca tcatttttag attgagatct cttagatcta gattaacagc ttcagataag
     7981 cgaacaccag atgccaagag aagggcaata atggctaaat ctcgttcttt atttttgttg
     8041 aatgatgaga gagctcgatt tgaaagctgt tgtgggtgct cttgatcgat ataagttaga
     8101 aaaccttctg tttcatcacc tagaaagagt ttttgcttga tattttcagc tctggcagca
     8161 agggtttctt tctttttctt ggttgaaact tttttcatta cattacgata gaaataaggt
     8221 tccccctgat cgttttcaac ctcctcggtt agatacttgt aaagactaga aagtgctgat
     8281 aaggttcgat tgatagttgt ctgtgaaaca ccttgttttg ttgtattagc attcagcaag
     8341 ggacgttcac gtagataaag gataaaggat tccatgtctt tcttagacat attttccaaa
     8401 actgataaag gaatatcgga tattttatca gcgtttgaaa taccagactc caaaacccag
     8461 ctgaaaaatc ggtcatattc cttaaggtat tcgtacaggg ttgtaaaact gtagggcaca
     8521 gccagcttag attggtagta ttccagaaca taccagggca tgagttgttt tagtttgtcg
     8581 attcgttcca gtaaaatctc acgtttcatg tattttctcc ataagtaagt atactagtag
     8641 tatagcatag acttgtatat ttttcaagaa aattatagtt tttcagaaag atgttatagg
     8701 agtttttcaa agtgataaaa agacttagac ctacaaacaa aacagaataa ggaaaataat
     8761 aaaaatctca cccactaaac ttctgttaat actacataac tgaagagcta tataaggagc
     8821 tatgagatac aaaacacatt gtataataga ttgaaactag aatagtacat ctggacttct
     8881 aaaacattgc tagaaattga tttgattgtc ctgattgttt tatcatattt ctatttcatt
     8941 tcactatata attgctattg ttttcttttt catgatttta atcttactgt acagatttga
     9001 tacagtaaac tcctttctag ctttatactt tatcatttct aacttaatta tagtcttatt
     9061 tttaataaag ttcaattatt tatatgtaaa attcctcatc agtaaaaaat aaccgatctc
     9121 atttctgaga atcggttttc taaataaatc aagctgatta tttacataac ataaattatg
     9181 taaataatca tactacaaca acaaatcttt gacttttcca atttcacttt ttggaataac
     9241 caggtgaatc atatcaccca gatacattct ggttgagccg ttaactgttt ggctcttgcc
     9301 attatggact tgagttgtga tgaggacgtt gtgtggtaag ttgagttcat gaacttgttt
     9361 cccagcaatt ttatcagaaa ctggtatttc gataagtgta acttctcctt cgctagatac
     9421 ttcttctgga agcatttttt ccagcatggc ttcatagact ggcgtacctt tgagcaaatc
     9481 catgataata taagaaacaa gagtgacaag accaagtggc atgaggttgc gaatatctcc
     9541 taccatctca gttacgagga tcatagcggt taagggagct tttgatatgg ctccaaaata
     9601 gccactcatt cctagaatga caaatatagg gaattgctct tgactgacaa gtccaagatt
     9661 gacacagata acaccaacta aggcaccaag caaagaacca agagctaaaa tggggaggaa
     9721 aattcctcct ggcagtccac ttccatagct aatcatactc caaataaagc ggatcaaaaa
     9781 gtaagctaat aaaacttgga aactaaaatt ttgttcagtt aaagaaagga caagctgatt
     9841 tccgccacca aggatttgag gtaagaagat tccgactggt atgataagga taaaagccaa
     9901 gatgggataa taagctctat ccaaatggat tttttgacca atcaagtcat aaactcttcc
     9961 aacgtttaat acagctttct catagagaaa gcctgaaaat ccaaggaaaa ttcccatgac
    10021 gagatatatc caatactgat ctagggtcat gggaggaatg ttatctggca tatccaatac
    10081 tggtgtcaaa ccgaacatga gtagagacac aaagtttgct acgatgctgg ctgctagagt
    10141 tgagacccag aaaaagcgcg aaaaatggtg atagacttct tctacaacaa agagaagtgc
    10201 tgcaatagga gcattaaagg ctgcggctaa acctgctgca gctccactgg caatcaagga
    10261 gcgttcctct actggactgg atttgagcca cttggcaatt cctttaccac caactgctcc
    10321 aagttgaata ctgggtccct ctcgacccag catgagtcca ctggcaatag caagaatacc
    10381 tagcacatat tttttccaaa gaatgcccca ccagttgagg gacatgaggc ctttcagttc
    10441 ggcttcgact tgaggaattc ctgagccttt aatatctttt tctgaccgtg ttagtttggc
    10501 actgagccaa cagatgagta tataaaacaa aaccagtata aaaagattgc gcactaagta
    10561 cccttgatct tgataaactc cttgtatcag gtggaagccc ttttcaatta agaaacgaaa
    10621 ggatccgacg ataattccaa cgatgaggcc gacaatgatt cctcgaccaa cttgggatag
    10681 tatagtgctg gatgcaaagg cgaattcttt cttagaacgg actatttccg actgttcctc
    10741 catggtattt cctttcaatt aactttcttt tttacctaaa accagtgatt taacgggttc
    10801 aaagctggtt cggtgaattg gggtaactcc tagttttgtg aggccttcca gatgtttagc
    10861 tgtgccatat cctgcattag tagcgaaatc atagccaggg aactgctgat cgtattcctt
    10921 catcaattca tcacgtgtta ccttggctac tatagatgct gctgcgatag agagggagtt
    10981 ggcatctcct ttgataatgg aggtttgtga aatgggcaag tccagtttca tggcatcaat
    11041 caaaaggtgc tctggttgag ggctgagctg ggagattgct tcttgcatgg ctagtttggt
    11101 tgcttcatag atgttgactt ggtcgatgac ctgattatct atgataccaa ttccaatcga
    11161 caaggcttgg tcttgaacgg cttggaaaat ctccagatgt ttctttttag gaattttctt
    11221 gctgtcgttg agacctttaa tcttacaatt tttaggtaaa ataacggccg cagcgactac
    11281 aggaccagca agaggaccac gaccaacctc atcaatacct gcaattaagg tcaatccttg
    11341 cttataaagt tctttttcat aagaaagcat ggattccaag cgcaaatttt catctaattc
    11401 agcttgaatg gctcttttac gcttgctgat ttccttttga actcctgagc gattatcctt
    11461 ttcaagctct aaaaaaatag ggctttctaa ctccttgact gtcacaagga gttctttgat
    11521 ttctttaatc gttgccatcg aggtcttcca atgtatctaa ggtatagtta ccgagtttgc
    11581 catcacggac ttccttcacg aagagactgt aaaaacggtc atagtcatca cggaaaccga
    11641 gggcgcaggt catatccata ataatcacag gcgcttcttc ttcaattttc atttgtttga
    11701 agcgttcagc cagcttttct ggataatgtt ctttgaaata attgatacca aaaatggtaa
    11761 cctcatccat aggaagcaac tgatccttga tagctccagt caatgccaac ttaagtgcaa
    11821 cagtttcatc ctcaaactta ggccagagaa tccccggtgt atccaagatt tccagatctt
    11881 tattggtttt aagccattgt tgaccttttg tgacccctgg cttgtttcca acaacagcaa
    11941 tctttttacc agccaaacgg ttcatcagag ttgatttacc agcgtttgga atcccaataa
    12001 tcatggtacg caaggtttca atctgaatcc cacgttcttt ctggcgagca atcttatcag
    12061 ccatgagctt cttggccgca tctgttacaa cttttacagt cacttgctct ttggagttga
    12121 tagctagcgt ctggattcct tgtgattcaa aatactgacg ccattccttg gtcattgctg
    12181 gatcagccaa gtcggccttg tttaaaatca agagttttgg tttatcacca acaatcttgg
    12241 tcaacatagg attttgacta gatagaggca agcgtgcatc tactaaaatc gtcacaaaat
    12301 caacaaattt taaattttcc tgcacctgtc gacgcgcttt agacatgtga ccaggaaacc
    12361 attgaatagt agccattgag ttttttcctt tcgtagcaag gatttagatc ccctatttta
    12421 ttttactatt gtttgaacat agagagtttt caaatgaatg atgtccaaac agttcttgtt
    12481 ttatgacata gaaatctact ttatattata tcatgccttc tttattttgt ccgatgatag
    12541 ccttttaccc tatcttttac cctatataga aaaaagccat caaatgatga cttttcagag
    12601 ggagcaaaaa actgttccct ttatatttta aagatttaaa tgtctttttt gaacaatgga
    12661 ttaaagaaac cgtctgtgtt tttaagaagg gctttaaaga tcttggattt caagtccact
    12721 gtatttttga aatgattttt aatttttgga tctgacatac catcaagatc tttttgaact
    12781 gcttcagcaa ataaagtgcg caactcatca tagttgctaa tatggactcc atcaatatcg
    12841 atagcctcaa aacctttctt agctttagca agaacttctt cgtaccaatg tctcttccac
    12901 tcttcaaggg tactaaagtt tccttttgat actttagtaa ttattagctt atcgcttagt
    12961 aaaccatggt tgtttttatc cgcttctgct ttgtatttat ttgacacata actgataaat
    13021 ccattttcat aaccatagta accccacata cggaaagcat tgtgcttaaa cgataatgaa
    13081 ccaggtgcac catcactcgt atttccaccg taaattcctg ccatcatatt gacatttacg
    13141 taagctgatt ttggtgtaaa atcctctggt ctataacgtc cgttacctgg attaccatga
    13201 atggtcatga aattattatt tactaagtca tcaatggaat tcagtggtgt tgttctctca
    13261 gcgtctgtca agtcacgcac tttgtcccat tggtgaggag cacttagttt atttctatcc
    13321 attggtcgac gtatttcacg gtcaattttc ttgaaccatt tgctattgtc accatttaat
    13381 tttggaatta cagcatctgc ttcaacataa tccaacatca ttaacgcttc attgtagttc
    13441 ttcatgtagc gatcgatgtc ttcacgagtt tgtaacttat caggattata attgtaccat
    13501 tggttaccat cattttcacg gtgataagcc atgttaaggc ctaaagcacc atattctccg
    13561 tttggatttg ataccgatgg cgtttgcaac ataccttgag caaaggcttc taaatccgta
    13621 ccttggcgat gccaatgacc accatagtaa accatacgat cattaacgtg agtagtttca
    13681 tgtgtaaatg cggatgttcc aaaatcacta attaaatctg tcataacgaa ataaactgaa
    13741 tccatcggtt gcggtgctgc aaaaatatat gcatatgctc cgtatccata ttggtaagga
    13801 tgatacttcc caatacgacc aaagaattcc ctgactggat tatagtctgg ttttccattt
    13861 ctatgtccga atctatcagg ccagccacct ggagcgttat gattatccca tacaggagtt
    13921 ggaactacat tttgactctt aagaagttta tcgcggacat tatcagtagc aagacgtgac
    13981 caaaaatcta agtaattaac ttgctctttg gcacgtagat taatctcttt tttaaaggct
    14041 tcacgttctt cttcagtatt tttgttgtat ttttcaaacg aactaaatga gatagtatta
    14101 tacgttgaaa tcataaataa atgtgcattt ttcaagttaa gaagaggtaa aatcatacgc
    14161 ccatgctgtc cattattaat tccttcgtat agacgatatt ttttgttagc aaatgcaggg
    14221 ttcgttgatg gttgttcaac tacatacgca ttcttttcaa tagctttctt aaaccagtca
    14281 tttatatctg tatggttagt caatagcttc atattgtaat gtaagaatcc atttaattca
    14341 tttattccga ttgttccacc tatagtttca cgataagctt ctaaagttct atcaccttta
    14401 acatttcttt cacttgaacc aattttgatt aagaaatcta agatattaac attcttacca
    14461 taaaaatcag gtttaaacat cataatatct ttaattgata acttatcgta tttaaaacca
    14521 taatattgat ttaagtaggc aagtcccatc atgattttag ctttgttgtc ttcaactttc
    14581 ttcagtaaag cacgctcgac tgcttccccc catttaactg atgatcttca ttttctaaaa
    14641 tctgactaac aagtttttct aagtttcctt ttagttctgc gaaactttct tctaagtaca
    14701 agcctttaat atactccgtc ttcttctcag gagtatatta aaggcttctc acgtttatcc
    14761 atcaaagcac gaacttcatc tgaaagtaag gtaacactag ctaacttctc tttaataccg
    14821 cttgctaact ggttacgatt cttcataacc atatttggag tatagacaat gttttgacct
    14881 gctacatcat actcttttac ttgagctact ttagagtcag ttttagcagt tacagttaac
    14941 tcttcctttg taccatcagc atagtgaacc ataatcttat caatatctga caaatcagtt
    15001 acaaactgcc ctgctttcat acctgttaca gacagaacgg ttttcttaac aagattggac
    15061 tcatctgtta acttattccc ttggtttacg atccactctt tattatagaa cggttgaagt
    15121 ttttcaatat tgcgataggc ttgttcacgt tcagctttgt aatcttgcgt tgtcttatac
    15181 tcattatcac gagttgtcag gttgttgagt gtgtttacaa gtggatccgt gatttcatac
    15241 ttatcagcag tgatattgaa ggtggcaata cgtttatcag cttcagcttg gtctacaccc
    15301 tgaatttgtt ttgaacgttt atatgaaaca ttgcctgacg caacatctct cacatataca
    15361 ttgttcttga agtaatggaa tccaaagtct gggtcgcccg aatccactga accagaaccg
    15421 tacatgattt caccattgtt tactttcatc atgctgacgt tgttttcaac ccatccccaa
    15481 ttgtagttat cgtgaataac accaccactt tgaccatgat ttttaagtgt catagtacct
    15541 ttaacaacag atttcgttaa gcgacctcgt tgttttacat ccatagggtt tacaccatgg
    15601 tcaattttag caattagccc accgacctta gagttgttgg ctttgatatc agcatcaata
    15661 tatgagctat cgacattact tctccaactt tcactaacaa gtccaccaga ccaccagcct
    15721 ttatctccaa gactgttaat cttaccaata aatgctacat tgcgcatatt agcttcatct
    15781 aacttattaa cagcaccggt tacatcgtta tttcctgtta ctgaacctac tactttgata
    15841 ttttcaagtg tagagttctt aaacatatta ccgatagggg caactttatc agcccaaggc
    15901 atgttgatat ttacattacc caagttaaag tttttgagtg tagcaccttc agcttcatta
    15961 aacaaaggtc tttctaagtt atgaatcgtg tattgatgat tctctacact tgataaagta
    16021 cctctaaact taaccataac ataagcttta cctgctggct taacgttaac tgcattcaaa
    16081 tctgcaccaa gtttaaactc accggtagga tttgcttgca tatcttttgc taaatcatgg
    16141 aagttgtaat aaaccttatc ctcggtagcc ctcggttttt caaaataata agtgtaagtg
    16201 tctcttaact taccgtcttt gtcacgttga actaagtcag gtgcttttgc tgttaccttg
    16261 taaagttgct taccttcctc aatgacctct tcaatcttat caattgctaa acgggtcact
    16321 ttgttttctc tggaggttac ttttaagtaa tagttggtaa catcacttgg aagagaggtt
    16381 aagtgattac tatcactttc gacaccgctt tcgttcactt gtacgagact tgtgtttgca
    16441 atatctttca actcaacttt ctttaaatct aaacgtaaag gtctatcttc caaagtcgat
    16501 acttctgcac ccttacctac atcataagtc atagtagttg aaatcgtata atctttgtaa
    16561 taatccaagt tctctaagac ttgagataag ttatcggttt ttaaatcaac cgttggtttt
    16621 tcttttgtac cttttacaag aatttcaggc ttcatttctt tcaaaattgt tactgtttca
    16681 actggttcac taattttttt gccatgtaac tcttcatagc tagtaacaat ttgacgttcg
    16741 ccatcctcac caatttgttt aacagaatta tcgcctataa atttggtagg atcagattct
    16801 tctatagtgg ttttaggaat agtctctgtc cgaatatcgg tatgtaaaga aggtgactct
    16861 tctctttctg atgcaacttc tgaaactgta gatatcggct cagtatactc tggaatgttg
    16921 ctaacgggtg gctcaatcaa gtttccattt tcatctactc ctgctgtacc tactggctca
    16981 gtatattctg gtttctcagt tttaggtgct tcgtcaggaa ccatacctac aggttgagtg
    17041 tactctggtt tttcgctaac aggtggttca atcaagtttc cattttcatc cacttctgtt
    17101 gtacctactg gctcagtgta tgctagtttc tcatgaactt caggctcaac aaggtttgca
    17161 cctattggtt gcgtatagtc aggcttctca tgaatttctg gttccccttt ttcagtcaca
    17221 acttttggtt gctcaactgg cgaaacagtt gatgctggag aaactgacga aacagttcta
    17281 tcatcaagct ccaagtaacc aacatatctg taactggaaa tttgcaacac accatcacgt
    17341 ccagactcat ggatgttagc attcaaatta agtgctgaag cagttgatag tgtaactaaa
    17401 cctgtcgccc ctacaatcaa aaatgtagct atttttttcc tctttttatc ttttgtgata
    17461 atcacaataa gactcccgat agctaacaaa cccaatgcag tcataataga ttgagaactt
    17521 cctgtgtttg gtaatgcgtc tttttcataa accaaagcat atgactcttt tgatttatca
    17581 ggtctacctg atttcagttg agcacgctca ttttgtgtca aattactata atctaagtaa
    17641 tgataaggcg atgcaccaac aactgacggt gcgaataaaa gactccccaa gaataccgaa
    17701 ccaacaatac cctttatttt ccgaatggaa aatttatctt ttttaataat gacaattcta
    17761 attctctaca ttcacttttt atttcctaat agtaaacact attttttatt ctcaaaaatt
    17821 gaacttctaa aatcatcggt ttggtcaaga taagctttaa agattgcttt cttgagcttg
    17881 tggacttcac tatctatgtc tggattgtag ttattccaat ggtagtaatt gtgttctgca
    17941 tccttacgaa cagcaacgtc cattaatttc tgtaattcat ctacactgct tgtagttttc
    18001 ttggcaaatg tttgccaagg ctgtgttgta tcattaaaag taactttatt cagtctatca
    18061 aattgagcta cacgttcatt atacatagct ttcttgaatt ctgtccaagt ttcatattga
    18121 ccgttaaata ctttttgaag aacaagttca tctgtcacca atccgcgttc tttaccataa
    18181 atagttatct ttttaccatt ttgtttggca acttcttcgt attggttgga aatatatggt
    18241 accataccat ctttaaagcc tttagcagct agtagttcat aggctatacg acgtcccatc
    18301 aggtcacctg gtgttcctat atcactactt aatgctgcat aaattggtgc aaataactta
    18361 atagtgaagt agccatttct ttcgtattct ttagacttgt attcacgagc tgaaaggatg
    18421 ttattatcaa tcaaattctc aaagcttgtc agttttttgg catcttcttc tgtcagattt
    18481 tgtactacgt tagtagcgta aacctcattt ccatcttcac gatctttcac gtatttattc
    18541 tcgatttttc tcagggccgt cattttttct gttgcagata gttgactgat tattgatttt
    18601 ccttcaagat attctaacat ataaataaca tcaaacatat tgtggacata ttgcttcaaa
    18661 tcatctgcat tattaaatct cgtggttgga tcaagtactt gtaatcgttg tccttctgta
    18721 ctatccgatt ttgaatgttt taagatcgag ttgatggtga tggttgcgtc atttggatgg
    18781 tctggcgctt gtagtaatcc tttagcaaag aactctggtc ccagtccact tcttctgcca
    18841 tatccgccta gataaatgtc ctggtctgaa tcgtgcgtca tttcatgagt ataggtaatg
    18901 gcaccatcct tatccaacat acgataaccc atataataaa cagcatcccc tgtagcgtaa
    18961 gcaccgtgtt cattatgacc aaccttattt ccaacaggtc caaagaaatg ttgcattgca
    19021 ggatttggat catcaaaagt tgctactttt ttagcctttc cttcggtatg atcatcacca
    19081 aatttataag catcataaag caagatattt cgataaagct tttcacgctc tttttcatct
    19141 agaatacgat accaataatc atagtgatct cgctgacgtt tggctgtctc acgcgcgttt
    19201 tcttcaacaa agctatttag atcaccactt gcttgatgtt ctttattacg atatcgatca
    19261 taagcaccaa aacctagact agatatggtt gaaatgacaa atactgattt ttctggcaag
    19321 gtaagtagag gtagtaccat gttacggtat ttccagctgt cgctagtgat tcgatcatag
    19381 acaccgatag agtacttgct accagctttt tcctgattag cttttacttc tagaatatta
    19441 gatttttctt caacgatata agccttggtc tgtgatttaa accagtcatt gttagtttga
    19501 gtaggtgcaa atgctttacg atagccttct aaagcactaa acagatcttt tgtaccgtag
    19561 ttattcgtca gcaaggcatt gtaagtaacc acattatttt ttgccaagag attgttgtag
    19621 ccagatttac ctagttcaat aatcgtatca agaggagagg tatttccctt accaaagaaa
    19681 tccatatgga acataagcaa atcttttgcg ctagccttat caaatttgaa atcataccag
    19741 cgttctagat aggttaatcc tagcatcaag gcttctttgt ttcgcttgat tttatcaaca
    19801 atgtaattgt caattatatc attatttcca gaaacagctg catcagctga aagtaatttt
    19861 ttaagagtct cagtcaagtg ctctttggtc ttagcgaatt gctcatctag atagagttct
    19921 gttaatttaa cattatcaga gattcctaac aaattcttaa gagaagttgg atcatactga
    19981 actgtattta aatcattttt aactctgtct attatagatg tataatcttt taggaaagca
    20041 tttggtgtgt atactagacc tgtagttcca atagtatact cagccagatt tgcaaagtca
    20101 ctatggtagg ttacgtttac tttctcagat gttccgtctt tgtaatgtag tagtaagtga
    20161 ttgatagagt tcttatttga agtgatatca gagactactt cctcattttt catagctaca
    20221 acagacaaca attctttttt aaacaggtta tgatcagtag ataattgatt tccatatttc
    20281 acaatggtat ctctattata gaaaggcaat aatttttcta tatttttata tgcaatatct
    20341 cttgccactt gataatgagt tgcctttgta taatctacat cctgtttaac agaatttgtg
    20401 aaatcttcta cggttatagt gtgtttttta gtaatctgct ctttcttagc ttgaactgct
    20461 gttttttcaa tctcagtacc acgttctaca gtggaatcaa ttgacattac ctcatctcca
    20521 actgcttgaa cattgactac tttattgtct ttattactgt aaactgcttt tttcttcata
    20581 ccattgaagt ggtaaccaga aatcgcattc ccatttgtaa tattcatatc gcttaggaca
    20641 ttttgtagaa tcccagaatt gtcctccgtg ctagagccat ttgtccaaag ggaacctgca
    20701 actccaccaa ctctagcaaa tggtttaaca ttatttattt caccttcagc atagctattt
    20761 tgtacagtcg cattattttc tacgatacct gcaattccac caatggtttg atttgagtat
    20821 tctgcattac ttgaaatggt tactgttgca atagaacgat ctacactagc attcgtacca
    20881 gttaattgac cgactagacc accaattgca tactgagagg ttgtaacgaa ggtatttgtt
    20941 attcttccag tgaagctact attacttatg gtagaattat caactttttg gacaagtcct
    21001 ccgataccta gctcaccagc aatgattcca tttgcgtgaa cgttatctaa agttgaagaa
    21061 tttgtggctt ccttagcaac tgatgcgaca tgattcttac cagaaatatt gacatctttc
    21121 aaggtgagat tctgaatagt agcattattt aatgtattaa ataacggctt tttcaaatta
    21181 tagatagcat aatgtttacc ttgatgacta ccaattaatg ttccggtaaa tttacttgta
    21241 acataacttt cttggttttc atttaactca aactcgcgag cattcattgt tgcaccaagt
    21301 gtgaatgttc cacttggtct actattcata tcagttatta attttttaaa tgatgtgtag
    21361 atagggctat cgttttgaac aagttttgga agataataag taaaattgtc ttggtattga
    21421 ttgtctacag attgcttcaa gtgttccaat ctagctgtaa ttttatagac tgctttaccg
    21481 tcttttgtag tgtcttcaat gtttgaaact gggagcagta catctttaaa tttagctgac
    21541 ttcactttga tgaaataagc agatttatta tctggtactt tatctaagct tgtatgttgt
    21601 tttgattgat tgccttcata actatagagt tccacatcag aaacacttct tagttctatt
    21661 gttttctctt gttcttctac ttttttatca ggttctactt cagttttatg tttaatttct
    21721 tcgctttcat ttgaattgga tgtttttgat tcagttgata catcctctgg cgaatttcct
    21781 tttggttggt ctggttctgt ttgtccgctc tctgttattg gatgagcaga attttcaggt
    21841 tttgttgaag tttcgtcttt tgactcatct ttttcaggtt tatttgtttc ttcaactggt
    21901 ggttttgaat cactaggatt actggacact tccccagtat tttcgttaga tgtatctggt
    21961 gatattttct ctgaattcgt tgttgattct tctgcaggtt gaactggatt ttttgctcct
    22021 tgatttgagg ttccttctgt agtgccttct gttggattta ctggaacttc ttcagttttt
    22081 tctggttctt gttctttcgg cttctcgact ggagttgcat cttctccttg ttttccaaga
    22141 ttctctccgt tttgagaaga atctacggtt ggaggtatag agtgactttc cacttctgag
    22201 ttcatatcac tagataatgt atcagcttta gttgcagcgg actctgtagc tacagctcca
    22261 acttgtccat ccctaaattc tggaacagtt tcatactgtc cgttaatcac ttgtattttt
    22321 gatggactct ctataaaatt cggtgcaatc gtataatcca ccttttgttg atttttagaa
    22381 gtatctactg atttttcttg attatttact ttagactcag aagttatgtt tctctctttg
    22441 atatatccaa tataagtgta gcctgaaatc tctttaggaa gaggtaattt ttctcctgtg
    22501 gtcaattcat agtcagtatt gtaattcagt aagagattat tttctaaagc atgagccgat
    22561 acaagaacac catttcctat ccctgcaacc aatactaaat gtaatactgt tttattctta
    22621 acttttttct tagaaacggc aaaaattaaa atccccagag cagctaagct agcaccagca
    22681 actaaggttt tcatatcatt cttgcttcca gtatttggca attctcccag ttgattttga
    22741 gaatttaatt tataaacaag ataataagtc tcatcatcat tctccatgca tgtcggaata
    22801 tcatagacaa gctgcttctt ttcatctgat gatagctctg actctgtcac atatttatag
    22861 tgaacacctt tagtctcttg agtctcttga gcctctacag atgaactacc taatacagac
    22921 ataaaaaata aacttgaaat cgttgcagat acaagtccta ctgataattt tctaaatgaa
    22981 aaacgctgct gtttttcacc aaaatacttt tccatgattc ctccttgaaa tacaatttat
    23041 agatgttaca aaaaccttta ttatattagt gtgttatcta taaaaaatgc agtataattt
    23101 aattatacta ttaatttaca aaaaaatctt aaaattgagt tgcgctttca tactttgttt
    23161 tacgtgtaaa atacgaatgc gcagggtttg aatttcttat attctttttg gataaaatgt
    23221 aacctaccat gaaatttcca cggcaggtgt tattcatatc actaatcgtt ctaaaaatgg
    23281 tttgatgcag ttgaggagaa tgccttctat ccagctttct tgtgctgagg agagatgatc
    23341 tgcttggagg ctttctttca gaaaatctcg aacttgttct ggtgcgattt caaactcaaa
    23401 agctttcatt ttatagaaaa agtcgataag atgatctgat agatattcag ttgaaaatgg
    23461 aacttctcca ctttttcgat attctaataa gagccgagcc aatctggatt tttcttcagg
    23521 aagctcacga aaatagggat tgaggagcca ggtctgcttc tgctttcttt caattggatc
    23581 ctgactggct attcgttggt ctttttccaa ctctttttgg tattgtttgg ccttgatagc
    23641 ccgttctgtt cgatttttac caaaaaaaat tttcgcccac ttgcgttctt cttgagtcag
    23701 agtctctgta aagccaaagt aatcttgata gacacgctct gctgggccca tggctaggac
    23761 tagattgtct gcatattgct tggcgatttt atccctcttc ttgcgctctt tctctgcctg
    23821 gatacggagt tcttgctcgt aatcaatttt ctccttgcct agctttacaa gatagagttg
    23881 gtcatccgat ttcccaagta aaaagggttt gatacacttt tcaagaactt cctccatacg
    23941 agccttcttc ttgggctctg ccttggtcca acttcctcct tgaaagactt ctaggaagag
    24001 ttggtagtct ctctcaggtg agaactgatt gccacgatta ggtttaaaaa cacctttttc
    24061 ccagagccac tttagaagcc gctcgtcaaa gtcactttta ttgaccttga ttttttcctt
    24121 tttctggact tttttggtca gattttcaac ctttctgagc agtttttctt cctcttctag
    24181 ttgctggtca aggggcaatc gatgaaaatg acgaacacag tcgctaccaa tcggaaagag
    24241 gcgttggcct gtgacaccat taaagagttc gtaggcgtac ttgatggcat ttccacagac
    24301 acaattacta cggccgattc cgttaaaaat caaggaaact tcattccatt ccttggtagc
    24361 ttgttcccaa gtatcagctt ttgaagcctg taaaaccgca tcgtgcaggg attttctaac
    24421 tggaagtgtc atgaggtctc ctttctagat tatactttta caacttgaac ctcatcttta
    24481 ccgagtaaaa tcaagtattt ttcaatattt tcaatcgaat aggctcgtga taaagcctct
    24541 ccgtataggg ctaattgacc acgatagcga tctatgagtt gacttggttc atcatagcgg
    24601 tctgtcttat agtcgaacag aacgattctg ccctcgtaaa gcagatagcc atcaaggata
    24661 ccacgaacaa cgaaatcttc ctggctcttt tggtctcgtt tgagcatgga gaaaggttgc
    24721 tcgcgataga gatggtcggt attagcaaga atttcctgac cgagtgctgt gtcaaagaat
    24781 gcaagaattt tagcaagatt gatcttgtct ctgacagctg ggctggtttg aacttgtttg
    24841 agagtttctg tcaggctagc aagcgtcggt tgttgactga ggtcaattct ctgcatgagt
    24901 tcgtgggtag cactaccaat ctcagctcct gttacctttt ctttgcttga aaaatctggt
    24961 aaatcaaagc taattttctt gtctactgac tgaccttgac ctgcaatctc gacaccttcc
    25021 atatccataa caggttcgta aaatttcttg atttgacttg gggtttgaac actaggaagt
    25081 tcaatagctg cacggtgaag agtattataa acttccactt ctttcagcat ttccagagct
    25141 tctttaatag tttcagactg gcgattgtct gcttgggagc tatcttggag aggactcttg
    25201 gttttcaact ctccgatagc ttctctggtc aactgatctt cgccaacaaa acgataacta
    25261 aagttgagct tgtccttagt aaacacttta ctgacagccc aaagccaatc ttggaaattc
    25321 cttgcttgca gtctagtagt gctatttagt tttccatttt tagctgctgg gtattccttg
    25381 gcttccaact tttcacgaga acccttaccg acaagataga gctttttctc agccctcgtc
    25441 atggcaacat acagcagacg catttgctca gaatagcttg ctagctgtaa ttcttcttcg
    25501 ttctgcctat aggtcagact aggaatggag agtttgatgg ttttaggata gtggtcttct
    25561 actgcccctg tctccatctt ggcaatatat ttgacaccaa gaccattttg acgactgaga
    25621 atgacttctg acatagagtc ttgcttgttg aaatcttgat ccatattgag gataaagaca
    25681 taaggaaact ccagcccttt actcttgtgg atggtcatga gctctactgc atcttttggc
    25741 ggtgcgacgg ccacgcttgc caaatcgtgc tgggcttcta aaacttggtc aatcatacca
    25801 ataaaacgcg acaaaccttt gaaattgctc ttttcaaatt gatcagcacg cagtgctaag
    25861 gcatagagat tggcctgcct agcaggacca ttcggcaaag ccccaacata gtcataataa
    25921 aaacggtcgt tgtaaatctt ccaaatcaag tcatagagag agtgggtttt ggcatacaag
    25981 cgccaagaag ctaggatatc catgaattgc tttagtttct cagctagagc tgtgtgaatt
    26041 aagccttttt gactacttgc cattttttgt gcattgacca gtttctcata gagattttcg
    26101 tggactttat cctctgcttt ctgaagggac aaacgtgcta gctcatcctc atcgaaacca
    26161 aacattggag acttcataag ggcaaccaag gcgtagtctt gcaggggatt gtgaatgaca
    26221 cgaagggtgt ctagcatgac ttgcacttct agggattgga gataattgtt ttgctctccg
    26281 tcagttttga caggaattcc gtactcagac agggcgagga gaatctggtc attacgactg
    26341 cggctggagg tcagaagggc aatttcttta aaggcaacac ctttttcttg atgaagtttc
    26401 agaatctcct tgataactaa gcgcatttcg cctgttagtt tcgtttctgc ctgcccctct
    26461 tcttcctcac ctgtgtcgtc cttgtcatag aggagaaatt ctaccttgtt gtctggattg
    26521 ggagtcagtt tggtattggc aaaaacaagc tggtgcatgt tatcatagtt gatttcgccg
    26581 acctcttgat ccataagacc ttcaaaaaca tcattggttg ctgatagcac ttctgaacta
    26641 ctacggaaat tttctttaag caaaatcagc ttgccttcgt gtggattttt cgcatagcgt
    26701 tgaaattttt cattgaaaat ctgcgggtct gcctgacgga aacgatagat ggactgcttg
    26761 atatctccca ccataaagcg attgtgccca ttggacaaca attccagcat ccgttcttga
    26821 atatggttgg tatcctgata ctcatcgacc atgacttcgt ggaaacgctc ctgataagct
    26881 tcacggactt gcgggaattt ctctaaaatc tcaatggtgt aatggctgat atcagcgaat
    26941 tcaaaggcat tttcctgacg tttacgctga cgataagcct ccacaaaatc gctcataaag
    27001 gtttggaagg ttttagctag tttccaagtg tctccatgat aacgttcttg atagtcgaga
    27061 atggttatct ggtctgataa ttgtcctagt ttagcaaact gggtctttct ctcttcgttg
    27121 taggcatcag ccaggggctt caaatcagcc ttacgactgg cattagtaag agctcgaccg
    27181 tttttctcct tagagatggc gacaacacgc gcaagcactg cctgataagc ctgactatcg
    27241 gactcctgat ttagggagcc aatttcatcc agaattaact gaacattttc taaataggca
    27301 gcctttgcaa actccttggc atcgttatcc agatggtaac ggaaaaagct ttccaaatcc
    27361 caaagggctt gtttgatttg ctcagtcagt ttttcttttt cactggtaaa atcagctttc
    27421 tcaaagcctt tgaggaaaga ttcactcagc cacttttgag gattactggt ggattggagg
    27481 aagtcataga ttttatagac ctgctggcgc agaccccgtt cgtccttgcc atgcccagca
    27541 aagtttttca gcaaatgact aaaggtctct ttctgtttac cttggtaatg cgcttcaaag
    27601 acctcatgaa agacttcgtt ttcgagaaga agttgctcgc tttggttttg taaaatacgg
    27661 aaattaggtg caatatcaag cagataacca tgtttgccaa ggaatttttg tgtgaaagaa
    27721 tccatggttc cgatggcagc gttgggtagg tctgccaact ggcgacccaa gtgttgtttg
    27781 aggtcgacat catctgtttc ttggattttc ttgctgattt ttttctctaa acgttcttta
    27841 agttcagttg cagccttgac ggtaaaggtt gagataaaga gttgagaaat ttcgacacca
    27901 cgcgccaatt ggtccagaat gcgctctgcc atgacaaagg tctttccaga accagccgat
    27961 gctgagacca ggatattctg accagaagtg tagatagctt cgatttgctc ggcagttttc
    28021 ttctgttcct tgctcgaatt tgcttctgct tcttgcagtt tttgaatctc ctcctcactt
    28081 aaaaagggaa taagcttcat cgattcaact cctctcttat tttttcaagc caagcttgct
    28141 tgagtttttc tccgaccaga cgcttgccat cagctaggtc caacttttct aggaaacggg
    28201 cttggcccag atggtaattg gcttcaaagc ctgtaatagc ctgatgttgc tggacgtatg
    28261 gggcaatgct tctgccattt tcagtataag gattgatggc gaaccggcct gctaaaatct
    28321 tctcagcagc tttcttgtaa agataggcat tgtagtccag taggagctga aattcctcat
    28381 ctgtcagttg attagccttg tttttgttat aaaattcgcc taaataactg ctttcttttt
    28441 ccaagaagag cccttggtat ttcatagatt tgctggcttc taccactgct cctgccagac
    28501 tttttaccgc tatcagagat tggacaggtt cagccatttc caagtacatg gcgccgaaaa
    28561 agttctgctc cccttctctt tttagggcag caagataggt tggtaactga gaattgagcc
    28621 cattaaagaa atgaggaaac tggaactgag tcagactgga tttgtagtct actactccta
    28681 tcgctccatt agctttcaaa cggtcaatcc ggtccacctt gcctcgtaca aagacactgc
    28741 gtccattgtc taattgaata aaggcttggt cttttccacc aaaatttgct tcttctttga
    28801 tggtttcgat ggctggattg tgtcggagaa tatgtccagt tgtccgtgca acatcaagca
    28861 aaacttcctt ggtaaactgg gcttccaaac tttcttgata aatagcttca aattcgcgtt
    28921 cttgactggt ttcttgaata gcttgttcta gacgttggtc aaaggaatct tcattaggca
    28981 actgcaaggc gcgttcaaag atacgatgca agaaattccc gtgactacgg gcatcaggac
    29041 gcaaacgtaa ttcctcctgc aagcctaaaa cgtagcgtag gaaataactg tattcattgc
    29101 gataaaactc tgtcaaaccc gacgtagaca ggtaaaactc ctgtttggca ggatagagag
    29161 cttgcaaggt gtccttggct aaggtcttgc tgcttggact ggttgggatg gctggatttt
    29221 ccagaccttg cagatctagt tttttaccta tgacacgcga cagaaccttg acaaaagtca
    29281 aatcttgctc agtatcgctc atctcaccct gctggtgata ggcaaccaga ctagacaaaa
    29341 gactgtgata ggaccccata tcctccttag acagtccttt gtgattcatc ctcttctctc
    29401 tccgcctaaa tccaaaatgg atcaactctt gaagataggc agattcctta ctttcacttt
    29461 cgttaaaaag gcttggagcc gacaagaaca actgcttacg agcagaattg accaaggaaa
    29521 gcatagtgta gcgatttttc ttgagatttt cactgctggc aatcagtaat tgaacgcctt
    29581 cttcggtcgt ttggtttagg ttttgccttt cttcatctgt cagaagactg gtgttttgag
    29641 aaatttttgg taaattgtcc tgagttagtc caatagcata gacaaagtca gcagtcaatg
    29701 gtgcaatcaa atcgtaactc tgcaccagaa cagtgtccac tgttgctgga atggtacggt
    29761 attgggacaa actcattcca gaatggagca aggctaggaa gtcttccaga ctaacctgtg
    29821 aaccagcaaa aacagtcgca aattgttcta aaacatggca gaaagccttc caaacttcgg
    29881 cttgtctttc ctgttctaca gcttccaaag tggttgtcaa atcttgtaac tgcttggtca
    29941 cagctccttc ttttagaaag acactccatt tttgtaggag gttttcagcc ttttgttttc
    30001 ggctggcaaa gagggtttca agaggtgcta aaattctcag gcggaggaca ttcaaacgct
    30061 caagattaaa ttttccatgg tgggatttgg tgaagatttg ctgaaaggct ggcaagccat
    30121 tgataccaag atagcggata tattgctcaa aagcatcaat atcagactga ctgaggtcag
    30181 tatacaagtc agttctaaga agattaatca aatcctcctg acgaaaacgg taacgtttta
    30241 aagctaaaat agactcgaca aactgagtca agggatgatg agccatggct tcgcttctac
    30301 caagataaaa aggaatctga tactggtcaa aaatggtttt gagagataac tggtaagaag
    30361 ctacatcccc caagagaata cgaaaatgct tgtatctcag gtctgagttc tcatgtaatt
    30421 tctgacgaat actacgggct actagctcca actcctcctt ttgcgtcaaa caagaccaga
    30481 tttgtaaatt ttcacggtct ttctcatcga catccaaagc gagttctgaa aagtcataag
    30541 aagactccaa caaacgagag gccttgtcaa aactatccat cttctcatga gtttgagaac
    30601 agtcctgagc aggcgtttgg tatttagaag ccagatgatg gagaaatttt acgctggctt
    30661 ggtagagatt gccctcgcta aaaggactgg tataggcttt cttactagca taagccccga
    30721 taacaatctc aacacctttg ccgtgaagta agtccacaac ccgctcttcc tcagcagaaa
    30781 aacgagtaaa gccgtcaatg accaaggcga tttgattaaa atcactactt accttgtcat
    30841 tctcaatagc ctcaatcaaa tgggacaact gacttccctg ggctaactga ccttgattaa
    30901 gataggctgt tactttctca aaaatcaaga gtaaatccgc cctcttatcc tcatctgtta
    30961 aattctccaa gtccaaaaaa ctcatctgag atttggtcat ctcatggtaa agctcaatta
    31021 actgctggat caattgagga tcctgcttaa tagcgccata aacacgcaag tccttgggat
    31081 cgagttcggc aaggcatttg taaaaggcca acccaagacc gatatcatca agagtagttt
    31141 tagctggtaa atcattcaag accagatagc gagccatttg agcaaagcgc gtgacggtaa
    31201 tcgaaaaaga agcctgctgg gacaagtatt ccagcacggc gcgttccttt tcaaaagaaa
    31261 gagagttggg ggcaatgtag aagacccgct tgccagctgc aactagctct tctgcctttc
    31321 ttgttagaat ttctgtcaaa gaagtccgaa tatcagtata aagtaatttc atctcagcct
    31381 cgttggaatt tttcatcacc ctatattata ccatgattat cctcgtaaat ctgttaaaat
    31441 atttaggcca tcctttcttt tcttcatcat ctgctaaatc ttaaatactt agctttactt
    31501 gtattagata gaataagtct ggctactgaa aatcacataa taaaaaagcc tcggtaacaa
    31561 ggctttgagt tttatgattg tttcttatta ggtacggaat acacttcaat gtgttgtccc
    31621 agtatcttaa tgtcgactgg tagattgtct gatttatcac catcaacatc ggactctaat
    31681 tcgatatcag aagaagtttt aatattacgt gcctttatat attcaatatt cttgatagaa
    31741 tgattgaact atagcaaatt gaaactataa tagtacaccg tggatgctaa aatatttcta
    31801 gaaattaatt tgatttccct aatcaagctg ttcgtatctt atttcaatct actatagtaa
    31861 aatgaaccaa aaatagtaca taatgtggta taatcgtctt atgggatatt caatagattt
    31921 tcgtaaaaaa gttctctctt attgtgagcg aacaggtagt ataacagaag catcacacgt
    31981 tttccaaatc tcacgtaata ccatttatgg ctggttaaag ctaaaagaga aaacaggaga
    32041 gctaaaccac caagtaaaag gaacaaaacc aagaaaaatt gatagagata gacttaaaaa
    32101 ctatcttact gacaatccag acacttattt gactgaaata gcttctgaat ttggctgtca
    32161 tccaactacc atccactatg cgctcaaagt tatgggctac actcgaaaaa aaagaaccac
    32221 acctactatg aacaagaccc agaaaaagta gccttatttc ttaagaattt taatagttta
    32281 aagcacctag cacctgttta gattgacgaa acaggattcg atacttattt ttatcgagaa
    32341 tatggtcgct cattaaaaga tcagttaata agaggcaaag tatctggaag aagatatcag
    32401 aggatttctt tggttgcagg ggctaacaaa tggtgaatta atcgttccaa tgacttacga
    32461 agagacgatg acgagcgact tttttgaagc ttggtttcag aattttctct taccaacatt
    32521 aaccacacca tcggttatta tggtaaaatg aaataagaat aggacaaatc gatcaggata
    32581 gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcca
    32641 ctatattatg gataatgcaa gattccatag aatggggaag ctagaactct tgtgtgaaga
    32701 gtttgggcat aaacttttac ctcttcctcc ctactcacct gagtacaatc ctattgagaa
    32761 aacatgggct catatcaaaa agcacctcaa aaaggtatta ccaagttgca atacctttta
    32821 cgaggctctt ttgtcttgtt cttgtttcaa ttgactatat aaattgtcta agcgaaacaa
    32881 ccgataagaa ttggcacaaa agcgaccgta tttttgttac caatacagga aaaccagttc
    32941 atagttccat cttgagcaag tcgtctctcc agcgagcaaa cgaacgcctt aaaaaaccaa
    33001 ttcccaaaca tctgtcccct cacatcttca gacacaccac tattagcatc ttatcagaaa
    33061 ataaaattcc tttaaaaaca atcacggaca gggttggtca ttccgactct gaagtcacta
    33121 cttccatcta cacctacgtc acaaagaaca tgaaagatga agcaatcaat gtactggata
    33181 aagttatgaa aaagattttt taaaaagttt tgcccctttt ttgtcctcta aatacaaaaa
    33241 tagcccttcg gataaaatcc gaggggctag aaacgttgtt aaatcaacga ccgaactttt
    33301 gagtttcaag gttcgggata aaatagttca ctgaactatt ttatttttta aggttgtaga
    33361 atgatttcaa tccacgatat tcagctactt caccaagttg gtcttcgata cgaagcaatt
    33421 ggttgtattt agcgatgcgg tctgtacgtg aaagtgaacc agtcttgatt tgtcctgcgt
    33481 tagttgcaac tgcgatatca gcgattgttg aatcttcagt ttcacctgaa cggtgtgata
    33541 caacagcagt gtaaccagct tctttagcca tttcgatagc ttcaaaagtt tcagtaagag
    33601 taccgatttg gttaactttg ataaggattg agttagcagc accttcttgg ataccacgtg
    33661 caaggtagtc agtgtttgtt acgaagaagt cgtcaccaac aagttgtact ttcttaccaa
    33721 gacgttcagt aagagctttc caaccatccc agtcgttttc atccatacca tcttcaatag
    33781 tgatgattgg gtatttatta accaattctt caaggtagtc gatttgttct gcagatgtac
    33841 gaacagcagc accttcacct tcaaatttag tgtagtcgta aactttacgt tctttatcgt
    33901 agaattctga tgaagcacag tcaaatccga taaatacgtc tttacctggt acatatccag
    33961 cagcttcaat cgcagcaagg atagtttcaa caccatcttc agttccttcg aaacgaggag
    34021 cgaatccacc ttcgtcacct acggcagttt ccaaaccacg tgatttaagg attttcttaa
    34081 gagcgtggaa gatttcagca ccgtaacgaa gggcttcttt aaatgttggc gcaccaactg
    34141 gcaagatcat gaactcttgg aaagcgattg gagcgtcaga gtgagaacca ccgttgatga
    34201 tgttcatcat tggagttgga agaactttag tgttgaatcc accaaggtag ctgtaaagtg
    34261 ggatttcaag gtagtcagca gcagcacgag ctacagcgat agacacaccg aggattgcat
    34321 tcgcacccaa tttacctttg ttaggagtac cgtcaagtgc gatcatagca cggtcaatag
    34381 cttgttgatc acgtacatcg tagccaatga tagcttcagc aatgatgttg tttacgttgt
    34441 caacagcttt ttgtgtacca agaccaccgt aacgagattt gtcaccgtcg cgaagttcaa
    34501 ctgcttcgtg ttcaccagta gaagctcctg atggaaccat accacgtccg aaagcacctg
    34561 attcagtgta aacttctact tcaagtgttg ggttaccgcg tgagtctagg acttcgcgag
    34621 cgtaaacatc agtaataatt gacatttttt actctcctta tgagttaaat tttttacacc
    34681 tctataatac cttaaaaccc ctcctttttc aagaaaaaac gttatctttg tgcaactttt
    34741 ccttaacttt ataaagtaat cgctttcttt tgtctgtttt attctaactt ttatgatata
    34801 ctgttttcat gacagattta tcaaaacaat tacttgaaaa agctcatggt gggttaaaaa
    34861 taaatccgga tgagcaaaga cgctatcttg gtacttttga ggaaagagtt cttggatatg
    34921 tagatattga cacagcaaat agccctcagt tagaaaaagg ctttttattt attttagaaa
    34981 accttcagga aaaagcagag ccactatttg tgaagatttc accaactatc gaatttgata
    35041 agcaagtttt ctacttaaaa gaagcaaaag aaactgatag tcaagccacc atagtatctg
    35101 aagagcatat tacttctcct tttggcctgg ttattcatag caatgcacca gttcaagtag
    35161 aagaaaaaga ccttcgactt gcttttccaa aactttggga agttaaaaag gaagaaccag
    35221 ccaaaacatc cttatggaag aaatggttta gctaaatctt gcacatattt aataagtgcc
    35281 caatattggc agccgtgcgc tccagataga gactggcatt tttcaaacta tcttctaaag
    35341 gttcactttt ctccaaaata gaaaagacag cttggatatt ttcaaatggt aggggaggta
    35401 aatcttcagc aagactaccg caaatagcaa taacaggaac tccaacaggg gttctttttg
    35461 caacacctat aggcgctttc ccagcaaagc tttgactatc aagccttcct tctccaacaa
    35521 caaccaagtc agcatctgaa actttcttat taaagttgat taagtccaag caggtatcaa
    35581 ttccagacac tatacttgcc tgagcaaagg cacacaaacc accagcaagg cctccacctg
    35641 atcctgctcc tttaatttct aatgttgcag gtgagaattt ttcataaaaa tcttggatcg
    35701 cctgatctac gactgcaaac atagtcggat gtagaccttt ttgattacca aaagtgtaag
    35761 tcgcaccttg atgaccacat aagggactca cgacatctgc tagaatatga atttgaacac
    35821 cttcaggaat tttatagcaa ttttctgttg aaacagaagc taagtttaat aaggattgac
    35881 cggaagcagg caagacattt ccatccctat cataaaattg ataacctaaa ccagcagcaa
    35941 tccccagtcc tccatcatta ctggccgtgc caccaacacc gatataaata tctttaatcc
    36001 ctttagaaat gagatggaga atcaactctc caataccaca agtttggatt tgaagtggat
    36061 ttcgcttctc tagcggaatt tttccaagac caaccaagtc agctacttca aatagtgcca
    36121 gttccccttt ttgaaaatag cgcatggctt ctttttgtcc aaaagggtct gtcacttgga
    36181 tccatttttc ttttaggtca agagaatgtc ggatagcatc tacagtacct tctcccccat
    36241 caccaacagg gcagaggaga tattctacat ctgctatcga ttgttggaag cctctgctat
    36301 cgattgttgg aagcctcttt ttattgcttc agctacctgt tgagctgtca agctttcctt
    36361 aaacgaatcc ggtgcaatta caatcttcat attttccctc attctaaacg gtcaatcaaa
    36421 ggaagaactt ctaaaaaatc cctcttgtca acatgatgtg gtatttcttt tttgagcact
    36481 tctttggcac aaaaggcgat tcctaactcc gccgacttca acattaatag attattaacc
    36541 ccatcaccga ttgccaccgt tctttcttta gaaagtttta gtttctttct ccatttttcc
    36601 agagtctctt tttt
//
LOCUS       DAVDHZ010000021        34697 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000021 DAVDHZ010000000
VERSION     DAVDHZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34697
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.021"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(139..2136)
                     /gene="metG"
                     /locus_tag="VUR46_001184"
     CDS             complement(139..2136)
                     /gene="metG"
                     /locus_tag="VUR46_001184"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET5456614.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPEGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEVVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2260..3519)
                     /locus_tag="VUR46_001185"
     CDS             complement(2260..3519)
                     /locus_tag="VUR46_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456615.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3521..4222)
                     /locus_tag="VUR46_001186"
     CDS             complement(3521..4222)
                     /locus_tag="VUR46_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456616.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4206..5405)
                     /locus_tag="VUR46_001187"
     CDS             complement(4206..5405)
                     /locus_tag="VUR46_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET5456617.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5691..7037
                     /gene="gor"
                     /locus_tag="VUR46_001188"
     CDS             5691..7037
                     /gene="gor"
                     /locus_tag="VUR46_001188"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET5456618.1"
                     /translation="MKEYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTVKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            7234..7770
                     /locus_tag="VUR46_001189"
     CDS             7234..7770
                     /locus_tag="VUR46_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET5456619.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7821..7907
                     /locus_tag="VUR46_001190"
                     /pseudo
     CDS             7821..7907
                     /locus_tag="VUR46_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7976..8191)
                     /locus_tag="VUR46_001191"
     CDS             complement(7976..8191)
                     /locus_tag="VUR46_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET5456620.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8289..8609
                     /locus_tag="VUR46_001192"
     CDS             8289..8609
                     /locus_tag="VUR46_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456621.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8639..8977)
                     /locus_tag="VUR46_001193"
     CDS             complement(8639..8977)
                     /locus_tag="VUR46_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456622.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVECATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8989..9708)
                     /gene="trmD"
                     /locus_tag="VUR46_001194"
     CDS             complement(8989..9708)
                     /gene="trmD"
                     /locus_tag="VUR46_001194"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET5456623.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9698..10216)
                     /gene="rimM"
                     /locus_tag="VUR46_001195"
     CDS             complement(9698..10216)
                     /gene="rimM"
                     /locus_tag="VUR46_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET5456624.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10262..11035)
                     /locus_tag="VUR46_001196"
     CDS             complement(10262..11035)
                     /locus_tag="VUR46_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5456625.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAII"
     gene            complement(11612..11851)
                     /locus_tag="VUR46_001197"
     CDS             complement(11612..11851)
                     /locus_tag="VUR46_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET5456626.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(11871..12143)
                     /gene="rpsP"
                     /locus_tag="VUR46_001198"
     CDS             complement(11871..12143)
                     /gene="rpsP"
                     /locus_tag="VUR46_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET5456627.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            12313..12522
                     /locus_tag="VUR46_001199"
     CDS             12313..12522
                     /locus_tag="VUR46_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456628.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            13001..13222
                     /locus_tag="VUR46_001200"
     CDS             13001..13222
                     /locus_tag="VUR46_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456629.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            13305..14108
                     /locus_tag="VUR46_001201"
     CDS             13305..14108
                     /locus_tag="VUR46_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET5456630.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITVDSIEVVKDYDFKS"
     gene            complement(14164..15705)
                     /locus_tag="VUR46_001202"
     CDS             complement(14164..15705)
                     /locus_tag="VUR46_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5456631.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERHQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKCALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(15707..16189)
                     /locus_tag="VUR46_001203"
     CDS             complement(15707..16189)
                     /locus_tag="VUR46_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET5456632.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(16189..17274)
                     /gene="rlmN"
                     /locus_tag="VUR46_001204"
     CDS             complement(16189..17274)
                     /gene="rlmN"
                     /locus_tag="VUR46_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET5456633.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(17295..17825)
                     /locus_tag="VUR46_001205"
     CDS             complement(17295..17825)
                     /locus_tag="VUR46_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET5456634.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(17981..18586)
                     /locus_tag="VUR46_001206"
     CDS             complement(17981..18586)
                     /locus_tag="VUR46_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET5456635.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(18759..19796)
                     /locus_tag="VUR46_001207"
     CDS             complement(18759..19796)
                     /locus_tag="VUR46_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET5456636.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(19830..20765)
                     /locus_tag="VUR46_001208"
     CDS             complement(19830..20765)
                     /locus_tag="VUR46_001208"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET5456637.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(21318..22508)
                     /locus_tag="VUR46_001209"
     CDS             complement(21318..22508)
                     /locus_tag="VUR46_001209"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET5456638.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(22723..24066)
                     /locus_tag="VUR46_001210"
     CDS             complement(22723..24066)
                     /locus_tag="VUR46_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5456639.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(24206..25021)
                     /locus_tag="VUR46_001211"
     CDS             complement(24206..25021)
                     /locus_tag="VUR46_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET5456640.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPL
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(25073..27253)
                     /locus_tag="VUR46_001212"
     CDS             complement(25073..27253)
                     /locus_tag="VUR46_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5456641.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(27539..28465)
                     /locus_tag="VUR46_001213"
     CDS             complement(27539..28465)
                     /locus_tag="VUR46_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456642.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(28458..29150)
                     /gene="ftsE"
                     /locus_tag="VUR46_001214"
     CDS             complement(28458..29150)
                     /gene="ftsE"
                     /locus_tag="VUR46_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET5456643.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(29168..30263)
                     /gene="prfB"
                     /locus_tag="VUR46_001215"
     CDS             complement(join(29168..30190,30192..30263))
                     /gene="prfB"
                     /locus_tag="VUR46_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET5456644.1"
                     /translation="MDISVIRQQIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(30371..31027)
                     /locus_tag="VUR46_001216"
     CDS             complement(30371..31027)
                     /locus_tag="VUR46_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5456645.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(31335..32045)
                     /locus_tag="VUR46_001217"
     CDS             complement(31335..32045)
                     /locus_tag="VUR46_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456646.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(32045..32809)
                     /locus_tag="VUR46_001218"
     CDS             complement(32045..32809)
                     /locus_tag="VUR46_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456647.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLDYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(32809..33765)
                     /locus_tag="VUR46_001219"
     CDS             complement(32809..33765)
                     /locus_tag="VUR46_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET5456648.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(33769..34638)
                     /locus_tag="VUR46_001220"
     CDS             complement(33769..34638)
                     /locus_tag="VUR46_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET5456649.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
BASE COUNT        10269 a         7613 c         6301 g        10514 t
ORIGIN      
        1 agctgacttc gtcagttcta tctacaacct caaagcagtg ctttgatcaa cccgcggcta
       61 gcttcctagt ttgctctttg attttcattg agtataaata aaaaaaacag aactagtctg
      121 aactagtcct atctactttt acccaatcac acttccattt ggtacagctg gatcaactgt
      181 gagaagggtt aatttgccat catgttcagc tgagagaatc ataccctggc tgacatattt
      241 tttcatcatt ttacgtggtt tgaggttagc aacgatttga actttcttgc cgaccaattc
      301 ttgttcattt ggatagtatt ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc
      361 agcatccaag cggaattgaa gcaacttatc tgaaccttcc actttagaca cttctttgac
      421 ttctgcgaca cggatttcaa ccttgtcaaa gtcttcaaac ttgatttcat ccttgtttag
      481 tttgagctca acttcgtccg gattccattc tttttcgact gctggtttat tgccttccat
      541 ttgttccttg atataggcga tttcttcttc catatttaga cgtggaaaga taggtgttcc
      601 tttggcaact acagtcacat ctgctgggaa gtcagccaaa ctcaagtttt caagactaga
      661 aacttcttcc aaaccaagtt gagtcaaaac tgcacgacta gtttccatca taaatggttc
      721 aatcaagtga gcaactacac gaatgctggc tgccaagtgg ctcatgacac ttgccaattg
      781 gtcacgaaga gcttcatcct tggccaagac ccatggtgcg gtctcatcga tgtatttatt
      841 ggtacgagag atcagagtcc agactgcttc aagcgcacgt ggatagtcaa ctacttccat
      901 gtgtgtatgg aagtctgcga ttgattgttc tgcaacctca gcaagaacat gatcaaattc
      961 agtcacacct tctacatagg cagggatttg tccatcaaag tacttattaa tcatggaaac
     1021 cgtacggtta aggaggttcc caaggtcatt agccaattca tagttgatac ggccgacata
     1081 gtcttcagga gtaaaggttc cgtctgaacc aactggaagg ttacgcatga ggtagtaacg
     1141 aagtggatct agtccataac gctctaccaa catttcaggg taaacgacat tcccttttga
     1201 cttagacatt tttccgtctt tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa
     1261 tttaacatcc aacatcataa gaaggattgg ccagtagata gagtggaagc gaaggatgtc
     1321 ttttcctacc atatggaaga ctgttccatt ccagaacttg tcaaagttac catgttcgtc
     1381 ttgagcgtag ccaagagctg tcgcatagtt aagaagggca tcaatccaaa cgtagacaac
     1441 gtgttttgga tttgatggga caggcactcc ccatgtaaag gttgtacgag ataccgccaa
     1501 atcttccaaa cctggctcga tgaagttgcg tagcatttca ttaaggcgac cctctggcgt
     1561 gataaattca ggatgagctt tgaaaaattc gaccaaacgg tcttggtatt tgctaaggcg
     1621 aaggaagtat gattcttcag aaacccattc aacctcatga cctgatggag caataccacc
     1681 agtcacattt ccagcttcat cacggaaaac ttctgccagc tggctttctg taaagaattc
     1741 ttcgtctgat actgaatacc aaccagagta ttcacccaag tagatatcat cttgagcaag
     1801 taagcgttca aagacctgtg cgacaacttt ttcatggtag tcatcggttg tacggataaa
     1861 tttatcgtat gagatatcta gtaattgcca gagttcttta actccaaccg ccattccatc
     1921 aacataggct tgaggtgtaa taccagcttc ttccgctttc tgctggattt tctgaccatg
     1981 ttcatcaaga cctgtcagat aaaatacatc gtagcccatc aggcgtttgt aacgtgctag
     2041 gacatcacat gcgatagttg tgtaggcaga accgatatga agtttcccag atggatagta
     2101 aatcggcgtt gtaatataaa aatttttttc agacataatt tttcctttcc aggcaaatga
     2161 aacctgtttt tctaacactt cattatatca catttttaat gaatttcgat agggaaatcc
     2221 atacaaaaac aagatagacg agtgtccatc ttgttgatct cattcataac gaagggcttc
     2281 aattggatca agtttcgatg ccttgttggc tggcaagact ccaaaaatca taccaacact
     2341 agccgaaact gcaagactaa atagggcaac tgggattgat actccaactt ctataccttc
     2401 tattaaacct tgcagtaaca aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc
     2461 aattaagcca cctaacaagg tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt
     2521 ggcacgtgtt gcacccaaag ccttacgaag accaatctca cgagtgcgct ctgtcaccga
     2581 aaccagcatg atgttcatga caccagttcc tccaacaaag agagaaatcc ctgcgatgga
     2641 actaataatc gtcgtcataa aactaaacga ttgttgaatt tctgcaaata caacggactc
     2701 atctgccacc tggtattctc cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag
     2761 ttctggaccc agagttgggg ttaaactggt atcattcact cgaaagacaa tattagctat
     2821 ttcatctaca ttaaaattcg cagcaaggga gatattggta gtaataggca agccaccaaa
     2881 cccatatatt tttgatcttt tagcctccgg actagtataa accccaatga cccggtaact
     2941 aaatccattg acttctacaa ccttgttaat agcctcttga ggagattcaa ataaactaat
     3001 ggacaattcc tcatctagca aaatgacact tgcaaactct ttgaaatctt gctctctcag
     3061 actacgacct gcaataattt cattcttaac agcgtccatg taagttctgt ttccacctgt
     3121 caaattagca ttctcaacct ttttatcttg ataggtcaag atggcattcg ttgaattggt
     3181 tacatagtaa ctatccactc ccttcagttt agctgcctct tggacccagg attcttgcgg
     3241 ttttggcggt tcaacaggaa cttcctcttc ctttccagaa accgtaaaag ctgattgttt
     3301 ctgagtaaaa gacccgtctt tacttttttt aggagagaaa aagacgctaa tatttttctg
     3361 agatttagtc atatctttat tgacttgacg agatagggaa tcacccaaag ccataatcac
     3421 aacaactgat gaaacaccga taataatccc aatcatagta agcaaagaac gcatcttgtg
     3481 agccatgata gatgaaaagg caaatttcag attctgcatc ttagttttcc tcctttccta
     3541 actgagcact gtcagacgaa atgaccccat cccgaatgac aatctgacgt ttggcatagg
     3601 cagcaatctc aggctcatgc gttaccatga taatggtttt tccttcttta ttcaaatcaa
     3661 ccaataattg cataatttgg ttacctgttt tggtatccaa ggctcctgtc ggttcatccg
     3721 ctaggataat agaaggattg tttaccaagg cacgcgcaat ggctacacgt tgcttttgac
     3781 caccagataa ttctgaaggt aaatggtgac tacgttctgt caattcaacc ttgtctaaat
     3841 attcctcagc caacttgcga cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt
     3901 ctacattttg cagagcattg agcttcgata gaagaaagaa ctgctgaaag acaaaaccga
     3961 tttgttggtt acggacctta gctagttgtt tttcaccaag cccagccact tcttgacctt
     4021 caagataata ttctccactg gttggtgtat ccaacatgcc aatcgtattc atcagagtgg
     4081 acttaccaga cccagatggt cccatgatgg ctacaaattc accctcattc acttctagat
     4141 tgatattttt gagaacctgc agttcttggt caccattacg gtaacttctg aagatatttt
     4201 ttagactaat tagttgcttc atcagccttc acctcttttc cttcttccaa ggaagatgtt
     4261 ggattactga tgaccttagc accgttcgtt aaaccagaag tgatttcttg attttctgcg
     4321 tcagcatttc ccaatgaaac ctcaactttt ttagcctttt gttgttcatc cacaatccag
     4381 acataatttt tactatcatc cattactaga ctgctaacag gaacaagaat agccttagtt
     4441 ttgcttttaa cctcaatgtt gacagaaaaa ccttgtttca aatcaccaac ctcgcctgtc
     4501 acatcaatag tataagggta tttagaacct gtattattcc cggctgctgg actagctgct
     4561 tcaccattgt ttttaggata gtcagaaata tagcttaatt tcccagtcca ttttttatca
     4621 ggatacactt tagaagtaaa gcttacttct tgacctacag aaaggttggc tagattgtac
     4681 tcagacaatt ctcccttgac ttgtaaattt tcattgctga caatatgaac cataacttgg
     4741 ctcgcccctg ttggagattt agaaacattg ctattgactt cgactacagt tccctctagg
     4801 gtactgagaa cagttgttgc atccaattga ctttgagcct tgcttaattg cgccgcagca
     4861 tctgcacgcg catcacgggc atcacccaat tgagcgtcaa tagaagcaac agaatttcca
     4921 gccactggag ttgggctttg caccgttgca tcttctcctc ctactggcgc tggtaactgt
     4981 ggagccggag ctgaagcggc ttcatttcgt gcttgattga gttcattgat atgacgatct
     5041 gccttagcta ctgctcgact agctgaatca taggccgcct gcgcttctga actactgtac
     5101 ttgactaaag cctgcccttc gctgacctta tcgcccacag aaacaaggat ttcatctaaa
     5161 tcacccttac tagcatcaaa ataaacatat tgttcatttt ttgctgttac tgtccctgac
     5221 aataaaacag aggatgccac gcttccttcc ttggcaacaa caagatgagt aggctcatct
     5281 tttagagcag tctgagaagg ttgtctaaag agtaaaatcc ccccggcacc caatacaact
     5341 acactcgcag caccgattgc tgcatacagt tgccactttt tagctttacc attctttttc
     5401 ttcataatga aactcctttt cttgtttaca atactttgct attataccaa atttccctcc
     5461 agcaaacaat gcagttcaga tggaaataat ggcagttcag gattaaacaa tcgttcggaa
     5521 ttttgctttt ctattgtact agatatataa tacactatct tgacttattt ggcaagcttt
     5581 tttgcaattt tttgtgcgta gcagattttt gcaatcaaat caaaaaaaga ataaaatata
     5641 actatcaaaa aagacgctct actatttaaa agattacaaa ggagttttca atgaaagaat
     5701 atgatatcat tgctatcggt ggaggtagcg gaggaatcgc taccatgaac cgtgctggtg
     5761 aacatggagc caaagcagcc gttattgagg aaaagaaatt aggtggaacc tgtgtcaacg
     5821 tcggttgtgt tcctaaaaaa atcatgtggt acggggcgca aatcgctgag actttccatc
     5881 aatttggaga agactacggc tttaagacta ctgatcttaa ctttgacttt gcaaccctac
     5941 gtcgcaatcg tgaagcctac attgatcgcg ctcgttcttc ttatgatggt agttttaaac
     6001 gcaacggtgt agacttgatt gaaggtcatg ctgaatttgt agattctcat actgtaagcg
     6061 taaatggtga actgattcgt gctaaacata tcgtgattgc tacaggtgcc catccaagta
     6121 ttcctaatat tcctggtgct gagctaggtg gctcttctga tgatgtattt gcctgggaag
     6181 aacttccaga gtcagttgcc attctaggcg ctggttatat cgccgttgaa ttagctggcg
     6241 tactccacac ttttggtgtc aagacagatc tctttgttcg ccgcgatcgt cctttacgtg
     6301 gttttgattc ctacatcgtt gaaggtttgg tcaaggaaat ggaaagaata aacttgccac
     6361 ttcatactca caaagtccct gccaagttag aaaaaactgc taaaggcatt accattcatt
     6421 tcgaggatgg taccagtcac acagctagcc aagttatctg ggctacaggt cgccgtccaa
     6481 acgttaagag cttgcaactt gaaaaagctg gagtgactct gaatgaacgt ggctttatcc
     6541 aagtagatga ataccaaaat actgttgttg agggaatcta tgctctaggt gatgtaacag
     6601 gtgaaaaaga actgactcca gttgcaatca aggctgggcg taccctatct gaacgtctct
     6661 ttaacggaaa aactactgta aaaatggatt actcaactat tccaactgtt gtcttttcac
     6721 accctgctat cggaactgtt ggtttgacag aagagcaagc tattaaagaa tacggtcaag
     6781 accaaatcaa ggtttataaa tcaagctttg catctatgta ctctgcttgc actcgcaacc
     6841 gtcaagaatc ccgtttcaaa ctcataacag ctggttcaga agaaaaagtt gtcggacttc
     6901 atggaattgg ctacggcgtt gatgaaatga ttcagggatt tgccgttgct atcaaaatgg
     6961 gagcaaccaa ggctgacttt gatgcaactg tggcaattca cccaactgca tctgaagaat
     7021 ttgtaaccat gcgttaatcg aaacaaaaga agctgatata aatatgtctg cttctttttt
     7081 aatgattttc gaatcaacaa aaaaattatc caacttgact agtcacgaaa atcggctgtt
     7141 acagtttttg ttaccttgtt tttaaaaaat ggttgacatc gactcctata tgagtataat
     7201 agttactata cattagaaaa gaggttaact attttgaaaa aagctcacgt ttatgctatc
     7261 cctgctattg gggctgctct cattgctgtt ttggcacaaa tcagtcttcc aattggacct
     7321 gttcccttca ctctgcaaaa ctttgcaatc ggcttgattg ctactgtctt tagaccgaga
     7381 gaggctgtac tttctgctgg actctatctt cttctaggtg ctatcggtct tcctgtcttt
     7441 gcaggaggtg gagctggttt tcaggcttta gttggcccta ctgcaggcta tctttggttt
     7501 tatctcgttt actctggact tacttcctct ctaaccaaca gcaagagtgg tgttgttaag
     7561 atttttcttg caaacctctt gggtgatgcc cttgtctttg tcggcgggat tctcagcttg
     7621 catttcctag ctggaatggc atttgaaaaa gctcttgttg tgggggttct tccctttatc
     7681 attccagacc ttggcaaact tctggctatt agttttatta gccgtcccct acttcaacgc
     7741 cttaaaaatc aggcttactt tactaactaa aaaaggatat cgagttatca tgactcaata
     7801 tccttttctt ttattttgaa aacttatact caatgaaaat caaagagcaa actaggaagc
     7861 tagccgcagg ctgctcaaaa cactgttttg aggttgtgga tgaaactgac gaagtcagta
     7921 accatacata cggcaaggca aagctgatgc ggtttgaaga gattttcgaa gagtattagt
     7981 tgcctttaaa ggcatccacc atcgtttgaa attcttcatt tgagagagta atccctttgc
     8041 ccattttagt atggtctgga ctccaagcac gaatatcaaa ctttgcaggg gcaccattaa
     8101 agctcacacg gttaatttcc ttggtccaac ctttttcgtt ttcagaaaga gtcaacaagt
     8161 gctcttcgat ttcaaatgta aattctgcca ttttcttctc cttttttagt ttcattagtt
     8221 tattcgtaaa atcttgtaga ttttaggaaa attttatata atattgatat aaaagaaggg
     8281 aggccaatat gagacataaa ttccagcaag ttctaaataa aatacatgat tttttaaatg
     8341 gatatgacca acctgaccag actgaaacca actcccttac agccactatt gaagaggcta
     8401 tccagaaaca aaccgctgtt caccttatct tatctgagac aagctttaca ggtgacatca
     8461 tcaaatatga tcagcaaggc cagcaaatta tcgtgaaaaa tttttccaaa aatgtgagcc
     8521 ggattatccg tataagcgat attcaacgcc tgcgatttgt cccctcaact gtccaaacag
     8581 cccaaaaaaa tagatttaag aaagagtgag atgtagttgc ttcatcccac tctttttctt
     8641 agcgaatttg ttcaaaatgt aaatgaactg cgatatgatc tccataacca cttctttcca
     8701 agtcacgttg taaacgatag gaaatatagt gttctgcaat ggtaatgtaa cctgcgccca
     8761 ataaacgatg ttcaaccata gattgaatca tactgatagt cgcacattcc accttggctt
     8821 cttgtaaatc caaaactacc ttcttagtga cttgagcaag attttgacgc aaatcatctg
     8881 tcaaaacata aacagtttgg gctgccttca agatggcttg gtaaatctta tctggattaa
     8941 attcagcaat ttcgccatta cgtttgatta cttgcatagg tttctccttt attctttgtt
     9001 ttctttgatt tctgccagca ttttttcttc ttctactgtc agttgataat gttcaagtaa
     9061 atctggtctg cgctcgtagg ttttctttaa actctcgtac aatcgccact gacgaatctt
     9121 ttcatggtgg ccactcatca atacatctgg cacgaccatg cctcgataat catagggacg
     9181 tgtgtactga ggatattcta aaagacccga agaaaaacta tcatcttggt ggctagactc
     9241 cttgccaatc acttctggaa tcaggcgaac tgtagcatca atcatggtca tagctgccaa
     9301 ttctccacca gtgaggacat agtcgcctag ggaaatctca tctgttacca aggtcttaat
     9361 gcgctcatca taaccctcat agtgcccaca gataaagatt agctcttcct cttgagccaa
     9421 atcttcagca taagcctgat caaactgctt tccagcagga tcgaggagaa taacgcgcgg
     9481 atttttcttt tcaatagcat caaaggaatc gaaaataggt tgtgctctga gcaacatacc
     9541 ctgaccgcct ccgtagggct catcatctac atgacgggcc ttttcagcat tttctcgaaa
     9601 attatgatac tggatatcca agagcccttt ttctcgagcc tttccaacga ttgagtgctc
     9661 cagtggagaa aacatctctg gaaagagggt taaaatatca atcttcatcg tctaaccctt
     9721 ctaagatttc cacatcgacc cgtttatttg gaatatcaac attgagaacc actggtggga
     9781 tataaggtaa aagcaaatca cgtttgcctt ttcgtttgac cacccagaca tcattagcac
     9841 ctggttgcag gatttccttg atggttccaa ccaagctatc accctcatag acttccaaac
     9901 cgataatctc gtgatagtaa aattcaccat cgtctaggtc attcaaatct tcctcagcga
     9961 ccttgagact atatcccttg tacttttcga tagtattgat atggtacata tctttgaatt
    10021 taataatgtc aaagttcttc tgtttacggt ggctagcgat ggtcactgtt tggacaaact
    10081 gatctttttc atcaaacaaa gccagctcag ctcctttttt aaaccgttct tctgcaaaat
    10141 ccgtcacaga caagactcgc atctcaccct gtaatccctg cgtattaacg attttcccaa
    10201 cattaaagta gttcatcttg tctcctgtaa tctccttttt tccatcttat tctgacaatt
    10261 ctcaaataat agccgcaatt ttttccgatt ctgaccattg taaataatgg tgattccctc
    10321 ctaaaatgag tttagtattg gaagtccaat attctgattc tctgtactct ttttctctat
    10381 aaggctgaca aaaaacaaat acaggaatat gagcttctat agatacatcc tcaaaatctt
    10441 cctcagtaat ctctccagat atctgaaatt ctggatcttg attttccaac tctaagcctt
    10501 tttcttgcat taattcccag atttttttat tcgtttcagg actaaatgtt gcttgagtta
    10561 agttcttaaa ataaagttca ggaccacact cgtcaatcag cctcatctgc tcttccattt
    10621 ctggataagg attttctgaa aaatcagcaa acatgacttt tttagttgtc ggttcaattg
    10681 ctactaaagt ctgacgctta attggtttct cgagtaattt gcaagctaaa attccactcc
    10741 aactatgtgc acaaagtata tattcagaaa ttcctaattc ttcaagtact tcataaaccg
    10801 catctgcaag attatctaga ttttttccag cttggtcatg aatcggactc ctacctgtgt
    10861 tcggaaaatc aattgtcaaa taaccaattg taggaggagg tttttcaagt ataagtgaaa
    10921 aattttcata acttggtagc aaacctgctc cgtttagaca aactagcact ttcttttgct
    10981 tttgataagt aacagagagg ctaccaattt ctgtagatac ttcaaacctc ttcataaaga
    11041 aatccactca ttctatataa tgaattatta aaaatcctta tcctttattt tatcacgttc
    11101 caaggatttt ctcaagttgg aggaaaggga caacatctct actttccctt caagaatcct
    11161 tccaaattat gtttatgttg gtaattaacg gctgcggttt tgtctttctc aaagacagtc
    11221 ttggtaaggt caatatgatt aatagctacg attgcgacgg tgtagtaaat gatatcagcc
    11281 agttctctgg caagttcctc gttcgaatcc tatcccttct tttcgaccag agcgcctatt
    11341 caaaacctcg gctacttctc cgacttcctc cactaacttc ataaagagac cttcatcagt
    11401 ccgagactgc tgttaatgtt cgagtaagta gtcttggaat tgcctaaacg ttcaatcttt
    11461 tatagtatat tgaaactaga atagtacacc tttacttcta aaacattgtt agaaatcgat
    11521 ttgactgtcc tgatcgattt gtcctgttat tatttctttt tactatatct tctattccac
    11581 acaaaaaagc gagacatccg tcccgccctt cttatttttc gtcaataacg attcttactt
    11641 ttttgtattc agttgggaca gagtagacaa tcgttcttat cgcagaaata gtgcgaccct
    11701 tacgaccgat tacacgaccc acatcgcttt gatcaagatt caaatgatat tccaaaaatt
    11761 ctggtgtatc ctcaatcttg atagttaagg catctggttg tgaaattaag ggtttcacaa
    11821 tcgcaataat gagattttca atcgtatcca tctgtcaacc tactttaaac ttattttgag
    11881 aatttagaat cgtggaattt tttcaatacg ccttcttttg aaaggatgtt acgtactgtg
    11941 tctgaaggtt gagctccatt agccaaccat gcaagaacgc ggtcttcttt caaagttact
    12001 tggttttcag caacaagtgg gttgtaagtt ccaactgttt cgatgaaacg tccgtcacgt
    12061 ggtgaacgtg aatctgctac gttgatacgg tagaaaggtt ttttcttaga acccatacga
    12121 gtcaaacgga ttttaactgc catttttaaa gtctcatttc tttaattttt tatttcggtg
    12181 aaatagctga gctatttagc acatgttcta ttatagcaga tttctggcag gtgtcaagaa
    12241 aaaaacttga cagactataa atttcttaaa gcatttagaa atttgttaga ataggaaata
    12301 aatgtttgaa agatgctatc cgtgaatact attttagaaa aattttataa agaacaccaa
    12361 gtcaaaccct tcatatcgcc tgaacgagat ttggatactt ggcttctaag tcccaaaccc
    12421 gttcccaagc gaaatatgga cttattagca gatgattcac tagcaggaga tatcatttta
    12481 ctatggagaa tccagtttgg tacttttacc actgaaacat gattttaaaa actcccattc
    12541 gaatatgatt caaaattcgc ttagaatcaa tgttttccca ctttttcaaa aaataaattt
    12601 tcatctaatt taaataactt tcaattaagt gtgaattttg cttaaaatca taaaaaaaca
    12661 ccccatggtg tgaaccatga agtgttgtaa atgctgtatt gtagctagtt cttaacgttt
    12721 agagaactgg ctagctttac gagctttctt aagatctggt tccctaaata ctttgagtac
    12781 acttatggca ttgatgcccc taaacatcta aaaactctgg tagaaaaaga gtatgctctt
    12841 gtcgaaactt cttttgactc acttgaccat ctaaatacta ccatgaaaaa gaatatcctg
    12901 aagaagaagg gagttactgg actttctaaa atgaaatctt gcgacctgga tcaagctctt
    12961 catgagcatt tttcagaaga agaattagct ggtcactttc atgtccttct atggactttt
    13021 ttacaatggc attgctatca cacccaatac ctatctaagc gcctggttcg taaactttat
    13081 tgcagctctt cctctaaatt tcctaattgt tgaaccaatt gcccgtttta tactaagttc
    13141 ttttcagaaa ccatttactg gggaagaagt tgaagaagtt gaagattttc aagatgatga
    13201 tgaaatccca actattatct aagccagttc tgtaaactac taatatttga aatccacttc
    13261 cttttagggt acaatggtat aaatgaattt ttgagaggaa cagaatgaaa aaactagcaa
    13321 cccttctttt actgtctact gtagccctag ctgggtgtag cagcgtccaa cgcagtctgc
    13381 gtggtgatga ttatgttgat tccagtcttg ctgctgaaga aagttccaaa gtagctgccc
    13441 aatctgccaa ggagttaaac gatgctttaa caaacgaaaa cgccaatttc ccacaactat
    13501 ctaaggaagt tgctgaagat gaagccgaag tgattctcca cacaagccaa ggtgatattc
    13561 gcattaaact cttccctaaa ctcgctcctc tagcggttga aaatttcctc actcacgcca
    13621 aagaaggcta ctataacggt attaccttcc accgtgtcat cgatggcttt atggtccaaa
    13681 ctggagatcc aaaaggggac ggtacaggtg gtcagtccat ctggcatgac aaggataaga
    13741 ctaaagacaa aggaactggt ttcaagaacg agattactcc ttatttgtat aacatccgtg
    13801 gtgctcttgc tatggctaat actggtcaac caaacaccaa tggcagccag ttcttcatca
    13861 accaaaactc tacagatacc tcttctaaac tccctacaag caagtatcca cagaaaatta
    13921 tcgaagccta caaagaaggt ggaaacccta gtctagatgg caaacaccca gtctttggtc
    13981 aagtgattga cggtatggat gttgtggata agattgctaa agccgaaaaa gatgaaaaag
    14041 acaagccaac tactgctatc acagtcgaca gcatcgaagt ggtgaaagac tacgatttta
    14101 aatcttaaaa accaaaaaaa tacagtatcc acattcggta ctgtatttct tttactctca
    14161 ttcttaagtt aaattattaa aatcccatat ttggtctatc cagccttcat aaaagtctgg
    14221 ctcgtggcag accataagga tagatcccct atattctttg agagcgcatt tgagctcatc
    14281 ctttgcatcc acatccaaat ggttggtcgg ctcgtccagc actaaaacgt tgttttcacg
    14341 attcatcaag agacagaaac gaaccttggc ttgctctccc cctgataata cttgaatctg
    14401 gctttcaata tgtttggttg tcaaaccaca acgggcaagg gctgcacgga cttctgcttg
    14461 attaagggca ggaaaggcat tccagacagc ttcaagagga gtttggcgat taccaccttc
    14521 tacttcctgt tcaaaataac caagttctaa ataatctcca cgctccactt ccccagcgat
    14581 tggcgagata atgcccaaga gactcttcaa gagagttgtt tttccaatac cattagcacc
    14641 aataatcgca accttttgat tgcgttcgaa ggtaagattt aaaggcttag taagaggacg
    14701 gtcgtaacca atttgcaagt tcttggcttg gaagataaag cgccctggtg tacgagctgg
    14761 tttgaaatca aaggatggtt ttggtttctc actttggagt tcgataatat ccatcttatc
    14821 caatttcttt tgacgagaca tagccatatt acgagttgca acacgggctt tattacgagc
    14881 cacaaagtcc ttgaggtctg caatctcttt ctgatggcgt tcgtaggctg cctctagctg
    14941 agatttcttc atagcataaa cttcttggaa ctggtagtag tcaccagagt aacgcgtcag
    15001 ctgttgattt tccacatgat agacaatatt gataacgtca ttgaggaatg gaatatcgtg
    15061 cgaaatgaga acaaaggcat tctcatagtt ttggagatag cgcttgagcc aatcaatatg
    15121 ctcagcatcc aagtagttgg tcggctcgtc caacagcaaa atatcaggct tttcaaggag
    15181 aagttttgcc aaaagcacct tggttctttg cccacctgac aaagaagtta catccgtatc
    15241 catgccaaag tccataacac caagagcacg cgctacttcg tcaatcttag catccaaggt
    15301 atagaaatca cgactctcca gacggtcttg aagttctcct acttcttcca tgagagcatc
    15361 aacatccgcg ccgtcttcag ccattttcat atagaggtca ttgatacgag cttcagcttt
    15421 gaaaagctca tcaaaagccg tacggagaac atcacgcacc gactgtcttt cagcaaggac
    15481 agagtgctga tccaagtaac cagccgtcac atatttggac cactcaacct ttccttcatc
    15541 tggcagcatt ttaccagtca cgatactcat aaaggttgat tttccttcac cattggcacc
    15601 gaccaggccg atatgttctc ccttgaggag acggaaggac acatcttcaa aaattgcacg
    15661 gtcaccaaaa ccgtgactca gatttttaac ttctaaaata ctcattttaa ttccttatct
    15721 tgtttttatg taatcgttta taaaggagcc aagccagata gccacccaaa gtgttggtcc
    15781 acaaatcatc aatctcaaag acacgattga aatcaaagaa aaagtccaag attaattgcg
    15841 tacactcgat tccaagactc acaagaaaac taaaaagaag gacctttttt gttttccgca
    15901 aatttggaaa tagataaagg agttggaaaa tcagaggaaa aaacaagaag acattgagga
    15961 tattttgtaa aaaaatccaa cataattgtc caatgtcact cacttcgccc agtttccaga
    16021 gagaattgaa aggagtcaaa agaaaaacca ggcgtccaag atgctgaata tctggagttc
    16081 ccactcccac ggtagattgt tcttgaggag taaagcaaaa acagacaatg caaatgctat
    16141 agaaaatgac tccccagacc aaaatatgat tataagtctt cttcatcatt aaggatttac
    16201 cgctgcgact gccttctggc ggtcacgttt cattgtgtta gagcgcaatt gtccacaagc
    16261 tgcgtcaata tctgtaccat gctcttgacg aaccacacag ttgacccctt ttttcttaag
    16321 cgtatcatag aaagccaaca cgcgctcttt gggactacgg ctatattggt catgctcact
    16381 aactgggtta taaggaatca agtttacata agacaatttc ttgatgttct tgagcaattc
    16441 agccaattcc aaggcttgtt ctacaccgtc gttgacttca ttaagcatga tatattcaaa
    16501 ggttacacga cggtttgttg tctcaatgta gtattcaata gcagcaaaga gtttttcaat
    16561 cggaaaggca cggttaattt tcatgatact tgaacgaagt tcattgttgg gtgcgtgaag
    16621 agacacggca agattgacct gaaccccttc atcagcaaag tcacgaattt tatgagccaa
    16681 acctgaggtt gaaaccatga tgtgacgagc accgatagcc attcctttat catcattgat
    16741 agtacgaaag aaattcaaaa cattgttgta attatcaaag ggctcaccaa ttcccatgac
    16801 aacgatatgg ctgacgcgtt catcctgacc acgctcatca aagtatttct gaaccagcat
    16861 gatttgcgct acgatttcac cgttattgag gtcacgctgc ttcttaatca aaccagaggc
    16921 acagaaggta caaccgatat tacagccgac ctgagtggtc acacagacag ataaaccata
    16981 gtgttgacgc atgagtacag tctcaattaa cataccgtcg ggcaattcaa agagatattt
    17041 gactgtacca tcagcagact cttgcacaat acgttgtttc aagggattga ccacaaactg
    17101 gtcattgagc ttagcaatca aatccttgga aaggttggtc atttcttcaa atgactgcac
    17161 acgtttacgg tagagccatt cccagatttg atctgcacgg aatttctttt ctccctgctc
    17221 caatacccat tcctgcatgg tttgatgtgc caaactatga attgagggtt tcatttcttc
    17281 tccttattct ctactcactt ctgacgaatg acaaaatgac gttgtccctt gtcctctttc
    17341 tgagaatgct ggtctttctg acgacgtcta tttttcttat ctgcattcga ctttcgttta
    17401 gtttgagtcg gtttctttcc ttttctagaa ggtgtttctt cttccgtctt acgcattttc
    17461 ttgtcaaatg atgctcgctt aggggcttca ttttctaaga caaaataggc acaaccataa
    17521 ctacaatact ctaaaaggta gtcttgtaaa cgactgattt tttcaagttt ttcttctgtt
    17581 cggtcatcct tgtaaaaacc tcgtaggcga agctgttcgt tgctccagtc ccccacgata
    17641 taatcaaact tggttaagac ttctgaaaaa cgctgattaa aagtcgtcac atcaaaggca
    17701 tccttgatat tttcaaccaa ggaaaaagct atcccttccg tttcgacctt gtccccgtgt
    17761 aaatggaact ccggaccagg aaacttgtta tagttgtata attcaggtgc aatttctttt
    17821 cgcatagata tcctttttcc acgattactt aatactttat tctaccataa tttctagcag
    17881 ttagcacgtt tctcataaaa atgaaaaaag tctgacgatt ttatcagacc agaatcttat
    17941 aacctaaaaa gagaagaaca attcttccct ccaactatca ttatttagca gctgcgtaca
    18001 attcatctac tttattccag ttgattactg aaaagaaagc tttgatgtag tcaggacgca
    18061 cgttgcggta tttcacgtag taagcatgtt cccaaacgtc caagcccaag attggttttt
    18121 taccttctga gattggtgtg tcttggtttg ctgttgaagt cacttcaagt ttcccttctt
    18181 tgttgacaac caaccatgcc caacctgaac caaaacgagt tgttgctgct gcagtgaagg
    18241 ctgcttggaa ttcttcaaat gaaccaaatg ttgcatcgat tgctgctgcc agttctgctg
    18301 aaggagctgt tttctcggga gtcatcaatt cccagaaaag agcgtggttc aagtgtccgc
    18361 caccattgtt gataagtgct tgacggatat cagctgggat agattctaca tcagcaagca
    18421 aggcttcaag gtcttcaccg atttcagggt gtttttctaa agctgcattg gcattgttga
    18481 cataagtttg atggtgtttg tcatggtgca aatgcattgt ttccgcatcg atgtatggtt
    18541 ccaaagcgtc gtatgcatat ggaagttctg gtaagataat agccatctgt aatacctctt
    18601 tttctttcta tatgaaaatg ataacgcaaa cattcacttt tttcaagttt tttgcttata
    18661 gataaggaaa tcactgacat actttctaat aaaataagca aatcagcaag aaacccacga
    18721 caagataatc ctgacgcggg ttgtagtttc aacaaatgtc aattgacctg actagcaatc
    18781 tgtaagagtg ccttttcaaa aaggaaacct ttttcataaa gacctgtctt aatctgatag
    18841 tctgtctcaa tcaaatagga aatagcttgc ttcagaaagc tcaaagaaag tcctctcgaa
    18901 tctcttaatg caaacttgat ttgataagga tttgggttac gtcccagata actacctaaa
    18961 ctacttgcaa tctgcgattc tgtttggcca gactccgcca aaatcttcac ctgagtaaaa
    19021 gtccgaaatt gtcccagcat gactgcaatc agtttgattt catcttcccc ttgcaaggtc
    19081 aagtctctca ccaaatcgcg cgcctgatcc atctttttag tcagaataaa ctgagttaaa
    19141 tcaaaaatat tgtcctgcaa ggtcttggga attgcgttaa caatatcctc ttcctcgata
    19201 acagaatccg ccttatagga ctgtaaaaag agaagatttt tctggatttc gctaaattga
    19261 aaccccgact tgatgaggag attttcaaaa gaatgattgg taaactgcag accttgtttc
    19321 tgactccact tttggaagta ctggcgcaat tcttgttctt ttacttctac tgcatcgaag
    19381 gccttggcat cacgcttaag taatttgact aaccgtcttt tgctatccag ctttccttct
    19441 gcaaagatta tcaacttggt tgttggagaa ggattgtcaa ggtattcctc aaatgactta
    19501 agctcatcat ctgtcaaaaa gcgtttctta gcagtcgtga tatccataaa ataatctaat
    19561 atcacgattt tctcatccgc aaagaaagga aggctgacca actccagttc cacatccttg
    19621 taaactactt ctttcatatc aaagtaggca aagttgaggt cagcagaatc atacccaatc
    19681 tgtttcaaca cttgactctt catcacttca aactgaccct gatctgtccc tgtaaatagg
    19741 ctcaggctcg gtaaatttga taaagtcaac ttctgacttt cttcaatggc tagcatcgtc
    19801 tctcctttct tcagattttt cgatttaatt tagtcaatat agcgcaattt cccacggaaa
    19861 tcttctaagc tctcgtagcc tttttccacc atgattgctt tcagttcatt ggtaatgcgg
    19921 tcaaaagcac tgacgccttc tttgtgaagg gtcgttccca cctgcaccat acttgctcca
    19981 cagaggatgt gttcaaaggc atctcgacca gtcagaacgc cacctgttcc gataatttgg
    20041 atttgaggat ttaaacgttg ataaaaggcg tgaacattgg ctagagcagt cggtttgatg
    20101 tattctccac caattccacc aaaaccattc ttaggccgaa taacgacaga ttcgtcttct
    20161 atatagaggc cgtttccgat agagttaacg cagttgacaa acttgagcgg atatttgttg
    20221 aaaatagctg ccgcttgatc aaagtgaaca atatcaaaat aaggtggcaa tttaattcca
    20281 agaggtttgg tgaagtaagc aaacacttct gccaaaatcc ggtctgttgt ctcaaaatca
    20341 taggcaatct gaggtttacc tggaacattt ggacaggaaa gatttagctc agtcagacca
    20401 cgaaaatcac tctcttggac ttttttcaaa atagtatggg tttcctctgg agacatgccg
    20461 accagagata agaagaaagt tcggttcgac tctttttcct gcaaatctaa aagataatcc
    20521 aaataatagt ctaagccatt atttggcaag cccatagagt tgatggaacc aagtggaaca
    20581 tcttggtagc gtggctcagg attcccctga cggaagtcca aggtcgctgt cttagtaaca
    20641 aaggttcctg ccgctgagtt tttgacctct tctaactcct ctatcgtcat acaagccaca
    20701 cctgctgcat tcatcaagca attgtcaaac tcaaaaccag caatttgtgt tttcgttgat
    20761 accatgattc taatcctcca gatttctttt attgctaata ttataccata attttaattc
    20821 taggtttact agattctgtg gttctatcta tttattcgga aaagaaagtc tagtacagaa
    20881 gtcatgctat ggaaacagct agtgtattag aagtttgaac aaggcttggg taacagactt
    20941 ttgaatgaag tccaagcaac aaggagaaat ctccaccatg agtccattcc atgactctgt
    21001 tgctctagaa aaccttgcaa tagtcaagtg ataacgaata aaactttgga ttgaaatatc
    21061 cccaagatta tctattacga ggagaaatct taacctttat catttttaaa gaaatatagt
    21121 aaaatgaaac aagaacagga gaaatcgatc aggacagtca aattgattgc taacaatgtt
    21181 ttagaagttg aggtgtacta ttctagtttc aatctactat acatgtaaat ctctactttc
    21241 gcaaaatgga ttttcagaac agtatcccag tatagttaaa aactataaaa aagagaggac
    21301 gttcccctct taaaatctta ttttactgct tctttcaaag catctacctt atccaaacgt
    21361 tcccatggaa gatcaatatc tgtacgtccc atgtgaccgt aagccgatgt ttgacggtaa
    21421 attggacgct tgaggtccag catttggata atccctgcag ggcgaaggtc aaagatttga
    21481 cgagccgctt tttcaagttg actttcagct actgttcctg taccgaaagt atcgatacga
    21541 acagaaacag gttgcgcaac accgatagca taggccaact gcacttctgc cttcttagca
    21601 aggcctgctg caacgatatt cttggcaata tagcgagccg cataagaggc tgaacgatcc
    21661 accttagtcg catctttacc agagaaggca ccaccaccat gacgagagta gccaccataa
    21721 gtatctacaa taatcttacg accagtcaaa cctgagtccc cttgaggacc accgattaca
    21781 aaacgacctg tcggattgat aaagaatttt gtcttatcat caagataaga agatggaata
    21841 acttctttga tgaccttgtc aatcacatct tgatggattt gttcattagt ggcctctgga
    21901 tcatgctgag tagaaataac gactgtatct acacgtaccg gacggtcatt ttcatcgtac
    21961 tcaactgtaa cttgtgattt tgcatctgga cggagatagc taatttctcc agacttacga
    22021 agttctgcca gacgacgaac caatttatga ctgagtgcaa ttggcaatgg cataagctct
    22081 tctgtttcat ctactgcaaa tccaaacatg agcccttggt cacctgctcc aatcaagtcc
    22141 agtggatctt gatcagcatt tccacgaacc tccaaggctt cgttaacacc ttgagcgatg
    22201 tcaggagatt gttccaccaa agatgggtgt actcccaccg tctcagcaga aaatccatat
    22261 tctgtattgg tataaccaat ctctgcaatg gtatcacgaa ccacacggtt aatatccaca
    22321 taggcatttg tagaaatttc accaaaaacg tggacagaac cagtatatac agctgtttca
    22381 gcagcaacgt gcgcctctgg atcctttgct aaaatagcat ccaaaatcgc atctgaaatt
    22441 tggtctgcaa tcttatccgg atgcccctca gatacagatt cagacgtgaa taatttacgt
    22501 tctgacataa aaatgtcccc ccttaaaaaa tattgttata gagttacaaa gtactgatag
    22561 gaaaactctt cgtaataaat acctaccatc ttatcgggac tatataactt tatcattata
    22621 gcatttttaa tcgcaatttg cagtctttaa tgtagtgttt cggtttagat agttcgttct
    22681 cataaagcaa aaagttggag ctcagtactc caacaatttc tattaaaatg tttgacgttt
    22741 agctttacgc tctgcacgac cgcgagcgcg attttcagca cgcttggttt tacggcgctt
    22801 ttcatcaacc gcccattgaa ttttcttctt ataacccggt ttgacttttt tctttttctt
    22861 tttaaccaaa ccaatcattt cgatatcaag tttatcttgt tttttctcac ggttggcacg
    22921 acgatcacgg tcataggtat cttgaaattc cccgtctttg accatcttag gactaaactt
    22981 gattcccaat ttctccaact cacggatatc cgagtcatca cttggctgat aaagggtaat
    23041 agctgtacct ggtaggccat ttcgtccagt acgaccaaca cggtgaacaa aaaaagataa
    23101 gtcttgcgga atggcatcat tgatgacatg gctgacacct tcaatgtcaa tcccacgtgc
    23161 tgccaaatct gttgcgacaa tatactcaaa atccagattt tgcacctgat tcatgattcg
    23221 cttgcgttca cgaggggcaa tatcgccatg gatttttgca accttcaagc cttgagcagt
    23281 cagatatgaa tgcaattcat cagcacgcgt tttagtgtta acaaaaatca ttgccaaata
    23341 cggctgcatc aactgagtca actggtaaat ttgagcattc ttatcatgtc ccttggtcga
    23401 aatcaaccaa ttatcaatgg tgtcagaaat aaccgttttg gtcttaattt tctccataac
    23461 aggattggat aagtattttt tcaagaatgg ttgcagtttt tgtgggatag tcgctgagaa
    23521 gaccatgaat tgcaagtctt ttggaagact gccagcaatc ttatcaacag tttccaagaa
    23581 tcccatatcc aaggtcatat ccgcttcatc aacaacaaat gtcttggctt tatgaatagc
    23641 taaatcacca gatttaacca agtcgtagat acggcctggt gttccaataa caatatgagg
    23701 ctgattgctt gccaatttct caatctggcg agccttatcc gtaccaccca cataattaac
    23761 cacacgaact tcgacatctg agtgagctga aatctgacgc gctacttggt aaatttgagt
    23821 agccaactca cgactcggtg cagtaatcac tgcttgtaca ctatcgctag cttcatctaa
    23881 ttgctggaaa atcggtaaca agaaagtatg agtcttacct gaacctgttt ttgattctcc
    23941 tactaggtca cgacctgcca aaacaatagg aatcaacttg tcttgcacct ctgttggagt
    24001 tgtaaatttt aactcctcca aggcttctct aatatagttt ttaaattgaa atttcgtaaa
    24061 tgacataaca tcctcgattc tatctatctt atcaattata ccatatttta ttccattaca
    24121 gtagtctcac ttatttaggc tatttccagt agcttctcta gtaagaaaag gctggaattt
    24181 tatagttcca acctcttttc agttattatt tccagtttaa catagcattc aagccatagt
    24241 gatcactcac ttgtggactc ttgttaccat caaatacgac atgtaaattt tccaccgcta
    24301 actctttggt agtaaagaca taatcgattc gaaggggttc agtgttccct ttccagccat
    24361 caatttcaag cggaacagta tagctaccac ttttctcttg agcaacttca aatgcgtctt
    24421 gtaagcctaa tggactagct aaaatagctt ggtaaccttc ctgacctgct gggttgttaa
    24481 aatctccagc tagtaaaagt ggcttgttca attttttcaa gacagcctca aatcgtgccc
    24541 attcttcttg gaaaccttta tcccaccaag agagatgaac actggcaact gctagctcct
    24601 tgccatcgac tacagtttca gctagggcaa cacggcgagt atgatagtct gttggatcat
    24661 ccacatctga aaccaaaatt tctctggctt caataggtgt tttagacaag atagccacac
    24721 cttcgtggta gcggtcatag ccgatatggt tataagccca ggtccagtag taatttttcc
    24781 cttgctctaa caacttttca accaagagtc taacataatg gtcttggtga ataggctcag
    24841 ctgctggcaa agcttgataa aggtcattaa cctccacctc tgacgaggtc atctcctgat
    24901 tgatttcttg gaaacaaatc aaatcatagt ccttttcaag aatatcttca agcaaaatct
    24961 ggaatttttc ctctgcttct ttctccatcc aactgtgagt attgagtgtt aaaaatttca
    25021 ttcttttctc ccaaaataag aggttggaat acagcttcca acctcaagta tattacaatt
    25081 ctactttagc aactgctgtt ttagctgcaa gagaacctgt tttttctaat ttaactgatt
    25141 taattgcatc accatttgtg aagacaacta ctgttgaagt ttcacgtcct gctgcacgga
    25201 tagcatccaa gtcagctgtg acaaggagat ctcctgctgc aactttttgt ccttcagcaa
    25261 catgaactgt aaatggttta ccttcaagac ttactgtgtc caaaccaatg tgaaccaata
    25321 cttcaagacc tgcttccgtc acaataccaa aagcatgttt tgttgggaag atgcttgaca
    25381 cagtacctga aactggagat acaatgtttc catttgcagg ttctactgca aatccatcac
    25441 ccatcatttt ttgagcaaat actggatcct ttacttgttc caaaccaaca acttgaccgt
    25501 ctgctactga ataaacttcc tcagtaagat ctttgaagtg aacagtgttt tgttgtgctt
    25561 cagtcatttg gcttggaaga gtttcaggaa tgatttcacc tgaatcaagg atatcttgga
    25621 tatcagattt caaaatgtca gcttttggac cgtagatagc ttgaacccct tgtcctttca
    25681 tcacaagacc catagctcct tctgctttcc attgctctgc atttcctact ttatctgcat
    25741 ctttaacagt tacacgaaga cgagtcatac atgcatcaac atcaacgatg tttacacgtc
    25801 caccaagaag gttgataatg tttacagctt gagagcctgc tgcaactttc acttcgctgc
    25861 tggtttcttc tgaaccttca gcagtttcgt agtttccgtt gcgccctgga gttgcgtaat
    25921 tgaatttttg aatcatgaag tttgcgataa agtacatgat tacagcaaag agaacagtta
    25981 cccaaacgaa gttaacgata tccataccaa taccagcact gattgcaata ggtgtacgag
    26041 tcaagaactc gattgaaccg aatgagtgca tacgtaggtt tacgacgtca gccatagcga
    26101 aggcagcacc ttgaacaagt gagtaaacaa gatacatagg tgttgcgatg aacatgaaca
    26161 tgtattcgat tggttcagta acccctgtca agaatgttgc aagagctgtt gcaatcatca
    26221 tacctttgta tttatgtttc ttgtcagcat caacattacg gtagatagca acaatcacac
    26281 ccatcaagat accgaatgaa ccgatcattt gtccaacttt gaaacgagct ggatgtactg
    26341 tatctaacaa gtgttgatat tgactagcat cagtaccttt aaggtttaca aggtctgtta
    26401 cccatgcaag ccatagtggg tcttgaccga atacttgagt acctttagct gcaccagtta
    26461 aaatgtcata agtaccacca agagctgtgt agttcattgg gatagtcaac atgtggtgaa
    26521 gaccaaatgg caagagcaaa cgttccaaag taccatacaa gaatggtgca agaattggag
    26581 cagtttcttg tgagttggca atccagatac cgaagttatt gatacctgtt tgaactactg
    26641 gccagaaagc agcaagtaga attgcagcga ttgctgaacg aagaataact acaaatggta
    26701 cgaaacgttt cccgttgaag aatgaaagtg catcaggaag tttacggaag ttgtagtatt
    26761 tgttgtaagc agttgcccct acaaaacctg agataatccc tacgaatacc cccatgttca
    26821 aggctggagc ttcaagaaca ctgataaagt aatcagcaac tttgattgaa ccaccaaaga
    26881 aagtagttac catagcatct ggatttttca acatatcgcc tgatacacca aaaattgtac
    26941 cagtgatacg gttaatcaag atgaaggcaa gaccagcggc gaaagcacca ccagcacgtt
    27001 ctttagccca gcttcctcca atggctaggg caaacaaaat gtgaaggtta ccgataaccc
    27061 cccaaccgat ttgctcaaga attccacctg tgatgacaag tggtgtaaag gttgggttaa
    27121 tcatcacgat agacttaccg attgaaatca tcaaaccagc agccggcata accgcgataa
    27181 ctaccatcaa agccttaccg aatttttgcc aaaattcgaa agacaagaca tttttgaatg
    27241 tatctttcat cattcaaatc tcctttattt ttatttaggc aaacgtttta cgaaaacgtt
    27301 tgcaccttct atgatttaat tataccactt taattttttt tgtaaaggct tttataaaaa
    27361 aattacactt ttttctaaaa aatttctagt gcgccaaatt tcaagttcaa attagccatc
    27421 aagaagtctt ctctggggga cttctttgga agctcttttc ttctgcgcat ctcttttcaa
    27481 aaactcttgt agcaaaaaag gagattttac aatctcctca taaaagcagc tattttacct
    27541 aaatcttcaa gaatcggcgc atggatattc ctgatcccaa tgaaccaatg aaaaccccaa
    27601 tcacaaatag tagggcaatc atcaacggac taaataaatc tggactaatc atggatagat
    27661 tttgccctac caacgatttg ttgacagatt ggtaaacaat ttgataaaca ataaagacca
    27721 aaacagatgg tgcgatagct cccaataaac cgataaaggc tccttctaac aagaacggtc
    27781 cacggatata actgttttta gctccgacca agcgcatgat ttgaatttcg cgactgcggg
    27841 aaataatggt aatacgaatg gtatttgaaa tcaagaaaac tgcgataaaa attaacaaag
    27901 cggcaatccc tagtccccaa acacggataa atgaagctaa cttgaagagt ctttctgtat
    27961 tggcaccgcc atcttgaacc tcagagacac cttcaatttt tttagcatct tcggctatag
    28021 tttttacatc atttggagtg tttgcctcta caatataggc atcatagaga ggattggcat
    28081 ctccttcaaa gattttccag ttatctccca ttatctcggt taatttttca tattgttctt
    28141 ctttacttga aaaggtaaca cttttaaccg tagacatgtt cttcaaagaa tcatatacct
    28201 tgtggtagtc attatttgta acagtttgac cttctttttc aattgtctga ctattatctt
    28261 ccacatcctt tcggatataa actactacac ggacattatt ttcaatatct gtagctagtt
    28321 tcgctgtatt gaaaataaca gatgcaaata ttgccaccaa ggtcaaagta atcatgactg
    28381 aactgacagc agctactgtc atccaaccat ttcgtttcaa actttttaag gcttcaaata
    28441 aatggcgaaa aaatctacta atcatcgtat ccatactctc cttttgattc gtcacgaacg
    28501 acacggccat tttcaatggc aatgacacgg tggcgcaagg tatttacaat ctggctatta
    28561 tgagtcgcca tcaaaatagt tgttccttgt aggttaatcc gttccaagag attcataatt
    28621 tcccatgaat tatctggatc cagatttcct gttggctcat cagctatcaa tactttggga
    28681 ttatttacaa ttgcacgcgc aatcgcaatc cgctgttgct ccccacctga gagttcattt
    28741 gggaaagaac gaaccttatg cttcaatcca accaagtcca aaacttccat cactcgtctt
    28801 ttgatattac ggcgattttc cccgattact tccatagcgt aagcaatatt ttcatagaca
    28861 gttttctttg gtaacaattt ataatcttgg aagacaaccc caacactacg acgtagaagc
    28921 gggacatctt tctttttgat cttaaccaga ttaaaaccag caactgatag gcttccttta
    28981 tcgattttta cttcacgata cagagaacga ataaaagttg acttccctgc tcctgaaggt
    29041 cctacgatgt aagcaaattc ccccggttga acgctgaccg aaacaccgcg tagagcagtc
    29101 gttccgttgt cgtatttttt aacgacatct ctcatttcaa taattgacat gtgagttcct
    29161 ttctatctta gctaattcgc cacttgagat aagcatcgat aaaaccatct aggtccccat
    29221 ccataacctt atctacctga gcaacctcaa agctagttcg gtgatctttt accatagtat
    29281 aaggcgtgaa gacataagaa cggatttggc ttccccaagt gatctccttt ttctcacctt
    29341 tgagagaatc tacctctgca gccttcttct cttgctccat ttgatagagc ttagcctgca
    29401 acatcttcat ggcacgatct ctatttccat actgggtacg atccactgtt gattggacaa
    29461 caattccagt tggaatgtgg gttaaacgta cacctgttga aaccttattg acgttttgtc
    29521 caccggcacc acctgaacgg aaggtatcca tcttgatatc atcttcacgg atttccactt
    29581 caatagtatc atccaattct ggcatcactt ctacagatgt gaaagaggta tggcgacgtt
    29641 tggcagagtc aaatggtgag attcgcacta agcggtgaac acccatttct gacttgagga
    29701 gaccataggc attaggccct tcaaatgata aagttaccga cttaatacca gcctcatcac
    29761 ctgcttggta atccaacact tccactttaa agcctttagc attaccataa cgagtataca
    29821 tacgaagcaa catatcaccc cagtcctgcg cctcagtacc accagaacct ggatggattt
    29881 ccaagatggc attgttgtgg tcataaggtt ctgacaagag tagagtcatc tcgtagctgg
    29941 tcattatctt atcaagttcg gctaactgcg ctaccagttc atcatgcact gactcgtctt
    30001 cagccaaaaa atccaataaa atttcgactt catcctgcaa ctcttccatc ttatggaagg
    30061 tattgtaagt gttttttaat tcatttaatt cttgcgacgt tttttgggcc gcaatattat
    30121 cgttccaaaa atcaggttct gtcatcttgt tttccaagat ggcaatctct tcctctagcc
    30181 cttcgaggtc aaagagaccc cctgaaagaa gctaattttt cacgatttgc gtcaatttgc
    30241 tgacgaatta ctgaaatgtc cataaatact ccttttttac attatttcat tatagcatat
    30301 tttatcattt ctttccatct ttttctctaa tccccttttc atgaaaaaag aagcctttgg
    30361 gcttcccttc ttacaagact tttgctgaag tgcgagcgat ttcttccact tgaataccat
    30421 ttgcttcaaa tttttctttc aaggctggta aatcaattga tccatcgatt tgcacttcga
    30481 taatgacctt accatcctta cgcggaatat tgactgtatg ggagatattc aaattttctt
    30541 ctacaatcaa agaaacaatt tttccaagaa caccaacttc atcttctgta acaaagcgta
    30601 cacgaatccc ttcttcgcca taacctgcaa tttcaagaaa agcttggaaa acgtcacggt
    30661 cagtaataac tccgtatact tgatggttat ctacgacagg gagaatacta atcttatttt
    30721 tcaacatcag ataagttgca tcttctagac tagcatagcc tgagacagtg acaacatcgc
    30781 gaatcatgac atcttttact tttgtcttat tcagaagata attcatctca tagatagaaa
    30841 gacttgttgc tttagatgga cttgcttgtg caatggttcc ctcagtcacc aaaccaacta
    30901 attgatcatt ttcgataaca ggcagacggt gcaaaccttg ctctctcatc aaatctgctg
    30961 catgagatac tgttgtatct ggactaatat aaactacctt gcgggtcata aaatctttaa
    31021 ctgccatgag acttctcctt ttctattctt atccctatta tacaatcttt ttgtaaatct
    31081 atcaaacgct tacatttctt tttcgaaatt cagaaaagta tgaataagct agcaaaaaga
    31141 gctctgaaat cgagctctgt gaatgaaggt aagaaatttt tcattcgatt ttttcaatta
    31201 ttagaaatta agctttcaat gtagatgcag atttgtttgc aatctcaatc taccgactaa
    31261 aaaggtcccc cggactatat tgatgattac ttcgtaatct ccatctgccg actaaaacaa
    31321 tccactggat tgttttagcc acctagatat gcttttctga cttcttctga tgaagcgagt
    31381 tcttttcctg ttcctgatag gacgattttc cctgtttcca gtacatatcc tcggtcagag
    31441 attgcaagtg ctttattggc attttgttca atcaagagga ccgttgttcc ttgcttctga
    31501 atatcttgaa tgatatcaaa aatttcttgg ataaagattg gggcaagtcc cattgatggt
    31561 tcatctaaaa gaagaagttt tggtgttgac atgagggcgc gtcccatggc aagcatttgt
    31621 tgttcccccc ctgaaagagt ggctgcatct tggttcttcc gttcttcaag acgaggaaag
    31681 cgtgagaaaa ccttcttcaa gttagcttga ttttcttcac gatttttctt taagaaagct
    31741 cccatttcaa gattttccat aacagtcaag ccaggaaaga cgtggcgtcc ttctggaact
    31801 tgtgaaagac cacttgccac gattttctga gctggcattt tttggatttc ttgacctaaa
    31861 aattcaatct ttcctgaact tggtcgaacc aaacctgaca aggtgcgaag aatagttgtc
    31921 ttacctgcac cgttggcacc gataagggaa acaacttctc cttcattaac ttcaaagctt
    31981 acatcacgaa ctgcttggat cataccgtaa tgcacagaaa gattttcaac ttttaacata
    32041 gacattaggc ttcacctcct agataagctt cgataacgcg tttattggtc ttaatttcgt
    32101 ctggagttcc ttgagcgatt aaacggccat agtcaagtac gtagatacgt tctgttactt
    32161 ccatgaccag attcatatcg tgttcaatca acatgattgt aatcttaaac tcatctttga
    32221 tacgacgaat taactcagtc aattcggctg tttcctgtgg gttcatacct gctgctggtt
    32281 catctaagaa gagaatttta ggttccgtag caagggcacg aacaatttcc aaacgacgtt
    32341 gttgtccgta ggaaagattt ttagcaagag tctctgcatc accatctaaa tcaaagattt
    32401 tcaacaattc caaagcttta gcctttaatt ctttttcact cttgtaaaaa gctggtaagc
    32461 gtaagaaact agtaaaaaca tgctgtttgt gatggtttcc aaaagcaatc aaaacattgt
    32521 ctaaaactgt taaatcttta aaaagacgga tattttggaa agtacgtcca agtcccaaag
    32581 aggcaatctt ataaggtgat ttcccattca aaaggtgacc atctagggtt actgttccct
    32641 cgcttggttc ataaacaccg gtcaaaaggt tgaaaagggt ggttttccca gctccgtttg
    32701 gaccgattaa tccaaccagt tccccttcgt tcaattcaag agtcacatct ccaacagctg
    32761 ttagaccacc aaaatgtttg gttaactgtt ttacttcaag taatgccatt agttttgttc
    32821 ctccttctta gattttttaa agaaacgtga taggctcagt tcccacgttc caaggagtcc
    32881 acctggtctg aaaatcatta ccaataccaa ggccaaagcg taaataatca tacgcacact
    32941 agcaacatct tggagaagca tattcaaaat tcccagaaca atagccgaaa caatcgcacc
    33001 tgtaatggaa ccgagtccac caaatacaac aataatcaaa acgttgattg agttgatgaa
    33061 ggtgtaatct ttcggtacaa cagacccgat aaatcctgcc tgaagtgacc cagcaatact
    33121 tgcagtaatg gcaccaaaga caaaagcgat gattttaatt ttagtcgtat taaccccaac
    33181 tgactcagca gcgatttcat cttcacgaac agagagggtt gaacggccaa ttggactacg
    33241 caagaagttc aaggttgcaa tggttgtaat cacgacaaag aagtaaacca tttgccaagt
    33301 tgtaaagtta ggaatcccta agatacctgc cgcaccattt gtaaggcttc caccattgat
    33361 gataaagata cggataattt cagaaacacc tagagttgct accgcaagat agtccccctt
    33421 caagcgcaag gttggaatgc cgacaagtaa ggcaactgct cctgaaagca aagcccctac
    33481 aagcatagct ccaaagaagg caccgtaggt tggtgattta gaaccaataa tagctgctgc
    33541 ataggcacca atcgccatga aaccagcatg accaagtgaa aattgtcctg aaaaaccaac
    33601 gattaagttg agaccaacag ccaaaataat attaattcca atttgttgta aaatctgtac
    33661 atagaataga ttaagtactc cgactgaaac cagtacacta atcaagctat agccagctaa
    33721 caaaaggagt aaccatagaa tattaacttt taaattttcc ttcatcgttt acaccttctc
    33781 tttcacattc ttaccaagga taccagctgg gcggacaatc aagatcaaca acaagattcc
    33841 ataaacaatg gcatcacgga aatctgacat cccaaaggct gtcgcaaagg tttccaatag
    33901 accaatcaca aagccaccaa gagcagcacc aggaataatt ccgataccac caagtactgc
    33961 ggcaacgaaa gatttaagac ctggagtaac ccccatcaaa ggctcaagag agttataata
    34021 aagagcaatc agaacaccag ccgcacccgc aagagcagaa cccaaagcga aggtaaagct
    34081 aatcgtacgg tttacattga tccccatcaa ttgcgccgcg tcgctatcta ctgatactgc
    34141 acgcatggct ttccccatct tagtcttttg gacaatgact tgtaacaaaa tcatcaaaat
    34201 caaggaaatg cccaaaatca ttaactgcac atttgttaag ctaattggtc ccaaatcata
    34261 tcgaactgtt tgaatcgctt gagggaaggc acgggtattg gcaccaacca gatagaccat
    34321 tccatactcc aataggaaag aaaccccaat agccgtaatc aaaacagcaa tacgagtaga
    34381 gtggcgcaaa ggtcggtaag caagaaactc aatcacgaca ccaagaatag ctgtcgctag
    34441 catagctaca ataagcgcta caaagaaatt catttggaaa gaattgatca agaaataacc
    34501 gataaaggct cccatcatat aaatatcacc atgggcgaag ttgatgagct tgataattcc
    34561 gtaaaccatg gtatatccta gggctaacag cgcgtaaaca ctacctagaa tcaaaccatt
    34621 tacgagttgt tggagcataa gattcactct ttctatttat aattccgagg gttttccctc
    34681 actttttgat aggttct
//
LOCUS       DAVDHZ010000022        32610 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000022 DAVDHZ010000000
VERSION     DAVDHZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.022"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VUR46_001221"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VUR46_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET5456650.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLVGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VUR46_001222"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VUR46_001222"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET5456651.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VUR46_001223"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VUR46_001223"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET5456652.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VUR46_001224"
     CDS             complement(3790..5058)
                     /locus_tag="VUR46_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET5456653.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLLQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VUR46_001225"
     CDS             complement(5178..5546)
                     /locus_tag="VUR46_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET5456654.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VUR46_001226"
     CDS             complement(5539..5805)
                     /locus_tag="VUR46_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET5456655.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9378)
                     /gene="mfd"
                     /locus_tag="VUR46_001227"
     CDS             complement(5863..9378)
                     /gene="mfd"
                     /locus_tag="VUR46_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET5456656.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDTVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTNTRTKGNAELILLIDAYLPDTYIS
                     DQRHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQ
                     RVERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDY
                     EILEGLLIFGESLLEIKESKEKNSI"
     gene            complement(9379..9948)
                     /locus_tag="VUR46_001228"
     CDS             complement(9379..9948)
                     /locus_tag="VUR46_001228"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET5456657.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10019..11134)
                     /gene="ychF"
                     /locus_tag="VUR46_001229"
     CDS             complement(10019..11134)
                     /gene="ychF"
                     /locus_tag="VUR46_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET5456658.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11254..12267)
                     /locus_tag="VUR46_001230"
     CDS             complement(11254..12267)
                     /locus_tag="VUR46_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5456659.1"
                     /translation="MDFEKDGSTVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKF
                     KIDKYLLPAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYA
                     VSLQAIPFNPARDIIVPRRKEKKGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLY
                     KTLLATGLRIRECLALEWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKT
                     VLMLRLYKARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFH
                     AFRHTHASILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKL
                     KSS"
     gene            complement(12268..12420)
                     /locus_tag="VUR46_001231"
     CDS             complement(12268..12420)
                     /locus_tag="VUR46_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HET5456660.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQA"
     gene            complement(12516..12968)
                     /locus_tag="VUR46_001232"
     CDS             complement(12516..12968)
                     /locus_tag="VUR46_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET5456661.1"
                     /translation="MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETME
                     NIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK"
     gene            complement(12968..13972)
                     /locus_tag="VUR46_001233"
     CDS             complement(12968..13972)
                     /locus_tag="VUR46_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5456662.1"
                     /translation="MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNS
                     QLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAR
                     EKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            complement(14121..15077)
                     /locus_tag="VUR46_001234"
     CDS             complement(14121..15077)
                     /locus_tag="VUR46_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5456663.1"
                     /translation="MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTI
                     TGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMF
                     FNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISK
                     NNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINS
                     LNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFC
                     VTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD"
     gene            15235..15468
                     /locus_tag="VUR46_001235"
     CDS             15235..15468
                     /locus_tag="VUR46_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5456664.1"
                     /translation="MEQWTLKACRVNAGYTLRQIAKKVNKNFQTVSKYEKDSTYIPFE
                     LLKELSAIYQVKLDNIFLGDSTKKIELNKREVQ"
     gene            15558..16163
                     /locus_tag="VUR46_001236"
                     /pseudo
     CDS             15558..16163
                     /locus_tag="VUR46_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518114.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            16175..16435
                     /locus_tag="VUR46_001237"
     CDS             16175..16435
                     /locus_tag="VUR46_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456665.1"
                     /translation="MENEFKTVTNAKGLEIPKYPKDFKKLVEMDRQLAEYLCMNYENL
                     DNEDLGAFLETVEQGFSWILDLIESKDLLYSPQTGKKARKRQ"
     gene            16664..16834
                     /locus_tag="VUR46_001238"
     CDS             16664..16834
                     /locus_tag="VUR46_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456666.1"
                     /translation="MGKTLGRPKSDNPKNKQLKIKMTEQDFNNLEELAKKKNMTKTDI
                     VMRGIELVKSEP"
     gene            16989..17444
                     /locus_tag="VUR46_001239"
     CDS             16989..17444
                     /locus_tag="VUR46_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456667.1"
                     /translation="MRKKHQVVKFKDIAEKLPELEGKRLEEITKVLGYRNLESCRTNL
                     CKLKQNNRLDFTLEKGVYSKFALLDGTVKEELEDKELSERGRYLKSVDRYKAMLNAFS
                     IAFDSTVKAETRQKAEHDGLKALDRIPDKHYALLYDMMEGEDGSKNPLR"
     gene            17419..17568
                     /locus_tag="VUR46_001240"
     CDS             17419..17568
                     /locus_tag="VUR46_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456668.1"
                     /translation="MEAKTHFARFMRRGMELARQLHSKEIQRDEFDRAWKRLGDQIEN
                     ETKKN"
     gene            18002..18502
                     /locus_tag="VUR46_001241"
     CDS             18002..18502
                     /locus_tag="VUR46_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456669.1"
                     /translation="MISDKLEAISTNLEEIQKSLVGAETVLAKREISRVLNDLDDVYS
                     ELTSTEYHEQQQTIKEQTEKMKQRGIAEVIGELEEREESYYRNFWGDTQFIRLLSNFD
                     GFLFLNTYLAEITKENTYPMEQSQLLNYVWEVIAVDIAKKKRGKKNVLDSWTDSSLYT
                     RGMMID"
     gene            18514..18714
                     /locus_tag="VUR46_001242"
     CDS             18514..18714
                     /locus_tag="VUR46_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456670.1"
                     /translation="MTLDLGKMTQAEFDEVMADIKARNPNLLQLITDFLDRKVTPEEV
                     DDLLNMERAEQVEYIKNYQARA"
     gene            18716..18931
                     /locus_tag="VUR46_001243"
     CDS             18716..18931
                     /locus_tag="VUR46_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456671.1"
                     /translation="MNELDISNTHAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPDYGRYIQLAGVRVSGGME"
     gene            18928..19221
                     /locus_tag="VUR46_001244"
     CDS             18928..19221
                     /locus_tag="VUR46_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456672.1"
                     /translation="MSYTMNLYPDIEKIPDEPYFTKDIFLATCMDNATKLAVTMSLLT
                     EQTLDLETETAILKTLDTIIETQKDILQGVASGQITFVNKSKGEEGLDESIRE"
     gene            19202..19543
                     /locus_tag="VUR46_001245"
     CDS             19202..19543
                     /locus_tag="VUR46_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5456673.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            19536..19811
                     /locus_tag="VUR46_001246"
     CDS             19536..19811
                     /locus_tag="VUR46_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456674.1"
                     /translation="MFSLSRESEHDLTHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG"
     gene            20223..20633
                     /locus_tag="VUR46_001247"
     CDS             20223..20633
                     /locus_tag="VUR46_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET5456675.1"
                     /translation="MEAVSSALFGYSYILYPTIKQGLYLELAALESGIIKKQELSNTR
                     VQTSRVNTTENNLINVLKLKEYTLQRIERLTEERMEISRLIDKLANPLERSVLRLFYL
                     NVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG"
     gene            20790..21182
                     /locus_tag="VUR46_001248"
     CDS             20790..21182
                     /locus_tag="VUR46_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5456676.1"
                     /translation="MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLP
                     DQWNLTSKHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATS
                     STSYHRYKQIAVLNFARIHQNGELEVYK"
     gene            21236..21382
                     /locus_tag="VUR46_001249"
     CDS             21236..21382
                     /locus_tag="VUR46_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456677.1"
                     /translation="MIEDFLIDLDNIQLEDMEIDFNMDIDIDLNIDFDLDGLDLTLLQ
                     ELEA"
     gene            complement(21813..22007)
                     /locus_tag="VUR46_001250"
     CDS             complement(21813..22007)
                     /locus_tag="VUR46_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET5456678.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFDRKMNKIID"
     gene            complement(22072..23208)
                     /gene="dnaN"
                     /locus_tag="VUR46_001251"
     CDS             complement(22072..23208)
                     /gene="dnaN"
                     /locus_tag="VUR46_001251"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET5456679.1"
                     /translation="MMHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(23367..24728)
                     /gene="dnaA"
                     /locus_tag="VUR46_001252"
     CDS             complement(23367..24728)
                     /gene="dnaA"
                     /locus_tag="VUR46_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET5456680.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(24941..25699)
                     /locus_tag="VUR46_001253"
     CDS             complement(24941..25699)
                     /locus_tag="VUR46_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET5456681.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLAEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(25757..26938)
                     /locus_tag="VUR46_001254"
     CDS             complement(25757..26938)
                     /locus_tag="VUR46_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET5456682.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGEIAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLDKSSGDLE
                     S"
     gene            27121..27600
                     /gene="rlmH"
                     /locus_tag="VUR46_001255"
     CDS             27121..27600
                     /gene="rlmH"
                     /locus_tag="VUR46_001255"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET5456683.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     FTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            27644..27717
                     /locus_tag="VUR46_001256"
     tRNA            27644..27717
                     /locus_tag="VUR46_001256"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27678..27680,aa:Arg,seq:tct)
     gene            27882..28007
                     /gene="comC"
                     /locus_tag="VUR46_001257"
     CDS             27882..28007
                     /gene="comC"
                     /locus_tag="VUR46_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET5456684.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            28028..29353
                     /locus_tag="VUR46_001258"
     CDS             28028..29353
                     /locus_tag="VUR46_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5456685.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            29350..30102
                     /locus_tag="VUR46_001259"
     CDS             29350..30102
                     /locus_tag="VUR46_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456686.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            30154..30225
                     /locus_tag="VUR46_001260"
     tRNA            30154..30225
                     /locus_tag="VUR46_001260"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30187..30189,aa:Glu,seq:ttc)
     gene            30231..30304
                     /locus_tag="VUR46_001261"
     tRNA            30231..30304
                     /locus_tag="VUR46_001261"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30265..30267,aa:Asn,seq:gtt)
     gene            complement(30345..30887)
                     /locus_tag="VUR46_001262"
     CDS             complement(30345..30887)
                     /locus_tag="VUR46_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET5456687.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKARISRS
                     SFYTHYKDKYDMIEYYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            30995..32595
                     /locus_tag="VUR46_001263"
                     /pseudo
     CDS             30995..32595
                     /locus_tag="VUR46_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
BASE COUNT        10384 a         5811 c         5726 g        10689 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccaa ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tcctcttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatt ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccgatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agaatttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagctag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacatgga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catgcttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtaa aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tcttttttat agaagaaaaa tatcaaatgg aatttttttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacaatcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa ttagcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agtgttagcg ttagcattac cgtttcgttt agcaatagct tcctctaata actgcgaata
     6421 caattcaaaa ccaacagaat caatgaaacc agactgggat tttcctaaaa gatttcctgc
     6481 tccacgaatc gaaagatctc gcattgcaat cttaaagcca gagcccaatt ctgtaaatcc
     6541 tttaatcgct tctaatctct tttcagagac ttcactgatt gatttttctg gacgatacat
     6601 gagataagca taagcaatac gattactacg accgactctt cctcttaact gatataaggt
     6661 tgacaagccc atatggtccg cattttcaat aaataaagta ttagcatttg gaatgtccac
     6721 ccctgtctca ataatagtag tcgtcaccaa gatatcgtat tgtccctcaa taaagtctaa
     6781 tagagtattt tccaactgga cttcactcat tcgaccatga acatatccaa tcgaagcctc
     6841 cggaatcaac tcctgtaatt ctgaaacctt ctgaacaatt gtgtcaactt tgttgtaaag
     6901 atagtaaact tgacctccac gctccatttc acgcaagaca gtatcacgaa tgacactatc
     6961 attcttttcc aaaacatagg tctgaacagg atagcgatta gtcggcggag tttcaataac
     7021 agataaatct ctgattccca gcatagacat atggagggta cgagggattg gcgtagcggt
     7081 caaggttagg acatccactt gtttcttcag ttctttcaaa gtttccttat gcttgacacc
     7141 aaatcgctgt tcctcatcaa taatcatcaa gcccaaatca gcaaacacaa catcttttga
     7201 caaaacacga tgtgttccaa tcaaaatatc gacttgaccg tttttcaatt tttcaagtgt
     7261 tgcagtctgc tcttttttac ttctaaagcg actcaacaca tcaacattaa ctgcaaaatt
     7321 ttggaatcgt tccttaaaat tcgtatagtg ctgttgcgct aaaaccgtcg tcggaactag
     7381 aatgacaacc tgtttgtgat cattgactgc tttaaaggct gcacgcatag caacttcagt
     7441 ctttccaaaa ccaacatccc caactaaaag tcgatccatt ggctgagaag cctgcatatc
     7501 cctcttgatt tcctcaatac tacgaagttg atcatccgtt tcaacataag ggaaagcatc
     7561 atcaaaggca tcttgatcat catcatcagc tgagaaagca aaacccttca actgactacg
     7621 ttcagagtag agtttgatta aatcatcagc tatatcctct acctggttct taaccttttg
     7681 cttggccttt ttaaaatgac cgtcatttaa tttattgagt tttggagctt taccatcact
     7741 tgaaatatat ttggacagta gatgaatctg ttccacgggg atagaaattt gatcaccatt
     7801 ttggtattgg acactgacat aatcgcgatg aattcccttg atttcaatgg tttcaattcc
     7861 tagatattga ccaatcccat ggatatgatg gacaacatag tccccttttt caagttcatt
     7921 gtaatctttt aatctctctg catttgaaac atgttgtctt cgaaaacgac gctttaattt
     7981 cttttgaaaa atctcatgtt cagttatcaa taaaatcttt tcatctacaa aatgaaaacc
     8041 atgtctgaga ttaccctcta ttaagtttac agattcttta cagatacttg tcttatctct
     8101 agaatccaat ttaatctgat attcctctaa catatcctcc aatgttttac ttcccattga
     8161 attgctagac tgcagaataa tggtgtaatc cattttttta tatcgttcaa tttcttcttt
     8221 tagaaaagaa aactgattga aaaattcctg cataggatat tgattgaatt gataaatttt
     8281 gtcaaatttg agatttccta aacccttttg aagattagag aaaaaggtca ctggactttg
     8341 ttttttatag atttgttcaa tatcagaaaa atactgcata tcagaaaatg ctttactatt
     8401 ctgtaattct tctgtaaagt actgcgctaa gtctctttca aagacttcat actgattcat
     8461 caatttttga taatcatcaa agaatattgg agtatctttt tcaatataat caaagacagt
     8521 ccatgtctta tcatagcaca aagataaaaa cttccgagag tctgcatgac tttgtttttg
     8581 gtgaaaactt gaaagaattt cttccaggta tgatttcaaa ataggtgata aagtttttga
     8641 aatttgtttt tctaaagctg actgtcctcg ttgataatcc ttttctctca aaagcatatc
     8701 actagctgga aagatagtga gttctgtctt attttctttc gataattgtg tttctacttc
     8761 aaatgacctg ataccatcaa tttcatcacc aaaaaactca attcgacaag gttctaactg
     8821 ggatatttca aaaatatcta aaatatctcc tcgaagacta aattcgccct gagtttgtac
     8881 ttgagtaact tttcgatagc cattttcctt taactgatgg ataaacgcgt gttgatcata
     8941 ttcttcacca actgagattt ttacaatact atctttgaat gcattgggag acggtaaaat
     9001 caatcgactt gctgcgatat tacaaactaa aatccctttc ttagatgaat cagtcaaaaa
     9061 acgcaaggct tcaacccgtg aaataatttt ttcctgtgaa gacatcaaaa actccaccat
     9121 aggagcatca tctaccaaaa atggatagac gagttcctca cccaagatag atataagatc
     9181 actaacaagt ccttctgctt ctccataagt tgacgtcaat aacacaatcc tatcttcttt
     9241 ttctaaactg cttgcaattg caagagcctt agtagatgtt gataaaccaa gtattagttg
     9301 tcttttctta tctgttaaat tttgatgcca ttttttaatc tgatcatttt ctgagaataa
     9361 atctaataag gtcaccattt atccgttata cctctgcatt gttttctcaa aatttttctc
     9421 ttgtaaatag tagtttacag aatcgtcaac tttgtcaaca gactgtaaaa taccgatata
     9481 atcatccctg tcaaacttac tcaaaacatg atgaacaact gacataccat ttttaggtct
     9541 tccaattcca atcttaacac ggttaaagac ctgagttcct atatgttgaa taatagactt
     9601 gataccatta tgaccacctg ctgagccttt tgctcttaaa cgaattttcc caacttccat
     9661 gtcaagatca tcgtaaatga taagtaaatc gtcaatatcc aaaccatagt aagttaataa
     9721 agcatgaact gcttttccac tttcattcat aaaggtcgtt ggtttaacca gataaatttt
     9781 ttctccattt aggaaaaagg atgctaggtc agcttgaaat atcttatcgt gtgtaaaagt
     9841 gacattctgt ttcttcgcta gttgatcaat caacataaaa ccaacattgt gttttgtttc
     9901 aaaatattta tcccctggat ttcccaagcc tacaagtaat ttggtcattt atttttcctt
     9961 tcaaaagcca aaagggttgg aatttttttc caacctaatt gacaccattt attaattttt
    10021 agacattaaa gcggaattcc atgatatcgc catcttgaac gatatattct tttccttctt
    10081 cacgcaagcg tccagcttct tttacggcct tttcagattc gtatttcact agatcctcat
    10141 atgacatggt tactgcacga ataaagcctt tttcaaagtc tgagtggata ataccagctg
    10201 cttgaggagc cttcatacca cgtttgaaag tccaagcgcg aacttctttt tcaccagctg
    10261 tgaagtaagt tcccaatcca agcaagtggt aagctgcacg cgtcaactta tctacacctg
    10321 attctatcaa accaatggct tcaagaaact cttttttatc ttcatcatcc aattcagaaa
    10381 tttcttcctc agcacgcgca gaaataacga ctacttcagc attttctgtc gctgcaaatt
    10441 cacgaatttg tttgacatag tcgatagagt caggttctga aaccacatcc tcgtccacat
    10501 tagctacata aagaactggt ttagtcgtca aaaggaaaag acctttgaca accttttgtt
    10561 cctcatctgt aaattcaatg gtacgagctg atttcccgtc ttctaggact ggtttaatct
    10621 tttgaagaac attgaattct gctactgatt ctttatcttt ttgcgtacgt gccatctttt
    10681 ctacacgcgc atatcgttta ttgactgatt ctaagtctgc aagaatcaat tctaggttaa
    10741 tggtgtcaat atctgcaagt ggatccacaa aggcgtcttc acgtccttgc tcgcgcatta
    10801 cattttcatc atcaaaagca cgaactacgt gaacaatcgc atctacttca cgaatattgg
    10861 ccaagaattt attccctagc ccttctcctt ttgaagctcc ttttacaatc cctgcaatat
    10921 ctgtaaattc aaatgttgtg ggaactgtct ttttaggagt tatcatttca gttagttttt
    10981 gtaggcgttc atctggaact tccaccattc caacatttgg atcaatcgtc gcaaatgggt
    11041 agtttgctgc ctctgctcct gcttttgtaa ttgcattaaa tagtgttgat ttaccaacgt
    11101 ttggcaaacc aacgatacct gctgtcaaag ccatatttct cattctccgt tttcatttca
    11161 atccctaata ttataacaca aaaaggggaa acttgctaaa attccttgat atagctattt
    11221 cccataactg aaataataat tttatggact tttttaggaa ctttttaatt tttcaatagc
    11281 tttttcataa aatgaagtag catttttctg attgtctttg gataggtggc tataaatatc
    11341 catggtcata gaaagttttg catgaccgag ccgtgtttgt atctctttgt aaggtagtcc
    11401 agcattgagc aagatactag catgagtgtg gcggaaggcg tggaacgtaa aacgagggca
    11461 tccagcccgt tccaaatgtt ttactaacct gaaactaagc attctagcgt ctatatgctt
    11521 atcaaagcta ttagagaata ctttctcata ggtcaacccc atttctttcc ctatttggga
    11581 ttgtcttgct ttatagagcc gtagcatgag caccgtctta ttatccaagt caattaccct
    11641 aatacttgat ttagtcttag ggccagtgat ttctttgata atatttaacg ttttatttac
    11701 gtctagtgtg ccgtttttta ggtcaatatc agaccactct aaggctagac actcacgaat
    11761 gcgcaaacca gtcgctaaaa gcgtcttata tagcaccgta tcgtagaaat ttttgtaagt
    11821 gtttggcagc tgctccaggt aagtcaagaa tttttttaag ttatcatcat ccagatattt
    11881 cagtttttgc cctttttttt ccttacgacg tggcacgata atatcacggg cagggttgaa
    11941 ggggatagct tgcaaagata cggcatattt aagtatgcgt ttgtttagcg agtgaaggag
    12001 aggatactct tgaaaccctt tgcctagttg attatagtct tttgcccatt gattgacttg
    12061 cttttgaatg attgggggcg tcagtttatc cagcctataa tttccgaaag ctggaagtag
    12121 atatttatct attttgaatt tggtacccat taaggtcgat tttttaaccg tatggcagta
    12181 ggtttctagc caattctcca ccagttcggc gtaagtcttt atctcaactg ctttatatac
    12241 tgtagacccg tctttttcaa agtcgattta agcctgtagc gctttggctt tgagttctct
    12301 cttggttcgc cctgatatag tcgtcttgac tttcttacct gttacggtat cgataccaag
    12361 gtagacgcta gagcgataga ctgtagaccc gtcttttttg gtgtattctg ttattttcat
    12421 gatgataaac ctttctaaaa tacatcagca ggcaagctat tattaaaaag gttttagatt
    12481 atggtttata tcatgttgag cttacgggaa agattttatt tgttattttc ttcagctaaa
    12541 gctatctgta caagtttttc ttttactttt tcagtgagtt cctcatagta gagaattgaa
    12601 gaaataattt cttttaaaaa attgaaatcg attaacccca ttgctaccca taagacaata
    12661 ttttccattg tttcgataaa gaagggaatg aggtaatcaa ggtgattgat tgttaaaaat
    12721 ttaataccga agacaatgct acttctctta tttccatcat tgaacatatg aaattgaact
    12781 gtattaaata ctagcactgt aagttttgtt tcaaagtctg gatagtaatc gtcattctgt
    12841 aagtgttcaa atacactaaa tacccttccc ttatctttaa caccgtgtaa accacctatt
    12901 ttctcaatta cttcaatgtc gtgtagtaaa attgcttctt cagcagaaaa ataattgatt
    12961 ttatccatta tttatctctc aatctttcaa aaacttggcg gtgttcatca atttgttccg
    13021 aaagtgattt actttgttcg ccaataaatc tttcaaaatc ttcttcagaa attggacgga
    13081 tatattctgc taatttctca tgtttggcat tcctgaaaga tagatcccta ctagccattt
    13141 tctctctggc atgcattaaa tggggttctt gcattgggtg atttgctaat ctctgaatta
    13201 tctcgattac atcagtatta gttagttttt gatttgaaga cttactcttt tgttcaatct
    13261 cataagcaac ccctttttca aaactagcaa taactataag tacctcacta tacattgttg
    13321 cgcgagcatt atcattttta ttcaatttca gtattttttt atattctgat gctctttctt
    13381 taaagattgc tttgtaaatt tcattcgtta attgaccata tttaaaatta cttccagaga
    13441 catacttatc aatggcattt gtaaatattt ttctagcatt atcttcttct aatgcagtcg
    13501 atagataatt tttgtcacgc tggtttataa attttacatg gccaccagtc ttctcagtta
    13561 acacattaat gacaatatca agtagggtat ttcttacttg cttagctata tcactattgg
    13621 ttaacaacat agcaaaatta agcaatgttc tgaacgatga gatacttaat tgtgtaactt
    13681 tgctaccgac atttgtgtcg gtagcaaaag cattttcttt aaatttagct agtttttctc
    13741 cacgtaaagt gtgataacca ttttcagtaa gctccgtttt atgagcttca acaagtcttt
    13801 caatagttcg aatgtcgact tcgaaaaagg tagctagctg agaatttgta aaataaaaag
    13861 tatcctcaaa gtagaaacca ggtactttta aaatctcttc agctttttgt aatgctaaag
    13921 aattatttaa aatattttgt ctttctattt gtgaggttgt cagatcagtc ataatttctc
    13981 ctttttgtcg agttaatttg ccaataactc ccgatatttc aagagtttta ttttattttc
    14041 gtgtcgttag agtatattag aaaatcttga actccgcgaa tacacgcgct tcaggattgt
    14101 tgaacattgt ggcgcgtggg ttagtcgctg aagtgttccc tgatttcttc agctaaatca
    14161 ttcaagcggt tctgaatacc tttatagtaa tcaaattcaa tggtgtcaat gatgtcactt
    14221 ttttcagtaa atatcttgtt ttttgtaaca caaaagctat tatttgtatt attgtgaaca
    14281 aggtcattta tctcattttg aacagaagat attttccttt gtaagcaata gcctaagatt
    14341 tttcgatctt gaatacctat tttttcaatt atttcattca cttcaaagac aactgcccca
    14401 tagctatcaa ttttattgtt aaggctattg ataagattag aaatttcaga atgcacatag
    14461 gaggtattga gagcttgctc acgttcaata acgtttatta aacgtgtaat atattcgtta
    14521 gtaatcatgg tgagtacatt attataagcg tactccctag cttcgcgctg tttggaaagt
    14581 agtagagcct cattattttt tgagatatct gataaatcaa gtccgttgaa aatttcaaca
    14641 ataccagggt ttattattga agactgaaga acgcgaccca aaacaccctg gtcaaatgct
    14701 atttttcctc gaatgtactc catattcata taatcttttt taaagctaag tatttctttg
    14761 attttattga agaacatctc aaaaaccttt tctctttgat tattatctag caactctttt
    14821 agtgtgctgg ttgaaactgt atcaataaac cgcagatcta ggaaagattt ttttacgttc
    14881 aaaaaatcag ctattttttg taaattccca gcggttggta aagattttcc ttttacatat
    14941 cccgtaattg tacttttagg aatatctaaa gcgttatgaa ggtcaatttg tctaacccct
    15001 ttttgttcca taagaaggtt gagccgttta gagaagtatt ctctattttc aagatcttga
    15061 ggactatttt tagccatgac tttaaccctt tcagttgtaa gttatacatt gattataaca
    15121 caaaataaaa acaaagtacg aaaataaata aacttttttt ctaaaaacac ttgactaagt
    15181 acgaaaataa tagtactatt aacttatcac ttttgaaagg aattgttaga ttatatggaa
    15241 caatggacgt tgaaagcctg tagagtaaac gctggttata ctttgcgaca gattgctaaa
    15301 aaggtaaata agaattttca aactgtctcc aagtacgaaa aagatagtac atatataccg
    15361 tttgaacttt taaaagaatt gtctgcaatt taccaagtta aattggacaa tattttttta
    15421 ggagacagta cgaaaaaaat agaactaaat aaaagagagg tgcaataatg agagtattat
    15481 tttaagtcaa tggtggcaga aatcaaacca gacataacaa tagatgaatt attttatagc
    15541 tagaaaggag caaaccaatg gaactagtct acatggacgg aaagaaagag ccgtatacta
    15601 cgagtgagat catcgctgaa tgtgctggag tcactcatca cacaatacaa gaacttttaa
    15661 ggaagcataa agctgatttt gaaagctacg gaattatcgc atttgaaatg cgataattag
    15721 acggccgagg gagaccaatg aaaatatatc tcctaaatga acaacaagcg accttgctga
    15781 tcacttattt aaagaatact gaacctgtac ggcggttcaa aatgaaccta gtcaaagcat
    15841 tctttgaaat gcgtgaggag ctttctaaac gctatcttca aagagaactg gaaaagccaa
    15901 agcgcaagac cttaaccgaa gctatcaaat catgggagaa agcgcccaag catgcctata
    15961 gtacacttac aaacctactg ctaaagggag cgactgggaa aaacaaagcc caactcatgc
    16021 aagagcgaga aagtgaaaac ggtattgaca gtttaacaag cgcggaactg acaaactacc
    16081 aacgtttgga agatatggca atagcgatga ttaacttgaa tagggtgtat tcagaaattg
    16141 aagaactaat ttttaaagca taggagtata gaaaatggaa aatgaattta agacagttac
    16201 aaatgccaaa gggttagaaa ttcctaagta tcccaaggat tttaaaaagc tagttgagat
    16261 ggacagacaa ctagccgaat atctttgtat gaactatgag aacttggaca atgaagacct
    16321 aggcgcattt cttgaaacgg tggagcaggg attcagctgg attctggatc ttatcgaaag
    16381 taaagatttg ctttatagcc cccagacagg gaagaaagca agaaaaagac aataaaaaaa
    16441 gtcacttgct gatagtttgg cgaccgaggc aagcgacaag atttagggta tagatatttt
    16501 ttctatacct agattatagc ataatatagc ggtttccgct agtacattga aaataaaata
    16561 aggtacgctg ggaagatttt aaattttttt cggtttaggg gttgacttaa agggtacacc
    16621 gttacataat aaaagggtac cccgaaagaa agagaggtca aaaatgggga aaacattagg
    16681 acgacctaaa agcgataacc caaaaaacaa gcaactaaaa attaaaatga ctgaacagga
    16741 ttttaataat ttagaagaac ttgccaaaaa gaaaaacatg actaaaacag atatagtcat
    16801 gcgagggatt gagcttgtaa agtctgaacc ataacgaaac cgcctaccgt gtcacttgtt
    16861 tggcgacaga acacgataga cggcgatgca ccacaaatga ggtacgtaaa tatcttatca
    16921 tgcgtactct tatttgtcaa acatagaaat agagtacgct ttttgcgtac ccaaaaatga
    16981 ggtatacaat gagaaagaaa catcaagtag taaaatttaa agatattgct gaaaaattgc
    17041 ctgaattaga gggcaagcgc ctagaagaaa ttactaaagt attaggttac cgtaacctag
    17101 agagttgcag aaccaacctc tgcaagttga aacaaaacaa tcgcctagat tttacactag
    17161 aaaaaggagt ttatagcaag ttcgcactat tagacggtac ggtaaaagag gaattggaag
    17221 ataaagaatt gtcagaacgt gggcgctatt tgaagagtgt agaccgctac aaggcaatgc
    17281 tgaatgcttt ttctatcgcc tttgatagta cggtcaaggc ggaaaccaga caaaaagcag
    17341 aacacgacgg cttgaaagcc ttggacagaa tcccagataa acattacgcc ctactttatg
    17401 acatgatgga gggggaggat ggaagcaaaa acccacttcg ctagattcat gcgtagaggc
    17461 atggagttag caaggcaatt acatagtaaa gaaattcaac gtgatgaatt tgatagagcc
    17521 tggaaaagat taggcgatca aatcgaaaac gaaacgaaga aaaactaaga aaaccgaaga
    17581 gcaggcaagc aattagaaaa ggttttgaaa agcatagagc gccaactctt taaactggta
    17641 ctttctcacg ctttcaattt ggcgagtctg agcgtgaggc atgtgacagg aaaaactgta
    17701 taagaaacaa ccattcaaaa tccccacact caaattttgg ccaaggagag cgtgaggata
    17761 gcaattacaa gaaaaaagca ttaagaagcc atcagggcaa ttacaagaaa aaagcattaa
    17821 gaagccatca gggcaattac acaacataga aacagaggta caagtatgga agaaacaaca
    17881 tacgatatta tcgctaaaag cttggataga attagtatgg aattacacca agctgacgaa
    17941 aataacgatt ttctagaata tgggttttat caggacaatt aaaaggccaa tggaggaaaa
    18001 catgatatca gataaattag aagctatttc aacaaattta gaagaaatac aaaaaagcct
    18061 tgtaggggct gaaactgtat tagctaaaag agaaatcagt agagtgttga acgacttgga
    18121 tgatgtttac agtgaactaa ctagcacaga ataccatgaa caacagcaaa cgataaagga
    18181 acaaacagaa aagatgaaac agagggggat tgctgaggta ataggtgaac tagaagaacg
    18241 agaagagtct tattacagaa atttttgggg tgatactcag tttataaggc tactttccaa
    18301 ctttgatgga tttcttttct taaacactta cctagctgaa ataactaaag aaaataccta
    18361 cccaatggaa caaagtcaat tattgaatta tgtatgggaa gtcatagcgg ttgatatcgc
    18421 aaagaaaaaa cgaggaaaaa agaacgtttt ggattcatgg acagattcat ccttatatac
    18481 tcgtggaatg atgattgatt aggaggcaat gcagtgacac tagacctagg caaaatgaca
    18541 caagcagaat ttgatgaagt aatggctgac atcaaggcaa gaaatccaaa cctattacag
    18601 ctcatcactg attttttaga tagaaaggta acacccgaag aggtggacga cttgttgaat
    18661 atggagcgag ctgaacaagt ggaatatatt aagaattatc aagcgagggc ataacatgaa
    18721 tgaactagat ataagtaaca cacatgctgc tgtcttaatc gtgattttga ttggcttact
    18781 gctttattta aaccaccgag accgcaaaaa aagcgcccaa attgagcgag aaaaccaaca
    18841 gacgataaaa acacctagcg aggatttaaa ccctgattat gggcgatata tccagcttgc
    18901 aggggtaaga gtttccggag ggatggaatg agttacacaa tgaatttata ccccgatatt
    18961 gaaaaaatac cagatgaacc ttattttact aaagatattt ttctagctac gtgtatggac
    19021 aatgcaacaa agttagctgt aactatgagc ttgttgacag aacaaacgtt ggatttagag
    19081 actgagacag ctattttgaa aaccttggat acaatcatag aaactcaaaa agatattttg
    19141 caaggggtag cgagcggaca aataaccttt gtaaataaaa gcaaaggaga ggaggggttg
    19201 gatgagtcta tcagagaatg acaagcgagt tttaagacta atcaaggtag gggctgagaa
    19261 ctccataaca gggtcagaaa ttagcctgac aaccaagcta actgaaagaa ctgtacgtga
    19321 cattatcaag cgtctagtag ttaagcacaa catccctatt gtaggggtta gatgtggcgt
    19381 ttttagtggg tactttattc cagcgaataa aggcgagtta ctagatggcg ctaaggcttt
    19441 ttacaaccaa gtacaggagg agagcaagcg cctagcggtg ttgatgaata gcgacctaga
    19501 aagctacaaa gaaaccttga aggaggtggg cggatatgtt tagcttaagc cgagaaagtg
    19561 agcatgattt gacgcatggc attctggagg tagtggaaag atacctggaa gcgcgtgaga
    19621 aagtaccgcc aagattgacc aagttaataa atagagttga actcaaagaa gagttaaaaa
    19681 ttagtgacaa cacgctgaat aagtgggaaa gtcagggttt aagacgctat caaccaccgg
    19741 acgatggtgc tagaataata ttttatttag tggatgacat tcgtaggttt atgggggtgg
    19801 agaatgggta gatataacac acacccagcg caaggcggag gtcattatca tgacattaaa
    19861 ttgtataagc accgtggcag atctttggaa cagttccaag aacaaaagct actgaagaag
    19921 ttaaaaaaaa cgcaaaaagg ggcgatagta tgacaattta tgaggctaga ggtttccaga
    19981 gtaatcttgt ctatccattt gataagatgg agccgttcca gtacattgaa cgctttaagc
    20041 ctttggtagt ccctgaaggg gcaaacattg aagaatttaa acgtatacaa gcgccttact
    20101 gtattagtgg caaagtgaca ccagaaaaga atggcagtta caagcgaaac aacaccagtc
    20161 taatctatcg ggatttgatt ttccttgatt atgacgatat acaggggacg actgaggatt
    20221 tcatagaagc cgtttctagc gctttgtttg gctactctta tatcttatac ccgactatca
    20281 aacaaggctt atatttagag cttgcagctt tagaaagtgg tattatcaaa aagcaagaac
    20341 taagcaatac cagagtacaa acaagcaggg taaatacgac cgagaataac cttataaatg
    20401 ttctaaaact aaaagagtac actttacaga gaattgagcg acttactgaa gagagaatgg
    20461 aaatatctag gctaatcgat aagctagcca atccgcttga acgttctgtt ctcaggctgt
    20521 tctacttgaa tgttcttgac gcttggcaag ttgctgagga aatagataaa tcaaagactg
    20581 cagtatacat tataaggcaa aaagctatag aacacttagc aaatgtgggg taataggtga
    20641 gcacaaaaaa acgcctagaa caatctaagc gctaaagagt agtggacggt gtgcctgtcc
    20701 cgtcatctca tactatgaag ttgcgtagcg acactatcat ctctacctca cttctcttta
    20761 gactaattat accacaaagg agcgaactaa tggagctgga taagtttaaa acgatgatga
    20821 acgtcagaga acggatgacc tactttctac gtttccagag gatggcaggg agtgaaaacc
    20881 aagttacaat agacgaagag gcttggaaac ttgtcttacc tgatcagtgg aatttgacta
    20941 gtaagcatga aaaagcaatc cgtgaggggt tggaaatatt cgcccaagac atcaacagta
    21001 tagagaacaa acgagctaga aaatacttta ttatccatta ttgttacatg agaaagaaaa
    21061 caatgagcga atgcgtagaa atggcagcta ctagctccac tagctaccac cgatataaac
    21121 aaatagccgt cttaaatttt gcgagaatcc accagaacgg agagctagaa gtgtataagt
    21181 aggcatttgt ggtgttttgt tgagaaatgt tgagatttaa gtgaaggggg atgacatgat
    21241 tgaagatttt ttgattgatt tggataatat ccaattagag gatatggaga tagattttaa
    21301 catggatata gacatcgatt taaacataga ttttgacctt gatggtttag atttgacctt
    21361 actacaagaa ttagaagcgt aaatgttggt aaatgtaggc tgaggcttca tattcgcctc
    21421 cctatttcgc ttggtttcgt cccggacgat taaaacacca tggataaact agaagccctt
    21481 agaaacgaat cagggggact tttgtgaggt cataatctta taaaccacgc gcttcatggt
    21541 ataatatacc tatcagcaac cagcaataaa aaaagcacgt ttgaccgtgc tagtttcttg
    21601 cctgctgaac tcgtcattta ttgccctttt gtggggcttt ttttgtggac tttttgagaa
    21661 tttttaagaa cttttaatga tttctaatca aatgagattt ttcaaaaagt cagtaatatc
    21721 aaaggtttag gcgctataaa caagtttaaa agcgtgtaga ttacaatcta acacaaaaag
    21781 ggataaagtg ctaaccctct aattaagggt tctcagtcaa taattttatt catttttcga
    21841 tcaaaatcat atcgccccat catgacaaca tgctcacaat tactgcattt tattttgata
    21901 tctgctccta cacgtgtaat ttcccaacga ttagcctttt taccagtcga cttgattgta
    21961 caagcgtgtg gttttttcat ctcaacaaaa tttccaactt gatacatact actctccttt
    22021 tctttttcga ttatatcata aaagaggcga gccaggctca acctctttca cttaatttgt
    22081 acgaactggt gtaatgagct gcatgaagtc ttcgtcagta tctgctggca caagagtaaa
    22141 tggacgaaca gctgagataa agctaatggt caccttttcg ctatttaaag ctttaagaga
    22201 atcaatcaag taagttgggt tgaaactaat ggtcaaatct tcaccagtaa cctgatcagt
    22261 atcgatttct tcgtttactt taccaacttc tggagagtga acatgggcgc taacaacccc
    22321 atccttaatt tcaagtttca cagtaccatt ttgagtcgca cttgataaaa gacgggcacg
    22381 ctccattgac tggcgtaagt ttaccacatt aaaagtaata gtagtgttaa agtctgttgg
    22441 aatcaagcga tctgtatcag gatagtttcc ttctaggaga cgagtataga agctaatatt
    22501 ttcgcttcta aagaggattt ggttattggc aaagaaaatt tctacagttt cgatatcatc
    22561 tgtaaatacc gctgaaaatt cgcgtagaga acggctagga attacgacat caaaatcatc
    22621 actatttttt tcaagagtca attttttctg gcttaggcga tgagagtctg ttgcaactgt
    22681 ttttaactct ttgtgttgac tcaatacgaa gtggacacct gttaaaatcg gacgactctc
    22741 ttgtgtactt gcagcaaagg ctgtttcatt aataattttc ttgagtaatt ttgtttcaag
    22801 tattaaagga gtgcttgctg aaatttcttg gattcgtgga tattgttcgc tatcttttcc
    22861 ttttagggta atttctgatt tgccactggt taaaacaatt tgattttgtt caatttcttt
    22921 aaaatcaaga gtcacatcag gtaaactaga tactacattg ataaagaaag aagcttcaag
    22981 aaggatcgaa cctaaagaag taattaacaa accagcatct tcattttttt gagaaataaa
    23041 attttcaatt gaaatttgac catttgaacc aattaaagta ataccttcat tggtcacgtc
    23101 aatttttact gttgataaaa taggaatggc atttttagaa ctaatagctc tcttagtagt
    23161 atttaatgct tgtagaaata aatttttatt aattgaaaaa tgcatcatgg attctccttt
    23221 atttattttt agtattagaa agataatagt aataatagag tctgtgaaat ctgtggaaaa
    23281 cagcctttaa acaagtcata tcaagttttt tagcttgttt aaaaaatgtg gataaaaaag
    23341 ataaaaaagt aaaagttatc cacaaattat ttgattttct ttttgattga ttcaatttct
    23401 aaacgtaaat tatcgtcttg atcaatcaaa gattttattt tggcatgggc atgaatgact
    23461 gtggtatgat cttttccccc aaattccttc ccaatttttg gaagactatt atctgttagt
    23521 tctctagata aatacatggc tacttgacgg gccaaaacaa tattttgaag gcgtctactt
    23581 cccttcattt ctttgatact aacaccataa aagttaccaa cttcagtttg gattttatca
    23641 attgggatga cgagcatttg gctaacatct tgtttgcggg ctctaatggc ttctgcagca
    23701 atatcaatag tgatatcctt gatttttttt actctggcaa ttaaagtgat gtcgttgatg
    23761 gctccctcaa gatctcgaac atttgaatca aattgcccag ctaggtattc tagagtatca
    23821 ctttggaaat tgtagcctaa atgttccgtt ttactttgta aaatggcaat acgtgtttca
    23881 aagtcagggg gtgtgatagt ttgtgtcaat ccccaactaa aacgcgtgac aagcctctcc
    23941 tcgagccctt ctagatgttt tggactacga tcactcgtta ggacaatctg tttttgcttg
    24001 tcatgaaggg cgttaaaggt attgaaaaat tcttcctgag ttgcgacttt ttttccgctg
    24061 agtgactgga tatcatcgat taacaaaaga tcaagactac gataggtctt tttaaacttt
    24121 tccatttccc caagtcttag gtgatcaaga aagtcattaa taaagctttc ggcaggaata
    24181 tatttaacac gcgcattagg aatatttttt agaatttcat ttccaatagc gtttaataag
    24241 tgagtcttac caaggcctgg tcctccatag ataaaaagag ggttataggt cagagctaaa
    24301 tcttcagaga cagctaaagc ggctgataca gcccaaacat ttccatcccc ttgaataaag
    24361 ttatcaaagg tatatttttc ttttaatccc gtatctgaat aaggaataga tactaacttt
    24421 ggactatagt tataaagagt taaatttgta gcttcttcaa cttgtgagct agtcgtatct
    24481 tgaggtttgg tgaaaatata gtggggagtt atttcagcgt cataaatttc aaaaccagct
    24541 actacaataa tatcttttag ttgtttttcc cagaccattt ccatttcaga gcgaggtaga
    24601 aatatagtgg caacattttc ctctaccttg atgagttcag cttgaatagc atagaaatca
    24661 tacatggatc gagtcagtct ttcttgtgca aattctaata tacgattcca aaattgtttt
    24721 tctttcaatc ctttctcctc ctttactatt taaaagttta atactagaga tattttacca
    24781 tagatagcaa gaattttcca caagttgtga aaaataatcc acaatgttac caaactttat
    24841 ccacaggttg gggataaaag aagaaattat tgatttatta agctttttat cgaaaaacat
    24901 agtggataac cttgtgagat aaaaaaataa aagaacagcc ttatttcagg ctgttgataa
    24961 ttctactata ttcttcttga tttgaaaaag aaataatgat ttttccactg tcttttttag
    25021 atagtttaat ttctacatct aatccgagta gttttcttaa ctgtttttct tcattttgta
    25081 tgaaatgatt agttttttgc tgtttctttt gttttttctc tgtcagaaga gcttctaact
    25141 tccttacaga aatatcttct tctataatcc gttgaaagaa atagtcttgt tgttccttat
    25201 ttaatccaac tagggaacgc gcatgggctt gtgatagttt gccattttct acttctgaga
    25261 gaatttgttc tggcaaggaa agtaaacgaa tggagttgct gatatatgga cgagacttgc
    25321 ccattttatc tgcaatttca gcatgggtga atcctttctc tgcgagagat tcataggcgc
    25381 gtgcttcttc tattgggttt aaattttctc tctgtaaatt ttcaataatg gactggacca
    25441 tcatctcttg gtctgaaatc tgtttaacaa cagctgggat agaccgtaga ccagctaaaa
    25501 gtgaagcccg atagcgtctc tctcctgcaa ggatttcata accaataaca ggagattgac
    25561 gaacaataat cggttgaatg accccatttt ctttgataga ttgtgctagt tcatctagtt
    25621 tttctctatc aaattctttt cggggttgat agggattttt ttgtatatct gtgatagaaa
    25681 tcatttcaaa tttttccatg attctacact aacacatctt ttctcttatg taaagctttc
    25741 tttacataga tgtcaattaa gattctaaat cacctgaact cttgtcaagt ttgatagagg
    25801 tagtttcttc tttcccgtta cgatagtagg ttatcttaat ggtgtctccg atagaatggt
    25861 tgtaaagagc actttgtaag tctgttgatg aagcaatctc tttgtcatct acttttgtaa
    25921 tcacatcgta tttttcaagg tgaccattgg caggcatatt actttgtacc gaacgaacaa
    25981 ctacaccaga tgtaacatta cttggaatat tgagtcttct gatgtcgctt gtactcacat
    26041 tagataaatt aaccatctgg attcccaaag ctggacgcgt cacttttccg tttttttcta
    26101 actgttcaat aatattgata gcatcatttg caggaattgc gaaaccaaga ccttctacag
    26161 atgttcctcc atttgtagca attttacttg aggtaattcc gataacctgc ccttgaatat
    26221 tgatcagtgg gccgccagag ttacctgggt taatagcagt atcagtttgg atggcttttg
    26281 tagaaatagc ttgtccatct tccgatttta aggatacatt tctattgaga ctggatacga
    26341 taccttgagt gacagtattt gcatattcag aacctaacgg gctaccgatg gcaatagcaa
    26401 tttctcctac agttaactta ctagaatcac caaactcagc tactgttgtc actttttctg
    26461 aagagatttt gacgacagca atatcagaga aagtgtcagc tccgacaatt tctccaggta
    26521 ctttagtccc atctgacaat cgaatatcta ctttgctggc gccatttata acgtgattgt
    26581 tggtgacgat gtaagcttct ttatcattct ttttataaat aactccagat ccttcactag
    26641 agattcgctg agaatctgtg tcagtatcat cattgccaaa tacgctattt tgtctgtttg
    26701 ccgaataagt aataacagaa acaacagcat cttttacttt gttaacagcc tgtgttgttg
    26761 aattttcgtt cttataggca gtttgtgtaa tagtactatt gttgttagag ttgtttacac
    26821 tacttttttg agttagttga gttattgaaa aactacccaa ggctccacta aaaaagctaa
    26881 tgacgataac gactaataat tgaaaccatt ttttgtaaaa tgtttttaga tgtttcatat
    26941 ttgcctccat atgtttgaat tactgaaagt ataaactgac tagcttaatt ataacttaaa
    27001 cacaaaagtt ttacacaaac tgtggataac tcttttgaaa ctgtgatttt cttaattgaa
    27061 atctattttt tattttgtga ataagatgtg aaaaaataga gaatatgtta gaatagagtc
    27121 atgaaaatta aagttgtaac agttgggaaa ctgaaagaaa agtatttaaa agatggtatc
    27181 gcagagtatt caaaacgaat ttctagattt gctaagtttg aaatgattga gttatcagat
    27241 gaaaaaacac cagataaggc cagtgaatca gaaaatcaaa agattttaga aatagaaggt
    27301 cagagaattt tatcaaaaat tgctgaccgt gatttcgtta ttgtgttagc cattgaaggg
    27361 aaaactttct tctcagaaga atttagtaag cagttagaag aaacttctat aaaaggattt
    27421 tctactttta cttttattat tgggggaagt ttaggattgt catcatctgt aaaaaataga
    27481 gccaatcttt ctgtcagttt tggtcgccta accttgcctc atcagttaat gagactagtt
    27541 cttgttgaac aaatctatcg cgcttttacg attcagcagg gattccccta ccataaatag
    27601 aaaattgact tttaattgaa tttttggtag aataattgtg ttaggtctca tagctcagct
    27661 ggatagagca ttcgccttct aagcgaacgg tcgcaggttc gaatcctgct gggatcaata
    27721 taatagcaaa gctgggaatt ttcccggctt ttttcttaaa aaagtacact ttgggagaaa
    27781 aaaatgacag ttgagagaat tttatctaaa gcgaaattcc attttgtata atggtttttg
    27841 taagttagct tacaagaaaa aacattttag gagattttat tatgaaaaac acagttaaat
    27901 tggaacagtt tgtagctttg aaggaaaaag acttacaaaa gattaaaggt ggggagatga
    27961 ggatttcaag aatcatcctt gattttcttt tcctacgaaa aaagtaatga aataaggaga
    28021 aagagtaatg gatttacttg gatttgggac agttattgtt cattttttaa ttattagtca
    28081 cagttaccgt ttaatttgta aaggtcgaat aaatagaaaa gaattatacg tttttggtgc
    28141 ttatacatta ctaactgaaa tagtacttga attttccttt tatcttctat atttagataa
    28201 aatagggatt gaaagatttt tatttccttt gggcttatat tcctattttc gatggatgaa
    28261 acagtatgag agggatagag gactattcct aagtttacta ctatctcttt tatatgagag
    28321 cactcataac tttctgtccg taactttctc ctctataaca ggagataatt ttgttttaca
    28381 atatcatttc ccattctttt tcgttgtgac ggtgttaacc tattttgtta cattaaaaat
    28441 catttattat ttccatttgg aactagccta ttttgacaag gactaccttt atcctttctt
    28501 gaaaaaagta ttttttgctt tactattgct acatattgta tctttcgttt cagatatggt
    28561 aagtacgatt aaacatttga atagttttgg aagtattttg tcatctattg tctttatctc
    28621 tctccttttg accttctttg caatgaattc tcataaagtt caaatggaga aagagattgc
    28681 tttgaagcag aagaaatttg aacagaaaca tttacagaat tacacagatg aaattgttgg
    28741 tctgtataat gaaatccgtg gttttagaca tgattatgct ggaatgcttg tcagcatgca
    28801 gatggcaatt gacagtggta atttacagga aattgacaga atttacaatg aagttttagt
    28861 caaagcaaat cataaattgc gttcagataa gtacacttac tttgatttga acaacataga
    28921 agactcagct ttacgaagtt tggttgctca gtcaattgtc tatgctcgaa ataatggtgt
    28981 agagtttaca ctggaagtaa aagatacgat taccaagctt ccaattgaac tattggattt
    29041 ggttcgtatc atgagcgttt tattgaataa tgctgtcgaa ggatcggctg atagctataa
    29101 aaagcagatg gaagtagcag ttattaagat ggaaactgaa acagttattg tgattcagaa
    29161 ttcatgtaaa atgacgatga ctccttcagg agatctattt gccttaggat tctccactaa
    29221 gggaagaaat cgcggagtcg gattaaataa tgtgaaagaa ctactagata agtacaacaa
    29281 tattatttta gaaacagaga tggaaggcag tacatttaga caaatcatta gatttaagag
    29341 ggaatttgaa tgaaagtttt aattttagaa gatgttattg aacatcaagt gagactagag
    29401 agaatattgg atgaaatttc gaaagaatcg aatattccaa tatcatacaa gacaacggga
    29461 aaagtccgtg aatttgaaga atacattgaa aatgatgaag taaatcagct ttatttccta
    29521 gatatcgata ttcatggaat tgagaaaaag ggatttgaag tggctcagct cattcgtcat
    29581 tacaatcctt acgctattat cgtctttatc actagtcgat cagagtttgc gactctaacc
    29641 tataaatacc aggtatcagc cctagatttt gttgataagg atatcaatga tgagatgttt
    29701 aagaagagaa ttgagcaaaa tatcttctac acgaagagta tgttacttga aaatgaagat
    29761 gttgtagatt atttcgacta caattacaag ggaaatgatt taaaaattcc ttaccatgat
    29821 attttgtata ttgaaacaac aggggtatct cataaattgc gcattattgg taagaatttt
    29881 gcaaaagagt tttatggtac catgacagat attcaggaaa aggacaaaca tactcagcga
    29941 ttttattctc ctcacaagtc atttttggta aatataggca atatcagaga aattgatcga
    30001 aaaaacttag aaattgtttt ctatgaagac catcgttgtc ctatttcaag attaaaaatt
    30061 agaaaattaa aagatatttt agagaaaaaa tctcaaaagt gattgacaat tagcaagaaa
    30121 ttgatataat ggttatatct gctacagata gaaggtccgt tggtcaaggg gttaagacac
    30181 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatttta tccgccatag
    30241 ctcagttggt agtagcgcat gactgttaat catgatgtcg taggttcgag tcctactggc
    30301 ggagtataga taaaagggaa cacagctgtg ttcctctttt tgtatcaatt tgtatcacca
    30361 agcattttca taaggaagtc tgttatttct tgagaacttt ctttttttcc atgtgcaatc
    30421 caagtttggc agacaccaaa aagtgcatga gttagataga tgctactata ttctaattca
    30481 gtggtattta gattcagttg cataaatcgc ttttgtaaat ctatactgag catgatatga
    30541 agtttatttc gtaagaaatt ttggatttct ttagtcccat tttcagaaag aagggcagcc
    30601 agaagtggtt ctgactctag atattcaaag acttctaaaa tagcgtctct tttgtgatga
    30661 gcatgttttt gaaaaatata ttcaaatgta tggaatagct tgctttgata gtactcaatc
    30721 atatcatact tatccttata gtgagtatag aagctggaac gactaattct ggctttttct
    30781 actaatttga cagtagaaat tttatcaaat ggctgttcca tcagtaattg taccatagca
    30841 ttttcaatag ttcgctttgt ttttaagcgt ttgttacttt cttgcatatt tcctccttgt
    30901 aaacaaatta gactatatgt ctaaaaatag attttttaat gtataatcca ttatatcaaa
    30961 attttagaca atatgtttaa aaaaaggaga aactatgttt aaagaatgga aagcaatttt
    31021 taaaaaacca acctttatta ttgtcataat cgggatttct cttattccag ctctgtacaa
    31081 tatcatattt ttgtcatcaa tgtgggaccc atatgggcaa ttgtctgact tacctgtggc
    31141 agttgtaaat aatgataaag aggcttccta taatggtaat actatggcaa taggaaaaga
    31201 catggtgtcc aatttaaaag aaaataaaac cttggatttt cattttgtag atgaagagga
    31261 aggaaagaag ggattggaag atggcgatta ctatatggta gtgactttac caagtgattt
    31321 atctgaaaaa acaactacat tatccaatat tcaatcgaca gcagcttatc aatcattgac
    31381 aagtgagcaa caaactgaga taagtgattc tgtatctcaa aattttcaat cggctcagtc
    31441 aattgtagct ttagtacaag gtttgcaggg aagtttagaa aacttacaaa atcaatcttc
    31501 taatctttcg actttaaaaa atcaagctaa tcaagtatta cctattactt ctacttcttt
    31561 gataggattg tcaagtggat taacagagat acaaggagct gttactagca aattagttcc
    31621 tgccagtcag tcgattgcat caggtgtaaa cgcatatact acaggtgttg ataaagtttc
    31681 tcagggcgca agtcaactaa gtgaaaaaaa tgccaccttg atacaaaaat cttctagatt
    31741 gacagcagga gttggttaat tacaatcagg atctgggcaa ttagcagaca aatccagtca
    31801 gttactttca ggtgcttctc cattagagaa tagagctaat aaattggcag atggatctgg
    31861 gaaactagca gaaggtggaa caaagttaac ttctggattg gaagatttac agacaggact
    31921 tgcttcttta ggacaaggac taggtaatgc tagtgatcaa ctcaaatcag tatcaacaga
    31981 atctaaaaat gcagagattt tgtcaaatcc actcaatctt tcaaaaacag acaatgatca
    32041 agttcctgta aatggaatcg caatagctcc ttatatgata tcagttgctc tttttgttgc
    32101 agcaatatca acaaatatga tattttcgaa attgccttca ggacgtcatc cagagatccg
    32161 ttgggcttgg ttgaaatctc gatctgaaat aaatggtatt atagctgttt tggcaggaat
    32221 tttggtatat ggaggagttc atcttattgg tttaactgct aatcatgaga tgagaatatt
    32281 tattctcatc atcctaacaa gtttagtatt catgtctatg gtgaccactt taacaacgtg
    32341 gaatagccgt ataggagctt tcttctcact tattttgctt ttactacagt tagcatcaag
    32401 tgcaggtact tatccacttg ctttgacaaa tgatttcttt agatctatta atccctggtt
    32461 accaatgagc tattcagttt cgggattacg acaaacaatc tccatcaaca agtcattttc
    32521 ctagctgtca tactagctct atttactggt ttaggtatac tagcctatca acataagaaa
    32581 atggaagaag attaaaaaaa tcgaccgatt
//
LOCUS       DAVDHZ010000023        32607 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000023 DAVDHZ010000000
VERSION     DAVDHZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.023"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..338
                     /locus_tag="VUR46_001264"
     CDS             <1..338
                     /locus_tag="VUR46_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET5456688.1"
                     /translation="VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIV
                     ICYKATEFSGTLRSSEEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYRHRT
                     EDDWEKKIF"
     gene            complement(335..850)
                     /locus_tag="VUR46_001265"
     CDS             complement(335..850)
                     /locus_tag="VUR46_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET5456689.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALEQLGYLVKD"
     gene            complement(862..1389)
                     /locus_tag="VUR46_001266"
     CDS             complement(862..1389)
                     /locus_tag="VUR46_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5456690.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(1671..2234)
                     /locus_tag="VUR46_001267"
     CDS             complement(1671..2234)
                     /locus_tag="VUR46_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5456691.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(2218..2769)
                     /gene="coaC"
                     /locus_tag="VUR46_001268"
     CDS             complement(2218..2769)
                     /gene="coaC"
                     /locus_tag="VUR46_001268"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET5456692.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(2781..3470)
                     /gene="coaB"
                     /locus_tag="VUR46_001269"
     CDS             complement(2781..3470)
                     /gene="coaB"
                     /locus_tag="VUR46_001269"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET5456693.1"
                     /translation="MKILVTLGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEIQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            3701..5371
                     /locus_tag="VUR46_001270"
     CDS             3701..5371
                     /locus_tag="VUR46_001270"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET5456694.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRAVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVTKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            5699..6874
                     /gene="mutY"
                     /locus_tag="VUR46_001271"
     CDS             5699..6874
                     /gene="mutY"
                     /locus_tag="VUR46_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET5456695.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            6930..7634
                     /locus_tag="VUR46_001272"
     CDS             6930..7634
                     /locus_tag="VUR46_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456696.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            7627..8976
                     /gene="vicK"
                     /locus_tag="VUR46_001273"
     CDS             7627..8976
                     /gene="vicK"
                     /locus_tag="VUR46_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET5456697.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            8978..9787
                     /locus_tag="VUR46_001274"
     CDS             8978..9787
                     /locus_tag="VUR46_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET5456698.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            9878..10120
                     /locus_tag="VUR46_001275"
     CDS             9878..10120
                     /locus_tag="VUR46_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET5456699.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            10122..10376
                     /locus_tag="VUR46_001276"
     CDS             10122..10376
                     /locus_tag="VUR46_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET5456700.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            10423..11199
                     /locus_tag="VUR46_001277"
     CDS             10423..11199
                     /locus_tag="VUR46_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET5456701.1"
                     /translation="MNKKWLFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELHRMIKDLVEKIS"
     gene            complement(11455..12441)
                     /locus_tag="VUR46_001278"
     CDS             complement(11455..12441)
                     /locus_tag="VUR46_001278"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET5456702.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            12635..15103
                     /gene="gyrA"
                     /locus_tag="VUR46_001279"
     CDS             12635..15103
                     /gene="gyrA"
                     /locus_tag="VUR46_001279"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET5456703.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDVVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            15103..15846
                     /gene="srtA"
                     /locus_tag="VUR46_001280"
     CDS             15103..15846
                     /gene="srtA"
                     /locus_tag="VUR46_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET5456704.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            16090..16887
                     /locus_tag="VUR46_001281"
     CDS             16090..16887
                     /locus_tag="VUR46_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET5456705.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVGMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            17035..18294
                     /locus_tag="VUR46_001282"
                     /pseudo
     CDS             17035..18294
                     /locus_tag="VUR46_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            18390..19664
                     /locus_tag="VUR46_001283"
     CDS             18390..19664
                     /locus_tag="VUR46_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET5456706.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            19674..20552
                     /gene="truB"
                     /locus_tag="VUR46_001284"
     CDS             19674..20552
                     /gene="truB"
                     /locus_tag="VUR46_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET5456707.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAIGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSQLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLSPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            20793..21095
                     /locus_tag="VUR46_001285"
     CDS             20793..21095
                     /locus_tag="VUR46_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET5456708.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            21203..21841
                     /gene="udk"
                     /locus_tag="VUR46_001286"
     CDS             21203..21841
                     /gene="udk"
                     /locus_tag="VUR46_001286"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET5456709.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            21969..23309
                     /locus_tag="VUR46_001287"
     CDS             21969..23309
                     /locus_tag="VUR46_001287"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET5456710.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            23287..23499
                     /locus_tag="VUR46_001288"
     CDS             23287..23499
                     /locus_tag="VUR46_001288"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET5456711.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            23496..24371
                     /locus_tag="VUR46_001289"
     CDS             23496..24371
                     /locus_tag="VUR46_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET5456712.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            24364..25179
                     /locus_tag="VUR46_001290"
     CDS             24364..25179
                     /locus_tag="VUR46_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET5456713.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMIQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            25172..25603
                     /locus_tag="VUR46_001291"
     CDS             25172..25603
                     /locus_tag="VUR46_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5456714.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            25610..27277
                     /gene="recN"
                     /locus_tag="VUR46_001292"
     CDS             25610..27277
                     /gene="recN"
                     /locus_tag="VUR46_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET5456715.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKINKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDNVTEAALTQARELLRNREK"
     gene            27279..28007
                     /locus_tag="VUR46_001293"
     CDS             27279..28007
                     /locus_tag="VUR46_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET5456716.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHEAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDSKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHYFIENDGFVAED"
     gene            28086..29909
                     /gene="lepA"
                     /locus_tag="VUR46_001294"
     CDS             28086..29909
                     /gene="lepA"
                     /locus_tag="VUR46_001294"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET5456717.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGDTYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPVINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPEPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNGKTFDVTEVGIFTPKAVDRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAESLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNQTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEE"
     gene            30322..30798
                     /locus_tag="VUR46_001295"
     CDS             30322..30798
                     /locus_tag="VUR46_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5456718.1"
                     /translation="MGLDHFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVYNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEPLYAYIAEAIA"
     gene            30837..31142
                     /locus_tag="VUR46_001296"
     CDS             30837..31142
                     /locus_tag="VUR46_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5456719.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGFDVHCDAVMVKDVN
                     EDLIKGYDIFTPIAATDLGFDPGIPVIEAGLILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            31190..32607
                     /locus_tag="VUR46_001297"
                     /pseudo
     CDS             31190..32607
                     /locus_tag="VUR46_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
BASE COUNT         9811 a         5849 c         7387 g         9560 t
ORIGIN      
        1 atgtagaaaa tgatgaggct tttgcggagt ctgtcattcg tgaaatctac gaagaaacag
       61 ggttgactat ccaaaatcct caacttgtcg gcattaaaaa ttggccacta gatacaggtg
      121 ggcgctacat tgttatttgt tataaggcga ctgagttctc tggtaccctt cgctcttcag
      181 aagagggaga agtttcttgg gtgcaaaaag accagattcc aaacttggat ctggcctatg
      241 atatgctacc tctgatggag atgatggaag ctccggacaa atcagagttt ttctaccgtc
      301 atcgtacaga agacgattgg gaaaagaaaa ttttctaatc ctttactaaa taaccgagct
      361 gctccaaggc ctcctcgata tagtggaggt cttgttgtgt ttcggcttcg actaggtggt
      421 aatggatgcc atctgtcaat tcagatagag gtctaaagtc agaatgctcg acttgttcta
      481 gaaaatgttg cacatctctg cgacaagaca gtttaagcaa ggtttcaatt tctccataaa
      541 cgggatggtc aatcaaggta ttctggacat gcccaccatt atcgacaata gcaaggagtt
      601 cctgaccgat ttcttcaact tcatgtttca ctttgaaaag tttgtgaaca taaggattgg
      661 tatcaatttg cttatagatg tagccacgat tggtggatag gataggagcg ccatcggctc
      721 tcaaaattgc aatgtcctgc acaatgacct gacgtgtgac atgaaaatgt tccgccaaac
      781 tttggccatt aagggcttta ggagcttctt tcaagagttg gagcagggct tgtttgcgat
      841 cttttgtcat agcttttcct tttaacggcg ttttcgaagc actttataga cagctagtgc
      901 taatgtatag tctaccatac tatggataat tgtgccaaat ccaactagca caaatagaac
      961 atagaacatg ttttctacat tggtacccga agttgcgtaa aaaaggacac aggctaatac
     1021 ttcagcaagg gcatgaacaa cagccaaaac aaagttgaaa acccaggaag attttggttt
     1081 atctagggta tcggggaatt tttgtaggta aagagctcct aaagcaccaa aagatatatg
     1141 ggaaaaagcc cgaaaaacga taaccatggg atagccagcc atcaaaaatc caaaactaga
     1201 ggctaggatg acaaaaactg ccatcaaggg cgacaagaac atggctataa aaatagcgat
     1261 gtggctcccc aaagtatagg aagcaggtgg aatgacaatc ttgaaaggca taacaattgg
     1321 aatcaaaatc gcaatagccg ttaaaagggc tgtcattgtc ataaattgtg tctttttccg
     1381 tgtattcaca agaatctcct ttttaactgc atatacacta gtatggtaca ataaaccaga
     1441 caataaagca agaatttact tgggtttata gatcattttt tagttaaaag ttatagtaga
     1501 ttgaaactag aatagtccac ctctacttct aaaacattgt tagaaatcga tttggctgtc
     1561 ctgatcaatt tgtcctgttc ttatttcgtt ttactatagt aaagatttca ttaaaaagaa
     1621 actgtataga gcaaaatctc caccttcagg tttgaaagcg gagattgttt ttattttttc
     1681 aaggtttgta gtcgtggaac aatggctagg gttagaattg cagaaatgac caattcagca
     1741 attgaatttg ttgagataac ggttgccaga agaagttgga tatttccgtt ataaacattt
     1801 ccaaatagga agaagattcc tccaaggaca aagatagtat ttgtcaagga accaagagcc
     1861 ccagctaaaa tcagaccagt cttgtttttc atcagtttat agactaagta aggagttaaa
     1921 ccaatcaaaa tacgtgggac aatggcaatg atagctgagt agatgtttcc gtttggtacg
     1981 aagggagaga agaggtagct tgtcggtaga atcgtaatcg tgttaaccgt caagctaagt
     2041 aatcccatca aaaatccaag tgtaacccca actcgtggac cataaataat gctggcaata
     2101 atgacaggaa tatgaacaat ggtcggtttg attggaaatg gaaaaaggtt aaagataagt
     2161 gagctcagaa agtgtatcac gagcatggta gcaaaaaaga tagcaatggg tgcaatatta
     2221 gagcgttttt tcatcgatag tttcctttat tctttctaaa ataattgtga ggtcagctaa
     2281 agctcctcgt ccgtggtctc cacaagctag tagggattcc ttaggagcaa tcagctgata
     2341 gccgtaggtt tctaatgttt tcagattatt ctgagttact ggatggtcat acatttttgt
     2401 attcatagca ggagctatta gtttgggaat atgacttggt agggctagag ctgtactggt
     2461 taccatgttg tccgcaaatc cgtgagctag ttttgcaata gtgttagcag ttgcaggtac
     2521 cacgataaat aaatctgctt tttttccaag ttcgatatga ttgacctgat caggataggg
     2581 ttctttcatg acatccaagt ggacaggatt ctgtgagagt acctgtagtg tcaaaggttg
     2641 gataaactct gtagcagcct gagtcattaa gacagtgact tgatggcctt gtttttttag
     2701 agaactgact aaatctgccg acttataaga ggcgattgaa cccgttacag ccaagagaat
     2761 gtttgccata gttttccttt ctaagaatga taggcttgaa ttttttcaag gaggagttct
     2821 gcaatttctt ctttagtctg gactgtttga agctgatttt tctcaacaaa tatagctcgg
     2881 tgctgatctg ctgaaatttg agtcaggtca ttcgcgatga ttaaatctgc ttgattcttg
     2941 ataagacttt ttcgtgcaat gtcaaccaga tgatcttcgg taacatcaac cagcagtttg
     3001 aaaccaatca gatgaatagt aggattccat tccttgacta gggatatgat tttgggtgtc
     3061 tttttaagga acaaaacctg aacctcatca gttgaagaaa tcttggcctg atgattctgc
     3121 ttgcttaaaa attcttttag attggagcta gcctgaactt cctcaagccc tgtcatataa
     3181 acaggagtgt agtcagaaac agccattgag tggatcaaga cctgataatc ctgaacacgt
     3241 tcttgtattt ctattagaag gtccttggta ttggtaattt ctcgaatact taggttagga
     3301 tgaggctctg gcttcagagc tcgttttgtc gtaattaaac aaacttcatg ccctgcagaa
     3361 agcaaagtct ctgtgataat tttccccaag tgacctgtag aatggttagt gatagagcgg
     3421 acgctatcga tagcttcact ggtaccgccc aatgtaacta aaattttcat agcactattg
     3481 tacacaaaaa taagcggtaa gtaaaatgaa agtgataaat ttttggtaaa aacgaagatt
     3541 tactatagtt tcaaactata aagccatata aaatttaaga aaggactcta aaagccttaa
     3601 aaaacagaga tatttacgaa cgtttagaga gttttagggt gttaaaaatc ttgttttgtg
     3661 atataatgaa ttatcatata agaggttaga ggaattttga atgaaaacag atattgaaat
     3721 cgcacagagt attgagttga agccaattgt tgatgttgta gagaaacttg gtatttctta
     3781 cgacgatttg gagttgtacg gaaagtacaa ggctaaactc agctttgata aaattcgtgc
     3841 agttgagagc aatccagtcg gtaaattgat cttggttact gccatcaacc caacacctgc
     3901 aggtgaagga aagtcgacgc ttaccattgg tcttgcggat gccttgaaca agattggcaa
     3961 gaaaaccatg attgctatcc gcgaaccgtc tcttggtcca gtcatgggga tcaagggtgg
     4021 tgctgctggc ggtgggtatg cacaagttct gccaatggaa gacatcaacc tccactttac
     4081 tggagatatg catgctatta caactgccaa caatgccctt tctgccttga ttgacaacca
     4141 cttgcaccaa gggaatgagc tgggaattga tcaacgtcgt atcctctgga aacgcgctgt
     4201 ggacttgaac gaccgtgcgc tccgccatgt gactgttggt cttggtggtc ctctaaacgg
     4261 tattccacgt gaggatggtt ttgatattac agttgcttca gaaatcatgg caattctttg
     4321 cttggcaacg gacatcgagg acttgaaacg tcgtttggcg aatatcgtta ttggttatcg
     4381 ctatgaccgt acgcctgttt ctgtaggtga tttgcaggtt gagggtgcct tggctttgat
     4441 tttgaaggat gctattaagc caaacttggt tcagacaatt tacggtacac ctgcctttgt
     4501 acacggtggt ccatttgcca atatcgctca tggatgtaac tctgttttgg cgacgacaac
     4561 agcccttcac ttggctgatt acactgttac tgaagctggt tttggtgcgg accttggtgc
     4621 tgagaaattc cttgatatca agacaccaaa cttgccaaca tctccagatg cagttgttat
     4681 tgtcgcaacc cttcgtgccc ttaagatgaa tggtggtgtg actaaagacg ctctgactga
     4741 agaaaatgta gaggcagttc gtgcaggttt tgctaacttg aaacgccacg ttgaaaatat
     4801 ccgtaagttc ggtattccag cagttgtagc tattaacgaa tttgtatctg atacagaagc
     4861 tgaaattgca gtcttaaaag aactctgtgc ctcaatcgat gtaccagttg aattggctag
     4921 tgtctgggct gatggagcag aaggtggagt agcacttgcc gaaacagttg ttaagacaat
     4981 tgctgaaaat ccagctaact ataaacgttt gtatgataat gacctttctg tccaagaaaa
     5041 gattgaaaaa attgtcactg aaatctatcg tggtagcaaa gtgaactttg agaagaaagc
     5101 tcaaacacaa attgctcaaa tcgttcaaaa cggttgggac aaattgccaa tctgtatggc
     5161 taaaactcaa tacagtttct cagacaatcc aaatgcgctt ggagcaccag aaaactttga
     5221 aattaccatt cgtgaattgg taccaaaatt aggtgcaggc ttcatcgttg ccttaactgg
     5281 tgatgttatg accatgccag gtcttccaaa acgtccagca gctctcaaca tggatgttga
     5341 aagcgatgga actgtactag gcttgttcta gtggattgaa attgacttta agtgagtttg
     5401 gaaataatat ccaagctcat tttttctcag actgcaagca gttcatcaat aagatttata
     5461 ctcttcgaaa atctcttcaa actatgtcag cttcaccttg ccgtaggtat atgatactga
     5521 ctctgtcagt tctatccaca accttaaaac agtgttttga gcaacctgcg gctagcttcc
     5581 taatttgctc tttgattttc attgagtata agtagataga aaagttatat actatctatt
     5641 gaaaatatta taaatcagat acaaagacag gtgaaacctt ctgtgttata ctagagatat
     5701 gttagatttg aaagaatacg gtatcgtcat gtggccggag gagaaagtca tttctttccg
     5761 tgagaaactt ctcgcttggt atgatgaaaa caaaagagat ttgccttgga ggagaagtaa
     5821 aaatccttat cacatctggg tatctgaaat catgcttcag cagaccaggg tggatacagt
     5881 tatcccttac tacgaaagat tcctggactg gtttccaact gtcgaaagtc tggcaactgc
     5941 gcctgaggag agtttactga aagcttggga gggcttgggc tattattctc gagttcgcaa
     6001 tatgcaggct gcagcccagc agattatgac tgactttggt ggccaatttc caaataccta
     6061 cgaaggaatt tccagcttga aagggattgg accttacaca gcaggagcca tttccagtat
     6121 tgcttttaac ttgcctgagc cagctgtaga tggtaatgtc atgcgggtct tggcgcgtct
     6181 gtttgaagtc aaccacgata ttgggattcc aagtaatcga aaaatttttc aggcaatgat
     6241 ggagatcttg attaatccgg atcgtccggg tgattttaat caagccttga tggacttagg
     6301 gtctgatatt gagtctcctg taaatcccag acctgaagaa agcccagtca aggactttag
     6361 tgcggcatat cagaatggaa ccatggaccg ttatccaatt aaatctccta agaaaaagcc
     6421 ggttcctatt tatcttaaag ccttagttgt gaaaaattct caaggacaat ttttacttga
     6481 aaaaaatgaa agcgaaaagc tcttggcagg tttttggcat ttccccttta tagaagttga
     6541 taacttttcg caagaagagc agtttgacct ctttcatcag gttgcggaag aaagtgtgaa
     6601 ctttggtccc agtccagaag agagtttcca gcaggactat gacctagatg ttgattggct
     6661 tgatgtttgt tttgatacag tccagcatgt ttttagtcat cgaaaatggc atgtacagat
     6721 tgtagcaggt caggtgagtg acttccatga tttttcagat agggaagttc gctggctttc
     6781 accagaagaa ttcaagaatt acccacttgc caaaccccaa caaaaaatct ggcaggctta
     6841 tgcacaagcc aacttagaca gtagccaaga ctagctattg tgtcttctga ctattttttt
     6901 ggtataatag tagagaaaaa ggtgaacata tgaaaaaaat actaattgta gatgatgaga
     6961 aaccaatctc ggatattatc aagtttaata tgaccaagga aggttacgaa gttgtaactg
     7021 cttttaatgg tcgtgaagcg ctagagcaat ttgaagcaga gcaaccagat attattattc
     7081 tggatttgat gcttccagaa attgatggtt tagaagttgc taagaccatt cgtaagacaa
     7141 gcagtgtgcc cattcttatg ctttcagcca aagatagtga atttgataag gttatcggtt
     7201 tggaacttgg ggcagatgac tatgtaacga aacccttctc caatcgtgag ttgcaggcgc
     7261 gtgttaaagc tcttctgcgt cgttctcaac ctatgccagt agatggtcag gaagcagata
     7321 gtaaacctca acctatccaa attggggatt tagaaattgt tccagacgcc tacgtggcta
     7381 aaaaatatgg cgaagaacta gacttaaccc atcgtgaatt tgagcttttg tatcatttag
     7441 catcgcatac aggtcaagtc atcacgcgcg aacacttgct tgagactgtc tggggttatg
     7501 actattttgg tgatgtccgt acagttgatg tgactgtacg acgtctgcgt gagaagattg
     7561 aagatacgcc cagccgacca gagtatatct tgacacgccg tggtgtaggg tattacatga
     7621 gaaataatgc ttgatttact gaaacaaacc atttttacca gagattttat ctttatcctg
     7681 attttgttag gtttcatcct tgttgtgacc ctcttattac tggaaaatag acgtgataat
     7741 attcagttga agcaaatcaa tcaaaaggtt aaagatttga ttgcaggaga ttattccaag
     7801 gttcttgata tgcaaggtgg gtctgaaatc accaatatta ccaataattt gaatgacttg
     7861 tcggaggtta ttcgtctcac tcaggaaaat ctagaacaag agagtaagag gctaaatagt
     7921 attctgtttt atatgacaga tggggttctt gcgaccaacc gtcggggtca gattatcatg
     7981 attaacgata cagccaagaa gcaactgggg ttggttaagg aagatgttct gaatagaagc
     8041 attttggaat tgctcaagat agaagaaaac tatgaattgc gtgatttgat tacccaaagt
     8101 ccagaattgt tgctagattc ccaagatatc aatggtgaat atttgaacct tcgagttcgc
     8161 tttgccttga tacgtcgaga gtctggcttt atttcaggtt tggtggctgt tttgcatgat
     8221 acgacggagc aggagaagga agaacgcgaa cgaagactct ttgtttccaa tgttagccat
     8281 gagttacgga ctcctctgac tagcgtaaaa tcctatcttg aagccttgga tgagggggct
     8341 ttgtgtgaaa ctgtagcacc agactttatc aaggtttctc ttgatgagac caaccgtatg
     8401 atgcgcatgg tgacggatct cctccatctt tcacgtattg ataatgctac cagtcaccta
     8461 gatgtggaac tgattaactt cactgctttt attaccttta tcctcaatcg ttttgacaag
     8521 atgaaaggac aggaaaagga gaaaaaatat gagttggtga gagattatcc catcaattct
     8581 atctggatgg aaattgatac agataagatg acgcaggttg tcgacaatat tttaaataat
     8641 gctattaagt attcgccaga tgggggtaaa atcactgtca gaatgaagac aactgaagac
     8701 cagatgattt tatccatttc tgaccacggt ttggggattc ctaagcagga tttaccacgt
     8761 atctttgacc gtttctatcg tgtggatcgt gctagaagtc gtgcacaagg tggtacaggt
     8821 ctaggactgt ctatcgctaa agaaattatc aaacaacata agggctttat ttgggccaag
     8881 agtgaatacg gcaagggttc aacctttacc attgtgctcc cttatgataa ggatgcagtg
     8941 aaagaagaag tatgggagga tgaagtagaa gactagaatg agtgaaatag gctttaaata
     9001 cagtatttta gcgtcgggtt ccagtggaaa ttctttttat ctggaaacct caaaaaagaa
     9061 gcttttagta gatgcaggct tgtctggcaa gaaaattacc agtctgctag ctgaaattaa
     9121 ccgtaagcca gaagacctgg atgccatctt gattacccat gagcattcag atcatatcca
     9181 tggagtaggc gttttggctc gcaagtatgg tatggatctt tatgccaatg aaaagacctg
     9241 gcaagctatg gaaaatagta aatatcttgg caaggtggat tcttcgcaaa agcatatttt
     9301 tgaaatgggt aaaaccaaaa cctttggaga tatcgacatc gagagttttg gtgtaagcca
     9361 tgatgcagtc gcaccgcagt tctatcgctt tatgaaggat gataagagtt ttgtcctttt
     9421 gacagataca ggttatgtca gtgaccgtat ggcgggcatt gtcgaaaatg cggatggcta
     9481 tcttatcgag gccaaccatg atgtagagat tttgcgatca ggttcttacg cttggcgact
     9541 caaacaacga atcctatctg accttggtca cctttctaac gaggacggtg ctgaagctat
     9601 gattcggacg ctaggaaatc gtactaagaa gatttacctt gggcatttat ctaaggaaaa
     9661 taatatcaag gaactggctc atatgaccat ggtcaatcag ctggctcaag ctgatctggg
     9721 agtcggagta gactttaagg tttatgatac ctcaccagat accgcaacac cattgacaga
     9781 gatataaaaa gaacgctgag aaggtgttct ttttatattg actgaacaca taaaaagtaa
     9841 tacaatggtg ttaccattaa aaaagggagc acaaaagatg actactatta cattaaaagt
     9901 ttctgaagct gataaaacat ttatgaaagc aatggctaag tttgaaggag tttccctttc
     9961 ggaacttatt cgcaccaaaa ctcttgaagc cctagaagat gaatacgatg ctcgtgtggc
    10021 agatttagcc tatcaagagt atttagaaga cttggaaaaa ggagttgaac ccattacttg
    10081 ggaagaaatg atgcatgatt taggcttgaa ggatgaataa tttgtataaa ttagttccaa
    10141 caagacgttt tatcaagcaa ttgaaaaaat tggaccgtta tacgcagaag ctaattacaa
    10201 actatttaca aaccaatgtt ttggaagacc caagacgaca cggaaaggct ttggttggta
    10261 atcgcgttgg tcaatggcgc tatagaattg gtaattatcg agttatcgta caaattgtag
    10321 atgatgaatt agtcgttgct actctagaag ttggtcatcg gagagatatt tattgaatta
    10381 aagctgagta ataacagtat agaaagtaag gatagtaaaa atttgaataa aaaatggtta
    10441 tttgcagatt attatgatac aacaattatt ttacttgctt taatctctgt tattctggta
    10501 ttacttggat ttgctgagat gattgatttg gacaatccgc cttatagtat tattgattta
    10561 gtaatctggg gtgtttttgt aattgattat agttggcgct tttttattac taaaagaaaa
    10621 tggcgcttta ttcttgaaaa tatttttgat ttattgacta ttctcccttt aaatgctatt
    10681 tttacagtgt ttcgattagg acgtatcttc cgcttagcaa ggctgacaaa attactgaaa
    10741 ctgactcgtt tacttagaat aattggactt acaggtaaat tagaaagaaa aattagtaga
    10801 ttcttacgga caaatggcct gatttatatc ttatatgtta atatctttat tgttctagta
    10861 gggagttcga ttttatccgt tgttgaagaa aaatccttct cagatagtct ttggtgggct
    10921 cttgtgacag taactactgt tggttatggt gatattgttc cagtttccct ttttgggaaa
    10981 tggctagcag ttttactgat gcttgtcggt attggaacaa tagggatgct aacaagtgct
    11041 ttgacgaact tttttgtaaa ggataatcca gatgaacaga taaaacttga taaactcaaa
    11101 gacgaattat cgagccaaag aatattaata gagaaacaat ctgaaaaaat cgaagaacta
    11161 catcgaatga taaaagactt agttgaaaaa atatcataaa ggtgagacaa aacaaaactt
    11221 gattcgagga gaaatcaagt aagttttgac acaatagaac gcatattatc aggtataaaa
    11281 atttgataat atgcgtttta tagagaaatg aaataaaatt tgaacaaatc aattaggaat
    11341 ttaaagcatt ttataacaac gttttagagt aatggggtgc tatttcaact tcaacctact
    11401 ataatacaga aagaaacaac tccctgatga ttcaaggagt tgtctatagt taaattagtt
    11461 tttagaagct tcttggaatt ctggattttt ccatgcttcg tcaataatag cttgcaattc
    11521 tttagcagat gcttgcattt tttgagtttc tgcatcgttc aatggaatgt ttactggacg
    11581 aacgatacca tgtgcaccaa caacagctgg ttgaccgata aagacattct caactccgta
    11641 ttgaccttct tggaatactg aaagtggaag tactgcgttt tcatcgtcaa ggattgcttt
    11701 agtgatacga gcaagggcta ctgcgatacc gtagtatgtt gcaccttttt tgttgatgat
    11761 tgtgtaggct gcatcacgaa caccttcgaa caattcaatc aattcagctt cttgaacatt
    11821 ttgagtgtct ttaaggaatt cttcaaggtt tacaccagcg atgttagcgt gtgaccaaac
    11881 agcgaactca gagtcaccgt gttcacccat gatgtaggcg tgcactgaac gagcatccac
    11941 atccaatttt tcagcaagtg cttgacggaa acgagctgag tcaagtgaag tacctgaacc
    12001 gataacgcgt tctttaggga aaccagagaa tttccaagtt gagtaagtca aaacgtcaac
    12061 tgggttagca gcaacaagga agataccttt gaaaccagat tcaacaactt gagttacgat
    12121 tgatttgttg atagcaaggt ttttacctac aaggtcaaga cgagtttcac ctggtttttg
    12181 aggtgcacct gcagtgatca caacaaggtc agcgtctgca cagtcagagt attgagctgc
    12241 atagattttt ttaggtgaag tgaaggcaag ggcgtgacta aggtcaagcg catcaccaac
    12301 agctttttca tgcaattgtg gaatttcgat aattccaagc tcttgtgcaa ttccttggtt
    12361 aacaagtgca aaagcgtaag atgaacctac agcaccatca ccgacaagga taactttttt
    12421 gtgttgttta gttgaagtca ttgttttaaa catctcctta attttattag gggattttcc
    12481 ctagacaact tcattctatc acttttaaaa aactttgtca cgaatatgcc ttatagttct
    12541 cgatgtaaac gttttagtgg tttagaggct gaaatagatg ggaatttatg gtataatgtt
    12601 gttacttact aattgtgaaa tgaggcattt attaatgcag gataaaaatt tagtgaatgt
    12661 caatctgaca aaggagatga aggcaagttt tatcgactac gccatgagtg ttatcgtagc
    12721 gcgagctctt cctgatgttc gagatggctt aaaacctgtt caccgtcgca ttctctacgg
    12781 aatgaatgaa ttgggtgtga ccccagacaa accccataaa aaatctgctc gtattacagg
    12841 ggatgtcatg ggtaaatatc acccacacgg ggattcctct atttatgaag ccatggtccg
    12901 tatggctcaa tggtggagct accgttacat gcttgtagat ggtcatggga attttggttc
    12961 tatggatgga gatagtgctg ccgctcaacg ttataccgag gcacgtatga gcaagattgc
    13021 tctggaaatg cttcgtgata tcaacaaaaa tacagttgat ttcgttgata actatgatgc
    13081 caatgaacgg gaacccttgg tcttgccagc gcgttttcca aaccttttgg ttaatggagc
    13141 aactggtatt gcggttggga tggcaaccaa tattccacct cataatctgg gtgaaaccat
    13201 tgatgtagtg aagttggtca tggataatcc tgaagtgact accaaggact tgatggaagt
    13261 cttgcctgga ccagattttc caactggtgc tcttgtcatg gggaaatcag gtatccataa
    13321 ggcttatgaa acaggtaaag gttcgattgt cctacgttct cgtacagaga ttgaaacgac
    13381 taagactggt cgtgagcgca tcgttgtaac agaatttcct tacatggtca ataaaaccaa
    13441 ggtgcatgag catattgttc gcttggttca ggaaaaacgc attgagggta tcacagcagt
    13501 acgtgatgag tcaaaccgtg aaggtgttcg atttgttatt gaagtcaagc gcgacgcctc
    13561 agccaatgtt attctcaata acctcttcaa aatgacccaa atgcaaacca attttggttt
    13621 caatatgctc gctatccaaa atggtatacc gaaaattttg tctcttcgtc agattttgga
    13681 tgcttatatc gagcaccaaa aagaagtggt tgttcgtcgt acacgttttg ataaggaaaa
    13741 agcggaagcg cgcgctcata tcttagaagg tctcttgatt gcgctagacc atatcgacga
    13801 agtgattcgt atcatccgtg ctagtgaaac ggatgcggaa gctcaagctg agttgatgag
    13861 caagtttaag ctttctgaac gtcaaagtca agctatcctt gatatgcgtc ttcgtcgttt
    13921 gacaggtttg gaacgcgata agattcaatc tgagtatgat gacctcttgg ctctgattgc
    13981 ggatttagca gatattcttg ctaagcctga acgtgtttct caaattatca aagacgaatt
    14041 ggatgaagtt aaacgtaaat tttctgataa acgccgtaca gagttgatgg ttggacagat
    14101 cttgagtctc gaggatgagg acttgattga agaatcggat gtcttgatta ccctttctaa
    14161 cagaggctac attaagcgtt tggatcagga cgagttcact gctcaaaaac gtgggggtcg
    14221 tggtgtccaa ggaacgggag tgaaagatga tgactttgtt cgtgagttag tgtcaactag
    14281 cacccatgat catctgctct tcttcacaaa caagggacgt gtctatcgtc ttaaaggtta
    14341 tgaaattcct gagtatggtc ggactgccaa agggctacca gtagtcaatc tcttgaaatt
    14401 ggatgaagac gaaagtattc agacggttat caatgttgag tctgatcgca gtgatgatgc
    14461 ttatctcttc tttacaaccc gtcacggtat tgtgaagaga accagtgtta aggagtttgc
    14521 caatattcgt caaaatggtc tcaaagcgct gaatttaaag gatgaagatg agttaatcaa
    14581 tgtcttgttg gcagaaggag atatggatat tatcattggt accaagtttg gttatgcagt
    14641 tcgctttaat caatcagccg ttcgtggtat gagtcgtatc gccactggtg tgaaaggtgt
    14701 taaccttcgt gaaggagaca cagttgttgg tgccagcttg attactgatc aagatgaggt
    14761 tcttattatc acagaaaaag gatatggtaa gcgtacagtc gctactgaat acccaacaaa
    14821 aggtcgtggt ggtaagggaa tgcagacagc taaaattacc gaaaaaaatg gcttgctggc
    14881 cggtcttatg actgttcaag gggatgagga tttgatgatt atcactgata caggtgtcat
    14941 gattcgaacc aatcttgcca atatttcaca aacaggacgt gcaactatgg gagttaaagt
    15001 aatgcgcctg gatcaagatg ctcagatagt gactttcaca acggttgcgg tggcagaaaa
    15061 agaagaagtt gggacagaaa atgaaacaga aggtgaagca taatgtctca aaaaaataat
    15121 aaaaagaaaa acaagcgaaa aaatctgctg acaaatatcc tagcaggatt tctgatatta
    15181 ctgtcactgg ctttgatttt taatactcaa attcgaaata ttttcatagt ctggaatacc
    15241 aataagtatc aagttagcca ggtatcaaaa gagaaattag aagaaaatca ggatacagaa
    15301 ggcaattttg actttgattc tgtcaaagct atctcttcgg aagctgttct aacttctcaa
    15361 tgggatgctc aaaaattacc agttattggg ggaattgcaa ttcctgaatt ggaaatgaat
    15421 ttgccgattt ttaaaggact tgataatgtt aatctcttct acggagctgg tacaatgaaa
    15481 cgcgagcaag taatgggaga aggaaattat agtctagcta gtcaccatat ctttggtgtt
    15541 gataatgcta ataaaatgtt attttctcct ttagataatg ctaaaaatgg catgaagatt
    15601 tatctaaccg ataaaaataa agtttatact tatgaaatac gtgaagtcaa acgtgtgaca
    15661 ccggatcgtg ttgatgaagt tgatgataga gatggggtca atgaaatcac attagtaacc
    15721 tgtgaagacc ttgctgctac agaacgtatt attgtcaaag gtgatttgaa agaaacaaaa
    15781 gattattcac aaacatctga tgaaatccta acagctttca atcaaccata taaacaattt
    15841 tattaataca aatcagtgaa atcatggatt tcactgattt tttaagattt tcataaaaat
    15901 atagtaaaat gaaataagaa taggacgaat cgatcaggac agtcaaatcg atttctaaca
    15961 atgttttaga agtagaggtg tactattcta gtttcaatct actataaact tttatgaaat
    16021 atagaaaacg cttcctaaaa cctaaagttt gtgatataat tatcaagaaa aaagatttag
    16081 gagtttatta tggtttcttc agaatttatc tcaaagattg aatttgcttg caataagaaa
    16141 gaaagtcttt atagtcaaag caaatttaag tatgcgattc gttcgatgtt cgcaggtgca
    16201 tttttaacct tcagtactgc tgcaggtgca gttggggctg acttgattaa taaaattgca
    16261 ccaggtagtg gacgcttcct ctttccattc gtttttgctt ggggcttggc ctacattgtt
    16321 tttttgaatg ccgagttggt cacttcaaac atgatgttct tgactgctgg tagtttctta
    16381 aaaaaaatct cttggagaaa aacagctgag attttactat actgtacctt gttcaacctt
    16441 atcggagcct tgatagcagg gtggggcttt gctcattcgg cagcctatgc gaatctgaca
    16501 cacgatagtt tcatctcagg tgttgttggg atgaagttag gccgctcaaa tgaattggtc
    16561 ttgcttgagg cgattttggc aaatattttc gtaaatattg cgattctgtc atttattttg
    16621 gtcaaagatg gtggtgccaa actttggctt gtgttgtcag ctatttacat gtttgtattc
    16681 ttaacaaacg agcacattgc ggcgaacttt gcttctttcg cgattgtgaa attcagtgtt
    16741 gctgcggatt caattgccaa cttcggtgtt ggaaatatgc ttcgccactg gggtgtgact
    16801 ttcatcggaa actttatcgg aggaggcctc ttgatgggtc ttccatatgc cttcctcaat
    16861 aaaaacgaag atacttatgt agattaagaa aatgagcacg attgagtcgt gcttttttca
    16921 ttttcaaaat aaggtaatag ctatttctta tatcaaaata tagaaaactg atatttgtaa
    16981 actataactc aaggtgctac aatatcctta ataaaataat atggaggtca ccttatgact
    17041 cgtgatttta aatttgaaac tctacaacta catgctggtc aagttgtggc tccagctact
    17101 aagtctcgtg cagtgccgat ttatcaaaca acattttttg tttttgatga cacgtaggaa
    17161 ggtgccgatc tgtttgcctt gaggaaatca gggaacattt atactcgtat caccaatcct
    17221 acaacagctg cccttgaagg tggtgttgaa gcgctagcaa cagcatcagg tatgactgca
    17281 gtgacttata cgattttggc gcttgcccat gctggtgagc atgtagtggc tgcttcgact
    17341 atttacggtg gaaccttcaa tcttttgaaa gaaccccttc ctcgttatgg tatcacaaca
    17401 acctttgtcg atgttgataa tttggaggaa gtagaagcag ctatcaaaga caataccaag
    17461 cttgtcttga ttgaaacctt gggtaacccc ttgattaata ttccagacct ggaaaaactg
    17521 gcagagattg ctcataaaca tcaaatccca cttgtgtcag acaatacttt tgcaacacct
    17581 tatttgatta acgtcttctc tcatggcgtt gacattgcca ttcactctgc gactaagttt
    17641 atcggtgggc atggtacaac tattggagga ataattgtcg atagtggtcg ttttgactgg
    17701 acggcttcag ggaaattccc tcaatttgtt gacgagagtc caagctgcca caatttgagc
    17761 tatactcatg atgtgggtgc agcagccttt attatagctg ttcgagttca attgcttcgt
    17821 gatacaggtg cagccttgtc accattcaat gctttcctct tgctacaaag acttgaaacc
    17881 ctttcacttc gtgtggaacg ccatgtacaa aatgctgaga caattgttga ttttcttgtc
    17941 aaccatccta aggtagaaaa ggtaaattat ccaaaacttg cagatagtcc ttattatgcc
    18001 ttggctgaga aatacttgcc aaaaggtgtc ggttcaatct ttaccttcca cgtcaaaggt
    18061 gacgaggagg aagcacgcaa ggtcattgat aatttagaaa tcttttctga ccttgcaaac
    18121 gcggcagatg ctaaatcgct tgttgtccat ccagcaacaa tcactcacgg tcaattgtca
    18181 gaaaaagacc tagaagcagc aggtgtcaca ccaaatcaaa tccacttgtc tatcggtctt
    18241 gaaaatgtag aagatttgat tgaagactta cgcttggcct tggaaaaaat ttaaagtaaa
    18301 agaagataaa cagtgggttt tgactcactg tttttgattt tccctcaggc atgatataat
    18361 ggttacagaa gtctagaaag aggaatgtaa tgaacgaaat caaatgtccc aactgtgggg
    18421 aagtctttac agtaaatgaa agccagtatg ctgaactttt gtcccaagtg agaacggcag
    18481 agtttgataa ggaactacac gataggatga ggcaggaact ggccttggct gagcaaaagg
    18541 ctatgaatga gcaacagact aaactggctc agaaggatca agaaattgcg caattgcaga
    18601 gtcaaatcca aaactttgat acagaaaaag aattggccaa gaaagaagtt gaacagacaa
    18661 gccatcaggc cttattggct aaggacaagg aagtacaggc cttggaaaac cagttggcga
    18721 ccttgcgttt ggagcatgaa aatcaattgc aaaagaccct ttctgaccta gaaaaagaac
    18781 gcaatcaggt caaaaatcag ctcctactgc aagaaaagga aaatgagttg tctttggctt
    18841 ctgttaagca aaactacgaa gcccagctca aagcagccag tgaacaagtc gagttttata
    18901 agaattttaa ggctcaacaa tctacaaaag cgattgggga aagcctagaa cagtatgcag
    18961 agagtgagtt taacaaggtt cgtagtttcg cctttccaaa tgcttacttt gagaaggata
    19021 acaaggtctc ttcgcgtggg tctaaagggg actttatctt ccgtgagtgt gatgaaaatg
    19081 gagttgaaat catttctatc atgtttgaga tgaaaaacga agcggacgga acagagaaga
    19141 agcacaagaa tgcagatttt tacaaggaat tggacaagga ccgtcgggag aagaactgtg
    19201 agtatgccgt tttggtgacc atgcttgagg ctgataatga ctactttaac acagggattg
    19261 ttgacgtcag tcacgagtat gaaaaaatgt atgttgttcg tcctcaattc tttatccaat
    19321 tgattggtct cttacgtaat gcggcgctaa attccctaaa atacaagcag gagttggcct
    19381 tggttcgcga gcaaaatatt gacattacgc attttgagga agacttggat gcctttaagc
    19441 tagcttttgc taagaactat aattcagctt cgactaactt tggaaaagct attgatgaaa
    19501 tcgacaaggc catcaaacgc atggaagagg ttaagaaatt cctgactaca tctgaaaacc
    19561 aactccgtct agctaacaac aaattggaag atgtctctgt taaaaaattg acccggaaaa
    19621 atccaaccat gaaagcgaaa tttgaagcat tgaaggggga gtagaaagca aaaatgaacg
    19681 gtattatcaa cttaaaaaaa gaagcaggaa tgacctcgca tgatgcggtt tttaaactgc
    19741 gtaagatttt gggcaccaag aaaattggtc atggtgggac cttggatcca gatgtagtgg
    19801 gtgttttgcc cattgcgatt ggcaaggcga cccgcatggt tgagtttatg caggacgagg
    19861 gtaaaatcta tgagggggaa atcactctgg gctattccac gacgactgag gatgctagtg
    19921 gggaagtggt cgcagaaacc cctgttttgt ctcccttgga tgaaaagctt gttgatgaag
    19981 cgattgcgag cttgactggg cctattaccc agattccccc tatgtattcg gcagttaagg
    20041 ttaatggtcg caagctctat gagtatgcgc gtgctggtca ggaagtggag cgtccagaac
    20101 gtcaggtgac catttatcaa tttgagcgaa caagtccgat ttcttatgat ggccaacttg
    20161 cccgattcac ttttcgtgta aaatgcagta aagggactta catccgtact ttgtcagttg
    20221 atttgggtga aaagcttggt tatgcggctc atatgtctca gttaactcgt actagtgctg
    20281 ctggcttaca attagaagac gcactgacct tggaggaaat tgctgaaaaa gtagaggctg
    20341 ggcaattaga ttttctccat cctttagaga ttgggacagg tgatcttgtc aaagttttcc
    20401 taagtccaga agaagctaca gaagttcgct ttggtcgttt tattgagcta gaccaaacgg
    20461 acaaagaact ggctgccttt gaagatgata aattgttagc cattctagaa aaacgaggca
    20521 atctctataa gccaaggaag gtttttagct agattgttta ggaataaaaa tcgggtgata
    20581 gataacaatt gcttgataaa accccatact aatagtagaa tagttttggg aattataata
    20641 ttccaattgt tgcgagttgt agatactcaa ataatctata tagaaattta gaggtgtgaa
    20701 atgaagcaac ttaaaattct ttcagataaa tatttagagt ccattacagg ttctggtggg
    20761 aacttaggcc caggatttgg tgtgataatt ccatgatgcg aaatgagttt cgagaaaggg
    20821 tggagcaact tcttcaacaa aaagaaataa atgaaaatag tgagttgagt cacctgtttc
    20881 gtcttgctat acaaaattta gacagaaatg aaaaatacca atcggtcatg gccaatttga
    20941 gtcaagggtt gtcactttac ctcatgacgc atcattacca ggcacctaag tctgtcattg
    21001 attttggttt atggattgcc aaagctccta gccaggaaag agggagactg gctttcttgc
    21061 agatgcttgc tcaaacccta cagggctttc gttaaaactg tcgaacatca gagggaagac
    21121 tctggtgttt tttgctgatg agactataaa ttttgtaaaa aatgtgatag aatagacgac
    21181 ggataaaata acggaggata gcatgcaaaa tagaccaatc attattggag tgacaggtgg
    21241 ttctggtggt ggtaaaacca gtgtttcaag agccatttta tcgcattttc ctgatgaaaa
    21301 gatttccatg attgagcatg attcatacta caaggatcag tctcatttga cctttgaaga
    21361 gcgtgtcaaa accaactatg accatccttt tgcctttgat acagacttga tgatcgagca
    21421 gattaaggaa ttgttggcag ggcgtccggt ggacatcccg acctacgact atacagagca
    21481 tacacggagt agcaagacct atcgtcagga gcctcaagat gtctttatcg ttgagggcat
    21541 tttggtcttg gaggacaagc gtctgcgcga tttgatggat atcaagattt ttgtggatac
    21601 ggatgacgat gtgcgcatta ttcgtcgtat caagcgtgat atggaggagc gtggccgtag
    21661 ccttgatagc gttattaacc agtacttagg tgtggtcaaa ccaatgtacc accagtttat
    21721 cgagtcaact aagcgttatg ctgatatcgt cattcctgaa ggggttagca ataccgtggc
    21781 tatcgacctg ttgacgacca agattgcaaa gattttggaa gaagctcgaa acagcaaata
    21841 atcacatgtg gaggccttgc ctcctttttc tatttttccc tcataatggt acataaatgg
    21901 agatttttag gcatattttt ggtataataa tacccatgaa agagcaagta aatgaatagt
    21961 aggtggagat ggaaaagtat ttatcggtaa caactttgac caagtatctg aaaatgaaat
    22021 tcgataaaga cccatacttg gaacgggtct atttaactgg tcaagtttcc aactttcgta
    22081 aacgacctac tcaccaatat ttctccctaa aggatgacca tgcagttatt caagcgacca
    22141 tctggtctgg gatttatcag aaattagggt ttgacctgga agaaggaatg aagatcaatg
    22201 tgattgggcg tgtacaggtc tatgaaccaa gtggtagcta ctccatcatc attgaaaaag
    22261 ctgagcctga tggggttggg gcgcttgcga ttcagtttga acaacttaag aaaaaattga
    22321 cagaagaagg cctgtttcaa gaacgcttca agcaagctct accccaattt tctaagagaa
    22381 ttggggtagt aaccagccgt agtggagccg ttattcgaga tattatcacg accgtcagca
    22441 ggcgattccc aggtgttgac atccttcttt atccgaccaa ggttcaaggt gaaggggctg
    22501 cggaggaaat tgcaagaaat attgcgcgtg ctaatcaacg ggacgatttg gatttgctca
    22561 ttattggtcg tggaggtggt tctattgagg atctctgggc ctttaacgaa gaaattgtgg
    22621 tacgagctat ttttgaatct cgtttgccag ttatctctag tgtggggcat gagacggatg
    22681 tgaccttggc agattttgtg gcagatcgac gcgctgcaac gccaacagcg gcggctgaac
    22741 tggcaacacc tgtgaccaag ttggatgtat taactcattt gcaaaatcag gaaaaacgga
    22801 tggcaacggc agtccgaaat gttctatcta agaaacaaga ggctttgaaa aaatgcagtc
    22861 agtctgttat ctttagacaa cctgagcgct tgtatgacgg ttatttgcaa cgcttggacc
    22921 aactgcaact gcgtttgaaa caaagtttgc gaactcggat ttctgataac aaacaattag
    22981 ttcaagcaag aactcatcaa ttagtacaat tatcacctgt taccaaaatc caacgctatc
    23041 aagaccgttt aggacagttg gacaagctct taggtagcca aatggcgtta gtttatgacg
    23101 ccaaggttgc tgaggccaag cgactttcgg aagctttgct catgttggat actagccgaa
    23161 tcgtggcgcg tggttatgct attgtcaaaa aagaagagtc cgttgtagat tcggttgaga
    23221 gtttgaagaa aaaagaccaa gtaacgcttt tgatgcgaga tggtcaagta gaattagagg
    23281 ttaaagatgt caaaacaaaa gaaatttgag gaaaatctag cagaactgga aaccattgtc
    23341 caaagtttgg aaaatggtga aattgctctg gaagatgcga ttactgcctt tcaaaagggc
    23401 atggtcttgt caaaagagct ccaagctacg ctggacaagg ctgaaaagac cttggtcaag
    23461 gtcatgcaag aagacggaac agaaagtgat tttgaatgaa aaagcaagaa aaattagctc
    23521 ttgtcgagtc ggctttggaa gatttttatg gagaccagca gtttgcctct agtttacggg
    23581 agtctgttct ctattctatt catgctggtg gcaagcgtat tcggcctttt ctcttgttag
    23641 aagttctgga agccttgcag gttaccatca aacctgctca cgcgcaggta gctactgcct
    23701 tggagatgat tcatacaggg agcttgattc acgatgacct tcctgctatg gatgatgacg
    23761 attatcgaag agggcggtta accaatcaca agaaattcgg tgaagctatg gccattttgg
    23821 ctggagatgc cttattctta gacccatatg ccttgattgc gcaggcagat ttgccaagtc
    23881 agatcaaggt ggacttgatt gccaacttat cccttgcttc aggtagtctg ggtatggtgg
    23941 cagggcaagt tttggatatg gagggcgaac accagcactt gtctctggaa gaacttcaga
    24001 ctattcatgc caataagact gggaagttac tagcctatcc tttccaagcg gcagctatta
    24061 tagctgaatt gtcacctgaa atgcaggtga agctgaaaac tgtgggtgaa ttgattggac
    24121 ttgcttttca agtcagagat gatgtactgg atgtgacagc tagttttgag gaaatcggca
    24181 agacacctca aaaggatctg caggcagaaa aatcaaccta tcctgccttg ttgggcttgg
    24241 aagagtccat tgccttttgt aaccaaaccc tggatcaagc taatgaaaaa ttagaagaaa
    24301 ttgcccagca gcttcccttt gaaacagaat cgattgtaag tgtagtagaa agtttgagaa
    24361 tcaatggcta aggaaagagt ggatgtacta gcttataaac aggggttgtt tgaaacgaga
    24421 gagcaggcca agcgaggtgt gatggctggc ctagtcgtag cagtccttaa tggagaacgg
    24481 tttgacaagc caggagagaa aattccagat gacaccgaat taaaactcaa gggggagaaa
    24541 ctcaagtatg tcagccgtgg tggtttgaaa ctggaaaagg ccttgcaggt ctttgatttg
    24601 tcggtggatg gcgcgactac gattgatatc ggggcctcta ctggaggttt taccgatgtc
    24661 atgatacaga atagtgccaa gttggtcttt gcagtcgatg ttggtaccaa tcagttggct
    24721 tggaaattac gccaagaccc acgagttgtc agcatggagc agttcaattt tcgctatgct
    24781 gaaaagactg atttcgagca ggagccgagc tttgccagta ttgatgtgag tttcatttcc
    24841 cttagtctga ttttgccagc cttgcaccgt gtcttggctg atcaaggtca ggtggtagca
    24901 cttgtcaaac ctcagtttga ggcaggacgt gagcagattg ggaaaaatgg aattattcga
    24961 gatgctaagg ttcatcagaa tgtccttgaa tctgtaacag ctatggcagt agaggcaggt
    25021 ttttcagtcc ttggcttgga cttttctccc atccaaggtg gacatggaaa tattgaattt
    25081 ttagcgtatt tgaaaaaaga aaagtcagca agcaatcaga ttcttgctga gattaaagaa
    25141 gcagtagaga gggcgcatag tcaatttaaa aatgaataaa aaagaaagac ttgaaaaaat
    25201 tagaagattg gtgacagatt atcaaatcgg cacgcaagaa gaaattgtag aacatttgaa
    25261 agaagcaggt atcactgcca ctcaggcgac ggtatcccga gatatcaaag agttaggtat
    25321 tgtcaaaatt cctttgagag acaacaccta tgtctacgaa ttaccaaaat caatcgtaaa
    25381 aagtctgcaa ctggctgaag acaatatcga atcggctgaa ttgatggata agatgatcaa
    25441 tctccaagtt attccaggaa atacggcttt tgtaaaagct cagttaatcg agacttttgc
    25501 agacaagatt tttagctgtt tgactgatga tagctcgatt ttagtcattg ccagaagtgg
    25561 aagtctagca gaggaaatct ttgaacaagt aaaaaattgg taggtctata tgttacttga
    25621 aatttcgata aaaaactttg ccattattga agctatttcc ctcaattttg aaaaggggat
    25681 gactgtcctg actggtgaaa cgggtgcagg gaagtcgatt atcattgatg ccatgaatat
    25741 gatgttggga gctcgtgcga cgacagatgt tattcgtcat ggtgcaccaa aggcagagat
    25801 tgaggggctt ttctcagttg agaatagtcg tcttttacag gaaatttttg atgagcaagg
    25861 tttagaatta ggtgatgaaa ttatcatccg tcgggaaatc ttgcaaaatg gtcgtagtat
    25921 cagccgtgta aatggtcaga tggttaatct gtctgttttg cgagctattg ggcaacatct
    25981 tgtagatatt catggtcagc atgaccatga ggagttaatg cgtccccaac tgcatatcca
    26041 gatgttggat gaatttggtg atgccgcttt ttgggacttg aaagaaacct atcaaacgag
    26101 ttttgatgcc tatcggaaaa tgcgcaagca ggttctggaa gtcaagaaaa accaacagga
    26161 acacaaggaa cgtatcgaaa tgttggaatt tcaaatggca gagattgagg cagcaaactt
    26221 gcaggctgga gaagacttgg ctctcaacca agagcgagat aaactcctca accacaaaaa
    26281 tattgcggat acactgacca atgcctacag tatgttggac aatgaagatt tttcaagtct
    26341 ggccaatgtt cgttcagcta tgaatgacat ggaaagtgtc gaagagtatg atcctgaata
    26401 ccgtgaaatt tcaagctctc tgtctgagac ctactatgtt ttagaagaca ttagcaaacg
    26461 tttggaagct atcattgagg accttgattt tgatggcaat cgcctcatgc aggttgagaa
    26521 tcgtttggac ctccttcata ctattactcg taagtatggt ggaactgttg atgatgtttt
    26581 gctttatttt gccaagatta cggaagaata caatctcttg acaggcaata atctttcgtc
    26641 tgaggacatg gaagcagagc ttaagaagtt ggaagtcaat cttgtcaatt tggcaggtca
    26701 acttgcttct gctcgtcata atttagctca gcaactcgaa gctgagatta aacaagaact
    26761 gcaagatctt tatatggaaa aagcccagtt tcaggttcgt tttagtaagg gaaaattcag
    26821 tcgtgaggga aatgaaatgg ttgagtttta tatttcaacc aaccctggag aagactttaa
    26881 acccttggtt aaggttgctt ctggagggga attatctcgt ctcatgttag ccattaagtc
    26941 tgccttttca cgtaaagaag gcaagactag cattgtcttt gatgaggtgg atacgggagt
    27001 ttcaggtcgt gttgctcaag ctattgctca gaaaattaat aaaattggtc agcatggtca
    27061 ggttttggct atctcccatt tgccacaagt aattgcgatt gcagattatc aattctttat
    27121 tgagaagatt agtaatgacc attcaacggt ttcgactgtt cgtcttttga cggtcgaaga
    27181 gcgagtggag gaagttgcca agatgttggc aggtgataat gtgacagaag cagccctgac
    27241 gcaagccaga gaattgttga gaaacaggga gaaataagat gacagattat tatgtaattg
    27301 gagatgttca cggaaaagct gggatgctgg aagaccttct caaaacctgg gatggtcagc
    27361 cccagttgct ctttctaggt gatttgattg acagaggtga ggatagtcac cgtgttcttg
    27421 aaatggtcaa ggacttggtg gacaatcaag gggctatctg tttgtccgga aaccacgagt
    27481 atatgttttt gacttggcta gatgacccag aagaaagtta tgaccattat cgtcgcaatg
    27541 gtggagatac aaccattaac tctatcctag gtcgtccctt ggatgcacca gttgatggag
    27601 tagaagatgc caaacgggtt gccgctgaag cggcagactt ggtcgaattc attcgtcaaa
    27661 tgccatttgt agtagagaca gacaagtata tctttgttca cgcaggtatt gatttgacct
    27721 tggatgattg gcatgaaaca acagattata aaaaagtctg gctcagaaaa ccgttccacg
    27781 aagccgaaaa tcatactgga aaaactattg tcttcggtca tacaccggtc tatggtttgt
    27841 tacagcaaga acgcggtaca tctgagcttt ggactacaga agatagcaag attggcatgg
    27901 acggaggagc tgtctatggt ggggtccttc acgggattgt ctttactgac cagggaatga
    27961 cagaacacta ctttatcgaa aatgacggct ttgttgctga agattagtac tcctagcagg
    28021 gtatggtctt gtcaaaatgt caaaaacaat ttataataaa tagataccct gaaaggaaga
    28081 gaatcatgaa cttagaagaa ttgaaaaaac gacaggagaa gatccgtaac ttctctatta
    28141 tcgcccatat tgaccacggg aaatcaactc tagcagaccg cattttggaa aaaacagaga
    28201 cggtttcaag tcgtgaaatg caggcccagc ttttggatag catggattta gaacgggaac
    28261 gtgggattac cattaagttg aatgccatcg agctgaatta cacggcaaaa gatggcgata
    28321 cttatatctt ccacttgatt gacactccgg ggcacgttga ctttacctat gaagtttcac
    28381 gttcgctcgc tgcctgtgag ggggctattt tggtggtcga tgctgcccaa ggaattgaag
    28441 ctcaaaccct tgctaacgtt tatctggcct tggacaatga tttggaaatc atgcctgtca
    28501 ttaataaaat tgacctgcct gctgcagatc cagagcgcgt gcgtacggag attgaggatg
    28561 tgattggttt ggatgccagt gaagcagttt tagcatctgc caaggctggc atcggtatcg
    28621 aagagatcct agagcaaatt gtagaaaaag taccagaacc aacgggtgat gtgacagcgc
    28681 ctcttaaagc cttgattttc gactctgttt acgatgctta ccgtggggtt attctccaag
    28741 ttcgtgttat ggatggggtg gttaaacctg gggataagat tcagctcatg agtaatggca
    28801 agacctttga tgtgacagaa gttggtattt ttactccgaa agcagttgat cgtgatttcc
    28861 ttgcgacggg tgatgttggt tatattgcgg cttctatcaa gacggttcag gacacccgtg
    28921 tcggtgatac cgttactttg gcaaccaatc ctgcggcaga gtccttacat ggttacaagc
    28981 agatgaatcc tatggtcttt gcgggtctct acccaatcga gtcaaacaag tacaatgacc
    29041 tgcgtgaagc gcttgaaaaa ttgcaactga atgatgctag tcttcagttt gaaccagaaa
    29101 catctcaggc ccttggattt ggtttccgtt gtggattcct tggacttctc catatggatg
    29161 ttatccaaga acgtttagaa cgtgagttca acatcgacct catcatgaca gctccatccg
    29221 ttatctataa ggttaatcaa accgacggtg agtcaatgga tgtgtctaac ccatctgagt
    29281 ttccagaccc aactaagatt gcgaccattg aagagcctta tgttaaagct caaataatgg
    29341 taccgcaaga gtttgttgga gcagtgatgg aattggctca gcgtaagcgt ggggattttg
    29401 tgactatgga ttatattgat gataaccgtg tcaatgttat ctatcaaatt ccgcttgctg
    29461 aaattgtctt tgacttcttt gataaactta agtcttcgac acgtggttat gcaagctttg
    29521 actacgaatt gtcagaatat cgcccatcta agctggtcaa aatggacatc cttctcaatg
    29581 gagacaaggt ggatgccctc agctttatcg ttcacaagga ctttgcctac gaacgtggga
    29641 aactcatcgt tgataagctc aagaaaatta tccctcgcca acaatttgag gttccaattc
    29701 aagcagctat tggacacaag attgtggctc gtactgatat caaggccctt cgtaagaacg
    29761 tacttgctaa atgttatggt ggtgacgttt ctcgtaagcg taaactgctt gaaaaacaaa
    29821 aagctggtaa gaaacgcatg aaagctatcg gatcagtaga agttccacaa gaagccttcc
    29881 ttagcgtctt gagcatggac gaagaataag ttattataat tgttttcttg ttcacaggaa
    29941 atttacataa gaatcaatag taaaacaggc ttaaattggc ctgttttttt agtttttata
    30001 ctcttcgaaa atctattcaa accacgtcag cgtcgccttg ccgtagatat gatcactgac
    30061 ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg ctagcttcct
    30121 agtttgctct ttgattttca ttgagtatta gaacagaaaa aatgctggta gtatttgttt
    30181 gtgtgtttat ttttatataa caaactacaa acgaaacaaa aatataaaaa aagagacaaa
    30241 aatcaacaga aaactattga caacggtttc atatagtgtt atacttatgg cataaagtta
    30301 atggaaagaa gggaaaactt tatgggatta gatcatttct ttgacaaaaa ccttgtgttt
    30361 tgcttagaag cggataatca agaacatctc tttgatcagg ttgcaacttt attggaagaa
    30421 cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa gtcatttcca
    30481 actggcttag atatggaatt tttgggtaag gatttgccga atgtggctat tcctcataca
    30541 gatattgttt ataatctagc tgaaaaagtt gtggtcgttc gattagagaa accggtgact
    30601 ttccacaata tgattgcgcc agataaggaa gtagaagtat ccttgctctt ctttatcatc
    30661 aataactcaa gttcaagtca aaccaacatt cttgctcagt tgatggactt ctttactgga
    30721 aatggtcatc ttgaagacct atcaaaaatt tctgaaccag aacccctcta tgcttatata
    30781 gctgaagcaa tcgcttaatc ttgtttatta aaaatattaa atcggaggaa atccatatga
    30841 ttaaaattct tgctgcctgc ggtgcaggtg ttaactcaag tcaccaaatt aaaagtgctc
    30901 ttgaagaaga actttcaaac cgtggttttg atgttcactg tgatgcggta atggtcaaag
    30961 acgttaatga agatcttatc aaaggttatg acatcttcac accaattgct gcgacagacc
    31021 ttggttttga cccaggtatt ccagttatcg aagctggact aatcttattc cgtatcccag
    31081 caatgagtgc tccagtattt gacaatattg aagcagctat caaagaacac gggttaagct
    31141 aattttaatt tgttaacatt catataacat aaaaaaggga ggaactgtta tgtatgcaat
    31201 ctttgaccta atcggaaagg ttttcaatcc catcttagat atgggtgggc ctgtcatcat
    31261 gttaatcatt ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga
    31321 aggtggtatc aaacttgcca tcgctcttac aggtatcggt gccatcatcg gtatgcttaa
    31381 cactgctttc tcagcgtcgc ttgcaaaatt cgttgaaaac actggtatcc aattgagtat
    31441 cactgacgtt ggttgggcac cacttgctac aatcacttgg ggttctgctt ggacactata
    31501 cttcttgctc atcatgttga ttgtcaacat agtgatgcta gctatgaaga aaacagatac
    31561 acttgacgtt gatatcttcg atatctgaca cttgtctatc acaggtcttt tgattaaatg
    31621 gtatgcagat aacaacggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat
    31681 cgtccttgtt ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga
    31741 ccttcttaac gctccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa
    31801 cccagttatc atggttttgg ataagatttt tgaaaaattc ttcccaggtc ttgataaata
    31861 cgactttgac gctgcaaaat tgaacaagaa aatcggtttc tgggattcta aattctttat
    31921 cggtttcatc cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggagt
    31981 tgaagatgca gataaatggc gtcttgttat cagaggatgg ttgtctcttg gtttgactgc
    32041 cggtgtatct ttggaactct tctcacttat cggttcatgg ttcattgcag ccgtagaacc
    32101 tctttcacaa ggtattacaa acgttgctac taaacgtctt caaggacgta aattcaacat
    32161 cggtcttgac tggcctttca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact
    32221 tgctccaatc atgttgattg aagctgttct tctttcaaaa gtcggaaatg gtatcttgcc
    32281 acttgcaggt atcatcgcta tgggtgttac tccagctctc ttagttgtaa ctcgtggtaa
    32341 attgctccgt atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac
    32401 acttattgca ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagcaggtgt
    32461 gagccaaact caattgatca ctcactcaac tcttgaagga ccaatcgaaa aacttcttgg
    32521 ttggacaatt ggtaacacta caactggtga tatcaaagca atccttggtg ctgtagtctt
    32581 ccttgtattc tatatcggta tctttgc
//
LOCUS       DAVDHZ010000024        30820 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000024 DAVDHZ010000000
VERSION     DAVDHZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30820
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.024"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            114..1244
                     /locus_tag="VUR46_001298"
     CDS             114..1244
                     /locus_tag="VUR46_001298"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET5456720.1"
                     /translation="MKKRSETIKYRRIVFKVGTSSLTNEDGSLSRSKVKAITQQLAML
                     HESGHELILVSSGAIAAGFGVLGFKKRPTKITDKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLSRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            1254..2516
                     /locus_tag="VUR46_001299"
     CDS             1254..2516
                     /locus_tag="VUR46_001299"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET5456721.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTVL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLDQ
                     MLVAERKEVGLEPIQFRLDSKASQFVSGQVAEAQDFDTEFLDYVLAVKVVSSLEEAVT
                     HIETHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            2520..3317
                     /gene="proC"
                     /locus_tag="VUR46_001300"
     CDS             2520..3317
                     /gene="proC"
                     /locus_tag="VUR46_001300"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET5456722.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDELLLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVGLGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEVHAFRGTVMDAVHQAYKRTQELGQ"
     gene            3537..4175
                     /locus_tag="VUR46_001301"
     CDS             3537..4175
                     /locus_tag="VUR46_001301"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET5456723.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLLILEEKGVEVLTSREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            4172..5062
                     /locus_tag="VUR46_001302"
     CDS             4172..5062
                     /locus_tag="VUR46_001302"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET5456724.1"
                     /translation="MKQEQLKAWQPAQFDRFVRILEQDQLNHAYFFSGFFGSLEMAQF
                     LAKSLFCTDKVDVLPCENCRNCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEQLILLLEQMGLVKKKATLLAQFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRVLEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            5102..5419
                     /gene="yabA"
                     /locus_tag="VUR46_001303"
     CDS             5102..5419
                     /gene="yabA"
                     /locus_tag="VUR46_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET5456725.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            5422..6291
                     /gene="rsmI"
                     /locus_tag="VUR46_001304"
     CDS             5422..6291
                     /gene="rsmI"
                     /locus_tag="VUR46_001304"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET5456726.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKVGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            6509..7564
                     /locus_tag="VUR46_001305"
     CDS             6509..7564
                     /locus_tag="VUR46_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET5456727.1"
                     /translation="MKKYNIVDLFSGAGGLSYGFEMAGFNVLLGIDNDEKALETFQKN
                     HQNSEILCGDIANISYEEDIKPIIGEQKIDIIVGGPPCQGMSLSGPRRFDDPRNKLYL
                     SYIRLVREIQPTAFVIENVIGIVSLFKGQIKDTIIEEFSKMGYKVQFKVLLASDYGVP
                     QNRKRVIFVGTRNDGFEYPEALGTIITTEMAISDLPTLENELGEIEMSYVSEPQNDYQ
                     KLMRKRSNVVLNHVAAKHSEKVISTIALVPDGGNYKNLPKELRETRKFNVAWTRFASW
                     KPAPTIDTGHRHHFHYKYNRVPTVRESARLQSFPDDFIFYGSKTQQFRQVGNAVPPLM
                     AQQIANNLLKYLKNNEE"
     gene            7567..8967
                     /locus_tag="VUR46_001306"
     CDS             7567..8967
                     /locus_tag="VUR46_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET5456728.1"
                     /translation="MYQVPEKYYFRLHHPRPRFKNDVENVLVYMATNISYLGILPKKE
                     FSQQLNDIIKQYAGNADKTEKTINNWRTEISSLFGMMIEKEGFVYSGNRAKELTEDQD
                     LIRFFKTFLYNFEYPGGHLKDNEIVKLCQIGVQFKPAQYLLELFTEASQAEEKTIYLT
                     DEEVAHCIFNDLRCTRDREPVLEIWNRIKENRASKVAYDTKGDVIRYAKDVLDYMVIA
                     SLLTVQGGRYKINSMEEQATNDFLQSDATFDGYAQFIGNASTTIEDVRNFRSAWFEYV
                     NRDLGDIDFRTNFNLYLPSDIDFTEEKTDIIGHLTEHIEYSEKISTAVVGSSGEAIVI
                     NHEKQKLREHGQEQLLHLVNFIPTQFGVGYDVQSFECDDSELRKYIEVKTTVSNASIT
                     FNSFHITPNEWRTAKSVRDRYYIYRLQISKHSKKLFIIKNLYELVKNEKMLLIERKDG
                     YDARFSSSVGFEENLI"
     gene            8964..10004
                     /gene="dcm"
                     /locus_tag="VUR46_001307"
     CDS             8964..10004
                     /gene="dcm"
                     /locus_tag="VUR46_001307"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET5456729.1"
                     /translation="MKKLKIASLFSGGGGTDIGFAGGFDFLGKHYADNQIEIVYANDI
                     EDSANKMFEKNFGVTPDNRNIREIKSDEIPSFDILTGGFPCQSFSVSAQNPKRLGIKD
                     EKGTLFFEMVRVLKAHQPKAFFAENVKGILSANNKEAFPLIIEEFEKAGYNVSYKLCV
                     ATKYGVPQKRERVFIVGIRKDLNFTFEFPEEPIQNVEDYTPLKVILQQDIDEKYYFSE
                     RAVQGMLNSKSGKKMNKGRAQDIEQPSNTVSSHLAKVSLNSTDPVLLENGRYRRYTPR
                     EVARIQSFPENYELLGSEGAQYRMLGNAIPPVMMWYIAEKLVSDLRNSDVIAKQQKLE
                     ESFGQLDLFEAS"
     gene            10029..10823
                     /locus_tag="VUR46_001308"
     CDS             10029..10823
                     /locus_tag="VUR46_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HET5456730.1"
                     /translation="MELNFQDKSFIKVFFNSDGYVLNFSNSTFANFTFNSVGVNIQEK
                     YGGSKGKALQAFVDNEPDELVLKLALDLLRYYEDLPDSYYEKTEERNSQALKLKERLS
                     KYEVSQIAYLNNAAKSLSDYFDSDYIDKQMGIMNEMISRSPADAIGKAKELLESCFKH
                     ILDHEKIEYSNSNDIATLQKKVFKFLNLDSNENISAKNNQDVKVVLSGLNQIIKGINN
                     LRNDKGDGHGKGANFIELPPRYASVVVGSALTVVSFVWETYQDKQK"
     gene            10841..11404
                     /locus_tag="VUR46_001309"
     CDS             10841..11404
                     /locus_tag="VUR46_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HET5456731.1"
                     /translation="MSKNQEKLHFQLKKFIVNVGWTHKIHAVRIDELESYIRWFRIAT
                     IIISGVVSSGLVGILWFDEYWIKLVTAFLSLVTTIIFSITKEFNFEERLALERKSVDE
                     LWNLRVLAEILLSEVVYNGKPSSEIQEFFEELKFRRDATYSQLSNASPKNVSKASKLI
                     KSRKDNDYEEDYRYFIPKELMEIKEEE"
     gene            11404..12726
                     /locus_tag="VUR46_001310"
     CDS             11404..12726
                     /locus_tag="VUR46_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET5456732.1"
                     /translation="MSLSNDFKEFCEDELPMTDEEWEKWENRLKEITKRLNRKFYSLD
                     ELDDQETDNGLIVGSVGRTTAVRNVSDFDYIFSLPSEVYRRFDSYEGNGQSALLQEIK
                     NELLKRYPNTKIKGDGQVVVIDFSDGGKIELVPAFEKSDGNFKYPDSRNGGSWKTTKP
                     KFEIEKCKSLNSNFNSHFSNLTRLIRQWKNHMGFSFKGLLIDTLISDLIDDKGISEIY
                     YSDYNILLKDIFEYFSNQDKNREYWYALGSNQKIYNNDGAKFVNKAKQALKKIEDASE
                     EKLTEVYRQLFGRKFAQSTSTTNRASNEEFIDELFNVNIEYNIVLECEITQDGFRKAL
                     LSDFLKSRFKIKNRKSLDFEIIKSDIPDNLLSDVKYYWKVRNIGAEAIRRNCERGAIF
                     SGKIKHHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            13070..14404
                     /gene="trmFO"
                     /locus_tag="VUR46_001311"
     CDS             13070..14404
                     /gene="trmFO"
                     /locus_tag="VUR46_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET5456733.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESATSGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            14488..15213
                     /locus_tag="VUR46_001312"
     CDS             14488..15213
                     /locus_tag="VUR46_001312"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET5456734.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRSAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNI"
     gene            15234..15791
                     /gene="frr"
                     /locus_tag="VUR46_001313"
     CDS             15234..15791
                     /gene="frr"
                     /locus_tag="VUR46_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET5456735.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLII
                     PVLTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            15851..16705
                     /gene="cvfB"
                     /locus_tag="VUR46_001314"
     CDS             15851..16705
                     /gene="cvfB"
                     /locus_tag="VUR46_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET5456736.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            16714..16929
                     /locus_tag="VUR46_001315"
     CDS             16714..16929
                     /locus_tag="VUR46_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET5456737.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            17015..17983
                     /locus_tag="VUR46_001316"
     CDS             17015..17983
                     /locus_tag="VUR46_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET5456738.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVILAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(17961..18140)
                     /locus_tag="VUR46_001317"
     CDS             complement(17961..18140)
                     /locus_tag="VUR46_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456739.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQQYI
                     LLQANFLKISRVQLQ"
     gene            18176..18676
                     /locus_tag="VUR46_001318"
     CDS             18176..18676
                     /locus_tag="VUR46_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456740.1"
                     /translation="MIDQLSKYYSCRILTEKNIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFIGFWNGSDLVAVMDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKACLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            18679..18939
                     /locus_tag="VUR46_001319"
                     /pseudo
     CDS             18679..18939
                     /locus_tag="VUR46_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(19306..20417)
                     /gene="ald"
                     /locus_tag="VUR46_001320"
                     /pseudo
     CDS             complement(19306..20417)
                     /gene="ald"
                     /locus_tag="VUR46_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            20594..21163
                     /locus_tag="VUR46_001321"
     CDS             20594..21163
                     /locus_tag="VUR46_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456741.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYTSDKGNTRY
                     TFPTNQILEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            21230..21880
                     /locus_tag="VUR46_001322"
     CDS             21230..21880
                     /locus_tag="VUR46_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET5456742.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            21864..24104
                     /locus_tag="VUR46_001323"
     CDS             21864..24104
                     /locus_tag="VUR46_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET5456743.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFALSFLYPVIQLNFIFEWLEGMIRLVSQVASRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKRLAVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESEKKIEKWQEKATTSNAQRTLIPYLKSRGVSKIDQLILTNTDKEHIGDL
                     LEVTKAFHVGEILVSKGSLKQKEFVVELQATQNKVRSVSVGENLLIFGSQLEVLSPRK
                     IGDGGHDDTLVLYGKLLDKQFLFTGNLEEKGERDLLRQYPDLEVDVLKASQHGSKTSS
                     SSAFLEKLKPEITLISVGKSNRTKLPHQETLTRLETINSKVYRTDQQGAIRFKGWKSW
                     KIESVR"
     gene            24504..25097
                     /locus_tag="VUR46_001324"
     CDS             24504..25097
                     /locus_tag="VUR46_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456744.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFEKGRIYGILAINGSGKTTLFR
                     TISNLIPISSGNIAAPPSLFYYESVEWLDGSLSGIDYLRLIKNIWKSDLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEVPL"
     gene            25094..26278
                     /locus_tag="VUR46_001325"
     CDS             25094..26278
                     /locus_tag="VUR46_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456745.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLLLFASVLGVTFYLNSQTANSVS
                     LESRLESRIVDNGRAINENEAKLSQMSDTSSEEYQFAKNNLDLQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            26497..26826
                     /locus_tag="VUR46_001326"
                     /pseudo
     CDS             26497..26826
                     /locus_tag="VUR46_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282476.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27093..27371
                     /locus_tag="VUR46_001327"
     CDS             27093..27371
                     /locus_tag="VUR46_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456746.1"
                     /translation="MWLETIVCFDCDYEEKWEEDNIFKPIHCPECRDVLDVVERDWLG
                     ETILRSTVQCERCNFLFDHLDFQLGLSECPSCFSKELKLVRQKKEIVE"
     gene            27368..27532
                     /locus_tag="VUR46_001328"
     CDS             27368..27532
                     /locus_tag="VUR46_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456747.1"
                     /translation="MTKEMFVQFSKKAAVNEVMRKTGMSKKRAVKAVEELEREGVLFS
                     MGNGTVMMGV"
     gene            27537..28631
                     /locus_tag="VUR46_001329"
     CDS             27537..28631
                     /locus_tag="VUR46_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET5456748.1"
                     /translation="MADITVNQVATQTFYQIPQIFMVNVKKKFSAEGKPTGKIKMTSL
                     YAKKLSNDGKIAYGVLYDRCMLSIYSYRNGELTYVDENGSVFLVYTVEDLMEILDRSK
                     PTVLKIKKELKELGLLREVKQGKNRPNRLYLQNVNAELQEYEHYDAEVVEKGRDKGTV
                     VYHHVKTLDYKGCVLFEIERPGSEEESSILKDENSVLEKPIKSINSGSQKSLPPEVKN
                     FNPIKTEKSHTENNSTRHSSRKPASNSKELDQTAGTCDTPSQKTSGKKFIKPQVYSLL
                     QEIADSYRDHLPWYQHYNMTHRQKMIVGQYIQTGWITSSEVLHCIERIPECDSPFAYL
                     IQSIENLIGERKSEAKMQAHREAEYRYLSN"
     gene            28943..29257
                     /locus_tag="VUR46_001330"
     CDS             28943..29257
                     /locus_tag="VUR46_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456749.1"
                     /translation="MNQSKLVTEVTLADLRRLGNQGNATARLDNGDEIKLTSRYGLVP
                     KKGYLAGKLETVWMIVEYSKIYKEIRTIKRGDVLVVRRIKQGNTNRLLLTGKGYHRPT
                     KH"
     gene            29449..>30820
                     /locus_tag="VUR46_001331"
     CDS             29449..>30820
                     /locus_tag="VUR46_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HET5456750.1"
                     /translation="MKLRTTILATTASVTLLGLGNSQPVYANSTTSSQVESLKSEFIK
                     AKREYEQAKSIYDNALSSSPSNTIILSDKYIKALKTAFSDFNISQTERDSAKSILQSE
                     SLRLKNQNSFHKDVADEGERLDVNNLPLAVRQELSFFAQDLINQVRSQVGTPRVSVSI
                     SALDFADKVAKAYVQDNWGWHKMSVSGTLGHDATGINHVAREYGLPTTNSEEEKKGEQ
                     NYENLASRLPGFKTANKAQLKEAIYIGMIEFMFNDTEWMHAQSIAGLNWGNVNSKDYF
                     GLSFSSRSSVSSAHFITVSQEDIKRASKSSFSTAAVSDPTSVNRRQAIKKLEEDYKAK
                     EKIYQDFQKQADSKGSQGQSNQGSATVTEPSKPSAGSAEPTKSIENTSDLRDQWKQEG
                     SYWYYFDRAGKALVNSWKGNYYLKSNGVMARNEWVYDTNYKAWYYFKSDGSYAQNSWQ
                     GSYYLKS"
BASE COUNT         9658 a         5255 c         6941 g         8966 t
ORIGIN      
        1 aaaaataggc tccataatat ccatagggga tttacccact acaaatatta tagagcctct
       61 ttttcctatc aactcttttc tatttcctgt tattcatgtt ataatggata aatatgaaga
      121 aacggagtga gactataaaa tacagacgga ttgtctttaa ggttgggact tcttctctga
      181 caaatgagga tggaagttta tcacgtagta aggtaaaggc tatcacccag cagttggcta
      241 tgttgcacga gtctggtcat gaattgattt tggtgtcgtc aggtgccatt gcagctggtt
      301 ttggggtctt aggatttaaa aagcgtccga ctaagattac tgataaacag gcttcagcag
      361 cggtaggaca agggcttttg ttggaagaat acacgactaa tcttctcttg cgccaaatcg
      421 tttctgcaca aatcttgctg acccaggatg attttgtgga taagcgccgt tataaaaatg
      481 cccatcaggc tttgtcagtt ctacttagcc gtggggcaat tcctattatc aacgagaacg
      541 atagtgtcgt tattgatgag ctcaaggttg gggacaatga tactctgagt gcccaggtag
      601 cggccatggt ccaagctgac cttttggtcc tcttgacaga tgtagacggt ctctatactg
      661 gaaatcctaa ttcagaccca agagccaaac gcttggagcg aatcgagacc atcaatcgtg
      721 agattattga tatggctggt ggagctggtt cgtcaaacgg aactgggggc atgctaacaa
      781 aaattaaggc tgcaactatc gcgacggaat caggagttcc tgtttatatc tgctcatcct
      841 tgaaatcaga ttccatgatt gaggcggcag aggagaccga ggatggttct tactttgttg
      901 ctcaagagaa ggggcttcgt acccagaaac aatggcttgc cttctatgct cagagtcaag
      961 gttctatttg ggttgataaa ggggctgcgg aagctctctc tcaacatgga aagagtcttc
     1021 tcttatctgg tatcgttgaa gcagaaggag ccttttctta cggtgatatc gtgacagtat
     1081 ttgacaagga aagtggaaaa tcacttggaa aaggacgcgt gcaatttgga gcatctgctt
     1141 tggaggatat gttgcgttct caaaaagcca agggtgtctt gatttaccgt gacgactgga
     1201 tttccattac tcctgaaatc caactacttt ttacagaatt ttagaggtaa actatggtga
     1261 gtagacaaga acaatttgaa caggtacagg ctgttaaaaa atcgattaac acagctagtg
     1321 aagaagtgaa aaaccaagcc ttgctagcca tggctgatca cttagtggct gctactgagg
     1381 aaattttagc ggctaatgcc ctcgatatgg cagcggctaa ggggaaaatc tcagatgtga
     1441 tgttggatcg tctttatttg gatgcagatc gtatagaagc gatggcaaga ggaattcgtg
     1501 aagtggttgc cttaccagat ccaatcggtg aagttttaga aacaagtcag cttgaaaatg
     1561 gtttggttat cacaaaaaaa cgtgtagcta tgggtgtcat cggtattatc tatgaaagcc
     1621 gtccaaatgt gacgtctgat gcggctgctt tgactcttaa gagtggaaat gcggttgttc
     1681 ttcgtagtgg taaggatgcc tatcaaacaa cccatgccat tgtcacagtc ttgaagaagg
     1741 gcttggagac gactactatt catccaaatg tgattcaact ggtggaagat actagccgtg
     1801 aaagtagcta tgccatgatg aaggccaagg gttatctaga tcttctcatt cctcgtggag
     1861 gagctggctt gatcaatgca gtggttgaga atgcgattgt acctgttatc gagacaggga
     1921 ctgggattgt ccatgtctat gtggataagg atgcagacga agacaaggcg ctgtctatca
     1981 tcaacaatgc taaaaccagt cgtccttctg tttgtaatgc catggaggtt ctccttgttc
     2041 atgaagataa ggcagcaagc ttccttcctc gcttggatca aatgctggtt gcagagcgta
     2101 aggaagttgg actggaacca attcaattcc gcttggatag taaagcaagt cagtttgttt
     2161 caggtcaagt agctgaagca caagactttg acaccgagtt tttagactat gtcctagcgg
     2221 ttaaggttgt gagcagttta gaagaagcgg ttacccatat tgaaacccac agtacccatc
     2281 attcggatgc cattgtaacg gaaaatgctg aagctgcagc ttactttaca gatcaagtgg
     2341 actctgcagc ggtgtatgtt aatgcctcaa ctcgtttcac agatggagga caatttggtc
     2401 ttggttgtga aatggggatt tctactcaga aattgcacgc gcgtggtcca atgggcttga
     2461 aagagttgac cagctacaag tatgtggttg ctggtgatgg gcagataagg gagtaagaga
     2521 tgaagattgg atttatcggt ttggggaata tgggtgctag cttggcaaaa tctgtcttgc
     2581 agactaggac gtcagatgag cttctccttg ccaatcgtag tcaagccaag gtagatgctt
     2641 tcattgcaga ctttggtggt caggcttcca gcaatgaaga aatgtttgca gaagcagatg
     2701 tgatttttct aggagttaag cctgctcagt tttctgaact gctttctcaa taccagacca
     2761 tccttgaaaa aagagaaagt cttcttttga tttcgatggc agctggattg accttagaaa
     2821 aactagcaag tcttatccca agtcaacacc gaattattcg tatgatgccc aatacccctg
     2881 cttctatcgg gcaaggagtg attagttatg ccttgtctcc taattgccgg gctgaggaca
     2941 gtgagctctt ttgtcagctt ttagccaagg ctggtctctt ggttggatta ggagaaagct
     3001 taatcaatgc agcgacaggt cttgcaggtt gtggaccagc ctttgtctat ctctttattg
     3061 aggccttggc agatgcgggt gttcagacgg gattaccacg agaaacagcc ttgaaaatgg
     3121 cagcccaaac tgtggtagga gctgggcaat tggtcctaga aagccagcaa catcctggag
     3181 ttttgaaaga tcaagtttgt agtccaggcg gttcgactat tgccggcgta gcaagcctag
     3241 aagtgcatgc ttttcgagga acggtcatgg atgcagttca tcaagcatat aaacgaacac
     3301 aagaactagg tcaataagag gtagttttat ctgcctcttt tatggtggtt gatactcttc
     3361 gaaaatcaaa ttcaaactgc gtcagcttca ccttgccgta ctcaagtaca gcctgcggct
     3421 agcttcctag tttgctcttt aattttcatt gagtatgaaa tgagaagaca aaaagattgt
     3481 cacaaacccc tatttttttg atagaataga agtagtaaaa aagaaatgag ttagacatgt
     3541 caaaaggatt tttagtctct cttgagggac cagagggagc aggcaagacc agtgttttag
     3601 aggctctact actaatttta gaggaaaaag gagtagaggt gctgacgagc cgtgagccag
     3661 gcggtgtctt gattggggag aagattcggg aagtaatttt ggatccaagt catactcaga
     3721 tggatgcgaa gacagagttg cttctctata ttgccagtcg cagacagcac ttggtggaaa
     3781 aagttcttcc agcccttgaa gctggcaagc tggtcattat ggatcgtttt atcgatagtt
     3841 ctgttgccta tcagggattt ggtcgtggct tagatattga agccattgac tggctcaatc
     3901 agtttgcgac agatggcctc aaacccgatt tgacactcta ttttgacatc gaggtggaag
     3961 aaggactggc tcgtattgct gctaatagtg accgcgaggt taatcgtttg gatttggaag
     4021 ggttggactt gcataaaaaa gttcgtcaag gctacctttc tcttctggat aaagagggaa
     4081 atcgcattgt caagattgat gctagtctcc ctttggagca agttgtggaa actaccaagg
     4141 ctgtcttgtt tgacggaatg ggcttggcca aatgaaacaa gaacaattaa aggcttggca
     4201 accagcccag tttgaccgat ttgtccgtat cttagaacaa gaccagctca atcacgccta
     4261 tttcttttca ggtttctttg gaagcctgga aatggcgcag tttttggcca agagtctatt
     4321 ttgtacggat aaggtagatg ttttaccatg tgaaaactgc cgaaattgta agctgattga
     4381 acagggagag tttccagatg taaccttgat taagccagtc aatcaggtca tcaagacaga
     4441 acgcattcgg gaattggtgg gacagttttc tcaagcaggg attgaaagcc agcaacaggt
     4501 ctttatcatc gagcaagcgg ataaaatgca tcccaacgca gccaattctc tgcttaaggt
     4561 catcgaagaa ccccagagtg aagtttatat tttcttcttg actagcgatg aggaaaagat
     4621 gttaccgaca atccgaagtc ggacccagat tttccacttt aaaaagcaag aagaacaact
     4681 catcttgctc ttagaacaaa tgggacttgt taagaaaaaa gcgactcttt tagctcagtt
     4741 tagtcaatcg cgagctgaag cagaaaagtt ggctaatcag gcaagttttt ggaccttggt
     4801 cgatgaaagt gaacgcctgc tgacttggtt agtagctaag aaaaaagaaa gttatctaca
     4861 ggttgccaaa ttagcgaact tggcagatga taaggaaaaa caagatcagg ttttacgggt
     4921 tcttgaagtt ctctgtgggc aggacctctt gcaggtaaga gtaagggtga ttctacaaga
     4981 tttgctagaa gctagaaaaa tgtggcaagc taatgtcagc tttcaaaatg ccatggaata
     5041 tctggtcttg aaagaaatat aaactcaaaa atgaacgata aagaaaggaa aggcctggct
     5101 tatggacaaa aaagaattat ttgacgcgct ggatgatttt tcccaacagt tattggtaac
     5161 cttggccgat gtggaagcta tcaagaaaaa tctcaagagc ctagtagagg aaaatacagc
     5221 tcttcgtttg gaaaattcta agttgcgcga acgtttgggt gaggtggaag cagacgctcc
     5281 cgtcaaggcc aagcatgttc gcgaaagtgt tcgtcgcatt taccgtgatg gatttcacgt
     5341 atgtaatgat ttttatggac aacgtcgaga acaggacgag gaatgtatgt tctgtgacga
     5401 gttgttatac agggagtaag catgcagatt caaaaaagtt ttaaggggca gtctccctat
     5461 ggcaagctgt atctagtggc aacgccgatt ggcaatctag atgatatgac ctttcgcgct
     5521 atccagacct tgaaagaagt ggactggatt gctgctgagg atacgcgcaa tacaggtctt
     5581 ttgctcaagc attttgacat ttccaccaag cagatcagtt ttcatgagca caatgccaag
     5641 gaaaaaattc ctgatttgat tggtttcttg aaagtagggc aaagtattgc tcaggtctct
     5701 gatgccggtt tgcctagcat ttcagaccct ggtcatgatt tggttaaggc agctattgag
     5761 gaagaaattg cagttgtgac tgttccaggt gcctctgcag gaatttctgc cttgattgcc
     5821 agtggtttag ctccacagcc acatatcttt tacggttttt taccgagaaa atcaggtcag
     5881 cagaagcaat tttttgactc gaaaaaagat tatcctgaaa cacagatttt ctatgaatca
     5941 cctcatcgtg tagcagacac gttggaaaat atgttagaag tctacggtga ccgctccgtt
     6001 gtcttggtca gggaattgac caaaatctat gaagaatacc aaagaggtac aatttctgaa
     6061 ttgctggaaa gcatctctga aacgtctctc aagggtgaat gtcttctgat tgttgaaggt
     6121 gccagtcagg atgtggaaga aaaagacgag gaagacttgt tcttagaaat ccaagctcgt
     6181 atccagcaag gtatgaagaa aaatcaagct attaaggaag tagctaagat ttaccagtgg
     6241 aataagagtc aactctacgc agcctaccac gactgggaag aaaaacaata aagggagaca
     6301 ggatgtaata attctgtctg tttctgttta acttaattag tgatgataat attcggagtc
     6361 taaataatag aattgattga gtagtgaata aataaaaaca atgttcattc agtttacgtt
     6421 gaatatatat aatgtactct attagaatta tttttaagta cgcagtatgg tataattata
     6481 tatgagaaaa tagtgtggag tttatcagtt gaaaaaatat aacattgtag atttattttc
     6541 aggagcaggt ggtctatctt atggattcga gatggctgga tttaatgttc tattaggaat
     6601 tgataatgac gaaaaagcct tagaaacctt tcaaaaaaat catcagaatt cagaaatatt
     6661 atgtggagat attgcgaata tatcttatga ggaagatata aaaccaataa ttggagaaca
     6721 aaaaattgac ataattgtag gtggtccccc ttgtcagggg atgtcgcttt ctggacctag
     6781 aagatttgat gatccaagga acaaacttta tttgtcttat attcgattgg ttcgagaaat
     6841 acagccaact gcttttgtca ttgaaaatgt gattgggatt gttagtttgt ttaaagggca
     6901 aataaaagat actatcatag aagaattttc gaaaatgggt tataaggttc agtttaaagt
     6961 gttgctggcc tctgactatg gagttcctca aaatagaaaa cgtgttattt ttgtggggac
     7021 gaggaatgat ggatttgaat atcctgaagc attgggaaca atcattacaa cagagatggc
     7081 aatttctgat ttaccaacat tagaaaatga acttggcgag atagaaatgt cttatgtttc
     7141 agaaccacaa aatgactatc aaaaactaat gcgaaaacgt tcaaacgtag ttttgaacca
     7201 cgttgcagcc aagcattcag aaaaagtgat aagtacaatt gcccttgtcc ctgacggtgg
     7261 aaattataaa aatctcccga aggaattacg agaaacaaga aaatttaatg tcgcttggac
     7321 acgatttgct agttggaagc cagctcctac gattgatacg gggcatagac atcatttcca
     7381 ctataagtat aatcgtgtgc caacagtgag ggaatctgct cgtctacaat cttttccaga
     7441 tgattttatc ttttacggaa gtaaaacaca gcaatttaga caagttggta atgctgttcc
     7501 tcctttaatg gctcagcaga ttgcaaacaa tttactgaaa tatttaaaaa ataacgaaga
     7561 gtaactatgt atcaagttcc agagaaatat tattttagac tacatcaccc aagacctcgt
     7621 tttaaaaatg atgtcgaaaa tgtacttgtt tatatggcaa cgaatatttc ttatttggga
     7681 atattgccta aaaaggaatt tagtcagcaa ctaaatgaca ttatcaaaca atatgcagga
     7741 aatgcagata aaacagagaa aacaatcaat aactggcgaa cagagatttc ttctttgttt
     7801 ggaatgatga ttgagaaaga aggctttgtc tattcaggaa atagggctaa ggaattgact
     7861 gaagaccaag accttattcg cttttttaaa acctttttgt ataattttga atatcctggt
     7921 gggcatctaa aagataacga gattgttaaa ctttgtcaaa tcggagttca atttaagcca
     7981 gctcagtatc tactggaact atttacagaa gcctcacaag ctgaagaaaa aactatttac
     8041 ctcaccgatg aagaagtcgc ccattgtatc tttaatgatt tgagatgtac tcgtgataga
     8101 gagcctgttt tggaaatatg gaatcgtatc aaagagaata gagcgtctaa agtagcttac
     8161 gatactaaag gagatgttat tcgatatgcc aaagatgttt tagattacat ggttatagcg
     8221 agtttactaa ctgttcaagg tggtaggtat aaaataaatt ctatggaaga gcaagcaaca
     8281 aatgactttt tgcaatcaga tgctaccttt gatggctatg ctcaatttat tggaaatgct
     8341 tctacaacaa ttgaagatgt tcgaaatttt agaagtgctt ggttcgaata tgtcaatcgt
     8401 gatttaggag atattgattt taggacaaac tttaatctct accttccaag tgatattgat
     8461 tttactgaag agaaaacaga tattatcgga catctaactg aacacatcga atacagcgag
     8521 aaaatatcta ccgctgttgt agggagttcg ggagaagcta ttgttatcaa tcatgaaaaa
     8581 caaaaattac gagaacatgg gcaagaacag ttgctccatc tggtgaattt tattccaaca
     8641 cagtttggtg tcggctacga tgttcaatct tttgagtgtg atgattctga gctgagaaag
     8701 tatattgaag tcaaaacaac tgtcagcaat gcttctatta cttttaattc gtttcatatc
     8761 acaccaaacg aatggcgaac tgctaaatct gtgcgtgata gatactatat ttatcgtttg
     8821 cagatttcta aacatagcaa aaaattgttt attatcaaga atttgtatga gttagtcaaa
     8881 aatgagaaga tgcttctgat tgagagaaaa gatggatatg atgcccgttt ttcatcgtca
     8941 gttggctttg aggagaattt aatttgaaga aactaaaaat tgcctctctt tttagtggag
     9001 ggggtggaac ggatattggt tttgctggtg gatttgattt tttaggtaaa cattatgccg
     9061 acaatcaaat tgagattgtc tatgcaaatg atattgaaga cagtgccaat aaaatgtttg
     9121 aaaagaattt tggtgttact ccagacaatc gaaatatccg agaaataaaa tcagatgaaa
     9181 tcccatcttt cgatatttta acgggaggtt ttccttgtca atcattttct gttagtgctc
     9241 aaaatccgaa acgcttagga ataaaagacg aaaaagggac attgtttttt gagatggtgc
     9301 gagtgttaaa agctcatcaa ccaaaagcat tttttgccga aaatgttaag ggaattttgt
     9361 ctgcaaacaa taaagaagcc tttcctctaa ttattgaaga gttcgaaaaa gctggttata
     9421 atgtttctta taaactttgc gtagccacca aatacggcgt tccgcaaaag agagagcgtg
     9481 tgtttattgt tggtattcga aaggatttga attttacttt tgaatttcct gaagagccta
     9541 ttcaaaatgt agaagattat acaccactaa aagtaattct tcagcaagat attgatgaaa
     9601 agtattattt tagtgagagg gctgtgcaag gaatgctaaa tagtaaatct ggcaaaaaaa
     9661 tgaataaagg acgagcacaa gacattgaac agccgagtaa tacggttagt tctcacttag
     9721 caaaagtatc cttaaatagc actgaccctg ttttgttaga aaatggacgt taccgtcgct
     9781 atactccaag agaggttgca cgtattcagt cgtttccaga aaactatgaa ttgcttggtt
     9841 cagaaggtgc tcaatataga atgctgggga atgctattcc accagtaatg atgtggtata
     9901 ttgctgaaaa gttagtgtca gatttacgaa atagtgatgt aattgcaaag caacagaaac
     9961 tcgaagaaag ttttggtcaa ctggatttgt ttgaagcgag ttgatgtttt aaatctaggg
    10021 aacttgatat ggaattaaat tttcaagata agagttttat aaaagtattt tttaatagtg
    10081 acggttatgt attaaatttt tctaactcta cttttgctaa ttttactttt aattcagtag
    10141 gagtaaatat tcaagagaaa tatggaggtt caaaagggaa agctttacag gcttttgtag
    10201 ataacgaacc agatgaactg gttttaaaat tggctttaga tttacttaga tattatgaag
    10261 accttcctga ctcatattac gagaaaactg aagagaggaa ctctcaggca ttgaaattga
    10321 aagagagact ttcgaaatat gaagtctcac aaatagccta cttaaataat gctgctaaat
    10381 ctttatctga ctattttgat agcgactata tagataagca aatggggatt atgaatgaaa
    10441 tgatttctcg ctctccagcg gacgctattg gaaaagctaa ggaattgttg gaatcgtgtt
    10501 ttaaacatat tttagaccat gaaaaaattg agtattctaa ttctaatgat attgcaactt
    10561 tgcaaaagaa agtctttaaa tttttaaact tggattctaa tgaaaatatt tcagcaaaaa
    10621 ataatcaaga tgtgaaggtg gttctaagtg gtttgaatca aattatcaag ggtattaaca
    10681 atcttagaaa tgataaaggc gatggtcatg gtaagggagc taactttata gaattgccac
    10741 caaggtatgc ttcagttgtt gtaggttctg cattaacggt agtgtcattt gtttgggaaa
    10801 cataccaaga taagcaaaaa tagtaaagga gggagattta atgtcgaaaa atcaagaaaa
    10861 attacacttt caacttaaaa aatttatagt aaatgtaggt tggactcaca aaattcatgc
    10921 ggttagaatt gacgagttag aaagctatat tcgatggttt agaatagcaa caataatcat
    10981 ttctggagtt gtctcttctg gcttagttgg aatactttgg tttgatgaat attggataaa
    11041 gcttgttaca gcatttttat cattagtcac gacaataatt tttagcatca caaaggagtt
    11101 taactttgag gaacgactag ctttggagag gaaatctgtt gatgagcttt ggaatcttag
    11161 agtgttagct gaaattcttt tatctgaggt ggtttacaat ggaaaaccat ccagtgaaat
    11221 ccaagaattt ttcgaagaat taaaatttcg aagagatgct acttatagtc aactttctaa
    11281 tgcttctccc aaaaatgtat ccaaggcttc aaaactaata aaatcgagaa aagataatga
    11341 ttatgaggag gattatagat actttattcc aaaagaattg atggaaatta aggaggaaga
    11401 gtaatgtctt tatctaatga ttttaaagaa ttttgcgaag acgaactccc catgacggat
    11461 gaggaatggg aaaaatggga gaatagatta aaagagatta cgaaacgact taatcgaaaa
    11521 ttttattcct tagatgagct tgacgatcaa gaaactgaca acggtttgat tgttggtagt
    11581 gtggggagaa cgacggctgt tcgaaatgtt agtgattttg attatatttt ttctctacca
    11641 tcagaagtgt atagacgatt tgattcttat gagggcaatg gtcaatcagc actcctacag
    11701 gaaataaaaa acgaattact aaaaagatac ccaaatacaa aaataaaagg agacggacag
    11761 gtcgttgtta ttgatttttc ggatggtgga aaaattgagt tagttccagc tttcgaaaaa
    11821 tctgatggta attttaaata tcctgattct cgtaacggag gctcttggaa aactactaaa
    11881 ccaaagtttg aaattgaaaa atgcaaatct ttaaattcca attttaatag tcatttttct
    11941 aacttaacaa ggctcatacg acaatggaaa aatcatatgg gcttttcatt taaggggttg
    12001 ttgatagata ctttgatatc tgatttaatt gatgataaag gtatttctga aatatattat
    12061 tctgattata atattctctt gaaagatatt tttgaatact tttcaaatca agataaaaat
    12121 agagagtatt ggtatgcttt aggtagtaat caaaagattt ataataatga tggagcaaaa
    12181 tttgtcaata aagctaagca ggctctaaag aaaatagaag acgcttcaga agagaaactt
    12241 actgaagttt atagacagct atttggtaga aaattcgctc aatctacttc tacaacaaat
    12301 cgagcttcga atgaagaatt tattgatgaa ttgtttaatg ttaatatcga atataatatt
    12361 gttttggagt gtgaaattac acaagatggt tttcgaaaag cacttctttc agacttttta
    12421 aaaagtagat ttaagattaa aaatagaaaa tctcttgatt ttgaaattat aaaatcagat
    12481 attccagata atcttttgtc tgatgttaaa tattattgga aagtgagaaa tattggagct
    12541 gaggcgatta gaagaaattg tgagcgtggt gctatttttt caggtaaaat aaaacatcac
    12601 gaagattctc agtttaaagg agaccactat gttgaatgtt atgctgtttt agataatacg
    12661 gttatagcaa gagatagaat aacagtccct atcgatccgt tatgtggaaa agattttata
    12721 gagtagcata taattgattc ttaactggaa tactctctat ctctttacat caagaaaatg
    12781 actaaacagg gaagtttgcc ttcttccctt tttttgttat actagtagaa gaaaaaaata
    12841 gaaagatttg tgggagtgaa aaagtccggg ggactttttc agcttgagcc aagaaattcg
    12901 agagcgagga aagtctgggg gactttttca gcctgagcca agaaattcga gagcgaagta
    12961 agtccaatgg actttttcag cctgagccaa gaaactcgaa agctcgtaag tctgattggc
    13021 tttttcaatg tgaatcttaa cttcacactc ccaaagaggt attagtgtcg tgtctcaatc
    13081 ttatatcaat gttatcggtg ctggtttggc aggttctgaa gcagcttacc aaatcgcaga
    13141 gcgtggtatt ccagttaaac tttatgaaat gcgtggtgtc aagtcgactc ctcagcacaa
    13201 aacagacaat tttgctgagt tggtttgttc caattctttg cgtggggatg ctttgacaaa
    13261 tgcagttggt cttctcaagg aagaaatgcg tcgcttgggt tctgttatct tggaatctgc
    13321 tgaggctaca cgtgttcctg ccggtggagc ccttgcggtg gatcgtgatg gtttctctca
    13381 aatggtgacc gaaaaagtgg tcaaccaccc cttgattgaa gtggtgcgtg atgaaattac
    13441 agaattgcca acagatgtta ttacagttgt ggcgactggt cccttgacta gcgatgccct
    13501 ggctgaaaag attcatgccc ttaataatgg cgatggcttc tatttctacg atgcagcagc
    13561 gcctattatc gatgtcaaca ctatcgatat gagtaaggtc tatctcaaat ctcgttatga
    13621 taagggagaa gcagcctatc tcaatgctcc aatgaccaag caagagttta tggatttcca
    13681 tgaagccttg gtcaatgcgg aagaagcacc gctcaattct tttgaaaaag aaaagtactt
    13741 tgaaggatgt atgccaatcg aagttatggc caaacgtggc attaaaacta tgctttatgg
    13801 ccctatgaag ccagtcggtc ttgagtatcc ggacgactac acaggacctc gtgatggaga
    13861 atttaaaaca ccttatgcgg ttgtgcaact tcgtcaggat aatgcagctg gtagcctata
    13921 caatattgtt ggtttccaga cccacctcaa atggggagaa caaaagcgtg tcttccaaat
    13981 gattccgggt cttgaaaatg cggagtttgt ccgttatggt gtcatgcatc gcaattctta
    14041 catggattca ccaaatcttc ttgagcagac ttaccgttcc aagaaacaac caaatctctt
    14101 ctttgctggt cagatgacgg gggtggaagg ctatgttgag tcggcgactt cgggcttagt
    14161 tgcgggaatt aacgcagctc gtctcttcaa ggaagaaagc gaggttattt tccccgagac
    14221 gacagcgatt ggaagcttag ctcattacat tacccatgcc gacagcaaac atttccaacc
    14281 aatgaatgtc aattttggga tcatcaagga gttggaaggc gagcgtatcc gtgataagaa
    14341 ggctcgttat gaaaaaattg cagagcgtgc ccttgccgac ttagaggaat ttttgactgt
    14401 ctaatttttt tgaaagaatt gctcatgata ctataaaaat cttagaaatt gtgataaaat
    14461 aggtaggatg aaagaaggag agtgaaaatg gcgaatccca agtataaacg tattttaatc
    14521 aagttatcag gtgaagccct tgccggtgaa cgtggcgtag ggattgatat ccaaacagtt
    14581 caaacaatcg caaaagagat tcaagaagtt catagcttag gtatcgaaat tgcccttgtt
    14641 attggtggag gaaatctctg gcgtggagaa cctgcagcag aagcaggtat ggaccgtgtt
    14701 caggcagatt acactggaat gcttgggact gttatgaatg ctcttgtgat ggcagattca
    14761 ttgcaacaag ttggtgtcga tacgcgtgtg caaacagcca ttgctatgca acaagtggca
    14821 gaaccttacg tacgtggacg tgctcttcgc caccttgaaa aaggccgtat cgttatcttt
    14881 ggtgctggaa ttggttcacc ttacttctca accgatacaa cagcggctct tcgttcagct
    14941 gaaatcgaag cggatgccat tcttatggct aaaaatggtg tcgatggtgt ttacaatgcc
    15001 gatcctaaga aagataagac agctgttaag tttgaagaat tgacccaccg tgatgttatc
    15061 aacaaaggtc ttcgtatcat ggactcaaca gcttcaaccc tctcaatgga taacgacatt
    15121 gacttggttg tcttcaacat gaaccaacca ggcaacatca aacgtgtcgt atttggtgaa
    15181 aatatcggaa caacagtttc aaataatatc taagaaaagg aagaagaaag attatggcta
    15241 acgtaattat tgaaaaagct aaagagagaa tgacccagtc tcaccaatca cttgctcgtg
    15301 aatttggtgg tatccgtgct ggccgtgcca atgcaagctt gctcgaccgt gtacatgtag
    15361 aatactatgg agtcgaaact cctcttaacc aaatcgcttc aattacgatt ccagaagcgc
    15421 gtgttttgtt ggtaacacca tttgacaagt cttcattgaa agacatcgaa cgtgccttga
    15481 acgcttctga tcttggtatc acaccagcta atgacggttc tgtgattcgc ttgattatcc
    15541 cagttcttac agaagaaact cgtcgtgacc ttgctaaaga agtgaagaag gtcggcgaaa
    15601 atgctaaagt ggctgtccgc aatatccgtc gcgatgctat ggacgaagct aagaaacaag
    15661 aaaaagcaaa agaaatcact gaagacgaat tgaagactct tgaaaaagac attcaaaaag
    15721 taacagacga tgctgttaaa cacatcgacg atatgactgc caacaaagag aaagaacttt
    15781 tggaagtcta aaaataaaca gaaaaactca gttggcattg ctggctgagt tttattcgaa
    15841 agaaggaaat atgaatacaa atcttgcaag ttttatcgtt ggactgatca tcgatgaaaa
    15901 tgaccgtttt tactttgtgc aaaaggatgg tcaaacctat gctcttgcta aggaagaggg
    15961 ccaacataca gtaggggata cggtcaaagg ttttgcatac acggatatga agcaaaaact
    16021 ccgcctgaca accttagaag tgactgccac tcaggaccaa tttggttggg gacgtgtcac
    16081 agaggttcgt aaggacttgg gtgtctttgt ggatacaggc cttcctgaca aggaaatcgt
    16141 tgtgtcactc gatattctcc ctgagctcaa ggaactctgg cctaagaagg gcgaccaact
    16201 ctacatccgt cttgaagtgg ataagaaaga ccgtatctgg ggcctcttgg cttatcaaga
    16261 agacttccaa cgtctcgctc gtcctgctta caacaacatg cagaaccaaa actggccagc
    16321 cattgtttac cgtctcaagc tgtcaggaac ttttgtttac ctaccagaaa ataatatgct
    16381 tggttttatt catcctagcg agcgttacgc agagccacgt ttggggcaag tattagatgc
    16441 gcgcgttatt ggtttccgtg aagtggaccg cactctgaac ctctccctca aaccacgctc
    16501 ctttgaaatg ttggaaaacg atgctcagat gattttgact tatttggaaa gcaatggcgg
    16561 tttcatgacc ttaaatgata agtcatctcc agacgacatc aaggcaacct ttggcatttc
    16621 taaaggtcag ttcaagaaag ctttaggtgg tcttatgaag gctggtaaaa tcaagcaaga
    16681 ccagtttggg acagagttga tttagggaga tttatgagaa aatcatttta cacttggctc
    16741 atgaccgagc gcaatcctaa aagtaacagt cccaaagcta tcttggcaga cctagctttt
    16801 gaagaggcag cttttccaaa acacacagat gattttgatg aggtcagtcg ctttttggag
    16861 gagcatgcca gtttctcttt taacctagga gattttgaca gcatttggca ggaatatcta
    16921 gaacactagc atttattcat tgggtttgga ctagtaattt ctccatccct ctgctataat
    16981 aaaaagaaat aaaaggatta gagaggttct ttatttgaag gaacattcaa tagacattca
    17041 actgagtcat ccagatgacc tgtttcatct ttttggttcc aatgaacgcc atcttcgttt
    17101 gatggaagaa gagcttgatg ttgtgattca tgctcgtacg gagattgtcc aggttttggg
    17161 agaagagtct gcttgcgagg aagcccgtca ggttattcaa gctctcatgg ccttggtaaa
    17221 tcgtgggatg accgttggta cgccagatgt agtgacggct attagtatgg tcaaaaatga
    17281 tgaaatcgac aagtttgtcg ccctttacga agaagaaatc atcaaggaca atacagggaa
    17341 gcctatccga gtcaaaaccc tagggcaaaa gctttatgtg gacagtgtca aacagcatga
    17401 tgtgaccttt ggaattgggc cagcagggac ggggaagacc tttcttgcag ttattttggc
    17461 agtgactgcc cttaaacgtg ggcaagtcaa gcgaattatc ctaactcgtc cagcggtgga
    17521 agcgggagag agtcttggat ttcttccggg tgatcttaag gagaaggtgg atccttacct
    17581 tcgtcctgtt tacgatgcct tgtatcaaat tcttgggaaa gaccaaacga ctcgtctcat
    17641 ggagcgtgaa attatcgaaa ttgcgcccct tgcctatatg cgtggccgga ccttggatga
    17701 tgcctttgtc attctcgatg aggcgcaaaa cacgaccatc atgcagatga agatgttctt
    17761 gacgcgttta ggctttcatt ctaagatgat tgtcaatgga gatatcagtc agattgacct
    17821 gccacgtaat gtcaagtccg gtttgattga tgctcaagag aaactcaaga acatccatca
    17881 gattgacttt gttcattttt cagccaagga tgtggttcgc catccagttg tcgctcagat
    17941 tatccgagcc tatgaatatt ctactgaagt tgcacacgac tgattttgag gaagttcgcc
    18001 tgcaaaagaa tatactgttg agagaggaaa atccagttgt ataggctaaa ggttttatcc
    18061 aaaggtttga gacaacgatt aggcacgatg gaaagaactt ttatgtggct gatgacgatc
    18121 agtgcatctt cctgtgtcat aatcacaggg cacaagaaag taggaatttg aaaagatgat
    18181 tgaccaacta tctaagtatt acagttgtag gatactaact gaaaagaata ttccaagtat
    18241 tttatcttta tatgaaagta atcctctgta ttttcagcat tgtccaccag agccaaattt
    18301 tgcaactgta aaagaggaca tgctttgtct acctgaaggt aaagctaagg ctgataagtt
    18361 ttttattgga ttttggaatg gatctgacct tgtggctgtt atggattttg tctatgcaca
    18421 tcctgatgag gagactgttt ttattggttt gtttatggtt gatcaagcct atcagaggaa
    18481 agggattggt agtcatattg tgacagaagc actagcttat tttgctaaga actttcgaaa
    18541 ggcatgtttg gcttatgtta agggaaatcc gcaatctcag catttttggg aaaagcaggg
    18601 ctttaaatca attggatgcg aggttaagca agaactctat acggttgtta tcgttgaaca
    18661 gagcctagaa gattagaaat ggcatcaagt aagaactatt tggaatttgt tttggaacaa
    18721 ttatcaggat tagatgatgt gacttaccgt tccatgatgg gggagtatat tctttacttc
    18781 cgcggcaaga ttattgacgg catttatgac gatcgctttt tagttaaacc cgtgcaagca
    18841 gtcttagata agattgacca atcttctttt gagtttccat acaaaggtgc caaagaaatg
    18901 atttgagtgg aagaacttga taataagatg tttctataag acctgatttt agctatgtat
    18961 aaccaactgc caacgcccaa acctaaaaag aaaaagcaag ggtgaacgaa gtaaaaaaga
    19021 agtctgctaa ggccctgtct ttgcacgggt aaaattttat atataaaaag aagctgggac
    19081 taaagagctc agcttccttt ggtttatata attgtcatta caagacgaag tggttgggcg
    19141 aaactctgtt gactttattc aatttagagt ttcttatgca caattgagtc tggaacgaaa
    19201 gtctccagtt tcaaagtata cagtacaata aaccaacgat gtaatagctg atgacacaaa
    19261 gcacagtggg taggacttgt gaagtcaccc ttttcttttc aaaatttata ctaaatcatt
    19321 gatatcagtg tagtcacgat taagtccttg agcaactggt aggctagtca agtaaccttg
    19381 ataagtggtc acaccttgac gcaagccttc atcttcagag attgcttgtg cgaatccttt
    19441 gccagccaaa gcttcgatat aaggaagagt gacattggtt agggcgatgg ttgaagtgcg
    19501 ggtaaccgca ccagggatat tggcaacggc atagtggaga acaccgtgtt tttcatagac
    19561 gggttcatcg tgcgttgtca cacggtcagc tgtttcgata acgccacctt ggtcaacagc
    19621 aacgtcaacg atacagagcc tggacgcatt tgtttgacca tctcatctgt caccaattcc
    19681 ggtgcttttg caccagggat gagaatggct ccaatcacca catcagcatc tctcacactt
    19741 gcttcaatgt tgaatgaatt agacataaga gtttgaattt gacttccaaa gacttcttct
    19801 agaactgaga gacgcttggc actaatatct aaaatagtca cttgagcacc aagaccaagg
    19861 gcgatgcggg cagcatgtgt accgacgaca ccaccaccga tgatagttac ttttcctttt
    19921 ggaacacctg gtacaccacc aggtagaaca ccagagccac cagcttgctt agtaaggaag
    19981 tgagctccga tttgaacagc catacgacct gcaacctcac tcataggaac gaggagcggt
    20041 agttgtcctt gattgtcacg aacagtttca taggcaattc ctgttgtttt tgctgctaac
    20101 atagcatctg ctaattctgg agcagcggcc atgtgcaagt aggtgaagag aagaagatcg
    20161 tcgcgcaagt aaccgtattc agaacttaaa ggttctttta ctttcacaac caactctgct
    20221 gcccaagctt caccagcagt agcgacaatc tcagctcctt gcttttgata gtcagcatca
    20281 gtaaagccag aactgagacc agcatttgtt tcgataagga cacgatgacc acgactaact
    20341 aagctatgaa cacctgcagg tgtgagggcg acacggtttt cgttattttt aatttctttt
    20401 gggattccga ttaacattga gataacctac ctttcaattg acggtcttgt tttggttgtc
    20461 acattccagt tcataaatca aaaatgtgac ggtttcattg tatatgaaac cgcttcaaaa
    20521 atcaagaaaa acttgtcatc caaatttttt tatgctagac tagtgaaaat caagctctaa
    20581 tggagggaaa agtatggaat caatatttgt gaaatttgcc cagtatccgt ctatagaaac
    20641 ggagcgttta ttgcttagac ctgtaacttt ggatgatgcg gaagcaatgt ttgactatac
    20701 ctcggacaag ggtaatacac gttacacttt tccaaccaat caaatcttgg aagaaaccaa
    20761 gaataacatt gctcagttct acttggctaa tcccttggga cgttggggga ttgaattaaa
    20821 agataacggc aagtttatcg gaactattga cttacacaag attgaccctg ttcttaagaa
    20881 ggcagctatt ggctatatta tcaataaaaa gtattggaat caaggattga cgccagaaac
    20941 caatcgtgct gtgattgagc tagcttttga gaagatagga atgaataagt tagttgcttt
    21001 atacgataag gacaatcctg cgtcaggaaa ggtcatggag aaatcaggca tgcgtttttc
    21061 ccatgcagaa ccatatgctt gtatggacca gcatgaaaaa ggccgaatcg tgacaagagt
    21121 tcattatgtc ttgaccaagg aagactattt tgcaaataaa taagcagttg aaaagaaatt
    21181 ttcgactgtt ttttcttcct cttacgaata atctaagaga ggagaaaata tggaagcaat
    21241 tatcgagaaa atcaaagagt ataaaatcat cgtcatctgt actggtctgg gcttgcttgt
    21301 aggcggattt ttcctgctaa agccagctcc acaaacacct gtaaaggaaa cgaatttgca
    21361 ggctgaagtt gcagctgttt ccaaggattt ggtatccgaa aaggaagtga acaaggaaga
    21421 gaaggaagaa ccagttgaac aagatctaat cacagtagat gtcaaaggtg ctgtcaaatc
    21481 gccagggatt tatgacttgc ctgtaggtag tcgagtcaat gatgctgttc agaaggctgg
    21541 tggcttgaca gagcaagcag acagcaagtc gctcaatcta gctcagaaag ttagtgatga
    21601 ggctctggtt tacgttccta ctaagggaga agaagcagtt agtcaacaga ctggttcggg
    21661 gacagcttct tcaacaagca aggaaaagaa ggtcaatctc aacaaggcca gtctggaaga
    21721 actcaagcag gtcaagggac tgggaggaaa acgagctcag gacattattg accatcgtga
    21781 ggcaaatggc aagttcaagt cagtagacga gctcaagaag gtctctggca ttggtgccaa
    21841 gaccatagaa aaacttaaag actatgttac agtggattaa gaatttctct attcccctaa
    21901 tttacctgag ttttctgtta ctatggcttt actacgccat tttctcagta tcctattttg
    21961 ctttgttggg ttttgttttt ctgctagtct gcctctttat ccaatttcct tggaaatcag
    22021 caggtaaagt tctagtgatt tgtggagtct ttggcttctg gtttctgttt caaacttggc
    22081 aacagagtca agcgagtcaa aatctggcgg attctgttga aagggtacgg attttaccag
    22141 acactattaa ggtcaacggt gacagtctgt cctttcgtgg taagtctgat ggtcgtgctt
    22201 tccaagtcta ttataaactc cagtccgagg aggagaaaga agcctttcaa gctttaaccg
    22261 acctgcatga gataggacta gaagggaagc tttcggagcc agaagggcag agaaattttg
    22321 gtggctttaa ttaccaagcc tatctgaaga ctcagggaat ttaccagact ctcaatatca
    22381 aaacaatcca gtcacttcaa aagattggca gttgggatat aggagaaaac ttgtccagtt
    22441 tacgtcgaaa ggctgtggtt tggattaaga cgcactttcc agaccctatg cgcaattaca
    22501 tgacaggact cttgctggga catctggaca ccgactttga ggagatgaat gagctttatt
    22561 ccagtctagg aattatccac ctctttgccc tatctggcat gcaggtaggt tttttcatga
    22621 atggatttaa gaaacttctc ttgcgattgg gcttgaccca agaaaagttg aaatggttga
    22681 cttatccctt ttcccttatc tatgcgggac taactggatt ttcagcatcg gttattcgca
    22741 gtctcttgca aaagctactg gctcaacatg gggttaaggg cttggataat tttgccttga
    22801 cggtgcttgt cctctttatt gtcatgccaa actttttctt gacagcagga ggagtcttgt
    22861 cctgcgctta tgcttttatc ctgaccatga ccagcaaaga aggggagggg ctcaaggctg
    22921 ttgctagtga aagtctagtc atctccttgg gcatattgcc cattctatcc ttctattttg
    22981 cggaatttca accttggtct atccttttga cctttgtctt ttcctttcta tttgacttgg
    23041 tcttcttacc gctcttgtcc atcttatttg ccctttcctt tctctatcca gtcattcagc
    23101 tgaattttat ttttgaatgg ttggagggga tgattcgctt ggtatcacag gtggcaagta
    23161 ggcctctagt ctttggacaa cctaatgcgt ggcttttaat tttattgtta atttccttgg
    23221 ctttagtcta tgatttgagg aaaaacatta aaaggctagc agtgttgagc ttattgatta
    23281 caggtctctt tttcctgacc aagtatccac tggaaaatga aatcaccatg ctggatgttg
    23341 ggcaagggga aagtattttc ctacgggatg taactgggaa aaccattctc atagatgttg
    23401 gtggcaaggc agaatctgag aagaaaatcg aaaaatggca agaaaaggcg acgaccagca
    23461 atgctcagcg aaccttgata ccctatctta aaagtcgagg agtgagcaag attgaccagc
    23521 tgattttgac aaatacggac aaggagcata ttggagattt gttggaggtg accaaggctt
    23581 tccatgtagg cgaaatttta gtgtcaaaag gcagtctgaa acagaaggaa tttgtggtag
    23641 aactacaggc gactcaaaac aaagtacgta gtgtgtcagt gggagagaac cttctaattt
    23701 ttggaagtca gttagaagtc ctatccccaa ggaaaattgg agatggcggt catgatgata
    23761 ccctggttct gtatgggaaa ctcttggata agcaatttct cttcactgga aatttggagg
    23821 agaaaggaga gagagacttg ctgaggcaat atcctgacct agaagtggat gttttgaaag
    23881 ctagccaaca tggctctaaa acctcatcaa gttcagcgtt tttagaaaaa ctcaaaccag
    23941 agattaccct catctcagtt ggaaagagta atcggacgaa actcccccat caggaaacat
    24001 tgacacgact ggaaactatc aatagcaaag tttatcgaac tgatcagcaa ggagctatac
    24061 gctttaaggg gtggaaaagt tggaaaatcg aaagtgttcg ataggaagga caaatattat
    24121 atattagtaa aataaactaa aaatctgttg cataataatg ataaaaacga tataatgaaa
    24181 gcgtcttcga tattgatgat ataaaatcat taaaaatcag caaaagttgt tttattagct
    24241 agtttgttat ctattggtct ttttcagtcc agtgtatctg ctgtgagcgt tcttaaaact
    24301 tatcggtatg attggaatat cttctataag tctagtatga attatcacag acatagatat
    24361 agtgatattc cgtcatggtc tcgttattac agctattctg agtataaagt tggcggaggc
    24421 tggaactatg atcgttatga ggtaataaac tactacagcg gaggctatta atccttaaag
    24481 agtgataaaa aggagggcta ggtatgttgc agcttactca tgtgacctta aaaacgcgac
    24541 aagtcatctt acaagatgtt gattttacat ttgaaaaggg taggatttat ggtattcttg
    24601 ctatcaatgg ttctggaaag acgacactat tccgcaccat tagcaattta attcctataa
    24661 gtagcggaaa tattgcagcc cctccttctt tattttatta tgagagcgtt gaatggctgg
    24721 atggaagctt aagtgggata gactatcttc gccttatcaa aaacatctgg aagtcagacc
    24781 tgaacttgag ggatgaaatt gcctattggg aaatgtctga ctatatcagc cttcccattc
    24841 gcaagtattc cttaggcatg aagcaacgct tggtgattgc catgtatttc ctcagtcagg
    24901 ccaaatgctg gcttatggat gagattacaa atggcttaga tgagtattat cgacagaagt
    24961 tttttgatag gcttgcacaa atcgatagac aagagcagct ggttctttta agttcccact
    25021 ataaggaaga gttggttgat gtctgcgata gagtagtaac cattcatcag gggcagatag
    25081 aagaggttcc gttatgaaag atgttagtct atttttattg aaaaaagttt tcaaaagccg
    25141 cttaaactgg attgtcttac ttttatttgc atctgtactt ggtgttacct tttatttaaa
    25201 tagtcagact gcaaactccg tcagcttgga gagtaggttg gaaagtcgca ttgtggataa
    25261 cgggagagcc atcaatgaaa atgaagcgaa actttcccaa atgtctgaca ccagctcgga
    25321 ggaataccag tttgctaaaa ataatttaga cttgcaaaaa aatcttttga cgcgaaagac
    25381 agaaattctg actttattaa aagaagggcg ctggaaagag gcctattatc tgcagtggca
    25441 agatgaagag aagaattatg aatttgtatc aaatgacccg actgctagct ctggcttaaa
    25501 aatgggggtt gaccgcgaac ggaagattta ccaagccctg tatcccttga acataaaagc
    25561 acatactttg gagtttccga cccacgggat tgatcagatt gtctggattt tagaggttat
    25621 catcccaagc ttgtttgtgg ttgcgattat ttttatgcta acacaactat ttgcagaaag
    25681 atatcaaaat catctggaca cagctcactt atatcctgtt tcaaaagtga catttgcaat
    25741 atcctctctt ggagttggag tgggatatgt aactgtgctg tttatcggaa tctgtggctt
    25801 ttcttttcta gtgggaagtc tgataagtgg ttttggacag ttagattatc cctacccgat
    25861 ttatagctta gtgaatcaag aggtaactat tgggaaaata caagatgtat tatttcctgg
    25921 cttgctctta gctttcttag cctttatcgt cattgtggaa gttgtgtact tgattgctta
    25981 ctttttcaag caaaaaatgc ctgtcctctt tctttcactc attgggattg ttggcttatt
    26041 gtttggcatc caaaccattc agcctcttca aaggattgca catctgattc cctttactta
    26101 cttgcgttca gtggagattt tatctggaag attatctaag cagattgata atgtcgatct
    26161 aaattggagc atggggatgg tcttacttcc ttgcctgatt atccttttgt tagtggggat
    26221 tctatttatc gaaagctggg gaagttcacg taaaaaggaa gtttttaata ggtcttagct
    26281 ttcctatagg gaaaataagt aaaaactaac atagagaggg aatcaatttg attctctctt
    26341 tttgattcga aaaccaaacc aaaatacaaa cagaaacttt tcaaaaaaat aactgtaagt
    26401 gtctagagtt ttgagaaatg cagaaagaat ataaataaat gtagagaacg aaaaaatccg
    26461 ttctcttttt tcgttgccaa aaattaagga gaaaaaatgt cagataatat tgaaattgtt
    26521 atggatattg attcgctaga aattttcgat gtaatagatc ttgataagaa tgaaaatatg
    26581 gttgattgta tttctgaagg aaattctgat gaaaagtatc tccagacaat gaccttgcta
    26641 gagtttggct tggaaacgat tattataagc tcgctagtat tttatggaaa gtcataaaag
    26701 atgatgttat tcatgaatta tatcttagaa ttaagcttgg cacttatccg tatttcagaa
    26761 gagctagaga tggaacatgg ggaatgggga caaaccagcc aactgactta tgatgaaggc
    26821 ctgtagacga cgatggaatt tactcctgag ttacttgctt ctgtttgaaa cgagagaggc
    26881 cgagatagca tgacaagact agaaagagaa atgttgaatt attataagcg ttcactggag
    26941 ctatatgagg caagactaga agtcttaaga aaaccttaca aaaaagtgag gtacaactaa
    27001 tgagtgcaga acgtgatctt gtgagaaaga aaatcaagga atttaagttc aagataggcg
    27061 aattagaagg aacattggaa gggagttaat ccatgtggtt ggaaacaatc gtttgttttg
    27121 attgtgatta tgaggaaaaa tgggaagaag ataatatttt caagcctatt cattgtcctg
    27181 aatgtagaga tgtattagat gttgtagaaa gagattggtt aggtgaaaca atacttagaa
    27241 gcacagtgca gtgtgagcga tgtaactttt tatttgacca tttggatttt cagcttggtc
    27301 tatctgaatg tccgagttgc ttttcaaagg agctcaaatt agtgagacag aaaaaggaga
    27361 tagtagaatg actaaagaaa tgtttgtgca attttcaaaa aaagcagctg ttaacgaagt
    27421 gatgagaaaa acaggaatga gtaaaaaacg tgctgttaag gcggttgaag aattagagag
    27481 agaaggagtt ctgttctcta tgggaaatgg tactgtgatg atgggggtgt gataacatgg
    27541 ctgatattac agtaaatcaa gtggcaacac agaccttcta tcaaatccca caaattttca
    27601 tggtaaatgt taagaagaaa ttttctgctg aagggaaacc tactgggaaa atcaagatga
    27661 cgagtctcta tgccaagaaa ttatcaaatg atggcaaaat tgcttatggt gtactctatg
    27721 atcgatgtat gttgagtatt tattcttaca gaaacggtga actgacttat gttgatgaga
    27781 atggttcagt atttcttgtc tatacggttg aggacttaat ggaaatttta gatcgtagta
    27841 agccaactgt gttgaaaatc aagaaagaat tgaaagagct tggcttgctt cgtgaagtga
    27901 aacaagggaa gaatcgtccg aatcgtttgt atctgcaaaa tgtgaatgct gaattacaag
    27961 aatatgaaca ctatgatgct gaagtcgtag aaaaaggacg tgacaaagga actgtagtct
    28021 accaccatgt aaaaacttta gattacaaag gttgtgtctt atttgaaatt gaacgtccag
    28081 gcagtgaaga agaatcttct attttgaaag atgaaaactc tgttttagaa aagcctatca
    28141 aatcaataaa ttctggaagt caaaaatctt tacctccgga ggtaaaaaat tttaacccta
    28201 ttaagactga gaagagtcat actgagaata atagtactag acatagttct agaaagcctg
    28261 cttccaattc taaggaattg gatcagactg ctggaacttg tgacactcct tctcaaaaaa
    28321 caagtgggaa gaaatttatc aaacctcaag tctattctct cttgcaggaa attgcagata
    28381 gctaccgaga tcatttaccg tggtaccagc attataatat gactcaccgc caaaagatga
    28441 ttgttggcca atacattcag acaggatgga taacaagtag tgaggttctt cactgtatcg
    28501 aacggattcc tgaatgtgat agtccttttg cttacttgat tcaatctatt gaaaatttga
    28561 ttggcgaacg taagagcgag gccaagatgc aagctcatag agaagcagag tataggtatc
    28621 tgagtaacta agctatagat gacatgagac taaatctagc ttttttgacc tgagcaagtc
    28681 ataaaactac ttttgacctt tgaaaattga atatccccac tgtcctgatt agcggaacta
    28741 agcataaaaa gaagaacaag ggcggtgtgt aggctagaaa aggatatcta gtgctgttcc
    28801 accacgtaaa agcaggcaaa gcctaagctg aaggagtttg cggtttctag acttaaaacc
    28861 gtgtgtaaaa aatacagcag gtatgtacgt catacctcgg catggctgta aatcagcctt
    28921 gattcagtaa ggaggagata agatgaatca atcaaaatta gttacagagg tcactttagc
    28981 tgaccttaga cgcttaggaa atcaaggaaa tgcaaccgca agacttgata atggcgatga
    29041 aatcaaatta accagcagat atggtttggt acctaaaaaa ggatatttag caggtaaact
    29101 agaaacagtt tggatgattg tagaatattc aaaaatttat aaagaaattc gcaccatcaa
    29161 acgaggtgat gttttagtgg ttagacgcat taagcaagga aataccaatc gtttactgct
    29221 gactggtaaa ggatatcatc gtccaacgaa gcattaaaca gatagagcct catctatctg
    29281 tttcatcaag gagaggagat ttgaactgtt ttaaacgtcc tatctttgat taagcggata
    29341 gatgaatgaa aattaagaaa aaaattgaga acaacctcta aaaatggtaa aataaaagta
    29401 taaaataaat attttaagaa cgtttttaaa caaaaaggag ataagattat gaaattgaga
    29461 acaaccatct tggcaacaac tgctagcgta acgttgcttg ggttaggaaa tagtcaacct
    29521 gtgtatgcaa atagtacaac gagtagtcaa gtagagagct taaaaagtga atttattaaa
    29581 gcaaagagag aatatgaaca agctaaaagt atctatgaca atgctttatc atcttcacct
    29641 agcaatacga ttatactgag tgataagtat ataaaggctt tgaagacggc tttttctgat
    29701 tttaatatta gccagactga acgtgacagt gcgaaatcta ttttgcagtc agaaagtttg
    29761 agattaaaga atcaaaatag tttccacaaa gatgttgctg atgagggaga acgtctggat
    29821 gtcaacaatc taccgctagc tgttcgtcag gagttgtcat tttttgccca agatttaatt
    29881 aaccaagttc gttctcaggt tgggacacct agagtcagtg tttcaatttc ggcacttgac
    29941 tttgcagata aggtggcgaa agcatatgtt caagataact ggggttggca taaaatgagc
    30001 gtatctggta cacttggtca tgatgcgact ggaatcaatc atgtggcgag agaatatgga
    30061 ctgcctacaa ccaattctga agaagagaaa aaaggggagc aaaactatga aaatctagct
    30121 tctcgtctac ctggtttcaa aacagctaac aaggctcagt taaaagaggc tatctatatt
    30181 gggatgatag agtttatgtt caatgatact gagtggatgc atgctcagag tattgctggc
    30241 ttgaactggg gaaatgtgaa ctcaaaagat tattttgggc tttcattctc tagtcgttct
    30301 tctgttagtt cagcccattt tatcacggtt tcccaagaag atatcaagcg tgcaagcaaa
    30361 tcaagcttta gcacggctgc tgtgagtgat ccaactagtg tcaatcgccg tcaagcaatc
    30421 aaaaagctag aggaagacta caaagccaag gaaaaaattt atcaagattt tcaaaaacaa
    30481 gcagatagta aaggatctca agggcagtct aaccaaggtt cagctactgt gacagaacca
    30541 agtaaaccaa gcgctggctc agctgagcct actaaatcga ttgaaaacac atctgatttg
    30601 cgtgaccaat ggaaacaaga gggaagttat tggtattatt ttgatcgtgc agggaaagct
    30661 cttgttaata gttggaaggg aaactattat ctcaaatcaa atggtgtgat ggcacgtaat
    30721 gaatgggttt atgatacaaa ctataaagct tggtattatt tcaaatcaga tggaagctat
    30781 gcacaaaata gttggcaagg aagttactac cttaagtcag
//
LOCUS       DAVDHZ010000025        29000 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000025 DAVDHZ010000000
VERSION     DAVDHZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.025"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            283..780
                     /locus_tag="VUR46_001332"
     CDS             283..780
                     /locus_tag="VUR46_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET5456751.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            780..2435
                     /gene="dnaX"
                     /locus_tag="VUR46_001333"
     CDS             780..2435
                     /gene="dnaX"
                     /locus_tag="VUR46_001333"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET5456752.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2463..2657
                     /locus_tag="VUR46_001334"
     CDS             2463..2657
                     /locus_tag="VUR46_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET5456753.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2807..3577
                     /gene="sufC"
                     /locus_tag="VUR46_001335"
     CDS             2807..3577
                     /gene="sufC"
                     /locus_tag="VUR46_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET5456754.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDMVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3605..4867
                     /gene="sufD"
                     /locus_tag="VUR46_001336"
     CDS             3605..4867
                     /gene="sufD"
                     /locus_tag="VUR46_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET5456755.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIESLELPVIERVKFH
                     RWNLGDGTITESEPSANVPDFTALDNHLKLVQVGTQTVFEQIPVELAQQGVVFTDFHS
                     ALEEIPELIEELFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEIKEPIEGVFYQDS
                     DSDVPFNKHIMIIAGKNSKISYLERLESRGEGSTKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQIQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4878..6104
                     /locus_tag="VUR46_001337"
     CDS             4878..6104
                     /locus_tag="VUR46_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5456756.1"
                     /translation="MLDVEVIRKDFPILDQIVNDEPLVYLDNAATTQKPLAVLETINR
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     YAEEVLTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMVDLRAKLTD
                     KVQFVSLAHASNVLGVVNPIKEITQMAHQVGAIMVVDGAQSTPHMKIDVQDLDVDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MVGAIGLAAAVDYLEKIGMDAIEAHEQELIAYVFPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLDVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            6091..6531
                     /locus_tag="VUR46_001338"
     CDS             6091..6531
                     /locus_tag="VUR46_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET5456757.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFNAEDRLEDIAFLNSGCTISTASASMMTEAVLGKTKQEILELATIFSEMVQGQ
                     KDDRQDSLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6589..8001
                     /gene="sufB"
                     /locus_tag="VUR46_001339"
     CDS             6589..8001
                     /gene="sufB"
                     /locus_tag="VUR46_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET5456758.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEDVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDEVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFEKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANVGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSKVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8232..9473)
                     /locus_tag="VUR46_001340"
     CDS             complement(8232..9473)
                     /locus_tag="VUR46_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET5456759.1"
                     /translation="MKKIFLTLLTISLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLRDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLESMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVAHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9576..10685
                     /locus_tag="VUR46_001341"
     CDS             9576..10685
                     /locus_tag="VUR46_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET5456760.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVRVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11331..11678
                     /gene="ssrA"
                     /locus_tag="VUR46_001342"
     tmRNA           11331..11678
                     /gene="ssrA"
                     /locus_tag="VUR46_001342"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11848..11935)
                     /locus_tag="VUR46_001343"
     tRNA            complement(11848..11935)
                     /locus_tag="VUR46_001343"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11899..11901),aa:Ser,seq:gga)
     gene            12097..12837
                     /locus_tag="VUR46_001344"
     CDS             12097..12837
                     /locus_tag="VUR46_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5456761.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQGIKEKTEVIEV"
     gene            12834..13745
                     /gene="pfkB"
                     /locus_tag="VUR46_001345"
     CDS             12834..13745
                     /gene="pfkB"
                     /locus_tag="VUR46_001345"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET5456762.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13742..15694
                     /locus_tag="VUR46_001346"
     CDS             13742..15694
                     /locus_tag="VUR46_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5456763.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15858..18083
                     /locus_tag="VUR46_001347"
     CDS             15858..18083
                     /locus_tag="VUR46_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET5456764.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(18127..18555)
                     /locus_tag="VUR46_001348"
     CDS             complement(18127..18555)
                     /locus_tag="VUR46_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456765.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITATITIMN
                     ALDNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVKE
                     EKKEEQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ"
     gene            18693..19835
                     /locus_tag="VUR46_001349"
     CDS             18693..19835
                     /locus_tag="VUR46_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5456766.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHLAVK
                     ESALWLKSQGFEVDFAPVDKKGFVDVEALADLIRPDTTLVSIVAVNNEIGSVQPIEAI
                     SELLADQPTISFHVDAVQALAKIPTEKYLTERVDCATFSGHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFIFSAEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19844..21058
                     /gene="thiI"
                     /locus_tag="VUR46_001350"
     CDS             19844..21058
                     /gene="thiI"
                     /locus_tag="VUR46_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET5456767.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVR
                     ADRDRAHAHLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21194..22018
                     /locus_tag="VUR46_001351"
     CDS             21194..22018
                     /locus_tag="VUR46_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5456768.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGHSWKIIPAIKRNSDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     KSPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            22040..22780
                     /locus_tag="VUR46_001352"
     CDS             22040..22780
                     /locus_tag="VUR46_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET5456769.1"
                     /translation="MHIEYLSHWSGHLNREMYLNRYGHAGIPVVVFASSGGSHNEYYD
                     FGMIDACTSFIEEGRVQFFTLSSVDGESWLATWKNAHDQAEMHRSYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYYNDDAI
                     YQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDKKQIPAW
                     FAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            22793..23959
                     /locus_tag="VUR46_001353"
                     /pseudo
     CDS             22793..23959
                     /locus_tag="VUR46_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
     gene            24467..25432
                     /locus_tag="VUR46_001354"
     CDS             24467..25432
                     /locus_tag="VUR46_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET5456770.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDTV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLTNPPFKGSLDYNSTYNDLLATVKTKKQNYSFFLFSCEL"
     gene            25420..25959
                     /locus_tag="VUR46_001355"
                     /pseudo
     CDS             25420..25959
                     /locus_tag="VUR46_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819381.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            25972..26557
                     /locus_tag="VUR46_001356"
                     /pseudo
     CDS             25972..26557
                     /locus_tag="VUR46_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            26617..26853
                     /locus_tag="VUR46_001357"
     CDS             26617..26853
                     /locus_tag="VUR46_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET5456771.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            26850..27263
                     /locus_tag="VUR46_001358"
     CDS             26850..27263
                     /locus_tag="VUR46_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET5456772.1"
                     /translation="MTIYLTEKQIEKINSLAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27381..28335
                     /locus_tag="VUR46_001359"
                     /pseudo
     CDS             27381..28335
                     /locus_tag="VUR46_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            28369..>29000
                     /locus_tag="VUR46_001360"
     CDS             28369..>29000
                     /locus_tag="VUR46_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5456773.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLREQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSE"
BASE COUNT         8780 a         5207 c         6331 g         8682 t
ORIGIN      
        1 ttgtgtgtat ctttattgat gatatctaga atcttgatgt ttgggtcttt aatatcgagc
       61 agttttgtga taaaatgtaa ttgttccata tgattctttc taatgagttg ttttgtcgct
      121 tttcattata ggtcatatgg gacttttttt ctacacaaaa ataggctcca taatatccat
      181 agggaattta cccactacaa atattataga gcccaaaatc ctttgtttac taaacaaggg
      241 atttttcttt tgtctctgct ccttttttga tataatagtt ctatgttaaa atcagaaaaa
      301 caatcacgtt atcaaatgtt aaatgaagaa ttgtccttcc tattggaagg cgaaaccaat
      361 gttttggcta atctttccaa cgccagtgct ctcataaaat cacgttttcc taataccgta
      421 tttgcaggct tttatttgtt cgatggaaag gaattggttt taggtccctt ccaaggaggt
      481 gtttcctgca tccgtattgc actaggcaag ggtgtttgtg gtgaggcagc tcactttcag
      541 gaaactgtta ttgttggaga tgtgacgacc tatctcaact atatttcttg tgatagtcta
      601 gctaaaagtg aaattgtggt gccgatgatg aagaatggtc agttacttgg agttctggat
      661 ctggattctt cagagattga ggattacgat gctatggatc gagattattt ggaacaattt
      721 gtcgctattt tgcttgaaaa gacagcatgg gactttacga tgtttgagga aaaatcttaa
      781 tgtatcaagc actttatcga aaatatagaa gtcaaaactt ctcccagtta gttggtcaag
      841 aagttgtggc taagactctt aaacaagcgg tggagcaaga gaaaataagt cacgcttatc
      901 ttttttctgg tcctcgtgga acgggaaaaa ccagtgttgc taaaatcttt gccaaggcta
      961 tgaactgtcc caatcaagtg ggtggcgaac cttgcaataa ctgctatatt tgtcaagcag
     1021 tgacggacgg tagtttagaa gatgtcattg aaatggatgc agcttctaat aatggggtag
     1081 atgaaattcg cgaaattcgt gataaatcta cctatgcgcc tagccttgct cgttataagg
     1141 tttatatcat agatgaggtt cacatgctgt ctacaggggc ttttaatgcc ctcctaaaga
     1201 cgctggaaga accaacacag aatgtagtct ttattttggc cactactgaa ttgcacaaga
     1261 ttcctgctac tattctatcc cgtgtgcaac gttttgagtt taaatcaatt aagacacagg
     1321 atattaagga acatattcac tatatcttag aaaaagaaaa tatcagttct gaaccagagg
     1381 ctgtggaaat cattgccaga cgggcggaag gtggaatgcg ggacgccttg tctattttgg
     1441 atcaagccct gagtttgaca cagggaaatg agctgacgac tgctatctct gaagaaatta
     1501 ctggcaccat tagcctatca gccttggatg attatgtggc ggccttgtct caacaggatg
     1561 ttcccaaagc tttgtcttgc ttgaatcttc tttttgacaa tggtaagagc atgactcgtt
     1621 ttgtgaccga tcttttgcac tatttaagag acttgttaat tgttcaaaca gggggagaaa
     1681 atactcatca tagttcagtc tttgtagaaa atttggcact tcctcaaaaa aatctgtttg
     1741 aaatgattcg cttagcaaca gtgagtttag cagatattaa gtctagtttg cagcccaaga
     1801 tttatgctga aatgatgacc gtccgtttgg cggaaatcaa gccagaacca gctctatcag
     1861 gagcggttga aaatgaaatt gctacgctga gacaggaagt tgcccgtctc aaacaagagc
     1921 tttctaatgt aggtgcggtt cctaaacaag ttgcaccagc tcctagtcga ccagctacgg
     1981 gcaaaacagt ctatcgtgtc gatcgtaata aagtgcaatc tatcttacaa gaggccgtcg
     2041 aaaatcctga tttagcacgt caaaatctaa ttcgtttgca gaatgcctgg ggagaggtaa
     2101 ttgaaagtct aggtgggccg gacaaggctc tgctagttgg ttctcaaccg gttgctgcca
     2161 atgaacacca tgctattctt gcttttgagt ctaacttcaa tgctggtcaa actatgaaac
     2221 gagacaatct caataccatg tttggtaata tcctcagtca ggcggcaggt ttttcacctg
     2281 agattttagc tatttccatg gaggaatgga aagaagttcg cgcagccttt tcagccaaag
     2341 ccaaatcttc tcaaactgaa aaagaagtag aagaaagcct gattccagaa ggatttgaat
     2401 ttttggctga taaagtgaag gtagaggaag actaaagaaa gatttcatga tacaataagt
     2461 ttatgaataa acaacaattt attattatgg cgctgtttac agctgctgag acctattttt
     2521 tcaatgaagc ctggatgact ggccgctata ttatggcagc cttttgggca attttactct
     2581 ttagaaattt ccgagtcagt tatgtgatgg gtaaaatcgt tgatgtcatc gatcagcatt
     2641 ttaataggaa agactagccc tcagcttcca gacaaaatca aagcctttta ggcttttttt
     2701 tgttatacta gaaaagtata tttatagaat ttttgctcta tttctgggga aatcagacgt
     2761 ttttctagta agtactgtaa aagttttgaa aaagaaagga actattatgt cagtaataga
     2821 gatcaaagat cttcacgttg agattgaagg aaaagaaatt ttaaaagggg ttaacctgac
     2881 cctgaaaaca ggagaaattg ccgctatcat gggaccaaat ggtacaggta aatcgactct
     2941 ttctgccgct atcatgggaa atccaaacta tgaagtaact aaaggtgaag ttttgtttga
     3001 tggcgtaaac atccttgagt tggaagtgga tgagcgtgcg cgtatgggac ttttccttgc
     3061 tatgcaatac ccatcagaaa tccctggaat taccaatgct gagtttcttc gtgccgctat
     3121 gaatgcgggt aaagaagatg atgagaagat ttcagttcgt gagtttatta ctaagctaga
     3181 tgaaaaaatg gaattgctca acatgaaaga agaaatggca gagcgttacc tcaacgaagg
     3241 cttctctggt ggtgagaaaa aacgcaatga aattcttcaa cttttgatgc tggagccaac
     3301 atttgctctt ttggacgaga ttgactcagg tcttgatatt gacgctctta aagttgtgtc
     3361 taaaggtgtc aatgccatgc gtggtgaagg ttttggtgct atgatcatta ctcactacca
     3421 acgtcttttg aactatatca cacctgatat ggtacacgtg atgatggaag gtcgtgttgt
     3481 cctttctggt ggtccagaat tggctgcgcg tttggaacgt gaaggatacg caaaattagc
     3541 tgaagaactt ggctacgact acaaggaaga attgtaattc cctcgtatct tttaggagaa
     3601 gtaaatgact agagaaaata ttaaactttt ttcagaaatg cacgctgaac caagctggtt
     3661 ggctgatctc cgtcaaaaag cttttgataa aatcgagagt ttggaattac cagttattga
     3721 gcgtgtgaaa tttcaccgtt ggaatctggg tgatggaacg attacagaaa gtgagccatc
     3781 agcaaatgtt ccagatttca ctgcactaga taatcacttg aagttggtgc aagtaggaac
     3841 tcaaactgtt tttgagcaaa ttccagttga gttggctcaa cagggtgttg tatttacaga
     3901 cttccattca gctttagaag aaattccaga gcttattgag gaattattca tgtcatctgt
     3961 caagtatgac gatgataagt tggcagccta ccatacagct tatttcaaca gtggtgctgt
     4021 tctttacatt cctgataatg ttgagattaa agaaccaatc gaaggtgttt tctaccaaga
     4081 cagtgatagc gatgtaccgt ttaacaagca tattatgatt atcgctggta aaaattctaa
     4141 gattagttat ctggagcgtt tagagtcacg tggtgaagga agtacaaaag caactgcaaa
     4201 catcactgtc gaagtgattg cacgttctgg tgctcaagtg aagtttgctg ccatcgaccg
     4261 tctaggtgaa aacgttactg cctacattag ccgtcgtggt aaattaggca atgatgcaag
     4321 cattgactgg gcaatcggtg tcatgaacga agggaacgtc gttgcggact ttgatagcga
     4381 cttgattgga aatggtagcc atgctgacct gaaagttgta gctctttcaa gtggccgtca
     4441 gatacaaggg attgataccc gagtgactaa ctatggttgc aactcaatcg gaaatatcct
     4501 tcaacatggg gttattcttg aaaaagcaac cttgaccttc aatggtattg gccacattat
     4561 caagggtgcc aagggagcag atgcgcaaca agaaagtcgt gttctcatgc tttcagacca
     4621 agcgcgttca gatgccaatc caattctttt gattgatgaa aatgacgtaa ctgcaggaca
     4681 tgcggcttct atcggtcagg tagatccaga agacatgtac tacctcatga gtcgtggttt
     4741 ggacaaggca actgcagagc gtttggttgt tcgtggtttc cttggatccg ttatcgttga
     4801 gattccagtc aaggaggttc gtgatgaaat gattgcgact atcgaagaaa aattgtcaaa
     4861 acgctaaggg gtagcctatg ttagatgtag aagtgattcg caaggatttt ccaattttag
     4921 accagattgt taatgatgaa ccattggttt atttggacaa tgctgcgacg acacaaaaac
     4981 cactagcagt tctggaaaca atcaaccgct actatgagca ggacaatgcc aatgttcatc
     5041 gtggcgttca taccttggca gaaagggcga cagcttctta tgaggcagct cgtgaaacca
     5101 ttcgtaagtt tatcaatgca gggtctacaa aggaagttct ctttactaga ggaacgacaa
     5161 ccagtcttaa ctgggtagcg cgttatgctg aggaagtctt gactgaggga gaccaggttt
     5221 tgatttctgt catggaacac cattctaata tcattccttg gcaggaagcc tgccgtaaga
     5281 ctggagcgga gcttgtctat gtttatctca aagacggagc tttggatatg gttgacttgc
     5341 gagcaaaatt gacggacaag gtacagtttg tttccctagc tcatgcctca aatgttctgg
     5401 gtgtggtcaa tccgatcaaa gaaatcactc aaatggccca ccaagtggga gccatcatgg
     5461 tggtggatgg tgctcagtct actcctcata tgaagattga tgttcaggac ttggatgtgg
     5521 acttctttgc cttttcaggt cacaagatgg ctggtccaac tggtatcggt gttctttacg
     5581 gcaaagaaaa gtatctggaa caaatgtcac cagttgaatt tggcggcgaa atgattgatt
     5641 tcgtttatga acaatctgct agttggaagg aattgccttg gaaattcgag gctggaactc
     5701 ctaacatggt tggtgcaatc ggacttgctg ctgcagttga ttatctggaa aagattggta
     5761 tggatgccat tgaagcccat gaacaggaat tgatcgccta tgtctttccg aaattacagg
     5821 cgattgaagg actgaccatt tatggttcac aggacttggc tcaacgttca ggtgtcattg
     5881 cttttaacct aggcgacctt catcctcacg accttgcaac ggctttggat tatgaaggtg
     5941 tggcagttcg tgcgggtcac cactgtgcgc aacccttgct ccagtatttg gatgttccag
     6001 caacagctcg tgcaagtttt tatatctaca ataccaaggc agattgcgac aagctagtcg
     6061 atgccttaca aaagacaaag gagtttttca atggcacttt ctaaactaga tagcctttat
     6121 atggcagtgg tagcagacca ttcgaaaaat ccacaccacc aagggaagtt ggaagatgct
     6181 gagcaaatca gtctcaacaa tccgacctgt ggcgatgtta tcaacctctc tgtcaagttt
     6241 aatgcagaag accgtttgga agatatcgct tttctaaact caggttgtac catctcaact
     6301 gcctctgcaa gcatgatgac agaggcagtt ttaggcaaga ccaagcaaga aattctagaa
     6361 cttgcaacca tcttttctga aatggttcaa ggacaaaaag atgacagaca agatagtctt
     6421 ggagatgcag ccttcttgtc aggtgttgct aaatttcctc aacgaatcaa gtgtgcgacc
     6481 ctagcttgga acgccctgaa gaaaacaatt gaaaatcaag aaaaacagta aggcaagttt
     6541 cttttgtctt atgaatcagt agaaatgaag aatgaaagaa aggatattat ggctgaagaa
     6601 agagtagaac caaaaccaat tgatcttggt gaatataaat ttggtttcca tgatgatgta
     6661 gagcctgtcc tatcgacagg aaaaggattg aatgaagatg tcattcgtga actatcagct
     6721 gccaagggag aacctgagtg gatgttagag ttccgtttga agtcttatga aacctttaaa
     6781 aaaatgccca tgcaaacttg gggagcagac ttgtcagaga ttgactttga tgacttgatc
     6841 tactaccaaa aaccatctga taaaccagct cgttcatggg atgaggttcc tgaaaaaatt
     6901 aaagaaacct ttgagcgtat cgggattcct gaagctgagc gtgcttatct agccggtgcc
     6961 tctgcccagt acgagtcaga agtggtttac cacaacatga aggaagaatt tgagaagtta
     7021 ggtattatct ttacagatac ggattctgcc ctcaaggaat acccagactt gtttaaacaa
     7081 tactttgcta agttggtacc gccaacagat aacaaattgg ctgcccttaa ctcagcagta
     7141 tggtctggtg gaacctttat ctacgtacca aaaggggtca aggtagatat tccacttcaa
     7201 acttacttcc gtatcaacaa cgagaataca ggtcagtttg aacgtacctt gattattgtt
     7261 gatgagggag caagtgtcca ctacgttgaa gggtgtacag cgccaacata ttcaagcaac
     7321 agcttgcacg ctgccatcgt agaaatcttt gccttggatg gtgcttatat gcgttataca
     7381 accatccaaa actggtctga taacgtttat aacttggtaa caaagcgtgc taaagctcaa
     7441 aaggatgcca ctgttgagtg gattgatggt aacttgggtg ccaaaacaac catgaaatac
     7501 ccatctgttt accttgatgg agaaggggcg cgtgggacta tgctttcgat tgcctttgct
     7561 aatgtagggc aacaccaaga tacgggtgct aagatgatcc acaatgctcc acatactagc
     7621 tcatctatcg tgtctaaatc catcgctaaa ggtggaggta aggttgatta ccgtggtcaa
     7681 gtaaccttta acaagaactc taagaaatct gtttctcaca ttgagtgtga taccattatc
     7741 atggatgact tgtcagcatc agataccatt ccgtttaatg aaatccacaa ctcgaaagtt
     7801 gctttggaac acgaagcaaa ggtttctaag atttcagaag agcaactcta ttacctcatg
     7861 agccgtggat tgtcagaatc tgaggcaact gagatgattg ttatgggatt tgtagagccc
     7921 tttacgaaag aacttccaat ggaatacgca gttgagctga accgcttgat tagctatgaa
     7981 atggaagggt cagttgggta aaatttgatt ttatactctt cgaaaatctc ttcaaaccac
     8041 gtcagcatcg ccttaccgta tgtatggtta ctgacttcgt cagtttcatc tacaacctca
     8101 aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gttctttgat tttgagtatt
     8161 agatttactc aaaatcaagg attttgaaga tgaacttgta tcaaaaaatc gcggtttaaa
     8221 atcgcgattt tttataattt ctcgttaaca aagcggacaa actgattcca ccaaactttt
     8281 aagaaaaagg ctttttcaat tttcttgtct gctaccattt cgaaactagg gcgctctgtg
     8341 gtgatgtaac cttgaccaat caagtccttg tcttcataag tcaaatgggc aaccactgtt
     8401 ccagcttcaa gtggtgctgg gattgctttg gaatcaggtg tgaattgaac agattgggaa
     8461 gattgattcc caacacgttc gattagatag atatcctctg gagccactgc agttactgta
     8521 tcttcttttc catcttgtac aggggctttg ctatcttgat aggcatcgcc ttgttgaacg
     8581 attttgcgaa gtgtaaatgt agaagaaata taatccatta gggaagatgt agctgtaaat
     8641 cgagcgtaag gattattgtc ttgatgatct gcatttaaaa caactgtgat gactctcatg
     8701 cctttttcga cagtagtacc aacaaaagac tctccagcct tatctgttgt tcctgttttt
     8761 agcccatcaa aaccaccacg gtaagcaggc atactttcta acatgtagtt ggttgaagtg
     8821 attgtcattc cagcaaaagt agaagaaggt tttttggtga tttccaagac ttgtgggtat
     8881 tttttgatga ggttgcgagc aacaatagcg acatcataag cactaagctt attttcctca
     8941 tcttttttag aacctgggta aatgttatcc cttagagttt cattgttaag acctgtcgta
     9001 ttgacaacag tggcatcctg aattccccat tccaagagtt ttgcccgcat catatcgacg
     9061 aaatcttttt ctgagccagc aattttctca gctagggcaa tagcggcgct gttggcacta
     9121 gataccagag ttgcttcaag caactcttcg acagtataat tacgggcctc cataggaata
     9181 ttactggctt cagaatttgt cgtcaattga taaggataat cagaaatatc tacaggagtg
     9241 gagagggtaa tacttccgtt ttccaaagct tcatagacca gataaacagt aatcaatttt
     9301 gttatggaag caatttcgac aggttgcgtt gcatccttct catagagaat tttaccagta
     9361 tttgcctcaa cagcaatcgc atgtttagcg gcaatggtaa aatcttgagc aacagcagta
     9421 gaagcacccc ctaaaagaga gatagttaat aaagttaaaa atattttttt catagtagtc
     9481 ttattctatc ataaagaaaa aaaatattct tgctttaata attcatctgt taagcttttt
     9541 gaaaatatgg taaaataaag tgagggaggt aactcatgtt tcgtagaaat aaattatttt
     9601 tttggaccac agaaatttta ctcttaacca tcatctttta cctatggaga cagatggggt
     9661 ctttgattaa cccttttgtt agagtgctta atacaattat gattccattt ttattagggg
     9721 gctttcttta ttatttgaca aaccctattg ttactttctt aaataaagtc tgtaaactca
     9781 atcgtttgct tggtatttta attaccttgt gtactttggt ctggggaatg gtcataggtg
     9841 ttgtctatct cttacctatt ttgattaatc agttatctag tttgattata tctagtcaaa
     9901 ctatttatag tcgagtacaa gacttaatca tagacttatc taattatcct gcgctccaga
     9961 atttggatgt agaagctaca attcagcagt taaacttatc ctatgttgat attcttcaaa
    10021 atatcctaaa tagcgtatca aatagtgtgg ggagcgtctt gtcagctctt atcagtactg
    10081 ttttgatttt gattatgact ccagtttttt tggtttattt cttattagat ggacataaat
    10141 tcttgcccat gcttgaaaga acaattctaa agagggatcg cttgcatatt gcaggcttat
    10201 taaagaattt aaatgcgacg attgctcgct atattagtgg agtttcgatt gacgcaatca
    10261 ttataggttg tttggcttat attggctata gtattattgg tttaaaatat gctttagttt
    10321 ttgccatttt ttctggtgta gccaatttaa ttccttatgt gggaccaagt attggtttga
    10381 ttcctatgat catcgcaaat atattcactg atccccatag actgctgatt gcagtgattt
    10441 atatgcttgt tgttcagcag gtagatggca atatcttata tcctcgaatc gtaggaagtg
    10501 ttatgaaggt tcatccaatc acgattttag ttttactttt gttgtcaagc aatatctatg
    10561 gtgtagttgg aatgattgtc gcagtgccaa cctattctat cttgaaagaa atttctaagt
    10621 tcttatcccg tttgtatgaa aatcataaaa taatgaaaga acgagaaaga gaattagcta
    10681 agtaaaagtc aggagaaccc tgatttttct ttactggaag tggcctttag attagaagac
    10741 tgaaaataag ttaaagtctt aaactaattt tcacagctaa gaatagtaga agttaatctg
    10801 ataaaaatcg aaaaaaccag tggaattccg tgtcagggta agttccactg gttttcatag
    10861 tctattaaag ttcgaatgaa acctatttat agtatattga aactagaata gtacacctct
    10921 aattctaaaa cattgttaga aatcgatttg actgtcctga tctattcgtc ctattcttat
    10981 ttcattttac tatattttgg tgcaataagt gaaaagtagt ccgaataata taaggattaa
    11041 ttttatagtt tttaaactca aatgaattaa aataaagaga gtacgaaaat tctcatctga
    11101 aagtatttta gaataattct cttcgtgaat ttcttcaaaa cagatagctt catcttaggt
    11161 atgtgttaat tggatttcgt aagctctatt tacaatcgta aagttatgca ctgagaaagt
    11221 tgtagttagt cttccagttt gctaaatttc tcgaatagta tcttttttag gtatgtgatt
    11281 tctttttgca tttttgagtt agataaggta taatggtttt attgtctttt ggggtcgtta
    11341 cggattcgac aggcattatg aggcatattt tgcgactcgt gtggcgacgt aaacgctcag
    11401 ttaaatataa ctgcaaaaaa taacacttct tacgctctag ctgcctaaaa accagcaggc
    11461 gtgacccgat ttggattgct cgtgttcaat gacaggtctt attattagcg agatacgatt
    11521 aagccttgtc tagcggcttg ataagagatt gatagactcg cagtttctag gcttgagtta
    11581 tgtgtcgagg ggctgttaaa ataatacata acctatggtt gtagacaaat atgttggcag
    11641 gtgtttggac gtgggttcga ctcccaccgg ctccattatt cctttgcatt cttttgcatt
    11701 ccttggtaaa acgttgttaa atcaacgttt tttattttta tctttggtat tcctttgcat
    11761 tcttttgcta aaaagggagt cacaaacaga ccctatttta aaaaaggata caacatttgt
    11821 tgcatcctaa aaataatctt ttttcgacgg aagatatggg attcgaaccc acgcacgcta
    11881 ttacacgcct accgcgtttc caacacggcc tcttaagcct cttgagtaat cttccaatac
    11941 ttactcaaat agtctaccat aaaggctctt atcttgcaat aaaaattcta gaaataagaa
    12001 aaatgataga ttttgaaaga aaatgataaa aaatgcttga cttcaaaata aagtatggta
    12061 gaatgaatag tgtaaacgat aacaggaggt gattcagtgt taaaaacaga acgtaaacaa
    12121 ctgattttag aggagttaaa tcaacatcat gtagtttctc tagaaaaatt agttagtttg
    12181 ctagaaactt cagaatcaac ggttcgaaga gacttggatg agttggaagc ggaaaacaag
    12241 cttcgtcgtg tgcatggtgg agcagaactc ccccactcct tacaggaaga agaaaccatt
    12301 caagaaaaat ctgtcaaaaa ccttcaagaa aagaagttgc tggctcagaa agcagcctct
    12361 ctcattaaag aaaaagatgt catctttatc gatgctggaa caacaactgc ttttttgatt
    12421 catgaattgg tcaataagaa tgttacagtt gtgaccaact ccattcacca tgccgctcag
    12481 ttggttgaaa agcagattcc aactgtcatg gttggaggaa acgtcaagac ggcgacagat
    12541 gctagtatcg gtggcgttgc tcttaaccag attaaccaat tgcactttga ccgtgccttt
    12601 atcggaatga atggtgttga cgatggctat tatacgactc ctgatatgga ggagggagct
    12661 gtgaaaagag ctattttgga gaatgccaag cagacctacg tcttggtgga ttcgtcaaaa
    12721 attggacaaa cttgctttgc caaggtagca ccactcaaac gcgctatcgt tatcactagt
    12781 caagggcatg agctcttgca gggtattaag gagaaaacgg aggtaataga agtatgattt
    12841 atacagtcac actcaatcca tccattgact atatcgttcg tttggaccaa gtcaaagttg
    12901 gtagtgtaaa tcgtatggac agtgatgata agtttgctgg tgggaaagga atcaatgtca
    12961 gccgtgtctt gaaacgtttg aatataccaa atacagcgac gggatttatc ggtggcttta
    13021 ctggtaaatt tatcacagat actttagcag aggaagaaat cgagacacgt tttgtccagg
    13081 tggcagaaga tactcgtatc aatgttaaaa tcaaagcaga ccaagaaaca gaaatcaacg
    13141 gaacgggtcc aactgttgaa ccggttcagc tagaagaatt gaaagctatt ttatctagtc
    13201 tgacagcaga agatacagtt gtctttgcag gttcaagtgc taaaaatcta ggcaatgtta
    13261 tctataagga tttgatttcc ttgacgcgcc agactggtgc gcaagtggtc tgtgactttg
    13321 aaggacagac cttaattgat agtttggact accagcctct tcttgtaaaa ccaaacaatc
    13381 atgaacttgg agcgattttt ggggttaaac tcgaaagttt agatgaaatt gagaaatacg
    13441 ctcgtgagtt actggctaag ggtgctcaaa atgttattat ctctatggct ggtgatggcg
    13501 cccttcttgt cacatctgag ggagcttact tcgctaaacc aatcaaagga acagtcaaaa
    13561 attcagttgg agctggtgat tctatggttg ctggattcac aggtgaattt gtcaaatcaa
    13621 aagacgcagt agaagccttc aaatggggag tggcttgcgg aacggcaact accttctcag
    13681 atgacttggc aacggcggaa tttattaaag aaacatatgg aaaagttgag gtagaaaaaa
    13741 gatgaaaatt caagacctat tgagaaaaga tgtcatgttg ctagatttgc aggcaactga
    13801 aaaaacagct gtcatcgacg agatgattaa aaatttgaca gagcacggtt atgtaacaga
    13861 ttttgaaaca tttaaagaag gaattttggc gcgtgaagct ttgacttcta ctggtttggg
    13921 tgatggaatc gcaatgcctc acagcaaaaa cgctgctgtc aaagaagcga cagttctatt
    13981 tgctaagtca aataagggtg ttgactacga gagcttggat ggacaagcaa ctgacctctt
    14041 cttcatgatt gcagctccag aaggtgccaa tgatactcac ttggcagcct tggcagaatt
    14101 gtctcaatac ttgatgaaag acggttttgc agacaaactt cgtcaagcaa catctgcaga
    14161 ccaagttatc gaactttttg accaagcttc agaaaaaact gaggaacttg ttcaagcacc
    14221 tgctaatgac tctggtgact ttatcgtagc tgttacagct tgtacaacag gtattgccca
    14281 cacttacatg gcccaagaag cccttcaaaa agtagctgct gaaatggggg ttggtatcaa
    14341 ggtcgaaacc aacggtgcta gcggtgttgg aaatcaacta actgcagaag atatccgtaa
    14401 ggctaaagct attatcattg cagcagacaa ggccgttgaa atggatcgat ttgatggaaa
    14461 accattgatc aatcgtccag ttgctgacgg tatccgtaag acagaagagt taattaactt
    14521 ggctctttca ggagatactg aagtctaccg tgccgctaat ggtgcaaaag ctgcaacagc
    14581 ctctaacgaa aaacaaagcc ttggtggtgc cttctacaaa cacttgatga gtggtgtatc
    14641 tcaaatgtta ccattcgtta tcggtggtgg tatcatgatt gcccttgcct tcttgattga
    14701 cggtgctttg ggtgttccaa atgaaaacct tggcaatctt ggttcttacc atgagttagc
    14761 ttctatgttc atgaaaattg gtggagctgc ctttggtttg atgctgccag tctttgcggg
    14821 ttatgttgcc tactctattg ctgaaaaacc aggtttggta gcaggtttcg tggctggtgc
    14881 tattgccaaa gaaggttttg cctttggtaa aattccttat gccgcaggtg gtgaagcaac
    14941 ttcaactctt gcaggtgtct catctggttt cctaggtgcc cttgttggtg gatttatcgc
    15001 aggtgccttg gttcttgcca tcaagaaata cgttaaagtt cctcgttcac tcgaaggtgc
    15061 taaatcaatc cttctattgc cacttcttgg aacaatcttg acaggatttg ttatgctagc
    15121 tgtaaatatc ccaatggctg caatcaatac tgctatgaat gacttcctag gcggtcttgg
    15181 aggaggttca gctgtccttc ttggtatcgt ccttggtgga atgatggctg ttgacatggg
    15241 tggaccagtt aataaagcag cttatgtctt tggtacaggt acgcttgcag caactgtttc
    15301 ttcaggtggt tctgtagcca tggcagcagt tatggctgga ggaatggtgc caccacttgc
    15361 aatctttgtc gcaactcttc ttttcaaaga taaatttact aaggaagaac gtaactctgg
    15421 tttgacaaac atcatcatgg gcttgtcatt tatcactgag ggagcgattc catttggtgc
    15481 cgctgaccca gctcgtgcga ttccaagctt catccttggt tcagcagtag caggtggact
    15541 cgttggtctt actggtatca aactcatggc gccacacgga ggaatcttcg ttatcgccct
    15601 tacttcaaat gctctccttt acctcgtttc tgtcttggta ggagcaatcg taagtggtgt
    15661 ggtttatggt tacctacgca aaccacaagc ataaaaaata gaaaaatgaa aagattggac
    15721 cgtttggtgc agtctttttc tcttcccgaa atgcctgtga aatatggtat aatagaagaa
    15781 tggcaaacaa gaatacaagt acaacaagac ggagaccgtc taaagcagaa ctggaaagaa
    15841 aagaagcgat tcaacgaatg ttgatttcgt taggaattgc gattttattg attttcgcag
    15901 ccttcaaatt aggggctgca ggtataaccc tttataattt aattcgcttg ctagtgggta
    15961 gcctagctta tctggcgata ttcggcctat taatctatct cttctttttc aagtggatac
    16021 gaaaacagga aggactctta tctggctttt tcaccatatt tgctggctta ctcttgattt
    16081 ttgaggccta cttggtttgg aaatatggtt tggacaagtc cgttctaaaa gggaccatgg
    16141 ctcaggttgt gacagatctg actggttttc gaacgactag ctttgctgga gggggcttga
    16201 tcggggtcgc tctttatatt ccaacagcct ttctcttttc aaatatcgga acttacttta
    16261 ttggttctat cttgatttta gtgggttctc tcctagtcag cccttggtct gtttacgata
    16321 ttgctgaatt tttcagtaga ggctttgcca aatggtggga agggcacgag cgtcgaaaag
    16381 aggaacgctt tgtcaaacaa gaagaaaaag ctcgccaaaa ggctgagaaa gaggctagat
    16441 tagaacaaga agagactgaa aaagccttac tcgatttgcc tcctgttgat atggaaacgg
    16501 gtgaaattct gacagaggaa gctgttcaaa atcttccacc tattccagaa gaaaagtggg
    16561 tggaaccaga aatcatcctg cctcaagctg aacttaaatt ccctgaacag gaagatgact
    16621 cagatgacga agatgttcag gtcgattttt cagccaaaga agcccttgaa tacaaacttc
    16681 caagcttaca actctttgca ccagataaac caaaagatca gtctaaagag aagaaaattg
    16741 tcagagaaaa tatcaaaatc ttagaagcaa cctttgctag ctttggtatt aaggtaacag
    16801 ttgaacgggc cgaaattggg ccatcagtga ccaagtatga agtcaagccg gctgttggtg
    16861 taagggtcaa ccgcatttcc aatctatcag atgacctcgc tctagccttg gctgccaaag
    16921 atgtccggat tgaagcacca atccctggga aatccctaat cggaattgaa gtgcccaact
    16981 ccgatattgc cactgtatct ttccgagaac tatgggaaca atcgcaaacg aaagcagaaa
    17041 atttcttgga aattccttta gggaaggctg ttaatggaac cgcaagagct tttgaccttt
    17101 ctaaaatgcc ccacttgcta gttgcaggtt caacgggttc agggaagtca gtagcagtta
    17161 acggcattat tgctagcatt ctcatgaagg cgagaccaga tcaagttaaa tttatgatgg
    17221 tcgatcccaa gatggttgag ttatctgttt acaatgatat tccccacctc ttgattccag
    17281 tcgtgaccaa tccacgcaaa gccagcaagg ctctgcaaaa ggttgtggat gaaatggaaa
    17341 accgttatga actctttgcc aaggtgggag ttcggaatat tgcaggtttt aatgccaagg
    17401 tagaagagtt caattcccag tctgagtaca agcaaattcc gctaccattc attgtcgtga
    17461 ttgtggatga gttggctgac ctcatgatgg tggccagcaa ggaagtggaa gatgctatca
    17521 tccgtcttgg gcagaaggcg cgtgctgcag gtatccacat gattcttgca actcagcgtc
    17581 catctgttga tgtcatctct ggtttgatta aggccaatgt tccatctcgt gtagcatttg
    17641 cggtttcatc aggaacagac tcccgtacga ttttggatga aaatggagca gaaaaacttc
    17701 ttggtcgagg agacatgctc tttaaaccaa ttgatgaaaa tcatccagtt cgtctccaag
    17761 gctcctttat ctcggatgac gatgttgagc gcattgtgaa cttcatcaag actcaggcag
    17821 atgcagacta cgatgagagt tttgatccag gtgaggtttc tgaaaatgaa ggagaatttt
    17881 cggatggaga tgctggtggt gatccgcttt ttgaagaagc taagtctttg gttatcgaaa
    17941 cacagaaagc cagtgcatcc atgattcagc gtcgtttgtc agttggattt aaccgtgcga
    18001 cccgtctcat ggaagagctt gagatggcag gtgtcattgg tccagctgaa ggtaccaagc
    18061 caagaaaagt attgcagcaa taaaaaatag cttctttcca aggttggaag gaagctattt
    18121 ttctggttat tgattacttt tattttctga agttggagta ttgggctgtt tttcattttc
    18181 agtggcaggt ttacttgtag caggtgtagt agagtcctga gttgctgttt tctgctcttc
    18241 ttttttctct tccttgacgc tagattttgg cgtttcttct tgttgtgttt tttcttgaga
    18301 agtgttattt tccttatttg gagtagtatt ttcctgaggg gattcttttt gaatttcttt
    18361 gacaaaggtt gtcgtctggc ttgtcgtagg ttcttttttg gtatttttat tattatccaa
    18421 ggcattcatg atcgtgatag tcgcagtaat caagccgagg atactaccga tagtagtaat
    18481 ggttttttga aaaacagtaa agcctttttt gatatgttct gttttcggtt ttgaagttct
    18541 acgataatta gacatgcatt ctctcctttg attatgactt attatactct gtttctttaa
    18601 aaaaatctta aaaaaagaga aattgccctt tcttgtcgca agctctgttt catgatacaa
    18661 tagagggagt gattttagaa agcgtgagaa acatgattta ctttgataat tcagcgacga
    18721 ccaagcctta tcctgaagcc cttgaaacct atatgcaggt cgcttcaaaa attttaggaa
    18781 acccatctag tctccatcgt ttgggagacc aagcaacacg aatattagat gcttctcgcc
    18841 aacagattgc agatttaatc ggtaagaaaa gcgatgaaat cttctttacc tctggtggaa
    18901 cagaagggga taactgggtt atcaagggtg tggcctttga aaaagctcag tttggcaagc
    18961 acatcattgt ttcagccatt gaacatctag cagtcaaaga gtcagccctc tggttgaaaa
    19021 gtcaaggatt tgaagtggat tttgctcccg ttgataagaa aggctttgtc gatgttgagg
    19081 cgttagcaga tttgatacgt cctgatacga ccctcgtttc catcgtggca gttaacaatg
    19141 aaattggctc tgttcagccc attgaggcta tttcagaatt gttggcagat cagccgacta
    19201 tttctttcca cgttgatgcg gttcaggcgc ttgccaagat tccgactgaa aagtatctga
    19261 cagaacgggt ggattgcgcg actttctctg gtcacaagtt ccacggagtt cgtggtgttg
    19321 gttttgtcta tatcaagtct ggcaagaaga ttacgcctct tttaacaggt ggtggtcagg
    19381 agcgcgacta tcgttcgaca actgaaaatg tggcagggat tgcagcgaca gccaaggctc
    19441 tgcgtttgtc tatggaaaaa ctggatatct ttaggagtaa gacagggcag atgaaggcag
    19501 tgattcgcca agctctttta gattatccag atatatttat cttttcagct gaggaagact
    19561 ttgcccctca tatcctgact tttggaatca agggtgttcg tggtgaagtc atcgttcacg
    19621 cctttgaaga ctatgatatt ttcatctcaa caacctctgc ttgttcgtcc aaggctggga
    19681 aacctgcagg taccttgatt gccatgggag tggataagga taaggcccag tcagctgtgc
    19741 gtcttagtct agaccttgaa aatgatatga gtcaggtcga gcagtttttg accaagttaa
    19801 aattgattta caatcaaact agaaaagtaa gataggagca ttcatgcagt attcagaaat
    19861 tatgattcgc tacggtgagc tgtcaaccaa gggtaaaaac cgtatgcgtt tcatcaataa
    19921 acttcgcaat aatatttcag acgttttgtc tatctatccc caagttaagg taagggcaga
    19981 tcgcgaccgt gcccacgctc acctcaatgg agcagattac acagcagtag cagaatcgct
    20041 caaacaagta tttggaattc agaatttttc tcctgtttat aaggttgaaa aatctgtaga
    20101 agttttgaag tcttctgtcc aagagattat gcgggacatc tacaaggaag gtatgacctt
    20161 taagatttct agcaagcgta gcgaccacaa ctttgaactt gatagtcgtg aactcaacca
    20221 aacacttgga ggggctgtat tcgaagccat tccaaatgtg caagttcaaa tgaaaagtcc
    20281 tgacatcaat cttcaggtgg agattcgtga agaagcagcc tatctttctt atgaaaccat
    20341 tcgtggggct ggtggtttgc cagttggaac ttcaggtaaa gggatgctca tgttgtcagg
    20401 agggattgac tcacctgtag caggttatct tgctcttaag cgtggggtgg atatcgaggc
    20461 agttcacttt gctagtccac catatactag tcctggtgcc ctcaagaaag cgcaggactt
    20521 gacccgtaaa ttgaccaagt ttggcggaaa tatccagttt attgaggtgc ctttcacaga
    20581 gattcaagag gaaatcaaag ccaaagcgcc agaagcttat ttgatgactc taactcgtcg
    20641 ctttatgatg cggattactg accgtattcg tgaggtacga aatggtttgg ttatcatcaa
    20701 tggggaaagt ctaggtcaag tagccagcca aacccttgaa agtatgaagg ctatcaatgc
    20761 tgttaccaac actcccatca ttcgtcctgt ggttaccatg gacaagttgg aaatcattga
    20821 catcgcccag gaaatcgata cctttgacat ttcaatccaa ccgtttgaag actgttgtac
    20881 catttttgca ccagatcgtc caaaaacaaa tcctaaaatt aagaatgcgg agcagtacga
    20941 agcgcgtatg gatgttgaag gcttggttga gcgagcagtg gctggaatca tgattactga
    21001 aatcacacct caagccgaaa aagatgaagt tgatgacttg attgacaatc tgctctaatt
    21061 cagaaaatcc aaaagaatag cgaaaatcag taaaaaaagt tagttttttc tctaaaaaca
    21121 ggtaaaaaac taactttttt ctatttttat gatataatga tataaaattt tgaatataga
    21181 gagttttctg acaatgaatc aatcctactt ttatctaaaa atgaaagaac acaaactcaa
    21241 ggttccttat acaggtaagg agcgccgtgt acgtattctt cttcctaaag attatgagaa
    21301 agatacagac cgttcctatc ctgttgtata ctttcatgac gggcaaaatg ttttttatag
    21361 caaagagtct ttcattggac attcatggaa gattatccca gctatcaaac gaaattcgga
    21421 tatcagtcgc atgattgtcg ttgctattga caatgatggt atggggcgga tgaatgagta
    21481 tgcggcttgg aagttccaaa aatctcctat cccagggcag cagtttggtg gtaagggtgt
    21541 ggagtatgct gagtttgtca tggaggtggt caagcctttt atcgatgaga cctatcgtac
    21601 aaaagcagac tgccagcata cggctatgat tggttcctca ctaggaggca atattaccca
    21661 gtttatcggt ttggaatacc aagaccaaat tggttgcttg ggcgtttttt catctgcaaa
    21721 ctggctccac caagaagcct ttaaccgcta tatcgagtgc cagaaactat cgcctgacca
    21781 gcgcatcttc atctatgtag gaacagaaga agcagatgat acagacaaga ccttgatgga
    21841 tggcaatatc aaacaagcct acatcgactc gtcgctttgc tattaccatg atttgatagc
    21901 agggggagta catctggata atcttgtgct aaaagttcag tctggtgcca tccatagtga
    21961 aatcccttgg tcagaaaatt taccagattg tctgagattt tttgcagaaa aatggtaagt
    22021 taagaaagaa aaaaacgaaa tgcatattga atatcttagc cactggagtg gtcatcttaa
    22081 ccgtgaaatg taccttaacc gttatggaca tgctgggatt ccagttgtgg tctttgcttc
    22141 atcaggtggt agtcacaacg aatactatga ttttggcatg attgatgcct gcacttcctt
    22201 tatcgaggaa ggccgtgtcc agttctttac cctatctagt gtggatggtg agagctggtt
    22261 ggctacttgg aaaaatgctc atgaccaagc ggaaatgcac cgttcctacg aacgttatgt
    22321 gattgaggag gccattcctt ttatcaagca caagacaggt tggtttgatg gcatgatgac
    22381 gacaggttgc tctatgggag cctatcatgc actcaatttc ttcctccagc atccagatgt
    22441 ctttaccaaa gtgattgctc tcagtggtgt ttacgacgca cgtttctttg tcggtgatta
    22501 ctacaacgat gatgctattt accaaaactc gccagtagat tatatttgga accaaaacga
    22561 cggctggttt attgaccgtt accgtcaggc agagattgtg ctgtgtacgg ggcttggagc
    22621 ctgggaacaa gatggtttgc catcctttta caagctcaaa gaagcctttg acaagaaaca
    22681 aattccagcc tggtttgctg aatggggaca tgatgtcgcc catgactggg aatggtggcg
    22741 taaacaaatg ccttatttcc tcggtaatct ctatttataa aaggagttac ctatgaatta
    22801 ccttgttatt tctccctact atccacaaaa ctttcaacag tttaccatcg aactagctaa
    22861 taaaggcatc acagtcttgg gaattggtca agagtcttac gagcaattgg atgagccctt
    22921 gcgcaatagc ttgatcgagt attttcgtgt tgataatctt gagaacatag atgaagtcaa
    22981 acgtgcagtt gcttttctct tttataaaca tggtccaatt gaccgcatcg agtctcacaa
    23041 tgaatactgg cttgagctag acgcaacact cagagaataa ttcaatgttt ttggtgccaa
    23101 accagaggat ctcaaaaaga cgaaatataa gtctgaaatg aagaaacttt tcaaaaaagc
    23161 aggtgttcct gtggtacctg gagctgttat caagacggaa gcagatgttg atcaagcagt
    23221 gaaggaaatc ggtcttccaa tgattgccaa acctgataat ggagtgggag cagccgcaac
    23281 ctttaaactt gagacagaag acgatatcaa tcacttcaag caagaatggg accattcaac
    23341 cctttatttc tttgaaaaat ttgtcacttc cagcgaaatc tgtacctttg acgggctcgt
    23401 ggacaaggat ggaaagattg tcttctcaac aacctttgac tacgcctata caccacttga
    23461 cctcatgatt tataagatgg acaattctta ttatgtgctc aaggatatgg atcctaaact
    23521 gcgcaagtat ggggaagcaa ttgtcaaaga atttggtatg aaagaacggt ttttccatat
    23581 tgagttcttc cgtgaggggg acgattatat taccatcgag tacaataacc gccctgcagg
    23641 tggttttacc attgatgttt ataactttgc tcattccttg aacctttatc gtggctatgc
    23701 agctattgtc gcaggagagg agttcccagc gtcagacttt gaaactcagt attgtttggc
    23761 tacttctcgc cgtgcaaatg ctcactatgt ttattcagaa gaggatttgc ttgccaaata
    23821 tagccagcag ttcaaggtta aaaaagtcat gccagctgcc ttcgcggaac ttcaaggaga
    23881 ttacctgtat atgctgacca ctccgagtcg acaagaaatg gagcagatga ttgcagattt
    23941 cggacaacgt caagaataag aactatcgga ttaaggaaat taactccctt aatgcttttg
    24001 ttttgtctga taaaaaataa gagcatccca acaaggtagc tatcataaaa cttgttcgat
    24061 aactatttga agcaggatta ggtggttaga aattgaattt taatatttca attgagtcat
    24121 agtattgtgt tttcgtatcc ttaaatcagc taaaaggatc catgacgaca cctatacgat
    24181 atagttttca agataccaaa caagtctatt aatactcaat gaaaatcaaa gagcaaacta
    24241 ggaagctagc cgcaggtttc tcaaaacact gttttgaggt tgtggataga actgacagag
    24301 tcagtatcat atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttcgaagag
    24361 tataaaatat tcaggtgacg catagatata gttaattgaa gctttgtttg aaatctgata
    24421 aaataatgat attactaagt tttaaaaact aaagaaaagg gaagatatga ttacaggcga
    24481 attaaaaaat aaaatcgatc agttgtggga aattctttgg acagaaggaa atgcaaatcc
    24541 tttaacaaat attgaacagt tgacttatct cttatttatg aaagatttgg atactgtcga
    24601 gcttggacgt gaaagtgatg ctgaatttct agggattcct tatgagggag tttttccaaa
    24661 agataaacct gaataccgtt ggtcaacttt taaaaacata ggagatgctc aggaagttta
    24721 tcgtttaatg actcaggaga tttttccgtt tattaaaaat ctcaaggggg atacagatga
    24781 tacagccttt tcacgatata tgcgagaagc tatttttcaa ataaataaac ctgctacgct
    24841 tcaaaaggca atttctatct tagatgtttt tccaactagg ggattagatg tagattttga
    24901 taatgacaaa caaagtatta ctgatatcgg agatatctat gaatatctgt tatcaaaatt
    24961 gtcgaccgca ggtaaaaatg gacagttccg tacacctcgt cacatcatcg atatgatggt
    25021 tgagttgatg caaccaacta tcaaagatat catctcagat cccgctatgg gttctgctgg
    25081 cttcttagta tccgctagcc gttacttaaa gcgtaagaaa gatgaatggg aaaccaatac
    25141 agataatatc aatcattttc ataatcagat gtttcatgga aatgatacgg atacgactat
    25201 gttgagactt ggggcgatga acatgatgct acatggagta gaaaacccac aaatcagtta
    25261 ccttgactcg ctgtctcaag ataatgaaga agccgataaa tatactttgg ttttaacaaa
    25321 tcctcctttt aagggctcac ttgactacaa ttcaacctat aatgaccttc ttgcaaccgt
    25381 aaaaaccaaa aaacagaatt actctttctt tctcttttct tgcgaacttt aaaaccaggt
    25441 ggacgagcag cagttatcgt acctgatggt gtcctttttg gttcgtctaa agctcataaa
    25501 ggaattcgtc aggaaattgt agagaaccat aagattaatg ctataatctc aatgcctagt
    25561 ggtgttttca agccttatgc tggagtttca actgccattc tcatctttac aaaaactggc
    25621 aatggtggta ccgacaaggt ctggttttac gatatgaaag cggatggttt gagtttggat
    25681 gataaatgac aaccaattag tgacaatgat attccagata ttatcgaacg ctttcatcat
    25741 cttgaaaaag aagtagaacg tcagagaacg gatcaatctt tctttgttcc agttgctgag
    25801 ataaaggaaa atgattatga tttgtctatc aataaatata aagagattga gtatgaaaaa
    25861 gttgagtatg aaccaacaga agtcatatta aagaaaatca atgatttaga aaaagaaatt
    25921 caagctggct tggctgaatt ggaaaaatta ctcaagtagg gaggtggctg tatgaaaaaa
    25981 gtgaagttgg gggaagtctt atctctaaaa aaaggcaaga aagccactgt acttgctgaa
    26041 caaacaactc taagccaacg ttatattcaa atagatgatt taagaaataa taataattta
    26101 aaattcactg aaagtttaaa tatgactgaa gcactcccag atgatattct gatagcatgg
    26161 gatggagcta atgcaggaac agttggttat ggattatcgg gagctgttgg tagtacaatt
    26221 acggtcttaa aaaagaatga gcgatacaaa gaaaaaatta tatcagatta cttgggagtc
    26281 tttttggaaa gtaaatccag ttttcttatg gaagcttatt acaaatgaga aaacaaaatt
    26341 aaaaattaag agaatttcct ctggaactag tgggagtatg aaaaatattt cgaaatcaca
    26401 attgttacaa attagagttc ccttcccccc actagccctc caaaatgagt tcgcagactt
    26461 tgtagccctg gtcgacaaat cacaattggc aatccaaaaa tctctggaag aacttgaaac
    26521 tttgaagaaa tctctgatgc aggagtattt tggctgatat tctgccattg taattacggt
    26581 aatgatttgt tataatactt caaaggagga aatcagatgg tagtaaaaac aagaaaacaa
    26641 ggaaattcaa tcaccattac gattccaagt gaatttaata ttccaagtgg tgttaaatac
    26701 gaagcgaaat tgttaccaag tggtgagatt atctttactc ctgaagaatt ggggcagcag
    26761 gtttcttatg tatctgatga tgcctttgac ttaaatttag ataaaatatt tgacgaatac
    26821 gacgatgttt tcaaagcttt ggtggaaaaa tgacaatcta tctgacagaa aagcaaattg
    26881 aaaaaataaa ttctttagca attcaacggt attctccaaa tgagaaaatt caaacagtta
    26941 gtccttctgc cttaaatatg attgtgaact taccagaaca atttgtcttt gggaagcctc
    27001 tttatccaac aatttttgat aaagcaacga tactatttgt ccaattgata aagaagcatg
    27061 tttttgctaa tgctaataaa agaactgctt tcttcgtttt ggtcaaattt ttacaattaa
    27121 acggctatcg tttttctgta acggtagaag aagcagtaaa aatgtgtgta accatcgcag
    27181 tagaagcttt aactgatgaa aaaatgacaa gctactccaa atgggtttct gaacattctg
    27241 ttagagaaaa ggtcaaaaag taacctagta tgctggattt gaatgagcac aagaaaataa
    27301 atgaacagac aatattagaa ttctgtaatg cagaaactga tattgtctct ttttattgat
    27361 gaataagaaa gtgagaaatt atggaatcaa aagttacaat tatcatgcaa gaaatgttac
    27421 ctcttttaaa taatgaacaa ttactagcgt tgagagagag tttagaacat catctagtag
    27481 acggaaaaaa gcagcagaag tattcgaata ataacctgtt gcaactattt attaccgcca
    27541 agcaggtaga gggctgtagc tcaaaaacaa ttcgttatta ccagaggacg attgaaaact
    27601 tgtttaatgc tattaaagag tctgtgacac aactcacaac agatgattta aggagttatt
    27661 tagcaaatta ccagtctgaa aaggattgta gtaaggcaaa cttagacaat attaggcgta
    27721 tattgtcttc tttttttgct tggcttgagc aagaggaata tatcattaaa aatcccattc
    27781 gacggataaa gaaaattaag actgagcaaa atgtgaagga aacttatact gatgaacatt
    27841 tggaaattat gcgtgataac tgtgaaaatt tgagagattt ggcaataata gacctactag
    27901 tatcgtgtag gggagcttgt acagttgaat cgttcagata ttgattttga aaacagagag
    27961 tgtgttgtct ttggtaaagg aaagaaggag agaccagtat attttgacgc tcggacgaaa
    28021 attcatttaa gaaattatct taacgacaga aaagatagtc accctgctct ttttgtaacg
    28081 ctagttggaa aagcccagag acttggaatt gctggtgtag agattcgctt aagaaaatta
    28141 ggagacaaac tcggcataca aaaggttcac ccacataagt tcagaagaac tttagcgact
    28201 aaggcaattg ataaaggtat gcctatcgaa caagtccaaa aactgctagg tcatagcaag
    28261 attgacacaa ccctggccta tgccatggtc aatcaaaata atgtcaagca ttcacaccaa
    28321 aaattcatct cttaaaagca aatcccgata ttccgaggag gtggttgcat gaaaaaagtg
    28381 aaattagggc aagtggctac ttttatcaat ggctatgctt ttaaacctca agattggtca
    28441 tctgaaggga aagagattat cagaatacag aatctgacta aaacttcaaa agggataaat
    28501 tattattcgg gtacgattga taaaaaatac attgttgaag ctggtgatat tcttatttcg
    28561 tggtcgggta cattaggggt ttttcagtgg tgtggaagat ccgcagtgtt aaatcagcac
    28621 atttttaaag tggtttttga taagatagat atagataaat cgtattttaa atatgttgtt
    28681 gaaaaaggtt tgcaagatgc tgtaaaacat actcatggtt ccacaatgaa acatttaact
    28741 aaaaaatatt ttgataatat tatggtttca tatacaaatt tgagagagca acaaagaatt
    28801 gcaagtgagc tggatttgtt aagcaagctg attttaagga gacaagaaca acttgaagag
    28861 cttaatctac ttgtaaaatc ccgatttaac gagatgtttg gggaaaataa aatatttgaa
    28921 agcattgata acttatttga tattatagat ggtgataggg gcaaaaatta tcctaaatca
    28981 gatgagttgt ttagtgagga
//
LOCUS       DAVDHZ010000026        27990 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000026 DAVDHZ010000000
VERSION     DAVDHZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.026"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(43..1404)
                     /gene="pdrM"
                     /locus_tag="VUR46_001361"
     CDS             complement(43..1404)
                     /gene="pdrM"
                     /locus_tag="VUR46_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET5456774.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            complement(1415..1675)
                     /locus_tag="VUR46_001362"
     CDS             complement(1415..1675)
                     /locus_tag="VUR46_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456775.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPTSNRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            complement(1689..2957)
                     /locus_tag="VUR46_001363"
     CDS             complement(1689..2957)
                     /locus_tag="VUR46_001363"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET5456776.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQEVLQSAAKDKINVKTVATITKNFNGQDLTDFKALLEVGAVGFSDDGIPLESSKVV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAKEHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAQVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPSKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            complement(2970..3434)
                     /locus_tag="VUR46_001364"
     CDS             complement(2970..3434)
                     /locus_tag="VUR46_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET5456777.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            complement(3444..4097)
                     /locus_tag="VUR46_001365"
     CDS             complement(3444..4097)
                     /locus_tag="VUR46_001365"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET5456778.1"
                     /translation="MEHSSWHALIKEQLPKGYFGKINQFMEQVYAQGTIYPPKEKVFQ
                     ALLTTPLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAVQANGHAGQIWEPFTDAVIQVVNQLDKPVVFILWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANALLKETGQEPIDWLR"
     gene            complement(4143..4592)
                     /locus_tag="VUR46_001366"
     CDS             complement(4143..4592)
                     /locus_tag="VUR46_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456779.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNETVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLNCKKWFR"
     gene            complement(4606..5319)
                     /locus_tag="VUR46_001367"
     CDS             complement(4606..5319)
                     /locus_tag="VUR46_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET5456780.1"
                     /translation="MSYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQGKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIDRDYDLYAATNGITAIQTGRLAQSGLEPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVH
                     SYQDLLDCLDKNILEKITF"
     gene            complement(5767..6141)
                     /locus_tag="VUR46_001368"
     CDS             complement(5767..6141)
                     /locus_tag="VUR46_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HET5456781.1"
                     /translation="MESIGLVIVSHSKNIAEGLVELISEVAKDVPITYVGGTEDGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAKMNLEMVADFSDKSIMINRVPIVEGAYTAAA
                     LLQAGAELSVIQTQLSELEINK"
     gene            complement(6141..6716)
                     /gene="dhaL"
                     /locus_tag="VUR46_001369"
     CDS             complement(6141..6716)
                     /gene="dhaL"
                     /locus_tag="VUR46_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HET5456782.1"
                     /translation="MNAEQALEWMKLFNEKIQEQKDYLSELDTPIGDGDHGGNMARGM
                     AAVMENLEGKQFETSSDVFKVVSMQLLSKVGGASGPLYGSAFMGMSKADSHSKLEEIL
                     QSGLDMIVKREKAVVGEKTMVDVWTPAIAALSDGQLTHELIDKVVNATKDLLATKGRA
                     SYVGERSLGHIDPGSFSSGLLFTAILETGVV"
     gene            complement(6738..7727)
                     /gene="dhaK"
                     /locus_tag="VUR46_001370"
     CDS             complement(6738..7727)
                     /gene="dhaK"
                     /locus_tag="VUR46_001370"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HET5456783.1"
                     /translation="MKKIINKPTQVVDEMLQGLSFMHDDLVERLDGFDVIVRKVEKTG
                     KVGLISGGGSGHEPSHAGFVGDGMLSAAICGAVFTSPTPDQILEAIKAADEGAGVFMV
                     IKNYSGDIMNFEIAQELAEMEGIDVASVVVDDDIAVENSLYTQGRRGVAGTILVHKIL
                     GAAARSGKSLSEMKDLADKLVLEIKTIGLALSGATVPEVGKPGFILEDDEFEYGVGIH
                     GEPGYKKEKMQPSAQLASELVEKLSEGFQLKAGERYGLLINGLGSTPLMEQYVFANDV
                     AKLLHEKGVELSFKKIGNYMTSIDMAGLSLTLIRLANDEWLDALNAPVTTPAW"
     gene            7881..8411
                     /gene="dhaS"
                     /locus_tag="VUR46_001371"
     CDS             7881..8411
                     /gene="dhaS"
                     /locus_tag="VUR46_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000168609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase transcriptional
                     activator DhaS"
                     /protein_id="HET5456784.1"
                     /translation="MASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFY
                     NHFLDKYELLDWIFETDLTEYITNNLDFISGQKLLQELFLYFEQERDFYIQLFDIQGQ
                     NNFYDQFISYCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVKAYVNKKSPV
                     PQPDFLIMTIIGKRPQ"
     gene            8408..9397
                     /gene="dhaQ"
                     /locus_tag="VUR46_001372"
     CDS             8408..9397
                     /gene="dhaQ"
                     /locus_tag="VUR46_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DhaKLM operon coactivator DhaQ"
                     /protein_id="HET5456785.1"
                     /translation="MTFISNHKQKIISSYISATVSSHPELEKHPTLPLVYQKNRNPHQ
                     VPILSGGGSGHEPAHIGYVGEGMLTAAIYGQLFTPPTRTEILESIRFLNNGHGVFIIV
                     KNFEADIKEFSWAINTARQEGIKVGYSLAHDDISIEPHNRFQIRGRGLAGTILLHKVL
                     GYAAQNGADIEQLTDLGHELAPEIATIGFATKSASLPQATLPLFNLEEGNISYGIGIH
                     GEEGYRIVPFQSSEILANEIISKLRLHYHWKKGDQFILLVNNLGTTSNLEMGIFINDI
                     LQLLEIEGVTITFIKSGTFMTSLDMAGISVTLCPVKNKQWLKALNAPTTAFAW"
     gene            complement(9459..10031)
                     /locus_tag="VUR46_001373"
     CDS             complement(9459..10031)
                     /locus_tag="VUR46_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET5456786.1"
                     /translation="MPRPKTKEELVLASKENYDKLNRFISQLSEDELQTPFDFSKDQK
                     KKEAHWKRDKNLRDVLIHLYEWQQLLLTWVHSNQKGHERPFLPEPYNWKTYGKMNVTI
                     WKKHQKTSLEEATRLLEQSHREVLELMEGFSNDELFAKGIYKWTGGTSLGSYFVSSTS
                     SHYDWALKKIKAHQKNCKMQMDSLKKNEFF"
     gene            complement(10089..10583)
                     /locus_tag="VUR46_001374"
     CDS             complement(10089..10583)
                     /locus_tag="VUR46_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HET5456787.1"
                     /translation="MSKEIDIEYYHQLALQKQKEHRKVLANLKKKPPKNLDKIAQQIH
                     QEVFEEIDCTACANCCKTLGPDFKEADITRIAKYFKMKLPAFEAEFLQVDEDGDKVFK
                     SMPCPFLGGDNLCSIYDVRPKACREFPHTDRKKIHQINHLTIKNTLTCPAAYLFVEKL
                     KDKL"
     gene            complement(10718..12451)
                     /gene="ptsP"
                     /locus_tag="VUR46_001375"
     CDS             complement(10718..12451)
                     /gene="ptsP"
                     /locus_tag="VUR46_001375"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET5456788.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFNEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(12457..12720)
                     /locus_tag="VUR46_001376"
     CDS             complement(12457..12720)
                     /locus_tag="VUR46_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET5456789.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13071..13289
                     /gene="nrdH"
                     /locus_tag="VUR46_001377"
     CDS             13071..13289
                     /gene="nrdH"
                     /locus_tag="VUR46_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET5456790.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13370..15529
                     /gene="nrdE"
                     /locus_tag="VUR46_001378"
     CDS             13370..15529
                     /gene="nrdE"
                     /locus_tag="VUR46_001378"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET5456791.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            15717..16679
                     /gene="nrdF"
                     /locus_tag="VUR46_001379"
     CDS             15717..16679
                     /gene="nrdF"
                     /locus_tag="VUR46_001379"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET5456792.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            16861..17622
                     /locus_tag="VUR46_001380"
     CDS             16861..17622
                     /locus_tag="VUR46_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5456793.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(17901..18041)
                     /locus_tag="VUR46_001381"
     CDS             complement(17901..18041)
                     /locus_tag="VUR46_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET5456794.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWDTISFDSDFMPFQ
                     QS"
     gene            complement(18131..19537)
                     /gene="lacG"
                     /locus_tag="VUR46_001382"
     CDS             complement(18131..19537)
                     /gene="lacG"
                     /locus_tag="VUR46_001382"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET5456795.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(19752..21443)
                     /locus_tag="VUR46_001383"
     CDS             complement(19752..21443)
                     /locus_tag="VUR46_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET5456796.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIENGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWVFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(21445..21762)
                     /locus_tag="VUR46_001384"
     CDS             complement(21445..21762)
                     /locus_tag="VUR46_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5456797.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(21798..22634)
                     /locus_tag="VUR46_001385"
     CDS             complement(21798..22634)
                     /locus_tag="VUR46_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5456798.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(23032..23649)
                     /locus_tag="VUR46_001386"
     CDS             complement(23032..23649)
                     /locus_tag="VUR46_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456799.1"
                     /translation="MATKKSFKALVVGLGIVSIFSSALPMVSGSVFADSALTTVDKAN
                     DIVLNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEELSKNIGISVQE
                     ASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAGWHLKQFAVNPV
                     TSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            complement(23908..24888)
                     /gene="lacD"
                     /locus_tag="VUR46_001387"
     CDS             complement(23908..24888)
                     /gene="lacD"
                     /locus_tag="VUR46_001387"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET5456800.1"
                     /translation="MALTEQKHVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            complement(24890..25819)
                     /locus_tag="VUR46_001388"
     CDS             complement(24890..25819)
                     /locus_tag="VUR46_001388"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET5456801.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTINRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            complement(25830..26345)
                     /gene="lacB"
                     /locus_tag="VUR46_001389"
     CDS             complement(25830..26345)
                     /gene="lacB"
                     /locus_tag="VUR46_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET5456802.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(26376..26801)
                     /gene="lacA"
                     /locus_tag="VUR46_001390"
     CDS             complement(26376..26801)
                     /gene="lacA"
                     /locus_tag="VUR46_001390"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET5456803.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGRDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(26959..27855)
                     /locus_tag="VUR46_001391"
     CDS             complement(26959..27855)
                     /locus_tag="VUR46_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HET5456804.1"
                     /translation="MVIELKSEQLSVQFNSFGGALSSIKDAEGLEYLWQGDATYWSGQ
                     APVLFPICGSLREDTALYIDEKGQESKGKIPRHGLVRKKEFELVEQTDKSVTFAIEDD
                     ENSYQNYPYHFRLEITYSLTGKTVRTQYKIFNKETSKVMPYFIGGHPGFNCPLLDDEV
                     YEDYYLEFEKEETCSVPRPFPETGMLDFQDRSPWLEGQKEIDLSYDLFSTDAVTLDEL
                     QSRTIALRSRKHDKGVKVHFAEFPNLIIWSTLNKGPFIAFEPWSGLSTSLEEGDHLED
                     KKNVRLLEANQVEEIGFEIEVL"
BASE COUNT         8549 a         5925 c         4901 g         8615 t
ORIGIN      
        1 aacaagggat tttcttgtca agaatatttt ttcacaaact ttttagcgtt tggattttgc
       61 taaagattca aatctcttca taatcacagt taaacgccaa cggtagagcg ccccgctcac
      121 aatcaaacta ataatcaagc cgatccagta agaataagct ccaaaatctg ttagggaatc
      181 aaatagcgta gccacaggga ttgctacgcc ccaataacca agcaaaccaa ggtaaaaagg
      241 aataactgta tccttatacc cccgcaaaat tccctgaagc ggcgccgcaa aggtatctgc
      301 taactggaag aaaagactat aagttaaaaa acgcgctgtc aaatcgataa attttgggtc
      361 gttaccataa agactggcca catttcccct aaaaatgtaa aggaaggtta aggtgaaggc
      421 cgcaaaaatg agggcagtcc atcttcctag accaatatag gttttcgcat catcaaatcg
      481 cttggctccc acttcatagg aaacgacaat agccatagcc gatgagatac tcataggaaa
      541 ggcgtacata agacttgaaa agttcatagc tgactggtga ctagctataa tcaaggacga
      601 aaacttagcc ataatcaagc caactactga aaagatagcc acttccgcga agacagttcc
      661 cccaataggc agacctaaac gaacgccttc cttaatttta tccatattaa gtggaattcg
      721 tttctcaagg tgtaaggctt tgagcttctc ctgtttaaat aaaaccagaa cagaaatccc
      781 aagcaagacc cagtaggcca aggatgttcc taaaccagca ccagcccctc ccagttctgg
      841 aacaccaaag gcaccgtaaa tcaagagata gttaaatccg ctattgagag ggagtaacaa
      901 aagcatgagg tacatggaca gtttggtcaa gcccagcgaa tccagcaagg aacgaatgac
      961 gctaaagagc aacaagggga taatcccgat agataaaaac caaagatagc gaaccgctac
     1021 tgccgctact gctgcttcta acccaatatg attcaagatt gttggtgcca agaaaagtac
     1081 catccccagc aagaccacag ataggcccaa ggccaaataa ataaattggt aaaaatcaga
     1141 cgcaacttct tcctttttgc ctcgaccaag atggtgacca atgataggca ccaaggctga
     1201 cacaatccct gttagaaatg taaagaaagg attccagata ctggttgcca tagatacacc
     1261 agccaagtcc atagtgttgt attgacctgt cattgcagta tcaacaaaag aggcagaata
     1321 attggcaaat tggtagataa ggattgggaa gaaaattttt aaaaataata ctaacttctc
     1381 tcgtaaacac tttgtcttat acatacttct ctttctattc tgatttatct aaaccaaaga
     1441 gtttcagacc atagtttttc aaacttagcg gaggtttatt agattttgaa gtagtatgcc
     1501 aacacgcaca tgtacgacaa taatagcttc taactaaacc tccgttatca tattgaaccg
     1561 catggtcagc tttttcttta gtttcatatt gaattttaga acgattagat gtgggacagt
     1621 aaattccgct attagatttt gcttgtctct ccctacgttt tcgaaaataa ttcatattcc
     1681 aactcctatc aagcttgata gacgatttgt cccttacaga tggtgtattt aacctgccct
     1741 tttaaggttt caccgatgaa tggtgaatta gctgctttcg aagcaaaatg ggagtccaca
     1801 aggcggtcag ccttagcatc aaaaatagtg atgtccgctg gaccattctc agccaagtaa
     1861 cctgcttcaa aattgtaaag cttggatggg ttgtatgtca ttttttcaag taattccatc
     1921 aagcttaact caccagcttc caccaaataa gttaaaccga gagacagaga ggtttctaag
     1981 ccagtcatac cagatggcgc tttggtaata tcctcaacat ttttttcatc tacatgatga
     2041 ggcgcatggt cagtcgcaat aactgtgatg acacctgact tgagaccttc aatcacggca
     2101 cgacggtctg attccaaacg aagcggcgga ttcatcttgg cattacttcc ttgtgtcaaa
     2161 aggagcgctt cggtcttaga aaaatgctgt ggcgctactt ctgctgtgac ttgcgcaccc
     2221 aaaccttgag caaactccac tactttaaca ctttcttcct tagacaaatg ctgaatatga
     2281 acatgggcct tggttgcata ggcaatcatg acatcacgcg ccatcatagc atactcagcc
     2341 accccagtag caccgcagat atgaaaatgt tctttagcaa tattttcgtt aaagccaaga
     2401 acaccgttca atcctggatc ttcctcatga aggctaataa aggtattgag ttttttggct
     2461 tcctccatgg cttccttgac aactttactg ctttcaagtg gaatgccatc atctgaaaat
     2521 ccaactgctc caacttctaa aagtgcctta aagtcagtca aatcttgccc attaaaattt
     2581 ttagtaatgg tcgcaaccgt cttaacatta atcttatctt tggcagctga ctggagaact
     2641 tcttgcaaag tctctacatc tgaaatggtt gggctagtat tagccatcat gacaacagtt
     2701 gtaaaaccac ctgcagcggc tgctagggca ccagtatgaa tgtcttcttt atgtgtttga
     2761 ccaggttcac ggaaatgcac atgaatatcg accaaaccag gagcaaccac aagaccacta
     2821 gcatcaatcg tttctgctcc ttcttcagtg atttcaggcg caattttgat aattttccca
     2881 tcttgaacta agacatcaca cacttgatcc aaaccagatt tgggatccat tacacgacca
     2941 tttttaatta gtagcatctg ctttctcctt tattcataga aatcaacttg ggtatccaac
     3001 aatttatccc catcataaac aaacttggct gaaaagaagg gtttgtcctc taaaagccac
     3061 tcaacaaagg tgtggtcacc ttcccaagtt ggcttgctca aaacttcatc atagggaacc
     3121 cattctagcg ttccctcgtt acagtcaatt aagtcaccct cgaactccgt cactttaaaa
     3181 acataggtgt accagtctaa atctggtgta aattcaggaa aagtgatgac accttttaga
     3241 actggcttgg ctttgagccc tgtttcctca aggatttcac gcgctgcaca ttcctgaggc
     3301 gtctcaccac gctctagctt accacccaca ccaatccatt tcccttcatg gacatcattt
     3361 ggcttcttat tacggtggag catgagcagt tctttcccat tatcaatgta gcaaattgtc
     3421 gctaactgag gcatattttc tccttatcta agccaatcga ttggctcttg tcctgtctct
     3481 tttaataatg cattggcctt ggaaaaaggt ttggaacccc aaaatcctct ataaaccgac
     3541 aaaggacttg gatgggctga ttcgataatc agatggtgag gattggtaac taaggccttc
     3601 ttcttgcgtg cataagctcc ccagagtata aagactactg gtttatctaa ttgattgacc
     3661 acctgaatca cagcatccgt aaaaggctcc catatctgcc cagcatgacc attggcctgt
     3721 acagcaggaa ccgtcaaaca agcgttaaga agcaagactc cttgttcagc ccaagctgtc
     3781 aaatcatgag atttcttaac cccgatatca tctgacaatt ctttcaagat attttgcaag
     3841 gatggcggag ctgggataga gtcaggtaca gaaaaactca agccctgcgc ttgacctggc
     3901 ccgtgatagg ggtcttgccc tagaatcact accttaactt cttcaagcgg tgttgtcaag
     3961 agagcctgaa aaaccttttc cttgggtgga taaatagttc cctgagcata gacctgttcc
     4021 ataaactgat tgattttccc gaaataacct ttaggcaatt gttcctttat caaagcatgc
     4081 caagacgagt gttccatagc caactccttc gtttttactg cctctattat agcaaaaagt
     4141 ggctatctaa accacttttt acagtttaaa ggataatact ctttaatatt attaactttt
     4201 tgttcgtagg catattttgc tacatgatct aggtatatat caaaaaagtc atgaggaaaa
     4261 tctcccatac agccattacg attcatattg aggctatatt ttcgattagt aagataattc
     4321 ggaaatatat ttcctattac tctaagatta tctacttgtg aatcccttct cccaatataa
     4381 tccccttctt tgactaatga tggagatttc caagtaaaaa ttaaatcgcc agagaaattt
     4441 ttcttatcaa aaaacttaaa aagagattga taaatactat ttgctaattg acaagtgtca
     4501 gatgtaaatt cataattaac agtttcatta aaatcaactt cagacatttc aatgtactct
     4561 tcaatagtaa tattagcttt ttttgtagtc attagctcgt atcctttaaa atgtaatctt
     4621 ttcaagaata tttttatcca aacaatccag caagtcttgg taagaatgga cttcgtaagt
     4681 tggctgggct tgtgtgtgat tttcgaggtg atgagggttg taccagatcg tgtcaattcc
     4741 agcattattg ccaccttgaa tgtcggcggt tagagaatct ccaatcatca gcgtcttttc
     4801 tttgctaaag ccagcaatct gctgaccgat tttttcataa aatagagcat caggcttttg
     4861 agtttgcaat tgctcagaga taaagacttg attgaaataa ggttctagac cagattgagc
     4921 caaacgtcct gtctgaatgg cagtaatgcc atttgtcgca gcatacaagt cataatcacg
     4981 atcaatgagg ctgtccaaga gatcatgagc gcccgatagt gtttgtccct gctgggcgag
     5041 gtaaaattgg taacgttggg caagaaaact accatctttt ccctgtccaa aatgagaaaa
     5101 taaacgagaa aagcgcgtgt taaccagctc ttgtttactg attttcttca gctccaagtc
     5161 tttccagaga gccttgttca taggaacgta ataatcttta taagcctgaa tatccgcaac
     5221 tccttcttct tttagaagtt gggtcaaagc cacatcctca gcagcatcaa aatcaagaag
     5281 agtgtggtcg aggtcgaaga gtagaaattt gtaggacaat ttgaggtttt cctttctgaa
     5341 aattcattaa gaacattata tcataaagca cctcatacaa ttaactaatt taatcacttg
     5401 aaaaaaattc gaacactatc ctatacaatt gacagctcaa atctttcaga atagaacaat
     5461 cctaactatc gaacaccctg acttaataaa tatccatgtg attctaaacc tagaattcct
     5521 ataaactaaa tgttttcgta ctcttctaag taattgattg ccttaaactt taatttttga
     5581 aggattctaa agctagaata gtctcatcac aatcagtttt gaatgattca caatttagaa
     5641 acactatagg tttactcttg ttaaaataaa aaggaactgc ccaaagcaat ccctttttat
     5701 ttacttaaaa tttgatagtt gagataatca atagcccacc tataaaaagt gttatagtaa
     5761 aattccttat ttattgattt caagctccga caactgtgtt tgaataactg acagttctgc
     5821 accagcctga agaagagcag ctgcagtata agcaccttct acaattggaa ccctattgat
     5881 catgatactt ttatcactga aatcagccac catttctaag ttcattttag cagaacctag
     5941 gtcaaaaaag gctaataaag tatctgctgg attttcggaa acaaccctat ctacttgatc
     6001 aaaacttgtt ccaattcctc catcttcggt tcctcctaca taagtaattg gaacatcttt
     6061 agctacttca ctaatcagtt caacaagacc ttctgcaatg tttttggaat gtgaaacgat
     6121 aacaagacca atactttcca tcaaaccacc ccagtttcta aaatagcagt aaagagtaat
     6181 cctgatgaga atgatccagg atcaatatgt ccaagagaac gttctcctac ataagatgct
     6241 cttcctttag ttgcaagtaa atctttggta gcattcacta ccttatcaat aagctcatga
     6301 gtcaattggc catcagacaa ggcagcaata gcaggagtcc aaacatcaac cattgtcttc
     6361 tctccaacta ctgctttctc acgtttgaca atcatatcca aaccactttg taagatttct
     6421 tctaattttg aatgagaatc agccttggac attcccataa aagcagagcc atacaaggga
     6481 ccagaagcac cgcctacctt actcagtagt tgcattgaaa caactttaaa cacatcactg
     6541 cttgtctcaa attgctttcc ttctaaattt tccataactg cagccattcc acgcgccata
     6601 tttccaccgt ggtctccatc ccctatagga gtgtctaact cactaaggta atctttctgt
     6661 tcttgaatct tttcattaaa aagcttcatc cattcaagtg cttgttcagc atttatgcga
     6721 catttcctcc ttgagtttta ccaagctggt gtagtaacag gtgcatttag agcatccaac
     6781 cattcatcat ttgccaatcg aatcaatgtc aatgacaagc cagccatatc gattgaggtc
     6841 atatagttcc caattttctt aaatgacaac tcaacacctt tttcatggag taatttagcc
     6901 acatcatttg caaatacgta ttgctccata agaggggtgc ttcctaaacc attgatgaga
     6961 agcccatagc gttcaccagc tttaagttgg aaaccttcag atagtttttc aaccaattct
     7021 gaggctaatt gtgctgaagg ttgcattttc tctttcttat atcctggctc accatgaata
     7081 ccaactccat attcaaattc atcatcttcc agaataaatc ctggtttccc aacctcagga
     7141 acggttgctc cagacagggc tagcccaatt gttttaattt ctaagacaag tttatcggcc
     7201 aagtccttca tttcagataa tgatttacca gaacgagctg cagcccccaa aattttatgg
     7261 actaatatag tacctgcaac acctcgacgc ccttgggtat agagactatt ttcaacagcg
     7321 atatcatcat caaccacaac gcttgctaca tcaatacctt ccatttcagc aagttcttgt
     7381 gcaatttcaa agttcataat gtcaccagaa tagttcttga tgaccatgaa aactccagca
     7441 ccttcatcag ccgccttgat ggcttctaaa atttggtccg gagtaggtga agtgaagact
     7501 gctccacaaa tggcagcaga caacattcca tctcctacaa atccagcatg acttggttca
     7561 tgtcctgaac ctccacctga aatgagtcca acttttcctg tcttttctac ctttctaacg
     7621 atgacatcaa aaccatctaa gcgttctacc aagtcatcat gcatgaatga caatccttgc
     7681 aacatttcat caacaacttg tgtcggttta tttataattt ttttcatgag aaactccttt
     7741 cggcatttac ttttgttttc gctttcatta tatatttttt attgctggat gataagggac
     7801 agattctatt atttgtcccc ttttaaaccc gtttaaaaca tttttttggt aaaatgaagt
     7861 aagtaaaaga aaggcttcct atggcatcat cactcattac aaaaaaacgg attgccaagg
     7921 catttagaga cctattagct actagagaat ttgacaaaat ctctattgta gatatcatgg
     7981 aatcagctgg cattcgtaga cagacctttt acaatcactt tcttgacaaa tatgaactgc
     8041 tagactggat ttttgaaact gacttaaccg agtatattac caataacttg gacttcattt
     8101 cgggccaaaa actattacaa gaattatttc tttatttcga acaagagcgt gacttttata
     8161 ttcaactttt tgatattcaa gggcaaaata acttctatga ccaatttatc agctactgtc
     8221 gcttgcttgt atcaaaaatt ttaagagaat atggtcagat tgatatcgat tcatctgcct
     8281 atacttgttt tttgttagac tatcattcac atgctctagc agaaatcgtg aaggcttacg
     8341 tcaataaaaa aagtccagtt ccacaaccag actttctaat catgacaatt attggaaaga
     8401 gaccacaatg acatttattt caaatcataa acaaaaaatt atttcaagtt acatttcagc
     8461 aactgtcagc agtcatcctg aattagaaaa acaccctact ttaccactag tctatcaaaa
     8521 aaatcgcaat cctcatcagg ttccaatatt gtcgggtgga ggttccggtc acgaacctgc
     8581 gcatattgga tatgtgggag aaggcatgct taccgctgct atctatggcc aattatttac
     8641 tcctcctaca agaactgaaa tcttagagtc cattcgtttt ttaaacaatg gtcacggtgt
     8701 cttcatcatt gtaaaaaatt tcgaagcaga catcaaagaa tttagctggg ccattaatac
     8761 tgctagacaa gaaggaatta aggtcggcta tagtctagca cacgacgata tttctattga
     8821 acctcacaat agatttcaaa ttagaggaag agggcttgca gggactattt tacttcataa
     8881 agttctagga tatgcagctc aaaatggtgc cgacatcgag caactaactg atttaggtca
     8941 tgaacttgct cccgaaatcg caacaattgg ctttgcaacg aaatctgcta gcctccctca
     9001 agccaccctt ccactattta acttggaaga aggaaatatt tcctatggta ttgggataca
     9061 cggtgaagaa ggttatcgta ttgtcccatt tcaatcatcg gaaatcctgg caaatgaaat
     9121 tataagcaaa ttaagattgc actatcattg gaaaaagggt gatcaattta tattgcttgt
     9181 aaataatcta ggcactacta gcaacctaga aatgggcata tttatcaatg atatccttca
     9241 actcttagaa attgaaggag tcactattac ctttataaaa tcaggaacat ttatgaccag
     9301 tctggatatg gcaggtatat ccgtaactct ttgccctgta aaaaataaac aatggttaaa
     9361 agcgctcaat gctccaacga cagcttttgc atggtaattc tattctataa ctcaaaaggg
     9421 ctacgtcact tgatagccct tttaatctta tctcatgttt aaaagaattc attctttttc
     9481 aaagagtcca tctgcatttt acaattcttc tgatgtgctt tgatcttttt tagagcccaa
     9541 tcatagtgac tggaggtgct actgacaaag taggaaccta gacttgttcc tcccgtccac
     9601 ttatagatac ctttggcaaa gagttcgtca ttgctgaagc cttccatcaa ctctaaaacc
     9661 tctctatgtg attgttctag gagtctagtc gcttcttcta aggaggtttt ctggtgcttt
     9721 ttccaaatag tgacattcat cttcccataa gttttccaat tataaggttc agggagaaaa
     9781 ggtctctcat gccccttttg attagaatgt acccaagtca aaagtaactg ctgccattca
     9841 tagagatgga tcagaacatc tcttagattt ttatctcttt tccagtgcgc ttcctttttc
     9901 ttttggtctt ttgaaaaatc aaatggagtc tgtagctcat cttcacttag ttgggagatg
     9961 aaacggttga gcttgtcata gttttcctta gaggctagca ctagctcctc ttttgttttt
    10021 ggtctaggca taggagtact cctttcatat ccctagttat tattagagat tttttatcct
    10081 ttaaatctct acaacttatc ctttaatttc tccacaaaga gataggccgc tggacaggtc
    10141 aaggtattct taatcgtcag atggttgatt tgatggatct ttttgcggtc agtatgaggg
    10201 aattcacgac aggcctttgg acgaacatca tagatagagc agagattatc tcctcctaaa
    10261 aatgggcaag gcatggattt gaaaaccttg tccccatctt catctacctg cagaaactcc
    10321 gcttcaaaag ctggtaattt catcttaaaa tacttggcaa tacgagtaat atccgcttct
    10381 ttaaagtcag gtcccaatgt cttgcaacag ttagcacagg cggtacaatc aatctcctca
    10441 aagacttctt ggtgaatctg ctgggctatc ttgtctaggt ttttaggagg ttttttcttt
    10501 agattggcta aaacttttcg atgctccttc tgcttttgca aggctagctg atggtaatac
    10561 tcaatatcaa tttctttaga catggtttct ctcttattct atttgtttcc ccctattata
    10621 tcatgcctct gactcattga aaagtggact ttataagacc atacttttcc aaaatgcgtc
    10681 aaaaaaacct tgcaactagg ttacaaggtt aatgacatta atcgaaatta acgtattctt
    10741 tttgaagttc aaggacttct tccattgttg aacactctgt aagggcacgg ttagcgtact
    10801 cttccatctt agcagtatct aatttcttca tcaagctacg tgtacgaagg acagatgttg
    10861 ctgacataga gaactcatcc aagcccattc cgacaagaag tggaacagct gtttggtcac
    10921 cagccatctc accacacata ccagcccatt taccttcagc gtgagctgcc ttaataacgt
    10981 tgttaatcaa gcgaaggatt gatgggttgt atggttggta aaggtatgaa acttgttcgt
    11041 tcatacggtc tgctgccatt gtatattgga tcaagtcgtt tgtaccaatt gagaagaagt
    11101 caacttcttt agcaaattgg tctgcaagca tagccgctgc aggaatctcg atcatgatac
    11161 caacttggat gttatccgca actgcaacac cttcagcaag aaggtttgct ttttcttcat
    11221 taaagactgc tttcgctgca cggaattctt tcaagagcgc aaccattggg aacatgatac
    11281 gcaattgacc gtgaacagac gcacgaagaa gagcacggat ttgtgtgcgg aacatagcat
    11341 ctccagtctc agagatagag atacgaagag cacggaatcc aaggaatggg ttcatttcgt
    11401 gaggcatatc gaagtaagga agttccttat ctccaccgat atccattgta cgaacgacaa
    11461 caggtttacc gttcattcct tcaagaacag ccttgtatgc ttcatactgc tcatcttcag
    11521 ttgggaagtc ttgagaatcc atgtacaaga actctgtacg gtaaagtcca acagcttctg
    11581 caccgttgtt gttaacacct tcaacgtctt ttggagtacc gatattagca gccaactcga
    11641 agtgtttacc gtcagcagtc actgtttgag catctttcaa gagcgcccat tcagcttttt
    11701 gtttcgcata agcttcacca gctgctttaa attctgccgc ttgttcatca gttgggttga
    11761 taataacctc accagtgatc ccgttaacag caaggatgtc accgtcttta acgatttcag
    11821 tgatgttgtt tgtacctaat acagctgcaa tttcaagtgt acgtgccatg atagctgagt
    11881 ggcttgtacg tccaccgatg ttggttacaa aagcttttac aaaatttttg tccaattgag
    11941 ctgtatcaga tggtgtcaag tcatgtgcaa tcacaatcac ttcttcattg atagaagctg
    12001 ggtttggtaa ttttttacca agaaggtttg ccaatacacg ttttgtcacg tcgcggatat
    12061 ccgctgcgcg ttcttgcatg tatgggttgt cttccatgcc ttcaaagata gtgataaaca
    12121 tatctgtaac ttctttcaga cctgcttctg cattcacttt cttcgcacgg atagtttcct
    12181 tgatttggct gatcatttct gggtcagcaa gaaccattaa gtgagcatca aaaacttgag
    12241 ctgcttcttc accgagcgta cctactgctt tctcgcgaat aacagaaagc tcgtcttgtg
    12301 atgcctgtag agcggcatca aggcgagctt cttctgcgtt tgtatcttcg actgtaatag
    12361 tctcaaatga caaatccggc tgaacgagta gatatgcttt tgcaactgca acaccgtcag
    12421 atgctgcgat tcctttaagc atttctgtca tttcccttat gccaatcctt ctttttccat
    12481 tgtttctgag attgcagcga tagcgtcatc tgcatctgca ccttcagctg agatagttac
    12541 gtcagcacct tgaccaacac caagactcat aacacccata attgatttaa ggttaactga
    12601 tttacctttg tactcaagag tgatatctga agcaaatttg ctagcagttt gtaccaacaa
    12661 tgttgctgga cgtgcgtgaa tacctgtttc tgccactacg tggaaatctt tagaagccat
    12721 agtttgactc tccttttgtt ctttcttttt ttgagttata tgtgataacc cttacaattt
    12781 agtattatac catcttctag gatttttttc aagcattttc tggattttcc ttcaatttcc
    12841 tttcagataa cttgctgaaa atcttctatc ctagataaca aaacacagga tatagtttct
    12901 tcaaaaacaa tttataggat aatcattgct atttcacaat acaaacacta tatattgtgt
    12961 ttatatatga aaacaacaaa agaacaccac tatatttagt ttaaatcatt gacaaaattt
    13021 tattttctga tatactaaga tagtattaaa ttttgaagag gagttacaca atggtaaccg
    13081 tttattctaa aaacaattgt gtccaatgta aaatgaccaa gcgtttcttg gacagtaata
    13141 atgtctctta tcgtgaaatc aatcttgatg agcaacctga gtacgtcgat caagttaaag
    13201 agctcggttt tagcgcagct cctgttatcc aaacaccaac tgaagtcttt tcaggtttcc
    13261 aaccaggaaa actgaaacaa ttagcataat cttagtacat catccagaag aaactgcttt
    13321 tagggctaac ttagaagcct ttcttttgta attagataag ggaaatttta tgggattaaa
    13381 acatcttgaa gacgtgactt acttccgtct taataacgaa attaaccgtc ctgttaatgg
    13441 acaaatcatg cttcataaag ataaggaagc cttggatgct ttctttaaag aaaatgtagt
    13501 tccaaacact atggtttttg attcaatcaa agacaaaatc aattacctca ttgaacacaa
    13561 ctacatcgaa acagccttta taaagaaata ccgtccagag ttcttggaag aattggctca
    13621 atttatcaaa gaccaaaact tccaattcaa gtcattcatg gcagcttata aattttacaa
    13681 tcaatatgcc ttaaagacta atgacggtga atactatctt gaaaatatgg aagaccgtgt
    13741 cttcttcaac gccctttatt tcgctgatgg gaatgaagct gttgcaatcg atattgccaa
    13801 tgaaatcatc caccaacgct accaacctgc tactccttcc ttcttgaatg ctggacgtgc
    13861 tcgtcgtggg gagttggtat cttgtttcct aatccaagtg acggatgata tgaactctat
    13921 cggacgttct atcaactcag ctcttcaact ttcacgtatt ggtggtggtg tgggaattac
    13981 cctcagcaac cttcgtgaag ctggtgcacc tatcaaaggc tatgaaggag ctgcttcagg
    14041 tgtcgttcct gtcatgaagc tttttgaaga cagcttctct tactccaacc aattggggca
    14101 acgtcaaggt gccggtgttg tctacctcaa cgtctttcac ccagatatca tcgctttcct
    14161 ttcaactaag aaagaaaacg ctgatgaaaa agtacgtgtc aagactctat cacttggtgt
    14221 tgtagtacct gataaattct acgaattggc tcgtaaaaat gaagaaatgt acctcttcag
    14281 cccttactct gtagaaaaag aatacggtgt gccattcaat tacatcgaca ttactgaaaa
    14341 atacgatgaa ttggtcgcaa atccaaatat tcgcaagaca aaaatcaagg cgcgggattt
    14401 ggaaactgaa atctctaaat tgcaacaaga gtctggctat ccttatgtag tcaacatcga
    14461 tacggctaac cgtgcaaatc ctgttgatgg aaagattatc atgagtaact tgtgttctga
    14521 gattcttcaa gttcaagaac caagcttgat caacgatgct caagaattcc ttcaaatggg
    14581 aacagatgtt tcatgtaacc tgggttcaac caacgtggtt aacatgatga cttcacctga
    14641 ttttggtcgt tctatccgtg ctatggttcg tgcccttact ttcgttacag atagttcaca
    14701 tatcgtagct gtaccaacga ttgaccatgg aaatagccaa gcccacacct ttggtctcgg
    14761 tgccatggga ctgcacagct accttgccca acaactcatt gaatatggtt cacctgagtc
    14821 tgttgaattt acaagcatct actttatgct tatgaactac tggaccttgg tagagtcaaa
    14881 caatattgcg cgtgaacgtg gtattacctt ccacaacttt gaaaaatcag actatgctaa
    14941 cggaagttac tttgacaagt atgtaactgg tgaatttgtt ccaacatcag accgtgttaa
    15001 agaactcttc aaaaatgtct ttatccctgg tgttgctgat tggactgaac ttcgcgacaa
    15061 ggttcaagaa gatggtcttt accaccaaaa tcgccttgct gtagcgccaa atggttctat
    15121 cagctatatc aacgacgttt ctgcttctat ccacccaatt acgcaacgta tcgaagaacg
    15181 ccaagagaag aaaattggta aaatctacta ccctgctgct ggcttgtcta cagaaaccat
    15241 tccttactac acttctgcct acgatatgga tatgcgtaaa gtcatcgatg tttacgctgc
    15301 tgcgactgaa cacgtggatc aaggactttc actcaccctc ttcatgcgta gtgacattcc
    15361 aaaaggcctt tacgaatgga agagggaaaa taaacaaacg acacgtgact tgtccatcct
    15421 tcgtaactat gcctttaaca agggaatcaa gtctatctac tacgtccgta cctttacaga
    15481 tgacggtgga gaagtcggcg ccaaccaatg tgaaagctgt gtgatttagt ttctatcata
    15541 gaaacactat ttttccctaa gcagcactga taaaatcaaa tctactatgt cataacataa
    15601 tttatgtaac attttaaaag tcgggcttcc gactttttgt gcgatactcc tatagaatta
    15661 tggtaaagta gaaataattg tgagttcgca atactaaaca cagaaagaga ttttaaatgg
    15721 aaacttacta caaagccatt aactggaatg ccatcgaaga tgtcatcgac aaatcaactt
    15781 gggaaaaact gacggagcaa ttttggctcg atacacgtat tcccttatca aacgacttgg
    15841 atgactggag aaagctatct aacaaagaga aagacttggt cggaaaagtt tttggtggtt
    15901 taacccttct tgacactatg caatctgaaa ctggggttca agcccttcgc gcagacatcc
    15961 gtacaccaca tgaggaagct gttttcaata acatccaatt tatggaatct gtccacgcta
    16021 aatcttactc atcaatcttt tctaccttga atactaaggc tgagattgaa gaaattttcg
    16081 aatggaccaa taccaatcct tacctacaaa agaaggctga gattgtcaac gaaatctacc
    16141 taaacggcag cccacttgaa aagaaagttg ccagcgtctt cctcgaaacc ttcctcttct
    16201 actctggttt cttcactccc ctctactatc tcggtaacaa caaactagcc aacgttgcag
    16261 aaatcattaa attgattatt cgtgacgagt ctgttcacgg aacctacatt ggttacaaat
    16321 tccaacttgg tttcaatgaa ttgcctgaag aagagcaaga aaaactcaaa gaatggatgt
    16381 acgacctact ctatactctt tatgaaaatg aagaaggcta cacagagagt ctttatgacg
    16441 gtgttggttg gactgaagag gttaaaacct tccttcgcta caatgccaat aaagctctca
    16501 tgaacatggg acaagatcca cttttcccag attcagctga agatgtcaac ccaatcgtta
    16561 tgaacggtat ttcaacagga acttccaacc atgacttctt ctctcaagtc ggaaatggtt
    16621 accttcttgg cgaagttgaa gccatgcaag acgatgacta taactacggt ttagactaat
    16681 tctccatcac tctcaatcat caaaaagtaa actagaaaca tcaaagttat aacccaacaa
    16741 aaatatcgaa agttttgaaa acaaacttcg atatttttgt ttttgtttca ttttgttgtt
    16801 tttgtatttg aatgatgagt ttgtttatgg taagatagta gtaggaaacg aggtgataat
    16861 atgctcaaac aagaaaaatt aaccaaaatt ttagagatag taaatagtaa aggaaccata
    16921 acagttaaac agattatgga cgaaatagcc gtttcagata tgactgcaag gcgctattta
    16981 caggaattag ctgataaaga tttgctgatt cgtgtgcatg gtggagctga aaaacttcga
    17041 accaactccc ttttgactaa tgagcgatca aatattgaaa aacaagccct ccaaacggca
    17101 gaaaaacaag aaatagccca ttttgcaggc agtctagtag aagaaagaga aactattttc
    17161 attggaccag gaacaacatt agagtttttt gcgcgtgagt tgcctattga caatatccgc
    17221 gtcgtaacca acagtctacc tgtttttctg attttaagcg aacgaaaatt aacagatttg
    17281 attttgatag gtggaaatta tcgcgatatt acaggtgctt ttgttggcac attgacccta
    17341 caaaatctct ctaatctcca attttctaaa gctttcgtta gctgtaatgg tattcaaaac
    17401 ggagctctag ctacttttag cgaggaagag ggagaggctc aacgcatcgc tttaaataat
    17461 tctaataaaa aatatttact cgcagatcat agtaagttca ataagtttga tttttatact
    17521 ttttataata tatcaaatct tgatactatt gtttcagatt ctaaactaag tgattcaatc
    17581 ctttttaagc tatctaaaca cattaaagtc atcaagcctt aataaactga aagagcctgg
    17641 gtaacaactc aatttcagaa gaaaaaaagt aaatcttccc acaataaaac gcatagtatc
    17701 aggtgtttca acacctgata ctatgcgttt ttctatatca aagacttttt gcccaattcc
    17761 tcaaagctat gcattgagaa atctgcgact cgcttcctag tttaaagttg ctctttgatt
    17821 ttcattgagt ataagcaacg tgattagata agagttttac agagtactaa atataagatt
    17881 taactttttt gagaaattgg ttacgattgt tgaaacggca taaaatctga atcaaaggag
    17941 atagtatccc attctttacc agtcgagaca taccattttc caagactttt caattcttca
    18001 ctcgtcaaac acggtatttg agagcatttt tcgaaattta taatataaac tttttttcat
    18061 aaatagattg gataaaatct ttgaacatct ttttgactca ctaaaattct atatctaatg
    18121 actaattcta ctagtctata atctgagttt ccgctacttt cttgtaccag tgagctgatt
    18181 tcttaggata acgttcttga gtttcaaaat ctacgtagaa gagaccataa cgtttctcat
    18241 aaccgtttga ccatgagaag acatccatta atgaccaaat gaagtaacct tttacattag
    18301 ctccatctgc aatcgcatca gacaagatct ccaagtgttg tttcacgtaa tcaatacgac
    18361 catcatcgta aacagtgtta tcaacgaact catctttata gccgagacca ttttcagtga
    18421 tgtaaatttt cttgtagtta ggataatctt tcttcacacg catgatttgg tcatacaaac
    18481 cttgagggta gataatccaa tcccaatccg tgcgtgatac atagtcagga gctacacgac
    18541 gaccaatacc tttgatttga tacttagagc ttcctttttc acctttacca ttatggataa
    18601 tttcagtttc tccatcaaag gcttccatcc agtcactcat atagtagttg attcctagga
    18661 aatcattcaa gtcttttgca gcttctaatg ctgtaaaatc ttcttcacga agatccaaac
    18721 taccaccatt gactgataag atatggttga caccttccat ggtttcagct gaatagcgac
    18781 ctagataagt tgcgtctaag atgaatttat tgtggatgat atcttccaac tctgctgcac
    18841 gaacatctgc tggattttca ggatctagag gatatttagt aggcagggcg tgaacaacac
    18901 caatttcccc tttatagcct ttctctttgt acaattttac cgcgcatgca tgagacacca
    18961 tcatattgtg gtgtgattga aagactttgg caaggtcgta ctggatacct ggagggaatt
    19021 tcccaaccaa atattgacca tcaccgattg gtccaatttc attgaaggtt gtccaatagt
    19081 ttacttctgg aaattcttca aaacagaagg cagcgtagtc tacaaaatgt tcgatatttt
    19141 cacggtttaa gaagtctcca tttgagtgga gagcttctgg cgtgtcaaag tgatgaagag
    19201 ttacaaaggg ctcaacatga cgtttgtgac actctgcaaa taaattatga taaaactcaa
    19261 cacctttagc atttacttga ccataaccag tcgggaaaat acgtgaccag gcaatagaaa
    19321 ttcgaatgcc attgacacca tactcttctg ctagcttgag atcaactgga tatcgattgt
    19381 aaaaatcact ggctggttct gcagtgtacc agtagttatc ttcaagatat ttatcccacg
    19441 ctactggtcc tttaccatca gtatgtgtag caccttctgc ttgataggca gctgttgcgc
    19501 caccaaaaat aaagtctttt ggaagtgttt ttgtcatttt tttcacctat ttcttgattt
    19561 aaataaagta aaagtgagag gagaggagtc agtgagccat ccttctccat ctcacttctt
    19621 gtaccaagtc accgaattgt gacatgagga ggtaaaaacg atatcttttt accgacgaat
    19681 taataaggcg attaggaaat tcgccatagc gatttccgta acgataggag actgtttcac
    19741 agttcctagc cttaatcgaa ttgttcttgt acgaatgcta gggcaccttt tccatcacga
    19801 gttaatttga tgtattgagc gccttctgtt ttcgctagtt taataccgag cttatctgtt
    19861 tctgccttca tatcttcaaa gtttgaagca acttgaggag caaggataac caaatcaaac
    19921 tctggtaaca tttcacggtg agcaccatag ccgcctgctg ctgctttcac agggacattg
    19981 tattctgctg ctgccttatt caaagcattt gcaaggagtc cacttgtacc tccaccagca
    20041 cagagaacga ggacatttgt ttcttcagtg atggtatttt gtgctgcatc gacacctgct
    20101 ttttcaagaa tagcatccgc ttttgcagtg ttgaagtttg cagcaacttt ttctttcaat
    20161 tcatcattag acttacctga acgttcttct tcaagaattt gttcatcata gaccttaagg
    20221 aatggatagt aaatgacaac gtcaaccacg attagaagag cagcaagaat gaatgataga
    20281 acttggaagt tagttccaag aactagacct agtggagctg gggttgtcca tggtagatta
    20341 gcagtaaatg aattcattcc aagtgtttca ataaagaatt tgaaaaccca tacgtttgcg
    20401 ataggagcaa aaataaatgg aatgaagaag attggattta atacaagtgg tgcaccaaac
    20461 aagattggtt catttacacc gaagaaggta ggaactactg aagcacgtcc gattgcacgg
    20521 ttacgttttg attttgttaa ccacataaac atgaatggaa caaccagtgt cgcaccagta
    20581 ccacccatgg taacgataaa catttgtgta ccagaagtaa gaatcttgtc agcgtgcata
    20641 ccttgttgga gaaggttcaa gttgacttca gcatttgcat aggtaatcgc tgcgatagca
    20701 ggttcaacga tagatggacc atgaatccca acaaaccaga agaaggcaaa ggcaccaaag
    20761 ataatggtaa taccaaggta gccatcagct gcagagaaga gtggtgcaaa gaatttaccg
    20821 attgattcag ctacgcttgc accaacaaaa tgacgagcta gtaaatcaag agcataaagt
    20881 gaaacaactg agagagtgaa tggaatcaca tctttaaaga cttgtgagat atttggtgga
    20941 acttcgtcag gcatacgaat agtgacgttg ttcttaacac aaaccttata gatggctaca
    21001 gtaacaaagg cagcaaggaa ggctgaaagc aaaccttttg tccccaagaa tccagtagct
    21061 agaccatttt cgataggatc agctgccaac atcaacaaac caacaatcgc tgctaacagc
    21121 gttgacatat agttgatttg attggttttc tccatgctcc ggtttactga gtcggtcaat
    21181 gacttagctg ttgtaccagc taccaagaga gccagaatac ccatagaata gctataaggt
    21241 ttcatcagaa aggctacaac ttcatcagac catttaaagc cccatgaatt tggtacaaag
    21301 gcaatcaaga taaagatact tgagaagaga ataacaggca tacctgcaat gaaaccatct
    21361 tttatcgctc ttaagtatat atttctcgat aatttctcaa agaaaggctt tcctttctca
    21421 ataaaaatta ttaacttatc cattttattt aactcctctc ttgtaaagtt caattaaatg
    21481 gtgcattagg tcttttaaca agatagttgt catcaagtga tcttgaccat gcatcatggt
    21541 cacactatac gctaagtcct caccagaagc ttccttagtc aatagacttg tttgcgcgtg
    21601 gtgagcctct gcaatacagc taccagcttc ctctaccaga gcgtccgctt tttcaaaatc
    21661 accagcttca gcagccttca aggcttccaa tagttttgaa cgagcatcgc cagcataggc
    21721 tacgatttca aaacctaaca atgttacttc ttctctattc atgatagaat tctccttata
    21781 tagttttaaa taaattttta tgacaataaa cgttggatat gtagaactag ataaactcgt
    21841 tcacttttat acaaatcaag acccgtatgt tgcgtaatca catcatagat cttggaacca
    21901 atctcgaagg cttttggata ggattgttta atatgatctt ccatatccag aagtgattgg
    21961 ttatcatctc tagatctgtc taaataatcc aagaaataat tcaaatggat cataaagcga
    22021 tcatagaaat ggttattctt tttagttcgt tgaattgcat agtccgttaa aacttcttca
    22081 acattcctga gaatttcttt cctcttatca atcgactcca caagttccac ttcattttca
    22141 ccttcagcat taatgaaatg ataagcaatc cgaataattt cgtcctcagg aaaatgatct
    22201 gctagcttct gacggtaaat ttcaaaagct tcatttgcga tttgaaaagc gacaggatac
    22261 ttagcagaaa tatctggcag attactatcc ttgtaccttc cttgagttag agcttgataa
    22321 gaacagtaaa tatgatctgt caaggttaca tagagatact cttgaatcgg ataatgatat
    22381 ttctttgata gcttatcaat gatttcatag gtcactgtga taaaatcaag cggaacatct
    22441 ttgagaagag ccataaagtt ttctctggac tcttcggtct tcatccgaaa gattttctca
    22501 acatgatttt cagcaatcaa atcccccttc ttctttccga atgcaatccc cttaccaatt
    22561 acaatcacct cttctccctt atcatttctg acaagcgaga cattgtgatt cattggattt
    22621 agaattcgat acatgtcaac ctccttttat atcttaaagg tatataagta caaaaaatga
    22681 ccacaaatga actagaaaat cagctgattt ctaattcacc tgtgatcatg cctaatatta
    22741 cttagtaaca ctcaccttgt attaacttgt gatttaagta tagcacaagt cggttgtttt
    22801 gtaaaccttt acatacaact ttttttaaaa cttaactatg ttctaaaatt catcaaacag
    22861 aggctctgtt tttatttatt tttgtaaatc aaaacaaaaa caggaagaca gaaaaataaa
    22921 aaagtagcta catttttaaa attcattaag tctaataaac aaagaacaca agaaactata
    22981 aaacaaaata cagttatttt tttaaaagaa tgattcataa agaaataacc tctaaggtaa
    23041 atctatggtg taaacaaggt tcacaaacgg cacttctact gtagctacag caactgtcca
    23101 ataattttct acagcagttt ttacagccca gccaatcgca ccacttatta cagcaacaaa
    23161 tccagatgta acaggattaa ccgcaaattg tttcaaatgc catccagcat atccagtagc
    23221 gaaagctcca gcagcccagc cacccatccc cctcacttga ggaccaagat tgaaacgaaa
    23281 acctacagga cctctttcgt aaacgttggg caactctttt acagcttcat acatcaaact
    23341 tgcttcttgt acagaaatac caatattttt tgataactct tcaggagtgc cttttaaatt
    23401 tatatttcca aatttatcta cataaaaata atcttccaaa atttgaccag catttacaat
    23461 atcttctgaa accgaaacat tataaaattt attcccatca acattcaaaa caatatcatt
    23521 tgctttatct actgtagtta gggcactatc tgcaaataca gaaccactaa ccataggtaa
    23581 ggctgatgag aatattgaaa caatacctag tcctacaact aacgctttaa aactcttttt
    23641 agtagccatt tatcttctcc ttttataaaa caatgagtga aatgtgcatc taaatatagt
    23701 ttattctggc aatattgttt ccgtattttt tccttcctag ctcgtaaaat aaactatatc
    23761 ctatttttat tatacttcat atagttactt tctaattcat attaacttgt gatttaagta
    23821 tagcacaagt aagttatttt gtaaaccttt acatacaact ttttttaaat ttttttagat
    23881 tcatgttcct aaactaggag gactttctta cacgcgttct ttccatgaag ttgctgttct
    23941 ttgaagaact ttgttgagtt cgtcaatgtt ttcaaatcca gttgtgcgaa gccattcgcg
    24001 agctgctgct tcaccatctt tgatgtaagc ttcaactgat cctgcccatg tagcacggcc
    24061 acaaagaact ccgttaaagt ttgcacctga ttcatgagca aatacaagag tatcttggaa
    24121 gagtttagct gatacaccag cactcaagta gatgtatggc aagttcgttg cttcatcttg
    24181 cgctttgaag aaggctgctg cttcttcacg tgtataaact acttcacctt cagcgaagcc
    24241 ttcaacatat ttaatgttaa caggaacttc aactttcaaa acatcaatgt taaagcgtgg
    24301 gtctgaaaag actttcatag cgccgataac tttgtgtggt tttactttag cgtattctac
    24361 agaacctgca tccgcaattt tttcatcgta agcaaggatt tcaaggaaga atgggatatc
    24421 ttcagccaca cactcagaac cgatgcgttc gatgtaggct tgtttttctt gattgagttc
    24481 gtctgagcta tctacatcat agtaaagcaa gaatttaact gcatctgcac cttcttcttt
    24541 aatacgtttt gcagaccaaa catccaagca gtctggcaag cgttttgtgc ttgttgtgtc
    24601 ataacctgtt ttttcataag caaggagaag accagctttt tcatcaagag ctttagttgc
    24661 tggaagtcca tactcagggt caagaagcat agatgaagca tatttagtca attcatctgc
    24721 taccaagact ttaagttctt ccatttgggc cacagttggt tcttctgttt ggtgttgagc
    24781 catgaggcgt ttcaaagcac cacgttggtc aaatgcaaga gctgagatga taccattttc
    24841 atcagaaagt ttttctaagc gtacatgttt ttgttctgtt aaagccattt tatacctctt
    24901 ttactattaa ttgatcatat agagcttgat agttggccat gttgacatga ccagtcattt
    24961 tttcttgagc attgagcata ccaaggacat ttgccttgat gagtaattct gcatccgatt
    25021 ctttgtgaag aagtcctgaa gaaattcctg ccacagtaga gtctccagat ccaacaggat
    25081 ttaccacctg aattctagga atatctacct tgtagaaagt gtcaccatgt ttggcaaaag
    25141 taccgttggc accaagtgaa acgataatcc attcaatccc tgcaaacaaa ggttcttgaa
    25201 gtacttcttt taattcatcc aaatcctcag aaacttctct tccaagaagc tgagacaatt
    25261 cttcattatt tggtttgatg actgttggtt tatggggtga ttcaagaaca gcctgaagtg
    25321 ctgcacctga gcagtccaag actacaggct tgccagcttg attagcaagt tctaccaagc
    25381 tcgcatagta atcaactgga aggccagctg gcagactacc tgagatggct actacttcaa
    25441 ctgactccaa gagttttttg aaatgttcca aaaactcttg accttcctgt tccaatactt
    25501 caggaccttt ttcaagaact tctgtttggt tgtctccgtg gagaatagcg atacagttac
    25561 gagtttctcc cttaattgag aagaaatctt tctttacttg attatcgata tgttcaacca
    25621 aaaactcacc aagtttgcca cccactaaac cagtagcaag aacagaatcg ccaaattctg
    25681 aaagtactcg ggtaacattg agtcccttac caccagccgt tttggttaca tccaccacac
    25741 gattgatagt atcaatcttc aactcatcca agggatagga aatatcgatg gatgggttca
    25801 ttgtgactgt taaaatcata ggtcacctct tagtcgtggt attctccacg atcccatttc
    25861 tcaaggaatt ctgtaaagaa gtttgcgtct gtttgttgag cattgtgact ttcaacatgt
    25921 tcaattttcg caatcaattt tttgttttct tcagttggtt tgtattcagc atggatgaaa
    25981 gcttcgatga tatcacacat aagcaattca ccagtaattt taccaccaaa accaataacg
    26041 ttagcgttca attgttcttt agcataaagg gctgttgtca tatcacgaac caaggcagaa
    26101 cgaacacctg gaactttatt tacagcgttg ttgataccaa caccagtacc acagatacat
    26161 accccgagat cagcttgacc actagttact gcttccccta cttttttacc aaagattggg
    26221 tagtgagtcc gtgtatggtc ataggtacca aagtcaatga cttcatatcc ttttgatttc
    26281 aaaaattctg aaaccgccat tttttcatca gttacgatgt ggtcacatcc aattgcaatt
    26341 ctcattttta acttaccttt cttactataa tctaattagc ccattttgtt caacatgtca
    26401 acccggattt ggtgacgacc accgtcgtat ttaccattaa caaatccttt agcgatgttt
    26461 ttagccaatt catcaccaac aagttgtgca cccatagtga tcatacgaga gttgttgtgg
    26521 ccacgagtca tataagctga acgttcgtca gatacttctg cagcaaccat tcctttgatt
    26581 tttgttgcaa ccataaatgg accagctcca taagcatcaa tcacgatacc aaggttttgt
    26641 tcttctttgt ttacttctgc agcaacagcg agagtcacat caacaaagtc tcgaccttca
    26701 gctgtaacat ccacaaggtg gaaattttct ttttctaaga aatctttcac aacttctttc
    26761 aatctcaaac ctgcagcatc tgcaccgata acaatagaca tattgtatac tcctttttat
    26821 tttttctatg ctggattcca gcagtgtatt ggctgtcttt aaaaaacagt caattagtcc
    26881 tcacaaacat aatatactac tattgtttga aaaagtcaac agtttgtgtt tgttttttgt
    26941 tatttatttt ttactttttt ataaaacttc tatctcaaac cctatttctt caacctgatt
    27001 ggcttctaag agacgaacat tcttcttatc ttctaaatga tctccttctt caagggatgt
    27061 tgacaagcca gaccatggtt caaaggcaat gaaaggtccc ttattcaaag ttgaccagat
    27121 gatgaggttt ggaaactctg caaagtgcac tttcaccccc ttatcatgtt tacgagaacg
    27181 aagggcaatt gttcgagatt gcaattcatc caaagtcact gcatctgtgc tgaaaagatc
    27241 ataactaaga tctatttctt tttgtccctc tagccatgga cttctatctt gaaaatccag
    27301 catccccgtt tctgggaaag gacgtggaac agagcaagtc tcttctttct caaactctaa
    27361 atagtaatct tcatagacct catcatccag tagaggacaa ttaaatcctg gatgtccacc
    27421 aataaagtaa ggcatgacct tgctagtttc tttattaaat attttgtatt gagtccgtac
    27481 tgtctttcca gtaaggctat aagtgatttc taggcggaaa tgataaggat agttttgata
    27541 gctattctca tcgtcttcaa ttgcaaaagt tacactcttg tctgtctgtt caactaattc
    27601 aaattctttc ttacgaacca gaccatgacg aggaatcttt cctttacttt cttgcccctt
    27661 ctcatctata tagagggctg tatcctctct caatgaacca caaattggaa agagaacagg
    27721 agcttgtcca ctccaataag tagcatcccc ttgccacaaa tactccagtc cctcagcatc
    27781 ctttatagaa gaaagagccc caccaaaact gttaaattga acacttaatt gttctgattt
    27841 taattcaatt accattattt tctccaattt cttgatagtt tataaaaaac taggctgtca
    27901 ctcctaatgg tatgacaacc tagtttcaac aatttacact ctgcgaaaat ccaattcaaa
    27961 cttcgtcagc gtcgccttga cgtagatatg
//
LOCUS       DAVDHZ010000027        26726 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000027 DAVDHZ010000000
VERSION     DAVDHZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.028"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(18..998)
                     /locus_tag="VUR46_001392"
     CDS             complement(18..998)
                     /locus_tag="VUR46_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET5456805.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELIKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(1011..1757)
                     /locus_tag="VUR46_001393"
     CDS             complement(1011..1757)
                     /locus_tag="VUR46_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5456806.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1879..2655
                     /locus_tag="VUR46_001394"
     CDS             1879..2655
                     /locus_tag="VUR46_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET5456807.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            2730..2927
                     /locus_tag="VUR46_001395"
     CDS             2730..2927
                     /locus_tag="VUR46_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET5456808.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            3144..3740
                     /locus_tag="VUR46_001396"
                     /pseudo
     CDS             3144..3740
                     /locus_tag="VUR46_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            3816..4265
                     /locus_tag="VUR46_001397"
     CDS             3816..4265
                     /locus_tag="VUR46_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5456809.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADVEMTVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            4278..4915
                     /locus_tag="VUR46_001398"
                     /pseudo
     CDS             4278..4915
                     /locus_tag="VUR46_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            5051..5356
                     /locus_tag="VUR46_001399"
                     /pseudo
     CDS             5051..5356
                     /locus_tag="VUR46_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            5346..6991
                     /locus_tag="VUR46_001400"
                     /pseudo
     CDS             5346..6991
                     /locus_tag="VUR46_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(7094..7786)
                     /locus_tag="VUR46_001401"
     CDS             complement(7094..7786)
                     /locus_tag="VUR46_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5456810.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEGGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(8030..9367)
                     /locus_tag="VUR46_001402"
     CDS             complement(8030..9367)
                     /locus_tag="VUR46_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET5456811.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSAVVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(9377..9643)
                     /locus_tag="VUR46_001403"
     CDS             complement(9377..9643)
                     /locus_tag="VUR46_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET5456812.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(9908..10294)
                     /gene="rplQ"
                     /locus_tag="VUR46_001404"
     CDS             complement(9908..10294)
                     /gene="rplQ"
                     /locus_tag="VUR46_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET5456813.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(10306..11241)
                     /locus_tag="VUR46_001405"
     CDS             complement(10306..11241)
                     /locus_tag="VUR46_001405"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET5456814.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(11284..11667)
                     /gene="rpsK"
                     /locus_tag="VUR46_001406"
     CDS             complement(11284..11667)
                     /gene="rpsK"
                     /locus_tag="VUR46_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET5456815.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(11685..12050)
                     /gene="rpsM"
                     /locus_tag="VUR46_001407"
     CDS             complement(11685..12050)
                     /gene="rpsM"
                     /locus_tag="VUR46_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET5456816.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(12068..12184)
                     /gene="rpmJ"
                     /locus_tag="VUR46_001408"
     CDS             complement(12068..12184)
                     /gene="rpmJ"
                     /locus_tag="VUR46_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET5456817.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(12209..12427)
                     /gene="infA"
                     /locus_tag="VUR46_001409"
     CDS             complement(12209..12427)
                     /gene="infA"
                     /locus_tag="VUR46_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET5456818.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(12544..13182)
                     /locus_tag="VUR46_001410"
     CDS             complement(12544..13182)
                     /locus_tag="VUR46_001410"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET5456819.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMVNQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(13333..14643)
                     /gene="secY"
                     /locus_tag="VUR46_001411"
     CDS             complement(13333..14643)
                     /gene="secY"
                     /locus_tag="VUR46_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET5456820.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDKTE"
     gene            complement(14656..15096)
                     /gene="rplO"
                     /locus_tag="VUR46_001412"
     CDS             complement(14656..15096)
                     /gene="rplO"
                     /locus_tag="VUR46_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET5456821.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(15241..15465)
                     /gene="rpmD"
                     /locus_tag="VUR46_001413"
     CDS             complement(15241..15465)
                     /gene="rpmD"
                     /locus_tag="VUR46_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET5456822.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(15437..15931)
                     /gene="rpsE"
                     /locus_tag="VUR46_001414"
     CDS             complement(15437..15931)
                     /gene="rpsE"
                     /locus_tag="VUR46_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET5456823.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(15949..16305)
                     /gene="rplR"
                     /locus_tag="VUR46_001415"
     CDS             complement(15949..16305)
                     /gene="rplR"
                     /locus_tag="VUR46_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET5456824.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(16389..16925)
                     /gene="rplF"
                     /locus_tag="VUR46_001416"
     CDS             complement(16389..16925)
                     /gene="rplF"
                     /locus_tag="VUR46_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET5456825.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VDGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(17117..17515)
                     /gene="rpsH"
                     /locus_tag="VUR46_001417"
     CDS             complement(17117..17515)
                     /gene="rpsH"
                     /locus_tag="VUR46_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET5456826.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(17729..17998)
                     /gene="rpsN"
                     /locus_tag="VUR46_001418"
     CDS             complement(17729..17998)
                     /gene="rpsN"
                     /locus_tag="VUR46_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET5456827.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(18016..18558)
                     /gene="rplE"
                     /locus_tag="VUR46_001419"
     CDS             complement(18016..18558)
                     /gene="rplE"
                     /locus_tag="VUR46_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET5456828.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(18582..18887)
                     /gene="rplX"
                     /locus_tag="VUR46_001420"
     CDS             complement(18582..18887)
                     /gene="rplX"
                     /locus_tag="VUR46_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET5456829.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(18965..19333)
                     /gene="rplN"
                     /locus_tag="VUR46_001421"
     CDS             complement(18965..19333)
                     /gene="rplN"
                     /locus_tag="VUR46_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET5456830.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(19359..19619)
                     /gene="rpsQ"
                     /locus_tag="VUR46_001422"
     CDS             complement(19359..19619)
                     /gene="rpsQ"
                     /locus_tag="VUR46_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET5456831.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(19644..19850)
                     /locus_tag="VUR46_001423"
     CDS             complement(19644..19850)
                     /locus_tag="VUR46_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET5456832.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTVRLKEVKKQIARIKTVQSEAK"
     gene            complement(19860..20273)
                     /gene="rplP"
                     /locus_tag="VUR46_001424"
     CDS             complement(19860..20273)
                     /gene="rplP"
                     /locus_tag="VUR46_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET5456833.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(20277..20930)
                     /gene="rpsC"
                     /locus_tag="VUR46_001425"
     CDS             complement(20277..20930)
                     /gene="rpsC"
                     /locus_tag="VUR46_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET5456834.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(20943..21287)
                     /gene="rplV"
                     /locus_tag="VUR46_001426"
     CDS             complement(20943..21287)
                     /gene="rplV"
                     /locus_tag="VUR46_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET5456835.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(21299..21580)
                     /gene="rpsS"
                     /locus_tag="VUR46_001427"
     CDS             complement(21299..21580)
                     /gene="rpsS"
                     /locus_tag="VUR46_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET5456836.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(21684..22517)
                     /gene="rplB"
                     /locus_tag="VUR46_001428"
     CDS             complement(21684..22517)
                     /gene="rplB"
                     /locus_tag="VUR46_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET5456837.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSCWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(22535..22831)
                     /locus_tag="VUR46_001429"
     CDS             complement(22535..22831)
                     /locus_tag="VUR46_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET5456838.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(22831..23454)
                     /gene="rplD"
                     /locus_tag="VUR46_001430"
     CDS             complement(22831..23454)
                     /gene="rplD"
                     /locus_tag="VUR46_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET5456839.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(23479..24105)
                     /gene="rplC"
                     /locus_tag="VUR46_001431"
     CDS             complement(23479..24105)
                     /gene="rplC"
                     /locus_tag="VUR46_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET5456840.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(24322..24630)
                     /gene="rpsJ"
                     /locus_tag="VUR46_001432"
     CDS             complement(24322..24630)
                     /gene="rpsJ"
                     /locus_tag="VUR46_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET5456841.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(24897..25514)
                     /locus_tag="VUR46_001433"
     CDS             complement(24897..25514)
                     /locus_tag="VUR46_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET5456842.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(25511..26101)
                     /gene="nrdG"
                     /locus_tag="VUR46_001434"
     CDS             complement(25511..26101)
                     /gene="nrdG"
                     /locus_tag="VUR46_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET5456843.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKINDGKESYEQVKRE"
     gene            complement(26094..26600)
                     /locus_tag="VUR46_001435"
     CDS             complement(26094..26600)
                     /locus_tag="VUR46_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456844.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
BASE COUNT         7713 a         5812 c         4745 g         8456 t
ORIGIN      
        1 gaatcagtct atcattttca ctcacctaga atctctctaa aagtcaaatc cccatcttct
       61 tccaaaactt ttaaaattgt atttttgtct gtaatcaaat gatttactaa attagcacgc
      121 aagacagaaa gaatcgaaga tactttcgta tcaccgtaag caacagctaa actttgagga
      181 atatttttta aatcttccaa agagattgct atcgttcttt cctgtaagtt ttcatagact
      241 tctttacctt ttgaatcaaa aaatcgacaa caaatttctc ctacagtttt aactttgatc
      301 aattctttaa agtcatcctc tgtaagcatg tctaaccatt gatgttttcc tttattgcta
      361 aaatcaccaa ttccgactac agctatatct aaatctttcc aactattttt caaattttca
      421 aaatatcttg attgcaaaat accatctgct aacaatttat tttcttgcac aatcgttgca
      481 ttcataaatg tacactctcc atgaaatttt ctagacattt cataaatcag tgtattcaca
      541 tggtatttag cgtgtatgtg actaggacca cctgctagag gatagaagtg aacatttcgg
      601 acacttttac tgtgaattaa atctactaaa ttacttaaac ttttccccca agaaaagcca
      661 attttcatat tatcatcaat tagattccta aggacacctg ctgcaacttg agaaattctt
      721 tcagataaaa ttgttggatt atcatcaaat tcatttggaa taatttctaa actttccaga
      781 ccatattttt cttttacata attttccaac ttaaacatat tggtatcaaa attctctatt
      841 tcaattttaa caattcctgc attccttgct tctgttaaca ttctactaat agaggttcta
      901 taaattccta attttgctgc tatttgtgac tgatttaagt tttcaatata atacagataa
      961 gcaattttag agagcagttt attcctatct tgattcatac acttaacctc ttacgaaact
     1021 accttaacca ttatcccagc attttctaat gtagctatat tttgtttaga aagtttttcg
     1081 tctgttatta cttcatagac ttgacttaaa gcaaatcttc ttactgtacc ccttttatca
     1141 aatttacttg agtcagttag tacaatgact ttatccgatg ctgctgaaat atattgaact
     1201 acctcactgc gcattaaatc ttttcctgta aagcccatct ctttatcgta accatctgtc
     1261 ccaacaaaag cttgatgcac atgaaaagtc tgtatcattt cttttaataa aggtcccaca
     1321 gtaacctgtg aatccttctg aaactctcca ccaagaacaa taatacgaca tgaatcataa
     1381 gctctcacaa aatttgctat aaaaaatgaa tttgttacaa tcgtaacatt tcttttttgc
     1441 ttgcaaattt cctcagcaag taaagcacag gtcgatccag attctatcat tattgtttca
     1501 ttatctgaca ccaattttac tgcttcctga acaatttttc tcttaatttc ataattaatt
     1561 gacaaacgca catttaagtc atctccacta tttaatacag catatccatg ctctctgtgt
     1621 aataaacctt ttgactctaa tttatctaaa tcttttctaa tcgttacttt cgatacattt
     1681 aatttttccg ataatgtatt aacgtcgatc ttttcatatt ctgatactaa tttaataatt
     1741 tgttccaatc ttttcatttt acacccccgt tttattctac caaaataaaa agcaaaaaac
     1801 aacaaattaa cctttcgttc gtaattgttt ttctttcgtt tttgtgatag gatagactta
     1861 tgaagaggag gaactcttat ggaaatatct aaaggaatta tttttaatat tcaacacttt
     1921 tcaattcatg acggcccggg tattcgtaca actgtttttt taaaaggatg tcctctgcgc
     1981 tgtccatggt gttctaatcc tgaatctcaa agaatgaaac ctgaaaaaat gaaagatgct
     2041 caacgagaga aattcacctt agtcggtgaa gaaaagactg tagaagaaat tattacagag
     2101 gtattaaaag acaaagaatt ttacgaagaa tccggtggag gtttaacttt atcaggaggt
     2161 gaaatatttg ctcagtttga atttgctaaa gccatcttaa aatcagctaa agaacatcac
     2221 atacacactg ccattgaaac tactgccttt gttgatcatg aaaaatttat cgatttaatt
     2281 caatatgtgg attttatcta cacagaccta aaacattata attctataaa acataaaaaa
     2341 gtgactgggg tttttaatca aatgattatt aaaaacattc attatgcttt ttctcaaaat
     2401 aaaactatcg ttttaagaat cccagttatt cctaatttta acaatagttt agaggatgca
     2461 gaaaaattcg ctactctatt taactcatta aatatcgacc aagttcaact actccctttt
     2521 catcaatttg gtgaaaacaa atatcgttta ttaaatcgga aatatgaaat ggatggaatc
     2581 aacgcacttc atcctgaaga tcttattgat tatcaaaagg tatttctgaa ccaccatatt
     2641 aattgttatt tctagtttat ttccttgaaa tgctctagct atttgcagat aacaagcatc
     2701 tatataaggt tatcaaagaa gacttcccca tgactctaaa tgaatatatc ttacaatatc
     2761 gcctgaaaca agctatagat aagatggctg aatctcccaa ctccccttta agcgctatct
     2821 ctgaccaagt tggattttca gactataaat attttgccaa agtatttaaa aagtatctcc
     2881 atatttcccc aaagaaattg aaatcactcg gaagaatagt caaataggct attcttcttt
     2941 ttgtagagaa ttttactcta atatagtgaa ttgaaataag atgtgaacat ctctatcagg
     3001 aaagtcaaat taatttatag aaatatttta gcagccaaag tgtactgtta tagattcaat
     3061 acactataga atagaattgt aggttttaaa aacgcttaca ttgttttaaa ataaacttaa
     3121 ataacacaac ggaggtatcc atcatgaaaa agaaatggat gtattatgct gcttgttctt
     3181 ctaatgaatc tgccgatgac agttcatctg ataaaggaga cggtggttcg ctagtcgttt
     3241 attcaccaaa ctcagaaggc ttaattggag caactattcc tgcctttgaa gaaaaatatg
     3301 gtatcaaaat agaactgatt caagctggta ctggagaact tttcaaaaaa ctagagtcag
     3361 aaaaagaagt tcctgtagct gatgttatct ttggtggttc ttatacacaa tatgctaccc
     3421 acggagaact ctttgaaaac tatatttcaa aagaaaatga taatgttatc aaagaatatc
     3481 aaaacacaac tggcttctct actccttata cactagatgg tagtgtttta atcgtccacc
     3541 ctgatttaac taaaggcatg aacatcgaag gatatagcga ccttctcaaa cctgaactaa
     3601 aaggaaaaat cgcaactgct gacccagcaa actcttctag cgcctttgct caattaacaa
     3661 atatgctaca agctcaaggt ggttacaaag atgataaggc ttggtcttat gtaaaagatc
     3721 ttttcacact tattgatggt atagtaaaat gaaataagaa taggacaaat taatcaggac
     3781 agtcaaatcg atttctaaca atgttttaga agcagatgtg tactattcta gtttcaatat
     3841 actataaaat cggtttaagt tcatctggtg tctataaagc agtcgctgat gtagaaatga
     3901 ctgttggtct ctcttatgaa gatccagcag ttaaactctt aaatgacgga gctaacatta
     3961 aggtagtcta tccaaaagaa ggaaccgtct tcctacctgc tagtgctgct atcgttaaaa
     4021 aatctaaaaa tatggaaaat gccaagaaat ttatcgattt tattatctct caagaagtac
     4081 aagatacact tggtacaacc actactaacc gtcctgttcg taaaaatgct aaaacaagcg
     4141 aaaacatgaa accaattgac aaaatcaaaa cactcactga agattatgat tatgtcatca
     4201 agaataaatc agatatcgtt aagaaataca acgaagtctt tacagatatc caatctaaac
     4261 agtaaaagag gttcactatg agtgagatcg aaattattaa cgccaaaaaa atctaccacg
     4321 atgtccctgt tattgagaat ttgaacatta caattccaaa aggaagtctc tttacccttc
     4381 ttggagcttc aggatgcggg aaaacgaccc ttcttcgtat gattgcaggt ttcaacagta
     4441 tcaatacttc gatgatacaa aaatcaataa tatggaatcc agcaaacgca atatcgggat
     4501 ggttttccaa aactacgcta ttttcccaca tttgactgtc cgagacaacg ttgcttttgg
     4561 tcttaagcaa aagaaggttc caaaagaaga attgattcaa cagaccaaca agtatcttga
     4621 actcatgcaa attgctcaat atgcggatcg aaagcccgat aaactcagtg gtggacaaca
     4681 acaacgtgtc accttggcat gcgccttagc ggttaatcca agtgttctcc tcatggacga
     4741 gccacttagt aatctggagg ccaaacttcg cttggatatg cgtcaagcca tccgagaaat
     4801 ccaacacgaa gtgggaatta caactgttta tgtaacccac gaccaagaag aagccatggc
     4861 tatttcagac caaattgctg ttatgaaaga tggggtgatc caacaaatcg gctgaccaaa
     4921 ataactctat cataaaccag ctaatgagtt tgtggcaacc tttatcggac gcacaaatat
     4981 tatccctgcc aatcttgaaa aacggagcga cggcgcttat atcgtctttt cagatggcta
     5041 tgcccttcga atgccagctc ttgatcaggt tgaggagcaa gctattcatg taagcattcg
     5101 tcccgaagag tttatcaaag ataaatctgg agatatcgaa ggaactatta gcgatagcgt
     5161 ctatcttgga ctaaatacgg agtatttcat tgagacaggt tttgcctcaa aaatttaagt
     5221 tagtgaagaa tcaacttttg aagaagaact acaaaaaggc aatcgtattc gtctacgaat
     5281 caatacgcaa aaattaaaca tcttttctgc agatggttcc caaaacctga taaaaggagt
     5341 caaccatgga atgtaaaaaa ctaaatattt ggacagcttc ctctttcttc atctttctta
     5401 cctatcttgt ctttctcgtt tatcctatcg ttaccgtgct caagcaagca cttatacatg
     5461 aaggacaatt ctcactagct aattttgtca ctttctttag taaagcctac tactctgaga
     5521 cactagtcaa cagtttcagg gtttccatta ccgctactgt cacttcctta gttgtaggaa
     5581 ccctattagc ttatctcttc tctatgtatg acttcaaggg gaagaaattt ctacaaatat
     5641 tgattatcat tgcttccatg tcagctcctt tcgtaggagc ctactcctgg gttctcttgc
     5701 tgggacgaaa tggggtcatc actaaatttt tgacaaatgc ccttcatctt ccagctatcg
     5761 atatttatgg attcaaagga attgtacttg tctttacact gcaactattc ccactggtat
     5821 ttctatatgt tgctggaaca atgaacagta ttgacaattc tctacttgaa gcagctgaaa
     5881 gcatggggtc cttcggattt aaacctatcg taacggttgt tttacctctc ctagttccaa
     5941 ccttactagc agctccttgc ttgtatttat gagagcattc tcagactttg gaacgcctat
     6001 gttgattggc gaaggatatc ggactttccc tgtcctgatt tatacccaat ttattagcga
     6061 ggttggagga aattctgctt ttgcaattat ggcgattatc attgccttgg caattttcct
     6121 tatccaaaaa cacattgcaa accgctacag tttcagcatg aatctgctcc atccaattga
     6181 gcctaaaaaa actacaaaag gaaaaatggc tgccatttat gcaacagtct acggaattat
     6241 ctttatctct gttttacctc aaatctactt aatttatacc tctttcctaa aaacatcagg
     6301 tatggtattt gttaaaggtt attctccaaa cagttacaag gtagctttca atcgtatggg
     6361 atctgctatt ttcaatacca ttcgtatccc tttgattgcc ttagttctag ttgttctatt
     6421 tgcgacattt atctcctacc tagccgttag aaaacggaat ttgtttacaa acttaattga
     6481 cagcctcagt atggtacctt atattgtacc aggaaccgtt ctagggattg ccttcatttc
     6541 ttccttcaat actggtctat ttggaagtgg atttcttatg attacaggga ctgctttcat
     6601 cttgattatg tctctatctg tcagaagatt accgtatact attcgctcat ctgttgctag
     6661 cttacaacaa atagcaccaa gtattgaaga agctgctgaa agcttaggaa gtagtcgtct
     6721 caatatcttt gctaagatta caactccaat gatgctatcg ggtattattt ctggagtcat
     6781 cttatcttgg gtcacaatga tttcaaaact ctctacttct atcctcctct acaatgtcaa
     6841 aacaagaaca atgactgtag ctatttatac agaggttctc agaggaaatt acggtgtagc
     6901 cgcagccttg tcaactatcc tgactgttct aacagtaggt tccttgctct tgtttatgaa
     6961 aatctctaaa agcaatagct ttacccttta gttttccaca tcaaaaacag ccgaaaggag
     7021 tgccctcggc tgttttttct tatcttgata ttcttatcaa atccctagct catggcaagc
     7081 aagtctagac tgattaaata gagccttctt ccatcttctc acgtcctagc tctcggtaac
     7141 tacggtcacc gacaacttca accctaaact gaccgccctc atattcaaga atcgtcacgc
     7201 taccattatc tagaccatgc ggatgcatgc cattaatcag ataaacaatg gttccaatag
     7261 tcattccatg gctgacaaca agggcgttac ctccaccttg atcttccatt tcttttgcaa
     7321 tcatttcaaa gccttccttg attcggccac tgagtttttc ccagccttca gcccaaccag
     7381 ctgtatcgac ctctaccaag ccctcagcca gttcagcata agacaattgg tgaacgtggt
     7441 ccacattaaa gatacgagga ataatgccca tgaaaagatc gccatcatag gctccatcaa
     7501 aactaccgaa acaccattct ctgatacgct tgtccatgcg ataagggatt ttcccctgca
     7561 agccaagctc ttcaaggata attcccatgg tctgaatggt acgaccagaa tcactcgaat
     7621 aagcgcgctc aaactgtaga tcagattctc gcaaaccgat tcctaactct tgaatccctc
     7681 gttcaccttc agcagttaag ggagtatcgc tccaaccttg cgcgcgacca atcgtgttaa
     7741 acatggtctt gccatgacgt accaaataca atcgtacttt taccattttc cgtcctccgt
     7801 ttgcttctat tatatcatga atgataaaat aaaagccacc catacaggcg acttttgaag
     7861 gagattatta tgaaaaagtt taggagttca ttaaataaag atattagatg aaaatcaaat
     7921 tcaaactaat tcaatgttat ctgtttcaaa taatattagg aggtctttat ttaatgatta
     7981 tagtatacac gtctaatctt aaatagaact taaaatttct cctattttct taatttttaa
     8041 aactatgaat tggtgctggg atttgtccac cgcgagagat gaagtcgaca gacgaagccc
     8101 cattaaccct cataacgggt gcagttccta atagaccacc aaactcaatc atatcgcctt
     8161 cttttccttt gggaatgata cgaacagctg ttgttttcat gttgataaca ccgattgctg
     8221 cttcatccgc aatcatagcc gcaatggttt cagcaggcgt atcttctggg atggcaatca
     8281 tatccaatcc aacagaacag atagccgtca tagcttctag tttttctaaa ttaagagagc
     8341 cattttgcac tgcagcaatc attccttcat cctcagaaac agggataaag gcaccagata
     8401 aaccaccgac ttggttgcag gccatcactc cacccttttt aacttggtcg ttcaagaggg
     8461 ccaaggcagc cgtcgttcca tgcgtgccaa ctgtttctag ccccatttcc tcaaggacac
     8521 gtgccacaga gtctccaacc gcaggggttg gtgccaaact caagtccaca ataccaaact
     8581 ccacacccag tctctcactg gccatttgac caaccaattg accgatacga gtgattttaa
     8641 aggcagtttt cttaactgtt tcggctacta catcaaagct ctgtccacga actttttcca
     8701 aagcacgttt caccacacca ggaccagaaa ctccgacatt gatgataaca tctgcttccc
     8761 caacaccatg aaaggcaccc gccataaatg gattgtcctc aacagcatta gcgaatacaa
     8821 ccaacttggc cgctcccata tctgaaagat ttgccgtttc cttgataatt cgtcccatat
     8881 ctgccacagc cgtcatatta ataccagact tggttgagcc gatattgact gacgagcaga
     8941 ccttatccgt ctcagtcaaa gcgcgaggaa tggaattgat gagaatctca tctccctttt
     9001 gataaccttt ttgtactacg gcagaaaaac caccaataaa gtccacacca atctctttcg
     9061 cagccttatc aagcgctttt gccagaacca cgtagtccgt cgcatctgtc gctgccccaa
     9121 tcagagaaat aggtgtcacc gatacacgct tattaacgat aggaattccc aactcagccg
     9181 caatttcatc accaacagct actaaattag ccgcctttgt cgtaattttt tgatagattt
     9241 tctccgcagc acgattgata tctggatcga tacagtccaa aagagaaatc cccatggtaa
     9301 tggttctaat atcgaagttt tgctcctcaa tcatggcgat ggtttcagta acttgtctaa
     9361 tatccatgat gacctcctag atattataca tagcttcgaa aatcgctgca ctctgaatat
     9421 tgatttttac attcaaagtt tgcccaaaag cttcaaattc attacgaaga taggtaaaat
     9481 cttgcttttc atcactagat acaacagcca tcatcgtaaa atattcatcc aagacagttt
     9541 gagagatatc gtcaatattc aatcctaatt ctgcaatttt accagaaaca cctgcaacaa
     9601 ttccagattt atctttacca acaacagtta taatggcttt cataagtaaa ctccaattct
     9661 tcttaaaata agaaacctta acattaaaca ggattctttt caaatagtat agcataattc
     9721 taacgaaaat actcaaaaac gcctgcttac gaagttgttc ttaagaaaaa aacaatttcg
     9781 taaacaagcg tctactatcc caacttatga tgagtgttcc cgctaggacc gaaatcctag
     9841 cggtagacca gagctagact aagagcacaa gactccatca tcataacact caacaaaatt
     9901 gatgatttta tactaattcg atgatcgcca ttggcgctgc atcaccacga cgtggttcag
     9961 ttttaaggat acgagtgtat ccaccgttac gttcagcata acgaggtgcg atttctgaga
    10021 acaatttttg aagtgctgta gtagaagtgt acttatcagt tgcttcatca tagttttcag
    10081 atgcgatttc attacgtacg aaagcagctg cttgacgacg tgcatgcaaa tcaccacgtt
    10141 tacctagagt aatcattttt tcaacagttt tacggatttc tttagcacga gcttcagttg
    10201 tcacgattga ttcgttgatc aaaaggtcag ttgtcaaatc gcgaagcatt gctttacgtt
    10261 gtgagctagt gcgtcctagt ttacggtaag ccatgtattc ctcctttatt tatcttttaa
    10321 tccaagaccc aaatcaatga gtttgagttt cacttcttcc aaactcttgc gtccaagatt
    10381 tcgtactttc atcatctctg cttcagattt ttctgtcaaa tcatgcacag tattgatacc
    10441 ggcacgtttt aaacagttgt atgaacgcac agacaagtcc agttcctcaa tcgtacgatc
    10501 taaaatacgg tcgtcagatt cagtatcagc ttctttcatc acttcagttg acttagcaat
    10561 ctcagtaaga tttgtaaaca aatcaagatg ttctgtcaaa atacgtgctg aaagccctaa
    10621 agcatcttct ggaataattg ttccatttgt caagatttca agggttaatt tgtcgaaacc
    10681 atcattgcta cctacacgag caggttccac ttgatagttg acttttgtaa ctggtgtata
    10741 aatagaatct acagcaagtg ttccaactgg tgcattatcc tttttatttt catcagcagg
    10801 tacatatcca cgaccactgt taacagtcat agtcgctttt agagaagaac cttcaccgat
    10861 tgtaaagaga taatgatctg gatttacaat ttcaatatcg ctatctgtca aaatgtcacc
    10921 agctgttact tcagcaggac cttcaacatc cagttcgatg attttttcgt cttcaacgta
    10981 cgatttcact gcaattcctt taatgttcag aatgatttgc atcacgtctt cacgaacacc
    11041 tggaactgtg tcaaactcat gtaacacacc atcaatgttg atagatgtca cagctgctcc
    11101 tggtagagaa gctagaagta cacgacgaag agagttacca agagttgtac cgtagccacg
    11161 ttcaagtggt tcgattacaa acttgccata atctttattt tcatcaattt ttgttatatt
    11221 tggtttttca aactcgatca tttagttact ccctcttaaa cgaaaagcag tgtaatgcga
    11281 tgattataca cggcgacgtt ttggaggacg agcaccattg tgtggcactg gagtcacatc
    11341 acgaattgct gttacttcaa gaccagcggc agcaagcgca cgaatagctg actcacgacc
    11401 agaacctgga ccttttacag taacttcaac tgatttaaga ccgtgttctt gtgcagattt
    11461 agcagcagct tcagaagcca tttgagcagc gaatggtgta gatttacgag aacctttgaa
    11521 accaagagca ccagctgatg accaagcaat tgcattacca tgcacatcag taatcataac
    11581 aatagtgtta ttaaatgtag cgtgaatatg agcaatacca gattcgatat tctttttcac
    11641 acgacgttta cgtgttggtt tagccaagac ttttacctcc tatattattt tttcttacca
    11701 gcaatcgcaa cagctttacc tttacgagtg cgagcgttgt ttttagtatt ttgtccacgg
    11761 acaggaagtc cacgacggtg acggatacca cggtatgaac cgatttccat caaacgtttg
    11821 atgttcaagt ttacttcacg acgaaggtca ccttcaactt tgattgcatc cacttcacga
    11881 cggatagcat cttcttgatc tgatgtaaga tcacgtacac gaacatcttc tgagattcca
    11941 gcagcagcca aaatcttctt agatgttgca agtccgatac cataaacata agtcaatgag
    12001 attactacgc gtttgtcatt tggaatatca actccagcaa tacgagccat gttttctcct
    12061 ttctatctta tccttgacgt tgtttgtgtt ttggatttgc tgggcaaatt accataacac
    12121 gaccattacg acgaataact ttacagtatt cgcaaattgg tttgaccgat ggtcttactt
    12181 tcatttctta tccctccaag tttttcgatt atttaaagcg gtaagtgata cgtccacgtg
    12241 tcaagtcata tggactcatt tcgacagtaa cacgatctcc cgctaaaata cgaatatagt
    12301 ttttacgaat tttaccagaa actgttgcta aaatctgatg tccattttca agttcaaccg
    12361 taaacattgc attcggcatt gtatcaacta ctttgccttc aacttcaatc acatcgtctt
    12421 ttgccacgca aaagcacctc cataaatttc gattcgatgc ctctagacac agagacaaca
    12481 attataagtc agactatctc agtataacat ttgtagcgga tttttgcaag tgtgaaaaac
    12541 gctttatttc aaatttgtca atactttttc aatatctgag aagacatcat tgatatcttg
    12601 attaccttcg atgtcatgaa ccaaaccttt ggcacggtag tgagcaatga ttggttctcc
    12661 ttgagcaata ttaacatcca aacgacgttt tactgtctca ggcttatcat cttcacgttg
    12721 gtagtagtct tcttctttat agtcaactgg tgggttaaag accttgtgga aagtttctcc
    12781 agttacgcgg tggatgatac ggccactcaa acgttccaag aggctgtcag ggttcacttc
    12841 aatattgata acaccttcta gttcaatgcc aagttcagcc aatgttttgt ccaaggcatg
    12901 agcttgttca attgtacgtg ggtaaccatc caataagaat cctgtttctt taatatcatc
    12961 ttgtgaaaga cgttctttta cgattccatt tgtaacttcg tcaggaacca attcaccctt
    13021 gtcaatatat gacttagcaa gaacacccat ttcagtttga tttaccattg cagcgcggaa
    13081 catatcacct gttgagatat gtgcaacatg gaattgttct acgatttttg ctgcttgagt
    13141 tcccttacct gcaccaggta agcccataat caaaagattc atgatttgat ctccttattt
    13201 tatttttaaa tagaagcaaa aagtcttttc acccctattt aaaaacaaaa tagaagaggg
    13261 gagatccaac tcttacaaat gtcagagttt aaacctccac tccctcagta tttactgatt
    13321 cagtaaatac ttttattctg ttttgtccat gaaaccaaca tacttacgtt tcaataggta
    13381 accttccaat tgcttgattc cttcgatacc tgtagagata atgatcaaga gacttgttcc
    13441 accaaaggca acaacatcag aaagaccaaa tacatcttta gctgcaatcg gtaaaatgga
    13501 aatcacacca aggaagaggg aaccaacagt tgcaagacga cgaagaagtt tagacatata
    13561 ttcttctgta cctttaccag gacgaactcc atggatatag gcaccactct tttgtaggct
    13621 ctctgctgct ttttcaggat taatctgtac aaacgtatag aagaatgtaa agagaataat
    13681 caacaaagca tacatggcaa taccagttgg agaagtagtt gccaacatct cttgtgctac
    13741 ccttacccaa gcccaatcat gacctgtggc actcaaaaac tgaagaatag ccgcaggcgc
    13801 tgcagtaatc gaactggcaa agataacagg gataactcca gcaggattta cctttaacgg
    13861 aaggtaagag ctagatggag caccttgtgc aaccttagta tattggatcg gaattttgta
    13921 ttctgcttgt tgaacataag ttgtaaagta aataatcaac aatacagtaa taatcaaaat
    13981 gattacgaaa atgatagatg aagtgatacg gctacttggg acgttcacaa agtagtccac
    14041 atagatgccc tgaatcatct ctggaattga ggaaacaatc ccggcaaaga taatcatgga
    14101 aacaccgttt ccgtatccct tatctgtaat ttgctcaccc aaccaagtga caatcatact
    14161 accagctgtt aagatgatac caatcgtcag aaaaacttgt ggagttaaag cagttttaat
    14221 caattgagct ccagccaagg tattaaaacc agctgtaatc ccgatagatt gcacaaaagc
    14281 gagaactaga gcaatataac gagtagcttg attcaatttt cttcgaccta cttccccttg
    14341 tttaccccac tctacaaact tgggtaaaat atccatttgc aagagttgga caacaataga
    14401 agcggtgata tagggactaa ctcctagggc aaaaatcgaa aagtttttta gggcattccc
    14461 cgacaccaag ctcaacatgt ttaagaagga taatccactt aaagcattca agctattggc
    14521 attcacacca ggaactgtaa tgctagttcc gatacgaaag accaaaacga taaaaattgt
    14581 aaataaaatt tttgatcgaa cctgcttgac tttaagagct tctcttaata atttaaaaaa
    14641 cataggtcac ctctcttaga tgacttctac tgaaccacct ttagcagtga tagcttcttc
    14701 agctgattta gagaatttag ctgctttcac agtcaatttc ttagtcaact caccgttacc
    14761 aagaatttta atacctgact tttcagcttt aacaattcct gcttcgataa gaacaactgg
    14821 agttacttca gcaccatctt caaagacgtt caattggtca aggttcacaa ttgcgtattc
    14881 tttagcgttg atgttagtga atccacgttt tggaagacga cggaacaatg gagtttgtcc
    14941 accttcaaaa ccaaggcgaa ctccgccacc gctacgagct ttttgacctt tttgaccacg
    15001 accagatgtt ttaccgttac ctgatgaagt accacgacca acgcggttac gtactttacg
    15061 agaaccttct gcaggtttca attcatgaag tttcattttt attttctcct cttttgtaaa
    15121 atgctagcgc cgataaggga gaaaaggttg tctcccccat caactcgcct atacgatgtc
    15181 atcatagatg actatatcta gttttagggg atggtacagt gcacatcccc taaaacttca
    15241 ttagtttact tcttcaactg ttactaagtg agatactgct gtgatcatac cacggatagc
    15301 agcgttatct tctttaataa cagagctgtt caatttgcca agtccaagtg ctacaacagt
    15361 tttacgttgt gatggaatgc gtccgattgg agacttagtc aaagtaattt taatttgagc
    15421 cattttatcc cctttcttat gccaaatcag aaactgaaat accacgaagg gcagcaattt
    15481 cttcagcgcg tttcaattgt ttcaaacctt caacagttgc acgaacaatg ttgattggag
    15541 tgttagaacc aagtgattta gatgtaatat ctgccacacc tgccaattcc acaacggcac
    15601 gaactgcacc accagcggca actccagaac cttctacagc aggtttcaac aatactttag
    15661 ctccaccgaa ttctgaaaga acttcgtgtg ggattgttgt tccaaccata ggaacttcga
    15721 tcaagttttt cttagcatca tctactgctt tacggattgc ttctggaact tcttgagctt
    15781 taccagtacc aaatcctacg cgaccattgt ggtcaccaac aacaacaaga gctgcgaaac
    15841 gaagacgacg tccaccttta acaacttttg taacacggtt gacagcaact acgcgttctt
    15901 ctaattcaac tgcattgtct ttaaatgcca ttttctagtg tcctcctatt agaatttcaa
    15961 tccgttttca cgagctgcat cagccaaagc tttcacacgt ccgtgatata gatatccacc
    16021 gcggtcgaac accacttctg aaataccttt agcgtttgca cgttctgcaa cgagtttacc
    16081 gacagcaacg gcttgttcag ttttagttcc ttttgaaact tctttatcaa gagttgaagc
    16141 acttgcgagc gttacacccg ctacgtcatc aatcacttga gcgtagatgc ctgtattaga
    16201 acggaatacg ttcaaacgtg ggcgatcagc agttccagag agttttccgc gaacgcgacg
    16261 gtggcgtttt tggcggagtt tgtttttatc tggttttgaa atcacagttt tcacctcttt
    16321 agttttaaat cgtgtgctat gcacaaagtt ggaaaatagg ttggtggttg atgatcaacc
    16381 actcaacatt atttacctgt tttaccttct ttacggcgaa cgaattcacc aacgtaacgg
    16441 atacctttac ctttatatgg ttctggtgaa cgaaggctac gtacgtaagc agctgtttga
    16501 ccaactactt cttttgaaat tccgctaaca acgattgttg ttgggtttgg aagttcaaaa
    16561 gtaattcctt ctggagcttc aacttcgtct ggatgagatt taccaacagc caaaacaagt
    16621 ttagatcctt gaagctgtgc acggtaacca accccacgca tttcaagttc tttcttgaat
    16681 ccttctgata caccaacaac catgttgttc aaaagggcac gagtagttcc gtggatagtt
    16741 ttcatttctt ttgaatcgtt tggacggtga agagttactt cagtaccatc cacacggatt
    16801 tcaatatctt ttgagaactc acgagtaagt tctcctttag gtccttttac agttacaacg
    16861 ttgtcattgt tagcgagttc aacaccagca ggcaacacga taactttatt accaatacgt
    16921 gacatgttta ttttctcctg ttaaattgtc aggccagaac ggccagtttt cacggggttc
    16981 agatacttat ttagttcaag agctgaactg aacacgctct aagaactgtg caaaatagat
    17041 aagttggctt gtttgtaaac aaacttctcc aacttcctaa ttttgctttg ttctttacga
    17101 gctttgtatc ttgattttac caaacgtaag caataacctc accaccaaca ttcttttggc
    17161 gtgcttcttt atcagtaagc aaaccttcag aagttgaaag gatggcaatt ccaagtccgt
    17221 taagaacttt tggaaggtct tcacgttttt tgtagacacg aagtcctggt ttagaaacac
    17281 gtttcaagtt agtgataact ttctcaccat ttggtccgta tttaagaaat acacggatga
    17341 cgccttgttt gtcatcttca atgatttcaa cgttttttac aaaaccttcg cgtttaagga
    17401 tttcagcaat cccttttttg atgtttgatg caggtacttc aagtacttcg tgtttagctt
    17461 ggttagcatt acgaatacga gttaggaagt ctgcgattgg gtcagtcata accattttgt
    17521 ttttctcctc ttactagtag tttgcaagtt gcacttgcta gttaatgatt gagctgggct
    17581 cagatagtat tgacacattc aaatgagaga actcttattt gaacacgagc tacaacctgt
    17641 gcaaaaaaga taaatttgtt ttggagcatc gctccctcac caaatttcct attttcgctg
    17701 tggttgttac gctctttgta tcatgatatt accaagatgc ttttgttaca ccaggaattt
    17761 gacctttatg cgcaagttcg cgaaaagcga tacgactcag accaaatttg cggtaaactg
    17821 aatgtgggcg ccccgtaact ctacaacgat tatgtaaacg agtcggtgag gcgttgcgag
    17881 gtaatttaga taaaccttcg tagtcccctg ccgcctttaa tgcagcacgt ttttcagcat
    17941 aacggtcaac aattttttgg cgtttagcct ctctagctac cattgatttt ttagccatta
    18001 gatttacctc ctatattatt ttgcaaaagg cattccaagg cctgtaagca atgcacgtga
    18061 ctcttcgtca gtgttagcag ttgttacgat aacgatgtca agaccacgag ttttgtcaac
    18121 gtcatcgaag ttgatttctg ggaagattaa ttgttctttc acaccaagtg tgtagttccc
    18181 gcgtccatca aatgattttg ttggaacacc gtggaagtca cgtacacgtg gaagtgaaac
    18241 tgataccaat ttatccaaga attcgtacat acgttcacca cgaagggtaa cttttgcacc
    18301 gatcgcaaca ccttcacgaa gacggaagcc ggcgattgat tttttagctt tagtgataag
    18361 tggtttttga cctgagataa gtgccaattc ttcagcagct ttttcaaggc ttttagcgtt
    18421 tgatacagct tcaccaacac ccatgttcaa aacaatctta tctactttag gcacagccat
    18481 cactgatgag tagttgaatt gttctgtcaa agcaggaact acttcattaa gatatttttc
    18541 ttttaaacga tttgccatta tacttctcct ttccttcgtg attaatcaag cacttcgcct
    18601 gattttttgt tgtagcgaac ttttttaccg tctacaaatt tgtaaccaac acgaccagct
    18661 acaccatttt tgtccaaaac ttgaacgttt gatacgtgga tagctgcttc tttctcgatg
    18721 ataccacctt gaggaagctc gttagttgga cgttggtgtt tcttaacaat gttaacacct
    18781 tcaacgataa ctttgtttac ttttggaagg gcagtaagga caacagcttc tgttccctta
    18841 tctttaccag cgattacgcg aactttgtcg ccttttttta caaacattag gtttctcctt
    18901 gatttttctt acgcccataa gggcacccta gcttgaagct aggggactag tttgttccta
    18961 aaaattaaag tacttctgga gcaagtgaca cgatcttcat gaagccacct tcacgcaatt
    19021 cacgtgcaac tgggccaaag atacgtgttc cgcgaggagt tttgtcttca cggatgataa
    19081 ctgctgcgtt ttcgtcaaat ttgatgtatg aaccatcagc acgacgagca cctgatttag
    19141 tacgaacgat aactgcttta acaacgtcac cttttttaac cgcaccacca ggagtagctt
    19201 gttttacaga tgccacgata acatcaccga tgtttgcaaa tttacgtcct gaaccaccaa
    19261 gaactttgat agtcaagatt tcgcgagcac cgctgttgtc tgcgactttc aaacgagttt
    19321 ctgtttgaat catttcagtt ttctcctttc aggtttgatt agatgatgac cgcttcttca
    19381 acaacttcta caagacggaa acgttttgta gctgaaagcg ggcgagtttc catgatacgt
    19441 acgatatcgc cttctttggc aacattgttt tcatcatgag ctttgtattt tttagagtag
    19501 ttaatacgtt taccatagac tgggtggtta cgttttgttt caactacaac tgtgattgtc
    19561 ttgtccattt tgtcagatac aacacgtcca acaagaactt tacgattatt gcgttccatt
    19621 gaaatttctc cttccctagt ctattatttc gcttcagatt gaactgtttt gatacgagcg
    19681 atttgttttt taacttcttt caagcgaact gtttgttcca attgaccagt agcagcttgg
    19741 aaacgaagtt caaacaattc ttttttcaat tcgttttcgc gcttcgcgag ttcttcttga
    19801 gaaagaccac gaagttcttt aacaaattct tttacttcat taagtttcat gccttctcct
    19861 tattctgctt cacgttttac gaatttacat ttaactggca atttgtggct agcaagtcga
    19921 agcgcttcac gtgcaatctc ttcagataca ccagcgattt cgaacatcac tttaccacgt
    19981 ttaactggtg ctacccaacc ttcaggtgcc cctttaccag atcccatacg cacaccgata
    20041 gctttagcag tgtatgattt gtgtgggaag attttaatcc aaactttacc accacgtttc
    20101 atgtaacgag tcatggcgat acgagcagct tcgatttggc ggttagtgat ccagtggcta
    20161 gttgtagctt gaagaccgta ttcaccgaat gctacttctt ttccaccttt tgcttcaccg
    20221 cgcatttttc cacggaattc acgacggtgt ttaacacgtt taggtactaa cattggttat
    20281 ttacctcctt tagtgttttt acgagctgga agaacttcac cacggtagat ccatacttta
    20341 acaccaagtt taccgtatgt agtatctgct tcttcccaag cgtaatcgat atctgcacga
    20401 agtgtgtgaa gcggaacagt tccttcagag tatccttcag cacgggcgat atctgcaccg
    20461 ttcaaacgac ctgatacttg agttttgatt cctttagctc cagcacgcat tgcacgttgg
    20521 attgcttgtt tttgtgcacg acggaaagca acacgttgct ccaattgacg agcaattcct
    20581 tcacctacaa ggtgagcatc caaatcaggt tgtttgattt cgatgatgtt gatgtgtact
    20641 tgttttccag tcaatttgtt aagttttgca cggagtgcat caacgttagc accaccttta
    20701 ccgataacca tacctggttt agcagtgtga agtgaaacgt taactttgtt tactgcgcgt
    20761 tcgatttcaa tagttgaaac tgctgcgtca gcaagttctt tttgaacgaa tttacggatt
    20821 gcaagatctt catgaaggta atccgcgtat tctttttcag cataccattt ggcatcccaa
    20881 tcacggatga tgccgacacg cataccaatt ggatgtactt tttgacccac gattttacct
    20941 ccttattttt ctgcaacagc tacagtgatg tgagctgtac gtttgttgat tggtgaagct
    21001 gaacctttcg cacgtggacg gaaacgtttc atagttggtc cttcgtttgc gaatgcttca
    21061 gatactacca agttagcttt atccaaacca aagttgtttt cagcgttagc tacagctgag
    21121 ttcaaaactt tcaagatgat ttcagcagct ttgtttggag tgaatgtcaa gattgcgatt
    21181 gcatcggcta cgcttttacc acggatgtta tcaagaacaa gacgtgattt acgaggtgaa
    21241 acacgtactg tacgagccat tgctttagct gaagtaattt ctgccattta tgttctcctt
    21301 attttctacg tgttttcttg tcgtctgcag cgtgaccttt gtaagtacga gttggtgcaa
    21361 attcaccaag tttgtggcct accatgtctt cttggatgta aacaggtacg tgtttacgtc
    21421 cgtcataaac tgcaatagtg taaccaatga aacttgggaa gatcgttgaa cgacgtgacc
    21481 aagttttaat aacttttttc ttttcgtcgt tagcttgagc ttcaactttt ttcatcaaat
    21541 gctcatcgac gaaaggtcct tttttaagac tgcgtcccat ttttatattt tctcctttaa
    21601 atgttgtacc acagcggctt gcactcctat ggagcgctac cgagctggcg gatttactag
    21661 ttgcttaagc gactagtcta atattatttc tcgttgcgac gacgaacgat aagtttgtca
    21721 gatttcgctt tcttgttacg agttttaaga ccaagagcag gtttgcccca tggagtagat
    21781 ggtgctttac gaccaactgg tgctttacct tcaccaccac cgtgtgggtg atcgttaggg
    21841 ttcattacag aaccacgaac tgttgggcgg atacctttcc aacagctacg tcctgcttta
    21901 ccaaggttta caagtccatg ttgttcgttt ccgacaacac caactgtagc acggcaagtt
    21961 ccaagaatca tacgaacttc acctgattga agccgaacaa gaacatattt accttcagaa
    22021 cccaatactt gagcagatgc accagcagca cgtaccaatt caccaccacg acctggtttc
    22081 aactcgatgt tgtgaatcaa agtaccaact gggatgttag caagtggaag agcgtttccg
    22141 actttgatat ctgcttctgg acctgaaacg atacgttgac ctacttcaag accttttgga
    22201 gcgatgatgt atgctttcac accgtcagtg tagtgtacaa gagcgatgtt tgcagaacgg
    22261 tttggatcgt actcgattgt tttaacaact gcttcaacgt tgtctttatt acgtttgaag
    22321 tcaaccaaac ggtagaaacg tttgtgtcca ccaccttggt gacgaactgt gatacgaccg
    22381 ttgttgttac gaccagcctt gctcttcaat gcaacaagca atgatttttc aggagtgctt
    22441 gttgtgattt cagcgaaatc caaagaagtc atattacggc gaccgtttgt tgttggttta
    22501 taaacacgaa ttcccacgat atttcctcct tagattattc agcttcagca gcaaacaact
    22561 cgattgcttt agaatcagct gtaagtgtga tgatagcttt tttagttttg ttagtaaaac
    22621 cagtgtaacg tccaacacgt ttagcttttg gttttacgtt gattgtgtta acattggcaa
    22681 ctttaacacc ttcgaaagca gcttcaacag cttgcttgat caaaagtttg tgtgcacgag
    22741 tgtcaacttc aaatacatat ttccctgctt caagttgagc cattgagctt tcagtgatga
    22801 caggtttttt gataacatca tacaaattca ttatgcaaga acctcctcga ttttagagat
    22861 agctgcttgt gtgacaagaa gtttgtcgct atttgcgatg tcaagaacac ttgcagttgt
    22921 agcagttgca actttcacgt ttggaaggtt acgagctgaa agagctgcga attcatttcc
    22981 ttcttcaagg ataacaagaa ctttagaatc gatgctcaat gctgcaagaa cttttgcaaa
    23041 ttcagcagtt tttggagctg taaatgaaag agcgtctaca gctacgaatt tgttttcagc
    23101 aactttttca gagtaaactg atttaagagc taggcgacga actttttgtg gaagtttgta
    23161 gccgtatgaa cgtggagttg gtccgaagac aacaccacca ccacgccatt gtggtgagcg
    23221 gatagaacct tgacgagcac gtccagttcc tttttgacgc catggtttgc gtccaccacc
    23281 tgatactgca gagcggtttt taacagcgtg tgttccttga cgaaggcttg cgcgttggct
    23341 gatgattaca tcaaacacaa ctgattcatt tggttcgata ccaaatactg catcgctaag
    23401 aacaacttgg ccagcttctt taccagtttg gtcaaataat gttacgtttg ccattgtgac
    23461 tgatttcccc tttctttatt atttaccagc tttaactgct gatttgatag tgataagaga
    23521 tttcttagca cctggtacgt tacctttgat aaggataacg ttcttttctg gaacaacttg
    23581 tacaacttca aggttttgaa ttgttacgcg gtcgccaccc atacgccctg caaggttttt
    23641 acctttgaat acgcggttag gtgcaacagg tcccatagaa cctggacgac ggtggtaacg
    23701 agaaccgtga gccattggtc cacgtgattg tccgtggcgt ttgataacac cttggaaacc
    23761 tttaccttta gaagtacccg ttacgtcaac aacatctcca gctgcgaatg tttcaactgt
    23821 gatttcagcg ccaacttcca agccttcaac gtttttgaat tcacgaatga agcgcttagg
    23881 agccgtgtta gctttcgcta catgtccttt agcaggtttg ttgctcaata cttcgcgttt
    23941 gtcatcgaaa ccaacttgga tagcgttgta tccgtctgtt tcaacagttt taacttgaag
    24001 aacaacgttt ggagttgctt caataactgt tacagggatc aattcgccag cttcagtgaa
    24061 gatttgagtc attcccactt ttttccctaa gattcctttt gtcatgagaa aatagttcct
    24121 tttctatatt ttttattcaa aaagttttta acgagcgttt tttatgctca agtctaagat
    24181 acaaagggcg tcaaactcaa cgtgaaaata ggaaactgac gcagtgtcta gcagacacta
    24241 ggaagtttat ctttttcaca ccgagtttag tccgtgttca attagattga aacaccagcc
    24301 tctgctcttt tatattttag attaaagttt gatttctacg tttacaccac ttggaagatc
    24361 caatttcatc aaggcatcaa ctgttttttg agttgggtta acgatatcga tcaaacgttt
    24421 gtgtgtacgc atttcaaatt gttcgcgaga gtctttgtat ttgtgagtcg cacgaatgat
    24481 tgtgtagagg ctacgttcag ttggaagtgg gattggaccc gcaacttgtg cacctgtacg
    24541 agtagctgat tctacgattt ttgcagccgc tgtgtcaagc gtacggtgtt cgtaagcttt
    24601 caaacggata cggatttttt tgtttgccat ctttttctcc ttttcgtcta tttaagataa
    24661 taggctagct ccacaagaaa accgacgcgg tgttgcgtgg caatgcaacc gagcgtgtcg
    24721 caacctcttg catcaaaact aaggctgtaa tttacagcac cataatagaa taacacaaag
    24781 cccctgcgat tgcaagggat ttgttgctgt tttttcgttt ttttgggatg aaactgtttt
    24841 cctacttttt ctttctaaaa ttagggattt tcttctatat ttcttctata cataagttaa
    24901 gtcctcttga catcaaattt atcttctgat tggtccacta agatatccgc cttagactca
    24961 gtttctttat agtatcgcag atactgctcc cgtctcatct gatggctagc caatataaag
    25021 gatgcatcgc gatttctcac agtcgtatct ctagcaaggc gtcgctttaa ttcggtctcc
    25081 tcatccgtgt agaaacagat ggttttttca aagagttcct tgggtagaaa gccaacagac
    25141 atcccttcga caatcaaaat tggtttggct ccagacaaga cctcactagc cttccaaggt
    25201 tcttcaattg tcaagacatc catacccgcc tgcaaggcaa ggatatctct ctgcaaactc
    25261 tccagttcat gcgccactgg cagactggct gtcacctttt gattcggcgc gtccttgggt
    25321 actaccagat ggcgtcctga ggtgatataa ggatctgtct ctagcaaatt tactgtagta
    25381 gaatctaaag cttggtacaa ttcctgtgca aaggttgatt tacctgaagc tccatgaccg
    25441 tatattccca gtgtcctgac tttccccgtc tcgatctctg agactagttg gtctactaag
    25501 tcctttttct tcattctctc ttcacctgtt catagctttc ttttccgtca ttgatcttgt
    25561 cccaaatcac tacttgccca cttttgagcg atttttgcac atcgataatt cgttggttgg
    25621 acgaacctcg aaactggagc atgagatttc tcttagttcg atcgtatcgt ccatcgacaa
    25681 gaatgtcaat caatgataag agttccagtt tatctggagt ttccaacatc atttcttccc
    25741 aagtgtagcc cgtccaggac caaatgtcct tgtctggcaa ttcctttcgg atgcgtttaa
    25801 ctagaggcaa gagaatgcca gtattgagaa aaggctcccc tcccagcaaa gtcaagcctt
    25861 gaacataggg ttgggcaagg tctgccataa tctgctcttc taattctgct gtatagggaa
    25921 tgccagcatt aaaagaccaa gtcgcaacat tataacatcc ctcgcagtga aacatacagc
    25981 ctgatacata gagagagttg cgcacgcctt cgccgtccac aaagttaaag gccttgtagt
    26041 caatgatacg accttgacta agttcctcgc ttttccattc ttgtggtttt ggattattca
    26101 ttcgctacct ctatccaata acgctcgact ccattgcgag catcctcaaa tattccacca
    26161 tttgctagaa tgactgctct gctagcagga ttattcacac tacaggtcac cagagctttc
    26221 ttgatgttct tttccttagc aacttgcaag ccctgacgga gagtctcttt tgcataaccc
    26281 ttgcctcttt cagatggacg aatggagtag ccaatgtggc cagcataatt cagtaacccc
    26341 tcattcagtc tcaatcgcag attcaaaaat cctagagcac aacctgattc accaaacaat
    26401 acgaactgta tcgatggaac gcgattttca ggtagccata ttcccatttc tttattacgg
    26461 ttaccttcta gccactcctc gtaagaaaaa tcctcaacat cccaaaatcc tccatcatgg
    26521 gctgattggc tcttttcaaa ctctgtcatc atatctaaaa cagctttctt atccgctaat
    26581 cttggtctgc gtaattccat ccctacctcc cactatgaga aaagcgagag ctggctctca
    26641 cttttatttt ttcttgttct tgtttaaaaa ttgttctctg aagctaagca agcgttcttt
    26701 cttaccagct ccacctttag agtgct
//
LOCUS       DAVDHZ010000028        25889 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000028 DAVDHZ010000000
VERSION     DAVDHZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.029"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(751..1810)
                     /locus_tag="VUR46_001436"
                     /pseudo
     CDS             complement(751..1810)
                     /locus_tag="VUR46_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2613..2825)
                     /locus_tag="VUR46_001437"
     CDS             complement(2613..2825)
                     /locus_tag="VUR46_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456845.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEVLIAISGANLLLSFLKKLQTK"
     gene            complement(2833..3207)
                     /locus_tag="VUR46_001438"
     CDS             complement(2833..3207)
                     /locus_tag="VUR46_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HET5456846.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGGAIYIPKWAITGAITGAAYAA
                     LVAAGGGGLQLVLASYGLRSALVAGIIKGLGVLGIHIGNAFANTVIRSIASAGIGAGA
                     DWIFTNIIDGWDGRRDNQLRIG"
     gene            3964..4284
                     /locus_tag="VUR46_001439"
     CDS             3964..4284
                     /locus_tag="VUR46_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5456847.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSILSHLEKEVEIYYQ
                     AKER"
     gene            complement(4336..4923)
                     /locus_tag="VUR46_001440"
     CDS             complement(4336..4923)
                     /locus_tag="VUR46_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET5456848.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            5165..5836
                     /gene="sdaAB"
                     /locus_tag="VUR46_001441"
     CDS             5165..5836
                     /gene="sdaAB"
                     /locus_tag="VUR46_001441"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET5456849.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPDIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNVHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            5845..6717
                     /gene="sdaAA"
                     /locus_tag="VUR46_001442"
     CDS             5845..6717
                     /gene="sdaAA"
                     /locus_tag="VUR46_001442"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET5456850.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            6739..7371
                     /locus_tag="VUR46_001443"
     CDS             6739..7371
                     /locus_tag="VUR46_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5456851.1"
                     /translation="MISITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLIYQPDYIAHKPLEVLAYFQ"
     gene            7421..7648
                     /locus_tag="VUR46_001444"
     CDS             7421..7648
                     /locus_tag="VUR46_001444"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456852.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIYGKATLTWFEEIFEEYKSLHNKTHNIRC"
     gene            7859..8095
                     /locus_tag="VUR46_001445"
                     /pseudo
     CDS             7859..8095
                     /locus_tag="VUR46_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8138..9988)
                     /locus_tag="VUR46_001446"
     CDS             complement(8138..9988)
                     /locus_tag="VUR46_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET5456853.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIAFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRISWQLIYSRRKKGSGDGEHRLTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKHHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTIHIE"
     gene            complement(10030..11187)
                     /locus_tag="VUR46_001447"
     CDS             complement(10030..11187)
                     /locus_tag="VUR46_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5456854.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            11245..12411
                     /locus_tag="VUR46_001448"
     CDS             11245..12411
                     /locus_tag="VUR46_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET5456855.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVMLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQSSSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            12550..12876
                     /locus_tag="VUR46_001449"
     CDS             12550..12876
                     /locus_tag="VUR46_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET5456856.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            12863..13456
                     /locus_tag="VUR46_001450"
     CDS             12863..13456
                     /locus_tag="VUR46_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET5456857.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            13449..14360
                     /locus_tag="VUR46_001451"
     CDS             13449..14360
                     /locus_tag="VUR46_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET5456858.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            14423..15487
                     /locus_tag="VUR46_001452"
     CDS             14423..15487
                     /locus_tag="VUR46_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456859.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(15686..16521)
                     /locus_tag="VUR46_001453"
                     /pseudo
     CDS             complement(15686..16521)
                     /locus_tag="VUR46_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
     gene            complement(16796..17782)
                     /locus_tag="VUR46_001454"
     CDS             complement(16796..17782)
                     /locus_tag="VUR46_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET5456860.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(18054..19529)
                     /locus_tag="VUR46_001455"
     CDS             complement(18054..19529)
                     /locus_tag="VUR46_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET5456861.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(19787..20710)
                     /locus_tag="VUR46_001456"
     CDS             complement(19787..20710)
                     /locus_tag="VUR46_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5456862.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(20724..21653)
                     /locus_tag="VUR46_001457"
     CDS             complement(20724..21653)
                     /locus_tag="VUR46_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5456863.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            22185..22409
                     /locus_tag="VUR46_001458"
                     /pseudo
     CDS             22185..22409
                     /locus_tag="VUR46_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22513..22668)
                     /locus_tag="VUR46_001459"
                     /pseudo
     CDS             complement(22513..22668)
                     /locus_tag="VUR46_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(22855..23466)
                     /gene="rpsD"
                     /locus_tag="VUR46_001460"
     CDS             complement(22855..23466)
                     /gene="rpsD"
                     /locus_tag="VUR46_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET5456864.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(23661..24713)
                     /locus_tag="VUR46_001461"
     CDS             complement(23661..24713)
                     /locus_tag="VUR46_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET5456865.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(24710..25408)
                     /locus_tag="VUR46_001462"
     CDS             complement(24710..25408)
                     /locus_tag="VUR46_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456866.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(25575..>25889)
                     /locus_tag="VUR46_001463"
     CDS             complement(25575..>25889)
                     /locus_tag="VUR46_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5456867.1"
                     /translation="INVKETSDTANDQMKKSGMKPETPAPGTTNSMPADTMASSTNTM
                     AGENMAASANKMSDTMMSDDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKE
                     EN"
BASE COUNT         7941 a         5450 c         4574 g         7924 t
ORIGIN      
        1 cccccgtaaa tatttgtcaa gtgttttata ttacattttt gttacaaatt tctatatcat
       61 aagcttctac tccaaaaaat agataaagat actacttttg cccatttcga ttctcttttt
      121 aaacatagca tcatcttcct tcattcctat aaaaacattt ccgatgagag agcttgtttt
      181 ttaatttcgt taaacaacaa aaaacgcaag cttaagcctg cggacaatct ttatagccat
      241 ttcatttctt tcacatctgt tttacgaact ttagcatatt tcttagcgct tgtaaaatgt
      301 agagtaactg gtttaaatac tccgcttttg tctcttcgta aacctaaaac ttcggatctt
      361 ttatttctat cctcaaaaaa tatgacgtcc aatttcatag tatttttaga taaatcctta
      421 gccaagatgc aacaacttat tattttagaa tagaaaatat cactgataaa ctcatataaa
      481 gatatccttg cacattgcat cacctaatcc tgcgctactt gcccataatc ctttaatgtt
      541 tctactaaaa ttattccaat ctcccccatc aagatagctt atttatccta gacaatgcct
      601 actgcaacag tataaataaa agtcatccgc catcttttct ggcaatcata tgggtagcct
      661 aatgatattt ctagttactc aaaaatatct agctatacta gagttatttc taatccctag
      721 gacgcttgtt aatccaaata taacaaattt tcacccctta ataggactct ttctggaaaa
      781 aatataaggt ctatctttat aaaaaaatct atcatattgg gatggcatgc atctggaatt
      841 taaacaagct atagattcat ttataactac tatttgttta gaggcaacag catcttgtat
      901 accgccctcg aaagaaccat cttgtaattc cgaaatattt ttatttaaat attgttttga
      961 caagtctctc aatgcttcat tatcgtaaat gattcccaaa aatccaacct tatatagtaa
     1021 ataatttaaa cttacaaagt aattgaatcc catagtatat ttttctttat aaagcaaagg
     1081 taaaacttta taaaaaatat ctaagtcaac ctcactctga ttctgaagca agtaggagtc
     1141 aagcaaattt tcaaaaatag ctaacaatat gattggtgta aggtttttgt attcacatgt
     1201 caagtattct gagtatcgtg cagatgatat ttcttttata taactttttg aaagcaagat
     1261 tttttcaaat tcatcatcta ttattaatct tctatttcca atccaagcgg tattgctacc
     1321 caaataagat tgtacaaata gcaatatgta agaaaacatg aacgtaaata ctgaaagagg
     1381 tagaattcta tgcgtaaaaa aaatagacga taatggtagc caggagtaaa gctatctctc
     1441 gtgacaatcg aattcttttc agcatctttt ttaacagccc gtaaggttgt ccttggcaat
     1501 attcttgaac taaattaatc ggaatgacat ctctcaccat ttctggaaag tagagtaagt
     1561 ttataggttg aaatctccag ctcccatcat aagtaaatgg atatagaacc aaatacttaa
     1621 aagatttttt tcttataaac ttaattatca caatatgaat gactgttcca atgaagtata
     1681 ttaaatataa aagtaaaacc gccatcaata tacttacaaa aatccccttg gaatcaatca
     1741 atggaaaata aaatattgca actagaagcg aataaagtcc cactaataaa tatttctgat
     1801 catcattcat ttaaaatacc atattattta ctaagaatat atcaatataa cagagcaatt
     1861 ctgtaagtca atatttgata aagcaaagtt ttaaaccctt ccccagacgt tagcttttat
     1921 tcaacccact acagttgaca aggagcccaa attattgata aaaactttag tcatcatcgt
     1981 ctctataaaa atattttcta tacactcttg ataataccaa aattaatgcc aatatcatac
     2041 caagagctat aataataaaa taaatctaat aaatttcacc aattcctgca aaaaaatgtt
     2101 tcatagctat agttttacgt ccataaatat ccatcaaatt taccgtctac gatatctaaa
     2161 ccatatgcaa tggctcctcc taatgagaag acttcagcaa cagtagccgc aatattaaga
     2221 gcattagtaa tagttgccat actaactcca ccaatatatc ttgttatagc acttagttac
     2281 ctagataaga tatcctttag cttgcttcca aaatttaagt ctgcacctat aatatgagtt
     2341 catattagta ctgctaaatc ctatctatag taatgtcaaa cacctaaata aagtcatctc
     2401 tccaattcat tcaagaaatg aagaaaggca aaaaatcttt aaaataagaa aaatgcatat
     2461 tatcaggtgt tcaaaaatat tgatgatata cgttatataa tagaaaaatt tactcaattt
     2521 cattttcaaa ttaagttttt tcccagcctc atttttaatt tatatcttca atagaatcta
     2581 atgaccgagc tactgtatta cacagattaa tattatttag tctgtaattt ttttaaaaaa
     2641 cttaatagta aatttgctcc gcttattgct atcaatactt caattggtaa aaaatagtaa
     2701 ttccaaataa aatgagaaat cagcaatgat agaaaaataa caatatcaat tttcctgttg
     2761 ttgacatact ctgtaatttt atggtacagg aatgcaacaa taactgaaat taaaacaatc
     2821 aacataagat tattaaccta ttctcaattg attatcacgt cgcccatccc agccatcaat
     2881 aatattggta aaaatccaat cagctccagc accaattcca gcagatgcaa tacttctaat
     2941 aacagtattt gcaaaagcat ttccaatatg aattcctaat actcctaaac ctttaataat
     3001 cccagctacc agtgcggagc gtaatccata agatgcaaga actagttgaa ggcctccacc
     3061 tcctgctgct actaatgctg catatgctgc accagtaatg gctcctgtaa ttgcccactt
     3121 gggtatatat atagcccccc ccccatcaag gtacatcatc tcttcttcat caatcacaac
     3181 ataattattt ggtaatacaa gttccatttg ttttctcctt tttattaagc atggttagga
     3241 tggtttccta acaagtgatc gcaggctttg tttagttacc taaattagac ttccttcctt
     3301 tatcttattt taaatattta aaaccagtta ctgcttgaag cttaacagtt tacttaattc
     3361 aaataacagc taatcactga ttccctgatt ttatcaaata tactaataac aacaattgtg
     3421 atacgatcat cattataaga acaacattta acgaatcaaa gtttttccga gataataata
     3481 aagcaacagc aagcagtatt attactaaag attgaataac tactattact cttaacattt
     3541 tatcctccac taacaactca agctccctta cattatatcg accagcccca tggaaagatt
     3601 atagccagac taatcaatga tataatacat actagaatac aaaatatttt tttattcata
     3661 ctttttctcc tatctttatt ttctacctac atagtacctc ttattaagct catttcaaaa
     3721 ttacgttaac ttttttcacg aaaaggagaa aattatgcgt tatgatcatg gatagcgctt
     3781 tcaaattttt aaactcctat cccatccttt tatctatatt atgagcgaaa atataataac
     3841 tgtcaagtaa ctaaagtgaa ttttataaaa aaattacaag ccaaatttgt aaagtttaca
     3901 ctaagccgct agggcaatcg tctatcagaa tgtccgttta tttgtcaata atccgagaaa
     3961 atcttgcaac gcttagaagt ctataaaaac tatcaacatt tatatgactt gcgaatagca
     4021 atcctgctca acctttccac actctatcta tacaatcaag ataaaaacat gtgtaagcaa
     4081 atctgctaca ctttactaga ggacgccaag aataagaaaa gctacgatag gcttgctatc
     4141 tgctatgtcc gtattgggat ttgtacagat aatgctaaac ttatccaaaa agggttctcc
     4201 cttctggagc taaccgagga aacttctata ctgtctcatc tcgaaaaaga agtagagatc
     4261 tattaccaag cgaaggaaag ataaaaaagc cgagggattt cctcgactct ttacatatta
     4321 tttgttcgtt agttcttaat accagccatt gttaagccag aagtttttag cagcagtcca
     4381 tgaaccgtaa cgtcctgcaa cgtaggcatc tgctacacgt tcttggtttt cagctgagta
     4441 gtcaccgttc aggtatgaat ctgttaattg gtaacgtccg atataacgtc catttgtagc
     4501 tgtatagcta ccacctgatt ctttttgagc gatccattct ttggcttctg cttcagatcc
     4561 gcttacagtt gaaacaactg tttcacttac tactggagtt tctgctactg gagctgaaac
     4621 agtttcatct tgagcggctg gtgccgcata agtagctggc gctggtgttg caacaggcgc
     4681 tacagggcca tcgataacca actcttgacc aacataaatc aaatgaatgt tatcaatgtg
     4741 gttgttttct gccaattttt caactgttgt gttgtgagtt tcagcgattt ctgaaagtgt
     4801 atcaccttct ttaacagtgt aagttgatga ttcttgagca gatacaaatg atggagcaaa
     4861 tactgcaaac aaggcagcta ctcctgcaag agttgcttta atctttttag ttattgattt
     4921 catattcgaa aattctcctt ctttctatag ttctatcata ccctttaaat attaccgttt
     4981 cttgacactt ttatgtagaa atattacaaa attatttttt atttccctag ataaggtgtt
     5041 ttttgtcata aaagatacta tttttatgct atttgaggta ttagaaaggt tttcatccac
     5101 aattaaagtc aagaccctca ttctttgata taatagagat aagaattttt ataaggggaa
     5161 actgatgaaa tcacttcgtt ttcaatctgt ctttgatatc atcggaccag ttatgattgg
     5221 cccatctagt agccataccg ctggtgctgt tcgtattggg aagattgtct cttccatttt
     5281 tgatgatact ccgacagaag ttgaattcca actttttaac tcatttgcca agacctatcg
     5341 tggtcacgga acagacctag cccttgttgc aggtatttta ggcatggata cagatgatcc
     5401 tgacattcca aacagtctgg agattgccca caagcgtggt atcaagattg tctggaccat
     5461 tcagaaagac agcaatgccc ctcaccccaa caccactaaa attaccgtca aaaatgtcca
     5521 caagaccatc agcgtgactg gtatttctat cggtggagga aatattcagg taaccgaact
     5581 caatggtttt gccgtctctc tcaatatgaa tacaccaact atcatcatcg ttcatcaaga
     5641 tattccaggc atgattgccc tcgtaacaga ggcgctttcc cgctatggta tcaatatcgc
     5701 ccagatgaat gtcactcgtg aaaaagctgg tgaaaaagcc attatgatta tcgaagttga
     5761 cagtcgcaac tgtgatgagg ctatcgaaga aattcgaaaa atccctcatc tccacaatgt
     5821 caatttcttt aaataggagg aagcatgttt tattctatca aagaattggt cgagcaagca
     5881 gatctggact ttcaaggaaa tgtcgcagaa ctcatgatta caacagagtt tgaattgacc
     5941 ggtcgcgaac gtgaagaagt cttccttctc atggaacgca atctggaagt catgaaagcc
     6001 tctgtccaac ttggcctcaa tgaaaataaa tctcgtagtg gcctgacagg tggagatgct
     6061 gccaaattgg accactacat caaaaacgga aaaactctgt cagattacac gattctctct
     6121 gctgcccgaa atgctatcgc agtcaatgaa cacaatgcta aaatgggctt ggtctgcgct
     6181 actcctaccg caggaagtgc cggttgtctc ccttccgttc tcactgctgc tattgaaaaa
     6241 ttagacctca gccacgagca acaattggat ttcctctttg ctgctggtgc ctttggacta
     6301 gtcatcgcaa acaatgcctc catctcaggt gctgaaggtg gctgtcaagc tgaggttggt
     6361 tcggcctctg ctatgagtgc tgctgccttg actctggctg caggtggaac accttatcag
     6421 gccagtcaag ctattgcctt tgtcattaaa aatatgctag gcctcatctg tgaccctgtt
     6481 gcaggtttgg tcgaagttcc ctgtgtcaaa cgtaatgcca tgggagctag ctttgctttc
     6541 atcgcagcag acatggcctt ggcaggtatc gaatctaaaa tccctgtgga tgaagtgatc
     6601 gatgccatgt accaagtagg agcaagcatg ccaactgcct ttcgtgaaac agctgaaggt
     6661 ggactcgcta ccacccctac tggtcgtcgc ctccaaaaag aaattttcgg agaataagct
     6721 tatcaaatag gagaaaccat gatctctatc acagcgattt ttttcgattt ggatggaacc
     6781 ctcgttgata gttctatcgg gattcacaat gcctttacct atacctttaa agagctgggg
     6841 gtgcctagcc ctgatgccaa aactattcgt ggttttatgg gaccacctct cgaaagtagt
     6901 tttgcgacct gcctgtccaa agaccaaatt tctgaagccg tgcagatata tcgttcttac
     6961 tataaggcaa aaggtatcta tgaagctcaa ctctttcctc agattataga cttgcttgag
     7021 gagttatcaa gcagttatcc actctacatc accacgacaa agaatacatc tactgctcaa
     7081 gacatggcaa aaaacttgga aatccatcat ttctttgatg gtatttatgg ttctagccct
     7141 gaagcacccc ataaggcaga tgtcattcac caagccttgc agacacatca actagcacca
     7201 gaacaagcca tcatcatcgg agataccaag tttgatatgc tgggagctcg agaaacaggt
     7261 attcagaaat tggccgtcac ttggggattt ggagagcaag cagacttgct aatctatcaa
     7321 cctgattata tcgcccacaa acccttagaa gttttggcgt attttcaata gcatagactg
     7381 ggtaacaact ccatttcaga agaaaatgaa gtaatactca atgaaaatca aagagcaaac
     7441 taggaaacta gctgcgggct gctcaaaaca ctgttttaag gttgtggata gaactgacga
     7501 agtcagctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca gtaaccatat
     7561 ctacggcaag gcgacgttga cgtggtttga agagattttc gaagagtata agtctctaca
     7621 taacaaaacg cataatatca ggtgttgatg aactgcaccc caaaagttag acagaaaaaa
     7681 tctaactttt ggggtgtttt tattatgaaa ttaacttatg atgataaagt tcagatctat
     7741 gaacttagaa aacaaggata tagcttagag aagctttcaa ataaatttgg gataaacaat
     7801 tctaatatta ggtacatgat taaattgatt gatcgttacg gaatagagtt cgtcaaaaaa
     7861 gggaattcaa gcatctatgt cacgcaaggg aaacagccaa gacaacggta ggatggaatc
     7921 tttctttggc attttaaaat ccgaaatgtt ttatggctat gagaaaacat ttaaatcact
     7981 taatcaattg gaacaagcca ttatagacta tattgatgat tacaacaata agagaattaa
     8041 ggtaaagcta aaaggactta gccctgtgca atacagaact aaatccttcg gataaattaa
     8101 ttgtctaact ttttggggtc agtacatttt ttctttttta ttcaatgtgg attgtttgat
     8161 tagcaaaggc gataatagct tgcttcaact catctccact gagagtgcgg aactctccaa
     8221 tcttttgatt aatggattct aaaggcatga cattaacctt accaacgaaa atcttatcca
     8281 taacctgatt gtcaacgagt tcggttgata ccaagagctc ttcgtagagt ttttcacctg
     8341 gacggattcc aacttcaacg attggaattt cactttcagt gtggccactt agaagcacca
     8401 ttttcttggc caagtcataa atcttgactg gtttgcccat atcaaggata aagacttccc
     8461 catctttggc ataagcacca gcatggataa ccagacggct agcttctgga atggtcataa
     8521 agtaacgggt catgcggaag tctgtcaccg ttacaggccc accttcagca atctgacgtt
     8581 caaagactgg aatgacacta ccacggctac caagaacatt cccaaaacga actgcacagt
     8641 aggttgattg gctacgttgg ttaaagccag tgacaatcaa ctccgccacg cgcttggttg
     8701 ctcccataac atttggtgga ttaactgctt tatctgtcga aatcataacc atcttaggca
     8761 ctttagcttc atcaacagcc ttagcaacat tgtaagttcc acggatattg tttttgaagg
     8821 cttcttttgg attgcgctcc atcataggaa catgcttgtg ggctgccgca tgataaacaa
     8881 tagcaggttt gtactgctca aagacttgca acaagcggtc gtagtcttga atgtccgcaa
     8941 tcacaggtac ataatcaatc ccttggaact tacgaatcaa ttcatgataa acaaggtaga
     9001 ttgagttttc cccgtgaccg agcaagacaa tgcgttcagg attgaagcga ctaacttgac
     9061 gacagatttc agaaccgatt gaacctccag ctcctgtgac taagatcgtc ttacctgtca
     9121 gttctgcacc cagacgcgat tcgtcaagac ggatttcctg acgacccaaa aggtccgtaa
     9181 tatcaatttt ttggaagcca gtacctgctt ggtgaaggcc ctgaacaaca gtttcaacct
     9241 taggcatctt gtaacatttg acacccagct tattacacat ctgcaagata cgctcatatt
     9301 ctgacggatc cagcgacgga atcgcaacga tgacacgctc gatttgatgg tgtttggcta
     9361 attcaggcag attgtcataa gagcccaaaa caggaatacc accaagtttt tgaccctttt
     9421 tcttagaatc cttatccaaa ataccgacca gttctaattc actggttgga tgttggtaac
     9481 tatccataaa gagagcccca ccatcaccgg caccaatcaa gaaggtcaga cggtgttctc
     9541 catcaccact accttttttg cgtctggagt agattaactg ccaactaatc cgtggcaata
     9601 aaatcaagaa ggtactcaac aagataaaga gaatgatgaa acggatggag aagagtggca
     9661 agaaggcata acagatacta tatgacaaga cactgctagc agtcacacca aaaaagattt
     9721 tcatgaaatc cgtaatcttg ctgtaacgac taatactcgc gttcaagccc caaaatgcaa
     9781 tcatcaattg ataaaacaag aaggccaaac tcgtatagat aatgtagtca acaggtgctg
     9841 gattaatcag cccataaaat aaaatataag atacaatgat ggaaaccacc atactgaaaa
     9901 tatcaaatat tccccagaaa acctgctttt gttgtttatt taaaatttcc accagatcaa
     9961 tcacataatc tgttagtttt ttattcatag aaatctactc ctccttaaaa gagtttcact
    10021 atattgttat tatagcatat tttgatttat ttggcttatt ttatccaaat aaattattgt
    10081 tcccttgtac tccttcttcc atttaaatcc tctaattaaa cctacaatcg tcccaaagcc
    10141 ataagcaaag tgaatggaaa ataaaagaaa gggcatcaca attagaaatc catttttatg
    10201 ttttaataaa gtcagcaaag tgagtagtga caaaagtaga aaataggcac ctaatagtaa
    10261 agttatgaat acgaatgtga tcggtaacaa tgctagacta aacacaagac tcaaaacaaa
    10321 taaacaagga acatagtgaa ataatgataa acacttaaac tgaacatgac ttgtcaagcc
    10381 aatccacaaa ccatttaaat acttttgatg cagcattttc ttgaatgttg gtcgaatata
    10441 ctgataagat agaatacttg ggctatagcg gattttataa ccatgttctc gaattctata
    10501 atgaatatca ttatcttcag ttcggccaag ttgctcattt actaaaccaa ccttctggaa
    10561 aacctctcgt ttatacatcc catgaaaaat agaagaaaca tatctatcct cggaactatt
    10621 tcgataattg gcaatgctac tgccaaacat attttcctca acaagatgca aggtctctgc
    10681 ccattttcct tttccttcga caatcgtcgg tctaggcccc ccacagacaa attcaccttg
    10741 ttgaataata gccacattgt tcattacaaa actctcagta acttttgaat gagcatcaat
    10801 ttttaaaata aggtccccta cagaatgttt aactcccagg ttaaaaccac tagcttgatt
    10861 tttcttagga ttgttataca atctaattga gttaaactct gtatcttcct ttataaattg
    10921 ctgaatgata gctgtggtcc catctgtgga catagcattt ataaatagaa tttcaatatt
    10981 ctctttagga taggtttgat tttttaagtc ttcaattaga ccaggcagat atttttcttc
    11041 attgtatgca ctgattacaa tggatacgag aagactttca acattttgag tcactactac
    11101 tctcctgaat ttttccttcc accattctat cataattttc aagactttcc catttttatc
    11161 ttgaaagcca gaaaccttac ttgacattat agtgaaaaag ccttaaaata agctgttatt
    11221 aaaatcagct agaagaggta ttatatgaaa aagcaatcac tcttttttgt tccaggtatt
    11281 atcctgattg gtgtttcctt gcgaactcct tttactgttt tacccattat tttgggaaat
    11341 atttcgcaag gtctggaggt agaagttagt tcgcttggtg tcttgaccag cctgcctctc
    11401 cttatgttta ccctcttttc accattttct acccaactgg ctcagaaaat cggcttggag
    11461 catctcttca cctacagcct cttcttcttg accatcggct cacttattcg actaatcaat
    11521 ctgcccctgc tctatctagg aaccttgatg gttggggcaa gtgtcgcagt catcaatgtc
    11581 atgcttccta gtcttatcca agccaatcaa ccaaagaaaa ttggttttct gaccacctta
    11641 tatgtaacgt ctatggggat tgcaacggct ctggcttcct atctagctgt gcccattaca
    11701 caatccagtt cttggaaagg acttatcctc ctcctcacat tactctgtct agcaactttt
    11761 ttggtctggc tcccaaatca ccgctataat catagactag ctccacaaac caaacaaaaa
    11821 agtcaaataa aggtcatgcg taataaacag gtttgggcaa ttattatctt ttcaggtttt
    11881 caatccttga tcttttacac cgtcatgacc tggttaccta ccatgtctat ccatgcaggt
    11941 ctatccagtc acgaagctgg cttgctgact tctatcttat ctctgattag cattcctttt
    12001 tcaatgacca tcccaagcct gacaaccagt ttatctactc gcaaccgtca gctcatgctc
    12061 actctggttt cactagctgg tgtggtcggc atttccatgc tctttttccc aatcaataat
    12121 ttcatttact ggcttgccat ccatctcctc atcggaaccg caaccagcgc cctcttccct
    12181 tatctcatgg tcaacttttc actcaagaca agcgcccctg aaaagacagc ccaattgtcc
    12241 ggcctatctc aaacaggagg ctatatccta gcagcctttg ggccaaccct ctttggttac
    12301 agttttgacc tattccactc ttgggtacca gctgtagctg ccctcttgct catcgatatc
    12361 ctgatgactg tagccctctt tacagtggac agagcggata agatccttta aacttctagt
    12421 tttagctaga agttttttat atataaaaat tttacacatt tctcttgaca gggctttctt
    12481 ttagatgtac aatgtatgtg tagaaaaatt atatataaaa atcttacaca ttagaaaagg
    12541 aggtttccca tgtactttcc aacatcctct gccttgattg aatttctcat cttggctgta
    12601 ctggagcagg gtgattctta tggttatgag attagccaaa ccattaagct gatcgctaat
    12661 atcaaagaat ccacactcta tcccattctc aaaaaattgg aaggcaatag ctttctgaca
    12721 acctattcta gagagttcca aggtcgcatg cgcaaatact actccttgac aaacggtggt
    12781 atagagcagc tcttgaccct aaaagatgaa tggacactct atacagacac catcaatggc
    12841 atcatagaag ggagtatccg ccatgacaag aactgaatac ctgactcagc tagaactcta
    12901 tctcaagaaa ctacctgaag ctgaccgtat cgaagccatg gactatttca gagagctctt
    12961 tgacgatgct ggagtcgaag gagaagaaga actcatcgct agtttgggaa ctcccaaaga
    13021 agtggcccac gaagttctat ccaatcttct cgataaaaaa atcaatgaag cacccgctca
    13081 aaaaaataac cgacaaattt tacatatcgc cttgttagcc ctccttgcag cacctatcgg
    13141 cattcctctg ggaatcgcca tcctcgtgac cctgttcgca atccttgtag ccgctttgac
    13201 tgtcattctg gctttctttg cagtttccat actgggtatc atcggcggat tcctattttt
    13261 agttgaaagt ttcactgtcc tcgcccaagc caaatcagcc tttatcttga tttttggttc
    13321 tggtttactg gctatcggtg cttcttcgct agttttacta ggcatttcct atgtagctcg
    13381 cttcttcggt ctactcattg ttcgcctggt acaatttgtt cttaaaaaaa gaaagagagg
    13441 taaccagcat gcgtaaatgg acaaaaggat ttctcatctt tggtgtggtg actaccgtta
    13501 tcggctttat cctgcttttt gtaggtatcc aatctgacgg gattaagagc ctactttcca
    13561 tgtccaaaga acctgtctat gatagccgta cggaaaagct aacctttggc aaggaagtcg
    13621 aaaacctaga aattactctc caccaacacg cgctcaccat cacagactct ttcgatgatc
    13681 aaatccacat ttcttaccat ccatctcttt ctgctcacca tgatcttatc accaatcaga
    13741 acgatagaac tctgagtctc actgataaga aactgtctga aactccgttt ctctcttctg
    13801 gaattggtgg gattcttcat atcgcaagta gctactctag tcgttttgaa gaagttattc
    13861 tccagctacc aaaagggaga actctaaaag ggatcaacat ctcagccaat cgcggacaaa
    13921 ccaccatcat aaatgctagc cttgaaaatg cgaccctcaa tacaaacagc tatatcctcc
    13981 gaattgaagg aagtcgtatc aaaaacagta aactcacaac acccaatatc gttaatatct
    14041 ttgatacagt tcttacagat agtcagctag agtcaacaga gaatcacttc cacgctgaaa
    14101 atatccaagt ccatggtaag gttgaactga ctgccaaaga ttatctcaga atcatcctag
    14161 accagaaaga aagccaacga attaactggg acatctcaag caactatggt tctatcttcc
    14221 aattcacaag agaaaagcct gaatcaagag gtacggaatt aagcaaccct tacaaaactg
    14281 aaaaaaccga tgtcaaggat caactcattg cgagatctga tgataatatt gatctaatat
    14341 ccacaccaag cagacgttga caaaaacgct tacatctgct actatggaag catatttatc
    14401 taactaaaaa ggaggttcta ccatgaaaca agaatggttt gaaagtaatg attttgtaaa
    14461 aacaacaagc aagaacaagc ctgaagagca agctcaagag gttgcagaca aggctgaaga
    14521 aacgatagcc gatctcgata caccaattgg aaaaaatact caagtagagg aggaagtctc
    14581 tcaagctgaa gtcgaactgg aaagccagca agaagagaaa attgaaactc ctgaagacag
    14641 tgaagcgaga acagaaatag aagaaaagaa ggcatctaat tctactgaag aagagccaga
    14701 cctttctaaa gaaacagaaa aagtcactat agctgaagag agccaagaag ctcttcctca
    14761 gcaaaaagca accacgaaag agccacttct tatcagtaaa tctttagaaa gtccttatat
    14821 ccccgaccaa gctccaaaat ctagggataa atggaaagag caagtgcttg atttttggtc
    14881 ttggctagtg gaagcgatca aatctcctac aagtaagttg gaaacaagta tcacacacag
    14941 ttacacagcc tttctcttgc tcattctgtt ttctgcatct tcctttttct ttagtatcta
    15001 tcacatcaaa catgcttact atggacatat agcaagcatt aacagtcgct tccctgagca
    15061 gctagctcct ttaactcttt tttctatcat ctctatccta gtagcgacaa cactcttctt
    15121 cttttcattc ctcttgggta gtttcgttgt gagacgattt atccaccagg aaaaggactg
    15181 gacgctagac aaggttctcc aacaatatag tcaactcttg gcaattccaa tcttcctcac
    15241 tgctattgct agtttctttg ccttctttga tagcctacga tttacagctc tcttgtgtgt
    15301 gattagcatt ggaatcattc tgcttgccag tctccatatc attacaagac caagtcaagc
    15361 aagtgaaacc gactccttct atcaattatt cttgtctgtc cttgtgaacg gagttattat
    15421 cctcctcttc tttgtagctg aagtggcact gattggagat tatcttcgta tcttggcctt
    15481 tctttaaact tcatactctt cgaaaatctc ttcaaaccac gtcagcttcg ccttaccgta
    15541 ctcaagtaca gcctgcggct agcttcctag tttgctcttt gattttcatt gagtagcaat
    15601 cctgtcttcc atggcaggat tttttctatg tcaaaaaagc aagtcgattg acctgcttct
    15661 gctttacttt tcttgtgcta atgttttaaa atctttgtcc taggatgggt tgtatttcta
    15721 tttgattggc gtctagttgg tggtaaaaag atgggggtaa tacctctaag aattttgcat
    15781 agtccaagcg ggctatggct tcatagtctt ctggtttaga gccgtctcct gtgatttgaa
    15841 ccaagtcaat ctcccactgc acttccttat ccaccaattg ctcaatatag gctgcaggaa
    15901 caaacggttc tctcggtaaa actgtcttga ctccttgagc tagatggtaa acgccatgca
    15961 cttttccttc tccatcctga tagaaggaaa ctctcgcaaa gtaggcatct gtctcttgaa
    16021 ccgcacacgc gcttcaaact gagccaagcc atctgcctct aaaaaacttt tcaagttctc
    16081 acgactaaag aaaataggat taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc
    16141 tgctagatag gcttgaatac ttgcttggaa ataagcttca aaatcaaaac catctagccc
    16201 ttcaatatca gtccctgtat aagcaagcaa agcatctaaa aatgacttga taatctgcca
    16261 gtctgtcttt gttagtaggt caggaagatc gacacggtaa gccttttgac catcagcata
    16321 actgacctta aagagaaatt gtgattgccc cactatcgca cactcgatat attcgagacg
    16381 attaagaggc tgacggagat agactacatc atagctatgt gactccaaac cgtctagcaa
    16441 ggccaagatc gacttggcat tcaaaatctc ttgctctcct aaaatgctct gtttatttgg
    16501 aataaaaaat gttttcgcca taattggacc cctttaaaat cgtttacata cagtatacct
    16561 tatttttatg aaagatacaa aaacaaactt tatactcttc gaaaatctct tcaaaccgcg
    16621 tcagcttcgc cttgccgtag atatatgttc ctgacttcgt cagtttcatc tacaacctca
    16681 aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gctctttgat tttcattgag
    16741 tattagattt ttgagtacaa agcatagaaa aacagcccct gaggactgtt tgatcttata
    16801 cagtagctgc ttgatccaag ctttcaccga tagcggctag gcgctcgatc acttcagctt
    16861 gtgtcaattc attttttgaa acatagcggt tacgtgggtg aacacggcac tcgtgtgagc
    16921 atccacgaag gtacttgtct tcattttctt ctgatgtcaa gatacgacgg ttacagaagg
    16981 gatttccaca gttgacataa cgttcacatg gtgttccatc aaaccagtct ttccctacga
    17041 tggttgggtt gacatggttg acatcaacgg cgatacgctc gtcaaagacg tacattttcc
    17101 catcccaaag ctcaccttga acttctgggt ctttaccgta agttgcaatt cctccgtgca
    17161 attggccaac atctttgtaa ccttcacgaa ccatccagcc tgagaatttc tcacagcgaa
    17221 caccacctgt acagtaaacc acgacacgct tgtccatgaa tttttctttg ttgtcacgaa
    17281 cccattgtgg caactcacgg aagttgcgaa tatctgggcg aatagcccca cggaaatgtc
    17341 ctaggtcgta ctcataatcg ttacgtgtgt caaggacaac ggtatcttta tcaagaagcg
    17401 cttctttgaa ctcttttgga gacaagtaag cacctgttgt ttcaagtggg ttgatgtcat
    17461 tgtcaaagtc gttgtcttcc aaaccaaggt ggacaatttc tttcttgtag cgaacaaaca
    17521 tcttcttgaa ggcttgttca ttttcttcgt caatcttgaa ccagagttct tccattcctg
    17581 gaaggctgtg aacgtagtcc atgtattttt gagttgtttc atagtcacct gaaactgttc
    17641 cgttaattcc ctcgtcagcg actaggatac ggcctttaag accgattgat ttacagaaag
    17701 ccaagtggtc tgcagcaaat tgctctgcat tttcaattgg agtataaagg tagtaaagta
    17761 agacacgaat atcttttgcc ataagatttg ttctcttttc tattcttaaa ttttctaaat
    17821 tttttattta tctacactag tatacctgct tgagaaaacg aatgcaattt atttgactgg
    17881 aaattgtaga gggttctcaa aatttcctga atggttaaaa taaggacaag agaaaacatg
    17941 gatatctata tccttgtgcc aaaaaaacca ctgccctccc cagaccaacc tgaggaaagc
    18001 agtgattctt attttaggag ttaggaatga atacacgaaa tcaatttagc tgattatttt
    18061 ttgtttttca agaattcatc gtattgtttt tgcatttcat tcaatacttt ttcgtaggca
    18121 ccttcagatt tcaacttttc catcaattct ggaatcgctt tatctgggtc tacagtacca
    18181 gtgttgatag ctgtatcaaa ttgttgcatt gtgttagcaa tagctgagat ttcagatttc
    18241 acattgtcag tattgaagat aaatccaagc gctggagatt ctttagcttc tgccaattct
    18301 ttcttagaat tttcgatttg ttggtctgta acgttttcgt tgatgtaaag gatccagttg
    18361 ttaccagtgt tccatccacc catgtgagtg tttcctttgt agccatcaag aacgcgaaca
    18421 cggttttctt taccttcaat tttttcccag ttcttgcctt ctggaccgta aacaagaccg
    18481 ttcaagagtt ctggattcgt attcaagagg ttcaagattt ccattgattt ttctttgttc
    18541 ttagagttgt ttgagatgac aaagttagca acttgtgttg tttggttttt cttgatgaag
    18601 ttagtaattg gtttgatttg gatatctttg ttggcaacac gtgaaagcaa gctgttaccg
    18661 tagtcagctg gtcctactgt ttcttcacga acgaaccaag tatcttgttg aaggtcaaag
    18721 gaagtatcgc ttgttgcgac atcttttgga atgtagccag cttcatagaa tttgtgaaga
    18781 gtcttcaagt gttctttgaa acgaggcact tcgtaacggt ttacaacttt agtagtatcg
    18841 ccttcaagat caataacgaa tggaagcccg tttgctactg ggtagtcaaa gttatcagat
    18901 gggatgaaaa ctttaccaat agcaaatggt actacgtctg gagctttttc tttaatttgt
    18961 ttcaagactg gctcaagagt ttcgtaagaa gtaacacctg aaatatcgat accatatttg
    19021 gcaaggagag ttccgttgaa ggcaaagttt tgagatgatg caacgttggc tgcaactgga
    19081 acagcgtaaa ttttaccgtt tacagtatta cccttgatgt aagctgggtc aagtgccttg
    19141 taaaggtctt taccttcttt tttgtacaat tctgtcaagt cagcataagc acctttttga
    19201 gcatttacaa tatagttatc tgcaaaggcg atatcatagt tttcaccaga tgatgtgata
    19261 actgacattt tcttaccata gtcaccccag ccaaggtatt ggatatccaa tttagcacca
    19321 actttttctt cgatgatttt gttggcattt gctaacaatt catccaagtt atctggtttg
    19381 tcaccgattt ggtacatttt gataacaggt ttgtcacctg aatcagcagc ttttttgctg
    19441 ttacctgtca agttgccaca agcagcaaga cctgcagcca gagcgactac actagcagat
    19501 gcaaaagcat attttttcca gtttttcatg ataaaaactc ctttttttat ttttaaactt
    19561 ataaacaatg taatgatctt atactcaatg aaaatcaaag agcaaactag aaaactagcc
    19621 gcaggctgct caaagcactg ctttgaggtt gtagataaga ctgacgaagt cagttacata
    19681 tatctacggc aaggcgacgt tgacgcggtt tgaatttgat tttcgaagag tattaacttc
    19741 acacaaggga agttgggaac tgagaaatgt tatttctcaa taagcactat tctttcacac
    19801 caccgatagt caaacctttt acaaagtagc gttggaagaa tggatacaaa atcgcgattg
    19861 gaagggttgc taccacaacc atggccatac gacctgtttc tttcggtaga gcaactccca
    19921 gttgaccagt caagccgacc gctttggcaa tgtagtccat attttgttgg atttgcatga
    19981 gcaaatattg caatggatac aagttgtcac tcttgatgta aagaagggcg ttgaaccagt
    20041 cattccagaa accaagagct gtcaaaagcg tgatggttgc gatacctggt agtgacaatg
    20101 gcaaacagat ttggaagaaa atccgggcct cactggcacc atcgatacga gccgattcga
    20161 gaatggcttc tggaatggtc ttcttgaaga aggaacgcat caagatgata ttgaatggtg
    20221 agagaagcat tggaacaatc aaggcccaaa cagtgtcacc aagctgaagt acacgggtca
    20281 ccatgatata acctggtacc aaaccagcgt tgaacaacat actgagaagg acgaagatgg
    20341 taaaaaatct gcgatactta aaggttgtcc gtgaaatagc gtaggcatag gttgttgtga
    20401 taaagacatt tgtcaatgtc ccaactacgg ttacaaagac agagatgaag agggcttgta
    20461 ggattttatc cttaaactgt gccaaaaact caaaaccgtc taagccaaat tgggatggga
    20521 agaagctata gccgtattgg aggaggcttt tctcgtctgt cactgaaata atgataacga
    20581 atacaaaagg taggatacaa gagagggcaa tcaaacccga aatgatactg aagaagatat
    20641 ctgctttctt actgaaggag tgaatgccga cattatcaat tttttctttt ttaattttct
    20701 tttttgccat attctcctcc tttctagaac aaagctgagt ttggatcgac tcgtcttgca
    20761 agcaagtttg ataggataac cagaatcaaa ccaacaacgg attggtaaag accggctgct
    20821 gcagccatac cgatatctgc tgtctgagtc aaaccattaa agacatatac gtccaaaacg
    20881 ttggttacat tgtaaagctg accagcattg tgtgggattt gatagaagag accgaagtct
    20941 gcgcggaaga tatttccgac tgcaaggatg gtcaatacag ttacaagcgg agtcaactga
    21001 ggaatggtta cgttgcgaat acgttgccac ttgctagctc cgtccactgt cgctgcttcg
    21061 tagtaggttg gatcaattcc catgatcgtc gcatagtaca tgacactgct atatccaaag
    21121 cctttccaaa tacctaggaa aagtaggaga tagggccaga tgcccaggtc agcgtaaaaa
    21181 ttgacttctt tgagaccaag actttccaat agatgattga acaccccttt atcaatattt
    21241 aggaaggcat ctgtaaagaa actgatgata acccaagaca agaagtaagg gaacaacata
    21301 gaagtttgga aaatcttcac cattctctta gaacggagct cgctgaggat aatggcaatc
    21361 cctacagata caactaaacc tagaaagata aagccaagat tgtagaggac agtatttcgt
    21421 gtgataataa aggcgtctct tgaactaaat aagaatctga aattatcgag tccgacccat
    21481 ttactattta tgatactatc tatgaaacca ttactggtca tgtggtagtc tttgaaggca
    21541 accacgttcc caaatactgg aatgtaaaag aatagaatca accagagtgc ccctggcaaa
    21601 accatcaaga gaaagatcca gttgtctctc aatgtttttg aaaacttttt cataatttcc
    21661 tcccttttta ttttgatatc catctaaaaa ttctttttta gacttttgat aacgattaca
    21721 ttattagtat actcctattt gcaggttagg ttaaactcct aattatagaa aaaactccac
    21781 aaattatgta gcagatttaa aactttatca ccactatcaa acaaatgtcc taaatcaatt
    21841 gtttatttta tctctattag cccagtgatg gcgtcactct gttataagca tccaacaacg
    21901 gggtatactg aaaaatctcc agactaggga actcagcgat agttcctaat ctggagattt
    21961 ttaatatgtt attaggcgtt tgctttcaac ttagcaataa cctctttaag attatcaatc
    22021 aactctgctt cagtatgctc agagcctttt tcatctgcca agaacaaaac tgctttttga
    22081 agttcttctt gagagttttc aaggacatcc ttatctactg tttcaaggtt tgagtctgct
    22141 tactaatact agactaaaat caaaaagcat tatataatag taatatgaaa tcaactaaag
    22201 aagaaatcca aaccatcaaa acacttttaa aagactctcg tacagctaaa tatcataaac
    22261 gccttcaaat cgttctatag taaaatgaaa caagaacaag acaaatcgat ttctaacaat
    22321 gttttagaag tagaggtgta ttattctagt ttcaatccat tatatttcgt ctgatgggca
    22381 aatcttataa agagattata gaacttttat agtagtttga aataagatgt gaacaactct
    22441 atcaggaaag tcaaattaat ttatagaaat attttagcag ccaaggtgta ctgttataga
    22501 ttcaatacac tatacttggt ggtttagctc tcctgttttc tcttttggct ttaaccagcc
    22561 ataaatggta ttacgtgaga tttggaaaac gtgtgatgct tctgttatac tacctgttcg
    22621 ctcacaataa gagagaactt ttttacgaaa atctattgaa tatgccataa aaagattata
    22681 ccacattgtg tactattttt ggttcatttt actatatcac tttggactat atcggtctag
    22741 ttatgtctaa acgattatag ctggatacta agagaaatca aaaaaagcac tctaggatag
    22801 aggcctaaag tgcttagttt caaggcttta cagcctatca tatttaataa aatattacaa
    22861 cattttgttg tagaattcaa cgacaagtgc ttcgttgatt tctgggttga tttcgtcgcg
    22921 ttctggcaag cgagtcaatg aaccttccaa tttttcagcg tcgaatgata cgaatgctgg
    22981 acgtccaaga gtagcttcta ctgcttcaag gattgctgga actttcaatg atttttcacg
    23041 aactgagatc acttgacctg gagttacgcg gtatgatggg atatcaacgc gtttcccgtc
    23101 aacaaggatg tgaccgtggt ttacgaattg acgagcttga cgacgagtag tcgcgagacc
    23161 aagacggtaa acaacgttat ccaaacgacg ttccaaaaga agcataaagt tgaaacctag
    23221 gattccgcct ttgatttttg tagcttgtac gaacaagtta cggaattgtt tttcacctac
    23281 accgtaagtg aaacgaagtt tttgtttttc agccaattgc aaaccgtatt ctgacaattt
    23341 agaacggttg tttggtccgt gttgtcctgg tacgtagtta cgacgtgcca attctttacc
    23401 tgtacctgta agtgaaaggc caaggcgacg agcttgtttc caagatggtc ctgtataacg
    23461 tgacatatga atgtcctcct gatataaata atatttcggt ggaaatagtc acttagaaag
    23521 ccctgattcg tgcagatgcc cttcgcctaa acagccaagg ttacttgtca taagacacct
    23581 gttgacgagc ttcatgcttt cctgctgata tttcacacaa aatctattct accatgaata
    23641 gctggatttg taaaggggtt ttaggcttta ttttcactac cagagaggtt gagaacgagg
    23701 gtaaaggtac ttcctagacc gtactggctg ctgactgtga tttccccacc caattgatgg
    23761 gccaattcac gcgcaatcgc aagtcctaat ccatgaccac ctgtcttcat gttacgcgaa
    23821 gtttcgacac gataaaggcg tttgaaaata ttttccaaat cctctggggc aataccctgc
    23881 ccttcatcgg tcacactgat tgaaagctgg tccttctcca gcttagccac cacttccagc
    23941 ttggttcctg gagcagaata tttaaaagcg ttatcgacca gattcaccaa gatacgagaa
    24001 agcttagcat aatctccctc aatccgggca gactctggga ttacctgcaa gtggacatct
    24061 cttctctcct gctcaatcaa aaactgaaat tcactcatgc actcaattaa gagcttgtcc
    24121 agaaaaatac tgtctttact ggtagtttcc acctgatttc tagctgtgtt tagggtcaaa
    24181 aaattcaact cctcaaccag tttattgagc ctctccgtct ggcgtccaat ggttgctaga
    24241 taatgagctt gctccgactc cttgataatc ccatccaaaa tcccttctac cgtcgcttgg
    24301 atcgaagtga taggagtctt aatatcatgc gacaactgag caatcatcaa gcccttttct
    24361 cgttcgcttt cttccaagga atcaaagctt acctgcaaat catgggacat ctcattaaaa
    24421 gtttgcccta attgctgaaa ttctacagga ccttgaacct ccaaatttga aggaaaatcc
    24481 ttggccgcta cccgcttggc atgctccttg agtttgccca acgacgtaaa gactggcaat
    24541 aggagaaaga gactaatccc agcaccgaca aggctggcaa cgatggtcat cccaagcaaa
    24601 aagtaaatct cgcctttcgc aatcagcatt ttttgaacag cccaaaaaac aaccaaaatg
    24661 gttaagaggg ttgaaataat atatccaacc aaaatataac tttttagttt catgtttgtc
    24721 ctctcggttt ctctatctta tatcccaacc cccaaactgt cttaatagtg ggcgtttggt
    24781 cactactata ttttgccagt tcctgtcgaa gagcatggat atgcacattc aaggtattgg
    24841 tgtcatccac gtagtcttct ttccagatct tttcatagag gtctgtcttg gagaaaactc
    24901 gctctggatt gctagctaaa atccacagca attcaaatga tttaacagtt aaatccagca
    24961 tttcttctcc tatttgaact tcatgactac tatgattcat ttttagattg ccaagggaaa
    25021 tcagctctgt ttcgccccca cgatgaaggc ggcgcaaaat attgtggaca cgcaaaacca
    25081 gctcacgtgg gctaaaaggc ttagcaataa aatcatctgc tcccaagctc aggccgtaaa
    25141 tcttgtcctg ttcactggtc ttagcagtaa taaataggaa aggctgctct ggtgataagt
    25201 attgaacctc actgattaaa tcataaccat ccatccgagg catcatgaca tctgtgataa
    25261 tcaaatcaat cggttttttc ttgaacagct ctagcgcttc cagtccatca tgggctacca
    25321 agacctgata acctgcctga attaagtatc tctgatgaat atctgtgatt tctacctcgt
    25381 catcaacgag taaaattgtc tttcccatct gtctctcctt tgataaaaac agtgctatac
    25441 tgctttaagt ataacactat ttttattgtt ttacgatgat tttaatctgc tattgaaaga
    25501 aagtcctgat tgctgattga gttggtaaac tagccttagt cagcccacta tccatcattt
    25561 atttccttag ctgattagtt ttcttctttt ttgtttttca aacctagacc accgagtaaa
    25621 cctgcaagcg caagcccaag gaaaccaata cttgccattg atgtttgagt ttcaccagta
    25681 tttggtagca tagctttatc atctgacatc atcgtatcag acatcttgtt agcagaagca
    25741 gccatgtttt cacctgccat cgtgttggta gaacttgcca tggtatcagc aggcatgcta
    25801 tttgtagtac ctggagctgg agtttcaggc ttcatacctg attttttcat ctgatcattt
    25861 gctgtgtctg atgtttcttt aacatttat
//
LOCUS       DAVDHZ010000029        25872 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000029 DAVDHZ010000000
VERSION     DAVDHZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25872
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.030"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(431..886)
                     /locus_tag="VUR46_001464"
     CDS             complement(431..886)
                     /locus_tag="VUR46_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456868.1"
                     /translation="MGAARDFLELINYKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(1212..2900)
                     /locus_tag="VUR46_001465"
     CDS             complement(1212..2900)
                     /locus_tag="VUR46_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HET5456869.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQLFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DHHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNC"
     gene            complement(3063..3896)
                     /locus_tag="VUR46_001466"
     CDS             complement(3063..3896)
                     /locus_tag="VUR46_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET5456870.1"
                     /translation="MDYKEKLENKAKEYFEYVETKITEKALDATHFAEEASREQYDAV
                     VVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLEINQDIDGAIDELDFDLT
                     NKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILTYAVNTMKSVMTDQVFNI
                     KVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANILILKDASIFSKLSVIPDL
                     LKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPVEIKVLAQRVEVFSKPKE
                     D"
     gene            complement(4058..4912)
                     /locus_tag="VUR46_001467"
     CDS             complement(4058..4912)
                     /locus_tag="VUR46_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET5456871.1"
                     /translation="MLGAITGDIVVSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(4970..5728)
                     /locus_tag="VUR46_001468"
     CDS             complement(4970..5728)
                     /locus_tag="VUR46_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET5456872.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMEIRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYELDIGVTRDGRTLVVEVNDGYALGNCGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(6029..6595)
                     /locus_tag="VUR46_001469"
     CDS             complement(6029..6595)
                     /locus_tag="VUR46_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456873.1"
                     /translation="MVILELYQNDYSKDLVAFNSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESCGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(6863..8221)
                     /gene="rlmD"
                     /locus_tag="VUR46_001470"
     CDS             complement(6863..8221)
                     /gene="rlmD"
                     /locus_tag="VUR46_001470"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET5456874.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTDSFI
                     KASAQTGVDRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVECVSLLEK
                     RN"
     gene            complement(8295..9269)
                     /locus_tag="VUR46_001471"
     CDS             complement(8295..9269)
                     /locus_tag="VUR46_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET5456875.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVTFFKSFGS"
     gene            complement(9343..9957)
                     /gene="pmp23"
                     /locus_tag="VUR46_001472"
     CDS             complement(9343..9957)
                     /gene="pmp23"
                     /locus_tag="VUR46_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET5456876.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSISG"
     gene            complement(9957..10931)
                     /locus_tag="VUR46_001473"
     CDS             complement(9957..10931)
                     /locus_tag="VUR46_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET5456877.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSENLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(10939..12195)
                     /locus_tag="VUR46_001474"
     CDS             complement(10939..12195)
                     /locus_tag="VUR46_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET5456878.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVESLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMALIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFRETADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHIVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQAPDFRIISGGTENHLFLVDVTKIVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     AENEAVLEEVRSAVKELTDSFPLYED"
     gene            complement(12256..12687)
                     /locus_tag="VUR46_001475"
     CDS             complement(12256..12687)
                     /locus_tag="VUR46_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456879.1"
                     /translation="MLRDLRETDVKAICEINQEALGYSFSPEDTASQLAKLSQDSHHF
                     LLGYEDAASHVLLGYVHAEVYESLYSKAGFNILALAISPQAQGQGIGKSLLQGLEQEA
                     KRRGYGFICLNSADHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            complement(12689..13291)
                     /locus_tag="VUR46_001476"
     CDS             complement(12689..13291)
                     /locus_tag="VUR46_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET5456880.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDCVYQLKRR
                     PRDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TVGFRMPSHPITLDLIRETGPLIGPSANISGQTSGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTILDLSGDKVKILRQGAIKREDILAQLPEISFEEE"
     gene            complement(13275..14114)
                     /gene="prmC"
                     /locus_tag="VUR46_001477"
     CDS             complement(13275..14114)
                     /gene="prmC"
                     /locus_tag="VUR46_001477"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET5456881.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLATHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLEENLQVLDIGTGSGAIALALAKNRPAWSVTAADISQDALELASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREGESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPALFKKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(14114..15193)
                     /gene="prfA"
                     /locus_tag="VUR46_001478"
     CDS             complement(14114..15193)
                     /gene="prfA"
                     /locus_tag="VUR46_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET5456882.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(15190..15780)
                     /locus_tag="VUR46_001479"
     CDS             complement(15190..15780)
                     /locus_tag="VUR46_001479"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET5456883.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            15903..16085
                     /locus_tag="VUR46_001480"
     CDS             15903..16085
                     /locus_tag="VUR46_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET5456884.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            16222..17595
                     /gene="mnmE"
                     /locus_tag="VUR46_001481"
     CDS             16222..17595
                     /gene="mnmE"
                     /locus_tag="VUR46_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET5456885.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(17642..18577)
                     /gene="dapA"
                     /locus_tag="VUR46_001482"
     CDS             complement(17642..18577)
                     /gene="dapA"
                     /locus_tag="VUR46_001482"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET5456886.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(18633..19709)
                     /locus_tag="VUR46_001483"
     CDS             complement(18633..19709)
                     /locus_tag="VUR46_001483"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET5456887.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(20294..20366)
                     /locus_tag="VUR46_001484"
     tRNA            complement(20294..20366)
                     /locus_tag="VUR46_001484"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20331..20333),aa:Thr,seq:ggt)
     gene            complement(20466..20975)
                     /locus_tag="VUR46_001485"
     CDS             complement(20466..20975)
                     /locus_tag="VUR46_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET5456888.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(20973..21069)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            21098..21529
                     /locus_tag="VUR46_001486"
     CDS             21098..21529
                     /locus_tag="VUR46_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET5456889.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQILIIIINYILSKIYIFRK"
     gene            21611..21988
                     /gene="mscL"
                     /locus_tag="VUR46_001487"
     CDS             21611..21988
                     /gene="mscL"
                     /locus_tag="VUR46_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET5456890.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(22030..23124)
                     /gene="hemH"
                     /locus_tag="VUR46_001488"
     CDS             complement(22030..23124)
                     /gene="hemH"
                     /locus_tag="VUR46_001488"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET5456891.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEDRLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILEEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            23279..24502
                     /gene="pepT"
                     /locus_tag="VUR46_001489"
     CDS             23279..24502
                     /gene="pepT"
                     /locus_tag="VUR46_001489"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET5456892.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNLLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(24538..25167)
                     /locus_tag="VUR46_001490"
     CDS             complement(24538..25167)
                     /locus_tag="VUR46_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456893.1"
                     /translation="MSKANQLLEQIHEEGIRKSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETGSDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            25132..25353
                     /locus_tag="VUR46_001491"
     CDS             25132..25353
                     /locus_tag="VUR46_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456894.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(25415..>25872)
                     /locus_tag="VUR46_001492"
     CDS             complement(25415..>25872)
                     /locus_tag="VUR46_001492"
                     /inference="COORDINATES: protein motif:HMM:NF016182.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET5456895.1"
                     /translation="IVRHGDHYHYIPKSSLNNPPSHSNTEEVGSSSSSVLSNPSLHVH
                     HEEEDGHGFDANRIISEDSEGFVIPHGDHNHYIKVQTKGYEAALKNKIPSLQSNYQPG
                     TFDEKAVLAKVDQLLADSRSIYKDKPIEQRQIELALGQFTESLKKIKVS"
BASE COUNT         7546 a         5493 c         4662 g         8171 t
ORIGIN      
        1 tttttataaa tccattatag cataaaaaag cataacgcac caaaaatggt gcgttatttc
       61 ttgtttgtct atcctaaact ttacttctat aaaagtcacc taaagagcca taaatattta
      121 ttcttgtatt aattttttcg atgcgcaaac gatatctaca aatacatcta taacgattca
      181 ccttttagga tttttattgt caaaattgtc tttatctaca aagacaaaat gcttataaaa
      241 tagcttgaaa tcaaggatta tcaccttttt cgttgtagca acactccaca tgtgattatt
      301 aggctattag caaagcgtat ccaatacctc aataaagtgt tgtttttact gatattttaa
      361 ctatattgta tagtctacta tttaaatctc aattaggata ttttatagaa tacccaaaat
      421 tcaacaataa ctaaaagtaa gattccattg tatttccttg ttggtctttc atatcacgaa
      481 ttttattttt cagaatatta aagttacaaa tttcatctct aatatcgtta tccgctctgt
      541 agccattaat catctcagtc agagttttcc ctttactacc attctttata gtagtattta
      601 ctctttttat actgctttca aaaggctcat atgttttata cttaattact tcgtctttaa
      661 aattaaataa aggtgtatcc ggcttagcat tccataaaat aatcaaccac attatagcat
      721 tataaagctg ctttgcagtt tcattccact tttcaggttg taaatttcca ctccctgtat
      781 tgtcatattc ttgtctatta tttacatgag aatcacctac aagcggatta aaaagaggta
      841 gccctttgta attaattagt tctaaaaaat cccttgccgc acccatgcaa cactgaataa
      901 cttccttctt gccatcaatt ttactctcag cgataaatac ataatattca tcttcaatag
      961 ttgctcctgc atcactatgt ttttgttgat ttgctaacag cttaatatgt gctttaggct
     1021 aaacttcaaa atctctaaca attctttgtc ttgtttcatg tcctctacaa ttcatttaag
     1081 ttctccttta caagtttagt aactagcctt attatactat ataagatatg aaatgtacca
     1141 taatcttcat caactagttt ttagaaaatc acaaatccat ctggagagat gacaagctga
     1201 ttctccaatt cttagcaatt gcttgctagt gctactgctt ctttctctaa aagataatct
     1261 tctgttgatt ggttgaatat tgctttgagg atccgtcctt cgtatttcca ttccagagct
     1321 actagatcag atttgatttc ttgaaggcta tacttgccat gcgaaatgat tactgacgcg
     1381 tatttccgaa tcttaattag cctcttcata aagttcagca tatcattgtc acttgataca
     1441 cgttcccaag gcatacaacg acggcaatct ggatctggtc ctccagtcaa ggctagctcg
     1501 gttccgtaat aaatgcacgg tgttcctttt tgtaaaaaga gaaaggctaa ggctgattta
     1561 accagttgaa catcttcatt ggccgtccac aggattcgct ctgtatcatg tgaatccaag
     1621 agattaaaca tgacctctga aatctgctgc ttgtaataca tagactctcc attgatttca
     1681 tcgatgaact ggtctgtctt cttaattcct cgtaagaaat agtccttgat actatcagat
     1741 aaaggataat tcatgacggc atggaactca tctccattta gccaaggctg agatgtatgc
     1801 cagacttctc ctaggatata aagatcagga tttttagcta aaactgcctt acgaaaatcc
     1861 ttccagaact gatggtcaat ctcattagcc acatccaaac gccaagcatc gatattaaac
     1921 tcttcaatcc aataagtcgc aacctttaaa agataattct tgacctctgg attggctgta
     1981 tttagcttag gcatatagtc ctcgaaacca aaaacatgat agggtaagtc tctcttatta
     2041 actagctttt cagttgtcac tgggaattgt tgaatatgga accaatcctt ataagcagac
     2101 tgttcaccat ttttgacgac atttttccat tgaagagatt gcgaaccaat atgattaaat
     2161 accgcatcca gcatgacttt catgccacga tgatgcgctt gatccaccag ttcccgaaag
     2221 gtctccttgt ctccaaaatg atggtcaatt tcaaagtaat ctgtcgtatt gtacttgtga
     2281 ttgcttgtag attcaaagat gggacaaaga tatagtccag taatacccaa gtcttgcaag
     2341 taatccatat gatcaataat cccctgtaaa tcaccaccaa agaaatcatc gctcttaggt
     2401 gtgacagatg aatcccagtc taaagtccct tctgggttta atagagcatt gccattggca
     2461 aatctttcag gaaatagctg ataccatacc gtatttgaaa cccagtcagg aaccttgcag
     2521 gcatcaatct catgaagata aggcaactta aatccattcc caattgcatg aagattttct
     2581 agagaatttt ccacacaccc tttatcgcca tacaaaatat tttgaccttc tgtatctctg
     2641 agctcaaaga gatactggat acgtgcaaag tcaactgaca cttcaacctg ccaatggtca
     2701 aataaggtac cagaagttat cttgaccatt tcttttgtat cctgataaaa ctcctccata
     2761 aagataaaag ggtccccata gtgcaagttg atgctttcaa tgtccccttt cttagttcga
     2821 attcgaatat ggagtttctt atccttataa agataggcat actccgactc aggcctatgg
     2881 taaatagcac tcaattccat caatttgtct cctaaagtat tcattcaaat tttacgcaaa
     2941 cgttttcaaa cttaatgaat ccagtatact atttttgtaa actatttgca aggaatgtcc
     3001 gttgttaaag gaactatctt ttaaagtata caaaaagcct taaaaaaggc tttctctata
     3061 tactaatcct ctttcggttt tgaaaatact tctactcgct gagctaggac tttgatttct
     3121 acaggtaggt tatctgattt atctccgtca acatctgact ccaattcact atctgaagag
     3181 attttaatat tacgcgcttt gatatactcg atattatcat ttgcgacaac atcccctttt
     3241 aataaatcag gaatgacgga taatttggag aatatagagg catctttcag aatcaaaatg
     3301 ttggcatagc cgtccttgtt ttcttcaaag attttcttat cagcgaagta atttgtcaaa
     3361 aggaccaaaa catggctagc ttcaccaaca taatttccat tttctgtctc aaccttaatg
     3421 ttaaagacct gatctgtcat gacagacttc atggtattta cagcataggt taaaataccg
     3481 aattttgttt tgtcctctat ttcaacattg tgaatcgcct caggcagaga accgatacta
     3541 aagatataac caaaatagtt gtcatttgct ttaccgatat caatcttatt ggttaaatca
     3601 aaatccagtt cgtcaattgc gccatcgatg tcttgattga tttccaaaag ttttgtaatg
     3661 aggttacccg taccgcctgg gataatccct aacttaggaa tgtagtctct ctcatcaata
     3721 cctgaaatga cttcattgac agttccatct ccaccaaaca caaccactgc atcatactgc
     3781 tcacgagaag cttcttcagc aaaatgtgtt gcatccagcg ctttttcggt aattttggtt
     3841 tcaacatatt caaagtattc ttttgcttta ttctccagct tttctttgta atccaaagcc
     3901 ttctcgccac agaagtaggg ttgataatta ccattgcttt tttcattgat tttatcctta
     3961 attttaaaca gaaatgttta catttcgtcg tatgcaagta aatgtaatcc tattatacaa
     4021 tgaaaataca gaaaagagaa atctgacgta ctggagatta atacgctttt attctatttt
     4081 cccatcgcct aactacatcc tttaagggtt catccaagta agaataggcc ttatccttga
     4141 tccaatcagg aataccgtaa gctgcctctg ctatgctaca agtgattgct gcgagagtat
     4201 cactgtcgcc accaagtgag atggcatttc ttatcgcatc ttcgaagtct ctactttcaa
     4261 gaaaggcgat aatggcttga gggacagttt cctgacatgt ttcgttaaaa cgatagttag
     4321 gacggatttc atctaaagtt tgagatagat tgtaatcgta ttctttttct atataatcct
     4381 taattcgtct tttacactct gtaggattgt cgttaattga ttgctcgtac tctctacaat
     4441 aaccaccaaa gtaaaaacga catagaaaga tagcatcagc tgtagccata gcgcctttga
     4501 caccttctgg atgattatga gttacctctg cagaaagact cgtaagtcct ctagatgatg
     4561 gccatatacc agttttcgca taaaaaccac agtccatgat ccaagcacat ggagaaatac
     4621 gcatagctga tccattccca aagctattat aaggctcacg gttatcgctg tttagccatg
     4681 cattaaaccg agcaccgtaa tcagcattcg gatacattct gccatatttc ttcatcgcgt
     4741 caatgaagtc gtctttttgt ccaccattca taattgcttc tgcaacagca caggtcataa
     4801 ccgtgtcatc tgtaaaaaag cagtccttcc gaaataaagg aaagtccttt gttttgatat
     4861 tgttccattc gtaaacagaa acgacaatat ctccagtaat tgctccaagc atcagattcc
     4921 tccttgttca ttttgatgct ttttatattg gttatctacc atatttattt tagaaaataa
     4981 catcctgttg gattttaaaa atttcatttt tttcaaaata gggttttacc atttctttcc
     5041 acctagctct atgaaaattg attgatttta aaggagatag gccacaattt cccaatgcat
     5101 aaccatcatt tacttcaaca acaagtgttc tgccatcgcg agtaacaccg atatctagtt
     5161 cataagctat tggcgcatct ttccaacatg atatcgcttc atcaattaca cttgcatcaa
     5221 attgtgcatg ataatcacct gtatagggtc gaacatctaa tacgcgacca tctaacacaa
     5281 aacaacgcca ttcagctatg aattctacaa cctcactaat ccatatagga tagtcgaaag
     5341 gtagaccaat acctattaaa tcatgggttc cattaacaac tcttccagta aagacttttg
     5401 aaccagcttt aggcttaata aattttcccc aattatcagg tatattcaca atctctccta
     5461 aaataccagc ataaatcttt cgaccataaa actctttaag ctcaatagga taatcataaa
     5521 ccggaacgtt taagcccatc atttttagta atgctctaat ctccattata taatctacaa
     5581 ctatatcttc acttgttaac tcttttattt cagaaaaaga ttgatataaa ataacttctt
     5641 ctccttgtaa gtaggcacct acttgagcat tgtatttatt aattgaaacc tcacttggta
     5701 atttactttg tctaatataa acaaccattt catcactcct atatcactag tgtcaactgg
     5761 cttttataat acattagttt aaaagtggag aggattttta acacagtaac tttaaatctt
     5821 tggtattaaa aaattttcac aatatttata gaaataaaat ctgtctcaaa tcagttatca
     5881 aatctagtat aaattatgag cggccactct aatactttcc ctctaaacaa gaaaaagact
     5941 tacactcaag ggttttctta cccccttcgt tataacgttt tgactctttt actagcaaag
     6001 gtatatattc acaaggaact ttggttgact attgaatctc tccaacttct tctttaacat
     6061 atccttctac atcttcaatc tctacaaaca ttgggtctaa gtgacacaag aaatgccaaa
     6121 cttcgatccc tttttttctg taaagaatcg cttcaccgtc ttcacttccg aaaaagcttc
     6181 tgtcgatttc atatccgcag ctttctaaga agtcttttgc tttacgatag ttcgtttctc
     6241 ttgtttcgac ataggcttta acttcatggt tgttaacgac atatgcatca atttttgaat
     6301 atccttcgat cactctatca tttttgaggg ataaatttga aatctctttc caaataatgt
     6361 ttacattttc ctcaggatcg aacataaatt tagataaagg aacaatattt ccgttaaaaa
     6421 taatttccat ataatccggt atgtttttag gattaaaata ctccacttca aaaccatctt
     6481 ctgtttccag agtgtatccc gggatttgag ctacaaaggc tttcccatct tctatggaat
     6541 taaatgctac taaatcttta gaataatcat tttggtacaa ttccaatata accatcgata
     6601 atctctccat tttcattatc aggctaatgt aaataagcac gtcacctgac caattcaggc
     6661 tctctgtatc atctcatcat atttcctact tactttacga gtcctatacc cagaacacac
     6721 cttatcgacc ttcggtctca cctcgtcgca ttggctgaac atctactttt acttcgctga
     6781 tgcttcaact cgtacaagca gtgataccgc ctcagcgtga tgcctcagtg ggactcaaaa
     6841 ggttcaggga accttttgag gattaattgc gtttctctaa caaactcaca cattcgacgt
     6901 gatgcgtttg aggaaataga tccaccggct ggactttctt caattcatat cccaattctt
     6961 ggtagagttt aatatcacgc gccatggttg cgacattgca ggaaatatag gcgatgcggt
     7021 ctactcctgt ttgagcgctt gctttgataa agctatcggt caatcccttt cgtggtgggt
     7081 cgaccaagat aacggttggt tgaatacctt ccttgagcca tttcttcatg gcattttcag
     7141 ccgtgtcaca gacatagtgg gcgtttgaaa tattgttcag ctgagcattt tttttactat
     7201 tctcaaccgc ttctggaatc agttcaacac cgtagacttc tttaacatgc ttggcgactg
     7261 ataaaccaat ggttccaata ccagaataag catcaataac cacgtcatct ttttttaact
     7321 ctgcaaagtc aatggctgtt tgatagagtt tctccgccat ttcagtattg acttggtaaa
     7381 aggctgggcc agcgatttgg aagtcatttc ccaacatctg gtccgtaata tagtcttgac
     7441 cataaagagt gcgccactcc ttaccaaaaa tcgcattggt attctggtcg ttgatatttt
     7501 gcatgacaga cacaatctct gggaactgct tgataacttg ttcaatcaat tggtcaacac
     7561 gaaaaacttt tggacgagtt gtcaccaaaa cgaccatgat ttgtcctgaa tagtgaccac
     7621 gacgcaccac aagattccga atcaatccag actgttcctt ttcgtcataa ggttttaaat
     7681 caaaacgacg gagcaggtct cgaagagcta ctacgacttg gtcaatgaca ggatcctgga
     7741 taaagaaatc ttcaaggggc atgaggttgt gcgaattctt acggaaaaat cctgtttcca
     7801 agacaccatt cactcgacga acgggcacct gcgccttatt gcgatacttg actggatgtt
     7861 ccataccaag cgtttcagca acttctacat ctgcaattcc agcaatcttg tagagactgt
     7921 ccttgacttg cttggtttta aacttgagct gttctggata agaaaggtgt cctaaatccg
     7981 cgattcctga acgcaggtaa gccaaatcta gatcttgatt acggtgtggt gactggacaa
     8041 ggtatttttc aacttttcca aagccaatct ttttattgac cttgaggaca cgcatgagaa
     8101 ttttttcact cggtaaagca ttctctacaa aaaagaccaa accatctacc ttggcaactc
     8161 ctgccccttc atgggtcaag tcaacaattt caacttctac aatatcattt ttctttaaca
     8221 ttcttttctc tttctattgg ccgacaaaaa agacggcaac gttacggtta ccatccatta
     8281 taccatgaaa tttcttaaga accaaaactc ttgaagaagg tgacaagggc ttgccagagg
     8341 gagcttaaga agttaccacc gtcctctagc gccttatccg catcaaagtt aaggttgata
     8401 tttttaaaac tgtcgccagc ttgtgatacg atgctttgtt taaggtcatt tagggtttta
     8461 gtgaaatctg cattgctgag gatatcactc tttgagagat tcaaggcaaa attgatgatg
     8521 atattgatct ggtttcctgt tatgacctga tcaagtttgt aattttttaa ggtatcttca
     8581 acaatcttgc ggatatcttc ttctgtcaga tttcccttgc tttctttagc tttggcgagt
     8641 cctgacttga tatcagctag ggcaacgttt aatttattag catcatagcc tgatttgtcc
     8701 ttgttttcag cattgatatc tgacaaagcc ttcaactctt cttgagccaa atctttatta
     8761 gcttgtggca ccttggctcc attagcctct agcgaatagt aaatccctgc taaagcactt
     8821 tctcctgtaa ctggaatagg ggctgctaca gtgattttgg catgttccat acccagcgtt
     8881 actgctgcgt ttcggtacat atcctgagtc accttagtga tattttctgg tgtttcaatc
     8941 ttgacctcaa gtggcgattt gtcacctagc ttttgaatct tggctgatga atacaactgt
     9001 aagctagagt cattggccac attcatgatt ttagaataaa catcaggtgt catggtcttg
     9061 agttctttgg tatctgttga ggcattgtac cccagttttt taagagtttg atttttttgg
     9121 tcttcagata gggaagaacc taggacatat tcaggttgga cataggtttc atcgataact
     9181 ttttgaacat ctgttgctgc atggacgcta ttcatagctg ttactgccca caagatcgca
     9241 gcgctagtca gaaagagttt ctttctcata gggaatttcc tcctttactt ctttagagta
     9301 atatatctat cttaaagaaa acttataaca aaaacacctg gtctagccag atattgaaaa
     9361 gagagtgaaa catttgatga tgtaaaggtt aagtcgtacc tgtctagaat aataatagtt
     9421 tcctccattt acatagagtt cagcaccgtg aaaaatggaa atggggtgaa tataactata
     9481 agtctttcca gtcgtattac caagcaaggg ggcaacagtc tcacgagagt actgtttggc
     9541 tagagccaag gtattttcct tgccattttg ggcgataaaa tcgatatagg caggtccaaa
     9601 attataggct tgaacagctg tccagatatc tacacccttc ttctgcgcca gatagagatt
     9661 gcctgtcaga gtttgaatgc cttgccgaat gctagaggca ttatcattga tggtgttggt
     9721 tgaaccactt gcagactcac tagactgcat aacatcgcct tcttttcctt ttgtttcagt
     9781 ataaatcata gcaagcacaa gctcttcgtt tgctggagtg tctttttcac tcaagatttc
     9841 tcgcaccatg ggttgatagg tcatgacttg tttgacatct tgatgaacgc ggtaagcttt
     9901 atagccagca aaaaggaaga ctgctagtac aagcactctt cgaattcgtt taaacattat
     9961 ttactttgga tatcctcgat atttttgatt aagatagagt aggttccatt ttcgttttgg
    10021 ataaactcaa cagactcggc gtcttgatag acgttattgg gaacgatgag ttcaattcca
    10081 tttgataagg agagtttttg gttttcaaat ttctttaatt ggcgactggc atcaatttca
    10141 tcaaattgaa caggttctgg tacggcttct ttgacttggt caataaagct caaacgagcc
    10201 gtcagattgt tgtcaaaaag gtcattagcc aatttctcag gtgacaattc attgctttct
    10261 tctagattgt tgaaaatagc tgatttgacc ttggattgaa attgaaaatc atctgtgtta
    10321 aaagattcgg caattctctg ggctgttttt tccagttcct tgatggattt cttaggtgaa
    10381 atcttggggg caacagctag gagattttct gaaaaatagt tcaaaaaagt cccgttgtac
    10441 ttgattcgtt tttcaatcag atggtacttg cgactctgaa gattgactac caaggcctcg
    10501 tcagcacccg ttccaaatcc aggcaggtta ttctgagtca gcttgattgg attatcaact
    10561 tctcctccga ggtgggtcaa ggtctcccgc agggcaattc gcaagaaagc gaaatgttct
    10621 acaccttctt tagaaaattg aacaaaaatc aagtcattgg tcttgagatt ttcagaaatg
    10681 ctaaactcct ctttccagag attagccagc gttactgatg tctccaacaa atcgtctgta
    10741 atatgattga agaagggatt ttcttcttcg aaaatcccag tcttggcttc atctgaatac
    10801 acatgttcaa tttttttacg caggtattct tcgatttttg gagtaatatt gagaaactta
    10861 tctgctaaga acagctcggt atcatccgga ctgaactggt gaataatggc tttcttaata
    10921 taaatgtcca taaaagtttt agtcctcgta taatgggaag gaatctgtca attctttgac
    10981 tgcacttctc acttcttcta atacagcctc attttctgca tttttaaggg ttttaatgat
    11041 gagttcagcc actttgcgac tttcttcttc accaaatcca cgtgcagtaa tggctgctgc
    11101 tccgatacga atcccacttg tcttgaatgg tgacaaggtt tcgtaaggga ttgaattttt
    11161 atttagggta atattgactt catccagcaa gttttgagca acttttccgt tttctacaat
    11221 cttagtcaca tcaacaagga agaggtggtt ttcagttccg ccagaaataa tacggaaatc
    11281 aggggcttgc aagaagacat ccgccatagc cttgctgttc ttgataacat tggcagcata
    11341 ttccttgaag gctggatcca aaacttcttt gaaggaaact gccttagcag ccacaatatg
    11401 ctccaaagga ccaccctgaa taccagggaa aatagctgaa ttgattttct tagctaaatc
    11461 ctcatcattg gtcaaaatca aaccaccacg aggaccacga agggttttgt gggtcgttgt
    11521 tgtagtgata tgagcgtatg gcactgggct tgggtgaaga ccagctgcaa ccaagccagc
    11581 gatgtgggcc atatcaacca tgagcttagc cccaacagca tctgcggttt cacgaaattt
    11641 tgaaaaatcg ataatttgag aataggctga agcaccagct acaatcagtt ttggttttac
    11701 ttcttgggct tgtttcaaga tagcatcaaa gtctaagagt tccgtttcag gatcaacact
    11761 ataagaaaca aagttgtagg tttgaccaga gaagctaaca ggagccccat gagtcaaatg
    11821 accacctgct gccaaatcca ttcccataac cgtatcacct ggctcaatca aagccatgta
    11881 agccgcacag ttagcctgac ttcctgagtg aggttggaca ttggcaaatt tagcaccgaa
    11941 aatttctttt gcgcgttcaa tggctagaga ttctaccaca tctactacat cagttccacc
    12001 ataataacgg cgtcctgggt aaccctcggc atatttgttt gtcaagatag acccttgagc
    12061 tgccataaca gccttggaaa ctacgttttc cgaagcaatc aactcgatat tgttttgttg
    12121 gcgttcttct tctttggcaa tagcattcca gagatcagca tcgtatgctt taaaatcatc
    12181 tttatcaaaa atcataggtc ttctccttta ttttgtgact agtccattag tttgatttta
    12241 caataagaaa ataaactaaa agatgcgaat aaaccgtttc tgcactttat cacaagtata
    12301 accaactttt tcataaaatg catgagctcc cagacgatga tcggcagagt ttaagcagat
    12361 aaacccataa ccacgtcttt tggcttcttg ttccaaccct tgtagtaaac ttttaccaat
    12421 accttgacct tgcgcttgag gtgaaattgc taaggctaag atattaaatc ctgctttgga
    12481 atagagtgat tcgtaaactt cagcgtggac atatccaagt aaaacatgac tagctgcatc
    12541 ctcatagcca agaaggaaat gatgggaatc ctgagataat ttagctagtt gactagctgt
    12601 gtcctctgga ctaaaagaat aacccaaagc ctcttggtta atttcacaaa tggctttcac
    12661 atcagtttct cttaaatctc ttagcatctc attcctcctc aaaagaaatc tctggcaact
    12721 gagcaagaat atcttctcgc ttaatggccc cttggcgtaa gattttcacc ttgtctccag
    12781 acaaatccaa aatagttgaa tcctgtccag ttagaaaagc atcgtcttcc agacccagaa
    12841 cttcttggtc aaaatccttc aaaatttgtt caaaggttac accacttgtc tgacctgaga
    12901 tattggcaga cggcccaatc aagggacctg tctctcgaat taaatccagt gtgatagggt
    12961 gactgggcat ccgaaatcca acagttgcaa ggtcagaatt tacccaatag ggaactcggt
    13021 cattggcttc gagaataatg gtcaaggggc ctggcaaaaa ggtctctaca agtttttgta
    13081 gataagctgg ctgattcttt gaaaagtgca agatgtcctc taaagaggca acattgagat
    13141 tgagcgcctt gtctctagga cgacgtttga gctggtaaac acagtcaact gctttttcgt
    13201 ctagcgcctt ggcaaaaaga ccataaaccg tctctgtagg tagaacgaca gctccaccat
    13261 tttccaactc ttgtctaatc ctgtccatca tcaaccacga ccatcctatc ttgaccaaat
    13321 tggtccttga gtgttcgaac tcttttttca ggaagatgtt tcttaaaaag cgcaggaaca
    13381 ctttgacctt gcttgtatcc aatttcaagg taaatcttac caccatcttt gagatagtct
    13441 tttgcatctt ccgcaattct acggtaaata gctaggccat cctcgtctgc aaagagagct
    13501 agatgaggct ccgaatacaa gacattcaag cctacctctg actcaccttc acgagagata
    13561 tagggtggat tggaaacaat tatatcatat ttttcagaaa tttctgtaaa acagtcagat
    13621 tttttaaaaa atatttgaag attttgattt ttagcatttt ctgatgcaag ctctaaggcg
    13681 tcttgggaaa tatctgctgc tgttactgac caagctggtc tgttttttgc taatgctaga
    13741 gctatggcgc cacttccagt cccgatatct aggacctgaa gattttcctc aagattttca
    13801 gttagaataa gctccactaa ctcctctgtt tctggacgag gaatcaaaac ccgttcatcc
    13861 acctttaaat gcattccata aaaatctgcc tgtccaatga tgtactgagc tggcttgtga
    13921 gttgctagtt gctggtaaat atcttctaca aattgttttt cttcctctgt tgtcacctcc
    13981 tgctggaggg caaaaataaa gtctgtaaaa gatagatttt tcagactacg atagacaaaa
    14041 gagaggcttt ccgcttcctc tccttgtctt atcaactctt cttcaaaatt tgaaaataat
    14101 tgagctaatt tcattatttg tttaattctt ctagtttttg tgtttggtca taaagcacca
    14161 aggcatccac aacttcgtcc aatttaccag acaaaatcgt atctagtttt tggagggtca
    14221 agccgatacg gtggtctgtg acacggtttt gtgggaagtt ataagttcgg attcgttctg
    14281 aacggtcacc agtaccgatt gtcgacttac gctcagcgtc ctgctcatct tgagcaatct
    14341 gagcaaagtg gtcagcaaca cgggcacgaa tgattttcat ggccttctca cggtttttct
    14401 gctgggtacg ttcttcttgc atctcaacct tgatattggt tggcaagtga acgatacgca
    14461 cggcagtcgc aaccttattg acgttctgac caccagcacc tgatgcgtgg taaatatcaa
    14521 cacgaagatc ttttggatcg atatcgtatt ctacttcttc gacttcaggc atgacaagaa
    14581 ctgtggcagt tgaggtatga acacgacctt ggctttctgt cacggggaca cgctgcacac
    14641 ggtgggcacc tgattcatac ttaagcttag agtatacaga ctgacctgaa accatagcaa
    14701 ccacttcttt aaaaccaccg acaccattca tagaggcttc catgacttca aagcgccaac
    14761 cttgggcttc cgcatacttt tggtacatag ttagcaaatc tccagcgaaa agtgccgctt
    14821 cgtctccacc agctgctcca cggatttcaa ggatgatatt cttgtcatcg tttggatcct
    14881 ttggaaggag caaaattttc agtttttctt catattcttc tttttcagcc ttggcatctt
    14941 tgagttcttg cttggccatt tcttccaagt ccgcatctcc gcctgattcc ttaatcatct
    15001 cttcggcatc gacgatattt tgaaggactt gtttatactc acggtaggct attacggtgt
    15061 cacgattgga agcttcttct tttgaaagct ccataaaacg cttggtgtct gaaacgacat
    15121 cagggtcact cagcaattct cctagttctt cataacggtc ttctacagct tgtagttgat
    15181 catagatgtt catttttctt cattctcctt attgatttca ggggcaaaat aatgtttacg
    15241 acaaaccgag atataggttt cattaccacc aatctggatc tgttctccat cgtaaacggg
    15301 cagtccatcc tgtgttcgca acaccatggt cgcctttttc ttgcaatact gacagatggt
    15361 cttgatttcg tcaatcttgt ctgctaaaag caagagatat ttggaacctt cgaacaattc
    15421 attgcgaaag tcatttttca agccaaaagc catgacgggt atgtctaact cgtctacaac
    15481 acgagctagg tcataaacat ggtggcgttt gagaaactgg gcttcatcga ccaaaacaca
    15541 gtaaggtttt tctggtaggt ctcggatata gccaaagata tccgttgttt cctcaatcgc
    15601 aagggcaggg cgtttcatgc caattcgact cgacacatag ccaacaccgt cacgcgtatc
    15661 cagagccgag gtcataatca caacaccttt tccttgctcc tcgtagttat aggccacttt
    15721 gagaatctca atcgttttac cagagttcat ggtcccataa cgatagtaca actgtgccat
    15781 gtttcttgct tcacgtccat ttctaaattt ttgctacatt ctagtatatc ataattttct
    15841 taagctttaa acggcaaaat gtggtaaaat ggaagaaatc aaaactagtg gaggaagcta
    15901 ttatgccatt tgtacgcatc gatttatttg aaggacgcac gctcgagcaa aagaaagctc
    15961 ttgctaagga agtaacggaa gcagttgtcc gcaacactgg agcccctcaa tctgctgtcc
    16021 atgtcatcat caacgacatg ccagaaggaa cttacttccc acaaggggaa atgcgtacta
    16081 aataagctag cttaagcaga attgcttagg ctttttcaat ctccaagtag cattcattga
    16141 agaaatatcc taaatttgtt acaatttgaa aagaaacttg gagaatttcc aagaaaagag
    16201 ctattaatta aaggaaacat tatgattaca cgtgaatttg ataccatcgc tgctatctct
    16261 actccactag gtgaaggggc tattggtatt gtccgcctga gcggaacaga cagttttgct
    16321 attgcgcaaa agatttttaa aggaaaagac ttgaacaagg ttgccagcca cactctcaac
    16381 tacggtcaca ttattgatcc tctgactggt aaagtcatgg acgaggttat ggttggggct
    16441 atgaagtctc caaagacctt cactcgtgag gatattatcg agattaacac ccacggtggg
    16501 attgcggtga ccaatgaaat tctccagcta gctattcgtg aaggggctcg gttggcagaa
    16561 cctggtgaat ttaccaaacg tgctttttta aacggtcgcg tagacttgac acaggcagag
    16621 gctgtgatgg atatcatccg tgccaagact gacaaggcca tgaacattgc ggtcaaacaa
    16681 ttagacggct ccctttctga cctcattaac aatacccgtc aagaaatcct caatacactt
    16741 gcccaagttg aggtcaatat cgactatcct gaatatgatg atgttgagga agctactact
    16801 gccgttgtcc gtgagaagac tatggagttt gagcaattgc taaccaatct tcttagaaca
    16861 gcccgtcgcg gcaaaatcct tcgtgaagga atttcaacag ctatcatcgg acgtcccaac
    16921 gttgggaaat ccagccttct caacaacctc ttgcgtgagg acaaggctat cgtaacagat
    16981 atcgctggga caacacgaga tgtcatcgaa gagtacgtca acatcaatgg tgtacctctc
    17041 aaattgattg atacagccgg tattcgtgaa acagatgaca tagtggaaca aatcggtgtt
    17101 gagcgttcga aaaaagccct taaggaagct gacctagttc tgctagtact aaacgctagt
    17161 gaaccactaa ccgcccaaga tcgccaactc ctagaaatca gccaagatac caatcgcatt
    17221 attctactta ataaaaccga cctgccagaa acgattgaaa cttcgaaact acctgaagac
    17281 gttatccgta tttcagtcct taaaaaccaa aacatcgaca agattgaaga gcgaatcaac
    17341 aacctcttct ttgaaaatgc tggcttggtc gagcaagatg ctacctactt gtcaaacgcc
    17401 cgtcacattt ccctgattga aaaagcagtt gaaagcctac aagccgttaa tcaaggtctt
    17461 gaactaggga tgccagttga cttgcttcaa gttgacttga cccgtacttg ggaaattcta
    17521 ggagaaatca ctggagatgc tgctccagat gaactcatca cccaactctt tagccaattc
    17581 tgtttaggaa aataagaaaa atccatgatc cttcattcgg tcatggattt tattgtcttt
    17641 attagtaatc tggtcttaag acccctgtta cagttgcctt agttgcttcg tagtcgccat
    17701 ctacgacaac cttgataatg cgtttggcat cttcttctgg tgctggaaca agaggtagac
    17761 gagtgggtcc agcttcaaat cccatatagt taagaattgc cttaactgga gcaggacttg
    17821 gataagagaa gagagcatta accttaggaa tgaatttacg ctgaattgct gcggctttct
    17881 tcatatcgct ttctgcaatg gcagtaaaca tctcgtgcat ttcatcccca tttgtatgag
    17941 aggcaacaga aataacccca tccgccccaa ggttcatggc atggaaagca tctccatcct
    18001 cacctgtata aatcaagaac tcttcaggct tgtgctcaat caagtaagcc atattagcca
    18061 aactagtaca ttctttgaca ccgataatat ttggatggtc agccaaacga agcatggttt
    18121 ctggagtcaa ttcgacaact acacgccctg gaatgttata gataataatt ggtaggtcag
    18181 aagcatctgc aatagcctta aagtgctgat acatcccttc ttgagaaggt ttgttgtagt
    18241 aaggaacaat agcaagccca gctgcgaaac caccaaattc cgctacttct ttgacaaact
    18301 caatagagtc acgcgtatca ttagtaccta cacccgcaat caaaggaacg cgtccattga
    18361 caaccttttg tacagccgca aacaactcca actcctcatc gtgggtcaaa gttggactct
    18421 cagcagtcgt tcctgcgaga agaattccat ccgtatgatg ggccaataaa tgctcaatca
    18481 aggctggaat agcatcaaag ttaatggaac catcctcatg gaagggggta ataaaggctg
    18541 taatgatttt acattctttt aaatcttgat aagacacgaa aacacctctc tatttcaaag
    18601 aaggagttca tctgaactcc taaacgatat gactatttta attcaaattt caattcggct
    18661 gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa tctgaactga gttccaagca
    18721 gcacctttga gaaggttatc tgaaacaacc cacatgtgaa ttcctttttc tgcatccaag
    18781 tctttacgga tacgaccaac aaaggtatca cgcgaaccaa ctgcattgat ggcttgagga
    18841 tagatttgat gagctacatc atcttcaaga acagcacctg ggaaggctgc gatagctgct
    18901 tttacttctt cgattggagc cacttctttt gtttcgatat aaacagactc agagtgagct
    18961 gacaagactg gaatacgcac acatgttgca gatactgcaa tgctatcatc ttccataatt
    19021 ttcttagttt ccttggtcat cttcatctct tcgtaagtgt aatcattgtc agtgaagaca
    19081 tcgatttgtg gaagagcatt gaaggcgata ggataatgtt tcttgtcacc gcctgaaggt
    19141 aagatttccg catgcaaatc acgtggtttc actccatcat tcaagacctc acgaagttca
    19201 cgttgtgtct caagaattgc tcccatacca gcacctgaaa cggcttgata agttgaaaca
    19261 atgatacggt ccaagcccca tttttggcga accggttcaa gagccaccat catttggatt
    19321 gttgaacagt tagggcaggc aatgattccg ttgtgggcat caagtgcatg agcattgacc
    19381 tctggaacaa ccaaaggaac atctggattt tgacggaaat aagatgtatt atccactact
    19441 accacgccag cttttactgc gtatggtgca tacttagctg atgtcgaacc acctgctgaa
    19501 aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg tttcttcaat cgtaatatct
    19561 tgatctttaa atttcaatga cttacctgct gaacgtgcag aagcaaggta acggatttta
    19621 tcgattggaa gtgttgattc ttccaacatt tttatcatct gagcaccgac agcacctgtc
    19681 gcgccgacta cagcaactgt atatcccata aataacctct ttcggaattt tctaaaaatt
    19741 tctataatag aagtattata ctactttttc catgaattgc aaagcttttt catcattttt
    19801 tggaaaataa aaatcccagt cgctagacta gggattaaga ggcatcttca tgtgatgagc
    19861 aggttcacac aactcatcaa ggtccgctcc tgcgttatga cctccttatg ctcaatagta
    19921 gcccgaagac tacctatcga ctcatcgcat ctactattct actaaagaga atgactttgg
    19981 tcaacagacg aaactcttta tactcttcga aaatctcttc aaacttcgtc agcgtcgcct
    20041 tgccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa acatgtttta
    20101 agctgacttc gtcagttcta tctacaacct caaagcagtg ctttgagcaa cctgcggcta
    20161 gtttcctagt ttactctttg attttcattg agtattagtt ttatttacac aggtgcataa
    20221 gaaatatatt ggaaaaattg ggggcagaca taacaaaaac ccttgtaaat caagggcttt
    20281 tctgtctatt taatgctaat tgccgggatt gaaccggcga cctcatcctt accatggatg
    20341 cgctctgcca actgagctaa atcagcttac ttaagaagta tactatattc agaaaaactt
    20401 gtcaagtttc cttagaaatt ttccatagga aaaagccagg taagaactac ctagcttatc
    20461 ttcttctatt tacttaaatc aattcgacga ccaattttac caataataat cgctccaata
    20521 atcaatgaag caaattcacc gattcctgtt gtaaaccaag taaggaagaa tggtaattct
    20581 gctacaatat ttaactctgc agcgatagta aacatggaaa ttgaaaagag gattgaaaag
    20641 aagaaatgat cttttcgaat caatccgtta aagaggtaat ccttgctata ttttgcaaaa
    20701 agccaaacac ctaaactgag gaatactaag gttgaaccac caccaacaaa gacatctagc
    20761 agtccgaagc taaagaaatt agcaatcata caaccgatgg taactccgat gatgtactta
    20821 ggattgtaaa aagccataaa gttcatcatt tctgaaatac gaaactgata agcaccatag
    20881 ctgatggcat ttagaggcgg tgtgacagtc aaaacgacgt agatagcagc gacgattgca
    20941 atatctgcaa catcacgaat agttaatttt ttcatctttt ctcctttggc ggttgcccgc
    21001 gtgtaatatg cttggtgaaa gaagctaagc accaagggtt gctttattca accctactag
    21061 tatagcacaa tagcctgctt tatgctatac ttaacacatg aaaattccta ttcaaaaatt
    21121 ttttaacaat gaaatcttag cctatctctt ttttggcctt gcgacaactc tagtttcgat
    21181 tctctcacga ctagtcattt atcaactaag tcatcaggaa ctcctggcta ctgccctagc
    21241 aaatattatc ggtatcctat ttgcctttat cacaaatgat acgattgtat ttaagcaaaa
    21301 aaagaaaaat agacttatcc gtttagtgaa attttctctt gctcgccttt ctacttttct
    21361 gttagacttg tttttaactt ttctctttgt aacccaattt cctcacatca tagggcaatt
    21421 cgtaactgaa aacattgata agataaatgc tattgaaaca ataattgcac aaatactcat
    21481 tattatcatc aattatatct tgagcaaaat ctatattttt agaaaataat gctccattta
    21541 tgagcctttt aattgccttc tataatgatt taggatacaa tgaaacacga aacattgaaa
    21601 ggaaaacagt atgttaaaaa atctaaaatc gttcttgctt cgaggaaatg ttattgacct
    21661 tgctgtcggt gttgtaattg cctctgcttt tggtgctatc gttacttcac ttgtaaacga
    21721 cattatcact cctcttattt taaatcccgc tttgaaagct gctaaagttg aacgtatcgc
    21781 tcaactttct tggcatggag tcggctatgg taacttctta agtgctatta tcaattttat
    21841 ctttgtgggt accgccctct tctttattat caagggcatt gaaaaagcac agaaactgac
    21901 tggcataaag gaagaaaaaa ctgccgaaaa aaaaccaacc gaattggaag tccttcaaga
    21961 aataaaagct ctccttgaga aaaaataatc gattaaaagg atctagcgca aagctaaatc
    22021 cttttttctt tactctttgg gtaacttgcc tgctttttca agcatttttt tgataagata
    22081 aggcatctta acattctccc gccctttttt ctcaatcagt tttttcacaa attctggcat
    22141 ttgtaaatct tcagattcag ccaaaatgtt tttcgtctcg tctgaaggaa ctaactcatc
    22201 aaaggtctct tcttctggta gaaattcctt aaactcttga ttttcattga ctctaattgt
    22261 attgaccaaa gcatcaatca aacgagaatc tgtatttggc attggtggac gatggtagtt
    22321 taccccaaat tcctgacata agtcataaca ttccacatca ttgtcaaaca agacctcaat
    22381 atgctcactg atgaaactaa taggtacaaa aatataatgg tctggatgtt ctgtctgttc
    22441 tctgagatac tccaaaacat ctggtttaat ccatggaata ccaatatcac tctcactctg
    22501 ccaagtgttg gtatattgtt ctgaactcaa gcccagtttt tcagcgacta gcttgctatt
    22561 ttcgaaaatt tggtctatat aaggatcacc aaagtccaag gcaaaaatag gcacactatg
    22621 ggctgaaaag atgactttaa agctgtcttg ctttacttct tcttctaaaa tcttagcaat
    22681 ttcatctgcc caatagttta agagcgcttc ttcctgatac cagtccttaa tgaccaaaaa
    22741 ttgaatttgt ttgctttcta aaaatttttc atagcccatg acagagtaga aagaataatg
    22801 gggctccaaa atcaagcaaa tacactgttc aattccgtct gcttccattt gaccgatcac
    22861 atctggaata aagggactgg aaaacttatt agcaaagtag acactgtatt cattccccag
    22921 cctatcttct accaaggcaa cctcttgacg ggtaattttt tgcagaggcg tgcctccaat
    22981 tcgtacataa ttatcataga gagtctgaat ctcgtggtct tggggtctca ccccacgacg
    23041 aatatttgtg aaaaaatcag ctacaccttc aaaggtaatc tcttctggtg aaccgaaggt
    23101 catcattaaa attgcttttt tcatgactgc ttccttgtga tgtttttatc aagtttattt
    23161 tatcattaat tcatcgataa gtaaacgcta acatagggac attctcaatc ttctgtcttt
    23221 tgtttttctc ttctttctat gatacaatgg aaaaaataaa ttcaaaagga gtttttttat
    23281 gacttatcca aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga
    23341 tgaacactct actactactc caagtacaca gagtcaggtt gacttcgcaa caaatctcct
    23401 aattcctgaa atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc
    23461 tattggaacc ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca
    23521 catggatact gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga
    23581 tggtggtgtg attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag
    23641 tcttgaaaaa tatccaggac aaacgctcat cacaacagat ggaacaacct tgctaggtgc
    23701 tgatgacaag tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc
    23761 tgaaattaag cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg
    23821 tgccaataaa tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg
    23881 tccactaggt gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca
    23941 aggccgtaat gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc
    24001 aattgatttt cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca
    24061 aggtttttac catctaatgg atgtgacagg tagtgttgag gaggcgcgtg caagctacat
    24121 cattcgtgat tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc
    24181 tgataagatg aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta
    24241 ctacaatatg aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt
    24301 tatggaagat ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc
    24361 taagatttcc tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca
    24421 cggacgtttt gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg
    24481 catcgtagct tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta
    24541 ttctactggt ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga
    24601 agttgattca gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctaccagt
    24661 ttcaatgtta gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcaccatt
    24721 tgcttcagca tttcttgctg gacttgtttc ttcacttgcg ctagcttttg actggatttg
    24781 atgattcaaa actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactctt
    24841 agcagaaagt tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt
    24901 actttctaaa taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag
    24961 tgtctgagga tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt
    25021 caagacatct tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc
    25081 agcttttaga ttttctactt cttctgccaa ggattttctg attccttctt catggatttg
    25141 ttccaagagt tgatttgcct tgctcaaaag actttctact tcttccttgc tatctgtcgc
    25201 agattattgg ttgccatcta ccatgtactc ctaaaacagg agagttataa tccaagatta
    25261 caaggcctta cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc
    25321 ttcgcacagc agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct
    25381 ttttagtgtg cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac
    25441 tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg ttcgataggc ttgtctttgt
    25501 agatgcttct gctatcagct agaagttgat ctacttttgc caagactgcc ttctcatcaa
    25561 aagttccagg ttgatagttg gattgcaggg atggaatctt gtttttcaaa gccgcttcat
    25621 atcccttagt ttgaaccttg atgtagtgat tgtggtcgcc atgaggaatc acaaaacctt
    25681 ctgaatcttc acttataatt cgattggcat caaaaccatg accatcttct tcctcatggt
    25741 ggacatgtag tgacggatta cttaatacag aactagaaga acttcctacc tcttccgtgt
    25801 tagagtgtga tgggggattg ttaagagatg acttaggaat atagtgatag tgatccccat
    25861 gtcttactat at
//
LOCUS       DAVDHZ010000030        25042 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000030 DAVDHZ010000000
VERSION     DAVDHZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.031"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(23..1306)
                     /locus_tag="VUR46_001493"
     CDS             complement(23..1306)
                     /locus_tag="VUR46_001493"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET5456896.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFNSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLAELKEKYRNEL
                     AAAKEEAYKDAVEGAAIDKAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(1621..2640)
                     /gene="cbpC"
                     /locus_tag="VUR46_001494"
     CDS             complement(1621..2640)
                     /gene="cbpC"
                     /locus_tag="VUR46_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET5456897.1"
                     /translation="MKILKKTMQVGLTVFFFGLLATSTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDKGEMVVGWQYIEIPGTGYRDNLLDNQPVNEIALQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYTPSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     QTGWQYLGNNWYYLRSSGAMATGWVKDGSTWYYLDAQNGDMKTGWAYVGNSWYYLRSS
                     GAMSTGWVKDGSTWYYLNASNGDMKTGWFQVNGKWYYAYSSGALAVNTTVGGYYVNYN
                     GEWIK"
     gene            complement(2658..3992)
                     /locus_tag="VUR46_001495"
     CDS             complement(2658..3992)
                     /locus_tag="VUR46_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HET5456898.1"
                     /translation="MKKTFYKKLGISIIASTLLASQLSTVSALTVISSTGEEYEVSET
                     LQKSPGTNNLSLPEISPTYGQYYKNQSEVIIGNNDLVKVKNTLQYPYSTSAYVKATFK
                     FKNADSVEIGTGRGSASFIKDNVLITAAHVVYDRKSKTEATEVEIMPAATPDSNPFGE
                     IKVKEVRYLKEFRNTDPDELTTYDLAVLILEEPIGAQLGTLGLPNNLENTKNLDVTIT
                     GYPSFNKLIKQMYTDTKLVLQDTNDFLFYQVDTLPGASGSAVYDSNNRVVGVHTNGSE
                     AEQMNYAVKLNEKALSFIYSVIQGHSIDGWKLISGTWYYYKDSTKQTGWQKINDTWYY
                     LDASGKMLTDWQKVNGKWYYFGSSGSMATSWKYVGGRWYYFDKTNGDMKTGWYKDGST
                     WYYLDPTNGDMKKGWIKVGGNWYYLNSSGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(4212..4844)
                     /locus_tag="VUR46_001496"
     CDS             complement(4212..4844)
                     /locus_tag="VUR46_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456899.1"
                     /translation="MRILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     VRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLNAGAKGYML
                     KTSSADELLHAVRKVVAGELAIEQEVSKKIEYHRNHMELHEDLTARERDVLQLIAKGY
                     ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGREDF"
     gene            complement(4858..5853)
                     /locus_tag="VUR46_001497"
     CDS             complement(4858..5853)
                     /locus_tag="VUR46_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5456900.1"
                     /translation="MKKQAYVIIALTSILFVLFLSHSLLEILDFDWTIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGKEVVQVSDPDLDASFKS
                     LSGKLNLLTEALQKSENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGVSQ
                     QALKLDREKMKIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLVEGIQILLKELED
                     KSDLRVSLKQNVTQLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDLELQLKV
                     VDNGLGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5850..6548)
                     /locus_tag="VUR46_001498"
     CDS             complement(5850..6548)
                     /locus_tag="VUR46_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET5456901.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVVAAILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRLMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETRDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6625..7635)
                     /locus_tag="VUR46_001499"
     CDS             complement(6625..7635)
                     /locus_tag="VUR46_001499"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET5456902.1"
                     /translation="MTTNRKDEHIRYALEQKSSYNSFDEVELIHSSLPLYDLNEIDLS
                     TEFAGRKWDFPFYINAMTGGSDKGREINQKLAQVAEACGILFITGSYSAALKDPTDDS
                     FSVKYDHPNLLLGTNIGLDKPVELGLQTVEEMNPLLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYELGVRTFDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQDWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELIETYTVEEVIDIVQGWKDDLRLIMCALNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(7619..8626)
                     /locus_tag="VUR46_001500"
     CDS             complement(7619..8626)
                     /locus_tag="VUR46_001500"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET5456903.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKAISIYMKGEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYCLIQETIALVEDFLVYRGQTLRPFSLEIRGKMEREGKKF
                     GLGSSGSIVVLVIKALLALYDLSVNQDLLFKLASAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFNRQKVAAWLEEENLTTVLERDWGFSILQVKPALECDFLVGWTKEVAVSSNMVQ
                     QIKQNINQNFLSSSKETVASLVEALEQGNVEEIIKQVETASQLLEGLSLDIYTPLLRQ
                     LKEASQGLQAVAKSSGAGGGDCGIALSFDVQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8613..9566)
                     /gene="mvaD"
                     /locus_tag="VUR46_001501"
     CDS             complement(8613..9566)
                     /gene="mvaD"
                     /locus_tag="VUR46_001501"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET5456904.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSSLPMDAIADAFYINGQLQNESEHAKMSKIIDRYRPVGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFQLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLVYLK
                     ENDFAKVGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREQGEACYFTMD
                     AGPNVKVLCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9548..10426)
                     /gene="mvk"
                     /locus_tag="VUR46_001502"
     CDS             complement(9548..10426)
                     /gene="mvk"
                     /locus_tag="VUR46_001502"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET5456905.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AASPWRLYEEDTLSMAVYASLEYLNIKEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQAELPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMNL
                     SAYLVIADTGVYGHTREAIQVVQSKGKDALPFLHALGELTQQAEEAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADSLVETALSHGALGAKMSGGGLGGCIIALADNLTQAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10602..14189)
                     /locus_tag="VUR46_001503"
     CDS             complement(10602..14189)
                     /locus_tag="VUR46_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001009804.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET5456906.1"
                     /translation="MNFKSRKCEENGKKVLRYSIRKHHLGVASVAVASVLFFATGVAT
                     VQADGPGVGEPVSGTPAPPSTPGSASTTSTTSTLGTSGANTGDAEIENTNIDTNTNTA
                     ASTESNGNSLQGVPGAAEVRNGNDVLGTTLGSDRAVPTDIKPEDSDGARNNEEKPNYA
                     GKVTLMKQWDVNANDPTIRKDTPREYKTGEDKLGKPAFYSSTANTFLGWSDKPSVDGK
                     IDEKNGARLFSPEDTLATAFPKGLKPDSKLYGVYTSFTKNEEPVPTGNDFRRGMILLK
                     GLKRFTINANKVKIDTKVESEDVLPNTKLSKATEDVEDEKNTRRIIDKYNPENNDTTK
                     VNEVVLKAEFEMDNSTAMTVYRNPDARGQGPVLSNSYKNNKFEIDEKKKTYTYVDLNV
                     NLDKDLVVPEKLYAEFNGYSWRPLYAIGIKKDGTKEILNVYSKDGTNLGNTKDSFNSL
                     VSNTDPKVTFGVETKGYNNITFRMILRSLNGKDSNRPESERDKRNERIAESVIKPDEG
                     KSIAETIMRNMTLKTLSSKELKTLFPDKSDEEINQMVVRIAQDKAKKLADTNGETVLK
                     VTGYVDGNVHPSAGRVGLGFFGFDLSDNLPIKKIDANILELGYVHPYKATYKFISGTE
                     GKDLPAAIEGYKPKDPKTYENTANVNAIQPTTKEYPVAEEDGKWVFKSYDAENKAVNE
                     ADVEFIGTWVFEANKYGVTYKFVSGTEGKTLPAAIEGYKPTDQNRYVDKSNVTTIQPT
                     KTEYVDTENDGKWVFKSYDAENKAVNKADVEFVGTWVFEANKYGVTYKFESGTPGKTL
                     PAAIEGYKPTDQNRYVDKSNVTTIQPTTKEYVDTENDGKWVFKSYDAENKQVNKADVE
                     FIGTWVFESNKYGVTYKFQSGTPGKTLPAAIEDYKPTDQNRYADKANVVATQPTKTEY
                     VDAENDGKWVFKSYDAESKAVNKADVEFIGTWVFVANKYGVTYKFQSGTPGKTLPEAI
                     EGYKPTDQNRYVDKSNVTTIQPTKTEYVDTENDGKWVFKKYDAESKAVNKADVEFVGT
                     WVFVANAPTPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKREPKPEPKPEPKPEPKPEPQPTPTPTSIS
                     SEDWNQGSTEVHKRDELPQTGSQQDEWLVALGGLSLLGALTVFSKKREE"
     gene            complement(14568..15596)
                     /gene="cbpF"
                     /locus_tag="VUR46_001504"
     CDS             complement(14568..15596)
                     /gene="cbpF"
                     /locus_tag="VUR46_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HET5456907.1"
                     /translation="MKIIKKLMQIALAVFFFGLLATSAVLADDADSEGWQFVQENGRT
                     YYKKGNLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPAPHEGVTIGSSLRQDIAFRPD
                     WFYFGQDGVLQEFVGKQVLEAKTATNTNKHHGEQYDSPAEKRVYYFEDQRSYHTLKTG
                     WIYDEGHWYYLQKDGNFDAGIDSLTVGELARGWIKDYPLTYDEEKLKVAPWYYLDPET
                     GIMRTGWQYLGNRWYYLRSSGAMATGWYQDGSTWYYLDNKNGDMKTGWVYVGNRWYYL
                     RSSGAMTTGWYQDGSTWYYLDNKNGDMTTGWFQVNGKWYYAYSSGALAVNTTVDGYSV
                     NYNGEWVR"
     gene            complement(15695..16384)
                     /locus_tag="VUR46_001505"
     CDS             complement(15695..16384)
                     /locus_tag="VUR46_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5456908.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQ
                     TDYDLILLNAHLGDMTAQDFAEKLSRTKPASVIMVLDHREELQDQIETIQRFAVSYIY
                     KPVIIENLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(16396..17820)
                     /gene="gndA"
                     /locus_tag="VUR46_001506"
     CDS             complement(16396..17820)
                     /gene="gndA"
                     /locus_tag="VUR46_001506"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET5456909.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFKFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(17896..19266)
                     /gene="mapZ"
                     /locus_tag="VUR46_001507"
     CDS             complement(17896..19266)
                     /gene="mapZ"
                     /locus_tag="VUR46_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET5456910.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHKDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEASSEEV
                     PSSEDILPPLPLDDEEQGLDPLLLEDENPTEMTEEAEEEQSLSRLEQEESEEKSKKGF
                     VLTALALVSVIICVSAYYVYRQVNRSTKEIQTSQSTTANQSDVDDFNTLYDAFYTDSN
                     KIALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     ETKPSSSNEARSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            complement(19279..20436)
                     /locus_tag="VUR46_001508"
     CDS             complement(19279..20436)
                     /locus_tag="VUR46_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET5456911.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWVSDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(20521..20901)
                     /gene="rnpB"
                     /locus_tag="VUR46_001509"
     ncRNA           complement(20521..20901)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VUR46_001509"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(20922..21263)
                     /gene="gpsB"
                     /locus_tag="VUR46_001510"
     CDS             complement(20922..21263)
                     /gene="gpsB"
                     /locus_tag="VUR46_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET5456912.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEV
                     FGKQILDNTDL"
     gene            complement(21333..21860)
                     /locus_tag="VUR46_001511"
     CDS             complement(21333..21860)
                     /locus_tag="VUR46_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET5456913.1"
                     /translation="MTTALVLGYSAFDLGLFSDKDPRLKLIKKAIRRDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQDMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            21927..22523
                     /gene="recU"
                     /locus_tag="VUR46_001512"
     CDS             21927..22523
                     /gene="recU"
                     /locus_tag="VUR46_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET5456914.1"
                     /translation="MVNYPHKVSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            22520..24685
                     /locus_tag="VUR46_001513"
     CDS             22520..24685
                     /locus_tag="VUR46_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET5456915.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVSYPDDDLQVASTVV
                     DVSNGKVIAQLGARHQASNVSFGTNQAVETNRDWGSSMKPITDYAPAIEYGVYDSTAT
                     MVNDIPYNYPGTSTPVYNWDRAYFGNITLQYALQQSRNVPAVETLNKVGLDRAKNFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRGAYLPWLPQAGKTGTSNYTDD
                     EIEKHIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFLVAAKVYRSMITY
                     LSEDTHPEDWTMPDGIYRNGQFVFQNGARPTWTETTSQSSSTESSSTSAESSTSQAPA
                     TSPDASTNGQNQAPNAPGANQNPAPQTPQPPQVQQQPQQ"
BASE COUNT         7066 a         5709 c         4355 g         7912 t
ORIGIN      
        1 ttgattttcg aagagtataa gattatttaa ctgttgctgt gcttgtaatc aattcaacag
       61 cttttttgat tgtgatatcg tgtttcaaca tatcagctga aagcaaactt tgtacttgag
      121 caacttccat gttgtagtct gcagccaatt gctcaacttc tttttggatt tcttcttctg
      181 aagcgtcaaa tccttcagct ttggcaactg cttcgataac aaggttagtc ttagtacgtg
      241 actcagcttc tgcttggtat tggttgtgaa ggtcttcttg agtagttcca gtgatttgga
      301 agtacatgtc agggttgata ccttgacgtt gcaagtttcc aaggaattcg tttactgaac
      361 ggtgaacttc ttcgtgaatc atttcttctg gaagttctac gatttcagcg ttttctacag
      421 ctttatcaat tgctgcacct tcaaccgcat ctttgtaagc ttcttcttta gcagcagcca
      481 attcgttacg gtatttttct ttcaattcag caagtgtttc aacttcttcg tcgatgtctt
      541 ttgcaagctc atcgtcaaga gctggaactt ctttagcttt tacttcgtgg atagttgtca
      601 cgaatttagc ttctttacct gcaaggtctt ctgcttggta gtcttctggg aatgttacga
      661 taacgtcaac agtttcgcca gctgagtgac ctaccaattg gtcttcaaaa ccagggatga
      721 attgacctga accaagtcca agtgagaagt tttcaccttt tccgccatca aattcaacac
      781 cgtcgataga accaacgaag tcgatgacaa cagtgtcgcc gttttcagca gcagcttcct
      841 tgataaccaa ttcagccaag ttgttgcgtt cgcgttcgat acgctcttca acgtcagcgt
      901 cagttacttc tttttctaca tcaactgata cttctaggtt tttgtagtca cccaatttta
      961 cttcaggttt tgtaacgact tcagcagtga taacccagtc ttgacctttt tccattgaag
     1021 ttacgtcaat ttttggttgt gcaaccactt caagaccagc ttcttttaca gctgcttcat
     1081 aagcgtttgg caaaagagcg ttcataacgt cttggtaaag tgattcttca ccaaattttt
     1141 tgtcgaagat aggacgtgga aggtgacctt tacggaaacc tggaacatta agagatttct
     1201 tcactgagtt gaagacacga tccaattctg gtttgatttg gtcttgagag atagtgaaag
     1261 tcaagacacc acggtttgtt tctttgtttt caaatgatac agacattctg tcatttctcc
     1321 ttaaaatttt ttaaatacag tctattataa cataaacgag cgactttttt caagtaatga
     1381 ctgcgctttt caatcatgct ggaagtatgg tttctccttg gttttcttta tactagattg
     1441 aaatcaaaaa gcattatata atagtgatag gaaatcaact aaagaagaaa tctttccact
     1501 acaaaaacgc atattatcaa ggttgaacac ctaataatat gcgttttttt ctattttaaa
     1561 gacttttatc cacctattat aaaaagttaa gtatccatca cagtttacaa ttagccttca
     1621 ttacttaatc cattcaccat tgtagttgac gtagtagcca cctactgtgg tattaacagc
     1681 taaagcacct gagctataag catagtacca ttttccattg acctggaacc agcctgtctt
     1741 catatctcca ttacttgcat ttaggtagta ccaagttgaa ccatctttca cccaaccggt
     1801 agacattgca cctgatgaac gaaggtagta ccaactgtta ccaacataag cccaacctgt
     1861 cttcatatca ccattttgag catctagata ataccaagtt gaaccatctt tcacccaacc
     1921 agttgccata gcacctgatg aacggagata gtaccagtta ttacctagat attgccatcc
     1981 tgtttgcata atgccagttt ctgggtctag gtaataccat ggagcaggtt tgcttctatc
     2041 aatgtcaata gtaacatgaa aatcttgagt ccaaccctta gcaacttcac caattggtag
     2101 tggattgtac gaatcatcgc caaaatttcc tagcttattt aaataatacc aatgaccctc
     2161 ttcataaatc caacctgtct ttacagcata attattatca aaataataag ttctcttttc
     2221 agcagatgga gtatattgtt caccgtatac ttttcctgtg ttttcagacg tttttgcctc
     2281 tagtacttgt ttatctgttt gttctagcaa agcaccatct tgtccaaaat agtaccactt
     2341 ctcctgaagg gcaatttcat taactggttg gttgtctaat aaattatcac gatagcctgt
     2401 cccagggatt tctatgtatt gccaaccaac taccatttct cctttatcac caaaatagta
     2461 agttttaccg tctattttat gccaatagat tgctttatga tcatctttta cataatattt
     2521 tctattatcc ttatcaacaa atcggccacc tgtggtattc gcaaatactg tacttgtcgc
     2581 tagcaaacca aagaaaaata ctgtcagtcc aacttgcata gtttttttca aaattttcat
     2641 ctatatatcc tccaatatta aatccactca ccagatgagg cgaaattata cactttacca
     2701 tcgatagttt ggctacctgt aaccattgct ccagaggaat tgagataata ccagtttcct
     2761 cctactttta tccaaccttt tttcatgtct ccattagtag gatctagata gtaccatgtt
     2821 gagccatctt tataccaacc agtcttcata tcaccattgg tcttatcgaa ataataccat
     2881 cttcctccta catatttcca acttgttgcc atagaaccag aggagccaaa ataataccat
     2941 tttccgttta ctttttgcca atctgtaagc atcttacctg aagcatctag atagtaccat
     3001 gtatcattta tcttttgcca acctgtttgt ttcgtactat ccttataata ataccaagta
     3061 ccactaatca atttccaacc atcaatagaa tgtccttgaa taacagagta gatgaaagat
     3121 agagccttct catttaactt aacagcataa ttcatctgtt ctgcctcact cccattggta
     3181 tgaactccga caaccctatt attagaatca tatactgctg aaccactagc accaggtaaa
     3241 gtatctactt gatagaataa aaaatcattt gtatcttgaa gtaccagttt tgtatcagta
     3301 tacatctgct taattaactt attaaaagaa gggtatcctg taattgttac atctagattt
     3361 ttagtatttt ctaaattatt tggaagtcct aacgtcccca attgagcacc aatcggttct
     3421 tccaaaatta aaactgctaa gtcataggta gtaagctcat ctggatcagt atttctaaat
     3481 tcttttaaat aacgaacttc tttgactttt atttcaccaa atggattact atctggagta
     3541 gccgcaggca taatctctac ttcagtcgct tctgttttgg atttacggtc ataaacgaca
     3601 tgagctgctg taatcaaaac attgtctttg ataaaggaag cacttcctct acctgtacct
     3661 atttctactg aatcggcatt tttaaatttg aatgttgctt ttacataagc tgatgtagag
     3721 taaggatatt gtaaagtatt ttttacctta actaaatcat tgttaccaat aatgacttct
     3781 gactgatttt tatagtattg accataagtt ggcgaaatct caggaagtga caaattatta
     3841 gttcctggac ttttctgtaa tgtctcactt acctcatatt cttcacctgt actagaaata
     3901 acagtcaaag cagatactgt cgataactgg ctagccaata aagtactcgc aataattgaa
     3961 atacccaatt ttttataaaa agttttcttc attattctat cctcctaatg taattatagc
     4021 ataccattct aaatttctca atctactata gaatcaagaa atctaccgcc ttctttaaat
     4081 atcctctatt atgacataaa cgagcgactt ttttcaagta atgactgcgc ttttcaacca
     4141 tgctagaggt acttgctcac ttctttggta ctcaactcaa tcatttcctc aatattattc
     4201 ttatataaca attaaaaatc ttcccgcccc accaagtggt gctgaaaggc atagactgct
     4261 gcctgagtgc gatcactgac ctcaagctta gcaaggatat tggacacatg ggtcttgacc
     4321 gtcttaagag agataaaaag ttcatcagcg atgcgctgat tttcatagcc cttggcgatg
     4381 agttggagaa catctcgctc acgcgcagtt aggtcctcat gaagttccat gtgatttcgg
     4441 tggtattcga tcttcttgct gacctcttgc tcaatggcca actctccagc aaccacctta
     4501 cggacagcat gaagcaattc atctgcacta gaagtcttga gcatatagcc tttagcacca
     4561 gcattcaaaa ccggcatgat tttttcattg tccaagtaag aagttacaat caaaatcttg
     4621 gcttcaggcc attctttaag gatagccaag gtcgcgtcaa ttccattcat ctcaggcatg
     4681 acaatatcca tgacaatgac atctggacgc acttccaagg ccaagtcaat accttgagac
     4741 ccattggacg cctcacccac aacttctaca tcatcttgga ggtcaaagta gcttttcaag
     4801 cccaatcgaa ccatttcatg gtcatctact agtaaaattc tcatctttac tcctttatca
     4861 ttccttatcg agcaagggaa tacgaatatc aactgccagc ccttgcttgg gagctgttaa
     4921 taactgaacc gtccctgcca tatcttcaac tcgctctttg atattgcgta atccataact
     4981 caagtcgtct aaactcccta actgaaaacc aagcccattg tccaccactt tcagctgcaa
     5041 ttcaagatcc gtctgataga gatagacatc caaacaagag gcctgggcat gacggagggt
     5101 attgctgatc aactcttgca ggatacggaa gatatgctcc tcgattttct tgggcaattg
     5161 cgtcacattt tgcttaagac taactctgag atcactcttg tcctcaagct cttttaagag
     5221 gatttggatt ccctcaacca gactcttctg ctccagctca actggtcgca aatgcaagag
     5281 caagactctc aagtccttct gggcagtttc taaaatagct gtgacactct gcaactggat
     5341 cttcatcttt tctctatcca atttcaaagc ctgctgactg acacctgaca aaatcatgtg
     5401 ggccgcaaac aactcctgac tgactgtatc gtgcaaatcc ctagcaatcc gcttccgttc
     5461 cttctcgatg atttcctctt cctgatcaag actgtgattt tcagactttt gaagcgcttc
     5521 tgtcaagagg ttaagcttac ctgacaagga cttgaaactg gcatccaaat ctggatcgga
     5581 aacctgaacc acttctttcc ctgccaacaa acgcttgaga ttagcctgca tttttcttag
     5641 agaaagctct tcaatacctc gccaaaatag ggctaagaga caggtcatgg acatgctgaa
     5701 taccaacaac aaaaagacaa atttttctgt tttttcgaca tcatgcaaga aaatagtcca
     5761 gtcaaagtca aggatttcca gcaagctgtg ggacagaaat aagacaaaca ggatggaggt
     5821 gagagcaatg attacataag cttgtttttt catcctctga ccacctcaac atctccaatc
     5881 atagtggtca agaaaatctt gacactcttg ttactcttaa gatagtctct tgtttcttga
     5941 tgatagtgtt catttcggag ggctcgcttg ggctggttga aaaaagtcaa atcaccatag
     6001 agacagttaa cgctgagact gacttccaca tctacaggta cgatgatttt ggtcgttcct
     6061 accatctttc tgaggataat gacattgtca tgattggtta agatgaccct ctccagatga
     6121 atggtgtcct tacccatgag acgaaagaga ttgatatcat caaactggca agtctggtag
     6181 cttgaaaaat gatggagatt tccaaaccaa cgatttttct ccttcttaac cgttaccacc
     6241 tcttcaaaaa ccaaattggt ctgctctttt tcctggttca tcatcggata aagaagaaag
     6301 aggctataga tgaccgcaac aaaaatagct agaatcacaa aaggattgag catgacgata
     6361 aaaaagaaga gaatggctgc caccactaaa agaagattat ttccctcttt accagtgtaa
     6421 tagcgaatca aaagcaaaaa gaggaataaa atcagcagaa aacgcgaaaa atgctctgat
     6481 accatcaaaa tcagagctcc tgtcaacaga caggcttcga taaataaaaa gattttaaat
     6541 tttctcatag gttgatcctc tctcttctat tttatcacac ttcaaaaaag ccacctcggt
     6601 ctgaagatgg aaaaaaggcg gtgattacgc ctttttcatc tgatcttttg cttcttttaa
     6661 ttttccatat agaagatagt ctactttttg cagatctgct atagtggcac aattaagggc
     6721 acacataatc aaacgcagat cgtctttcca gccttgaaca atgtcaatca cttcttcgac
     6781 tgtgtaggtt tcaatcaatt ccagaacggt tcgtgacagc cctacagcct ttgcgccaaa
     6841 gaccaagcac ttaatcatat ccagcggatt gcgaacgcct ccactgacca agagttcgac
     6901 cttgtctttc cagtcttggg cattgagaag ggcctgcatg gtggactgcc cccattgatt
     6961 gaggtagtca cgttgaccac tgcgacgatt ttcgatataa gcaaagctgg tgccaccacg
     7021 acctgacagg tcaaaggttc gaacgcccaa ttcataggct ctctcgatgg tcttggcatc
     7081 cattccaaag cccacttcct tgaggacaat cggaacaggg atttgtttac tatagtctgc
     7141 cagatgcgat tgccagcttc tgaacttcct ttctccctct ggcatcagca attcctgcat
     7201 gacattgaca tgcacttgca agagaagagg attcatctct tctacagtct gaagacctaa
     7261 ctcgacaggc ttgtctaatc caatattggt tccaagaagg agatttggat gatcatactt
     7321 gacagaaaaa gagtcatctg ttggatcctt gagggctgcg ctataagagc ccgttataaa
     7381 caaaatacca caggcttccg ctacctgagc cagcttttga ttgatttctc ggcctttatc
     7441 acttccacct gtcatggcat tgatataaaa aggaaaatcc cactttcgac ctgcaaactc
     7501 tgtagacaaa tcaatctcat tcaggtcgta aagaggcaag gaagaatgaa tcaactccac
     7561 ctcatcaaag ctattatagg aacttttctg ttcaagggca tagcggatgt gttcgtcctt
     7621 acgatttgtc gtcatgtcct atcctttctt ggtataagag ctcaatcccc agatcggccc
     7681 aacgattttt taaggtttca gttgattgca catcaaaact caaggcaatc ccacagtccc
     7741 caccaccagc accgctactt ttggcaacgg cttgcaaacc ttggctggct tcttttagct
     7801 gtctgagcaa aggcgtataa atatctaaac tcaagccttc taagagctga ctggctgttt
     7861 ctacctgctt gatgatttct tctacattcc cctgctccaa ggcttctacc aaagaagcca
     7921 ccgtttcttt tgaggaactt aaaaaattct gattgatatt ttgcttgatt tgctgaacca
     7981 tgttactaga cacagctact tccttggtcc atcccactag gaaatcacat tctagggcag
     8041 gtttcacttg taagatggaa aagccccaat cacgctctaa aactgtcgtc aagttttctt
     8101 cttccaacca agcagccacc ttctggcgat taaatgactg gtagagaacc aaatcctctg
     8161 ctacaataca ggcaaggtcg cccatggaac cattgtctcc tcgcttgagc aagacagcac
     8221 tagccagctt aaacaagaga tcttgattaa ccgaaagatc atatagagca agcagagcct
     8281 tgataaccaa gacaacgatg ctaccgctag aacctagacc aaactttttc ccttctcgtt
     8341 ccatttttcc acgaatttct agagaaaaag gtcgcaaggt ttgcccacga taaacaagga
     8401 aatcttccac taaagcaatc gtttcttgaa tcaagcagta gtcaggattt ggcgtcaaat
     8461 ccactgcgaa atcaaacata tccgaataga tacgataact atctgaaaaa gcaatctcgc
     8521 ccttcatata gatggagata gcctttatca aggccaactg ccctggctct aaaatagcat
     8581 attcacctgc ccaatagagc tttccgcaag ttttaacagc aatcatcttg gctcaaatcc
     8641 tttgtttttg acacaatcaa gcgataacgt tgaccgaaga tttctgataa atgctccaag
     8701 tctttctctt gacagaggac tttgacattg ggaccagcat ccatagtaaa gtagcaggct
     8761 tccccttgct cacgaagctg gcggacaaag tccatggctt catagcttgc atcggtcaga
     8821 taagaaaagg ctggtgatgc tgttttggtc gtagcatgca tagccagggc atttttctcc
     8881 gttaattccc caaccttagc aaaatcattt tctttgaggt aaaccagcat atcctgataa
     8941 tccttctcag actgacgcac ccagtcatca aaggtcgtcg aggtttccac acaaagtttc
     9001 atcccatcac gactagagat tggttttttc ttgtcttcta gcaccaacat aatcatagct
     9061 agtttcaggt ctgtctctac agggtaaatt tctccgctat ccttgtccca agcacctagt
     9121 ggtccataaa aactccgaga agaagatcct gaggcaaact tagcctcctg tgccaactga
     9181 cttctatcca atccaagctg aaaataagca ttacaagcct tgaccaaggc agacaaacca
     9241 ctagaacttg aggacagacc cgctgccgta ggcatattgt tttgagtatc gatacggaca
     9301 aatccttctc caactggacg gtagcggtca ataatcttac tcatcttggc atgctccgac
     9361 tcattttgta gctgaccatt aatataaaag gcatcagcta tcgcatccat cggtagagat
     9421 gacaaagtcg tctccgtgta catattttcc aaagtcagag aaatactgct agtagcaggc
     9481 accatctctt tttctttttt ctttccccaa tatttgataa tagcaatatt tgcgtaggaa
     9541 cgtactgtta caggctctct atccatgtct gaacagctcc tttctcttct aatctttctg
     9601 ctagttcttg agcttgtgtc aaattgtctg ccaaggctat gatacagcct ccaagaccac
     9661 caccactcat tttggcaccc agagcaccat gactaagagc tgtttcaacc aaagagtctg
     9721 cctcagggct actgacacca atttctttta aatgtaaatg tgcttgactg aggatttgtc
     9781 ccaatccttc agcatctttt tgtgaaatcg cttcttctgc ctgctgggtc aattctccca
     9841 aggcatgtaa aaatggtagg gcatccttgc ccttactttg aaccacttgg atggcttcac
     9901 gagtgtgacc ataaacgccc gtatctgcaa tgaccaaata ggcagataaa ttcatctcaa
     9961 gctctgtaaa tcctacattc ttaataaagc gaataggctg gtcactgaga caggtcttag
    10021 catccaaacc actcggattc atatgggcaa tcatttccgc ccgattgacc aagatttcta
    10081 atacatcatg aggcagttct gcctgatagt agtcaaatac cgcacgaatg gccgctatgc
    10141 tgatagctgc tgacgaaccc attccccgtt tttcagggat agccgagtca atctcacagc
    10201 gaatgcaggc ttctttgata ttcaaatact ccagagaagc ataaaccgcc atggacaagg
    10261 tatcctcctc atagagacgc caaggacttg cagcagggac caccttacaa gtcacctcca
    10321 cctctaaaag aggcagggaa atggcaggat aaccgtaaac gaccgcatgc tcccctatta
    10381 aaattatctt actatgtgcc tgaccgacac caactttttt tgtcatattt tccttttact
    10441 agacgaaaaa gccgtctcat tttttcatac aagtattgct tctctcctat ctattttatt
    10501 atattttcac aaaaaaagcg attgtttcca ttcacaatcg cttttcccat tataaggata
    10561 tatttacatc attttattat ttaaacgatt tctagcatat cctattcttc tcgtttttta
    10621 gaaaataccg tcaaagcacc taggagagat aagccaccta gagctaccaa ccattcatct
    10681 tgttgactac ctgtctgagg tagttcatcc cgcttgtgca cttcagtact tccttgattc
    10741 caatcttctg aagaaattga ggtaggagtt ggtgttggtt gcggttctgg ttttggttca
    10801 ggcttaggct ctggttttgg ctccggctta ggctcccgtt ttggttccgg ttttggctcc
    10861 ggttttggtt ccggtttagg ctctggctta ggctccggtt ttggttccgg ttttggttcc
    10921 ggcttaggct ctggttttgg ctccggctta ggttctggct taggctccgg cttaggctct
    10981 ggtttcggtt ctggcttagg ctctggtttt ggctccggct taggctccgg ttttggctcc
    11041 ggcttaggct ctggtttcgg ttctggctta ggagtcggtg cgttagccac gaatacccat
    11101 gttcctacaa actctacatc tgctttattt actgctttac tttctgcatc gtatttttta
    11161 aatacccatt ttccatcatt ttctgtatca acatactctg tttttgttgg ctgaattgtt
    11221 gttacatttg atttatctac ataacggttt tggtctgttg gtttatagcc ttctattgct
    11281 tctggcaatg tcttacctgg tgtcccactt tggaatttgt atgttacacc gtatttatta
    11341 gccacgaata cccatgttcc tataaactct acatctgctt tatttactgc tttactttct
    11401 gcatcgtagc tcttgaatac ccatttacca tcattttctg catctacgta ctctgttttt
    11461 gtcggttgag tcgcaactac atttgcttta tctgcataac gattttggtc tgttggttta
    11521 tagtcttcga ttgctgctgg caatgtctta cctggtgtcc cactttggaa tttgtaggtt
    11581 acaccgtatt tattagattc gaatacccat gttcctataa attctacatc tgctttattt
    11641 acctgtttat tttcagcatc gtagcttttg aatacccatt tcccatcatt ttctgtatca
    11701 acgtactctt tagttgttgg ctgaattgtt gttacatttg atttatctac ataacggttt
    11761 tggtctgttg gtttatagcc ttctattgct gctggcaatg tcttacctgg tgtcccactt
    11821 tcaaatttgt atgttacacc gtatttatta gcttcgaata cccatgttcc tacaaactct
    11881 acatctgctt tatttactgc tttattttca gcatcgtagc tcttgaatac ccatttccca
    11941 tcattttctg tatcaacata ctctgttttt gttggttgaa ttgttgttac atttgattta
    12001 tctacataac ggttttggtc tgttggttta tagccttcta ttgctgctgg caatgtctta
    12061 ccttctgttc cactaacgaa tttgtatgtt acaccgtatt tattagcttc aaatacccat
    12121 gttcctataa actctacatc tgcttcattt actgctttat tttctgcatc gtagctcttg
    12181 aatacccatt taccatcctc ttctgcaact gggtactctt ttgtagttgg ttgaatcgca
    12241 tttacattag ctgtattttc atacgttttt gggtcttttg gtttatatcc ttctattgct
    12301 gctggcagat cttttccttc tgttccactt atgaacttat atgttgcttt ataagggtga
    12361 acataaccta gttctaaaat attagcatct attttcttaa taggtaaatt gtcagacaaa
    12421 tcaaaaccaa agaaaccaag ccctactcga ccggcactag ggtgaacatt tccatcaaca
    12481 taacctgtta cttttagaac tgtttcacca tttgtatctg ctaacttttt ggctttatct
    12541 tgtgcaatac gaacaaccat ctgattgatt tcttcatcac tcttatcagg aaatagagtt
    12601 ttaagttctt ttgatgaaag agttttaagt gtcatattac gcataatggt ttcggcaata
    12661 gattttcctt catctggttt tataacactt tcagcgatac gctcattacg tttatcacgt
    12721 tcactttctg gcctattact atcctttccg tttaaagatc taaggatcat cctgaatgtt
    12781 atattattgt agcctttagt ttcaacacca aatgtcactt taggatctgt attactaact
    12841 aatgaattaa agctatcttt tgtatttcct aaatttgttc catcttttga ataaacattt
    12901 agaatttctt ttgttccatc tttcttaatt cctatagcat ataagggtct ccatgaataa
    12961 ccattaaact ccgcatatag tttttccgga acaactaaat ctttgtctaa attcacattc
    13021 aagtctacat atgtgtacgt ttttttcttt tcatctattt caaatttatt atttttgtat
    13081 gagtttgata aaacaggtcc ctgtcctctt gcatcaggat ttctgtaaac agtcatcgct
    13141 gtactattat ccatttcaaa ctcagctttt agaacaactt cattcacttt tgtagtatca
    13201 ttattttccg ggttatactt atcaatgata cgacgtgtat ttttttcatc ttctacatct
    13261 tctgttgctt tgcttaactt agtattcggt aatacatctt ccgattcaac tttcgtatca
    13321 attttaacct tgttagcatt gatggtgaat ctttttaagc cttttaagag aatcattccc
    13381 cttctaaaat cattacccgt tgggacaggc tcttcattct tggtaaagct tgtgtaaaca
    13441 ccatataact ttgaatctgg ttttaaacct tttggaaagg ctgttgctaa ggtatcttct
    13501 ggtgaaaata gtctagctcc gttcttttca tcaattttcc catctactga aggtttgtca
    13561 gaccaaccaa gaaaagtgtt ggcagtacta gagtaaaatg ctggctttcc taacttatct
    13621 tcccccgtct tatattccct aggcgtatct tttctaatag tagggtcatt tgcgtttaca
    13681 tcccactgtt tcataagtgt tactttacca gcatagttag gtttttcctc attatttctt
    13741 gctccatcgc tatcctctgg cttaatatct gttggtacag ctctatcact acctagcgtt
    13801 gtaccaagca catcatttcc atttcttact tccgctgcac cagggactcc ttgaagagag
    13861 tttccattac tctcagttga tgcagctgta tttgtatttg tatctatatt tgtattttct
    13921 atttctgcgt caccagtatt agcaccagaa gtgcctagtg tgcttgttgt gcttgttgta
    13981 cttgctgaac ctggtgtact tggtggggct ggtgtgcctg atactggttc gcctactcct
    14041 ggtccatccg cttgaacagt cgccacacca gttgcaaaaa acaacaccga agctactgct
    14101 acactagcta ctcccaaatg atgttttcta atagaatagc gtaaaacttt tttcccgttt
    14161 tcttcacatt ttcttgactt aaagttcatt ttcaacctca tttctttttt acaaatgggt
    14221 acttataccc cccccttaaa tatttaagta tttaaagaag gttcgatttt taagcctaaa
    14281 attgtaattg ttatggtgct ttcaaaaaaa cacttgatat tacactaaca ttatatacct
    14341 ttttctaaaa catgtcatgt aaaattgggc aaaaactcaa ttttgttaaa aataagtaaa
    14401 taagtaaatc tttccacaat aaaccgcata ttatcaagtt tttgccaatt tttttgacgc
    14461 ctgataatat gcggttttct gattttaaaa actttttatc cagtatcact tcgtgaagct
    14521 gcactcttac ttaaaattta tctcaaatta caaaatacta tcattattta tcgaacccat
    14581 tcgccattat agttgacgga gtagccatct acagtggtat tcactgccaa agcacctgaa
    14641 ctgtaagcat agtaccattt gccattgacc tggaaccagc ctgtcgtcat atcaccattt
    14701 ttattatcta agtaatacca tgttgatcca tcttgatacc aaccagttgt catagctcct
    14761 gatgaacgaa ggtagtacca acggttacca acatataccc aacctgtctt catatcacca
    14821 tttttattat ctaaataata ccaagttgaa ccatcttgat accaaccagt tgccatagct
    14881 cctgatgaac ggaggtagta ccaacggtta cctagatatt gccatcctgt tcgcataatg
    14941 ccagtttctg ggtctaggta ataccatgga gccactttaa gcttctcttc atcataggtt
    15001 agaggataat ccttgatcca accacgtgct agctccccaa ccgttaaact gtcgatacca
    15061 gcatcgaaat taccatcctt ctgtaaataa taccagtgtc cctcgtcata aatccaacca
    15121 gtttttaaag tgtgatagct acgctgatct tcaaaataat agactcgttt ctctgctggg
    15181 ctatcatatt gttccccatg atgtttgttg gtatttgtag cagtttttgc ttctaaaact
    15241 tgcttgccaa caaattcttg tagtacccca tcttgaccaa agtaaaacca atctggtcta
    15301 aaagcaatat cttgccttag agaagaacca atcgtaaccc cttcgtgtgg agcaggtata
    15361 tattgccagc cgacaaccat ctctccagat aaagaatcaa aataatagta cttaccatca
    15421 atcactcgcc agtaggtttc tttgaggttc cccttcttgt agtaggttct accattttct
    15481 tggacaaatt gccagccttc tgaatcagca tcatccgcca atactgcact tgtcgctagc
    15541 aaaccaaaga aaaagactgc taatgcgatt tgcatcaatt tttttattat tttcattaga
    15601 cgtatcctcc ataactgatt gtagcaaata caaaatcgca tgtcaacatt taaagaactc
    15661 atataaaaag cagttacata actgcaactg ctttctattc ttgcatggtg taaccaacac
    15721 cacgtactgt tttaatgtag cttttttgac cttttacatc aagcttgcta cgtagataac
    15781 ggatatagac atccacgata ttggtttcgg tcgcactttc atacttccag acactttcca
    15841 acaactgctc acgagtcaga actttcttgc ttcccataag agtagccaaa aggtcatact
    15901 cacgacgggt cagagcaatc atttcctcgc cacgataaac ggtatgatgc tctacatcca
    15961 tacgcagatt gcggtaagac gttggaacct tcatctgact acagtgttgg tcgatgaagt
    16021 cccgacctcg gaaaatcgct gaaatacgag ctaccagatt ctcaataata accggcttat
    16081 agatgtaaga aacggcaaag cgttggattg tctcaatctg atcttgcaat tcttcacgat
    16141 ggtccaagac catgatgacc gatgctggct tagtccgact cagcttctct gcaaaatcct
    16201 gggctgtcat atcccccaga tgagcattca ataaaatcaa gtcatagtct gtctgaagag
    16261 ccatggagag ggctttttgc ccctcctcaa cctgatcgac tcggtattgc tctttttgga
    16321 gttccaaact taaaaagtga gctagatttc gttctttctc aagtaataaa atccgtttcc
    16381 ccatggcaga cctacttatt tttcgtcata ccaagagtag tggaaggttc cttctttgtc
    16441 tttacgttgg taagtgtggg caccaaagta atcacgttgc gcttgaatca agttagctgg
    16501 aaggtcagct gaacggtagc tatcaaagta agtaatagct gctgagaaag ttggcactgg
    16561 cacaccagct tgaacagcaa gagctacaat atcacgcact gcttgttggt acttagcagt
    16621 aacatccaag aagtactcat ccaaaagaag gtttgcaagg tctgcatcac ggttgtaagc
    16681 atctgtaatc ttttgcaaga aacgagaacg gatgatacag ccatcacgcc agatagatgc
    16741 gatgtccgca aatggcaagt tccagttatt ttctttagaa gctacacgca attgcgcaaa
    16801 accttgtgcg tatgaaatga tttttgagaa gtaaagggct tgacggatct tttcaatcaa
    16861 ctcagccttg tctccttcaa atttgaaggc agctggtttt ggaagaacct tgctagcatg
    16921 tacacgttct tctttataag tagagatgta acgtgcaaat actgactcag tgatgagtga
    16981 caatggcaca ccaaggtcaa gtgatgattg actagtccat ttaccagttc ccttgttacc
    17041 tgcagcgtca aggatgtagt ctacgattgg tccatcttgg ccttcatcgt ctttacggct
    17101 caagatatca gctgtgattt cgatcaagta gctgtccaat tcacccttgt tccactcagt
    17161 aaagatttca gccatgtctt ctgcagaaag gcctagcaag tgttgcatca agtcatagct
    17221 ttctgcaatc aattgcatgt caccatactc gataccgttg tgaaccattt tcacatagtg
    17281 accagctcca tcaggaccga tgtaagtcac acatggttta ccatcttctg gtgctttagc
    17341 tgagatttct tcaagaacat ccgcaaccaa ttcgtaggct tctttttgtc caccaggcat
    17401 gatagaagga ccttcaaggg cacctttttc accaccagaa accccagtac cgataaagtt
    17461 gatacctgag tttgccaatt cttcattacg acggatggta tctttgtaga aagtatttcc
    17521 accgtcaatc aagatatcac ccttgtcaag gtgtggaaga agggcttgaa ttgtagcatc
    17581 tgtaccaggt cctgcttgaa ccatcaacat gatacgacga ggtttttcga ttgagtttac
    17641 aaaactttca acgtcatagc ttggcacaaa gttcttttca ggatggcaag caattacatc
    17701 ttccgttttt tctttactac ggttgtaaat agcaactgtg taaccacgag attcaatatt
    17761 aagggcaagg ttacgaccca ttacggccat acctacgaca ccaaagttag cttttgtcat
    17821 ttgacactcc tcttgtttga tttgttttat tttatcattt ttacttttga aaagaaagaa
    17881 ttttgtaacg actgcttagt agtccaagtc atccgcatga ccagcgccat ttccgacaaa
    17941 gtagcctgtc ttacagttaa gggtaaagag ataggttcca tctggcttgt agagattata
    18001 ataaccattg ccgttaacga tattgacacg ttcaaggata tattggtctc cagtgatata
    18061 gccacgtgaa cgtgaagtag ctagaatttg ttccaagaca ccatccgcaa aatcccaggc
    18121 agagttgtta ctatcatcaa tagcagactg attataggca acacgactgg cacttctttg
    18181 aacagcaacc cctgcactcg agagacccat attgacttca ctgcgactac ttctagcctc
    18241 atttgaacta cttggttttg tctcactagt cgtatttgaa cttgcttgac ttgagctaga
    18301 gctagaagta cttgtttgct ggctcttacc aaggctgata gccttatcta gcactttatc
    18361 aagctccgta tttccagttt taatatctgt aaatttagca tccgatttgg ctttggcatt
    18421 ggtatccaac acaccatcaa caatagctgg tttttcaaat tgtgcattga catcttgaat
    18481 ggccttgatt tgcgttgcta gactatcata tttagatttg gcaagcgtat gttcacgact
    18541 accttccagc ttatcaagta aggttttaag ttgacttagt ttatcaaact ggctgttttt
    18601 caaagcaatt ttattgctat ctgtgtaaaa ggcgtcataa agtgtattaa aatcatccac
    18661 atccgattga ttggctgtag ttgattgaga agtctgaatt tccttggtcg agcgattcac
    18721 ttgacgatag acataataag cactgacaca gataattact gatacaagcg ccaaagcagt
    18781 taaaacaaag ccttttttgc ttttctcttc tgactcttct tgttccagac gagaaagact
    18841 ctgctcctct tccgcttctt cagtcatttc tgttggattt tcatcctcta gcaatagagg
    18901 atccaagcct tgctcctcat cgtccagagg taagggaggt aagatgtctt cagaagatgg
    18961 aacttcctcc gaagaagctt ctgactcctc tacagcctca cgcatctctt gaattaaatc
    19021 atccagactc tgagtttcaa ctaactcctc ttttttgtat tgacgagtcg caaacttatc
    19081 tgcttcgatt tcatctttgt gttgtttgac atacttgtcc aaaatggaat cctcaggcaa
    19141 gactcctgct tccacttcct catttttacg aatagcttga ccaactgtta gctcttttgc
    19201 ttcatcaaaa tcaaattgcg gttcttgacc ttctttttta tgacgatttc gtcttttttt
    19261 actcatgagt atccctttct attttacctc ttgccgtttg acacgctgac caaaatattg
    19321 atacagatcc actttcaagg ttccgttgta taacttacgc ttcttatctg cttggctacc
    19381 atacttgctt tcaaaggctt catcactagt caagataaat ttgctccaag ttttcagtgg
    19441 tgcaaatact tgacccatct cagcataaag cttggtcacc cctgcatcat ctgataaacg
    19501 ctccccgtaa ggaggattgg agatgattac accattgatt ttatcggaac gtaaatcctg
    19561 cacgcgcatc tgcttaaagg taatgtctcc tgcaacacca gctgcctgag cattagcttt
    19621 agcaatttct accatgcgag catcgatatc acagcccata atatccagtt ccagctcacg
    19681 gtctactttt ttggctgctt ctgtgcgcac ttcctgaatc aagcggtcgc tgacccagtt
    19741 ccactcctca aatgcaaaag agcgacgaag tcctggtgcc atctttcgag caatcatgac
    19801 tgcctcaata cagaaagtcc ccgaaccaca ggtcggatca atcaaaggct tatctggata
    19861 ccagttagaa agttgtaaaa tggctgctgc catgttttcc ttgatagggg ctcccccttt
    19921 ttcggtacga taaccacgtt taaagaggct agaccctgtc gtatcaatca tgacagttgc
    19981 cacatctttg agaatagaga cctcaatctt aaactctggg ccattctcca tcaaaggaac
    20041 cccttctggg cgggcgtagt gtttctgcaa tttcttgaca acagctttct tagaaatagc
    20101 ctgtacactg ggctcattat gaagtttgga cttaacacat ttggcttttg aaatcgggaa
    20161 ccgagctcca agtggtaaat aattttccca atctaaagca aaaactccct gaaacagctc
    20221 ttcaaaagtc ttagctggga acgttcctac gatgattttg atacgatctg ctgcccgaag
    20281 ccaaaggttg gtttcgataa tagctctcac gtctccttga aaacgaacac gaccattttc
    20341 aacctgacaa tcgtagccca actctcgcac ttctcgtccc acaacagctt caagacctgc
    20401 tgccacagtt gcaattaaat taaattcttt tttcatgtta cagtcttgca agacctttct
    20461 atatgtccac tttaaaaaat gaggttgaga aaatttctca gccccaacct atatgcaatt
    20521 ttctataagc catgttttgt tccagaagtg actaggacca cttccttcga taatcatctg
    20581 tctaccacta gcagctctag ctgatagcag tcagaatact acgttcgttt ccgcgtactc
    20641 catgccccga ccaaaatttg ggttgctagc ttgaggggtt taccgcgttc cactctctct
    20701 gtttccagaa agactccgtc actgtggcac tttcaagcct actctggcct atccaaggac
    20761 ttagccattt caactgccgt aacgatttct cgtccctagg cttatggttt cgcctagcac
    20821 aaacactaca ggcatcacag cctgtgctag catggacttt cctcatgaga agcaattctc
    20881 ctcacgcgat tatccaaaaa ttgcatgtaa caagacctga attacaaatc agtattgtct
    20941 aaaatttgtt taccgaatac ttctttttca agacgattca agcgtttcaa aatatcaaaa
    21001 ttcgtcatag aagatgaagc agccacatca attggatctg ggtgactagg acttggagcc
    21061 gaactcactt gcggtttacg agttaattct tccttcaaat ccgcaatttc ctgacgaagt
    21121 gacttgacca aggcagcata ggtttcataa tccttgatga catcgtctaa aaactcatca
    21181 acttctacct tgctatagcc acggacttca cgtccaaact cttgttcaaa aatatctttt
    21241 gctgaaaaaa taatacttgc catgtctctc tccattctcg cttgctagta ttattatata
    21301 aaaaaaggca aacaaaaatc aaggtcaaag cttcaatttt cggaaaaatt ttcagcaagt
    21361 tcatttaatt gatcaaatgt taatctcttt ataaaatagt cctcttgatt tttcatcttt
    21421 tggtaaaaat aagctagttt cgtttcattt tcttcatcat aaaaaagata ggaactagtc
    21481 gtattttcca gcaaaaactg ctggtaatct cttaactgtc ccttgtgttc atagcgagga
    21541 taggcatatt tgacaaagtc tacctgctta aagcggctca gtttcatctg attgccttca
    21601 ttccaatttt ccccatgggt ttcaaatgca aaaatggtgg ccaactggaa accgtactcg
    21661 gttttcatat cctgagcaac ctctaaaacc caatattcaa aacccaaact tcctgtaaac
    21721 acaagccaag acaccccatc tgctgccata gcctctaaat ccctacgtat cgctttttta
    21781 atcaatttaa gacgaggatc cttgtcagaa aacaaaccca aatcaaaagc agaatagcct
    21841 aaaaccaaag ctgtagtcat ttttaaccct ttctgtgcaa atttatgata taatagagtg
    21901 atgttattgt accaataagg agaattatgg tcaactatcc acataaagtt tcatcacaaa
    21961 aaagacaacc atctctttct caacccaaaa atttcgcaaa tcgaggaatg tcttttgaaa
    22021 agatgatcaa tgctaccaac gactactatt tgtctcaggg cttggctgtt atacataaga
    22081 aaccaacccc tattcaaatc gtacgagtgg actatccaca acgaagtcgt gccaagattg
    22141 ttgaagccta ttttcgacaa gcttcaacga cggactattc tggcgtttat aatggatatt
    22201 acatcgactt tgaagccaag gaaacaaaac aaaaacgtgc gattccgatg aaaaattttc
    22261 atccacatca gattcagcat atggaacaag tccttgccca acaaggaatc tgctttgtcc
    22321 ttcttcactt ttcttctcag caagaaacct acttattgcc ggcattcgat ttgattcgct
    22381 tctatcatca agataaggga caaaaatcaa tgccacttgg atatattcga gaatatggat
    22441 atgaaatcaa ggctggtgcc ttccctcaaa ttccttatct caatgttatc aaagaacatt
    22501 tattaggtgg taaaacaaga tgaacaaacc aacgattctg cgcctaatca agtatctgag
    22561 cattagcttc ttaagcttgg ttatcgcagc cattgtctta ggcggaggag tttttttcta
    22621 ctacgttagc aaggctccta gcctatccga gagtaaacta gttgcaacaa cctctagtaa
    22681 aatctacgac aataaaaatc aactcattgc tgacttgggt tctgaacgcc gcgtcaatgc
    22741 ccaagctaat gatattccca cagatttggt taaggcaatc gtttctatcg aagaccatcg
    22801 cttcttcgac cacaggggga ttgataccat ccgtatcctg ggagctttct tgcgcaatct
    22861 gcaaagcaat tccctccaag gtggatcaac tctcacccaa cagttgatta agttgactta
    22921 cttttcaacc tcgacttccg accagactat ttctcgtaag gctcaggaag cttggttagc
    22981 gattcagtta gaacaaaaag caaccaagca agaaatcttg acctactata taaataaggt
    23041 ctacatgtct aatggcaact atggaatgca gacagcagct caaaactact atggtaaaga
    23101 cctcaataat ttaagtttac ctcagttagc cttgctggct ggaatgcctc aggcaccaaa
    23161 ccaatatgac ccctattcac atccagaagc agcccaagac cgccgaaact tggtcttatc
    23221 tgaaatgaaa aatcaaggtt acatctctgc tgaacagtat gagaaagcag tcaatacacc
    23281 aattactgat ggactacaaa gtctcaaatc agcaagtaat taccctgctt acatggataa
    23341 ttacctcaag gaagtcatca atcaagttga agaagaaaca ggctataacc ttctaactac
    23401 tgggatggat gtctacacaa atgtagacca agaagctcaa aaacatctgt gggatattta
    23461 caatacagac gaatacgtct cttaccctga cgatgatttg caagtcgcat ctacggtcgt
    23521 agatgtttcc aatggtaaag tcatcgccca acttggagct cgtcaccaag caagtaacgt
    23581 ttcatttggt accaaccaag ctgtggaaac caatcgtgac tggggttcat caatgaaacc
    23641 aatcaccgat tatgcacctg ccatagaata cggtgtatat gattccactg caactatggt
    23701 taatgatatt ccttataact atccgggaac aagcacacct gtctacaact gggatcgagc
    23761 atattttggt aatattactc tgcaatatgc ccttcaacaa tctcgtaacg tacctgccgt
    23821 tgaaacacta aacaaggttg gtttagatag agccaaaaac ttcctaaatg gtttaggaat
    23881 tgactatcca agcattcact actcaaatgc catttcaagt aacacaaccg agtcagacaa
    23941 aaaatatgga gcaagtagtg aaaagatggc tgctgcttac gctgcctttg caaatggtgg
    24001 aacttactat aaaccaatgt atatccataa agtcgtcttt agtgatggga gtgaaaaaga
    24061 gttctctaat gtcggaactc gtgccatgaa ggaaacgaca gcctatatga tgaccgacat
    24121 gatgaaaact gtcttgactt acggaactgg tcgtggtgcc tacctgcctt ggcttcctca
    24181 agctggtaag acaggtactt ctaactacac agatgatgaa attgaaaaac acatcaaaaa
    24241 cactggctat gtagctccag atgaaatgtt tgttggttat actcgtaagt attctatggc
    24301 tgtatggaca ggttattcga atcgtttaac tcctatcgtt ggagatggtt tcctagttgc
    24361 agctaaagtt tatcgctcaa tgataacgta tctatcagaa gatactcatc cagaagactg
    24421 gacgatgcca gacggcattt atcgaaatgg gcagtttgtt ttccaaaatg gagcaagacc
    24481 gacttggact gaaacaacat cccaatcatc ttcaactgaa agctcatcaa caagtgcaga
    24541 aagctctact agccaagcac cagcaacaag tcctgatgct agtactaatg gtcaaaacca
    24601 agcaccaaat gcacccggag ccaatcaaaa cccggctcca cagactcctc agccccctca
    24661 agttcaacaa caaccacaac agtaaacgaa aaaatcctga gaactctaaa ctcaggattt
    24721 tttcaatgcc aaaatgaaat acagaaatca agcgtagtaa aatgaaataa gacccgaaca
    24781 atttaatgtt ggtattcaaa taaatttata acaatatttt agaaattgta ttgtcctact
    24841 ccagattcag tttgttataa atttccccat aaaatagtga actgacataa aatctgaaca
    24901 aatcgattag gaaagttaaa tcaatttcta gtaatgtttt agaagctata gtctactatt
    24961 tctagcttca ttccacaata aaacgcatac tatcaagttt ttcatcacct gatagtatgc
    25021 gtttttcttt taaagacttt tg
//
LOCUS       DAVDHZ010000031        24961 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000031 DAVDHZ010000000
VERSION     DAVDHZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.032"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..441
                     /locus_tag="VUR46_001514"
     CDS             <1..441
                     /locus_tag="VUR46_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET5456916.1"
                     /translation="ETGFDTYFYREYGRSLKGQLRRGKVSGRRYQRISLVAGLTNGEL
                     IAPMTYEEMMTSDFFEAWFQKFLLPTLNTPSVIIMDNARFHRMGKLELLCEEFGHKLL
                     PLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            complement(647..2905)
                     /locus_tag="VUR46_001515"
     CDS             complement(647..2905)
                     /locus_tag="VUR46_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5456917.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGFQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILRGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPIGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADINKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3129..3359)
                     /locus_tag="VUR46_001516"
     CDS             complement(3129..3359)
                     /locus_tag="VUR46_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HET5456918.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVSYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3549..4232
                     /locus_tag="VUR46_001517"
     CDS             3549..4232
                     /locus_tag="VUR46_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5456919.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQVGILGVDLSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTIYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KRMGQGDKK"
     gene            4232..4966
                     /locus_tag="VUR46_001518"
     CDS             4232..4966
                     /locus_tag="VUR46_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5456920.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESKAVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5120..5977
                     /locus_tag="VUR46_001519"
     CDS             5120..5977
                     /locus_tag="VUR46_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET5456921.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTEKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGFRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALWTLDRK"
     gene            6119..6991
                     /locus_tag="VUR46_001520"
     CDS             6119..6991
                     /locus_tag="VUR46_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET5456922.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYSRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLPSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7273..7956
                     /gene="rpiA"
                     /locus_tag="VUR46_001521"
     CDS             7273..7956
                     /gene="rpiA"
                     /locus_tag="VUR46_001521"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET5456923.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7970..9181
                     /locus_tag="VUR46_001522"
     CDS             7970..9181
                     /locus_tag="VUR46_001522"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET5456924.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9183..9725
                     /locus_tag="VUR46_001523"
     CDS             9183..9725
                     /locus_tag="VUR46_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET5456925.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVENLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPLY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9741..10550
                     /locus_tag="VUR46_001524"
     CDS             9741..10550
                     /locus_tag="VUR46_001524"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET5456926.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHAGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            11047..12654
                     /locus_tag="VUR46_001525"
                     /pseudo
     CDS             11047..12654
                     /locus_tag="VUR46_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664829.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            12679..13191
                     /locus_tag="VUR46_001526"
     CDS             12679..13191
                     /locus_tag="VUR46_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET5456927.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13849..14559
                     /gene="deoD"
                     /locus_tag="VUR46_001527"
     CDS             13849..14559
                     /gene="deoD"
                     /locus_tag="VUR46_001527"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET5456928.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14582..15106)
                     /locus_tag="VUR46_001528"
     CDS             complement(14582..15106)
                     /locus_tag="VUR46_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET5456929.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(15159..15395)
                     /locus_tag="VUR46_001529"
     CDS             complement(15159..15395)
                     /locus_tag="VUR46_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET5456930.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(15463..16383)
                     /locus_tag="VUR46_001530"
     CDS             complement(15463..16383)
                     /locus_tag="VUR46_001530"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET5456931.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGSLNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWSSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16573..16976
                     /locus_tag="VUR46_001531"
                     /pseudo
     CDS             16573..16976
                     /locus_tag="VUR46_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17192..17773
                     /locus_tag="VUR46_001532"
     CDS             17192..17773
                     /locus_tag="VUR46_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5456932.1"
                     /translation="MYYAENPDTAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17770..19047
                     /locus_tag="VUR46_001533"
     CDS             17770..19047
                     /locus_tag="VUR46_001533"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET5456933.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTIAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            19065..19727
                     /gene="deoC"
                     /locus_tag="VUR46_001534"
     CDS             19065..19727
                     /gene="deoC"
                     /locus_tag="VUR46_001534"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET5456934.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19714..20103
                     /locus_tag="VUR46_001535"
     CDS             19714..20103
                     /locus_tag="VUR46_001535"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET5456935.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            20193..21245
                     /locus_tag="VUR46_001536"
     CDS             20193..21245
                     /locus_tag="VUR46_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET5456936.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDIANKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            21389..22924
                     /locus_tag="VUR46_001537"
     CDS             21389..22924
                     /locus_tag="VUR46_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456937.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVVENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEITGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RVASELVPAAALSGGNQQKAIIAREIDRVPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22917..23975
                     /locus_tag="VUR46_001538"
     CDS             22917..23975
                     /locus_tag="VUR46_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456938.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGLVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLSELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGASLAV
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23978..24934
                     /locus_tag="VUR46_001539"
     CDS             23978..24934
                     /locus_tag="VUR46_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456939.1"
                     /translation="MSITTLLTLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGCLFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYI
                     AIAFSFLAWFILFKTRFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPTVYLQIAPYVLTILVSAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7281 a         4515 c         5665 g         7500 t
ORIGIN      
        1 gaaacaggat tcgatactta tttttatcga gaatatggtc gctcattaaa aggtcagtta
       61 agaagaggca aagtatctgg aagaagatat cagaggattt ctttggttgc aggtctaaca
      121 aatggtgagt taatcgctcc aatgacttac gaagagatga tgacgagcga cttttttgaa
      181 gcttggtttc agaaatttct cttaccaaca ttaaacacac catcggttat tattatggat
      241 aatgcaagat tccatagaat ggggaagcta gaacttttat gcgaagagtt tgggcataaa
      301 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
      361 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttacga ggctcttttg
      421 tcctgctctt gtttcaattg actatagcag attgaaataa gatgagaaca aatcgattgg
      481 gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt tcgtactatt tcagattcag
      541 tctactatat atcataatgg acaaagggta agctgtcaag aaattacagt tattttagta
      601 aaaaagaagc agaaaaattt cattttctac tccttttcta taggatttat ttttcttttt
      661 cagaactttt aacttcagct tttttggcag atttaatctg aatgtttccc ttgctagtca
      721 taactgcttt gagatctttt tcgcttggat tttcaaggta gtagtcagtg attgtgtcct
      781 caatatagtc ttgaatagtc cgacgaagtg ggcgtgctcc catttttgga tcataaccta
      841 ggtcaaccaa cttttccttg accttgtcag ttacatccaa acgaatgttg ttgctagaga
      901 ggcgcttgtt aatatctgct agcatgagct cgacaatctg aaggaggtta tccttgctga
      961 gagccttaaa ttcgataatg ccatcaaaac ggttcataaa ctctgggcta aagaagttac
     1021 cgagttcacc gaggacagaa ttggtacgtc cttctctagc agcaccaaat ccaacgctag
     1081 cttcggtctt tcctgtacct gcatttgagg tcatgataat gatggcatcc ttgaagctaa
     1141 cggtgcgtcc ttgcccgtct gtcaaacgac catcgtccaa gacttgaaga aacatgtgca
     1201 taacatctgg gtgagctttt tccacttcat cgagaaggat gagagaatat ggattgtggc
     1261 gaactttttc agttaattga ccagcctcat catagccaac ataacctgga ggagcgccga
     1321 ccaacttagc cacactatgt ttttccatgt attcactcat atcaaagcga atcatactat
     1381 cagcagaacc aaaaagttcg atagccagtt gtttggaaag ttctgtctta ccgacaccag
     1441 ttggcccaac gaagaggaag cttccgattg ggcggttagg ggtaccaagt ccgacacgat
     1501 tacggcgaat agccttggca atcttatcga ctgcatcatc ttggccaata acatgagact
     1561 tgagatcttc ggctagatgg atgagttgag attgttcttt ctctttcaaa tcaccaatag
     1621 ggatattggt tttctgctcg ataatgtgct caatagtttt ctcgctgatg ataggagtat
     1681 cctggtctgt gatctttttc ttttgcattt ccttatactt ggcaatctgg tcgcggaagt
     1741 aggccgcctt ctcaaaatct tcttctcgtg tagcttgaga cttgagattt tcagcctcaa
     1801 tcaagcgctg atcaattact ttaggatcca caaaattcaa ggtcaagttc atcttagaac
     1861 cagcttcatc taggaggtca atggccttgt caggcaagaa gcgatcttgg atgtagcgat
     1921 tggaaagagt tgcagctgct tcaatcgcag catcggtata ttgaacgtgg tggtaatctt
     1981 cgtatttctt ttgaatccct ctgagaatag tgattgtttc gtccaccgtt ggttcatcga
     2041 ctttaacagg ctgcatacga cgctcgaggg cagcatcctt ttcaatgata cggtattcat
     2101 tgagggtagt agcaccgact agttgcagtt ctccacgagc aagggctggc ttgaggatat
     2161 ttcctgcgtc catattacca tcactcgcag aaccagcacc aacaatttca tggatttcat
     2221 cgataaagag gatgatgtct tcacgtttgc gaatttcttc catgagtttt tgcatgcgtt
     2281 cttcaaattg tcctcgaatc cccgttcctt gaactaagct aaccacatcc agacggatga
     2341 cttgtttacc ttggagttta tgtggcacat cgccatcgac aattttctga gctagacctt
     2401 cgacaacggc cgtttttccg acaccaggtt caccgataag gacaggatta ttcttggttc
     2461 tacgattgag aatctcgatg acacggataa tctcatcgtc gcgcccaata acggggtcaa
     2521 tgtctccacg acgggcaatt tcagttacat taataccaaa ttcttccagc aggccttttt
     2581 cttggctagg tggcggagtt tgagcagatc cacgattttg gaaaccataa ccgccgtttc
     2641 caccgtaacc tccacctgat tgggttgggg gaataggagg agtattgcta gaaggtctga
     2701 aattgtttag atcattgaag aaatcaccaa agggatcgaa gtcacgattg ttcagatccg
     2761 tcataccttt gaagaggcta ttgttaggat ctgttttgat aatcttatag cagttttgac
     2821 agaggtcaat ttgtttttgt tttccattga gattggtgta aagatgaatt gttgagtcgt
     2881 taattttaca gttttgacaa agcatacatc tacctcattt ctttctttag cctgacttgt
     2941 ttaaaggtca aaaatagtca aattctatac tctcattata acaggattgg ggtgtaaagc
     3001 aagtaaaaag attgaagctt tgagaagttg ttacaatgaa aatttttgtg aatttggact
     3061 ataaaaaaat cctatttgtg agacaaaaag gattttactt agacatgcag ggacaatccc
     3121 agcttgtttt agtagagaag ttcgtaaatt tccattgcga ttaagtcaat gctatcaaac
     3181 gtatacgttt cgcgatcttc tacgtcacga agggtaaaga ttgggccgtt ttcttcgtcg
     3241 tggctgtacg aaacttctgc aacaacaact ccttcgcgtt caaaattacg ttttaaattt
     3301 ccgccatcgt ttgccattgc ttcaaggcgg ttgatgattc taaccaaatg tgattccatt
     3361 ttgattctcc ttcatttctt atcgttacta ttttaccata aaggaggcca atttgactag
     3421 aaaaaactaa gatttcttgc taattctgct agtttaaaga tttttaaata aattggataa
     3481 aagatttgaa ttttaattca aaacatgtta taatcataca gtattctatt ttagaaagca
     3541 gtgtgactat gaatttttct tttttaccta agtatttacc ttattttaac tatggggctg
     3601 ttgtgacgat tcttatttct atctgtgtta tctttttggg aactattttg ggtgttgtct
     3661 tggcttttgg gcaacgttca aagtttaaac cgcttgtttg gttggccaac ttgtacgttt
     3721 ggattttccg tgggacaccg atgatggttc aaattatgat tgcctttgct cttatgcata
     3781 tcaatgctcc gactattcag gttggaattt taggtgttga tctttctcgt ctgattccag
     3841 ggattttgat tatctctatg aacagtggtg cttatgtttc tgagactgtt cgtgccggaa
     3901 tcaatgcagt tcctaagggg cagttagagg cggcttattc tttagggatt cgtcctaaaa
     3961 atgctatgcg ctatgtaatt ttaccacaag ctatcaaaaa tatcttgcca gctttgggga
     4021 acgaatttat caccattatc aaggacagct ccctcttatc agctatcggt gttatggagt
     4081 tgtggaacgg ggctacaaca gtttctacaa caatctatct acctttaaca ccacttttat
     4141 ttgcagcttt ttattacttg attatgactt ctattttgac agtagccttg aaagcttttg
     4201 aaaaacgtat gggacaagga gataagaaat aatgacagaa accttgataa aaattgaaaa
     4261 tttacataaa tcatttggaa agaatgaagt attgaagggc atcaacctcg agattaaaag
     4321 aggagaagtt gtcgttatca tcggtccttc agggagcggg aaatctacct tgcttcgctc
     4381 tatgaatttg ttggaagaag cgaccaaggg taaggttatc tttgagggag tcgatattac
     4441 ggacaagaag aatgacctct ttgccatgcg tgagaagatg ggcatggttt tccaacaatt
     4501 taacctcttt cctaatatga ctgtgatgga aaatatcacc ttgtcaccta tcaagaccaa
     4561 aggtgagagc aaggctgttg ctgagaagag agcccaagag cttttggaaa aagttggttt
     4621 gccagataag gcagatgctt atccacagag tttgtcaggt ggccagcaac aacggattgc
     4681 cattgcgcgt gggttggcca tggaacctga tgttttgctc tttgacgagc caacttcagc
     4741 actagatcct gagatggttg gagaagttct ggctgttatg caagatctag ccaagtcagg
     4801 aatgaccatg gttatcgtaa cacatgagat gggatttgcc cgtgaggtgg cagatcgtgt
     4861 catctttatg gcagacggtg tggttgttga agacggaaca ccagaacaga tttttgaaca
     4921 aacccaagaa caacggacta aagacttctt gagtaaggtt ttataatcta ttttaaaatt
     4981 tcaagacaag attagtgaaa agctcaacca gagctttttc ttatagtttg aaactatagg
     5041 attgcctagg aaagaagtgt tagagggtgc tggcagtttt tggtataatg gaagatattt
     5101 gaaagaaaag agaagtgata tgacacagat tattgatgga aaagctttag cggccaaatt
     5161 gcaggggcag ttggctgaaa agactgaaaa attaaaggaa gaaacaggtc tagtgcctgg
     5221 tttggtagtg attttggttg gggacaatcc agccagccaa gtctacgttc gcaacaagga
     5281 gaggtcagct cttgcagctg gtttccgtag cgaagtagtg cgagttccag agaccattac
     5341 gcaagaggaa ttgttagacc tgattgctaa atataatcag gatcctgctt ggcatgggat
     5401 tttggtccag ttgccattac caaaacacat tgatgaagaa gcggttctat tggctattga
     5461 cccagaaaag gatgtggatg gtttccatcc cctaaacatg gggcgtctct ggtctggtca
     5521 tccagtcatg attccatcaa cacctgcagg aattatggaa atgtttcatg aatatgggat
     5581 tgacttggaa ggtaaaaatg cggtcgtcat cggccgctcc aatatcgttg gaaagcccat
     5641 ggcccagctt cttttggcca aaaatgcgac agtaaccttg actcactcac ggactcataa
     5701 tcttgccaag gtggctgcta aggcagatat tcttgtggtt gcaattggtc gtgctaagtt
     5761 tgtgactgct gactttgtga aaccaggtgc ggtagtcatt gacgttggaa tgaaccgcga
     5821 tgaaaatggt aagctctgtg gggatgtgga ttatgaggcg gttgccccac ttgctagcca
     5881 tattacgcca gttcctggag gtgtaggtcc tatgaccatt actatgctga tggagcaaac
     5941 ttatcaggcg gcactttgga cattggatag aaaataagag aaacattcga ttaatagagt
     6001 gtattttcta tagctatatc taaaatggca gaaatgaata ttaaatttta gatataagat
     6061 tacaaaagga ggtctgcgcc tcctttttgt tgtataataa aagtgagagg aaaaaaggat
     6121 gaaagtgatt aatcaaacct tactagaaaa agttattatt gaacgttctc gttcaagtca
     6181 taaaggagat tatagtcgtc tgctgctgct tggtggtact tatccttatg gaggtgccat
     6241 catcatggct gctttagcag ctgtaaaaag cggtgcagga ttggtgaccg ttggaacgga
     6301 cagggaaaat atcccggctc tgcacagcca tttacctgag cctatggcct tttctcttca
     6361 agaccagcaa ttgttaaaag agcaattgga gaaggcagaa gttgtcttgc tggggcctgg
     6421 tttacgagac gatgcttctg gagaaaatct agtaaaacag gtctttgtta atttaagcca
     6481 aaatcagatt ttgattgtag acggaggtgc cttgaccatt cttgctagga caagtttgtc
     6541 atttccctca agccagctta tcctaactcc tcaccaaaaa gaatgggaaa aattatctgg
     6601 aattacgatt gaaaagcaaa aggaagatgc aacggctagt gttctgcctt ctttccctca
     6661 aggaacaatt ttggtggaga aaggcccagc tactcgtatt tgggaagttg gccaatctga
     6721 ttattaccag ttacaggttg gtggtcctta tcaggcgact gggggaatgg gagatactct
     6781 ggctgggatg atcgcaggat ttgtaggcca attccgacag gccagtctct acgagcgtgt
     6841 ggcagtagcg acccatcttc attcagccat agctcaagaa ctatctcaag aaaattatgt
     6901 ggtcttaccg acggaaatca gcaggtatct tcccaaaata atgaaaatta tttgtcaaca
     6961 agagagggta agcaaagata aacttgttta aaatagacag ataaatctac ttccttctct
     7021 taatttatga ttcttgaaat gcacctgctt taaggctaaa ctagacgtat caaagttaag
     7081 agtttgtttt tgtaactgga aagagatgaa caaatcaaat acataaaaga taaactcatt
     7141 tttattcgtt tggtaaaaat aaaatacata tttttaaaga aagattgatg aaaaatgtag
     7201 atttgatgtt tttacttgaa taaaaagcgg tttcatagta aaataagaac tgagaatgat
     7261 ggaggtaaat cggtggaaaa tctgaagaaa atggcaggta tcaaggctgc tgagttcgtg
     7321 agcgatggaa tggtcgttgg acttggaaca ggctcgactg cctattattt tgtcgaagaa
     7381 atcggtcgtc gtatcaagga agaaggattg cagattacag ctgtaacaac ttctagtgtg
     7441 accactaaac aggcagaagg ccttaatatc ccgctcaagt ctattgacca agtagacttt
     7501 gtcgatgtga cggttgatgg cgcggatgaa gtggatagtc agtttaatgg aattaaaggc
     7561 ggtggtggtg cccttctcat ggaaaaggtg gtcgcaacac catcaaaaga atacatttgg
     7621 gtggtggatg aaagcaagct ggtcgaaaaa ctaggtgctt ttaaattgcc agtagaagtg
     7681 gttcagtatg gtgcagagca ggtctttcgt cattttgaac gagctggcta caaaccaagt
     7741 ttccgtgaaa aagacggcca acgttttgtg acggatatgc agaattttat cattgacctc
     7801 gccttggatg tcattgaaaa tccaattgct tttggacaag aattggacca tgtcgttggt
     7861 gttgtggagc atggtttatt caatcaaatg gtggataagg taatcgttgc tggacgagat
     7921 ggagttcaga tttcaacttc aaaaaaagga aaatagaagg gggcataaga tgtctaaatt
     7981 taatcgtatt catttggtgg tactggattc tgtaggaatc ggtgcagcac cagatgctaa
     8041 taactttgtc aatgcagggg ttccagatgg agcttctgac acactgggac acatttcaaa
     8101 aacagttggt ttgaatgtcc caaacatggc taaaataggt cttggaaata ttcctcgtga
     8161 aactcctctt aagactgtag cagctgaaag caatccaact ggatatgcaa caaaattaga
     8221 ggaagtatct cttggtaagg atactatgac tggacactgg gaaatcatgg gactcaacat
     8281 tactgagcct ttcgatactt tctggaacgg attcccagaa gaaatcctga caaaaatcga
     8341 agaattctca ggacgcaagg ttattcgtga agccaacaaa ccttattcag gaacggctgt
     8401 tatcgatgat tttggaccac gtcagatgga aactggagag ttgattatct atacttcagc
     8461 tgaccctgtt ttgcagattg ctgcccacga agacattatt cctttggatg aattgtaccg
     8521 tatctgtgaa tacgctcgtt cgattaccct tgagcgtcct gcccttcttg gtcgcatcat
     8581 tgctcgccct tatgtaggtg aaccaggtaa cttcactcgt acggcaaacc gtcgtgactt
     8641 ggctgtatct ccattttccc caactgtttt ggataaattg aatgaggctg gtatcgatac
     8701 ttatgctgtg ggtaaaatca acgatatctt taacggtgct ggtatcaacc atgacatggg
     8761 tcacaacaag tcaaatagtc atggaattga tacactattg aagactatgg gacttgctga
     8821 gtttgaaaaa ggattctcat tcacaaacct agttgacttt gatgcccttt acggccatcg
     8881 tcgtaatgct cacggttacc gtgattgctt gcatgagttt gatgaacgct tacctgaaat
     8941 tatcgcagct atgagagaga atgaccttct cttgattact gcggaccatg gaaatgaccc
     9001 aacgtatgca ggaacggatc acactcggga atatattcca ttgttggcct atagccctgc
     9061 ctttaaagga aatggtctca ttccagtagg acattttgca gatatttcag cgactgttgc
     9121 cgataacttt ggtgtggaaa ctgctatgat tggggaaagt ttcttagata aattggtata
     9181 agatgacgcg ctatgctttg ctggtgagag gtatcaatgt tggtggtaag aataaggtcg
     9241 tcatggcgga gcttcgtcaa gaattgacaa acttaggact ggaaaaggtt gagagctaca
     9301 tcaacagtgg caatattttc tttacttcga tagattccaa agcccaattg gttgaaaagc
     9361 tagagacttt ctttgcagtc cattatccat ttattcagag cttttcttta ctgagtctag
     9421 aggactttga ggcggaactt gaaaatctac cagcttggtg gagcagagac ttggcacgaa
     9481 aagattttct cttttacact gagggtttgg atgtggacca agtcatcgcg acagttgaaa
     9541 atttagagct gaaagatgaa gtgctttatt ttggaaaact tgggattttc tgggggaaat
     9601 tttctgaaga atcctattct aagactgcct atcataagta cttgctgaag gtgcctttat
     9661 accgccacat tactattcgt aatgctaaaa cctttgacaa aattggtcaa atgctaaaaa
     9721 aataataaag gagacacaca atgacatttt taaacaaaat ccatgaaact gctactttcc
     9781 tgaaagaaaa gggaattgca gcccctgagt tcggtctaat ccttgggtca ggacttggag
     9841 aattggcaga agaaatcgaa aatccagttg tagtagacta tgctgagatt ccaaactggg
     9901 gccgttcaac agtagtcggt catgctggta aattggtata tggtgaactg gcaggtcgca
     9961 aggtcttggc tcttcaaggt cgtttccatt tctatgaagg gaatcctctg gaagtggtga
    10021 ctttcccagt tcgtgtgatg aaagttcttg gatgtgaagg tgttattgta accaatgcag
    10081 ctggcggtat cggatttggt cctggtacct tgatggctat ctcagaccat atcaacatga
    10141 cggggcaaaa tccattgatg ggtgaaaact tggatgactt tggcccacgt ttcccagata
    10201 tgtctagggc ctacacacca gaataccgtg ccactgccca tgaagtggct aaaaaactta
    10261 atatcaagct tgatgaaggt gtctatatcg gagttactgg tccgacttat gaaacaccag
    10321 cagaaattcg ttcctataag acactgggag cagatgcagt tggtatgtct acggttcctg
    10381 aagttatcgt ggcagcccac gctggcttga aagttctggg aatttcatgt atcactaact
    10441 ttgcggctgg tttccaagaa gaactcaatc acgaagaagt tgtagaagtg actgaacgtg
    10501 ttaaaggtga tttcaaaggc ttgcttaaag cgattcttgc tgaattgtaa gaaaaaagat
    10561 ttaaaagggg gagtgcctct gttttttcag gattgactgc ctatccggat taaagaagaa
    10621 acagaggaat actatgagct tcttcctgct cttataactg aaagaagcgg aagaataggt
    10681 atgtctgatc tgatagccag cattgtgaaa gacaagattc taggatacta gcattagctt
    10741 cctagccaag cagactagta tgataaggag agatgagaat gaattgactt tctgaatttc
    10801 tcagtcttat catatatagc acaatgagat ttcgcttgag tctgcttgta aataaacgaa
    10861 aagaaagata agaaataatg aaaattggtc aacgaattat gcgctttggc ataaaaaatt
    10921 aagtatcgga gttgtatctg ttgtagtcgg ctttgatttc tagctccagc tggaatttca
    10981 gccaatgaag taaagttaga tgtaacatct gaagtggtaa taggtgtgct agattctaag
    11041 gaggaattga aagagtcaga aaatgatgct ccaaaactag aaactcctct tagagaggag
    11101 ccaagactag ctcctcaaac gcttccggaa gcaagtgaag ttcttgaaaa caaaagggaa
    11161 gagtcaaaag tagagataac agagccagct caagactcac ctattcttgc tcctgtagaa
    11221 gaaactaaag aagaagctgt gacagaaaaa ccaacaaata ctcgttctct aactgcagaa
    11281 gatttggtga agatttccaa aggggaattg catttagaaa atgatttgat tgatgaatct
    11341 ttctatggtg aaaaagctct tgatttggaa ggggatgatg accaggatgg catcaaaaac
    11401 aaagatggta aggattatct aggatataac agtcatccct tgctagcaga cagtgatggg
    11461 gatggtttgg cagatgggga agatgataat aagaaagaat ggtatgtcac agaccgtgat
    11521 tctcttctct ttatggagtt agcttatcga gacgatgatt atattgagaa aattttagat
    11581 cataagaatc ttttccctag tctctatctt gaccgtcaag aacacaaact catgcacaat
    11641 gaattggctc ctttctagaa gatgaaaaaa gcctactata cagatagtgg cttggatgct
    11701 ttcttatttg agaccaagag cgaccttcct tatctcaaag atggaacggt gcacatgttg
    11761 gctattcgtg gaacgcgagt taatgacgcc aaggacttga gtgcagattt ggttttatta
    11821 ggtggaaata aactagctca agcggatgat atccgcaagg ttgttgggga attagccaag
    11881 gatataagta ttactaagtt gtatatgaca ggtcattctc ttggatgcta cctagctcag
    11941 attgcagagg ttgaagctta ccaaaaatat cctgattttt ataaccatgt attgaggaaa
    12001 gtgacaactt tcagtgctcc taaagtgatt acttccagaa ctatttggaa tgctaagaat
    12061 ggtttctggg atgttggttt ggaaagtcgt aaattagctg ttagtggaaa aattaagcat
    12121 tatgtggttg ataatgacaa tgttgtgact cccttgattc ataataatcg tgatattgtt
    12181 acatttacag gtaattcacg ctttaaacac cgttctcgtg gctattttga aagtccaatg
    12241 aatgatattc ctaactttaa tattggtaaa caagctacct tggataaaca tggttatcgt
    12301 gatccgaaat tggataaagt gcgattcttt aagaaacagg ctctgcctcg atcttctagt
    12361 caaccaagcg ctgaaccaat ggaaaatatt gccttaggaa aacaggttac tcaaagttcg
    12421 acagctttcg gaggagatgc tagaagagct gtggatggca aagtcgatgg taactatggt
    12481 cacaattctg tcactcatac aaacttccaa tctaagcctt ggtggcaagt agatttggct
    12541 aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa cagacactgc ccaggataga
    12601 ttggcaaact ttgatgtcat tcttttagac agttctggta aagaaattga gtgaaaacgt
    12661 ataatatctc ctaaagatgt gtcagcacaa attacgatta accataaaaa agcgcgctat
    12721 gttcggattg agctagaagg ctataatgcc ctcagtcttg cagaagttga agttttccgc
    12781 tttatagcta cgaatgctga aacggcgaca caagtttcta agccagttca accaatcagt
    12841 cagactcctg tgaaagataa aacattgaca attcaacaca gtggagctta cattgcccgc
    12901 tactccataa cttgggaaga agttccagta gataaagatg gaaaccaagt tgttcgtagt
    12961 cattcttggg aaggaaacgg tcgcaaccag actgcaggtt ttgtcctcaa cctcccaatc
    13021 aaagaaaata tgagaaatct gcgagttaag attgagaaaa agacgggcct actatggaat
    13081 agatggcaaa caatctatga aaacagacca attttagctc aaccccaccg taaaattacc
    13141 cattggggta cgacattgaa ttccaaggtg agtgacgatg atgtcttgta atctgatggt
    13201 agaatgacag ttagtttgtc tagtttataa gaaagtacta cctgagcttg aatagaactc
    13261 aggtagctct ctatgaaaga acaaaattaa tactcaatga aaatcaaaga gcaaactagg
    13321 aaactagccg caggttgctc aaagcactgc tttgaggttg tagataagac tgacgaagtc
    13381 agtcacatat ataatccaag gcgacgttga cgtggtttga agagattttc gaagagtata
    13441 aacagaaagg tagagtgcgt gttctaattt gaacacgagt agaaaacttt tctaaaaaca
    13501 aaaacgaaag gatgggtaaa ctgtattcgc taaactgaat acgggcgact ctcctctaaa
    13561 tcaaaattaa gaaagaaagg aattgacccc accctaaaag cagtgggaaa aagatagttg
    13621 gtctagcgag catcgctcac tgcgcccaac tcctattttc ccttcgcttt ttgacgggtt
    13681 tggtatcttt ctcaatataa aatataaaat aaagaaaggt agagcgtgtg ttttgatttg
    13741 aacacgagcg gaaaactcgg aaaatagata atctgactga aaaatcagga tttctcgtca
    13801 ggttcctaat tttcagtcgt tttcttctcg ctctttgtat cataaattat gtctatccat
    13861 attgctgctc agcagggtga aattgctgat aaaattcttc ttcctgggga tcctcttcgt
    13921 gctaagttta ttgcggagaa tttccttggt gatgctgttt gttttaacga agtgcgtaac
    13981 atgtttggtt acactggtac ttacaagggt caccgtgtat ctgtcatggg aactgggatg
    14041 ggaatgccat ctatttcgat ttatgcgcgt gagttaatcg tagactacgg tgtgaagaaa
    14101 ttgattcgtg tgggaactgc aggttctttg aatgaagagg ttcatgttcg tgaattagtt
    14161 ttggcgcagg cggctgcaac caactcaaac atcgttcgta atgactggcc acagtacgat
    14221 tttccacaaa ttgctagctt tgatttgctt gataaagcct accatatcgc caaaaaactt
    14281 ggtatgacta ctcacgttgg gaacgttttg tcatctgatg tcttttactc aaattacttt
    14341 gaaaagaata tcgagcttgg taaatgggga gtcaaggctg tggaaatgga agcagcagct
    14401 ctttactatc ttgctgccca ataccatgtt gatgcgctag ctatcatgac catctctgat
    14461 agcttggtca atccagacga agacacaact gcagaagaac gtcaaaatac cttcactgat
    14521 atgatgaagg ttggtttgga aaccttgatt gcagaataat tatagccaaa aaggaagccc
    14581 tttatgaatt gtaggacttc cttttcttat ccagaaattg atctagctct ctctgatttc
    14641 gaagaatagt gactttatgt gaatattctt ggcaaagttt ttggtaattt tctttttgag
    14701 ttttgctacg cccatcccaa agaatccatc tgataaactc ccactcaaag cgttcagggc
    14761 aatctgccgc catactttct ctgacttttc cacggtattt aagataacgc ttaaaggctc
    14821 taaagagaca ggtcaatggc gaaaaattga gaaagatgat ttggtcagct tcttgcattc
    14881 gttcttggta gtagcaccaa gaataattac catcgatgac ccaagcttta tgcttggtga
    14941 gaaagttttt tatctcggtt aacatccatt cgcagtcact gtcttgccaa ccaggttgaa
    15001 attggagtgt gtccatgtgc agttttggaa tggagtagta gttagataac ttttctgcta
    15061 gagttgactt accagaacca gaatatccga taattgcgat tttcattttc taccttttcc
    15121 tatttggaga caaaaaaaca gcctctatgg actgtttctt atttagcaag tttagctgaa
    15181 agacgagctt tatcgcggct tgctttgttt ttgtgaatca aacctttagt ttctgcttta
    15241 tctatagctg agctagcagc acggaaaagt tcttcagatg ggtttgcttc gaaagctttt
    15301 atagcagtac gcatagctga tttttgagct gagttctttt cgttttgttt aacgttcaat
    15361 tcagcgcgtt tgatagctga tttaatgttt gccaatgttc ttacctccat atttactaac
    15421 tataccatta tatatgaaaa cttacgtttt gacaagggaa aattactttt ttaagtaaat
    15481 ttcatcgatt tcatggttct tgcttttatg aagaatcact tctgcacgat ttctggttgg
    15541 ttcaatataa ttttgcagat ttgtgaggtt gatactgctc cagacctgat gggcaaagga
    15601 ctccacttcc ccaatcggca tctgagtaaa acgataatag tagctatcag ggtcgttttg
    15661 ggctaggctc agcattttca agaaacggtc cagataccaa ctttcaatat catccactcc
    15721 agcatctaca tagatggaaa agtcaaagaa gtcagtgata tagagacgat cgttttgtgg
    15781 attttgaaag acattaattc cctcaacaat tacaaaatca gcagctttga cactttgttt
    15841 cttttcgggt acgatgtcgt aaacttcatg agaatagaca ggaatatcta catcttgtcc
    15901 atttttgatg cggtccaaga agttgagaag agcttccata tcatagcttt caggaaatcc
    15961 tttacgattt aaactcccct gctcaatcaa ggtttgattg ggatagagaa aaccatcagt
    16021 tgtaaccaac tcaaccgtag catctgtaaa cgtacgggac agtaggattt gaagtaggcg
    16081 actggttgtg gattttccaa cggcaacact cccagaaacc ccaataataa aaggttgaga
    16141 tttactttca cgttggagga aaattccttt tgaaaaggct aaatcttcct tagttcgctt
    16201 gtaaatctga atcagatgag ccaaggggag atagatatct gtaacgtctt ggagactgat
    16261 ttggtcatta aaactcttga tagattccaa ttcttcttct gtcaaaggag gtgttgtctt
    16321 gcgatgtaaa gattgccaag tctggcggct gattttttca aaatgtaaaa attcgttggt
    16381 catttgtttt cccctagata ttttgtctat cataccataa aaagctaaaa aaataaagcg
    16441 gtttcttgaa tgtggtaagt caatgatata tagtataagt gatcaattta ttgatgaaat
    16501 aggagataga ttctactgat ttataagctt ataaaggagg ctttttagtt cacaacttat
    16561 aggaggtgta ctatgaaaat cttaaaacgt tacatattgg aactctgttt tattttaagt
    16621 tttgctttac cttttataaa aggaaccaat gcagataatg gtagatgctt tgtggaaacc
    16681 tattacggtt ttactttttt gatggaacat gctattgtaa cagctgtctt tatctgttcg
    16741 ttcttaattg ctttcttact aaaaaacgat gggcgaaatg gattgctgct ggtagttatt
    16801 gctttttagt cctatggatt gcgacagagg gttatttctt ccatatgtca ccagaagatt
    16861 tgatacgact ttggacaagt ttggaaatcc tgacacaaac gtatcagttg ggcttttatc
    16921 taaacatttt gttaggaatt ttgttgatga ttaagcattt gaaggttaag caatagaaat
    16981 aataatctgc ctgattatag atgataaact ttttgttttt atctggactg tgatatttat
    17041 agttctaaat ggtttattat ttataagtgt tgaaagagat tgaagaaaat ggcttcgtga
    17101 ctcgctttct tcggtctttt tcgttttatt atcaatttgt aaacgattta caatttgagt
    17161 caaattatgg taaaatagtg tcatgagtaa aatgtattat gcagaaaatc ctgacactgc
    17221 tcacgacatt catgagttga gagtagagtt gttgggacaa aaaatgacct ttttaacgga
    17281 tgcgggtgtt tttagcaaga aaatagttga ctttggaagt caactattgc tcaagtgtct
    17341 tgaggtcaac caaggagaaa ctgtccttga tgtaggctgt ggttacggac ctttgggttt
    17401 gtccttagct aaggcttatg gagttcaggc tactatggtt gatatcaaca ctcgtgcctt
    17461 ggatttagct cggagaaatg ctgaaaaaaa taatgcaaaa gcgacgattt tccagtccaa
    17521 catctatgaa caagttgaag gacattttga tcatgtcatt tccaatcctc ctatccgtgc
    17581 gggcaagcaa gtcgttcatg aaatcattga gaaaagtaaa gatttcttgg aaactggtgg
    17641 ggatttgaca atcgtcatcc agaaaaaaca aggggctcca agtgctaagt ccaagatgga
    17701 ggatgtgttt ggtaattgtg aaatccttaa aaaagacaaa ggatactata tccttagaag
    17761 tgtgaaagaa tgagagcagt tgatttaatc caaaaaaaac gagacggtca agaactgact
    17821 tcaagtgaaa ttgaatggct ggtagaaggc tatgtgtcag gaactgttcc tgattatcag
    17881 atgtctgctt ttgctatggc tgtttatttt aaaggaatga cgactcgtga aatttctgat
    17941 ttaacgatga atatggttaa gactgggcaa gagtttgacc tgtcagccat tgatggtgtg
    18001 aaagttgaca agcattctac tggtggtgtc ggcgataagg taaccttgat tttagctcct
    18061 cttgttgcta gcttcggtgt gcctgtagca aaaatgagtg gtcgtggtct tggccataca
    18121 ggcggaacaa ttgataaatt ggagtccatt aggggctatc aagtagaacg tagtcaagag
    18181 gattttattc gtcaggttca ggatattgga gtatctgtca ttgggcaatc agaccagctg
    18241 gtcaaagcag ataagcttct ctatgccctt cgtgatgtga ccgcaactgt cgacacgatt
    18301 cctttgattg cgagttcggt gatgagcaag aaaattgcgg caggggcgga tgctattttg
    18361 ctagacgtga ctgtcggtga gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg
    18421 gctcaaacta tggtagatct tggtaaggtt gttggacgga agacaatagc agtgattacg
    18481 gatatgagcc agcctttggg acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg
    18541 gagattttgc aaggtcaagg acgtcaggat attacccact ttatttgtga attggctcaa
    18601 attatgcttg gtttggcaaa tgttaacaag actgttgaag aagttcacca acatcttgag
    18661 aatggtcaag cactggctaa gtttgaggaa atggtgcaag cccaaggtgg agacttggaa
    18721 gacctctatc gtcctgtaaa tgtagctcat gtggtggaaa tccctgctca ggaaacgggt
    18781 gtcatttcag ctcttccagc tatggacttt ggtctttatg ccatgaggct gggtgctggt
    18841 cgtgcagtta agtctgatgc cttggactat gaaacaggaa ttgtttttga aaagaagatt
    18901 ggagactccg ttcaaaaggg tgaaattgtt gcaaaagtat acacaaatga aaaaattcca
    18961 cctcaactag ttacagattt ccaaaaatgt gttaaaataa gtgatgaagt gaaaaaaatc
    19021 cgtgaaattg tagaaatcat ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat
    19081 atatagatca tacgctttta aaacaagatg caaagaaaaa acaaattgat agtttgttgt
    19141 ctgaggctag agagtatgac tttgccagtg tttgcgttaa tccgacctgg gttgaacatg
    19201 ctaaaaaagg acttgaaggc acagatgtta aggtttgcac agtagtaggt ttccctttgg
    19261 gagcaacaac ttcagccgtg aaagcatttg agacaaaaga agctatccaa aatggtgcag
    19321 atgagattga tatggtgatc aatgttggag ctctcaaatc aggtaattta gccttggttg
    19381 agtcagatat tcgcgcagta gtggaagcaa gtggtgataa gttagtgaaa gtcattattg
    19441 aagcttgcct tctgacagac caagaaaaag ttgttgtttg ccaattggcc caaaaagctg
    19501 gggctgactt tgtcaaaaca tctactggct tttcaactgg tggtgctacg atagcagatg
    19561 ttacattaat gcgtgaaaca gttggatctg atatgggtgt caaggccgcc ggtggagctc
    19621 gttcttatgc agatgctctt gcctttgtcg aagcaggtgc gacccgtatc ggaacgtcag
    19681 ctggggtagc tattttaaaa ggagaattgg cagatggcga ctactgagtt gattgaactg
    19741 gcaattgaaa ccagcaaaca tgcctatgtc ccctattctc actttcctat cggagcagtt
    19801 ttagtagcta aagacggaag tgtttacacg ggagtgaata tcgaaaatgc tagctatcct
    19861 ttgaccaatt gcggtgagag aacagcagtt tttaaggcta tatctgaagg ccaaagagaa
    19921 ttttcagaat tgattgtcta tggtcaaact gaaaaaccga tctcgccatg tggtgcttgt
    19981 cgccaagtaa tggtcgaatt ttttgaacaa gatttaaaag tgaccttagt cgcaaaagat
    20041 aaatcgacgg tcgagatgac ggtcggggag ttacttccat actcttttac agacttaaac
    20101 tagtctgagt cgctctttga gtggcacggt ccttgtggcc aaccaatcca tacttgcaac
    20161 atcgttgcac atcttattta ggaggttcag taatgaacaa gaaacaatgg ctaggccttg
    20221 gtctagttgc agtggcagca gttggacttg ctgcatgtgg taaccgctct tctcgtaacg
    20281 cagcttcatc ttctgatgtg aagacaaaag cagcaatcgt cactgatact ggtggtgttg
    20341 atgacaaatc attcaaccaa tcagcttggg aaggtttgca agactggggt aaagaacaca
    20401 atctttcaaa agataatggt ttcacttact tccaatcaac aagtgaagct gactacgcta
    20461 acaacttgca acaagcggct ggaagttaca acctaatctt tggtgttggt tttgcccttc
    20521 acaatgcagt tgaagaagca gctaaagaac acactgactt gaactatgtc ttgattgatg
    20581 atgtgattaa agaccaaaag aatgttgcga gcgtaacttt cgctgataat gagtcaggtt
    20641 accttgcagg tgtggctgca gcaaaaacaa ctaagacaaa acaagttggt tttgtaggtg
    20701 gtatcgaatc tgaagttatc tctcgttttg aagcaggatt caaggctggt gttgcgtcag
    20761 tagacccatc tatcaaagtc caagttgact acgctggttc atttggtgat gcggctaaag
    20821 gtaaaacaat tgcagccgca caatacgcag ccggtgcaga tattgtttac caagtagctg
    20881 gtggtacagg tgcaggtgtc tttgcagagg caaaatctct caacgagagc cgtcctgaaa
    20941 atgaaaaagt ttgggttatc ggtgttgacc gtgaccaaga agcagaaggt aaatacactt
    21001 ctaaagatgg caaagaatca aactttgttc ttgtatctac tttgaaacaa gttggtacaa
    21061 ctgtaaaaga tattgctaac aaggcagaaa aaggagaatt ccctggcggt caagtgatcg
    21121 tttactcatt gaaggataaa ggggttgact tggcagtaac aaacctttca gaagaaggta
    21181 aaaaagctgt cgaagatgca aaagctaaaa tccttgatgg aagcgtaaaa gttcctgaaa
    21241 aataatggat ggaagtcatt tcttaggaag cggccaaggg ccgctttttt aagagttgag
    21301 acaaagtcat tttgtctcag taaagcttgc tactagacaa actagcaagt tttattgaaa
    21361 taaaataaga ctctgaaagg aagagcacat ggcacacgaa aatgtcattg agatgcgtga
    21421 tattaccaag gtgtttggtg gatttgttgc caacgacaaa atcaacttgc acctacgaaa
    21481 aggtgaaatt catgcacttt taggagaaaa tggggctggt aagtccacgc taatgaacat
    21541 gttagcaggc cttcttgaac caactagtgg tgaaatcgcg gtcaacggtc aagttgtcaa
    21601 tctcgactcc ccatctaaag cagctagctt gggaatcggg atggttcacc agcactttat
    21661 gttggttgaa gccttcacag tggttgaaaa catcatttta ggtagtgaat tgactaaaaa
    21721 tggtgtgcta gatatcgctg gagctagcaa agaaatcaag gctctttctg aacgttatgg
    21781 cttagctgtt gacccttctg ccaaggtagc agatatctca gttggagccc aacaacgtgt
    21841 agaaatttta aaaacacttt atcggggggc tgatatcctt atctttgacg aaccaacggc
    21901 tgttttgact ccatcagaaa ttgatgagtt gatggctatt atgaaaaatc ttgtcaaaga
    21961 aggaaaatca attatcttga ttacccacaa attggatgaa attcgcgcag tttctgaccg
    22021 tgttacagtt atccgtcgtg ggaaatcaat tgaaaccgtt gaaattacag gggctaccaa
    22081 tgctgatttg gcggaaatga tggtaggacg ttctgtttcc tttaaaacag agaagcaagc
    22141 ctctaaacca aaagaagtgg ttttgtctat caaagatttg gtggtcaatg aaaaccgtgg
    22201 tgttccagct gttaaaaatc tgtccttgga tgttcgtgct ggagagattg ttggtattgc
    22261 ggggattgat ggaaatggtc agtctgaact gattcaagcc attacaggtc ttcgtaaggt
    22321 tgaatctggt agcattgagc taaaaggaga ttcaattgta ggcttgcacc cacgtcagat
    22381 tacagaacta agtgttgggc acgttccaga agaccgtcac cgtgatggct tgattttgga
    22441 aatgatgata tctgaaaata ttgcccttca aacctactat aaagaaccac atagtaaaaa
    22501 tggaatttta aactattcaa atattacttc ttatgctaaa aagctgatgg aagagtttga
    22561 tgttcgcgtt gccagtgaat tagttcctgc agctgcactc tcaggaggaa atcaacaaaa
    22621 agcaattatt gctcgtgaaa ttgatcgagt tcctgatctc cttatcgtta gccagccaac
    22681 tcgtgggttg gatgtcggtg ccattgagta tatccacaaa cgcttgattg aagagcgtga
    22741 taatggcaag gctgtccttg ttgtcagctt tgaattggat gagattttaa acgtctcaga
    22801 ccgtattgcc gttatccacg atggtaagat tcaaggtatt gtatcaccag aaacaaccaa
    22861 taaacaagaa cttggtgtct tgatggctgg tggaaacttg ggaaaggaga agagtgatgt
    22921 ctaaaaaatt acaacaaatt tcggttccct tgatttctgt attcctagga attttactcg
    22981 gagccattgt catgtggatc ttcggttatg atgctatttg gggctacgaa gaattgttct
    23041 atacagcctt tggcagtctg cgtgggattg gagaaatctt ccgtgctatg ggtcctctgg
    23101 tcttgattgg tcttggtttt gccgttgcca gtcgagctgg tttctttaac gtcggacttc
    23161 ctggtcaggc tttggcaggt tggattctca gtggttggtt tgccttatcg catccagata
    23221 tgccccgtcc cttgatgatt ctggcaacta ttgtgattgc cttgattgct ggtgggcttg
    23281 tcggagcgat tccaggtatt cttagggcct atctagggac gtcagaggtt attgtaacta
    23341 tcatgatgaa ctacattgtc ttgtatgtag gaaatgcctt tatccatgcc ttccctaaag
    23401 actttatgca aagtacagat tcgaccattc gtgttggggc taatgcaacc taccagacac
    23461 cttggttgtc tgagttgact ggtaactcac ggatgaatat tggtattttc tttgccatca
    23521 ttgccgttgc agtcatttgg ttcatgctca agaaaacgac tcttggtttt gaaattcgcg
    23581 cagttggtct caatccacat gcttcagaat atgcgggtat ttctgcaaaa cggacgatta
    23641 tcctctcaat gattatttca ggtgccttgg caggtcttgg tggtgctgtt gaaggacttg
    23701 gaaccttcca gaacgtctat gttcaagggg catcattagc tgttggattt aacggaatgg
    23761 cggttagtct gcttgcagcc aactcaccaa tcggtattct ctttgcagcc ttcctatttg
    23821 gtgttctcca agttggagcc cctggtatga atgcggcgca ggtaccgtct gagcttgtta
    23881 gcattgtaac agcgtctatt atcttctttg tcagtgttca ttaccttatc gaacgctttg
    23941 tcaaaccgaa aaaacaagtt aaaggaggta agtaaagatg tctattacaa ccttgctcac
    24001 ccttttggta tcttctatgc tgatttactc agcacccctc atctttacaa gtattggtgg
    24061 tgttttctct gaacgtggtg gtgtggtaaa cgtcggcctt gaaggaatta tggttatggg
    24121 tgccttttct ggagttgtct ttaaccttga atttgcagaa caatttggag cagcaactcc
    24181 atggctatct ttgctagttg caggattggt tggatgcctc ttctctatca tccacgcagc
    24241 agcgacggtt catttccgtg cagaccatgt tgtcagcggt acggtattga acttgatggc
    24301 gccagccttg gctgttttct tagtcaaagt tctttataac aaaggacaaa ccgacaacct
    24361 aagtcagact tttggacgct ttgacttccc agtcttggca aatatcccag tgattggtga
    24421 tatcttcttc aagtcaacta gtctgcttgg ttatatcgcg attgccttct cattccttgc
    24481 ttggtttatc ctcttcaaga cccgatttgg tcttcgtctc cgctctgtag gtgaacatcc
    24541 tcaagcagcg gataccttgg gaatcaatgt ctacaagatg agatatctag gagttatcat
    24601 ttcaggtttc ctaggtggaa ttggcggagc gatttatgct caatccatct cagttaactt
    24661 ctcggtaaca actattgttg gacctggatt tattgctctt gctgcgatga ttttcggaaa
    24721 atggaatcca atcggagcca tgctatctag tctcttcttt gggctttcac aaagtttggc
    24781 tgttatcggt tctcaattgc cgttcctaca aggagtgcct acagtttatc ttcaaatcgc
    24841 accttatgtt ttgacaattc ttgtctcagc agccttcttt ggaaaagcag tcgcaccaaa
    24901 agcagatggt atcaactaca tcaaatcaaa ataagcatac aaaaaaacgt cagtccaatg
    24961 a
//
LOCUS       DAVDHZ010000032        21858 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000032 DAVDHZ010000000
VERSION     DAVDHZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.033"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(169..2049)
                     /gene="cbpE"
                     /locus_tag="VUR46_001540"
                     /gene_synonym="pce"
     CDS             complement(169..2049)
                     /gene="cbpE"
                     /locus_tag="VUR46_001540"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET5456940.1"
                     /translation="MKKKLTSLVLAGAFLSLSWYGNVQAQESSGNKIHFINVHEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWRQGINTTYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYKNETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGSLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNCLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYVVGWNKIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSNSEIKESNQVVKKDLENKETNQHESVASSSSSQDLTSSTSQSSEINANKSE
                     SE"
     gene            complement(2052..2939)
                     /locus_tag="VUR46_001541"
     CDS             complement(2052..2939)
                     /locus_tag="VUR46_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5456941.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDIPLEIVYQDEDVVVVNKPQGIVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYNLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGSRKTLKGHGQFLHAKTLGFTHPRTGKTM
                     EFTADIPEIFKETLERLRK"
     gene            complement(2929..3390)
                     /locus_tag="VUR46_001542"
     CDS             complement(2929..3390)
                     /locus_tag="VUR46_001542"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET5456942.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILSIAMLKEEINGN"
     gene            complement(3387..4295)
                     /locus_tag="VUR46_001543"
     CDS             complement(3387..4295)
                     /locus_tag="VUR46_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET5456943.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            4288..4485
                     /locus_tag="VUR46_001544"
                     /pseudo
     CDS             4288..4485
                     /locus_tag="VUR46_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(4537..5208)
                     /locus_tag="VUR46_001545"
     CDS             complement(4537..5208)
                     /locus_tag="VUR46_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5456944.1"
                     /translation="MKKRAIQILLVLSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLMESGVLLLAVIYLLVFAGKKTFHFKWQLRYFIYLLLGYITSYMSDFLFSYFISLSS
                     NQISLNETIEMIGRQELPYFLLIVCFIGPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(5262..5483)
                     /locus_tag="VUR46_001546"
     CDS             complement(5262..5483)
                     /locus_tag="VUR46_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET5456945.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            5755..6564
                     /locus_tag="VUR46_001547"
     CDS             5755..6564
                     /locus_tag="VUR46_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5456946.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(6745..7620)
                     /gene="aguB"
                     /locus_tag="VUR46_001548"
     CDS             complement(6745..7620)
                     /gene="aguB"
                     /locus_tag="VUR46_001548"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET5456947.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(7630..8715)
                     /gene="aguA"
                     /locus_tag="VUR46_001549"
     CDS             complement(7630..8715)
                     /gene="aguA"
                     /locus_tag="VUR46_001549"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET5456948.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVTDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(8712..9839)
                     /gene="nspC"
                     /locus_tag="VUR46_001550"
     CDS             complement(8712..9839)
                     /gene="nspC"
                     /locus_tag="VUR46_001550"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET5456949.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEITDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(9839..11098)
                     /locus_tag="VUR46_001551"
     CDS             complement(9839..11098)
                     /locus_tag="VUR46_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET5456950.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGQWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQDIVPIQFLKALLPAPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(11095..11955)
                     /gene="speE"
                     /locus_tag="VUR46_001552"
     CDS             complement(11095..11955)
                     /gene="speE"
                     /locus_tag="VUR46_001552"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET5456951.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMTVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GYTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQTFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTKYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            complement(11956..13416)
                     /locus_tag="VUR46_001553"
     CDS             complement(11956..13416)
                     /locus_tag="VUR46_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET5456952.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILS
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENVRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADIAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDFLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKEN"
     gene            14124..14819
                     /locus_tag="VUR46_001554"
     CDS             14124..14819
                     /locus_tag="VUR46_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET5456953.1"
                     /translation="MSETNHEIDSNFAGRLNILRAGVLGANDGIISIAGVVIGVASAT
                     SNIWIIFLSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDMELAKKSL
                     YAAYIQNGECETSAQLLTNKAFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFL
                     GSLPPMLSITIFPSEYRIPATVLIVGVALLLTGYTSARLGKDPTKTAMIRNLAIGLLT
                     MGVTFLLGQLFSI"
     gene            complement(15150..17138)
                     /locus_tag="VUR46_001555"
     CDS             complement(15150..17138)
                     /locus_tag="VUR46_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5456954.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGVLFDKLIFAFLLKLMKLKVELVATFQMNVVIAVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNASESFKKVMNPHDFGITGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNNHQFSVKEEFNTDFIVNHVPNQF
                     NILTADYNYLVVPNLQAFLDQFPDSAIYNQFYGGINVNASEEEQLKVAEEYDKYLDQF
                     NAQLNTEGSYVYGSNLSDASTQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     IDTTMMLIVTLSICAIFLIVYVLIFMITSRSYRKIVQM"
     gene            complement(17140..17898)
                     /locus_tag="VUR46_001556"
     CDS             complement(17140..17898)
                     /locus_tag="VUR46_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5456955.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPTRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            18326..18517
                     /locus_tag="VUR46_001557"
     CDS             18326..18517
                     /locus_tag="VUR46_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456956.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(18871..19143)
                     /locus_tag="VUR46_001558"
     CDS             complement(18871..19143)
                     /locus_tag="VUR46_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET5456957.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(19202..19651)
                     /locus_tag="VUR46_001559"
     CDS             complement(19202..19651)
                     /locus_tag="VUR46_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET5456958.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTKRYRCGLCRGKLLLVNQPED"
     gene            complement(19638..21767)
                     /locus_tag="VUR46_001560"
     CDS             complement(19638..21767)
                     /locus_tag="VUR46_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET5456959.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEVVLAKIQEQGKLTKELEEAILEAEKLADVEELY
                     LPYKEKRRTKANIAREAGLFPLARLILQNVADLEQEAEKFVCEGFATGKEALSGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQVKDESLDEKQVFQIYYDFSETVGNMQGYRT
                     LALNRGEKLGVLKVDFEHATDRILAFFAARFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASSESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         6477 a         4789 c         4012 g         6580 t
ORIGIN      
        1 caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttta tcgcccttaa
       61 tatcaaaaaa gaaaggacaa aatttgtcct ttctcgagct tagctgactt caacccacta
      121 cagttgacaa agagccgaaa aagaaggccc taaaaccttc ttttactact attctgattc
      181 cgatttgttt gcatttattt cagagctttg tgaagttgat gaagttaaat cttgactaga
      241 tgaagaactt gcaacacttt catgttgatt cgtttcttta ttttcaagat cttttttcac
      301 tacttgattg gattctttta tttctgaatt acttgtagtt ttaattgtag cagatttctc
      361 gatcggaaca tccactaacc aggcaccact tgaatccaca gtatagcctt ctggtgtctt
      421 accattcaca agtaattgac cattttcttt caagaagtac catttatcct tgtctttaat
      481 ccaacctata gctcgtgaac catctgtctt gtagaaatac caatcatttg cctttttaag
      541 ccagccttgc ttcatagctc ctgattcttc tagatagtaa tgatgtccag caacttctat
      601 ctcacctgtc ttcatgatac cagtagaatc catatagtac caggcttctt tatcttttac
      661 ccagcccgtt ttcatttccc ctgatggagc aaagtaatac cattgcccct tatattgaag
      721 ccaacctgtc ttcatagagc catcaacatc caaataatac cactgctctt tatcttgaat
      781 ccaaccaatt tccatctggt tttctttgtt aaaataatac cagattccat caattttctt
      841 ccaattttta gcagaagcac cagagtctgt caaatagaac caatgattgt tccatttttt
      901 ccattgattc tgtaacaaga tacccgtttg gttaaagtaa taccattcac cttcgatttt
      961 attccaaccg acaacatact ctcctgtaga atcaggcgct tgataccacc agttcccata
     1021 tgcactctta tgccaaccag cttgaaaact tggaatcggc ttgtaggatg ttgaaatatt
     1081 gacaaaaccg tcttttcgaa tatcaaaaac tgtcgcatca tagtctttgc tggctgcgtt
     1141 aattctctca attcctcgtt ctttgagaca attaacatac tcactatcaa caccattttt
     1201 ccaaggtaga ctatccgaag tttgaacaat caaactcgga ctcaaatttt taataaaatc
     1261 cttggtattt gatttgttgg tatcatggtg atgattaaac ttcatcaaat caacttttcc
     1321 aatgagagaa ccatacttgt cttctgctcc atgaacatta tctaagtcgc ccccaaggta
     1381 aattttcttg ccattgactt tcaccacgct aatcaaggaa ttggaattgt catcccaaat
     1441 tttctttaat tcacccgatg aatcagtttc atttttataa ttatagagct gaatatccat
     1501 gtccccaaac tgaaaatgag catccccttg tgtgatattt tgaataactg aaacaccttt
     1561 ttctgcagca gtctgtaaaa ccttatcata gccatacaga ttatcccata gacgttcaga
     1621 attagtaata cgactatcac tatatttctt aagatagact cggtcaactg gataggtaga
     1681 cagtaattca tcaacatttc caatatgatc actgtgggta tgggtcacca aaataaaatc
     1741 aagtttttgg acacccaatt ccttcaaacg acgaaagaca cggtctgtca gaacatgctt
     1801 ataagtggta ttgataccct gtctccatgg ataacgagaa tcacttccat ctgggaaatc
     1861 ataatcttct cctgtatcca ccatggcaaa atgtccattg ctttcaagaa taatcgcatc
     1921 actaccacct tcatgaacat ttataaagtg gattttattt cctgaacttt cttgagcttg
     1981 aacattccca taccatgata aacttaaaaa agcgcctgca agtactaaac tagttaattt
     2041 ctttttcatt cttacttcct caatctctcc aaggtttcct taaaaatctc tgggatatct
     2101 gctgtaaatt ccatggtctt acctgttctc ggatgagtaa accctaaagt cttagcatga
     2161 agaaattgtc catgtccttt cagagtcttt cgagaaccat agacttcatc cccagcgact
     2221 ggatgaccga tgtaagccat gtggacacga atctgatgag tgcgccctgt ctccagttgc
     2281 aattccacta agttataatc gccaaagcgt tccaagacgt gaaaacgcgt cactgcaggt
     2341 ttccctttag cagttacagc ctgtttctta cggtcttttt cactccggcc aatcggcgct
     2401 tcaattacac cacgatcatt aggcagattt ccatgaacaa tcgcccaata tttgcggaga
     2461 gactttttat ccttgagttc ttgggcaagt gctagatgcg catcatcgtt tttagcaatc
     2521 atgagaagac ctgacgtatc cttatcaata cggtgaacaa ttcctggacg cagaacccca
     2581 ttgatacccg acaagtcctt aatatgatac atgagggcat ttactagggt cccactggta
     2641 tgaccagcac tcggatgcac aactatcccc tgaggtttgt taacgacaac cacatcctca
     2701 tcttggtaga ctatttctag cggaatatcc tcagccacat actctaatac ctctggttct
     2761 ggcacatggt aagtgacgac atcaccctct tggactgtgt atttagcttt cttgacttga
     2821 ccattgacca agacctggcc tgatttaatt tgttcattcg caagactgcg tgataattct
     2881 gtcaaatctg ataaagcctt atccaaacgc agaccaccag tttcaatttt aatttccatt
     2941 tatttcctct tttagcattg caatcgataa aataatcact ccaaccgtca gatagctatc
     3001 tgccacattg aaaattgcaa agttgataaa gtcaaggtgg aacatatcca caacaaagcc
     3061 ctgactgacc ctatcaataa agtttccaag accacccgcg attatcagag tcaaacccaa
     3121 gaccatccag aatgagtcct ccatgtgttt atgtaaatac caaatggcac ctatcacgac
     3181 aaccagagta atgacagcga ataacaactg ctgatcttgt aagatagaaa aggctgcacc
     3241 tcgattttgc aggtaggtca agctaacgaa attgggaatc caggagcgca cttcacccag
     3301 tggaatctgc tggacgatat aggatttgac caactgatcc agcccaatca aaagcagtac
     3361 aatgactgcc actattgctc tttttttcat gatttcctct tttgatcaaa atattcttgc
     3421 atgacttcta cgaagagagt cccagcttga ctaagctcca cttcttcgcg tttaacatag
     3481 accatgcggt tatctaggtt atccttgaga cgaataactg taatgccatt aacactgtca
     3541 ctatctaaaa atccagaacc tgtcgcatag gcgtccgtcc gttccaaaat accattcaaa
     3601 gtggcacggt ctgtcacatt aaacatctgt gagcttgcac tggtatcgac aaagttctct
     3661 gaataataaa ggtactcgtc tttctcttga gtgaaacgaa ccgttggtaa atccgctaaa
     3721 tcctccatga ctaattcctc tttctgggct aaaggatgac cctcacggag ataaatatgg
     3781 gtatggaaag gaatcaattc gatgacctcc agacctaatt tttcaacccg ttgcataatc
     3841 ccctttttat tttgattgtt gaggtagata atcccaatct cactatgccc ttgcgccact
     3901 tcatctaata tttgaacagt agttgattca aaaatacgga agttcttata gtcaggatag
     3961 cgctctgaaa aggccgtaat agttggtggc aagaagtcat agtgctggct agcaacggaa
     4021 aattcatctt tttcttcttc aggattggca tactgatttt gaaaaatatc aaatccttta
     4081 accaattctt gcgctttttc ataaaattcc atcccacgac gggtcaagaa agtccctgag
     4141 ctggtccgac ggaaaatctt aaaacccaac tctttttcca aatcacgaac agaaatagac
     4201 agactcggct gactaacata catcttttca gcagcttcac ggaaagtacc actattggca
     4261 atggccacaa catagcgtaa ttgttgaatg ttcatcttct acccctaact tctttatctt
     4321 ttcattatac catattttag aagttttcca aaaaggaaaa aagaacatcc tattcttctt
     4381 aactatcttc actatctgcc tttctcaagc caaccttatt ttcaaaatca attcaaaaaa
     4441 ataactggat acacaccact acaatatcga aaagaaaaac gttgactatt tgtgaaaaaa
     4501 gaaaatgccg gaaagttccg acattatttt agtaagctaa cttcctgaaa ataggagcaa
     4561 ccacacatcc cagaaggcag tgatattaat gagaatatga actagtattg gatagtagag
     4621 atttttagtc atgcgataca atagagctaa aataagacct ccactagcat aaatgaaaaa
     4681 agcaagagga gttaaagcaa aattgatatg aatataaccg aaaataatag cagaaagcaa
     4741 gacatctccg taccaaggcg agtttttgaa aaaggttgtc ataagcacac cgcgataaat
     4801 caattcctca gcaatagggc cgatgaagca aacgatgagc aaaaaatagg gtaattcctg
     4861 tctccctatc atttctatcg tttcattcaa agaaatttga tttgaagaca gagatatgaa
     4921 atacgaaaag agaaagtcag acatatacga agtgatgtaa cccagtaaaa ggtagataaa
     4981 atacctcagc tgccacttga aatgaaaagt tttctttcct gcaaaaacta gtagatagat
     5041 gaccgctaat aaaagaactc cactctccat caaaagcaga atctgaaaaa attcacgact
     5101 tgctggtaga tagggctttg cgagataatt gaaaagcctc caaaaccaag ttgatttgta
     5161 aaaaattaag gacaatacta gtaaaatttg aatagctcgt tttttcatat taaatcctct
     5221 gttttctccc cttgtttctt catattccta ataaatttta cttaaaatct cgcagcactt
     5281 cctttgcaaa gatgattgcc tcctccaata tatcctaaat cataggtgcc tctgggacaa
     5341 aatccatgaa ccggcagagt taatactggt tctatttccc aatcgtacct accattagga
     5401 tttttaccat agggatctgc tccaccttgt atcagctcta attcttcatt tgttagattt
     5461 atattttttg tcattaaaat catgatatat ttcctccatt attcttcaga ttagttgagt
     5521 aatctgatac tcatacctac ttacaaaaaa actattatat taagttggtt ttttaatttg
     5581 tctagttgca acattgacaa acatagcata gcatatcttt gcgaaatatc ctcttcaaat
     5641 catgaattgt catcaaaaca tcttaaacta taaaatcaat tagtctcaag ctttctatca
     5701 atttcttctc caaaatatgc tataataata gcaaaagata aagaaggaag acctatgatt
     5761 aaactactag ccttggatat ggacggcacc ctcctcaatg aagccaagga aatcccacaa
     5821 gctcacatta ctgctattca caaagccatt gaaaaaggtg tcaaactggt tctctgtacg
     5881 ggtcgccccc ttttcggtgt cctcccctac tacaaaaaac tggagcttga cctccagaac
     5941 gaatatatta ttgttaacaa cggttgttca actcaccaga ctagcgactg gggcttggtt
     6001 gactggcaag aactgagtcc agctgacatc gaatacctct atgaccttgc tgaaaagagt
     6061 gatgttcagt tgacactttt tgacgagtca cattattttg ttctcggtgg caaacccaat
     6121 caagttattg aaaatgatgc taaactagta ttttcagacc tgactgaaat ttctcttgaa
     6181 gaagcgacta gtggaaagtt ccggatgttc caaggtatgt ttttaggaac aaaagaacaa
     6241 acagacgatt ttgagcagcg ttttgctgaa gagctttgcc aacgattcag tggagttcgt
     6301 tcgcagcctg tcatttatga agcaatgccg cttggaacga caaaggctac tgctctttca
     6361 cgactagctg agattttgaa gattgattcc tcagagatta tggccatggg cgatgctaat
     6421 aacgatatcg aaatgctcca gtttgcaggg cttgggattg caatgggaaa tgccagcgat
     6481 tatgtcaaat ctcttgcgga tgccgttaca tcaagcaacg aagaagacgg cgttgcgcgt
     6541 gctattgaga aatatattct ataaaaaaga aaagcaaata gacagaagtt actgctattt
     6601 gcttttttgc taatatttta aaatacggac taatcaatag acaagaatag cgaatcataa
     6661 aaatcgattt actagatgcc atagtatctt atagttgcta ataagaagtt agtctagcag
     6721 aatgaatctc tcatttctcc cacactaatc tgtaatttgt ctatacattt ctggtcttct
     6781 atctcgaaac aagccccagt ttaggcgttc acttgctccc ttgtctaggt cataagtagc
     6841 taacagaaca gcttcttctt gtctttcagc tcgttctaga atagctcctg tttcatccgt
     6901 cataaaggag gaaccgtaga agtcaagact ggaactctgt ccgccatttt cctcactagg
     6961 agtaacctcc tctaaaccat aacgattggc tgcgatgact ggaacaatat tcgctgctgc
     7021 gtgcccttgc atagtacgtt gccagtgacc acaactatct gtatccaaaa ttggctctga
     7081 accgatagct gtaggataaa agagcaattc agcaccattc aatgcaagac agcgcgctgt
     7141 ttcagggaac cattgatccc aacagatacc gataccaatc ttagcatagc gagtattcca
     7201 gaccttgaaa ccagtgttac caggcgtgaa atagaatttt tcttgataat aatggtcatc
     7261 tggtatatgg gtctttcgat aaacgcccag cacttcccca tctgcatcaa tgacggcaat
     7321 agagttatac aagacattac catctttttc atagaaactg attggtaaaa caacttgtag
     7381 ttccttagca atcaccttaa aatgctgaat ggcagtattt tccgctacag attgggcata
     7441 ctggtagtag tcatactgac gttcctgaca gaaataggga tgttcaaaca actcgggcaa
     7501 gagaataatt tgggctcctt gctcagcagc ctgacgtact aaacgctctg cggtttggat
     7561 atttgttgcc acatccttag cgcattgcat ctgaatggtt gcaactctta catttctcat
     7621 ctttttctcc tattctggaa tttgttgggt gatacagtgg atattgccac cacctaagag
     7681 aatatctctg gctggtattc cgacaacttt acggtctggg aaacacttgc tgaggatatc
     7741 taaggccact tggtcgttta catcctcaaa ctgtggaacc aagacagcct tgttggcgat
     7801 ataaaagttt acgtaggaag ctgctagtcg ttcacctgcg tatcgctttt cttctccttc
     7861 ttcatagatg tagcctggca aatcttcttc tgtcacaact tgtcgaactg cagggatagg
     7921 caatttatga atggtgaagt gacaaccttt tgcatctgtt tcctgttcta agagttcgag
     7981 atctgctttt gacatggcat actggggatc attttcgtca tctgtccaag ccaaaacaag
     8041 ctcagcagga ccaacaaagg cagcaacatt atcgacgtgt tcattggttt catcctgata
     8101 aataccataa ggaagccaaa taactttttc agcaccaaga ctttctaata atgtgttttc
     8161 aatctcctct ttagtcaggt taggattgcg accaggacta agcaagcaac tttcagttac
     8221 gagaatagtt ccttgaccat cgctatggat tgcgcctcct tccagtacaa aaggtttagc
     8281 atcatagaca ggcctttcca aggcctcagc aaaacgactg gctacttggt catcctcttc
     8341 ataatcttga taaagaccat cataggtgcc tccccaagca ttaaaggccc aatccacggc
     8401 taatttctta cctttatcag tgacgagaat ggttgggcca gtatcacgcg cccaggcatc
     8461 attggtggga atgtctaaat aaacaacctt gtctccaaga taggattggg cttcagatag
     8521 ataggcctgc tccaccaaaa gatagactct ttccccttct gctatggtct cgatgatctg
     8581 agtaaatgct cttttagcag cctttccttg aaaaggccat gatcctggtc gagtcggcca
     8641 tatcatgagg gtaccatgat ggggttcgta ctctgctggc atgtgatagc ctaatttttt
     8701 tggactgtcc atcatgataa tctcccttta aagtcttgat agccaaaagc tttgagtaag
     8761 ctacagtctc cctgttcgtc catgagatag agacttggca atccaatacc attaaaggta
     8821 ttatttttga caaaagaata aatggccatg tcttgaaaat aaagtctgtc tccgatttgg
     8881 actggatttt caaaactata atcaccaatc acatcgcccg tcagacaggt attagaagaa
     8941 agtctgtagg tatgggcttt ttcctgtgcc tcaaagccat ttctcaaagg tggacgatag
     9001 ggcatctcaa gtacatcagg catatggcag gtcgcagagg cgtctaaaac caagatttcc
     9061 ataccgtttt ctacaatatc taatacctca gttgctaaat aacccgcatt aagcgcaatg
     9121 gcttcaccag gctcgatata gatttcaaga ttgtaagttt ttcggatacg cttgatttct
     9181 gaaatcagca aatccacatc gtaaccttct cttgtaatat gatgaccacc acccatattg
     9241 agccatttta cctcatgtaa gtagggacca aactgttctt ctactgcttt caaagttgtt
     9301 tgtaaatcat ctgctccctg ctcgcaaagg gtatgaaaat gaagtccgtc aaccaaatcc
     9361 agcaaatcac tcggaatctt gtctatagta actccaaagc gagaacctgg tgcacaaggg
     9421 tcatagagcg cgtgatctcc ttgagttgaa cactgagggt tgaggcgcaa accaacactg
     9481 acaccagcct ctcgacaacg cggaccgtgt ttacgcaact gtctctctga gttaaagacg
     9541 atatggtccg ttatctctag caattcctcc aagtctgcat ccttgaaagc aggcgcaaat
     9601 acatggactt caccaggaaa ttcttccctt gccaatttgg cctcatagag tccactagct
     9661 gtcgtacctg atagatactg gctaatcaag ggataagttt tgtagaggga atatgccttc
     9721 tgggcaagca agaccttgca accggcctct tcttgtacat attgtagaat gcggcaatta
     9781 gcttctaact tggccaagtc aataacatag gctggtgttg gtacttgttc taacttcatt
     9841 agtccaccat ttgtggattt tcaaccacaa cccatggcaa accatactca ttcaaagctt
     9901 ccatgaatgg atctggatct aactcctcaa ggttatacac tccagcttgt ttccaagttc
     9961 cgttcatgac taattttgtc ccaatcatgg ctggaactcc tgtcgtgtat gaaattgctt
    10021 gtgacccgac ttctgcatag cactcttgat ggtcgcaaac attgtagatg tagatagtct
    10081 tttcaacgcc atctttgaca cctgtaaaga tacatccaat attggttttt ccgactgtac
    10141 gtggcccaag actggcaggg gctggaagca aggcttttaa gaattgaatc ggaacgatgt
    10201 cttgtccatt gaagttaatg gtatccgtac gaaggagtcc tacattttca agacatttca
    10261 tatgtgtcaa gtaagattga ccaaaagtca taaagaaacg aatgcgtttg actccaggaa
    10321 tgttcttggc cagcgattca atttcttcat ggtgaaggag atacatatct ttttgtccaa
    10381 cttgagggaa atcgtactca cgtttgatag acatagcttc gacttcgacc cattgtccat
    10441 cttcccaata agaacctggc gcagaaacct cacggagatt aatttctggg ttgaagttgg
    10501 ttgcaaatgg ataaccgtgg tcaccgccat tacagtctaa aatgtcgata taatggattt
    10561 catcaaaata gtgtttgagg gcataagctg aaaagacact agttacacct gggtcaaaac
    10621 cagaaccaag aagagcagtc aagcctgctt ctttgaattt ctcttgataa gcccactgcc
    10681 atgagtagtc aaagtaggct gtaaaaccaa gttccttaca acgtttttcg tagatagcac
    10741 gccactcagg gtcttctgtg tcttctgctt cgtagttggc tgtatcgata tagtgaacac
    10801 ctgttgccaa acaagcatcc ataatggtta aatcttgata aggcagagct acattcaaaa
    10861 cagcttctgg tttgtagctt tcaatcaggg caatcacttc ttcaaccttg tcagcatcaa
    10921 gagcagctgt ctcaatcttt gtacttgttt tgccttccag tttagctttc aagtcatcac
    10981 attttgactt ggtacggcta gcaatcataa tctctgtaaa tgtttcgcta tcttgacaaa
    11041 tcttcgaaat agcaacttgg gcaacgcccc cacaaccaat aactagtaaa cgactcattt
    11101 ttttccttcc tcttcttcta aaatgtcttc tacatacttg ggcaacataa aggctcctac
    11161 atgtaagttt gcagtgtagt attttgtgaa aagctggcgt tttttccagc cttccttgtc
    11221 aaaatctttg acaggatggt attttttcga tgcaaatcca aataaccaat agcccgccgg
    11281 actggtaggg atatgggctt ggtagacacg actaattgga aaggtctgat tgacctttcg
    11341 gtgcatgctt cggcaagccg actcatcctc atcaaagaag ggactcccat gctggtaaat
    11401 cataatgccg tcttccttca gagctcgata actattaccg tagaattcct tagtaaagag
    11461 cccttccgta tagccaaagg gatctgtcgc atcgttgatg ataatatcat aatcatcttc
    11521 gcagtttcgc aaaaaacgta gcccattttg ataataaatg gtaacacgtg gatcatctag
    11581 ccctgcagca aagtctggaa aatactcacg acaaacctca accaacattt catcaggttc
    11641 tacaatatcg atttgttcca attctggata aagtgttaat acttgagcaa caccaccgtc
    11701 accaccccca ataaccaaga ctttcttggg atttgggtgg acagtcatgg gaacatgaac
    11761 ggtcatttca ttgtagacaa agtcatccgc atctgaaaat aagacgtgcc catttaaaat
    11821 cagtattttc ccaaaagctg gtgtatccaa gacttcgata tcttgccatt cactttttcc
    11881 agcgtagagt tgcttggctg ttctcaggga caattttaca tctggagtat gaacttcaga
    11941 aaaccataaa tccatctagt tctcctttct cttaatgacg ttgatgtgat tgacctcagg
    12001 atcttccgtc ccttggaggg aacaaccacg ttccttggca aattggatat agtctacaat
    12061 ttctcgtgta atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac
    12121 aaattctcca cagacttgtc caacagattc gtccaaggtt aaactttttc tctctgaata
    12181 gaaggcttcc tgaggagata acaccaactc gggctgaata tattctcctg ctatcaagtc
    12241 cttcccatct cgtgaataga gtctctttat gtcagccaaa gcaccgacca agcgctcgat
    12301 gtcttggatg cggtcaccaa tcgaaatata ggccaagata ttgccaatat caccaaactc
    12361 aatctgaatg tcgtattcgt ctcgtaggaa gtcataaacc tcgatacctg ttaagccaat
    12421 accctgagtg taaactgaca gcttggttac atcaaaatca cagaccgaca caccatctat
    12481 taactctttt gagtaggcat agtatccacc aatagcattg atttcacgac gagcgtactc
    12541 ggatagctca atgaccttct caaacgactc tttaccacga agggccaagt tgcgacgtga
    12601 aatatccaaa ctagccatca acaggtaaga agcagatgtt gattgggtca ggttgatgat
    12661 ctgacgaacg tactcgggat tcatctgctc tccgattaaa agaagcgaac tttgtgtcaa
    12721 actcccacca gacttatgca tggagactgc tgctatatca gcacctgcat ccatagcaga
    12781 aattggaagt ttatctgtaa aatgcaaatg cgctccgtgg gcttcatcta ctaaaaccat
    12841 cataccagct tcatgagcca tttctgtcaa cccctttagg tctgaacaga ttccgtagta
    12901 agtaggattg ttaatcaaaa tggccttggc atctggatgg tcttttatgg cctgtgctac
    12961 tcgaacattt tcaagaccta aagcgatacc aatcttagga tccacactca tctcgatata
    13021 gatgggaatg gcaccacata gaaccagcgc attgatagca gatttatgga catttcgtgg
    13081 cagaataatc ttatctcctg ccttacaggt tgacagaatc atagtctgca ccgatgaggt
    13141 tgttccccct atcattagaa aagcatggct agctccaaaa gcatctgcag ccagctcctc
    13201 tgcatcacga ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac
    13261 atcaatgcct acacattttt ctcctaagag ttcgacaagt tctggatttc ctcgtccacg
    13321 cttgtgacct ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc
    13381 ataaattggg gcttggtttt gatctaactc cttcaagaca tactcctttc aatattttta
    13441 ggaccttatg aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc
    13501 tgctctgcaa tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg
    13561 tttcctaact ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt
    13621 gtgctttcac cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa
    13681 aagtaggctt ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc
    13741 tgcctgtccg taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt
    13801 tctaagcttt attactatat catgttttta agaacttgta aagcggttta cgaaaaaaat
    13861 ataaaaaagt tcgcaaaata tttggatttt atttgattta atactactta ttttattgta
    13921 aacgattata aagtgaacaa aatgtttatc gtatttaatt taaaattttt atgctattct
    13981 atactcttta ccttcggtgt ttgatctatc agaaaagatg tcgacatttt tatatcatta
    14041 aaatcgtgca acttttttca gatactttta aaagattgat ttccctatat ttttccttta
    14101 tactggataa aaaggagatt agtatgtcag aaacaaatca cgaaatcgat tcaaattttg
    14161 caggtcgttt aaatatcctg cgtgcgggtg ttcttggtgc taatgatggg attatttcca
    14221 ttgctggtgt ggttattggg gttgccagtg ctacaagcaa tatctggatt atctttttgt
    14281 caggttttgc ggctatctta gctggtgcct tttcaatggc aggtggagaa tatgtatccg
    14341 tttcaactcc aaaagatacc gaggaagctg ccgtttcgcg agaaaaactc ttgctagacc
    14401 aagatatgga actagccaaa aaatctctct atgcagccta tatccaaaat ggagaatgcg
    14461 aaacctctgc ccaactcttg accaacaagg cctttcttaa aaatccactc aaggctctgg
    14521 tagaagaaaa atatgggatt gagtatgaag aatttactaa tccttggcac gctgctattt
    14581 ctagcttcgt tgcctttttc cttggtagct taccaccaat gctttcaatt accattttcc
    14641 caagtgaata ccgcatccct gctactgtcc ttatcgtcgg tgtggccctt cttctcactg
    14701 gttacactag tgccagactt ggaaaggatc caaccaaaac agctatgatt cggaacctag
    14761 ctattggtct cttgaccatg ggagttacct ttttgctagg acaacttttc agcatttaat
    14821 actcttcgaa aatcaaattc aaaccacgtc agcttcgcct tgccgtatat atggttactg
    14881 acttcgtcag ttttatctgc aacctcaaaa cagtgttttg agctgacttc gtcagtttta
    14941 tctgcaacct caaaacagtg ttttgagctg acttcgtcag ttctatctgc aacctcaaag
    15001 cagtgctttg agctgacttc gtcagttcta tctgcaacct caaagcagtg ctttgagcaa
    15061 cctgcggcta gcttcctagt ttactttttg attttcattg agtataaaat acaagaaata
    15121 cctcgatttt gaagtcgagg tatctttttt tacatttgta caatcttgcg atagcttctt
    15181 gaagtaatca tgaaaatcag cacatagacg atgaggaaga tagcgcagat agacaaggtc
    15241 acaatcaaca tcatagtcgt atctattaca ccaatcactt ttaaaatcag actaagcata
    15301 tggtaggcaa aggctagatg taggaaggca aagagcaaag gaaggaagaa tacagttaaa
    15361 acctgtttgt tgatggtttg cttgatttgc ttttgatcca aaccgacttt ctgcaagata
    15421 ataaagcgct cacggtcttc gtagccttca gaaatttgtt tgtagtagat gaccagaacg
    15481 gttccgacca taaagataat ggataggaaa ataccgataa agaagacacc accaaatagg
    15541 gcactcatct gagtactagc atctgataaa ttactaccat aaacatagct accttcagtg
    15601 tttaattgag cattaaattg atcgaggtat ttatcatact cctcagcgac cttgagttgt
    15661 tcttcttcac tggcatttac atttatgcca ccgtaaaact gattatagat agccgaatct
    15721 gggaattgat ccaaaaaggc ttgtaaatta ggtacaacaa ggtaattgta atcagcagtc
    15781 aaaatattaa actgatttgg gacatggttc acaataaaat ctgtattaaa ttcttctttt
    15841 acagaaaatt gatggttatt tagagttaga gctttctgtc ctttcagtcc gtcatttttg
    15901 gcaaaaagac cgacctcatt tcctgataga gaaagttttt gaccagtcat attttcataa
    15961 tctttttggt caaataccat gaaaactgtt tttggttgga cacggttttg tcctttttca
    16021 aaaatagtta acttggttcc ttcttgattt gcaataccaa agttactgta acgaagcact
    16081 tctttctctt tgacactata acctttgtca cttgcaaact ggctcaagag tttgtccaaa
    16141 tcttcttttt caacattttg tccagtaatt ccaaagtcat gcggattcat cactttttta
    16201 aaggattctg aagcattgaa aatgcttgtc gctgctgaca tggttaccaa aaccattgtt
    16261 gacaaaatag cgatggttgc tagtccaacc gcatttttct tcatacggaa aatcaagtta
    16321 gacactgaga tgaggttatt aggttggtaa tagtatttct tgtttttctt taagatttgt
    16381 aggaagactg taatccctgc attaaacaat agataagtac caaagataac cagcaaaaca
    16441 gctaggaaga aagttgttag ggctgtaaga ggatcggtta ccgtaagggc aagataatag
    16501 ccaatcccta aacttatgga accaagaata gtttggagag gtaggaaacg acctcttttc
    16561 tctccgcttg ctttctcacg cgagagctgg agggcattca tacgggcgat tcgaagggca
    16621 ttcaggaaca tgaggcctag gaaaatcaat ccaaagacaa gaagtactgc aatgacaaca
    16681 ttcatttgga aggtagcgac tagttctacc tttaatttca tcagtttgag taggaaagcg
    16741 aaaatcaact tatcaaacaa gactccaata ccgatacctg ctccaacagt tagaatccca
    16801 aatagcacta actccttaaa ggtcatactg atcagatggc gcttttccaa tcccaacatg
    16861 ccataaattc ccagttcctt agaacgattt ttcatgacaa aactattggc atagaggacg
    16921 ataatggctg acgcaagggt gacgacaaac ataccaaatc caagtgtagc ctgaatggtt
    16981 gttcctccac ggatttcagc aatctttgga ttgaaagtta gagagtaaaa gagataggtg
    17041 acagtgaccg ccaagagaac agccagcgca aaaggatagt agagtttgcg gtttttaatc
    17101 aagttcgata ccgctaactt attggttaat cgaaacatac taattcacct cgcttgccat
    17161 gacagtcaag gtatcagaga tctcttggaa catctgacgt tctgtcttct ctccacggta
    17221 gatttgattg taaagaatgc catctttgat aaagagtaca cgtttagctc tgcttgctgc
    17281 tgctgttgag tgggttacca tgagaatggt ttggccgcgc tcattgattt catcaaaaac
    17341 atcaagtaag gctgcagatg acttggaatc aagggctcct gttggctcgt ccgcaaggag
    17401 aatttcaggt tctgtgatga tggcgcgggc tactgctaca cgctgtttct gaccaccaga
    17461 aatctcgtaa gggtacttct cttgcaattg gttaataccc agattctcag ctgtcaccac
    17521 caatttcttc atcatctccg ttataggtct tcttgacaag acaagcggaa gcaagatatt
    17581 gtccttaaca gacagagtat ctagcaagtt aaagtcttgg aagacaaatc ctagcttttc
    17641 acgccggaaa ctagaagcct gtgaattttt aatagttgcg gtgtcagttc cattcaagta
    17701 aacctgccca cgagttggtt tatccaacat agctagaata ttgagaagag ttgatttacc
    17761 agaaccagac tcacccatga tggcaacgta gtcacccttt tctacggtaa agtgaatatc
    17821 cttgagggcc tctacttggt tgccctgaaa acgtgtttta taaatttttt gaacgtgttt
    17881 tacatctaaa agtgtcatga gaatctcctt tcttaatatc ccatcaaatg aaatgtagct
    17941 tgcatcatag tgcatcccag ctgaacgcgc tcaatttctt tgtgacttgg ttttctagtt
    18001 ttcttatgta agatttgttt catgatgtta ctcctttgtt ctttatgagt ctagtttaca
    18061 tcaaaaaaag accgcttgcc ataacctaac cttacaaaag agactttaat cttacatttt
    18121 tgtaagattg ggtgaaatat aagcaaaatt acttagaaaa tgatttgatt tcctattttt
    18181 aaagttgtaa aatataagtg tgaaaaagct tactttgaaa aggaggaagc gggaactaac
    18241 attttagtaa gcttacctag ataacatacc attcaattta acacttgcaa gtcgttcaac
    18301 ctataaggaa agaaggtgcg ctttaatgaa acacaaagaa catatactca tcggacttct
    18361 ctatctgctc tctccattca tcggtcagct cttagttgaa cacacacact ttatcagtac
    18421 agaatttacc ggcactgctt atgttatttg ctggttatca gttgttatca gcatccacca
    18481 tttttccaaa aatgtattgt ctcaacagca aaaatagatt aaaaaactgc gtttaaatta
    18541 ctgcttttat agtaaaatga aataagaaca ggacaaatcg atcaggacag tcaaatcgat
    18601 ttctaacaat tttttagaag tataggtgtc ctattctagt tccaatccac tatagtttgt
    18661 ggatgaagct ggcgaaatat tattaatact attcaaaaat caaagtgcaa actatatcaa
    18721 cttcacattg ccgactaaat tacagcctgc ggctggcttc ctagtttgca ctttgatttt
    18781 tattgagtat aaaagtaaaa aagctttaaa tcaagcagtt tagactattg atttaaagct
    18841 ttttgcgtat tccaaatctt ttgtaaaacc tcaccaaaac cagccttcat tatcgtcaat
    18901 ggcttgagct tctttgcgtt tacgtgggcc tgttccgtac atttctgctt cgatttcttc
    18961 cttggttggc atgatagaag ctaggatgat atagataatc accccaagtc caaagtttgc
    19021 gactgtaaaa atggcaaaca gaaaacgtac aagggtaaca tcaaagttcc acttgtctga
    19081 cagacctgct aaaactcctg aaatcatgcg atttcgtctc attttataaa acttactgtt
    19141 catgatattt cctctttctg ctaggttaga catagtatat cacggatagg ctcggctttc
    19201 atcagtcctc aggctgattt actaatagca actttcctcg acaaagtcca cagcgatagc
    19261 gtttggtatc aatcctacgc ttacgctgat aagtttgctg gcaggattgg caacgataga
    19321 gcttgattgg cttggagtta ctattgggca aggatggtac aaaccgtaat ccatccactg
    19381 ctttcaacag ttccttaaaa tcccgatcct tgtgttgata gcctttccct tgaaaataga
    19441 ggtgataatg acagagttca tgtcggacaa ttttcctaaa aacgtccaac cccagttcct
    19501 gataaacctt gggattaaaa tccaaatgcc catctttggg gaaaaatcgc ccacctgtcg
    19561 aacgtagacg cctattccac tggacatgat ggataaaagg tctgccgaag tcttctagtg
    19621 aaacctgctt gacgtaatca gtcagtttca tttggagcta ggagagacag attaactttt
    19681 tcacgttcag tatcaatttt cttaacccaa acgctcacca aatctccaac tgccaccact
    19741 tgactagggt gtttgataaa cttgcgactc atatgggaaa tatggatgag accgtcctca
    19801 tgaattccga tatcaacaaa agcaccgaaa tcaacaacgt tacgcaccac tccttctagc
    19861 ttttgtccaa ccactaagtc cttgatatct aggacatctt gacggagaac tggagcatca
    19921 aaggaatcac ggaaatctcg acctggtttg agaagatctg caatgatatc tttaagagtt
    19981 tctggaccaa ggtctaactc ttgcgccatt tccttgactg aaagcgactt gagtttgctt
    20041 tgggcctctt cattcagatc cttaatgtcc aagcatttga agagttcctt aacggcagcg
    20101 taattttctg ggtgaactcc tgtattatca aggatattgc tactttcagg gatacggagg
    20161 aaaccagcag cctgttcaaa agccttggcc cccaaacgag gaactttctt gatttgggag
    20221 cgtgaagtga tttttccctc ttcctcacgg tatttgacga tattttcaga aatggtttta
    20281 ttgagtccag ctacgtgtga aagaagagct gggctagctg tattgacatt gacaccaact
    20341 tggttaacca ctgtatcgac aacaaagtcc agactctcag atagtttctt ctgactgaca
    20401 tcgtgttggt attgaccgac accaattgac ttaggatcga ttttgaccaa ttccgcaaga
    20461 ggatcttgca aacgacgggc gatagaaatg gcagagcgtt tttcaacggt caagtctgga
    20521 aactcctgac gagcaagttc gctggcagaa tagacagaag caccactttc attaacgata
    20581 acatagctga cttcagggaa atctttcaga acttccgcta caaaagcttc actttcacta
    20641 ctggccgttc catttccaat ggcaataatc tctacaccgt attgaccaat taaatctgct
    20701 aaatctttct tggcttcttc gatttgacga gctgatgctg gtttaacagg ataaataacc
    20761 tgagttgtca gcatttttcc tgttgcatcc acgacagcta gcttggcacc tgtacgaaag
    20821 gctgggtcaa acccaagaac cacgcgccct ttcagtggag caaccaagag gagattgcgt
    20881 agattgtcag aaaagagttg gatagctcct tcttctgctt tttcagtcaa ttctgtccga
    20941 atacgacgct cgatagcagg caagaccttc ttcttaacag attgctgaac cacttcatca
    21001 atataggcat tttttacctt gaaacgagca gcaaagaagg caagaatacg gtccgtcgca
    21061 tgttcaaagt cgaccttcaa gacacctagc ttctccccgc gattgagagc caaggtacga
    21121 taaccctgca tgttcccaac tgtctcagaa aaatcataat aaatctgaaa aacctgcttt
    21181 tcatcaagac tttcatcctt gacttgagaa gtgagtttag agtgtctcag cacttcctga
    21241 taagtcatgg aacgcaaggt cacatcttcc gataaggctt cgaccaaaat atcaactgca
    21301 ccagacaagg cttccttacc agtcgcaaat ccttcacaga caaacttctc agcctcttgt
    21361 tctaagtcag ctacattctg caaaatcaag cgagcaagtg ggaagaggcc agcttcacgg
    21421 gcaatgttcg ccttggttcg acgtttttcc ttgtatggaa gatagagttc ttctacgtct
    21481 gctagttttt cggcttctaa gatagcttct tccaattcct tagtcagctt gccttgttct
    21541 tgaattttag ctaaaacaac ttccttacgg tcatttagat ttgtcagact tttatccaag
    21601 tcaataatgg ccttaatcgc cacctcatcc agactaccag tcatgtcctt acgataacgc
    21661 gcgataaagg gaatagtcgc cccttcagct gtcaaactta gaacggtatc aatttgcttt
    21721 aaagtcactc ccaaatcttg ggagattttt tcatattttt tatccatgaa tctattatac
    21781 cacaagctgg aaggctttct ccaatccttt tcatactcaa taaaaatcaa aaagcaaact
    21841 aggaagctag ccgcaggc
//
LOCUS       DAVDHZ010000033        21817 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000033 DAVDHZ010000000
VERSION     DAVDHZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.034"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            129..809
                     /locus_tag="VUR46_001561"
     CDS             129..809
                     /locus_tag="VUR46_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456960.1"
                     /translation="MYNQKLIKMVKGLFVGFIAVLCIILGYSIAQVQQNLRQNSQVQE
                     EAKQKPEEKQQEQLSLTEQQVEEFLIAYYTKKDLEENRPRYKPFMTDSMYQETVQEEQ
                     KPVNQTYKGYVVDQAFESGSIYIDKQHKIALAQVQYTSTTLTEKDNRASKGLTGSTKA
                     TIRLTYVEKAGKLLINKIEPIVLTEARGQSVGTYADTSSSSSTPVSSTSTATPTSSEP
                     TTATSSNQ"
     gene            820..1059
                     /locus_tag="VUR46_001562"
     CDS             820..1059
                     /locus_tag="VUR46_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456961.1"
                     /translation="MNKKIEQLEGKLEKVRKDKEKAQRQKEEADKKIKNYINQEKDLE
                     AQLFVALSEESGLSYQEMKELILPAQSSNQGVNHV"
     gene            1052..1951
                     /locus_tag="VUR46_001563"
     CDS             1052..1951
                     /locus_tag="VUR46_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456962.1"
                     /translation="MYKIINQLTNQEETFEYRDDLLSRLEIINERMKSNKINGIYRLY
                     SLNSEGEILQEESLEIPFVGIIDQLLENFGMSAGKKKKGLLHFLEKHKEKNSSLGTPE
                     IQLQPEFQPEPDPELEDLTVTKEANMARQIIAELVSQKPRDEVREEVPLEDKMTYSSS
                     EWTTDHFSRLDENEEERVEPSQDMPTQEVVSIVEKSTQEEKIPLSVKEDKGNVETSFS
                     LSHVTSVNLPSEVIDSFEAQTVTYKQSIKHKIQSNEEFIKEANEEINECQNKINELRQ
                     QILAKEKQASQLKDLYFKIEEVS"
     gene            1953..2501
                     /locus_tag="VUR46_001564"
     CDS             1953..2501
                     /locus_tag="VUR46_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456963.1"
                     /translation="MEQEQVVAQLGRATLVTGEIILKGLFLVSSKAVEMYQARGENVL
                     FTGETDWNKFMATADTKEVQQLLNNEVNLEAVRKELGQYGIGFSFYTHPDGKTTLAFN
                     AKDKGVVEQAFKDVLEGITRDPRGFNERNLKNGKTTSFEEKLQHFKAVEQEKISSLQV
                     NIHTKEFVLSENIEPQIGGKMK"
     gene            2498..4333
                     /locus_tag="VUR46_001565"
     CDS             2498..4333
                     /locus_tag="VUR46_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET5456964.1"
                     /translation="MITEKKKRRLRPYLLLGIGLFYFFHWLFKLWLLAPDTDSVTDVF
                     GLGKLNWMSDHLNDKSWFDFQFTPTSLLIGMSGFLIAFLLYLRVTDTGTYRYGEEHGS
                     ARFATREELMRFRDEEPEKNMIFTQNSQMGLFNNRLSFENQINKNILVYGGTGDSKTR
                     SAVKPNILQGNSSFVTTDTKGILIHETGKSLVEKGYKMKIFDLITFLNSDGFNVFRYI
                     HNEMDIDRVAEAITESLNRNGHESDPFWPAANKLLMRSLIGYLYFDGQIDHYLPNLGQ
                     VTDMIRELRRNHPEAESPVELMFEDLERRSPGNYACRQWKLFNKNFDGQTRTSVYAIF
                     ATTFSVFDHEQLRKIIEKDTLEIEKWNIEKTAVFIHIPEVDPAYQFLSALLFSTVFDV
                     LIKTADAVILGEHPTKIKEDLLHLQVWADEFGQIGKIPNLPPIISVIRSREISIKMMV
                     QSQSQIEVLYGKENTKTIINNCGAILYLGSNDLDTLKYLSERSGKQTLNDQNYSESRG
                     RNASSSKQNSKIGRELLTPHEVATIGTTEALLFLSKQNVFRDQKFNLDTHPRAYLLSN
                     GSNDDNWYRYKRYLSDIDEWKAQVGEENVIYIGIKEVEEVPLKVS"
     gene            4674..5081
                     /locus_tag="VUR46_001566"
     CDS             4674..5081
                     /locus_tag="VUR46_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456965.1"
                     /translation="MKSTIKNYYEMWTKRHERRYREALGYYNQQSKEALLAELTELEI
                     KKERSSRSWKLLVGLVLTIIFSDDLKRLLAILFSPLTGVPTNKLHESVLPSISIALFI
                     VLLFLTILIYNFSYSLLLRRYLILKRYIEEHYT"
     gene            5097..5570
                     /locus_tag="VUR46_001567"
     CDS             5097..5570
                     /locus_tag="VUR46_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456966.1"
                     /translation="MYRDRFFEVLESPYTPYVAIELIYAIVVICFNLNLGNLNKQLTH
                     HFDIDKMINQKDVSIASNVMSYENNISWHFLFFGILLIIIGFIIPILFSIINKSSYKR
                     EEIKNAIWFIIAIVIVVNFFLIISISRALLSPIIIATLIVCAVGATLGSLAISNT"
     gene            5845..7194
                     /locus_tag="VUR46_001568"
     CDS             5845..7194
                     /locus_tag="VUR46_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456967.1"
                     /translation="MNTLPQKQFKRMKREVEEETARGIGYFEGILEHIPSYPLSEAVK
                     ELALSGWITPHTDVIDVQNMIVTESIKWMNYQDFKEVAPYLFSYPREQREKDLLVQPV
                     KISREYFEELKANAEELFHLKQDLLQVNNQLDAKIQELEMDQLPNGDQVIGVDLKAEE
                     VLLLRTPENAQVEEWEVRKDGLITDYRSNLSEYAQIVDALLEMENPEIDTILYEEVIN
                     YSKKTWPDSEPIQLPENIKELLNQEGKLDPSYYQIAQFETVKQAYIYGMISPSFQERF
                     PHYSDFIRNYVEDREQYEFFNYRTEAVSLAQEILVPRLGDINQILGTNNQELIVQEVV
                     GYSQGESWELAYLRDTKTEDRESVRFYLESEIGAWYKGSLTELAVIRFEDIDLEKGFN
                     GHQEAVYHIDENLLVQDKLKQAQLHFPDLKHFVEAEELEREQTQDIVAEKEEPEFSL"
     gene            7206..8468
                     /locus_tag="VUR46_001569"
                     /pseudo
     CDS             7206..8468
                     /locus_tag="VUR46_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            8472..9333
                     /locus_tag="VUR46_001570"
                     /pseudo
     CDS             8472..9333
                     /locus_tag="VUR46_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730738.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim"
     gene            10636..10944
                     /locus_tag="VUR46_001571"
     CDS             10636..10944
                     /locus_tag="VUR46_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456968.1"
                     /translation="MIEHLKQETFDLLMEIFFEDEATDSPKVNEVNQHISRKECLYIL
                     RRDMRIKTNYELEEVEMYPIVLKEIEGMSDERFEQLRDEILKMEMVDTMELILEDLKV
                     "
     gene            11166..11534
                     /gene="mobC"
                     /locus_tag="VUR46_001572"
     CDS             11166..11534
                     /gene="mobC"
                     /locus_tag="VUR46_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET5456969.1"
                     /translation="MENGEKRKRPVQKLIRLTEEENRFISTKVAESGMTNFNAFARIM
                     LIMGEVKILNFEELRELRKEINRIGVNINQVAKKVNEDDQASLTELSQILELQKYLKD
                     TVSQFIQKQENQTKEQERWL"
     gene            11525..13201
                     /locus_tag="VUR46_001573"
     CDS             11525..13201
                     /locus_tag="VUR46_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET5456970.1"
                     /translation="MVVTKVLQIKGVASLGRSTKYIEDEAKTVELTDTKSLNNALRYI
                     ENPSKTSFLEQDEQFEFPAVVKDGRVVKQLVSTYGITDASTATEEFLLTKKNAAQRAG
                     TKERSDIHNPNRVLAHHIIQSFSPEDDWTPQEIHEIGRKTILELTGGQHEFVIATHMD
                     KGHIHNHIIFNSTNSVTLKKFRWQKNTARSLFNISNKYSDLAGAKILKERLWTNRKTY
                     HAYRKKNSFRYEIKSRLDFLLKHSTSLEDFKIKARALNLEVDTSGKEIKYLLTDRDQT
                     RNVRDRTLSKKGNYSLEKISEKVVANEVTLSVDEIKSEYEKMVAEREDDFEMRITVEE
                     WQVMEETKNGIYLEMEFGLRNKGTILIPAHQIERAEDGSYEIFIRKNDFYYFVNPEHA
                     DKNRYMKGETVASQLSYDNGEMIIRKNPKISTLDQLVREYNYLSAHGVTEGQQFDELL
                     NRFEEELEEVDNLLDKLDQRLGELNKIQSAFLALESSDPQEVKLAIAIMKDLRVDPST
                     RKSEIDKLVKEATFERQTLYQRVEAITKDYKLHQDIEKNVEQRKEIETSL"
     gene            13277..14083
                     /locus_tag="VUR46_001574"
     CDS             13277..14083
                     /locus_tag="VUR46_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HET5456971.1"
                     /translation="MKIITFAAIKGGVGKTTLTFNYGEWLARKGHNVLFIDLDHQCNL
                     TQCYNIYESQNTIANAFKGGDVDIKHIKENISLIPGSVQLDTVERDLENSDKKNMLLY
                     LWLEDNYEKKKLGQFDYILIDCRPDFATATKNAVAVSHAIISPLTPSEFGYNAKFNLS
                     TRLEAFRKDVIDYRTRESYITAELYFLANMIRPNYGSSRELLEALGLEAKEKGTDNLL
                     GIVPAKELFNHSTIDKVSIADMKEKPDLYQKHKKFFMELEETFSRIYDTI"
     gene            14136..14357
                     /locus_tag="VUR46_001575"
     CDS             14136..14357
                     /locus_tag="VUR46_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456972.1"
                     /translation="MAFTPKEKEISQIIEATHQPEQLPDIDSFESFERKKQFQFTLKP
                     SNRKKLDQVAKAAGAKSASDYLDKLIEKL"
     gene            14422..15198
                     /locus_tag="VUR46_001576"
     CDS             14422..15198
                     /locus_tag="VUR46_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HET5456973.1"
                     /translation="MDLITRLLAEREGKVHGGIYDITQKRFAYNSNRIEGSRLTEEQT
                     SLIYETKTIANIDAKGIKIDDLVEMNNHFKCFDYILDTVNEPLTEDHIKTLHRVLKSG
                     TSSEHNPIAPVGRYKVLQNEVGKIATASVEQTEDEMLSLLIGYDLKKQKDLNYLTSFH
                     AQFERIHPFADGNGRIGRLLLYKQCLKEGLTPFIVDDINKATYYSALEAFQVHDNRQL
                     LFDYFQSEQLFYMNYLKNKGFEGAINDEKEGDFIKKSDKF"
     gene            15577..16898
                     /locus_tag="VUR46_001577"
                     /pseudo
     CDS             15577..16898
                     /locus_tag="VUR46_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397931.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISLre2 family transposase"
     misc_feature    17276..17407
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            17423..17953
                     /gene="infC"
                     /locus_tag="VUR46_001578"
     CDS             17423..17953
                     /gene="infC"
                     /locus_tag="VUR46_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET5456974.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            17986..18186
                     /gene="rpmI"
                     /locus_tag="VUR46_001579"
     CDS             17986..18186
                     /gene="rpmI"
                     /locus_tag="VUR46_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET5456975.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            18238..18597
                     /gene="rplT"
                     /locus_tag="VUR46_001580"
     CDS             18238..18597
                     /gene="rplT"
                     /locus_tag="VUR46_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET5456976.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            18655..19035
                     /locus_tag="VUR46_001581"
     CDS             18655..19035
                     /locus_tag="VUR46_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5456977.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLESLHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            19285..20085
                     /locus_tag="VUR46_001582"
     CDS             19285..20085
                     /locus_tag="VUR46_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET5456978.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKVNKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            20096..21034
                     /locus_tag="VUR46_001583"
     CDS             20096..21034
                     /locus_tag="VUR46_001583"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET5456979.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKTILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            21076..>21817
                     /gene="lytB"
                     /locus_tag="VUR46_001584"
     CDS             21076..>21817
                     /gene="lytB"
                     /locus_tag="VUR46_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET5456980.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAADEWVFDTHYQSWFYIKADANYAENEWIKQGDDYFYLKSGGY
                     MTKSEWVEDKGAFYYLDQDGKMKRNAWVGSSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDRQYQSWFY
                     IKENGNHADKEWIFENGHYYYLKSGGYMA"
BASE COUNT         7666 a         3386 c         4680 g         6085 t
ORIGIN      
        1 acgttaatag cgatggtagt ttcttagttt cagaaatgaa ctttggtggt ttatatgtat
       61 caagttggcg taccttgaaa ccacaatcag gtatctattt tgttacccct aaataagaaa
      121 ggaaaagaat gtataatcaa aagttaataa aaatggtaaa gggactcttt gtgggattca
      181 ttgccgtttt atgtattatc ctgggctatt ctattgctca agtacaacag aatttgagac
      241 agaatagtca agttcaggaa gaggcgaagc aaaaaccaga agagaaacaa caggaacaac
      301 tatctcttac tgaacagcag gtcgaggaat ttttaattgc ttactataca aaaaaggatt
      361 tagaagagaa tcgaccacgc tataagcctt ttatgacgga ttctatgtat caggaaactg
      421 ttcaagaaga acaaaagcca gtcaaccaga cctataaggg gtatgtggtt gaccaagctt
      481 ttgaatcagg atctatttac attgataaac aacataaaat tgctttagct caggttcaat
      541 atactagtac cactctaaca gagaaagata atagagcttc taaggggctt actggtagca
      601 ctaaggctac aattcggttg acctatgtag aaaaagcagg gaaactattg atcaataaaa
      661 tagagcctat cgtattgact gaagcgagag ggcaaagtgt aggaacctac gcagatacta
      721 gcagttcaag ttcaactcca gtttcttcta catcaacggc aacaccgaca tcttctgaac
      781 caacaaccgc aactagtagt aaccaataag gagaatggaa tgaataaaaa aatagaacaa
      841 cttgaaggta agcttgagaa agtgaggaaa gacaaggaaa aagcgcaacg acaaaaagaa
      901 gaagcagata aaaaaatcaa gaattacata aatcaagaaa aagatttgga agcgcagctt
      961 tttgttgctc tatcagaaga aagtggctta tcctatcagg aaatgaagga actaatcctt
     1021 ccagcacaat caagtaacca aggagtgaac catgtataaa attatcaatc aactgactaa
     1081 tcaagaggaa acatttgagt accgagatga cttgttatca aggctagaaa tcatcaatga
     1141 acgaatgaag agtaataaaa taaatggaat ctatcgactt tattctctca attctgaagg
     1201 tgaaatccta caagaagaaa gtcttgaaat accttttgtt ggcatcattg atcagttgtt
     1261 ggaaaatttt ggtatgagtg ctggaaagaa aaagaaaggt ttgcttcatt ttttagaaaa
     1321 acataaagaa aagaactcct cactaggaac accagaaatc caactccaac ctgaattcca
     1381 accagaacca gaccctgaac tagaagatct aacggtaacg aaagaggcga atatggctcg
     1441 tcaaataatt gctgagctag tttctcagaa gcctcgagat gaggttagag aggaagtgcc
     1501 tttggaagat aaaatgacct attcttctag tgaatggact acagatcatt tcagtagatt
     1561 agatgaaaat gaggaagaac gagtagaacc ttcacaagat atgcctacac aagaagtagt
     1621 ttctattgtt gaaaaatcaa cgcaggaaga gaaaatacct ctttctgtta aagaagataa
     1681 gggtaatgtt gagacttcct tctccctttc tcatgtgact tcagtaaatt taccttcaga
     1741 ggttattgat agctttgagg ctcagacggt tacttataag caatctatta aacataaaat
     1801 tcagtctaac gaagagttta ttaaggaagc aaacgaggaa attaatgagt gccaaaataa
     1861 aattaatgag ttgcgacaac agattcttgc caaagagaaa caagctagtc aactgaagga
     1921 tctttatttt aaaattgaag aggtgagcta aaatggaaca agaacaagtt gtagcccaat
     1981 taggacgggc aactcttgtg acaggagaaa tcatcttaaa aggactcttt ctggtgagct
     2041 ctaaggcagt tgaaatgtat caggccagag gggaaaatgt cctctttact ggtgagacag
     2101 actggaataa attcatggca acggcagata cgaaagaagt ccagcaatta ctaaataatg
     2161 aagtcaatct cgaggcagtt cgaaaagaac ttggccaata cgggattggc ttttcttttt
     2221 atacacaccc tgatggtaag acaactcttg ctttcaatgc aaaagataaa ggagttgtcg
     2281 aacaggcctt taaggatgtc ctagaaggca tcacaagaga tccgagagga ttcaatgagc
     2341 gaaatcttaa aaatgggaaa acgacttctt ttgaggagaa attgcaacat ttcaaagcag
     2401 tggaacaaga gaaaatttct tccctccagg taaacattca tactaaggaa tttgttcttt
     2461 cagaaaatat cgaaccacag attggaggaa aaatgaagtg attacagaaa agaagaaacg
     2521 aagacttaga ccgtatttgt tgttaggcat tggtctattc tatttctttc attggctctt
     2581 taaactatgg ctgttagcac cagataccga ttcagtaaca gatgtatttg gacttggaaa
     2641 gcttaattgg atgagcgacc atctaaacga taaatcttgg tttgattttc aattcacacc
     2701 aacttcttta ttgattggta tgagtgggtt tctgattgca tttctgctgt atttgagagt
     2761 aacggataca ggtacgtaca ggtatgggga ggaacatgga tcggctcgtt ttgcgacaag
     2821 agaagagttg atgagattcc gagacgaaga acctgaaaag aatatgattt tcacccaaaa
     2881 tagccagatg ggattattta ataaccgatt gagctttgaa aatcagatta ataaaaatat
     2941 tctggtatat ggaggtacag gggattcaaa gacacgtagt gctgtaaagc cgaatatttt
     3001 acaaggaaac tctagttttg taaccacaga taccaaaggg attttgattc atgaaacagg
     3061 gaaatcactt gtagaaaaag gttataagat gaaaattttt gatttgatta ctttcctgaa
     3121 ttcagatggt ttcaacgttt ttagatatat tcataatgaa atggatatag accgagtggc
     3181 agaggcaatt acagaatctc tcaatagaaa tggtcatgaa agtgatcctt tttggccagc
     3241 agccaataaa ctcctgatgc gctctctaat tggctatctt tattttgatg ggcagattga
     3301 tcactatctg cctaatttgg ggcaggttac agatatgatt cgagaattga gacggaatca
     3361 tccagaagcg gaaagtcctg ttgaattgat gtttgaagac ctggagagaa ggagcccagg
     3421 gaattatgcc tgcaggcagt ggaaactatt caataaaaac tttgatggcc aaacacggac
     3481 ttctgtttat gccatctttg cgacaacctt ctcagtgttt gaccatgagc aactaagaaa
     3541 gattattgaa aaggatacac tggagattga aaaatggaat attgagaaaa cagcagtttt
     3601 tattcatatt ccagaagtgg atccagctta tcagttctta tctgcccttc tttttagtac
     3661 cgtttttgat gtgctaataa aaacggcaga tgcagttata ttaggtgagc atccaacaaa
     3721 gatcaaggaa gatttattac atctacaagt gtgggcagat gagtttggtc agattgggaa
     3781 gattcctaat ttaccgccaa ttatctctgt tattcgttct cgagagattt ctatcaagat
     3841 gatggtgcaa tctcaaagtc agattgaagt attgtacggt aaagaaaata cgaagacgat
     3901 tatcaataac tgtggtgcta ttctttattt aggttccaat gacttagata cgcttaagta
     3961 tctatctgag cgatcaggga agcaaacttt gaatgatcag aattatagtg agagcagagg
     4021 aagaaatgcc agcagttcta agcagaactc aaaaattggt cgagaactgt tgacaccgca
     4081 tgaggttgcc actattggaa caacagaagc cctactcttt ctatccaaac aaaatgtctt
     4141 tcgagatcaa aaatttaacc tggatacgca tccaagagct tacctcttaa gtaatggctc
     4201 gaatgatgac aactggtatc gatacaagcg ctatctaagc gatattgatg agtggaaagc
     4261 ccaggttggg gaagaaaatg ttatttatat tgggattaag gaagttgagg aagttcctct
     4321 taaagtaagt taggaaagaa agggaatcta atggaatttt atgactctta ttgcgtttta
     4381 attgctataa attgggatca gtatgtgtgg ttgcattagg aaggcgaaaa aataacctgg
     4441 catgaaaatt tagctcatgc aggttttttt cgtgatttta atacagctaa aagggtagcg
     4501 gaaactcatt tattagaaac ttttggagcc ataggattct ataagattgt tggtttttct
     4561 acagatgaac ttgggtatat agaaaccaag aactagagag cacaatgtgt tttagtattt
     4621 tgtgatataa tgaatggaga ataagcgatg attgagagga gtgtaataat cctatgaaat
     4681 ctaccataaa aaattattat gaaatgtgga cgaaacggca tgaacgtcga tacagagaag
     4741 ccttgggtta ctataaccag cagtctaaag aggcattgtt agcagaattg acagagctag
     4801 agataaaaaa ggaaaggagt tctcgcagct ggaaattatt ggtaggtctt gtattaacca
     4861 ttattttttc agatgattta aaacggcttt tagcaatttt attttcacct ttaacaggtg
     4921 tacctaccaa taaattgcat gaaagtgtgt taccgagcat cagtattgca ctatttatag
     4981 ttttgttatt tttgactatt ttaatctata actttagcta ttcgttgcta ctgagacgct
     5041 atctcatttt aaaacgctat atagaagaac attatacttg aatataggag ataaatttgt
     5101 atagagatcg attttttgaa gtattagaaa gcccttatac gccttatgtg gcaatagaat
     5161 taatttatgc aatagttgtc atttgcttta atcttaatct gggaaattta aataagcaac
     5221 taacacacca ttttgatatt gataaaatga taaatcagaa agatgtgtca attgcgtcta
     5281 atgtcatgtc atatgaaaat aatatatcat ggcacttttt gttttttgga atcttgttaa
     5341 ttatcattgg ttttataata cctatattat tttcaattat aaataagtct agttataaga
     5401 gagaagaaat aaaaaatgcc atttggttta ttattgccat agtcatagtg gttaatttct
     5461 ttttaattat ttcaatatca agagctcttt tgagtccaat catcatagca actttaatag
     5521 tgtgtgcggt aggagcaaca ttgggatctc ttgcaatttc taatacctaa aagtacaagg
     5581 cagccgtaat ggctgttttt ttgatgaaag gagaatcaaa tggatttaga acaattgaag
     5641 caacgacgag atgagctgat taaagataat tgagtgggcg gatggcttaa ttaaagagaa
     5701 ggaagaaaaa ctatggtaag tgaaagtgag aacgattgca gcttctgagc tagcgagatc
     5761 ggcattggaa tctgctttac gttctgcagg tatcgtagat accttttacg gaccagataa
     5821 tagaaagaaa ggaaatgaaa tagaatgaat acactaccac aaaaacaatt taaacgaatg
     5881 aagcgtgaag ttgaggaaga aactgctcga gggattggtt attttgaggg gattttagaa
     5941 catatccctt cttaccccct atctgaagcc gtaaaagagt tggctttatc tggctggatc
     6001 actcctcata cagatgtcat cgatgtccag aatatgattg ttacagaatc tataaaatgg
     6061 atgaattacc aggacttcaa agaagttgct ccctacttgt tttcttaccc tcgagagcaa
     6121 cgagagaaag atttattggt tcaaccagta aaaatctcca gagagtactt tgaggaatta
     6181 aaggccaatg cagaagaatt atttcacttg aaacaagatt tgcttcaggt taataatcaa
     6241 ttagatgcta agatccagga attggagatg gatcagctcc ccaatggtga tcaagttatt
     6301 ggagtggatt taaaagctga ggaggtattg ttgctacgaa ctccagaaaa tgctcaggtt
     6361 gaggagtggg aggttcgtaa agatggcttg attactgatt atcgttccaa tctttcagaa
     6421 tatgctcaaa ttgtagatgc tttacttgaa atggagaatc cagagattga tactattctc
     6481 tatgaagaag taatcaacta ttctaagaaa acttggccag attcagaacc aattcaactt
     6541 ccagaaaata tcaaggaact attgaatcaa gagggcaagc ttgatccctc atattatcaa
     6601 atagctcagt ttgaaacagt aaaacaagct tatatttatg ggatgatttc acctagtttt
     6661 caggagcgtt tccctcatta ttcagatttc attaggaact atgtagaaga tagagaacaa
     6721 tatgagtttt tcaactatcg tacagaagcc gtctcattag ctcaggaaat tctagtacca
     6781 cgtttaggag atattaacca gattttagga acgaataacc aggagttaat cgttcaagag
     6841 gtcgttggtt attctcaagg tgaaagctgg gaactagctt atttacggga tacaaagacg
     6901 gaagatagag aatccgttcg attctatctt gaaagtgaga ttggagcttg gtataaggga
     6961 agtttgacag agttggctgt tatccgcttt gaggatattg atttagagaa aggatttaat
     7021 ggccatcaag aagcagtcta tcatatcgat gagaacttgt tagttcagga taagctaaaa
     7081 caagcccaac tccattttcc tgatttaaaa cattttgtag aagcggaaga acttgagaga
     7141 gaacagacac aagatatagt agcagaaaaa gaagagccag aattttcatt gtagggggat
     7201 aacagatggt gttaagcaaa gaagaagcca aaagattatc tattatttct gttgcagagc
     7261 aactaggcat ggagttaaag cgtacaggta gctatagcta taactgggta gaacatgatt
     7321 cctttgtaat agatgcaaag aaaaatgaat tttactggaa ctcaagaact gaatttggag
     7381 atgtcattca gttagttcaa accatacgag gtgtttctta caaggaggcg atgaattttt
     7441 tagaaactgg agaatttaag gcagtagatg tagaagctca gacggcctca aaagagcctt
     7501 ttagttatca cttggaaaga tatgagcgtc aggatttcag cgcctctaga cgctatttga
     7561 aggcacagag aggcctttca gatgatacga ttaacttctt tattagccaa ggcagtatag
     7621 cggaagcaat ccgaaaaaaa ggagactatt ttgagcctgt gattgtcttt aaatataaag
     7681 acaacacaag ctttttagct ggagcgagtc ttcagggaat agtagagaat cgagagcact
     7741 atcctgaacg tgggcgttta aaacaaatta tgagaaattc agacggacaa ctaggatttt
     7801 caattgatat cggaacacca aaacgtttga tctttgcgga agctccaatc gatctaatga
     7861 gctactatga gcttcataaa gatagtcttc aggatgtccg cttagtagct atggatggag
     7921 taaaagaagg aatcattagt agacggttta tggaattgta tgcagagata aatgataaat
     7981 cctatcaagt taatcagaat actgggaaag ctctagaagt agtcgctaga acaacgaact
     8041 attttaaaga tggtcagaat caagatatga ttaccttggc tgtagataat gatatggctg
     8101 gctataaatt tataactagt ctgcaggaaa aggggattcc agtacagatt gcgattccgc
     8161 ctatcgttca gagatatcag gagaaggaag attggaatga ctttctgaag ggagggaata
     8221 aatttcctaa ggagttagca cacgtttata cagtagacga aaagtcttgg tattaccagg
     8281 gcttttttga gaaggaacta gctcttgcaa aagcgcaaga gctaactgca gatgatgtaa
     8341 aagcctttgt gtcagatagg caattgacaa aggaagaagt ccgtcaagaa tatacaagga
     8401 ttgtcgatca agagaaagaa aggaaacata ctatgtcgga agtacatgaa gcaggggctg
     8461 agtatgaagt agaaaagcca gataatagtc gcttagcgca agctagacga aagctggagc
     8521 gactcaaagg agaagctgat gaggcaatta atgcggccta ttcccaccaa gcactaacaa
     8581 atgggcaacc catgaatgat aagcgaggaa gtgctagctt tatgcgtaag caagaacaaa
     8641 tagaaggtca agtcttctca aagctggatg agattaggca acaggaagag cgagtagagc
     8701 gcctggagca ccaacaacat ttgaaagaaa tggggttgaa tcgtcaggga agtggtctgg
     8761 atatgagtgt tcaaaatata cctcgaatcc gtgaagagtt agaaaaagct aaacgtgggg
     8821 agtcgttctt taccaaagct actctcaaac gctatcaaga agagttgact agagttgagg
     8881 ccatatctga acaaatgggt aaaacgagca ttcaaccagc aactcaagcc ttaattgatg
     8941 aggggctagt gaaccagtgg caaaaacaac caaatacgta ttttgtaaaa ggattacgaa
     9001 gagttgccct ggagttgact gaagaaggag agtttcaatt atcttcacaa atcaagtatc
     9061 atccgaaaac agatgaggaa agactgaagg tggatgaatt acttgccaaa caaaggcaag
     9121 aaaatgtagg attaacgccc tcgaatcagg aaaaatcaat ctcaccacaa ccagagccta
     9181 ttgaaaaaaa tcaaggcgaa gcagggtggt tagaaaaaaa ttgggacaat ctcacgtttt
     9241 cgatagaaaa taaaaaaaac agtcgtcatt gatccgacta gtatagatga gatggttgaa
     9301 aaattacaag tcaaagattc gcaagagaca ctagataatc gatacgaaaa aatttatcag
     9361 tataaccgaa aagatgagag ggatcgtgat ttggatggtg atggtatttc caattctgat
     9421 gagatgttgc agggaacaga tccatacaac ggtgcctcta accttcataa aaaacaggaa
     9481 gatagagaaa gaaggacaga tgttgaagcg gaaactggag ctattataac cgatgcaatt
     9541 gctactaaaa gttcagaaca aaccatttcc cagttagtcg caaataaaga tacaaaagct
     9601 ttagctgaac acttgaaaga aggaatgaag aactacttgg attcagaaca gtttaaatca
     9661 ttcttggata cgatgagtaa gtttcacaac tactcactca ataatattca tttgctgaag
     9721 atgcaaaatc ctaatgtttc ccaagttgct agtttcaata aatggaaaac agattttgac
     9781 agaacagtta aaaagggttc aaaagctctg aaaatctggg ttccgtatca agtgaaaact
     9841 aagatttttg ctaatcaaaa tgagttgagt ttttctccat ctgagaatga aacggaagag
     9901 aaggaagtca cagttactcg attcaagtta gggaatgtct ttgatgtatc tcaaacagaa
     9961 ggaaaagaat tgccaaaagc aattaatgaa ttgactggag atgttaaaga ttatgaagat
    10021 ttgtaccgag cagccaaagc tgtttcaatg gataatcagg ttcctatcag ttttgaagaa
    10081 attaaaagag agagcacaaa tggttattac tctccagatg aaaatcgaat tgttatttca
    10141 aaaggcttaa agggtcaaga acagatttta aaaaccattt ttcatgaaat ggctcatgca
    10201 gatttacata gaggaagcaa tgcccaatat ggggacgacc aatatcgtaa gcaagaatta
    10261 caagctgaaa gtgtcgctta tgtcgtggct aatcattttg gttttgatac gagtagctac
    10321 agttttggct atttggctat ttgggcaaaa gataaaaatg gttttgaaga tatggtagaa
    10381 caactgcagg ttgttcagaa ggaagcaaaa agtttgattg atcggatgga tgctaagtta
    10441 gaattagtga aaaataaaac tgtgacgaaa gataagtttg ctgataaact ccaacaggca
    10501 aaagaaaaat ctgagcagtt ggggaatcaa aaggcggagg ctgtaaagca ggtggaagaa
    10561 aaaaagtccc tgagcaaccc tcgataatgg aggcattagt ccgtaggaag aaaaacaaaa
    10621 aaggagaaac ggaagatgat tgaacatcta aaacaagaaa cttttgatct tttaatggag
    10681 atattttttg aggatgaggc tacagattcg ccaaaagtga atgaagtcaa tcagcacatt
    10741 tcacgtaagg aatgtcttta cattcttcgt agagatatgc gaattaaaac aaactatgag
    10801 ctagaagaag tagaaatgta tcccattgta cttaaagaaa ttgaagggat gagtgatgaa
    10861 cgatttgaac aactaagaga cgaaattctt aaaatggaga tggttgatac aatggagctt
    10921 atactggaag acttaaaagt ttagtcaaac ttttccctcg tgataggata acattcctgc
    10981 ttgcagggat taggggattg gggatttccc caaagattta aaaagtcaag aatagtcagg
    11041 gatgacaccc tgactaactt tgaccttttt aaaaacagca tttggatatc caagtgctaa
    11101 tcttgccaga agaaaagggg gcggaccccc tcagtcaaaa aatagcagaa tagaggtgta
    11161 aggttttgga aaatggagaa aaacgcaaaa gaccagttca aaaattaatc agattaactg
    11221 aggaagaaaa tcggttcatt tcaacaaagg ttgcagaatc tggaatgaca aattttaatg
    11281 cttttgcccg aattatgttg attatgggcg aggtcaaaat tttaaatttt gaagaattga
    11341 gagaattgcg taaggaaata aatcggatag gcgtcaatat taatcaggtc gcaaaaaagg
    11401 taaacgaaga tgaccaggct agcctaactg aactgagtca gattcttgaa ttgcagaaat
    11461 atttgaaaga tacagttagc caatttatcc aaaaacagga aaatcaaaca aaggaacaag
    11521 agcgatggtt gtaacaaagg ttcttcaaat aaagggtgta gcttctttag gacgatctac
    11581 aaaatatatt gaggatgaag ctaagacggt cgagctgact gatacgaaaa gtttaaataa
    11641 tgctttacgc tatatcgaga atccatctaa aacgagtttt ttagaacaag atgaacagtt
    11701 tgaatttcca gcagtggtta aagatggccg agtagtcaag caactggtat ctacttatgg
    11761 aattacagac gctagcacag cgacagaaga atttcttttg accaaaaaga atgctgctca
    11821 gcgagcaggg acaaaagaac gatctgacat tcacaatccg aatcgggttt tggctcacca
    11881 catcatccaa tcattttctc ctgaagatga ttggactcca caagaaattc atgagattgg
    11941 tcgaaaaaca attttagaat taactggtgg acaacatgaa tttgtcatag cgactcacat
    12001 ggataagggg cacattcaca atcacatcat tttcaattcc actaattctg ttacattaaa
    12061 aaagtttcgt tggcagaaaa atactgctag aagcttattt aatatttcaa acaagtattc
    12121 tgatttggct ggagctaaaa ttctcaagga gagattatgg actaatcgaa aaacctatca
    12181 tgcctatcgc aaaaaaaatt cttttcgcta tgaaattaaa tcacgcttag attttctttt
    12241 gaaacattca acctctttag aggattttaa gattaaggca cgagctttaa atcttgaagt
    12301 tgatacttca gggaaggaaa taaaatatct cctgactgat cgggatcaaa caagaaatgt
    12361 gagggatcgt acactgtcca aaaaaggaaa ttattcttta gagaaaattt ctgagaaagt
    12421 ggttgctaac gaagtaacct tatctgttga tgaaataaaa tctgaatatg aaaagatggt
    12481 ggcagaacga gaagatgatt ttgaaatgag aatcacagtt gaagaatggc aggtgatgga
    12541 agaaacgaaa aatggaatct atcttgaaat ggaatttggg cttagaaata agggaaccat
    12601 tcttattcca gctcaccaga ttgaaagagc agaagatggc tcttatgaaa tttttatcag
    12661 aaaaaatgac ttctactatt ttgttaatcc tgaacatgct gataagaatc gttatatgaa
    12721 gggagaaaca gtcgcttccc agttatcgta tgataatgga gaaatgatta tccgaaaaaa
    12781 tcctaaaatc tcaactttgg atcagcttgt tcgtgaatat aactatctat ccgctcatgg
    12841 agtgacagaa ggacagcaat ttgatgaatt gctaaatcgt tttgaagagg aactagaaga
    12901 agtagataac ttacttgata aactagatca acgcttgggt gagcttaata aaattcagtc
    12961 tgcatttctt gcattggaat caagtgatcc tcaggaagtg aaactagcta ttgctattat
    13021 gaaagacttg agagtagatc ctagcactcg caaatctgag attgataaac ttgttaaaga
    13081 ggcaaccttt gagcgccaga ctttgtatca acgggtagaa gcaattacaa aagattataa
    13141 gctacatcaa gacattgaga aaaatgtgga gcagcgtaag gagatagaaa cttcattgta
    13201 aaaaataagt ataaatatat ttacaaatat aattataatg gtataataga agtatagaaa
    13261 aggatggaga aatagaatga agattatcac atttgctgct attaaaggcg gtgttggaaa
    13321 aacaactttg acatttaatt atggagaatg gttggctagg aaagggcata acgttctctt
    13381 tatagattta gaccatcaat gtaatttgac tcaatgctac aatatttacg aaagtcagaa
    13441 tacaattgcg aatgctttca aaggaggcga tgtggatatt aagcacatca aggaaaatat
    13501 cagtctaata ccaggttcgg ttcagttgga tacagtggag cgagatttag agaacagcga
    13561 taagaaaaat atgctccttt atctttggtt agaagataac tacgaaaaga agaagttggg
    13621 tcagtttgac tatatcttga ttgattgtag accagacttt gcgacagcta caaaaaatgc
    13681 tgttgcggtt agtcacgcta ttattagtcc cttgactcct tcagagtttg gttataatgc
    13741 taaattcaat ctatcaactc ggttagaagc gttcagaaag gatgtaatcg attatcgtac
    13801 cagagagtcc tacattactg ctgagttata ttttctagca aatatgattc gaccaaacta
    13861 tggatcatca agagaattat tggaagccct tggacttgaa gccaaagaaa agggaacaga
    13921 caaccttcta gggattgtac cagcaaaaga gttattcaat cattctacga ttgataaggt
    13981 ctctattgca gatatgaagg agaagcctga tctctatcaa aaacataaaa agttttttat
    14041 ggagctagag gagacttttt caagaattta tgatacaata taattatatt tgtaaacaca
    14101 aatacaatta taaatataat tagaaggaga ttatgatggc atttacaccg aaagaaaaag
    14161 aaatttcaca gattattgaa gcaactcatc aacctgaaca gcttccagat atagatagtt
    14221 ttgaaagttt tgaacgtaag aagcaattcc agtttacttt gaagccaagt aatcggaaaa
    14281 agttagatca agttgcaaaa gcagctggtg caaagtctgc atcagattat cttgataaat
    14341 taatcgagaa actatagtta tggatatatt tataactata aacatatcca taactacaac
    14401 tgcttactac aaggagaaat aatggattta attacaaggc tcttagcaga gagagaagga
    14461 aaagtacacg gtggtattta tgatattaca cagaaacgct ttgcttataa ttctaaccga
    14521 attgaaggaa gtcgtctgac agaagagcag actagcttaa tttatgagac aaagacaatc
    14581 gcaaatattg atgcaaaagg aatcaaaatt gatgatttgg tagaaatgaa taatcatttt
    14641 aaatgttttg attatatctt agataccgtt aacgagccac tgacagagga ccatattaaa
    14701 acactgcatc gtgttctaaa aagtggaaca agttctgagc ataacccgat agctccagtt
    14761 ggtcgttata aagtattgca aaatgaggta ggaaaaattg cgacagcttc tgttgaacag
    14821 actgaagatg agatgctttc tttactgatt ggctatgatt tgaaaaaaca aaaagatttg
    14881 aattacttaa caagctttca tgcacaattt gaaaggattc atcctttcgc agatggtaat
    14941 ggtcgaatag gacgattgct tttgtataaa caatgcttaa aagaagggct tacccccttt
    15001 attgtggatg atattaataa ggcgacttat tattcagcgc ttgaagcctt tcaggttcat
    15061 gataacagac agctattatt tgattatttc caatctgagc aactttttta tatgaattat
    15121 cttaaaaata aaggatttga aggagctatc aatgatgaga aagagggaga cttcataaaa
    15181 aagtcagata aattctaaga aaaggtgcaa cagtttaagc taagaggaga aagtcatcac
    15241 ttaaaaaagt tattataatt atatttacaa atataaacat aattataaag tctgttgttt
    15301 tttgttgtaa aataccttct attggttgcg agataataat cttgacaacc gtactgagcc
    15361 tggttcttat atcaggcttt tattttacct tgaaatagaa acagttgaac ttctgatact
    15421 caactaaatc actttagtat ctttcaataa taaatagggc gttgatttta atttaaagaa
    15481 acagcctaat ttattcttgg aacaaaaata aatttgatga cttgttttaa aaatcataca
    15541 attttcataa gaattgaaag ggaaatgaaa aattgtatga aacaatttga tgaattgaga
    15601 tttagtagcc aggaacaaga aaagacaaaa caacattttt tacagcatat tgaacagtat
    15661 gatgagtcga taagctccag tatgagatca aaaggctatc gttgtaaaaa tcaagctgaa
    15721 cgtaccgtag cttttacatt tggagaagtg accttttcta gaaaacgttg gtataagaat
    15781 ggtgaatgta gaataccagt tgatgaaatg ttaggattag aaaagaatgt acgtcattca
    15841 caggaactat tgtatcaagc tgcggttcta gctacaaaac taccctatcg tcaggtagga
    15901 gagacaattg agatggttta taatgtaact gtcactaaag ataccgtcaa taaggttgtt
    15961 aaattagcca atcaattact agaagaaaag gatgattatc gattttttaa agaagagaag
    16021 aagattgaaa aattaaagca gatatcatct acatagaggg agatggtgta tatgtgaaaa
    16081 catctgaaga tggttctgaa aaaaagaata tggatttatc acattttgta gttcatacag
    16141 gttctaaaca gattggccca aatcgttttg agctagaaaa taaaaaagag cttatccgat
    16201 tggataagcg ctcagctcgt agagaattgt tggatttatt ggaaaatgaa tatgaaatta
    16261 caaatgggac aatactagtt actaattctg actgtggcaa gggttataca ccacatgtat
    16321 ttactgaaat cgctaaatca tttaatgtta agaggcatga gcatttttgg gacgaatatc
    16381 acttgaataa agaaattaaa gaatttacaa agtcttatcc gagagaattg agagaagact
    16441 tatttcaagc tattaaagag catgataaga aattattaag gcgtacacta gatactatag
    16501 aatcattggt tagtagtgaa gagggagagg aaaaatttga atattattcg agtaggttaa
    16561 tgaggaattt tcagtatacg aaaccagcgg aaatgagggg acttccaaag gcaggtattg
    16621 ggattatgga gagccagcat agaaaaataa cgtatagaat gaagcataga gggatgtatt
    16681 ggacaagtga aggtgggata gccgtagcga atatgatatt gttagagcgt gaaggaaaat
    16741 taagagattt attttttgga gaatggaagg aggactatga tgagtatacg tcattggatc
    16801 atatcagtgc ggatagtgtt cgacctaaaa atgactctaa agactacaaa cttccccgtt
    16861 tacataaaaa tatagaaaag atatttaaga tgaaataatt taagtgctaa tttcaacgaa
    16921 aacacaaata taaataagca aaaatttcta gtgagatttg ggcttttttg gcgtggaata
    16981 attgacattt atcctgattt tggtataata gagatataaa aaacaacgaa aaaaggagtt
    17041 ggaaatgagc ctccaactcc gcagagtaac acaacccaaa cttgtattac tcaatcaact
    17101 aaaatgatag cataagaaaa aatcattgtc aagggctgag catacaaaaa tgtttagccc
    17161 tttcgtgtat ttgcatttat ttatatggaa atctgggatt tctcaaaaat cacgacacat
    17221 acaaaataac tttttatctt gacaagagct agaaaacttg gtatcatata aaagttgaga
    17281 aaagcagaag tgagagcttc tcgccttgtg acattaagtt gcctggccct acggatgaaa
    17341 agtttctaag aaacgctatc ataacgtgcg ggcttgtata tttacaagtc cgctattgtt
    17401 tttctctaat aaaacaaaag aggtgaaaac catagcaaag caagacttat tcatcaatga
    17461 tgagattcgt gtacgtgaag ttcgcttgat tggtcttgaa ggagaacagc taggtatcaa
    17521 gccactcagt gaagcgcaag ctttggctga taacgctaat gttgacctag tattgattca
    17581 accccaagcc aaaccgcctg ttgcaaaaat tatggactac ggtaagttca aatttgagta
    17641 ccagaagaag caaaaagaac aacgtaaaaa acaaagcgtt gttactgtga aagaagttcg
    17701 tctaagtcca acaattgaca agggtgactt tgatacaaaa cttcgtaatg cacgtaagtt
    17761 ccttgaaaaa ggaaataaag ttaaggtatc tattcgcttt aagggtcgta tgattaccca
    17821 taaagagatt ggtgcaaaag ttttagccga gtttgctgaa gcaactcaag atattgccat
    17881 catcgaacaa cgtgctaaaa tggatggacg tcaaatgttc atgcaattgg cgccagcgac
    17941 tgacaaaaaa taattgtcag aaagttaaat aaaggagaaa aaatcatgcc aaaacaaaaa
    18001 acacaccgcg catcagctaa acgtttcaaa cgtacaggtt ctggtggact taaacgtttc
    18061 cgtgcttaca cttctcaccg tttccacgga aaaactaaga aacaacgtcg tcatcttcgt
    18121 aaagcatcta tggtgcattc aggagattac aaacgtatca aagcaatgct tactcgcttg
    18181 aaataatagc ttgactgtaa gtaaacaatt ctaggaaata tttggaggaa ataaaacatg
    18241 gcacgtgtta aaggtggcgt tgtatcacgc aaacgtcgta aacgtattct taaattagca
    18301 aaaggttact atggagctaa acacatcttg ttccgtactg caaaagaaca agtaatgaac
    18361 tcttactact atgcataccg tgaccgtcgt cagaaaaaac gtgacttccg caaattgtgg
    18421 atcactcgta tcaatgcggc agctcgtatg aacggacttt catactcaca attgatgcat
    18481 ggtttgaaat tggctgagat cgaagttaac cgtaaaatgc ttgctgactt ggctgttaac
    18541 gatgcagtag ctttcacagc tcttgcagat gcagctaaag caaaacttgg taaataacaa
    18601 ctgatgagac tggaacagga ttgtccagtc tttttaaaaa taaaggagaa agatatggct
    18661 tcaaaaatgc tacacacttg cttacgagta gaaaatcttg aaaaatcaat cgcattttat
    18721 caagatgctt ttggttttaa agaattgcgt cgcagagatt ttccagacca tgccttcacg
    18781 attgtctatc taggtcttga gggtgatgac tatgagttgg agttgactta taactacgat
    18841 cacggtccgt atgtggttgg tgatgggttt gcccatatcg ccctcagtac acctgatctt
    18901 gagtcacttc atcaagagca cagtgcaaaa ggctatgaag tgactgagcc aaatggtcta
    18961 ccaggaacta caccaaacta ttactttgtc aaagaccctg atggatacaa ggtcgaagtc
    19021 attcgtgaaa aataatttcg tgcaagttaa gtagaatatt cgttttctac ttgacttttt
    19081 ttagctgaaa gagtatacta ataaaaattc aacctttaag gggagtccag agagactcac
    19141 aaggtgtcag ataaaagaat agtgcaattt tctagaggag actttttgaa tgtgctctct
    19201 tgtgttgtac gattttaact gaggccttgc actagcaagg tcttttcttt atctggtccc
    19261 cttaaaattt aaggaggaaa agttatgaat cccacatgta agaagcgttt gggtgtcatt
    19321 cggttggaaa ccatgaaggt ggttgcacaa gaggaaatcg cgccagcaat ctttgaatta
    19381 gtcctagaag gagaaatggt tgaagccatg cgagcaggcc aatttcttca tctgcgtgta
    19441 ccggacgatg cccatctctt acgtcgtcct atttcaattt cgtctattga caaggtaaac
    19501 aagcagtgtc acctcattta tcggattgag ggagctggga ctgcaatttt ttcaacctta
    19561 agtcagggag acactcttga tgtgatgggg cctcagggaa atggttttga cttgtctgac
    19621 cttgatgagc agaatcaggt tctccttgtt ggtggtggga ttggtgttcc acccttgctt
    19681 gaggtggcca aggaattgca tggacgtgga gtgaaagtag tgacagtcct cggttttgct
    19741 aataaggatg ctgttatttt gaaaacggaa ttggctcagt atggtcaggt ctttgtaacg
    19801 acagatgatg gttcttatgg catcaaggga aatgtttccg ttgttatcaa tgatttagat
    19861 agtcagtttg atgctgttta ctcgtgtggg gctccaggaa tgatgaagta tatcaatcaa
    19921 acctttgatg atcacccaag agcctatcta tctctggaat ctcgtatggc ttgtgggatg
    19981 ggagcttgct atgcctgtgt tctaaaagta ccagaaagcg agacggtcag ccaacgcgtc
    20041 tgtgaagatg gtcctgtttt ccgcacagga acagttgtat tataaggaga aaattatgac
    20101 tacaaatcga ttacaagtgt ctctacctgg tttggatttg aaaaatccga ttattccagc
    20161 atcaggctgt tttggctttg gacaagagta tgccaagtac tatgatttag accttttagg
    20221 ttctattatg atcaaggcga caacccttga accacgtttt gggaatccaa ctccaagagt
    20281 ggcagagacg cctgctggta tgctcaatgc aattggcttg caaaatcctg gtttagaggt
    20341 tgttttggct gaaaagctac cttggctgga aagagaatat ccaaatcttc ctattattgc
    20401 caatgtagct ggtttttcaa aacaagagta tgcagctgtt tctcatggga tttccaaggc
    20461 aactaatgta aaagctatcg agctcaatat ttcttgtccc aatgttgacc actgtaatca
    20521 tggacttttg attggtcaag atccagattt ggcttatgat gtggtgaaag cagctgtgga
    20581 agcctcagaa gtgccagttt atgtcaaatt aaccccgagt gtgaccgata tcgttactgt
    20641 cgcaaaagct gcagaagatg cgggagcaag tggcttgacc atgatcaata ctctggttgg
    20701 aatgcgcttt gacctcaaaa ccagaaaaac aatcttggct aatggaacag gtggaatgtc
    20761 aggtccagca gtctttccag tagccctcaa actcatccgc caagtagccc aaacaacaga
    20821 cctgcctatc attggaatgg ggggagtgga ttcggctgaa gctgccctag aaatgtatct
    20881 ggctggggca tctgctatcg gagttggaac agctaacttt accaatcctt atgcctgccc
    20941 tgacatcatc gaaaatttac caaaagtcat ggataaatac ggtattagca gtctggaaga
    21001 actccgtcag gaagtaaaag agtctctgag gtaaactgca atcaatctgt tcttgatttt
    21061 ttattagttt gtaatatgaa tttaggagaa ttttggtaca ataaaataaa taagaacaga
    21121 ggaagaaggt taatgaagaa agtaagattt atttttttag ctctgctatt tttcttagct
    21181 agtccagagg gtgcaatggc tagtgatggt acttggcaag gaaaacagta tctgaaagaa
    21241 gatggcagtc aagcagccga tgagtgggtt tttgatactc attatcaatc ttggttctat
    21301 ataaaagcag atgctaacta tgctgaaaat gaatggataa agcaaggtga cgactatttt
    21361 tacctcaaat ctggtggcta tatgaccaaa tcagaatggg tagaagacaa gggagccttt
    21421 tattatcttg accaagatgg aaagatgaaa agaaatgctt gggtaggaag ttcctatgtt
    21481 ggtgcaacag gtgccaaagt aatagaagac tgggtctatg attctcaata cgatgcttgg
    21541 ttttatatca aagcagatgg acagcacgca gagaaagaat ggctccaaat taaagggaag
    21601 gactattatt tcaaatccgg tggttatcta ctgacaagtc agtggattaa tcaagcttat
    21661 gtgaatgcta gtggtgccaa agtacagcaa ggttggcttt ttgacagaca ataccaatct
    21721 tggttttaca tcaaagaaaa tggaaaccat gctgataaag aatggatttt cgagaatggt
    21781 cactattatt atctaaaatc cggtggctac atggcag
//
LOCUS       DAVDHZ010000034        21151 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000034 DAVDHZ010000000
VERSION     DAVDHZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21151
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.035"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            443..1804
                     /gene="trpE"
                     /locus_tag="VUR46_001585"
     CDS             443..1804
                     /gene="trpE"
                     /locus_tag="VUR46_001585"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET5456981.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFGNGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1801..2367
                     /locus_tag="VUR46_001586"
     CDS             1801..2367
                     /locus_tag="VUR46_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET5456982.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            2378..3382
                     /gene="trpD"
                     /locus_tag="VUR46_001587"
     CDS             2378..3382
                     /gene="trpD"
                     /locus_tag="VUR46_001587"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET5456983.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3379..4146
                     /gene="trpC"
                     /locus_tag="VUR46_001588"
     CDS             3379..4146
                     /gene="trpC"
                     /locus_tag="VUR46_001588"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET5456984.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLVEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4133..4732
                     /locus_tag="VUR46_001589"
     CDS             4133..4732
                     /locus_tag="VUR46_001589"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET5456985.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPSGVKKVGVFVSPSRVELLEVIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            4710..5933
                     /gene="trpB"
                     /locus_tag="VUR46_001590"
     CDS             4710..5933
                     /gene="trpB"
                     /locus_tag="VUR46_001590"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET5456986.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5926..6702
                     /locus_tag="VUR46_001591"
     CDS             5926..6702
                     /locus_tag="VUR46_001591"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET5456987.1"
                     /translation="MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVKPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(6674..6775)
                     /locus_tag="VUR46_001592"
                     /pseudo
     CDS             complement(6674..6775)
                     /locus_tag="VUR46_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            7209..7763
                     /locus_tag="VUR46_001593"
     CDS             7209..7763
                     /locus_tag="VUR46_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5456988.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIIYVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            7778..8929
                     /locus_tag="VUR46_001594"
     CDS             7778..8929
                     /locus_tag="VUR46_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET5456989.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKINNL"
     gene            complement(8981..9640)
                     /locus_tag="VUR46_001595"
     CDS             complement(8981..9640)
                     /locus_tag="VUR46_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET5456990.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNHFRCRYCKVRYPVWYALFELGLGLIFLLYSWGWLSLGQVILITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIAYSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASAMGILSFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            9710..10165
                     /locus_tag="VUR46_001596"
     CDS             9710..10165
                     /locus_tag="VUR46_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5456991.1"
                     /translation="MTIRFEEKVSTENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALQDLEGVFSIFDEQEFVELIHKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSL
                     AFENEDIDSISLNVLEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            10205..10477
                     /locus_tag="VUR46_001597"
                     /pseudo
     CDS             10205..10477
                     /locus_tag="VUR46_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10587..10790)
                     /locus_tag="VUR46_001598"
     CDS             complement(10587..10790)
                     /locus_tag="VUR46_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET5456992.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGVAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(10821..11429)
                     /locus_tag="VUR46_001599"
     CDS             complement(10821..11429)
                     /locus_tag="VUR46_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5456993.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEVVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(11460..11630)
                     /locus_tag="VUR46_001600"
     CDS             complement(11460..11630)
                     /locus_tag="VUR46_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET5456994.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(11642..12208)
                     /gene="amaP"
                     /locus_tag="VUR46_001601"
     CDS             complement(11642..12208)
                     /gene="amaP"
                     /locus_tag="VUR46_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET5456995.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIQLLSWRQNS
                     AVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVLDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIVDRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(12292..12489)
                     /locus_tag="VUR46_001602"
     CDS             complement(12292..12489)
                     /locus_tag="VUR46_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET5456996.1"
                     /translation="MAGKITKKGSSMGNIANVFAGLIGASAGQSLLGSWGPSIAGMAL
                     LPFIVGAAIMITVVSFFTGRK"
     gene            12905..14377
                     /locus_tag="VUR46_001603"
     CDS             12905..14377
                     /locus_tag="VUR46_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5456997.1"
                     /translation="MRDLLSKKSHRQLELLFEHKRWFHRSELAELLNCTERAVKDDLS
                     HVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFSEGCQAES
                     ICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQVIGNERDIRYFFAQYFSEKYY
                     FLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDK
                     DSFNDQSLNALMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDGSLFMK
                     CVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELSTEFILF
                     DQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVIN
                     LLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDI
                     IISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            14693..15949
                     /locus_tag="VUR46_001604"
     CDS             14693..15949
                     /locus_tag="VUR46_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5456998.1"
                     /translation="MEQLHFITKLLDIKDPNIQFMDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKTSMTDIAHQLAISTSTVIRKLNDFHFECKVRNLPEIMSWDEYA
                     FTKGKMSFIAQDFEKLNIITVLEGRTQAVIRDHFLKYDRAVRCQVKIITMDMFSPYYA
                     LAKQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLSRY"
     gene            complement(16014..16086)
                     /locus_tag="VUR46_001605"
     tRNA            complement(16014..16086)
                     /locus_tag="VUR46_001605"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16051..16053),aa:Lys,seq:ctt)
     gene            complement(16351..17622)
                     /locus_tag="VUR46_001606"
     CDS             complement(16351..17622)
                     /locus_tag="VUR46_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET5456999.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            17920..18135
                     /locus_tag="VUR46_001607"
     CDS             17920..18135
                     /locus_tag="VUR46_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457000.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDIPKEILD
                     LYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            18125..18373
                     /locus_tag="VUR46_001608"
     CDS             18125..18373
                     /locus_tag="VUR46_001608"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457001.1"
                     /translation="MKNRIIDVFEVVNRILVITVENPDFEDLRVNQFVKIGDKKYRVR
                     SGPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH"
     gene            18510..18689
                     /locus_tag="VUR46_001609"
     CDS             18510..18689
                     /locus_tag="VUR46_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET5457002.1"
                     /translation="MPMTQKEMVKLLTAHGWIKIRGGKGSHIKMEKQGERPITIPHGE
                     LNKYTERGIRKQAGL"
     gene            18726..19178
                     /locus_tag="VUR46_001610"
     CDS             18726..19178
                     /locus_tag="VUR46_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET5457003.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQT"
     gene            19469..19939
                     /locus_tag="VUR46_001611"
     CDS             19469..19939
                     /locus_tag="VUR46_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET5457004.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            19958..21025
                     /locus_tag="VUR46_001612"
     CDS             19958..21025
                     /locus_tag="VUR46_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET5457005.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVGITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKELAEGV"
BASE COUNT         6626 a         3777 c         4491 g         6257 t
ORIGIN      
        1 atacctacgg caaggcgacg ttgacgcggt ttgaagagat tttcgaagag tataaaggtg
       61 taccgagatg aacatctctt catcaatgtc tctggtcgtg gaggcaagga cctagctgcg
      121 attgcagact actagaagct aaaaaataat agatggaaaa attacagttc tttctctcac
      181 agagagcttg tggttgctga aaacaagcag agaaagctgt aaagttgggt tcatctgaaa
      241 cgagagaaga aaacatcatt ctcaagggag tgccctttat cgcacagcct gttacaggag
      301 atatctgaga caggaatgag agataggaga aatcctataa ttgaggtggc accgcgaatt
      361 tcgtcctcac gcaagttatt ttgcgtgggg atttttcata cagtcgctac gaactagaat
      421 tagaactgaa agggaaatta caatggaacg aatcattcat ggagatgtct tatcaccaat
      481 cttggcttat atgcgcttaa aggggcaaca caaggttatc ttagagagta ttccgagaga
      541 caaggaaaca gctcgttttt ctatcctagc ctataatcct gtttttgaga ttaagtttgg
      601 aaatggagtt ctttatcaaa atggtcaagt gattgatcgg gatcccttgg atttccttta
      661 tgaagtgatt cataagagtc agcaccattc agagctacct tttggtggtg gagccattgg
      721 ttttgtgggt tacgatatga tttcgcttta tgaagaaatt ggtcaaatcc ctgaggatac
      781 aattgggacg ccagacatgc atttctttgt ctatgagagc tatatagtct ttgaccacaa
      841 gaaggagaag atacatgtca tagaggatgc actttatagt gagcgcagtc aagaggcctt
      901 ggaaaaatcc ttgaaccaag tgcttgagga attacgcatt cctgctccaa atgaatttga
      961 agacttggat ttatcaccac ttgacttcaa accgcatatc gctccacata agtttgaggt
     1021 aatggtagaa actgctcgcg acttgattcg taatggtgat atgttccaat gtgtactcag
     1081 ccagcgtttc tcagcagaag ttactggaaa tccatttgac ttctacagaa atctccgcgt
     1141 gactaatcct tctaattacc tttatttcta tgattttggg gattatcaaa tcatcggagc
     1201 tagtccagaa agtttggttt ctgtcaaaaa tggcatcgtg acaaccaatc cgattgcagg
     1261 gacgcgacca agaggggcta cggatgaaga agacaaggcc ttggcgactg acctcctctc
     1321 tgatgagaag gaaacagcag aacatcgaat gttggtagac ttggggcgta acgatattgg
     1381 ccgcatctct gaaacggcca gtgtccaagt tactaagtat atggaggtgg agctcttccg
     1441 ctacgtcatg catttgacca gtgtggtcaa gggacgtttg cttgcagaac tcactgccat
     1501 ggatgccttg aaagcaacgc ttcctgctgg aaccgtttct ggagcaccaa aaattcgagc
     1561 tatgagacgc atctatgaac tggaaacgga aaaacggggc gtatatgcag gagcaatcgg
     1621 ctacttgtct gcgacgggtg atatggattt ggccattgcc atccgaacca tgattctcaa
     1681 aaatcaaaga gcctatgtgc aggctggggc agggattgtc tacgactcta tcgcccaaaa
     1741 cgaataccaa gaaaccatta acaaagcaaa atctatgact agaattggag aactaagacc
     1801 atgattttat tgattgacaa ctatgattct tttacctata acttggccca atacattggg
     1861 aattttgcag aagttcaggt tctgagaaat gatgattcca agctgtatga agaagctgaa
     1921 aaagcagatg gtctggtctt ttctcctggt cctggttggc cagttgatgc tggaaagatg
     1981 gaagacatga tttgtgattt tgcaggcaag aagccgattc tagggatttg tttgggtcac
     2041 caagccattg cagaagtctt tggtggtaag ctaggtttgg ctccaaaagt catgcatggg
     2101 aaacagagca atatcaactt tgaagcgcca tctgttttgt atcaaggtat tgaggatgga
     2161 cgtgcggtca tgcgttatca cagtattttg attgaggaaa tgccagaaga ctttgaagtg
     2221 acagctcgtt cgactgatga ccaagccatc atggggattc aacataaaaa cctaccgatt
     2281 tatggcttcc agtaccatcc agagagcatt ggaacgccag acggcttgtc ttctattcgg
     2341 aattttatcg agaaggttgt aaagtgagga aactaggatg aaagagatta ttgaaaaact
     2401 agcaaaattt gaaaatttat caggtgtgga aatgacggat gtcattgagc gtatcgtaac
     2461 tgggcgtgta actgaagcgc agattgcttc tctcctctta gctctcaaga tgaaggggga
     2521 aacacctgaa gaacgcacag ccattgccca agtcatgaga ggacatgccc agcatattcc
     2581 aactgagatt catgatgcca tggataactg tggtacaggt ggggacaagt ctttcagttt
     2641 taatatttcc acaactgcag cctttgtctt ggctggtggc ggtattcaca tggccaagca
     2701 tggtaaccgc tcgatttctt ctaaatctgg ttccgcagat gtcctcgaag ccttgggaat
     2761 caatcttgat ctcaaaccag ctgaactagg taaggtcttt gataaaactg gaatcgtctt
     2821 tctcttcgct aaaaatatgc acccagctat gaaatacatc atgccagctc gtttggaatt
     2881 gggaattcca acgattatga acttgactgg tccactgatt catccaatgg ctttagaaac
     2941 acagcttctt ggaattagtc gtccagaact cctagaaagt acagctcagg ttttgaaaaa
     3001 tatgggtcgc aaacgtgcca tcgtggttgc tggaccagaa gggttggatg aagctggctt
     3061 gaacggaaca accaagattg cacttcttga aaatggcgaa atcagcttgt caagctttac
     3121 tccagaggat ttgggaatgg aaggctatgc tatggaagat attcgtggtg ggaatgctca
     3181 ggaaaatgca gaaattttgc ttagcgttct gaaaaacgaa gcaagtccat tcttggaaac
     3241 gacagtcttg aatgctggtc ttggtttcta tgctaatggt aagattgata gcatcaagga
     3301 aggagttgcc ttggcccgtc aagtgattgc tagaggcaag gcccttgaaa aactcagact
     3361 gttacaggag taccaaaaat gagtcaggaa tttttagcac gaatcttaga gcagaaggcg
     3421 cgtgaggtgg agcagatgaa gctggagcaa atccagcctc tgcgccagac ctatcgcttg
     3481 gtagaatttt tgaagaatca tcaggaccgc ttgcaggtaa tcgctgaggt caagaaagct
     3541 agccctagtt tgggagatat caatctcgat gtggatattg tgcaacaggc ccagacttat
     3601 gaagaaaacg gagcagtgat gatttcggtg ttgacagatg aagttttctt taaaggacat
     3661 ttggattatc tacgggagat ttccagtcag gtagagattc cgacgctcaa caaggacttt
     3721 atcatcgatg aaaagcaaat catccgcgct cgcaatgcag gtgcgacagt catcttgctc
     3781 attgtggcag ccttggcaga agaacgtctt aaggaacttt acgactacgc gacagtgctt
     3841 ggtctggaag tcttggtgga aactcacaat ctagctgaac tagaagtggc tcacagactt
     3901 ggtgcccaga ttatcggggt caataaccgc aacttgacca cctttgaggt cgacttgcag
     3961 accagtgtag acttggctaa acatttcaaa gatgattgct tgtacatttc tgaatctgct
     4021 attttcacag ggcaggatgc ggaacgacta gccccatact ttaacggaat tttggtaggg
     4081 acagctctta tgcaggcaga aaatgtggcc cagagaatca aggagttgca gattgacaaa
     4141 ggttaagatt tgtggactat cgaccaaaga agcggtggaa acagccgttt cagcaggagc
     4201 cgactatatc ggttttgtct ttgcacctag taaaagacag gtgactttag aagaggcagc
     4261 tgagctggca aagcttattc cttcaggtgt gaaaaaggtt ggagtatttg tttcaccaag
     4321 tcgggtagaa ctgctagaag tcattgacaa agttggcttg gacttggttc aagttcacgg
     4381 tcaggtggca gatgatttat ttgagaattt gccttgtgcc agtattcagg ctgtgcaggt
     4441 agatggaaat gggcatgtcc ccaattctca ggcagattat ctactctttg atgcccctgt
     4501 ggcaggaagt ggtcagtcct ttgattgggg tcaactggat acgactggac tagcacagcc
     4561 cttctttatc gcaggtggcc ttaatgaaga taatgtagta aaagcaattc aacattttac
     4621 tccctatgca gtagatgtat cgagcggagt ggagacagat ggacaaaaag atcatgaaaa
     4681 gattagaaga tttatagaga gggtaaagca tggcatatca ggaaccaaat aaagatggat
     4741 tttacggaaa attcggcgga cgttttgtcc cagaaacatt gatgacagca gttttggagt
     4801 tggagaaggc ctaccgtgaa agtcaggcag acccaagttt ccaagaggaa ttaaaccaac
     4861 ttttgcgcca gtatgtggga cgtgaaactc ccctttacta cgcaaaaaac ttgacccagc
     4921 atatcggcgg agccaagatt tatctcaaac gggaagacct taaccataca ggagcccaca
     4981 agattaacaa tgccttagga caagtttggc ttgccaaacg catgggtaaa aagaaaatta
     5041 tcgcagaaac tggtgctggt cagcacggtg tggcaactgc aactgctgcg gccctcttta
     5101 acatggaatg taccatctac atgggtgagg aagatgtcaa acgccaagcc ctcaatgtct
     5161 tccgtatgga gcttttggga gctaaggtcg aggccgtgac agatggttcg cgcgtgctca
     5221 aggatgcggt caatgcagct cttcgttcat gggtggctaa tatagatgat acccactata
     5281 tccttggttc tgccttgggg cctcatccat ttccagaaat tgttcgtgac ttccaaagtg
     5341 tcattggtcg agaggctaaa caacagtacc gtgacttgac aggacaaaat ctgccagatg
     5401 ccctagtagc ctgtgttggt ggtgggtcga atgccatcgg tctcttccat ccctttgtag
     5461 aagatgagtc agtagccatg tatggagctg aagcggctgg acttggtgtg gatacggagc
     5521 accacgcagc taccttgacc aagggtcgtc caggtgtcct tcacggttcc ctcatggatg
     5581 tgctccaaga tgcccatggt caaattcttg aagccttctc tatctcagca ggtttggact
     5641 atcctggtat cggtccagag cattctcact accacgatat taaacgtgcc agctatgtcc
     5701 ctgtgacaga cgaagaagcc ttggaaggat tccaactctt gtctcgtgtg gaagggatta
     5761 tcccagcctt ggaatctagc catgctatcg cctttgcggt gaaattggcc aaagaacttg
     5821 gaccagaaaa gtctatgatt gtctgcctat caggtcgtgg ggacaaggat gtggttcaag
     5881 tcaaagaccg cttggaagca gatgcagcaa agaagggaga agctcatgcc taagacacta
     5941 acagaaaaat tgaatgctat aaaagcaact ggaaaaggaa tttttgttcc ctatatcatg
     6001 gctggtgacc acgagaaagg tttggacggt cttgctgaaa caattcactt tttagaagat
     6061 ttgggtgtct ctgctattga agtgggtatt cccttttcag accctgttgc agatggacct
     6121 gttatcgaag aagctggctt gcgcagttta gcccacggga cctctaccca ggctttagtt
     6181 gaaaccttga aaaccattga aacagagatt ccactggtca tcatgaccta cttcaacccc
     6241 ctctttcagt acggtgtgga gaactttgtc aaagatctgg ctgatacagc tgtgaagggc
     6301 ttgattatcc cagacttgcc tcatgaacat gccaactttg taaaaccatt tttggcagat
     6361 acagatatcg ccttgattcc tttagtaagc ttgaccacag gaattgagcg ccagaaagag
     6421 ttgattgaag gcgcggaggg attcgtctat gccgttgcca tcaatggggt gacagggaaa
     6481 tcaggcaatt accgtgcaga tttggacaag cacttggcgc aacttcatca agtggccgac
     6541 atcccagtct tgacaggttt tggtgtatct agtcaagccg atctggaacg cttcaatgcg
     6601 gtgtcagatg gtgttatcgt cggttcgaaa atagtaaaag ctctccacca aggagagccg
     6661 attcaggatt ttatcagaca agcagtagct taccaaaaat aatcaaacaa gtagcaagta
     6721 agaggaaagg cacgaaagga agtctttcct ttttcttttg caggagaaag gctagtttta
     6781 tagtgaattg aatctggaat attacactac ggttcctaaa atattttaag aaagtgattt
     6841 gaatttccca ataaatttgt tcagttttta attgatttta ctatagaaga tataattttc
     6901 taaattactc tgacacagaa ctttaagaaa aagctaatta ttgtagtaat ttctttaaga
     6961 aaatgatata attcattaaa aagtatttgg aggaggaaga attatgttga atcaggatct
     7021 ctttgattcg cttgaggcac aaaaaattgt agatactttg atgaaagggc aaaaagatta
     7081 tgtagatgaa cgtctagaaa aaagattatg tagatgaacg tctagaaaaa agagagacaa
     7141 tgatagtgtc gaatggttat gcatggacgc gacctaatca tattgatact gcatttgcat
     7201 cagcagattt gtttgagtat aaattacaat tagcaggaca gacttgggga tatttagaat
     7261 ttgaaacaaa tacagaaaaa tatgggaaag tattgttaat tataaagggt aagaagcgac
     7321 ttacgaacca atttcctttg gtacaaaaaa ataagagtgg ctacttattt gaatatgctc
     7381 aaatgaatac actttatctt aatcaacatt cttcctacaa aaatgatgaa gatagtcatt
     7441 cctttccaat tcagatggag ttagtttctg atgaaatgat tcaagaaatt gaacaagcta
     7501 ccaaaaattc gaatatcgaa aaatttatga ttttaactta tgaggcggac tcagaaaaca
     7561 atattatata tgtagatgtt gttatgcctg atgcacgaac tggtcagtta cacttgattc
     7621 aagatttgtc tgagtatatt caatcaagtt cgtaccattt cgaagaagct aaatatcaag
     7681 atattcctaa tttttcagaa ttatcggaaa cagaagattt tgaaattatt ccaagaatag
     7741 aaaaacaaga aggtcaaaag tagtaaggag tgtgtaaatg tttaatggtc gggtattgaa
     7801 agaattacgg ctgttaaatg gtttaagtag agcagaattg gctcagagaa ttaatttaac
     7861 ggaacaagcc atttggcagt ttgagtccaa cgaaacgaaa cctaaattat caaccaaaat
     7921 gcatttggcc aaccaatttc atgttgattt aacttatttt gaacaggaag aagagagcat
     7981 tcgatttgat tcttctgtaa ttgcctttag aaatgcagac ctagcaacac ggaaaacaat
     8041 agatattcaa actatgtatt tacataaggt agatagtttg attgattatt ttgaaagttt
     8101 tgtaattata cctaatatta caattcatga tctaagtaat gtagtgagtg aatcttatca
     8161 taagggagaa tccattgagg aattggctct ttatgccaga gaaaaattag gtatttcaaa
     8221 agataatcat gatttgcttt ataaattaga acgttcaggc atctatatcg tggaacgatt
     8281 aattaatggc caagctgatg cttatagcgc atggtcaaaa ttgggaagac cttatattgt
     8341 gttgggaacg aataaatcat ctgtacgtcg aaattttgac ttagctcatg agctaggaca
     8401 tattctttta cataaatata aagatatgaa tgaagatggc gatcgtttgg agcaagaagc
     8461 aaattatttt gcatcatgtt ttttattgcc aaaagaagag tttttagtca aatttgaaga
     8521 gagggttggc aagcgtgtca gcaatcctga tagttatatt ttattgaagt cggatttgaa
     8581 tgtttcgata caggctttag agtatcgagc ttttaagtta ggattattga ctccaaagca
     8641 acattcttac ttttatcgtc aaattgcgca aaaaggttac aaaatgattg aacctttgga
     8701 tgatcaaatt tttgttaaaa aaccaagcaa agtaaagagt attctggacg tcgttttgag
     8761 taatcatcta gtcagtctag cgactataat gtctaaacaa agtattcgtt tacagtttat
     8821 aagcgaaata ttttcagtcg aaatgaaatt ttttgatcag tatcaagaag atagaagaac
     8881 agatcgattt gataacatca tccctttgta caaaataaat aatttataat ttaactgtga
     8941 aataatttca tgaaggacat atggcagaaa ttggacttta tcaaacaagc agtagcttac
     9001 caaaaataat caaacaagta gcaagtaaga ggaaaggcac gaaaggaagt ctttcctttt
     9061 tcttttgcag gataaaggaa aggataccca tcgcagaagc aaactgaatc aagattagta
     9121 actccgttac gctaaagacg agagcacaag aagctaaaaa gaggaaatcc cctgcgccca
     9181 tgcggatatc gataaaatga gccaaaattc caagagcaag gaaggagacc atgaccagat
     9241 tccagccaga gtaagctatg aggattaggt ggaaagtcat ccagaccagt aagggatatt
     9301 cctgatggcg aaagtcgtag atacccaagg tcaaaccagc agtgattagg atgacttgtc
     9361 ccaaggagag ccatccccaa gagtaaagca gaaagatgag tcctaagcct agttcaaaga
     9421 gggcatacca gacgggatag cggaccttgc agtagcgaca gcgaaaatga ttaaaaacct
     9481 gcgatagaat cggaatcaaa tctaagggac gcaagcgagt ctgacaggaa tcgcagtgac
     9541 tggctgaact gataatggat tgctctggaa aacggtcaat gaccaaacca agaaaggagg
     9601 cgagaatgct cccgacgaga aaaaaataaa aatcaatcat acttatctat tcgtaaaaaa
     9661 tgggagaaat agtataatgg agaaacatag ataagatggt gaggaaaaga tgacaattcg
     9721 ttttgaagaa aaggtgagca cagaaaacgc tcaattcgta tgccagtggt ccaactccct
     9781 aggcaaatcc tttcaagaac aatggatggg accaaggatt ccttttctac tgacccttca
     9841 agccttgcaa gacttggaag gagtcttttc aatctttgat gaacaagagt ttgtggaact
     9901 tatccataaa atcaggctag aagacagcaa tcttcatatc gggagatttt ttatcaaccc
     9961 ccagaaacag gggcaaggct taggtagtca ggctttaagg aaatttgtta gtttggcctt
    10021 tgaaaatgaa gatatagata gtatttctct aaatgtctta gaggcaaatc aaagagctca
    10081 gaatctttac caaaaagaag gatttgaaat cgttcaaatg gttgaagcac ctgtacgaaa
    10141 atatatcatg aaaaagggga gatagaaagc aaacagcctt gaaatcaatg ttgactgcga
    10201 ttatgaacct gaatcagccc ctcaaaaggg actgtatatg aatgaacgtt accagtgttt
    10261 aaaaactaaa gaatatcagg cacttttatc ttccaagggt agacaaattt tcgctaaacg
    10321 taagattgat atgaaatctg tctttgggca gataaaggtt tgtttgggtt ataagagatg
    10381 tcatctgaga gggaagcgtc aagtgagaat tgacatggga ttcgtactca tggccaacaa
    10441 cctgctgaaa tataataaga gaaagaggca aaattaaaaa gctagagttc cgcaattggg
    10501 aatctctagc tttttgtttt ctgagaatca tcttgactca gactcttttg actaatgtta
    10561 ctaaaaagat aaagtaactt ttaaccttat ttatcgtcgc cactcaacat gtttttaaca
    10621 ccttctacag caccttctac agcgtctttg gcatcttcgg cgacttcttt tactttagaa
    10681 acaacttttt cagctactcc ttctttttcc attttttcat caccgatggc tttcccaaca
    10741 ccttctttaa tagaaccttt agcttgattt aatttttctt ctactgacat gataatttct
    10801 cctgttatat ttattttatc ttagtttaca cgagtgtttt cgtgagatac tacaccattt
    10861 gctgcacctt taacagcttc tacaccttcg ctaacttttt cttgaacagt tgagaaacca
    10921 gatccaagac cagatttagc tttttcgaat tgttctgaag tgaattctcc tgttgattca
    10981 gcaacgtcag atacgcgatc ttgaaggctt actgaatctg cttcatgctg ttctttagtt
    11041 ttgatgtcga caacgtttac gttgatttca acaacttcca agtcagtcat tttagcaact
    11101 tctgaagata cgatttctct gatttctgaa tataaagctg gaacattttt ttggtactca
    11161 acaataacgt ttaagtcaac tgcaacttgt gttttaccaa cttctacgtt aacaccactt
    11221 gttacgtcat cgctgttaac gattttttct ttaagatttg agaagaaacc accatcgatt
    11281 cccaaaagac ctgaaacgtt ttctagtgaa agaccaatga ttttttggat aactttatct
    11341 tcgtaagtaa gttccccttt gatttcgtga gctacaacag tagcatcttt cttttctacg
    11401 ttagtgtttg tgtttttttc gtttgacata tgaaactcct ttaattaaat tagtaatttt
    11461 tatttatcta tatagttttt ttcgatatat aatccagctg caactcccag tgctcctaaa
    11521 atcaatacaa atattgtttt gaagaagcca aaggagacaa tcaaacaagc aagaaatacg
    11581 cctatgagac cagcgataat tggatatcga tattgtttaa gccattccat tttttacttc
    11641 cttacttcac acgactaaca gtctttttgt tttgaggttt tggttggtaa ttttttactg
    11701 caacttcaag ttttacttga cgctcaatac caaaaaactg cttcaatcca ttagttattt
    11761 cattttgaat tatttggcat ctgtcaacga tgttgtctga aggaagaatt ttaccttcta
    11821 catgaacgaa acatttattt tttcgtaaat ttacatgaac agttgggttc ttgatcaatc
    11881 tatgatcaag aaccaaactt ctaacaaaac cttcgattgc cgaattcttt aattttaatg
    11941 tatcgttttt agtttcaagt tggatttcca agtaacgttt aggataaaac atcacaacta
    12001 aaatggataa taaaactaaa gttgatagaa ccactgtccc ccaaaagaca tatctagcaa
    12061 gatagaattc aactgcggag ttctgtctcc agctaagtag ttgaatacct agatcactaa
    12121 cttgatgata atctatcaaa acaggaagga aaattgtcaa gattaaaata cagaaaataa
    12181 tgaaacatat tttctttgct tttgacatat acaatccttt cgatttaaca tttaaactat
    12241 ttttcccgtc attgatttaa aaatagtttg ctaactttac tggcgaaaag ttcactttct
    12301 acctgtaaag aatgacacta cagtaatcat aatcgctgca cctacaataa atgggagcaa
    12361 agccattcca gcgattgatg gcccccaact acctaaaaga gattgtcctg cagatgcccc
    12421 gattaaacca gcgaatacat ttgcgatgtt tcccatagaa ctaccttttt tagtgatttt
    12481 acctgccaag agaccaataa gacctccagc aataattaat cacaacattg cctaccctcc
    12541 ttttttattt taatatcaaa aaatcaattt ctttgattac tactattata taactttaat
    12601 atagaaaagt caattatttt gattattatt attatataat tttaatatta aaaatcaaat
    12661 tctttgattg ttgctattat ataattttta aaattaaaaa tataatcttt agacttgaat
    12721 ttgattctgt attcacgccc tcaatagacg gtaaaataag aaaattgttt atatattgtc
    12781 tccgtagtgt tattatacga aataaaagat tttaggaaaa gtcgttatat catgctatac
    12841 ctattctttg tggtataatt gcaagaggtt taatccgata atttataaag agagaaagat
    12901 attcatgaga gatttattat ctaaaaaaag tcataggcaa ttagaattat tatttgaaca
    12961 taaacgttgg tttcatcgtt ctgaactagc agagttatta aattgtacag aacgtgcagt
    13021 caaagatgat ctatcccatg ttaaatctgc ttttcctgac ttgatttttc attcttctac
    13081 taatggtata cgcattatta ataccgatga tagtgatatt gaaatggttt accatcattt
    13141 ctttaaacat tcaactcatt tttcgatttt agaattcatc ttctttagtg aaggttgtca
    13201 agctgaaagt atttgtaaag aattttatat cagttcatct tcgctctatc gtattattag
    13261 ccaaatcaat aaagtgatta aaaggcaatt tcaatttgaa gtcagtctga cccctgttca
    13321 agtcattgga aatgagagag acattcgtta cttttttgca caatattttt cagaaaaata
    13381 ttatttccta gaatggccat ttgaaaattt ttcatcagag ccactatctc aattgttaga
    13441 attggtttat aaggaaacaa gctttccaat gaatttgtca acgcatagaa tgctaaagtt
    13501 gctcctagtt acgaacctat atagaataaa gtttggtcat tttatggaag tagataaaga
    13561 ttcttttaac gaccaaagtt tgaatgcttt gatgcaggca gaaggaatag aaggtgttgc
    13621 tcagagtttt gaatcagaat acaatatctc tttagatgaa gaagttgttt gccaattatt
    13681 tgtgtcttac tttcaaaaaa tgtttttcat agatggaagt ctctttatga aatgcgtaaa
    13741 aaaggatagt tatgttgaaa aatcttacca tctattgagt gattttattg atcagatttc
    13801 agtcaagtat cagattgaaa tggagaataa ggataatctg atttggcatc tgcataatac
    13861 cgcacatctg tatcgtcaag agttgtccac tgagtttatt ttatttgatc aaaaagggaa
    13921 tacaatcagg aactttcaaa atatttttcc aaaatttgtt tcagatgtaa aaaaagagct
    13981 ttctcactat ttagagactc ttgaggtttg ttctagttca atgatggtaa atcatctatc
    14041 ttataccttc atcactcata ccaaacattt ggtgattaat ttgctacaaa atcagcctaa
    14101 actaaaggtt ttggttatga gtaattttga tcagtatcat gcaaaattcg ttgcagagac
    14161 actttcttat tactgtagca ataattttga actagaagtt tggactgaat tagaattatc
    14221 aaaggaatct ttagaagatt caccttatga tatcattatt tctaatttta ttattcctcc
    14281 tattgaaaat aagagactca tctattcaaa taatataaac acggtctcac tcatatattt
    14341 gttaaatgcc atgatgttta ttcgattaga tgagtaacca aaaataacaa aaaaacgcta
    14401 tttcgcgttt gaactgtacc tcaaaagtta gacagaaaaa atctaatttt tggggtgttt
    14461 ttgttaagaa aagaccttca atcatttaag caaaatgtac atctagattt atagccttct
    14521 aaaactctta ctttttttgt agaagatacg aaaaaagcca tgaaaccagg ctctataata
    14581 tttgtagtgg gtaaatcccc tatggatatt atggagccta ttttagggta gaaaaaaagt
    14641 cccatatcat ctataatgaa aagcgacaaa ataactcatt agaaagaatc atatggaaca
    14701 attacatttt atcacaaaac tactcgatat caaagaccct aatatccaat ttatggatat
    14761 cattaataag gatacacaca aggaaatcat cgccaaactg gactacgacg ccccatcttg
    14821 ccctgagtgt ggaaaccaat tgaagaaata tgactttcaa aaaccttcta aaattcctta
    14881 tcttgaaacg actggtatgc ctactagaat cctacttaga aagcgtcgat tcaagtgcta
    14941 tcattgctcg aaaatgatgg tcgctgagac ttctatcgtc aagaaaaatc accaaattcc
    15001 tcgtattatc aaccaaaaga ttgcgcaaaa gttgattgaa aaaacttcta tgaccgatat
    15061 tgcccatcaa ctggccattt caacttcaac tgtcattcgc aagctcaatg acttccactt
    15121 tgagtgtaag gttagaaatc tgcctgagat tatgtcttgg gacgagtatg ccttcactaa
    15181 gggaaagatg agtttcattg ctcaggactt tgaaaagctc aatatcatca ctgttcttga
    15241 ggggagaacg caagctgtca ttcgagatca ctttcttaaa tatgatagag ccgtccgctg
    15301 tcaggtgaaa attattacca tggatatgtt tagcccttat tatgccttgg ctaaacagct
    15361 ttttccatgt gctaaaatcg ttctagatcg ctttcacatt gtgcaacatc ttagccgtgc
    15421 tatgagtcgt gtgcgtgtcc aaatcatgaa ccaattggat cgaaaatctc atgaatacaa
    15481 ggctatcaag cgctactgga aactcatcca gcaagatagt cgtaaactga gtgataaacg
    15541 attttatcgc cctacttttc gtatgcactt gaccaataaa gagattctag acaagctttt
    15601 gagctattca gaagacttga aacaccacta tcagctctat cagctcttgc tttttcactt
    15661 ccagaataag gaaccagaga aatttttcgg acttattgag gacaatctta agcaggttca
    15721 tcctattttt cagactgtct ttaaaacctt cctcaaagat aaagaaaaga ttgtcaacgc
    15781 ccttcaacta cactattcta acgccaaact ggaagcgacc aataatctca tcaaacttat
    15841 caagcgcaat gcctttggtt ttcggaactt tgaaaacttc aaaaaacgga ttttcatcgc
    15901 tctgaacatc aaaaaagaaa ggacgaaatt tgtcctttct agatattagc tgacttcaac
    15961 ccactacagt tgacaaagag cctgaaacca aggcttttct tgttgtatgt agatgccccc
    16021 tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca gctgagctaa
    16081 ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt gaacccgcgc
    16141 aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga cggcctacat
    16201 gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa cacttaagtg
    16261 tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttca aaaaaaatca
    16321 agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaacggt cgatagcttc
    16381 ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga aatagtgatg
    16441 attacgaatt ttttctggca gatagtcttg cttgacccaa tttccaggat agttgtgtgg
    16501 atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc catcacgcag
    16561 gtgtcgcgga ataggcaagt gccctgatgt tttgagatca gcaagtgcct tatccatagc
    16621 tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat tggcaatgag
    16681 aatgcgggct tctgggaacc caatcttctg tgcagcatcc agagcagtca cggtatgaat
    16741 ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca agcgacgagc
    16801 gagactaggc agatccccag cctcaatcaa gcgggcagca tagtggagac tggcatccac
    16861 atctgagcca cggatagact tttgcagggc agatagaaca tcatagtgac cgtctccatc
    16921 cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta aggtgatgtg
    16981 gcgaatgccc tcgtcattct caggggtaga gagaacagcc aagtccagtg agttaaaggc
    17041 agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct catctagttc
    17101 tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg cctctttgac
    17161 gtcttggtta gacagaggtt ccaactcaaa aatttgaaca cggctacgaa tggcaggagt
    17221 gacggaaaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc cactttccaa
    17281 gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt ctagcaatag
    17341 gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct ttttactatc
    17401 aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg cagaggcaat
    17461 actggttttg ccgattcccg gagggccata gagaatcatg gaggacaggc ggttggcttc
    17521 caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga tgacctggtc
    17581 gatggtttta gggcgcatac gaagcgcgag attgtctggc atagcagtcc tttctaacgt
    17641 ggatttgagt agaatgactc atctactata tcttactatg tccattctag cctattagtt
    17701 gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt ttactattta
    17761 atttaataag gagaggtatc agcatgagag atttgatttt ccttaaagct caaaatagga
    17821 tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgcta aatgtcattg
    17881 tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggaact accaagtcag
    17941 gaaattttga tttttacaaa acaaattcgt cattggattc ttagtgatca agttatttca
    18001 gggaaaagaa aacttttctt ccgggaagat attccaaaag agattttaga tttgtacgaa
    18061 aacattaaat ctaaacttga ttttgcttac caagaagttt attctaataa tgggttgaaa
    18121 aaatatgaaa aatagaataa ttgatgtttt tgaagtagta aatcgcatcc ttgtaataac
    18181 tgttgaaaat cctgatttcg aagacttgag agttaatcag tttgtaaaaa ttggagataa
    18241 aaagtataga gtacgcagtg gtcctatgat tcattcaact ccgcctcaat ctgtcttaga
    18301 tcgagatact tttacaattg actatacaga tgatgaattg ctcgataaag aagcagtttt
    18361 tactactcat tagaaaaata ggtatgaata aattggcttc ccttagaacc acatctaggg
    18421 gcttttatgt ataatagaat aataagtatc actcctttac aatacgtgta acacgtgtta
    18481 taatggtgtt gtcaggaggt aaaagcgcta tgcctatgac acaaaaagag atggttaaac
    18541 tccttacggc ccatggttgg ataaagatta gaggcggtaa aggttcccat attaaaatgg
    18601 aaaagcaagg ggaaagacct atcacaatcc ctcatggtga gctgaataag tacactgaaa
    18661 gagggataag aaagcaagct gggttgtaaa attcagcccc tgctttttga tatggaggta
    18721 gtgaaatgtt agttacgtat ccagctttat tttattatga cgacacagac ggaacagaag
    18781 cgacttattt tgtccatttc ccagattttg aatactcagc tacacaagga gaggggattt
    18841 ctgaggcttt ggctatgggg tcggagtggc tagggataac tgttgcagat ttgatagaga
    18901 gtgatggaga gttacctcag ccatcagata tcaatagctt gtctttaatt gataatgatc
    18961 cttttaaaga tgatgaagat ttcgtgtcaa cctatgacct tgataaatct tttatttcta
    19021 tggtatctgt tgatgtatca gaatacctag gaagtcagga acccattaaa aagactttaa
    19081 ccataccaaa atgggcagat aagttgggac gagaaatggg acttaacttt tctcagactt
    19141 tgacagacgc tattgcagat aagaaagttc aaacctaaga ttaagcgtgg tatcgtggta
    19201 atagtcaata aaaaagcacg tccacttgtg ctagttactc gcctattgat tttatagatt
    19261 tattagccct ttcgagggct ttttatattg atttttatga gaaatgaaga aatcagactt
    19321 ttaagaaaat cactgatacc aagggtttaa atgaggtaat atggtataat taggacataa
    19381 aataattttg tggtaagatg gtagtatcta ttttagcata tttccgagca atcggggcga
    19441 ttaaagagtc gcatagaaag aggacaaaat ggcaacatac ggatttttag atgttttaga
    19501 ggaagagttg gacaagaact ttccctttga ctttgagatt agctgggaca aacgcaacca
    19561 tgcggtagaa gtgagttttc tattggaagc gcaaaatgct gcaggtgtgg agatggtgga
    19621 tgaagacgga gaggtttcat cagatgacat tctttttgag gaagcggtcc ttttctacaa
    19681 tcctgccaag tcaacagtca atgaggaaga ctatttgact gttattcctt acctgcctaa
    19741 aaaaggattt tcccgtgaat ttttagctta ttttgcgctt ttccttaaag atactgctga
    19801 ggttgggcta gatgtcctca tggacttttt ggaagaccca gaagcagagg aatttatcat
    19861 ggaatggaac caagaagtct ttgaagaagg aaaagttggc ttggaagagg gagaatttta
    19921 tccttatcca agatactagg agttggttgg aggtgttatg aagaaaattg ggacttattt
    19981 ggtttatgtg ctagcttttg tctttattat gctagctttt gcttgtggaa caatcgcatt
    20041 tgcagagttg gggtattccg cagttttagc ctttactttt ggttatgcct tcgctcttct
    20101 aagcatgtat ttaatcttta ttcttcatga gctgggtcat gctttttgtg gctacttgac
    20161 aggctatcgg ctggtggctt ttggattagg acattttatt ttgaccaaaa agtcaggcag
    20221 gtttcatctt agtagaacag ccattctgaa aaatgttggt gctcaataca ttggtttaaa
    20281 agaggatgaa agcgatcaaa gaatcatcct gatgctttca ggaggcttga tggttcatct
    20341 cggcttgata ttattggcga tagtgtttgg atttttgaca agaagctggt attttgcagg
    20401 gacttggatt tttcttaatt tatctttctt cctaaataac attttaccag tcggcatcac
    20461 cgatggagca aaaatttggg aattactaca acaccctgaa aataccaaat acgcctacct
    20521 ggtattgaga cattctgctc aaactttgct ggctcctcaa gaatatgatt tgaaagactt
    20581 tgttcaagca gttcctgagg atgcacgagg gagttttgcg gatggtgtat taggtatgca
    20641 aggtgaagtt tccattttgg aagggaagga agaagtagct aaacagcagt ttcaagcatt
    20701 acttgagagg acaactactc cgatgatgca gacagttgcc caactatccc tgcttcatat
    20761 cgctttgttg gaaggagatt ttgagcaagc ggagcaatat gctagtattc gacaggtcaa
    20821 atcgtttctg tctctcaaac tgtccaatct tcaagtgata caagcctggt atcaattaaa
    20881 ggtgaagaaa gatgtagatc gaactcgtaa ggctctcaag attgctagac agaaaatgga
    20941 tagtagtcga atgttgaggg atgagaaaag atattatgaa aactggttag ccgagctgga
    21001 aaaggaatta gccgaaggag tctaatatgg aaatagagat ttctgatttc acaggttgca
    21061 agattgcttt gttttgtggg gataagcttt tgactatctt acgcgatgat aaggcaagca
    21121 ttccctgggc caatatgtgg gaactgccag g
//
LOCUS       DAVDHZ010000035        20855 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000035 DAVDHZ010000000
VERSION     DAVDHZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.036"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..154)
                     /locus_tag="VUR46_001613"
     CDS             complement(<1..154)
                     /locus_tag="VUR46_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET5457006.1"
                     /translation="MKSIKEEIQTIKTLLKDSRTAKYHKRLQIVLFRLMGKSYKEIIE
                     LLDCNQT"
     gene            complement(673..2400)
                     /gene="ezrA"
                     /locus_tag="VUR46_001614"
     CDS             complement(673..2400)
                     /gene="ezrA"
                     /locus_tag="VUR46_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET5457007.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVEEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2482..4428)
                     /gene="gyrB"
                     /locus_tag="VUR46_001615"
     CDS             complement(2482..4428)
                     /gene="gyrB"
                     /locus_tag="VUR46_001615"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET5457008.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSESRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4443..5006)
                     /locus_tag="VUR46_001616"
     CDS             complement(4443..5006)
                     /locus_tag="VUR46_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5457009.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNKGGHHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5091..5645)
                     /locus_tag="VUR46_001617"
     CDS             complement(5091..5645)
                     /locus_tag="VUR46_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET5457010.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLSAICAA
                     PIALNQAEILKNKRYTCYDGVQEQIFDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5656..6879)
                     /locus_tag="VUR46_001618"
     CDS             complement(5656..6879)
                     /locus_tag="VUR46_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET5457011.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6916..9366)
                     /locus_tag="VUR46_001619"
     CDS             complement(6916..9366)
                     /locus_tag="VUR46_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET5457012.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDYYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEEIYRNQSILTSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPHNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9566..10495)
                     /locus_tag="VUR46_001620"
     CDS             complement(9566..10495)
                     /locus_tag="VUR46_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET5457013.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10635..10922
                     /locus_tag="VUR46_001621"
     CDS             10635..10922
                     /locus_tag="VUR46_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET5457014.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10956..12290)
                     /gene="ciaH"
                     /locus_tag="VUR46_001622"
     CDS             complement(10956..12290)
                     /gene="ciaH"
                     /locus_tag="VUR46_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET5457015.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12280..12954)
                     /gene="ciaR"
                     /locus_tag="VUR46_001623"
     CDS             complement(12280..12954)
                     /gene="ciaR"
                     /locus_tag="VUR46_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET5457016.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13063..15609)
                     /locus_tag="VUR46_001624"
     CDS             complement(13063..15609)
                     /locus_tag="VUR46_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET5457017.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEITARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15732..16172)
                     /locus_tag="VUR46_001625"
     CDS             complement(15732..16172)
                     /locus_tag="VUR46_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET5457018.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16147..17016)
                     /locus_tag="VUR46_001626"
     CDS             complement(16147..17016)
                     /locus_tag="VUR46_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET5457019.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTKVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16994..17494)
                     /locus_tag="VUR46_001627"
     CDS             complement(16994..17494)
                     /locus_tag="VUR46_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5457020.1"
                     /translation="MEIKKHFGVYAVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17505..18203)
                     /locus_tag="VUR46_001628"
     CDS             complement(17505..18203)
                     /locus_tag="VUR46_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET5457021.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18196..18462)
                     /locus_tag="VUR46_001629"
     CDS             complement(18196..18462)
                     /locus_tag="VUR46_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET5457022.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(18530..19456)
                     /locus_tag="VUR46_001630"
     CDS             complement(18530..19456)
                     /locus_tag="VUR46_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET5457023.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19531..20346)
                     /locus_tag="VUR46_001631"
     CDS             complement(19531..20346)
                     /locus_tag="VUR46_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457024.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWENFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILILAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRWCLVQDSPKMKIGTYI
                     VVGILVLLVVMGYVGIGSFVQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20350..20670)
                     /locus_tag="VUR46_001632"
     CDS             complement(20350..20670)
                     /locus_tag="VUR46_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET5457025.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6282 a         4553 c         3699 g         6321 t
ORIGIN      
        1 ttgtttgatt acagtctaaa agttctataa tctctttata agatttgccc atcagacgaa
       61 atagaacgat ttgaaggcgt ttatgatatt tagctgtacg agagtctttt aaaagtgttt
      121 tgatggtttg gatttcttct ttaattgatt tcatattact ataatgtctt ccaaacgagg
      181 aaactctcgt aaacaaagag gttttagagg cctatttacc gtggactaaa gttgtacaag
      241 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttctct aatctgaaga
      301 tttttcaata gacttcgtta ttggacggtt accaagttac tcaaagtaca gatttgaagc
      361 tgcagataag actgacgaaa tcactttaat actaaatgaa aatcaaaaag caaactaaga
      421 agctagcctc aggctgctca aagtacagct ttgaggttgc agataaaact gacgaagtca
      481 gtaacatacg cacggtaagg cgacgctgac gtgatttgaa gagattttcg aagagtataa
      541 aacactgttt tgaggtggtg gataaatcgg ctgggcaaaa actcaatctc aggagaaaat
      601 gaagtaaatc tccccacaac tatagaaaaa gatttgattc tgctcctcac acaataaaat
      661 ctttttcttt tattaaaaac gaatcgtttc acgtgttttc tcatatgagg taacaaagcg
      721 attggttaca ccaggctctt ccacttccaa tgcttgagaa atcttgtcaa atgaagcgtg
      781 ataatcaaat tctttttcaa aaatatctaa agcttcgtta aatgcttctt gaatgcgttc
      841 atcaaatgag cgatagcggt tagaatattg caagagttgc tctgtcaaag ttgcatattg
      901 tacaatatta taagtttccg tttctaaagc ttccatatca ttcgttgcaa tttcaagaac
      961 tcgggtaaca gattcaatgt taatcatttt ttgttctaac tcaaccatta aatcctcggt
     1021 attattgctt gccgtaaaga ataacttcaa gaaagtttgt ggaatacctg gcagattgcg
     1081 tttttccatg tatcgcttga tagtatggag acgattgaca taaacattgg ccttttgacg
     1141 tgcattaata tcatctttct caatttgtgt caggcgctca ctaactgaaa tttgctcatc
     1201 ttcaatatct tttagttgag tttgtaaatc ctcaagattt tcttcaagaa ctgaataagc
     1261 ttgggttggt tcttcttgat ttgaagttac ctcaacaatg gctgcctcaa aactctctaa
     1321 ttctgtctga atacgacgaa catggcttgc agctgtctca ggaagtaaat aggtcttgtt
     1381 caaacgtgca atatcttctc ccaataaagt attattctct ttcatatgtt gaaggtaagt
     1441 tggaagagtt gcaagtagat tttccactac tttctgagca gcaatttctc gagtaaaaat
     1501 atcatacaag gcattgattt cctcttgtgc ctgtccattc tcatattcgg cattatccaa
     1561 ttccaactga cgaatattct cttggttttt cttgaatgct tcataaagca agtggaaacg
     1621 cgcttcaata tccgtttcaa caaaatgata attagcatca attagtttac gataaccggc
     1681 ttccaaatcc tgtaattgat ctggcaattc tgtagaaagc gtcgtaacca aggctggaac
     1741 acgatccaca atatgactta aggccaaaat gtgattttct gtattatcca aaatcactgc
     1801 ggcttccaca gggtcacccg atgaattcaa ggttacaaat tgtgaaaatt cagattggat
     1861 attttctaat tgtttttcaa tttcatccaa ggcttgacca tactgttctg aattttcagc
     1921 aactctatgc tgaagttcct caaataaatc caaagcatga agaacacgac cactattttt
     1981 agattcttgc ttctctaagt ctgccaaagc attgcgaatt gccgcaatat cttcttcaat
     2041 caaagtaatt tgactctcaa tttggtcaat ttgatgactg gccttgagaa aacgaaatga
     2101 atggttatag ccttctgctt caaagagatt attttcaata tcggcaaaag agttgagaga
     2161 taaatcgacc catttttgat tccattcacg gaaagccact tgactttgtc caatcaagtg
     2221 catatttttt acagcttcta cttcatcatt tactggaaga ttgtatagtt cttcttttct
     2281 ttcttctagc gcctctaatc tcccctcgtt tcgcttacgt agaaagattg ccactacata
     2341 agccagaact aaaatgactg caattgcaac cattaaataa attagttgtc cattagacat
     2401 atcaaactcc ttttttactt gaaacaatcg taacgattat atcatatttt ttagaccaag
     2461 ggaactactt ctccctattt tttagacatc aagtgtacta tagacagcat tttcttcgat
     2521 aaactcacga cgaggctcta ctcgatcccc catcaacata tcaaagattt tatctgcttc
     2581 tgcagcatca tctacagaaa ctctagccat caagcgatgt tcgggatcca tggttgtttc
     2641 ccacagctga tgatcgtcca tttcacctag ccccttataa cgctgaatag tcggtttggt
     2701 acgactttca ctataacggg ctaaagcttc ttggagtttg atttcttgat ctgcacccgg
     2761 ctggatatat tctttaatct cgcttccaac cttgacacca tagattggtg gctgggcaat
     2821 ataaacataa ccagcttcta ggattggttt catataacga taaatcaagg ttaaaagaag
     2881 ggtacgaatg tgggctccat cgacatcggc atcggtcatc aaaacgagtt tttggtaacg
     2941 ggctttcgaa acatcaaatt ctgcgccaaa tcctgttccc atggctgtga aaagactacg
     3001 aatttcttcg ttagctagaa tcttatccat acttgctttt tcaacgttca aaatcttacc
     3061 gcgaattgga aggatagcct gaaactcacg gttacgacca gatttggctg atccaccagc
     3121 tgagtctcct tcgacgatga agagttctgt ttcagcaggg ttattagaag aacagtctgc
     3181 tagtttccct ggaaggttgg aaatttccaa accagatttt ttacgtgtga cttcacgcgc
     3241 acgcttggca gccacacgag ccttggcagc caaaattcct ttttctacga tacgtttggc
     3301 aatctgtgga ttttccatga ggaaatcgga gaaggcttca ctgaagaggc gattggtaat
     3361 cttgaccact tcgctatttc ccaatttggt cttggtttgt ccttcaaact gtggatttgg
     3421 gtgtttaact gagataactg cagttaagcc ttcgcgaaca tcttcccctg ttaggttgtc
     3481 ttcattgtct ttcagtaact tatttttacg agcataatcg ttgataacac gtgtcaaggc
     3541 tgtacggaaa ccttgttcat gcgttccacc ttcatgtgta tgaatattat tggcgaaact
     3601 catgacattt tcatggtaac ccgttgtgta ctgcatggct acctcaactg tgatatcatc
     3661 catctcaccg tctgtataga ttggtgtatc aaagattaca tccttgttct cgttgatata
     3721 ttcaacgtaa ctggcaatcc caccttcata atgataatgc ttggtttgtt ccaaaccttc
     3781 acgcttatct gtaattgaaa tttgaagacc gcgatttaga aaggccaact cttgaatccg
     3841 tttatttaat ttatcaaaat caaagattgt tgtttcagtg aagatttttg ggtccggtgt
     3901 gaagtgaaca gttgttcctg ttttatccgt atctccaact atttcaagat ctgcgacaac
     3961 atgaccacga cggtattctt ggtaatgaat cttaccattt ttgtgaacat gaacgtctaa
     4021 ttgagttgaa agggcattaa caactgacga ccccaccccg tgaagaccac ctgaaacctt
     4081 gtatccacca ccgccgaact ttcctccagc gtgaaggact gtaaagacgg tctcaacagc
     4141 aggacggcct gttttttcct gaatatcgac tgggatacca cgcccatcat ccacaacagt
     4201 aatcgaatca tctggctcaa taaaaacttg aatatggctg gcaaatcctg ccaaggcctc
     4261 gtcaattgag ttatcaacaa tttcccagac tagatggtga agaccttctt ttgaggttga
     4321 tccaatgtac atccctggac gcatacgaac agcctctaag ccctctaaaa cttgaatttg
     4381 actggcatca taatcctgtg cctgcagatt tttgatttct tctgtcatct tattcctttt
     4441 tcttatatgt ctaatacttg tcttaaattc acgatactgg taaacaagtg ggtatcaagt
     4501 cctgcagctt gacctgcttc gatatcaatc ggccgatcac caatgacaag accagagcta
     4561 atctgatact tttctcttaa ataaagcatg gattcgggat tcggctttct cttaaagcct
     4621 gagctagaag tcaccacttc tgtaaaataa gctgctatag aggttttttc taaaatttcc
     4681 aaaacctgat catttcgatg agagaccaaa aaatgatggc cacctttatt tgaaatgtct
     4741 tccaataggt cagaaactcc ttcaaataaa atcgggtgtt caagctctct ggcttcattt
     4801 tccttgtact tttctaaaaa attctctaaa ttgggagcga atgtctcaat cgcaaaagga
     4861 gtagaaacct ttaaagcttg atagacactg tcatggtctt gtgtgatacc atacagtgcc
     4921 aatgtttcaa caaatgcagc tgttgaagtt tcataattat ccagtaaagt tccacctaaa
     4981 tcccagatgt aatcgtgata tttcataccc ttcattatag cattttttta tgaaaaaagc
     5041 gatgatttcc ctgagttttc cacataaaaa acgagagaat aactcccgtt ttactgattt
     5101 ttaccaaaga catctcgata gagcattcct gttcgtaaac tctctgcgtc ccctcctagt
     5161 tgctccacca actcgtaggc aaaggcaagg gctgttgaag gaccccgact ggttgtcaac
     5221 tgaccatcta ccactactgt ttccttgacg tagtgaccat caaagatttg ctcttgaacg
     5281 ccgtcataac aagtgtatcg cttatttttc aatatctctg cttgattgag ggcaattggt
     5341 gccgcacaaa tggctgatag tttcttccct tcttgctcga agctttgcaa ttcttgaatc
     5401 aaggtctgat tatcacgtaa atgtgcagaa ccaggcatac ctccaggaag aacaatcata
     5461 tcatagtctg ataaatctcc atcaaagaca tgatctgctc ttacttggat tgcatgcgaa
     5521 cccgttactt gctcttcaaa accaaccata tcacatgtga tattggctcg acgcaagaca
     5581 tctacaactg tcaaggcttc aatttcttca aagccctgag ctaacataac ggctactttt
     5641 accatgattt tctccttatt taatttgttt taatacaacc tttttccgtt tgaatgggac
     5701 ttttccgctc ttttcttcag ctaaattagt ctggtaactc atcgataaaa gcaaaccaac
     5761 accaatcaaa ttactgataa tagctgatcc cccttgcgaa atgaaaggca agggaatccc
     5821 cgtcaaagga agtagtccag tcacagcacc gatattctca aagatgtgga agagcaacat
     5881 cataatcaaa cctgtggaaa tataagtgta gaactggtta tttgatttaa gagtaatctt
     5941 caacatacgg taaatcaaca tgagatagag ggcaataacc aggacagagc caataaagcc
     6001 aaaatcttct gcaataaccg taaaaatcat atctgactct cgaactggga taagcagatt
     6061 cgaagcatta aatccctgac caaataagcc accactccca atggcaatct gcccttgagc
     6121 ctgctggtaa gtcgttgttt gggcaaactc aaagggattg agccaagcca aaatccgatt
     6181 aatttggtag gtcggcattc caatttggtg aagaaaagct cgtccgtcct tgctaataaa
     6241 gatagctaag aaaccagcaa ctcctgttac agcagtcaca aatactggga taataatttt
     6301 ccaagaaacc cctgataata aaacgattcc tgagaaaatg gctacaaaaa ccaaagccgt
     6361 ccccaagtca ctttgaagtg ctaaaagaac taggactgga atggtaaaga gaatcatcca
     6421 gaaaattaac aaaaagtcca gcggaaccgt gcgtctccat tccttatgtt tctttgtaaa
     6481 ttggacaatg acacgagcca acatgaggat ataggatatc ttcataaatt ctgacggttg
     6541 aaatagggta attccattta ttgataccca gtttttggca cccgttgatg caactaagct
     6601 tggattataa aatacaatcg gcaagatcat aagtcccaag cctaaaatat atagaaaggg
     6661 ggtcaccttc caaagaaatt ctgtattaaa gagcatgacc acaaaaccaa tcacaagccc
     6721 caaggcaatc caggcgacct gctgccctaa aatgggcaga atattattgg gataatcatg
     6781 actaacggct atatagatag ccaccacacc gatgaccagt agaaaaaata ctggcaagag
     6841 caaactataa tcgactctag agtcgagaga acgtttcata tatactaacc ttatactttc
     6901 atacaatact atttatcaaa gttcattaaa aaatctatca atagcctcgt caacttcgga
     6961 tcgagagatg gttttaacag tcgcttcttc tgctagagat gctactattt gtttgccata
     7021 tcgttttccg acgattctcc tatccaaaat aagagttaag gaacgttggt attcacgtct
     7081 catacttctt cccaaagcct gttttaaacg aataatggcc attggcaatt gataatcata
     7141 aaaggcattt ttcccttctt gattcagttc ttgattaatc tttttcgtca agggttcttg
     7201 aggattttgg aaaggaagcc tcggtacaac ttgaatcaca aaaggatggc ttgaaaaatc
     7261 aactccctcc cagaaacttg ctgcaccaag caagatttgt tgttcacctt tttcaaagcg
     7321 tttctttagc tgatgaacat ccccattttt atactgggcc aagtggctaa ctgtaagtaa
     7381 atccgatact gctagaagca tgtctttagc ggtaaagaga accaaaatcg gttgctggaa
     7441 agcttgaatt tccactagta aagcagctac ctctctggca tagacttcta aggaggtttc
     7501 tgttaccaga gggaaatctt tgaccatgac cacttcttgt tcctgttttc cccgagattc
     7561 aatcttgaca aatttggctt caggatagcc taaaaggtct gccaaagaaa ccctctgact
     7621 aatctcaaga gtagccgata ctcccaagac ttggcaactc tcaggaagta aagaggacag
     7681 aagagtacgg cctgattttg tagaagaaat ctgaattttc ttttgactcg tttcagttac
     7741 ttcaagccag taatcacctt cagctgtaaa atagcgaacc agctcatcaa agccttctac
     7801 ttctaattct gaaaaatact gatggagatt gtccagagaa tctaagatat ttttcctaga
     7861 tttaccagac tgaaattgtt ctatcaagta gagacactca aagcgaatac tttctagtat
     7921 ccgttgttga accctgtttt cttctcctac taaagcctta tcaattaaat cgataataga
     7981 ttgtatatcg taggtctctt gaagcagatt ttctagagct aacaaaatct tttggacttc
     8041 atcaataatc agtaaacggt cactgacaaa ttcaggatta tcttcaagtc tggttacgag
     8101 ataggcatga ttagtcacta aaagcttgca agtctctgcc ctttcttgac tacgtttcca
     8161 aaaatcttcc gtcacaaata agctctggga tgataaattc ccatcatgac gaaggtctgc
     8221 tagaaaatgt tggtaacggt agagttgccc gatttcatcc aaatctcctg tctctgtctc
     8281 agtaagccag accaagactt gcattttaaa gcgtctaaat aagcgatttt catcattttc
     8341 ctgcaaggaa tgataaaagg catccaactt cagataattg tgtggtccct ttaagctatg
     8401 aatatctgta tggaacactt ccttgagacg tttaccttct tcttccatga tttgattttg
     8461 aagaatcttt gtcggaacac taagaacaat ttgtcgctct ttggattgag ataaagcggg
     8521 taagagatag ccataggttt tcccaatccc tgtcggcgct tgaatcagag agacaggttc
     8581 atctttcaat agcaagccaa cctctttagc aaaactttct tgttcctccc tcacttcaag
     8641 gttcaacaga gaaatatttt tagaaaagtc ttgagatagt tttcgtggct ccagagaagc
     8701 tgccgttttc ttaaaatata gaccttgaac ttggaccaag tctggagaag tcaggataga
     8761 ttggttgcga taaatttcct caataaccag gtaggactca tataggagag cgtcagccat
     8821 ttccagcaag cgttccaaga gacctttagg aagctgggtc atcttttccc gtaaaaaaag
     8881 aagtaattct gctgtagctt gggcatctga aagggctgtg tgtgcgtgtt taagaggaat
     8941 tcctaattct cgacacaaaa tcggcaagct atatttttcc agttcaggga aaaagacctg
     9001 ggccaattcg accgtatcaa cacgagggtt tcttagctca tagccttcaa aaaataaatt
     9061 ttccgccaag agattagcat caaactgaac attatgggct acaaaaatcc catcctccac
     9121 caagtcaaag atttttctgg caacttgcga aaaatcaggt gcttgcgcca gacgttggtc
     9181 tgtcaatcct gtcagttctt tgatatgagc atccaagggt tcatgtggat tgacatccgt
     9241 cgtatagtaa tcgacgattt ctccatcctc aatcacgaca attcccactt ggataatttt
     9301 agccttacta cctgtgctag ttgcctctaa atccaccaca acatagcgat taccaatcgt
     9361 tttcattata aaaaattata ccaaaaaaag ggccatttgg cacctgcaaa cataggataa
     9421 ttttcaaact caagaacact acttttctta aaaatcccat cgaatagagc attctagcct
     9481 gctgattttt ttaaaatagt gaagaaatac gaaaaattga gagaagaaat gtttgcatct
     9541 tccttctctc aacgaatcat gtattttatt taaccatgtc aggatcgtag tcataaaatc
     9601 ctgtatcaag gaaacggttt ttagggtgaa gtttacgaac ttcttcatcc agcaagaagg
     9661 cttggtcatg gctaaagttg ccctcttgaa tcaagctacg cgcttggata aagagttttg
     9721 caatctcaac aaagttctga ccaggagtgt agagcccttc tagtttccag cgagtaaagc
     9781 catgctccac caattctgtt aatttgatca tcaaatcaag gtcattgttg gcaaagatat
     9841 gggtcccatg attatcttca aaaatggaat agtggctctc tggatcactt ggctcagcca
     9901 agaagaggtc acgtttatgc gtcttttcat catcgatatg tgtaaagtta tagtagtttt
     9961 gcaagagcgg acgtttagaa tgatggatga cactagcacc gtaaaccaaa acttcagcag
    10021 gaatttccaa aatctctggc attttgaaaa gttcagctga tggaatttca cgcgccaaaa
    10081 cagcctcaga tgcgccagcc ttttgtcccc agaagttaat ctgacgactg ctagttacca
    10141 tggttgaagc atcgtagatg gtcttaaatg aataaccatc gcggttgact acgtaaaaga
    10201 cgcctgcatc cccaatcgta atatagtctg tcttgatttc ttccaagaag tctaagaaag
    10261 gcttgatacg gtccatcata tcttggtgca tgagagcatt gaccgcaacg atcaattcct
    10321 taccagcatc atgaaccaac ttagcgattt cacgtaattg gtcataacta aaggtcgttg
    10381 gcagacgaag gccaaaatct ttctcaccga catagatacg gtctacgcca gcttcgagta
    10441 gttgttcaac ttgttcaata ctttcagcag ttgctgtaat gacaatcttt tccataagaa
    10501 aaattatacc acatttctcc aaaatcagcc atgctttgaa aatgaaaagg gactttattc
    10561 tttttgtaac ctttctgtaa taattctctg ccgaaaaaat gataaaatag gtatgtactg
    10621 ttaaggagag aatcatgccc gtaagaaaat tacaatccta tgaggtagac tatcaagaag
    10681 aattaaacca gcagcttcct cattaccaag cttatacacc tgaagcgcaa tctgatgcca
    10741 atctcaagga aatcctattt tttattaata tcgctgtttt ttgtatctgt attgctatct
    10801 ttagttttat ctttttagca ttaaaattat caactgctct tgcctttgcc gcagcaatcg
    10861 gattcagctt acttgtttta aaagttcaac ggtctattat caaacgaaaa cgtagaagat
    10921 aaatccaaaa tatcgcccca attggagcga tatttttatt ttttcttttt agatggtgtc
    10981 tgaatggcaa tcttcacttc aaagattgtt cccttgggtt tattatcttt gacagtaaca
    11041 gttcctttta gagcatctac aatttgcttg gctagggata atcctaaacc aaaaccacct
    11101 ttttgccggg ttctagcttt gtctactcga taaaaacggt caaaaatttt ctttttatct
    11161 tctgtcgaaa taccgattcc attatcagaa acaagtaaat aaagattgcg atcggtcgcc
    11221 gagataagaa aatcaatttc accatcctcc tcagtatact tgacggcatt atcgaaaaga
    11281 atggtcatca gttgtttcag aagaagctga tctgtgacaa ttgttcgatg gatacgattt
    11341 tcaaaacgga agacacgatt attttccgaa gcaatcatct cgtagtttgt gaaagttgta
    11401 ttaaaaaagc tagttggaac ttctgcaagc tccggcttaa tcccatcatc tctccgagct
    11461 aagttcagca agcttgtcgt taaaaaacgc atatttcgga cttcttccaa actcgatgca
    11521 atgctttcgc tcacatccat aatggtagct tctggcttac gaaaaagggt ctctaagcga
    11581 ttttgcaaaa ctgcgagtgg agttcgtaac tcatgactgg cattttccac aaaagactgt
    11641 tgcttctgca tactctcaag caggggccta acactgaccc tagctagata gagactggca
    11701 agtaaagaca aaatccagaa actagccatc acgaccacaa tcaattgctc atgcttttga
    11761 ctagcctgct ccaactgact ggtattaatc aagacagcag catactttat attggttgaa
    11821 accgaactaa tattggtctc catcaaaatc acacgataga tttcttcctg cccatagcta
    11881 ttaaaaacct gaatctggta aatatgtcct agttctttct tttctaactt aatcttatcc
    11941 aagcccaaaa atcgatttcc agaaagaagt tgagtaaagt ctttatcaaa gagaatgact
    12001 tccgtattgg aactgacatt aggttttatt tctactttac tagcgtccgc cctagcattt
    12061 tctaaatctt taatctcttc tgttgcccta tttatagcca gctgaataac tgcttgagga
    12121 ttttcactca gtccatgaag cttatcgtcc accgaagtat aaagactcga atgcatgact
    12181 tgtaaaataa tcagagtcat tgtagaaaaa atcagggtga agacaccgaa gttgcggata
    12241 aaataactaa agtcatccgc ataccatgtt tttttaagtt tactgaacat cttttaaaag
    12301 atacccaaca ctacgcaagg tttgcaaatt ctctgcaaaa gtggttccct ttaatttctt
    12361 acggactttt gaaacataga cttcgacaac cgaaatcgtt gtatcactat caaatcccca
    12421 tagacggtca aaaatctgcg tcttaggcaa aatcacattt tgattttgaa ggaaataaac
    12481 tagtaaatcg aactctttcc ccagcaattc gacaggagta tcttcaactt taacggtatt
    12541 ggttgataaa ttaaccacga tattcccata agtcaaggtg ttttcattaa acttccctga
    12601 acgtttgaga agggcctgaa tccgcatttt aagttcttct aggtagaaag gtttggtcag
    12661 ataatcatcc gctcccagtt caaatccatg tcccttgtca tccaaacttt ccttggcagt
    12721 cataatcaga actggtgtcg taattccctt ttcacgcaat tcttttaaga cttggaaacc
    12781 atttttttct ggcaacatca aatccagcaa aatcaagtca tagacaccac tctcagcttc
    12841 gtagagacct tcttctccat caaatacctg cataacatcc gcaaaatcgt ctaaaaagtc
    12901 aaatactgaa tttgacagac ctaggtcatc ctcaaccaat aagattttta tcatgagaaa
    12961 ctcctcctta ttaaaactat tataccaaat ttgccttaaa aaaaactcaa ctctctgcat
    13021 tttacatgag atagctgagt tttcttttta ttttaggctt atttatgcat ttccgtattg
    13081 aagaacaact gcttcgactg cagctttttc acggctaatc aagtcaacac gtgctgtaat
    13141 ttccttgatt cccataccga tgttacggct aagagcaagg tcagaaagtt gcggctcaaa
    13201 gaactccttg tattccgcca agcgttgctg agtcttaaat acatgagcag gaaggataac
    13261 aaagctatca aagctcatat ctcctccaag ggctgcctta atccaagccc agttttcacg
    13321 cgcccaagac caagctgttt tctgagttgc ttgatgagct aggaattggt aataccaagc
    13381 agacaagtcc tgtggtttga ccacaaattt gtccttccaa gaagtaatca agttttggat
    13441 attatccgca tctgtactgt atgcaagagc tgctgccaac tggcgtttaa agacagcatc
    13501 tgttgcgtga gtataagtat caagataaag tgctaacaag tctttagtct catgatgttt
    13561 catctcatta atcagaactt gtgagcgaat agctgctggg agtcctgcaa gattctcctt
    13621 gtgtgttgcg aagatttggc tagcgacttg actagcttct gcatcatttg agcgaatcat
    13681 catcgaaaca gccagctgac gaaccaattc atcctcatct gattctccgt ctttagcttc
    13741 aaaaccaaga cggtcatagt tatgacgagc caatttagca accagtcctt tgaaggctgt
    13801 ttcagcatcc gttccttcat caataaagcg ctcaagggct gaaatcactt gagaaacagc
    13861 tgaaaccacc agataagact cttccttagc aagtttatca agaactggaa gcaagtctgc
    13921 ataagaaatg tgccctgcct cagccaacaa acgacgttct tgaacaattt gcagtttgct
    13981 tgtgttatca agtgtctcta gctcagcaag aacagcttct aacaagtctc cttgatagtc
    14041 ggtaatatag tgggcagtat tttcagtgtt gagacgaaga gctccttcat tttcagcaag
    14101 aagagctgcg tagccaggga tttcgatact ttcagtttcg agtgtatcag gcaagccttt
    14161 ccagttgcta ttgaggggca ccacccagag acggttcttg tcttcgttct caccgatgaa
    14221 gaattgtttt tgtgaaatct tcaagacatc attttcaact ttgacagtaa gaactgggta
    14281 accaggctgt tccaaccaag aatccatgaa ggctgcgaca tcacgtcctg acgcttgacc
    14341 aagggcatcc caaaggtcac taccaatggt gttgctgtat tggtgttttt caaagtaggc
    14401 atgcaaacct ttagcaaaat cagcatctcc tagccaacgg cgaagcatgt gcatgagacg
    14461 gcttcctttg gcatagacga tagcgccgtc aaagagtgta ttgatttcat ctggatgttt
    14521 aacttcgacg tggacagact gaacgccatc agtagcgtca cgttcaagag caagaggtac
    14581 tccacctgtt tggaaatctt caaagatatt ccagcttggt tcgatggtat ccacacagac
    14641 gtattccatc atattagcga aactttcatt gagccaaagg tcatcccacc atttcatagt
    14701 cacgaggttc ccaaaccatt ggtgagccaa ttcatgggcc acaacaaggg caacttgttg
    14761 acggctagca aatgtagagt tctcatcgac aaccaagtaa acttcacggt aggtcacaag
    14821 accccagttt tccatagcac cagctgagaa gtcaggaagg gcgatgtgga gagattgagg
    14881 aattgggtac ttaactccat agtaatcttc gtaaaactcg atagagcgaa cagcgatatc
    14941 cagtgagaaa tcaagatttg aaagtggatg tgctttggtt gagtagacac ctaccagggt
    15001 accattttta gttttagcgg tcaccccttg caaatcacca gcaacaaagg ccaacaagta
    15061 agaagacatg cgaggtgttg tctcaaactt ccagatacct gtttccttac ggttttcaac
    15121 atcgatttct ggcatgtttg acaaggccaa ttcaccttct gcttggtcaa agcgaagaga
    15181 gaggtcaaaa gttgctttgg cttcaggctc atccacacat gggaaagctt cgcgcgcaaa
    15241 atggctctcg aactgagtag acaagacctc cttcttgact ccatcaactg tataataaga
    15301 agggtaaatc cctgtcatgt tgtctgtaat tttaccagaa aaggcaagaa ccaattcaac
    15361 ttgaccagcc tcagccaatt cgatatgaag ggcttcattg tcatggtcaa ctgtaaatgg
    15421 acgagcttga cctgcaactt ctacagaggt gatttccaag tctttttggt ggagggagat
    15481 gcggtcactc tgtgcttgac cagtgatggt cactttccca gaaaaagtct tggtctcacg
    15541 actcaaatct aaaaataaat cataatgttc aggaacaaat tgcttaataa aatgttcaac
    15601 tgcttgcata gttttctcct attctaagtt taagagctgc tgctcttctt caaacaaact
    15661 tattatatca tattttgcct gagaaaaaag gattggacag cgatttccaa aactttcttc
    15721 cttctaatag tctacagtgg gtagaccttg cgaaattctt ctaaaacaac cttgctttca
    15781 ggtgtaaaag tcaatcctgc ttcacccaag cagtctctga aaaaatcctc atgaacctgg
    15841 cgccaataga caagtgtctt gtttccctca ccttccttat aggcatggtc agctgacact
    15901 cgattgaagg gtttaacaga aacctttgta atttcgacaa tgcagacaga ctgattttga
    15961 ctatctaaaa tgacatcgaa ggtccctact tggggaagtg gttcgtcttc tagtacatag
    16021 aggtcatagg ctgatgctgt tgctgtcttt tctcctttaa acaccaaatc cgctaaaagg
    16081 tctggttcaa ctccaaaagc ccaagcatcg atttcatctc cgatcaaagg attgatttgc
    16141 ttgtatttat tccacatttc ttgcggtatc atgggtactc ctttgtaatt ttttactttc
    16201 ttcttttatg tgtttaagat gatctggatg gtcaatctct aaatcaaaaa tctctggaat
    16261 agaactgtag tggataatgc acttgatacc caactgattc attttttgta tgaaagaagt
    16321 attcagatag cctgctacag caaaattaat cttgttcttt cttgctttat cctgcatatc
    16381 tcttagcata tctaacatta ttggactttc catatcatgc cattgactgt ttctcatagt
    16441 cgcaaaaaca aaggaagtca aatcattcat tccaactaca atctttgaaa tgcccgtttc
    16501 cagtatacta gataagtcaa aatacgctga cggtaattca atcatcgttc cgactttccc
    16561 agtaaagcca tactgacgca atactgtaat agcttgtttt aattggtcgg catcattgac
    16621 aaaaggaaag ataagagata gattgggatt ggtttgataa acttttgtaa cgacatgtgc
    16681 ttcagcctga aattcatcca aacacgccag taaacgcctg gttcctctat agccaaacaa
    16741 gggatgccct tcgtcaaaaa actctctagt ccccactaaa caattggcct ctgtattcgt
    16801 taattcagaa aaacgatacc aaacttcttc atctgagtac agggagcaga tagtctctag
    16861 ataatctttt acaaattgct gacaacttgc taatatgatg ttttgattaa gctctctcaa
    16921 caaatattcc ccacgaatca tgccgacgtg gtgaaatagt tgaggataaa ttttttcaag
    16981 aattttttcg ccactaaggg caagttgatt tctcatcatt caccttccaa ttcatgtaag
    17041 aagtcttgtc cagttctgga aatcctaata attcagactt aaccttcaag actaatggcg
    17101 atgcattttc ttctgtaatt tcttgaatat ccatccaaat atatccaagt gaatcattcg
    17161 caccatcaga cacagcttcc gaagtcgtaa cttgaggtgc actctcattc atttcaacat
    17221 catacaaggc catgacatgg tgaaccataa aattttttaa ctcttctctg acgaaaacat
    17281 cgtagattcg aggattagag tagcttctaa cagtaaatct cgtctcttcc ataacttctc
    17341 tagtcagcgt ttccgtcagt ccttcaccaa gttgctgact gcctccaggt agatcatacc
    17401 gatgttgata agggcctctc gttttttcaa tgcaaagtaa ctttccattt tcaaagcaaa
    17461 cagcgtagac tccaaagtgt tttttgattt ccatccaact cctcctactt caaagaccag
    17521 ccaccatcta ttgtcaagat ttgtccttgc atggcgctcg cttttccact tgctaaaaaa
    17581 agactaagct ctgctatttc ctctggctca atccagcgct tgattggggt ttcactagcc
    17641 acccagtcag ccaaaccacc tggttcaaaa tccgcagcgg tcatagctgt cttgactgct
    17701 cctggagcga taccaaagac ctgaatccca gcttcagcat agtctagagc caactgcttg
    17761 gtgaagccag ccaaggcatg cttggatgaa gtataggcgt gaccacctcc acctgctagg
    17821 ctagaagcaa tggaacacat attgatgatg attccctttt tattttccag catttgtgtc
    17881 aaataatacc gagtcaactc tactggaata atgtagttga tttcaaaaat ctcttgaatg
    17941 tcctgcgccg tttgttccaa cagtggtttg taatcatcca aaactccagc agtattacac
    18001 aaaacatcca cctgagggca ccagtcaaaa ataggttcca agtccaaggt caaatctctc
    18061 tgtaaaaagt gaaaatcacc ctctaagagt ggcttttcac cttggtcaac tccataaact
    18121 tgatagccct tctctaaaaa gaggcgagct tgagccaatc cgatccctga actcactcct
    18181 gtaatgagta cacgtttagt catgcacttc tacccaatcc gttgccaaaa catcacaaac
    18241 tgtcgggctc cacatggaaa aaccttctcc ttcgccagaa acgttgatta ggaaataagg
    18301 tgtcatttca agtgcaagcc cattttgctc gatggtatca aagagttgga catagttttc
    18361 cgcacctccc caaccagttc gtacatattt tctcttagcc tttaacccag gcaggatctc
    18421 ttcaaatgtc atgtttttct cctttaattc tacattcttc atttaattat aacaaaaaaa
    18481 ccgctttaaa acggcttttt gactgtgatt tatttacatc ttcttctact tacggcaaat
    18541 tattccctgc agcaagataa atttcatacc attcttttct tgttaagcta aagtttgccg
    18601 cttggctaac ttctctcaag tgcttaggat ttgtggtacc tacaactgcc tgcatttttg
    18661 ctggataacg caatatccaa gaaatggcaa tagttgaaga ggttactcca tatttaatag
    18721 ctaaacgatc aagtacttga tttaaagctt gaaatttctc atttccaaca aaattccctt
    18781 taaaataccc gaattgcaag acagaccatg cttgaatgac cacatcgtgt aattggcaat
    18841 attcaaaaat gctgccatct cgcatagctg cttgactatc ttccatatta acatgaaaag
    18901 ctgattcaaa tcctggagta aaagccgcac tcaattgtag ctgattaaca gctaacggct
    18961 gcttgacatc ttttttaagc aactccatca tcataggatt ttgattagaa actccaaaat
    19021 ctcgaacttt accttgttta taaaggagat taaaggcttc tgctacttgg tcagattcca
    19081 tcaaagcatc tggtcgatga aggagcaagc tatctagatg atcaatcttc aatctttgca
    19141 aaataccgtc tactgatttt ataatatagt ccttagaaaa atcaaaatag gtaaattctt
    19201 caatgcgaat gccacatttg gactgaatcc acatcttttc tcttaaatct ggacgatttt
    19261 ttaggacaag acctaacagt tcttcacaac gaccacgacc ataaatatca gccaagtcga
    19321 aggcattgat tccaacagaa agtgctgttt ctacaagctc ttcaacttct tttacagact
    19381 tatcttttat tctcatcatt ccgagaacaa tttctgataa ttctttgtca tcttgaccaa
    19441 gagttatgta tctcatcaaa tttttctcct ttaatttcta acattcttcc cttcattata
    19501 acaaaaaacc gctttgcaac ggctttttga ctatacttca ctccatttta tcttcttaaa
    19561 cccacggaac aagacaaaga ttccaataaa gaggacagct aaaggaataa cttttgtaag
    19621 gaaaacattt gaaattccca tccactcata ataacggagc agagaaccca ccacaagatg
    19681 ggcaataatc atactgacaa atggacgaaa gaccgcttct ttccaattcc aaataccgat
    19741 aactagcgaa atcgtaaaga cagacaaact atcccaggga gccggaatat aaaaggctcc
    19801 ttcttgtaca aaacttccta ttcctacata tcccataaca actagcagaa caagaatccc
    19861 aacgacaata taggtgccaa ttttcatttt aggagaatct tggactaagc accaacgtaa
    19921 gattgtggcc acaagtccaa atccaatcag aaaaataaga agttgcccta aaaatgtgag
    19981 caaattgact gttaagagag gacctttaga aaaatcactt agtagttgat aataacgtaa
    20041 taccgctagg ataagaattg gcgtcaaaag ggactctttg atagaactgc gaggtgctcc
    20101 cttgagaatc tctttcatta tttttttagg attcttacct agataatcct ctgcactcat
    20161 gccatctcgt tctgcttctg agaaatctag catcatcaaa tagatctgct ctctgagata
    20221 gtcttcatca tagagaaatc cagcaagatt aaaattttcc cacaactcct caaaatactt
    20281 ttgattctcc tcagaaaact catgtagcaa agcgcttgtt tcttcgtaat acttcatttt
    20341 cttcatggtt taacccccat tcttaatccc ttctactttt tgactcaaat cgtcccattg
    20401 ttgccaaaag actgagacac gctcttctcc ttctttcatt aatgaaaaat acttccgatc
    20461 tggaccatct ggcgacgggc gcatgtcgcc tcttatccat tgattttttt ctaacttttg
    20521 caacaaagga taaatagttc ctggaacgat agtatcaaat ccagcctctc gcaaagtctg
    20581 aaccaactca taaccatacc gctctttttg accaatcata tccaagacac aaccttcaag
    20641 aacacctttt aatagctgag tttctttcat cacttctccc ttctaatcta ttttgtaata
    20701 cctactagta acttcaccta tagtatatca cttctacact agtttgtaaa gcataatagt
    20761 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccctaccgta tgtatggtta
    20821 ctgacttcgt cagtttcatc tacaacctca aaaca
//
LOCUS       DAVDHZ010000036        20351 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000036 DAVDHZ010000000
VERSION     DAVDHZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.037"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(58..429)
                     /locus_tag="VUR46_001633"
     CDS             complement(58..429)
                     /locus_tag="VUR46_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET5457026.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQLA"
     gene            complement(488..1921)
                     /gene="glgA"
                     /locus_tag="VUR46_001634"
     CDS             complement(488..1921)
                     /gene="glgA"
                     /locus_tag="VUR46_001634"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET5457027.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(1918..2724)
                     /gene="glgD"
                     /locus_tag="VUR46_001635"
     CDS             complement(1918..2724)
                     /gene="glgD"
                     /locus_tag="VUR46_001635"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: protein motif:HMM:TIGR02092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET5457028.1"
                     /translation="MKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLA
                     KKDISEVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKK
                     EHPEKLRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQ
                     KIYTKVKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLF
                     PRVVIGEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(2669..4057)
                     /locus_tag="VUR46_001636"
     CDS             complement(2669..4057)
                     /locus_tag="VUR46_001636"
                     /inference="COORDINATES: protein motif:HMM:NF012398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET5457029.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPTMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     SLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHIDNKTQRGPDNFPFLFETFWL
                     KPNGCPQLRCSY"
     gene            complement(4601..6880)
                     /gene="pulA"
                     /locus_tag="VUR46_001637"
     CDS             complement(4601..6880)
                     /gene="pulA"
                     /locus_tag="VUR46_001637"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET5457030.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AVNDAPVWKTFEMKRGNSYSHNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQIIRLKTKTDAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKERLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(6992..8950)
                     /gene="ligA"
                     /locus_tag="VUR46_001638"
     CDS             complement(6992..8950)
                     /gene="ligA"
                     /locus_tag="VUR46_001638"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET5457031.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRKLVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMESLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTIVADAALSGLTVVLTGKLKRLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(9043..10221)
                     /locus_tag="VUR46_001639"
     CDS             complement(9043..10221)
                     /locus_tag="VUR46_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5457032.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANV
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(10301..11164)
                     /locus_tag="VUR46_001640"
     CDS             complement(10301..11164)
                     /locus_tag="VUR46_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET5457033.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFYNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(11167..13068)
                     /locus_tag="VUR46_001641"
     CDS             complement(11167..13068)
                     /locus_tag="VUR46_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5457034.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFCQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATVEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(13494..13769)
                     /locus_tag="VUR46_001642"
     CDS             complement(13494..13769)
                     /locus_tag="VUR46_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET5457035.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(13876..14715)
                     /locus_tag="VUR46_001643"
     CDS             complement(13876..14715)
                     /locus_tag="VUR46_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5457036.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDIEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKNHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            14856..15704
                     /locus_tag="VUR46_001644"
     CDS             14856..15704
                     /locus_tag="VUR46_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET5457037.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(15797..16714)
                     /locus_tag="VUR46_001645"
     CDS             complement(15797..16714)
                     /locus_tag="VUR46_001645"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET5457038.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            17152..17357
                     /locus_tag="VUR46_001646"
                     /pseudo
     CDS             17152..17357
                     /locus_tag="VUR46_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(17668..17961)
                     /gene="rpmA"
                     /locus_tag="VUR46_001647"
     CDS             complement(17668..17961)
                     /gene="rpmA"
                     /locus_tag="VUR46_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET5457039.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(17978..18322)
                     /locus_tag="VUR46_001648"
     CDS             complement(17978..18322)
                     /locus_tag="VUR46_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET5457040.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(18338..18652)
                     /gene="rplU"
                     /locus_tag="VUR46_001649"
     CDS             complement(18338..18652)
                     /gene="rplU"
                     /locus_tag="VUR46_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET5457041.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(18688..18775)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(18834..19397)
                     /locus_tag="VUR46_001650"
     CDS             complement(18834..19397)
                     /locus_tag="VUR46_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET5457042.1"
                     /translation="MTFCAGYVNAYTFIVRGNTLVAGQAGNVVFLSVDLIQNNVSDVR
                     DKLLTLIAFIMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIAFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILG
                     VPIMMSVFYLSMLFASWQKKVKEKASF"
     gene            19868..20167
                     /locus_tag="VUR46_001651"
     CDS             19868..20167
                     /locus_tag="VUR46_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET5457043.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         6261 a         4348 c         3541 g         6201 t
ORIGIN      
        1 acctggggac ttataatttg tccaactaat tttcctgtta aaagaccttc tttgacttca
       61 agctagttgg cagtgaaata ggcaatacca agggattttg ctaatctctc caactattgg
      121 tgtaaatcca ccagacacca gaccaactag gatgccattc ttttggagaa tagagatgaa
      181 ctctgggaca tttagcgata gatgaattga gttgaagacg ttatcaaaga ccaaaatagg
      241 aagaccttcc aacaaggaca ctctttttct taaactgctt tcaaagacca actctcctcg
      301 cattgcccga cttgtaatct gcgaaatttc cgcctcatga cctgcctctc tccctaaaag
      361 atcaatcact tcttctagga ttaaggttcc atctacatcc aaaacacaca agccttttac
      421 ttgagacatc agttctcctc tctaaacagc ctaaaaatcg tatgaagtca tcatacgatt
      481 ttatctatta attaactaaa ctatggtaca agtcaaggta tgacttgcag gctgtatccc
      541 atgagaagtc actctccata gcttgttttt gtaggtttct ccaaatgtct ggatggtttc
      601 tatacaagtc caatgctgtt tggaaagtcc aatttaacca ataaggagat agattgtcaa
      661 agctaaagcc agtaccgctt ccttcgattg gattgaaagc gcgaactgta tctcgcaagc
      721 ctccaacttc atggaccaat ggcaaggttc cataacgcat agccatcatt tgagacaagc
      781 cacacggttc aaaacgactt ggcatgagga agaggtcaca agcagcgtag atttcctgag
      841 caagtttgac atcaaaagtg atatttgttg atagcttgtc tgggtaaatc tgagcaaacc
      901 atgagaaagc tccttcaaag gctggatcgc cagttcccaa aagaacaatc tgaacatctt
      961 cttgcaagat atggtgaaga ctttcgacca ccacatcaaa acctttttga cgtgtcaaac
     1021 gagaaacaat tcccaccagt ggaacgtctg ctctaacagg caagccaact ctttcttgca
     1081 attttgcctt atttttggct ttcccagaca aatcttcctg attgaaatga tagtctaaaa
     1141 gagcatccgt ctgaggatta taaagatcag catcaatccc attcacgata ccagatactt
     1201 taccagactc cattttaaga atctgatcca aattacatcc aaactgacta gtcataattt
     1261 catgagcata gctaggtgaa acagttgaaa cacggttcgc atagagaata cctgccttca
     1321 tccagttcag acagttgttc catcgaaggg tgccatcagc gtaacgttca aagccaactc
     1381 caaacaaatc acccaacatt ccttctgaaa attgtccttg gaattctaaa ttatgaatgg
     1441 ttaaaactgt ttcaatgtcc tcataggctt gaatccaacg gtatttttcc ttcaacaaga
     1501 aaggaatcat agctgtatgg tagtcatgaa catggagaag atcaggaata aagtcaatcc
     1561 tttccatagc ctcaatggca gccagttgga aaaaggcaaa gcgttctccg tcatcaaaat
     1621 caccgtaaac atgaccacgg aagaaataat attgattgtc aataaagtag aaggttacac
     1681 catttaatac tgttttctta attccacaat actgtctgcg ccaaccaacg ctcacctcaa
     1741 aatgaagcac atcttcaatc tgacttccaa atttagcctc taccatatca tagtagggta
     1801 aaatcactgc aacttcgtgc ccagctttta ccagtgattt tggaagagcg ccaatgacgt
     1861 ctcccaaacc acctgttttt gaaaagggtg caccctctgc tgctacaaat aaaattttca
     1921 tgaatgaata tcctctgtta ctttagcacc tttcttaacc acaactggat gttctgcagt
     1981 tcctcgaatc acaacaccag gctcaacttc aacccctttg tccaagatag catattcgac
     2041 ctgagcccct tctccaataa caacacgagg gaagagcagg ctatctttaa ccaagctatc
     2101 cttatggaca tgaatattac gtgatagaac agaattagct acttgacctt caataatact
     2161 accagaggca aactgagaag tgcttacctt agatgtatta gcatagtaag ttggctcttc
     2221 gtttttgacc tttgtataaa tcttttggtt tggtgagaaa agagaataga atttttgtga
     2281 ttcaagcata tcgatattcg cttgataata agatttaaca gagtgaatat tggctagata
     2341 gcccgtgtac tcgtaggcga aagctccctc ttttacagcc aaatcccgta aaacatagcg
     2401 caatttctct ggatgttctt ttttagcttc ttcttccaag tgttcaatca accaaggtgt
     2461 atcaacgaca aagatatctg tagacatatt gaacgtttca gctgttgact tgctatcaaa
     2521 gagtttatga gaaagaacat ggtctgtttc atctacatcc aagattgcat ttacttctga
     2581 aatatctttc ttagctagtt ttttataaac tacagtgata ggctcttttg ttgtactatg
     2641 taggtggaaa acttggttca aatcaatgtt aataagaaca tcgcagttga gggcaaccgt
     2701 ttggtttgag ccagaacgtt tcaaaaagga atgggaaatt atctggacca cgctgggttt
     2761 tattatcaat gtggactgta cctacttcaa gtttttcagc aatttcaaag gcttttttga
     2821 aatcatttgt aaagactgat gattgaaggc cgaattcaga ttcgttggca aaggcaatag
     2881 cttcctctac actagccaca cgaatgattg gtaaaacagg accaaatggc tcttcccatg
     2941 ccactttcat atcttttgta acttggtcaa aaagcactgg ccagagaaga ttgccctcac
     3001 gtttgattgg tgtaagagcc tgagcctctt tttcttgtgc atcctcaatc aagctccaaa
     3061 tgaagtcggc tgaagcattg tcaataacag gtgtaatatc agcattgtca aatggatcac
     3121 caactgttaa tttagaaact tcttcctgaa gcaaagtagc taatttatct gctacacttt
     3181 cgagaacaat gacacgttta atggccgtgc aacgttgtcc tgagtagcta aaggctcccg
     3241 caacaatttg cttggcagca tgttccaaat ctgcatcttc tagtacaaga gctgcatctt
     3301 tcccaccaag ttccaacatg gtaggacgca taccagctaa acgaccaata cgttctccaa
     3361 taggagttga acctgtaaag ttgatgaagt tgacttcttt gtgctcaatg atataatccc
     3421 caatttctga accacgacct gtaatggtgt tgaaaacacc tgccggaatc cctgcttctt
     3481 caaatgcttt agccaacaag agtccagaaa tggaaccttg tgttggtggc ttaaacatga
     3541 ccacattccc tgcaatcaag gcaggtgcaa ttttagaagc agataaatta actggataat
     3601 taaagggagc aatcgctagc acgataccaa ctggttcacg acggacaaca gccagtttgt
     3661 ttttacttgc tgcctcaaaa ccaccacctt ccattgcttg tccagtgata cggagacctt
     3721 cctcagcagc ataacgaatc aagtctgctg tacgcactac ttctccaatt gctgctttaa
     3781 tcccttttgc tacttctttg gcaaggatag taccaatttc ttccttatcg cgttctaaaa
     3841 tagctgctgt tttatgtaaa taagccgcac gttcaactgc tgataaagct cgccatgctg
     3901 gcagggctgc acgcgcagct tgcatagcct catcagcttc agtctgagtc atggctggaa
     3961 ctgtacccaa ttcttcttga ttgattggtg aataaatcgt aatttcttgt tcagatgatt
     4021 tccattttcc atttactaaa ttctgatatc ttgtcaaatt ctcatcctcc tgaaaatgat
     4081 taagatatat tttaccaaat tttcagaaaa tcacaaccct ttttgcaaaa tttttgagat
     4141 tattttcaca agcttgattt ttcaaagtat actcaataaa aataaaaaaa atccactacg
     4201 tcaaggcaag gctaatgtgg tttgaagaaa ttttcgaaga gcgtgaatga gtatcatcta
     4261 tagtaaaata aaaaactgaa caatttggtt ggggacaacc aaaccaattt ctcacaatgt
     4321 tttagaaaca agggtgtgct attccaattt cagcctacta taactgtcat agattgctga
     4381 aacaaagtct agataaaagt cttcataata acaagacccc ctatccagtg ttcaaaaact
     4441 ttgataggag gtcttgtttt gtgaaaatat ttatcaaatt ttctatacaa gtgagctgtt
     4501 agccagattc tttctattct ttcaatttca ataaatggat tttttaccaa tactcataac
     4561 tgggaatttg tctgtgtaaa aatagcgaga tagatggtat ttataaaaca ctcaagacag
     4621 ctagactaat atcatttaaa acattatctt cttttgagcg actgttggtt accaacatag
     4681 ctaaatttcc tgcattttca aattgatagg gttctgattt agcattcaca accaccaaga
     4741 ggcgttcttt gccgtgaact tcatagataa ggcagccgct atgttcaatc gcagaatgca
     4801 caaagacatg atggtaaatt tcatcatagc tagagtaaga aaaggcatca gtttttgtct
     4861 tcaatcggat gatttgacgg ataaactcaa tactgtcttg acgctcatta atcaagttcc
     4921 agttcacttg gttcacactg tcaggagcat tatagctatt catcgcacgc tctctatcat
     4981 catgggtcaa ctcaccattt tcaccagtcg caaccagttt ggtacgacca aattcttgac
     5041 cgatttccat aaaggccatc ccctgcatga gcagattcat ggctgtggca gtttcgacct
     5101 tgcgcatgat ttgctctgaa ctttggtctg gatgaagggt tgccaataaa tcgtgaagat
     5161 tgtaattgtc atgggcttct acatagttaa gcacctgatt tggatgtgta tagcttccta
     5221 attcacgact tcctaggatt gctttagcta gaattggctc tgtcgcagca ccactgacaa
     5281 aacctgactt gatagcacca taaacttctc cccctttgac agcatcgcgc tgattgtcat
     5341 taaagaaacc aatatttggc atctggtagg cattgtcctt cttggcctta tcataagggg
     5401 caagacctgt tcccatgtcc catccttctc catagaggat aatgttggag tcgatttcat
     5461 ccaagctttg acgaatcatc tgcatggtct tgacatcatg aatccccatc aagtcaaaac
     5521 ggaagccgtc aatattatat tcctgcaccc agtatagaag agaatcaatc atatacttgc
     5581 gaaacatttc gtgttcactg gctgtttcat ttccaacacc cgttccattc tggaaggtac
     5641 catctggatt catacgataa tagtaatcag ggactgttgt ttggaatggt gcatcaacaa
     5701 ctgagaaggt atggttatag actacatcca taatgactcc aatacccgca tcgtgataag
     5761 cttgaaccat caccttcaaa tcacgaatga cctgagctgg atcatctgga ttagttgaaa
     5821 aactagtttc tggcgcgtta tagttttgtg gatcataacc ccagttgtag gttacatttc
     5881 catcctcatc gtattcttta tgacggtctg caattggttg caattgaaca taattgtagc
     5941 ccagcttctt gatgtaatca aaagcagttg actggccgta ttggttaact gttccagcct
     6001 gagcagcacc caagaaagtt cctcgaagat gttcatctac acccgatgta ggtgatttag
     6061 tcaaatcacg aatgtgcatt tcacagataa ctgccttaca tggattttcc aagcgccaag
     6121 tagcctccga accgtgctta acctcgaagt tttcaacttg cttttctaca tggctcagaa
     6181 tagctgaacg tttgccatca gggctggtcg cgattgtata aggatcacgt gtcagtgttt
     6241 ggtgatgagg gaattggact tgatactgat aagccttacc taccaaatct tcctcaacat
     6301 ccaaactcca gacaccgatt gtattgtcct tatgattatg agagtagcta ttgcctcttt
     6361 tcatctcaaa agtcttccaa acgggtgcat cattaacagc tgattcataa acgacaactt
     6421 gcacttctgt cgctgtaggt gaccagaggg aaaaatgagc ctgattgtcc tctacacggc
     6481 aacccaattc tccttggtaa ccccaatgat gatcaaaact agcactgtta atggccttat
     6541 caaaggcaaa aggattttga tttttataga aaggactggc aatagcagga ttttcagagt
     6601 aataaatcct atcatcgcct tccaaaatcc agacctctgt taatagggga tagtgattaa
     6661 aacggataga atattcttta ctagtttgac ctgtatgaac cacaaaattt aagctttcta
     6721 taacatgtga acttgggtgt tcaaagctaa ataaagctcc aaaataatct tctttgtagg
     6781 ttagcaaatc aattcgttga tcctgacttt ttacaaagga gcaagtgtca tattctccat
     6841 tcttacgatg gtaatgaatg cgcatagggt agttatacat tttttatttt tcctttttac
     6901 tttgtttcta tttcactaat aaatttttgt caatctcgtc tcaattaaca gacatagtca
     6961 tattctctaa actctgtttt taaacgatcc attacaaact ttctagccat gcctcatctc
     7021 tgacctggat accaagttct tgtgcttttt gcagtttact tccagcgtct gcacctacca
     7081 cgacgaggtc ggtcttttta gaaacactac ctgtcacttt ggcacccaga ctttcgagtt
     7141 tacttttagc ttctgagcgc ttgagtcgtt tcaattttcc tgtcaatacc acggtcaaac
     7201 ctgacaaggc cgcatccgct actatcgtct gtcctttata gtccagattg accccagttt
     7261 ctttcaattc tctgagcaga atttcagagc cttctgtcgc aaaataagtc tgaagacttt
     7321 tggcaatcac gccacctaga ctttcaatac tggccacttc ctctgaatct gcctgagaca
     7381 gattttcaat tgaatggaaa tattgaagta aaagctgact agccttgctt cctacatgac
     7441 gaattcccaa accaaataag agcttctcgg cagaattttc ctttgatgct tggatagcct
     7501 gatacagttt agcagcggac ttttccttaa ccccctctaa aaggaggaaa tcctcttctt
     7561 gcaaacgata aatatccgcc acatccttga ctaaattagc agcaaagagc ttctcaacaa
     7621 tagatggacc aaggcctgta atattcatag catcacgaga agcaaagtga atcaagcttt
     7681 ccatgatttg agcagggcaa cgcggattga tacaacgtag ggccacttca tcttcaaagt
     7741 gcaacaagtc agagttacaa cttggacagt ttgtagggat atctagtttt tcttcagaaa
     7801 cccgtttgga ctctaccaca cgtaaaacgg cagggatgat atcaccagcc ttatatacaa
     7861 tgaccgtatc gtcttttcgg atatcttttt cagcaatata atctacattg tgcagggtcg
     7921 cacggctaac agtcgtaccg gcaagttgta ctggtgttag attagcagtt ggagttacaa
     7981 caccggtacg gccaactgtc cagtcaactg ataagagttg agcttctttt tcttcagcag
     8041 ggaacttgta ggctactgcc cactttggag ccttaactgt aaaaccaagt tcttcttgac
     8101 ttgctaggtc gttgaccttg attaccactc catcaatatc gtaaggcaga ttttcccgtt
     8161 cctgtcctac ttcttggata aaattccaga tttcatctat gttttcagcc aagattcgct
     8221 taggattgac cacaaaacct agttgttcta ggtacttcaa ccccttttct tggctatcac
     8281 gagttgaagg gctggcttct tgatagagaa acgttgcaag attacgcttg gcaactactg
     8341 ctgtatccaa ctgacgcaga gttcctgctg ccgcattacg aggattagca aattcaggct
     8401 ctccattttc ttggcgcgct tggttaactt ggtcaaagga agcgcgtggc atgtaacatt
     8461 ccccacgaac tgtgatatct agttcttctg gcaaagtcaa agggatgtcc ttaacacgct
     8521 tgaggttttc tgtgatattt tcaccaattg aaccatctcc acgtgttacc ccagcaacca
     8581 aaatcccctt ttcataagtc agcgagatag ataagccatc gattttcagc tcacaaatat
     8641 aggtcggatg agccacttcc ttacgaacac gcgcatcaaa agcatctagc tcctcacgtg
     8701 aaaaagcatc ctgcaaacta taaagaggat actgatgact gtatttttca aaaccatcta
     8761 aaaccttgcc accaacacga tgagtcggac tgtctgctag cacttgctct ggataagcag
     8821 tttctaactc gaccaactta cggtaaaggc ggtcatactc actgtctgaa accgagggat
     8881 tatcgctggt atagtactca gtcgcatagc gattgagcaa agcgactaac tcattcattc
     8941 ttttattcat aagaccattt taccataaaa caaaccctcc tcacaaacga gaagggcgga
     9001 aaaaacactt agtttgaaat tatttttgaa actcaagcaa ccttatatca atttttcaaa
     9061 atgagttcga acataaataa acgatataca agacaagatg ataacaccac ttccaattat
     9121 caggaaagaa gagagatgta cacttggcaa gactgtcata aatccttttg caataggcat
     9181 aaatagaata gctaaggtaa aaattgtact cagtactctc ccaagaaatt cgctctcaac
     9241 cttggtttgt acttgagtaa aaaagtgaat attaaaaatc gtcataaaca attcacaaac
     9301 taaatttcca gaaaaggaaa gaaaagttgg aagtggtaat cccatcataa aaactccgac
     9361 acctgtcaaa gccagtaaaa tcaaaagatt ataaacatta gctttaattt tactagctag
     9421 aagagcccca atgatggaac caatagcccc catagttaaa atacttgcat aggctccttc
     9481 tgacccgtaa agctgattcg aaaagggaag tagaaattca aaagctgcaa aaaagaaatt
     9541 aacgctggaa gctaccagca aaaggaagaa aatttcttgc tgatgccaga tatagtgtaa
     9601 cccatccttg atatctacaa aaatatctct cccagtaaaa gcctttttct cttgaacttt
     9661 tgcttcctct tttggaagga aagccactag aacaaaagca atgaaaaaag tcagcgagtc
     9721 tagcagtagc gtcatatgga gacttgcaaa ctgtaaaaca aggaaggaaa gaacaggaga
     9781 gctgacacct acaacctgca aaaccagctc taggcgagaa ttatagatca caatctcatc
     9841 tttctccacc acttcagtta tgatagcttt attggctgtg cgagaaaagg caaaagcaat
     9901 agcctgcaca atgttagcaa caatcaaagc gccaatcatc cagctatcat tccttatgaa
     9961 agaaatagcc agacaaagaa tcccacaaac aagatctgcc gtcattaaaa tcttacgacg
    10021 agaaaaacgg tctgaaataa ctccgccaaa gggattgacg agaatagatg tgacgagctc
    10081 agaaatctga tacattccta aaactgtctg tcctatagtc cccatagaag ccaaccagac
    10141 actatttcca taatcataga gcatatttcc cattttattg atagccccac ggctaatcaa
    10201 ctgcactgca tagcgattca tattaaagct cctctcaaat tttgaaacta ttgtatcaaa
    10261 accgaaagga gctttttatt ttttccctta tttgggaaaa ttaacttttg acaaattttt
    10321 cgtagtgttc ctgataatag gctacttgct ccggaagacc taacacatca aaaatatgca
    10381 tggcctcttg catctgctta cagccttctt tacactgtcc tttttgatat aaggcaaaac
    10441 cttttaaata atggaaaaca ttacgctcat aaagcttaat acctttgtca ataatcttct
    10501 ctgtataagc ctcaaaatag ttggcattat aaaaagaaga atgctctaaa caatgctggt
    10561 aacaatttag ggccaaaatc aaaactaatc tcttatggcg actaatctct tggtaaaatt
    10621 cctccctctc cataacttct ctaccaatcc gagtgacata gtctacatcg tagaaactat
    10681 agaggttacc gaaaagaatc aactcataca tggtccattc ttctgttttg aagagataat
    10741 ctgctacctt atccaaatca tcctgcttca tatcataact cgcatctctt tgacaaatca
    10801 gaccttgtag caaaatccag ttcagctcaa aataaagggg agtcgtcgaa ctcttagact
    10861 tttcaagttg ttctctttga agcttttgaa aacctgcaat atcgtttgaa tagtaaagtg
    10921 ggataatctg tgccatcata gacacatgtt catgattata aaaattcctt gccttatcca
    10981 tgaaattttc gattgttaca tgaatattat ccaaaatctc aaagaaacgg gagactgcca
    11041 ggtcagactc cccaagctca aaacgagata actgagaggt agagcaggat tcgcctgctg
    11101 cttcctttaa agaataattt ccacttgttc gaaattcacg aaatactttt ccaagatgtt
    11161 ccatttttac acctgctctg ataattcttc ccactcaagc atagcttctt cctgacgatg
    11221 gctgattttg tccagctcag cctgtaattc catgagtttg tcggcatcgt ttgtttccaa
    11281 catttgttca gaaatggctt ggctttgact ttctagctct tcaatttcag cttctagact
    11341 ttcgatttgt cgcatgagtt tgcgaacttc tttttgactt tctttctggg cctgatagtc
    11401 attgactgga cttgcttcct ttgcttgatt gctagttgaa gcttcctcag tctgactcat
    11461 ttctactgtt gctttctttt caacatagta gtcgtaatct ccaaggtaga gagttgaacc
    11521 attctcagac aattccaaaa catgagttgc cacacgattg ataaagtaac gatcatgact
    11581 gacaaaaagc aaggtaccat caaagtcaat caaggcattt tctagcactt ccttactatc
    11641 aatatccaag tggttggtcg gctcatccag aatcaaaaag ttattgtttt ccatagacaa
    11701 tttagctaaa agcaaacgag ctttttcgcc accagatagc atgccgactg attttttaac
    11761 atcatctcct gagaaaagga aggctccaag acggttgcgg atttcaactt ctggtgtcag
    11821 tttgaaatca ttccagagtt catccagcac cgtattactt ggtgtcagct tgctttgggt
    11881 ttggtcatag taaccaacct caacattagc gccaaagcgc ttttctccct tgataaaagg
    11941 aatctggtcc acaatagact tgataaaggt tgacttgccg ataccatttg gaccaacgat
    12001 agcgacagca ttcatcttac gaagatctag gttgataggt tgtgacaaga cttccccgtc
    12061 ataaccaata gcagtatttt caacagtcaa aacaacattg cccgacgttt tttcagactg
    12121 gaaggtcatg ttggctgctt tcttaccagc ttcaggcttg tccaaacgct ccattttttc
    12181 tagttgttta cggcgagatt gagcacgttt agtcgttgaa gcacgaacta gattgcgatt
    12241 gacaaagtct tccagagcag cgatttcctt ctgttgcttt tcatagtttt ttgcctcagt
    12301 aactagcttt tgctccttca attcgacaaa acgagagtaa ttccccacat agcgatccaa
    12361 ggaatgcttg gtcaaatcta gcgtaattgt cgcaaccttg tccaagaaat aacggtcgtg
    12421 gctgacgata atgagggcac cgctatagtt taccaagtaa ttctctagcc aggcgatggt
    12481 ttcaatatcc aagtggttag ttggctcgtc caagaccaag agattgggct tttcaaggag
    12541 cattttggca agtgccaaac gagtattttg accaccagaa agctcagcaa ttttcatctg
    12601 ccacatagac tcgtcaaact tgaatccatt caaaatcgct cgaatatcag cttcataggt
    12661 aaagccacct gcttggcaaa aattctcaga taagcggtca taatctgaca tcagtttatc
    12721 caaatcctca ccagactttt cacccatctc cagctccatc tgacgcagtt gtctctccgt
    12781 ccgacgcaaa tcattaaaga catgaagcat ttcatcgtag atggtatttt cagactcaaa
    12841 acggctatct tgggctaggt aagacagaga aatatctttt ttcttattga tttctccgct
    12901 agttggctct tcttctccaa ctaaaatctt caaaagagta gacttacctg caccattttt
    12961 cccaacaaga gcaatccgat ctcgttcatc aacctgcagg ttgatattat cgaaaagaac
    13021 ctctcctgca aaagaacgtt caattttatt agcttgtaaa ataatcataa gagtagtata
    13081 gcatgtttcc ctaaggcatt caagataatc gtaagtcttt tagtacaact tttataacat
    13141 aaaataaact aaattatgta tattttatat tagattcctt cactatcttg ttggattttc
    13201 taaccagcta atcttgtttc aaatagttat cgcacaagtc tattatttaa ttcttttcat
    13261 catttacgta cgtatagcag attgaaataa gatgagaaca aatcgattgg gaaagtaaaa
    13321 ttaatttcta taaatgtttt agcaattgtt tcgtactatt ttagattcag tctactatat
    13381 acaatatttt cggaacattc aactttttaa ctctatttat tactagattt cataattaaa
    13441 aagcctactg accaagctag aaagcttgat acaataggct ttttaaagac tgattattta
    13501 acagcgtctt taagagcttt accagctttg aatgctggta ctttagaagc tgcaattgtc
    13561 atttctttac cagtttgtgg attgcgacct ttacgttctg cacgctcacg aacttcaaag
    13621 ttaccaaaac cgatcaattg aactttttca ccagctgcaa gatagtcagc tactgctgca
    13681 aatacagctt caactgctgc tgctgagtct ttcttagtca actctgtagc ttctgctact
    13741 ttagcgatca aatcttgttt gtttgccatg ttaatgattc ctccaaataa tttctaatta
    13801 acaaatataa tcatatccta aaatcccttt taggtcaagt taaaaacgct atttcttccc
    13861 attttattta tttttttagg agtggtaacg tatcaaaata gcccaagcgt tctcacccgt
    13921 gtgagtttga ataatggaac ccgtttccaa aacagaaatt ggcttttcaa cataagcttg
    13981 taagctttct ttcatctctt ttgcccaatc atcactacca gaatatgaaa ttccaatctc
    14041 tgctacagca cgttcagaaa gcgatgttat caactcatct aaccattttt taaatgtttt
    14101 agttccacga cctttaacca ttggctgcaa ttcatggttt ttcatttgca tgacaacacg
    14161 gatattgaga agagagctca acaagccagt tacacggcca attcgtccac ctttgacaag
    14221 attttccaaa gttgaaacac caatataaag ctctgtatgg tttttaacct cttctacatg
    14281 agataaaatt gcctctatat ctttaccttc ttgagctaac ttcgcagcct caacaacttg
    14341 gaatttcagg gcttggtcag tgaaggaact atcaacaaca gtcacatctg cagtagatag
    14401 gctagcacct tggcgtgctg cttctaccgt acccgaaaga gcatgggaca tatgaatagc
    14461 aagaatttgg ccaccatctt tgcataggtc ttcaaaaatc tcagcaaaga cacctacagg
    14521 tggctgactt gttttcggaa gattcttact ttcttgcatc aactgaagaa atttaccttc
    14581 ttctttcaaa tccgcatcag aataaacaac attatcaatc attacagata atggaacaat
    14641 tgtaatatct aattgcttta ctagttcagg ttcaatagta acagatgaat cggttacaat
    14701 cttaattttt gtcatagtat caatctttct attttaggat tcagattggt ttccttactt
    14761 ctaattatat caaaaaaaaa ttaaaaatcc taatggagtc aatcaaattt tccgtaaaat
    14821 ttgatataat caacttataa gaaaagaggt gtcctatgat taaaaaaatt taccccattt
    14881 ttaccatttt actaggtgct gctatttatg cttttggact gacttatttt gtagttcccc
    14941 atcatctctt tgaaggaggg gcgacaggca ttaccctcat caccttttat ctttttaaaa
    15001 tccctgtttc cctcatgaac ctgctgatta atattcccct tttcatccta gcttggaaga
    15061 tctttggagc caaatccctc tattctagtt tactaggaac cttagctttg tccgcctggt
    15121 tagctttttt tgagcatatt ccccttcata ttgatcttca aggtgattta ctaatcacag
    15181 cccttatagc gggaatccta ttgggaattg gccttggaat tatttttaat gctggaggta
    15241 caactggcgg aactgatatt ctagctcgta ttctcaacaa atacactcat atatccatag
    15301 gaaaactgct ctttatctta gatttttgta ttctcatgtt gattctccta atcttcaagg
    15361 atttgagatt ggtttcctac acgcttttgt ttgattttat tgtttctcgt gttattgatt
    15421 tgattggtga aggaggatat gccggcaaag gctttatgat tatcacaaaa cgtcctgacc
    15481 aacttgctaa ggcgattaat gatgacctcg gaagaggtgt tacttttatt tctggtcaag
    15541 gctactatag taaagaaaat ttgaaaatca tctactgtat tgtcggaaga aatgaaattg
    15601 tgaaaacgaa ggaaatgatt catcgaatcg atcctcaagc ctttataact attacagaag
    15661 cccatgaaat cctaggagaa ggcttcacct ttgaaaaaga ataaaaagag gtaatgtcgt
    15721 gacctcaaaa gttagactaa atcatctatc ttttgggtta cagacaacct cttttttgtt
    15781 ttatttattc aagctcttaa gaccaattcc gagttacttc ttcatcagcc tttaactgat
    15841 ccactaattg gtcaactgag tcaaatttgg tcatatcacg aatgcgatca agccaataaa
    15901 ccatgacggt ttccccataa atatcttgat taaaatcaaa aatattgact tcaaaacgtg
    15961 cttcttctcc atcaaaggtc acatttttcc cgacactagc catagcacga tacttctgtc
    16021 tttgaatctc aacatcaacg acataaacgc catctgctgg catataagta cggtctaaaa
    16081 gcactaaatt cgctgtcgga taaccaattg tacgaccacg agcattacca tgaactacca
    16141 tacctcttga tggaagcggt gcccccaaaa gttttcctgc ttctttcaca tttccatcta
    16201 aaatagcttg acggatacga gttgaactaa tctttccttt ctcatcttct acaggtggaa
    16261 caatgataac ttctccatca aagtaatcct ttaaatcttc tgctgttttt ttgtcagaac
    16321 caaatgtata atcaaaacct gcaacaataa ttttggcatt catagccttg atataagttg
    16381 caaagaattc ttgtgcagtg agactagcga attgactact aaaatcaagg agatataatt
    16441 cttctacacc ttcgcgcttt aattttcttt cacgttcagc agggttcaaa atatgcaaaa
    16501 acaaatctgg atgataaggc tctaaagcga tctttggaga ttcattaaag gtcataacga
    16561 cgataggcaa taaatccttt ctcgcagcct tgttggcaac acgaaataat tcttgatgcc
    16621 ccttatgtat gccatcaaaa tagccgagaa caacgactga atcagatggt gtgccaatat
    16681 ctttttggtt ttttatagga atagtaataa tcataaaata attatatcat agcgatagct
    16741 atttctggaa cagaaaatct gaaatgttgt ttttttcaca tgaagtgtac ctgttttcaa
    16801 aaggcacttt attctatcgt tgcttaacta tgaactttgc aatattcttc tcaaaaactt
    16861 gtaggacatc ttcaaaattt tgcaaggagt gattagactt gttcggtaac cataaagtgt
    16921 catactatgc ttatgtatga aaaagcaatg caactaactc ctgagaactt taaattacta
    16981 attggtgccg aaaaggtaga atttagaatc gaggtacacc tatggctgta aaatttacaa
    17041 aatgagacaa cttgggcaag atgtttgaag aatttcctaa actccctgat ttgaagcaag
    17101 tcactttccc tgatgacaaa gaaaaaagcc aaagcaataa agaaaaacta gatgactgct
    17161 ttccaacaac tcccatctag tgtgcttcag actgggctat ttttctctcc atctgttagc
    17221 ttggattctc agaccgtttc agctaaagaa tatcttttcc cttatcagaa ggaacggctc
    17281 aagccattca gacaagtgaa gggacgacaa gccaatattt gaaaccagat agcagttctt
    17341 atagtcaatt gaaataaaat ctgaagaaat cgagtaggaa actcatatca atgtttaaca
    17401 gtgttctatt ccagattcat actcaatgaa aattaaagtg caaactagga agttagccgc
    17461 aggctgtact tgagtacggc aaggtgaaac tgacgtggtt tgaatttgat tttcgaagag
    17521 tatcaatcca ctatacatat taaaaagtat gggtatcaaa ataaaaaaac aggctctccg
    17581 aaaactcgga aagccttatt ttaagctgtt tctagcttcc tcacctttac atttcaaggt
    17641 tcgggataaa aggttcaatg aaccttttta ttttgcgatt gggtaaactg aaacttgttt
    17701 tttatcgcgt cctttacgtt caaagcgtac tacgccttca actttagcga acaaagtatc
    17761 gtctccacca cgaccaacgt ttacacctgg atagatgtgt gtaccacgtt gacggtaaag
    17821 gattgatcca cctgttacag tttgtccgtc agctgcttta gctccaagac gttttgcttg
    17881 tgaatcacgt ccatttgatg tagaacctcc accttttttg tgggcgaaaa gttgcaagtt
    17941 gttaagagtc atttttaaca taatgttttc ctccgtgtta gttttctgtg ataactctgg
    18001 tttggacgaa ctcagaagag ttctccgata agtttgccat acctaagaaa aatgattcaa
    18061 agaataactg ggtcatttct ctctggtgtg aaggaagatc ttttggtatt tcaaccatca
    18121 gatagccacc ttcatcttcg tttaattcta ggattggttc atagcctgca aatttctcaa
    18181 tagaattgat aaagttaatg gcaagcgtag aaaccgatgc acacacgaca tctaagccgt
    18241 attcgccact ctcggcgtgt ccagtaattt ccgcactcct cagctcgcca tcttcggctc
    18301 tctcaaagac tgcctgtatc atgtgttctc cttaaaatta agcgttgatt gcgttgatga
    18361 caacttttgt atatggttga cggtgacctt gtttacggtg gctacctttt ttaggtttgt
    18421 acttgtaagt aaccactttc ttttgttttc cttgtttttc aacagttcca actacagtag
    18481 ctccagcaac aagtggagtt ccgacaacag tgttttcacc accaacaaga acaacttcgt
    18541 taaaagtaac ttcttgacca gcttcaacgt tcaatttttc aacgtaaact gcttgaccaa
    18601 cttcaacttt aacttgtttt ccgccagttt tgataattgc gtatgtgctc attatgcacc
    18661 tcctatgatt tttatgggtt tccccgattt tttgtgaaga ctcgcctagc atcgtgggac
    18721 gaaccactta aacttgaata atcaagcaac gatgttcgtg cggttgcaca ggatcgtgca
    18781 tagtcaactc ttcaagtata gcatatctcc tattttctta caagtaataa cacctaaaat
    18841 gaagcttttt cttttacttt tttctgccaa gaggcaaaaa gcatgctgag gtaaaaaacg
    18901 ctcatcataa taggaacacc aagaatggtc ttttcatgat agaaaatcgt caaataggct
    18961 gaaaagacaa cgccaaggac aaaactacta agcaggctaa caaatatgaa tccttcacgc
    19021 aaaaaaggag tgtgcttggt tcggaaataa tctccaaaag cagttgtcac cagtcccata
    19081 cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac aaaagcaata
    19141 atgattgata agattgccaa gggaatcaag gacagaatag attttttcac aattctcaat
    19201 ttttccttat aaatcgttaa taaaaagact cccattataa acgctattaa ggttaaaagc
    19261 ttatccctaa catccgaaac attattttgt atgagatcta ccgaaagaaa gacaacattt
    19321 ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc attcacatat
    19381 ccagcacaaa acgtcaaaaa agtgctaacc ttttagactg acgtgatatt tttcttatag
    19441 gtaataacct cattttccct cccattgtat tttctcttag aaatattgta ccattttctt
    19501 tctaaaaaat cgcaggctac catttagatt ttactattag cataaaaata ataatagaca
    19561 actatttatc caaaaataga tagaggtaac atgtttgcaa acaaagcata cgaaccttta
    19621 gtaaaatcat ttccatgaaa ctagaataga gcccctctta gcaaaaatca ttattttaat
    19681 ttatttctaa tcactccttg acataaataa ctctcaccaa taaaagacta tgtcttaaaa
    19741 aaatggtata ataaaatcaa tacttgggct tgatgactat gctactaata acaattagga
    19801 gagaaaatca ggcacttgtt aacaacaagg attatcccct tgagatgaaa ggaactttag
    19861 aaatcttatg atgaacatgc aaaacatgat gcgtcaagca caaaaacttc aaaaacaaat
    19921 ggaacaaagc caagctgaac ttgctgctat gcaatttgtt ggcaaatctg ctcaagatct
    19981 tgtccaagcg accttaactg gcgataagaa agttgtcagc attgatttca atccagctgt
    20041 cgttgaccca gaagacctcg aaaccctttc tgatatgacc gttcaagcca tcaactctgc
    20101 tcttgaacaa atcgatgaaa ctactaagaa aaaactgggt gctttcgctg ggaaattgcc
    20161 attctaaaaa caaggagcta gaacaatact tgtcgataac aaagactaag aaaggtgcaa
    20221 aaattatagg ctctataata tttgtagtgg gtaaattccc tatggatatt atggagccta
    20281 ttttgtgtag aaaaaaagtc ccatatgacc tataatgaaa agcgacaaaa caactcatta
    20341 gaaagaatca t
//
LOCUS       DAVDHZ010000037        20210 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000037 DAVDHZ010000000
VERSION     DAVDHZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.038"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(19..153)
                     /locus_tag="VUR46_001652"
     CDS             complement(19..153)
                     /locus_tag="VUR46_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET5457044.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFEINNSNIRYMIKLIDR
                     "
     gene            432..527
                     /locus_tag="VUR46_001653"
                     /pseudo
     CDS             432..527
                     /locus_tag="VUR46_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(780..1400)
                     /locus_tag="VUR46_001654"
     CDS             complement(780..1400)
                     /locus_tag="VUR46_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5457045.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1400..1882)
                     /locus_tag="VUR46_001655"
     CDS             complement(1400..1882)
                     /locus_tag="VUR46_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET5457046.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGNKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1882..2724)
                     /locus_tag="VUR46_001656"
     CDS             complement(1882..2724)
                     /locus_tag="VUR46_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET5457047.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2819..3619)
                     /locus_tag="VUR46_001657"
     CDS             complement(2819..3619)
                     /locus_tag="VUR46_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET5457048.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFFES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3763..5142
                     /gene="glmU"
                     /locus_tag="VUR46_001658"
     CDS             3763..5142
                     /gene="glmU"
                     /locus_tag="VUR46_001658"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET5457049.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVASISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            5152..5697
                     /locus_tag="VUR46_001659"
     CDS             5152..5697
                     /locus_tag="VUR46_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5457050.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5709..6023
                     /locus_tag="VUR46_001660"
     CDS             5709..6023
                     /locus_tag="VUR46_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET5457051.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            6040..6732
                     /locus_tag="VUR46_001661"
     CDS             6040..6732
                     /locus_tag="VUR46_001661"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET5457052.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIVTGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKTLD"
     gene            6809..7300
                     /gene="rocS"
                     /locus_tag="VUR46_001662"
     CDS             6809..7300
                     /gene="rocS"
                     /locus_tag="VUR46_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET5457053.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7398..7988
                     /locus_tag="VUR46_001663"
     CDS             7398..7988
                     /locus_tag="VUR46_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET5457054.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTNVPLKSFINGLTGITAETLKDAPPVEKVIKEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7997..9760
                     /locus_tag="VUR46_001664"
     CDS             7997..9760
                     /locus_tag="VUR46_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET5457055.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDTYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     SQEDPEYTDLLLKKALEFFEF"
     gene            10122..10845
                     /locus_tag="VUR46_001665"
                     /pseudo
     CDS             10122..10845
                     /locus_tag="VUR46_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            11124..11297
                     /locus_tag="VUR46_001666"
     CDS             11124..11297
                     /locus_tag="VUR46_001666"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457056.1"
                     /translation="MSDAVTIPTPTTPTLDKDGAKNEVEQAFSTKTSNIDKDNSLTNE
                     KNRSERISENSKR"
     gene            11251..11748
                     /locus_tag="VUR46_001667"
     CDS             11251..11748
                     /locus_tag="VUR46_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET5457057.1"
                     /translation="MKKIEVKGLAKTVKDKAIQNIENAQDETTLNTAKNNGITNIGKV
                     TLPRTTKKAEAKEAINAAAEAKKTEISNRFDLTIEDKSRALQQVDQEANDAKIAVDKG
                     VTNKDVEQAKVVGIDAINNINPQPTSRPLSTPQPQPSTPTQPDQGDTETPTTPSSPSA
                     QPSQL"
     gene            12035..12451
                     /locus_tag="VUR46_001668"
     CDS             12035..12451
                     /locus_tag="VUR46_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457058.1"
                     /translation="MKAALNSLKDVPANASDSKPAQDKKDAKQGTEDSKDSAKMTETT
                     SVPPGVIVVSLLVLLGVIAFWLVRRKKESEIQQLSTELTKILGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETEAKLVEELKSILAKLK"
     gene            12682..13389
                     /gene="ccdA2"
                     /locus_tag="VUR46_001669"
     CDS             12682..13389
                     /gene="ccdA2"
                     /locus_tag="VUR46_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET5457059.1"
                     /translation="METIVFSISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWLGLIRTLCFIAGISLIFFILGFGAGYFGHVLYANWFRYVMGVIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSVFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMAIPFLVLALASGIVMPYFSKLKRHMMLLKKIGGFLIILM
                     GILLLLGQVNVLAGIFE"
     gene            13400..13966
                     /gene="sdbB"
                     /locus_tag="VUR46_001670"
     CDS             13400..13966
                     /gene="sdbB"
                     /locus_tag="VUR46_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET5457060.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEEAKKTQAPEQSPKQQQQTPVQ
                     QIAVGKEAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPD
                     RDFEILTVIAPGIQGEKTVEQFPQWFQDQGYKDIPVLYDTKATTFQAYQIRSIPTEYL
                     IDSQEKIGKIQFGVISNADAEAAFKEMN"
     gene            14088..15479
                     /locus_tag="VUR46_001671"
     CDS             14088..15479
                     /locus_tag="VUR46_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET5457061.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLA
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWHIKLDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSQLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLMPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNTCTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMETWIAFLVALLIGSLI
                     YFTYGYKHSTIEE"
     gene            15622..16539
                     /gene="adcAII"
                     /locus_tag="VUR46_001672"
     CDS             15622..16539
                     /gene="adcAII"
                     /locus_tag="VUR46_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET5457062.1"
                     /translation="MKKQNLFLVLLSIFLVCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLDRVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQSKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            16547..19027
                     /locus_tag="VUR46_001673"
     CDS             16547..19027
                     /locus_tag="VUR46_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET5457063.1"
                     /translation="MKFNKKYLAGSVAVLALSVCSYELGRHQAGQAKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKKEGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQIAYRTANGVAVPHGDHYHFIPYSQMSPLEEKLA
                     RMIAIKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENHLSKKTQETHALVAKKESVASRDREFYDKAYNLLTQAHK
                     ALSENKGRTSDFHALDKLAERLNNESSNKVKLVDDLLTFLAPITHPERLGKPNAQIAY
                     TDDEIKLAKLAGKYTTEDGYIFDEHDIESDEGNAYVTPHLNHSHWIKKDSLSEAERAA
                     AQAYAKEKGLQAPNSTEATEAKTEATGTEAIYNRVKAEKKVPLEKIPNHLQYTVAVQN
                     GHFIIPHFDHYHNLKFAWFDEGLYSAPEGYTLEDLFATVKYYVEHPDQRPHSDNGWGN
                     ASDHVRKHQADQDSKPDENKEHEEVSEPTRPESDEEENHAGLNPSADNLYKPSTDTEE
                     TEEEAEDTTEEAEVPQVERSIIEVKITEAEALLAKVTDSRIQQNAMETLAGLQSSLLL
                     GTKDNNTILAEVDSLFALLKESKPTPIQ"
     gene            19225..20115
                     /locus_tag="VUR46_001674"
                     /pseudo
     CDS             19225..20115
                     /locus_tag="VUR46_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6462 a         3573 c         4218 g         5957 t
ORIGIN      
        1 tgaatgcctg ttccaacatt aacgatcaat caatttaatc atgtacctaa tattagaatt
       61 gtttatctca aatttatttg aaagcttctc taagctatat ccttgttttc taagttcata
      121 gatctgaact ttatcatcat aagttaattt cataataaaa acactccaaa agttagattt
      181 tttctgtcta acttttgggg tgcagttcat ttaacacctg ataatatgcg ttttttattt
      241 taaagacttt ttgaccagcc tcattttttt aacttgatac tcagtgaaaa gcaaagatta
      301 aactaggaag ctagctgtag gctgttcaaa gaacagcttt gaggttgcag ataaaacttg
      361 tgaggtaacc aacatatata atgtgaagct gacgtggttt gaatagattt tagaagagta
      421 tgagtttgga agttttaatg gataatgcaa gattccatag aatgggtaag ctagagttct
      481 tatgtgaaga gtttgggcat aaacttttac cttttcctcc ctactcatct tagtatagaa
      541 aagtgaatct gaaatagtac ataactgctt ctaaaacatt cttataaatt gatttaaatt
      601 ctcaaatcat attattcagt tcttatttca ttttgctcta caatcctgtt gagaagacac
      661 gtgttcatat caaaaaggta ttggcaagtt gcaatacctt tttacaaggt tcttttgtct
      721 tatttttgtt tcaactgact atatctccta tggttctagt tcagaaggct aggctataat
      781 tatgattgat aagaagtatc attccaagta ttgagagtga atgtttcaaa atcatgggtt
      841 tctataatgg tcaggctggc atttgctaga ccgccatctt tacgaagaag tggttcttta
      901 tagcctagga gagtacgaag actggcagta agattggcgc cgtgtccgac aattagaata
      961 cgctcagctg gactatcttt taatgatttg ataaattgga tggtccgctg agttgtacta
     1021 tagagggatt cggctccgaa cattcgagtg tcaaattgag caagatttga acgaaaagcc
     1081 tggatttgtt gcgggtaaat agcttccagg gttgcaattt tcaaaccttc taacttccca
     1141 agttgccatt cacggagatt aggaacgatt tctaaagaac agggggtatg gagttgactt
     1201 tggataatct cagcagattt gaccgctcga ggtaaatcac ttgaataaat ctgatcaaaa
     1261 ggaatttcct tgagatactg gccaagtcgt tttagggttt caatggattc aggaagaaga
     1321 ggagaatcac cgctagcacc ttgaaaacga ccttcttggt tccagagggt acgaccgtgg
     1381 cggacaaagt agagtttcat tacttgatgt cctccaaaat atctacaaag tctgccttta
     1441 caaagctagc caagtcttgt ggcgcgacga taatgctgtg tccgacttcg cctgcagaga
     1501 caatcattcg atccaaatct agagcaattt tatcgataaa aatgtgataa ttgtgtttct
     1561 gacgaattcc gacaggatta ttggctccat gaatgtaacc agttgttttt tctaagtcct
     1621 tttgtggaat catgctcact tttttattgc cagaaatttt agctagtttc ttttcagaca
     1681 agtgctgagt gatagggaca attccgataa tcggtccggt cttgtttccc aaaagcgcca
     1741 aggttttgaa aatctgatct cgttcataac cttgaggaag ctctccttct agggcattga
     1801 tttgaatccc ctgatgaggg atagctgctt tagataggat ttgttccacc aatgtttttt
     1861 tgattttaac tttttttgcc attatttata tttatcctcc aattgactca tccaaatacc
     1921 aagccagatt cccagcgcaa agaagaaggc gatgatgaca taaccgacaa gtgaaagtcc
     1981 tgtgtattgg atactttcag cgtttcctgc atttggaatt aagatcaaaa gggtacttga
     2041 taggacgata ccgatgatga aatgatagac gcgtgagtgg tagttgttta aggcataatc
     2101 catcaatttt gaaaaaacga tgagagttgc acctgcacca attccaatcg gaaagaaggt
     2161 tcccaagaga tcaaaagttt taaaaccagt caacatagga gcatagagtc ccaaaatcaa
     2221 aagtaaattc gatgggctga ggccaggaac caagacgcca agggccaata gtgcacctgc
     2281 taggacgaag ttaagaaagc tggcgcttaa ggttccaacg acaaaattta aggcatagag
     2341 tcctaatcca gaaatgataa aggttgtcca taaccaagct aaatcaatct tgtctcggtc
     2401 agattctcga gttgattctt tgaggaggct aggaactgta ccgataatag ctcccgcaaa
     2461 gctccataat acaaagacct gataattttc aagcaggtat tcaatcgggt aggaaaataa
     2521 gccgattccc agaagcatac cgatggcaac tggaataaag tacaaaacat tttctttaag
     2581 gtctttaaag ggatgggcca gaaagccaat cattcgttca tagattccta agattgctgc
     2641 tagaactcct ccggaaattc ccggtaggat aaatccaaga gcaattacaa tccctttaat
     2701 aacgcgtgct aaccatgaga gcatatattt cctccaacta tttctatttc aaaaaatcct
     2761 tactatattg tatcacaatc agacacaaaa agaaaaagca aatgataaac aaatgctttt
     2821 aaggttttaa aaagagtttt cgaaaggttt cttctttatt ttttaaggga gagataacgt
     2881 tgatatctaa atcgtggtca aagccggcaa tttttccttt agatgtgtat tggtgaatat
     2941 cataatctaa atcagtttta ggactgctct caaaaaatcc tgagtctgag ccgtaggacg
     3001 gaatccaaac agaggtaaac ttgcctgtat caatactgtg ttcttccatg aagtagacac
     3061 caacgtagat gccgatgttt ttagcaccta gtgatgctag ttttgctcga aaattttcga
     3121 caccttcgtt catattagac atggttttgt cttccacgtc aagccaatag taactagggc
     3181 tgtaaggaga ggcagcattg tagaaaactt cggcagcctt ttccatttct tggacacttt
     3241 ttccagctac ataagcgtag acagcaactg ggacattccg cttttgaagt tcagtgatat
     3301 gactcttata ggccttgtct attccattga taaatgaagc atcattttct tttgtcgttt
     3361 gagcaccact gtgaacacga acaatagcac ctgaaatatt ttgtgagagg gcatcgtagt
     3421 tgatttcctc aggacgctgc cagccagaga ggtcaataat cggtttgtct aagtgtttca
     3481 aagcctgtgc ttcaatctgt gctatattgg attttgtttt aaacgattgg ttgtcattaa
     3541 gtgggcgatt gatgattaaa atgaacatca taatccccaa aaaactaaat aaaataagtg
     3601 gatgaatttg ttttctcata tcttataatt ctaccctaaa aatcaaaaaa aatcaaaaaa
     3661 atgggttaag gaagagactt tagagcattt tttcattcaa gagtgcggaa tgatttgaaa
     3721 tatggtataa taaaagggaa tttctacaga aaagagaaaa ttatgtcaaa ttttgccatt
     3781 attttagcag cgggtaaagg gactcgcatg aaatctgatt tgccaaaagt tttgcacaag
     3841 gttgcgagta tttctatgtt ggaacatgtt ttccgtagtg tgggagctat ccaacctgaa
     3901 aagacagtaa cagttgtagg acacaaggca gaattggttg aggaggtctt ggctggacag
     3961 acagaatttg tgactcaatc tgaacagctg ggaactggtc atgcagttat gatgacagaa
     4021 cctatcttag aaggtttgtc aggacacacc ttggtcattg caggagatac tcctttaatc
     4081 actggtgaaa gcttgaaaaa cttgattgat ttccatatca atcataaaaa tgtggccact
     4141 atcttgactg ctgaaacgga taatcctttt ggctatggac gaattgttcg taatgacaat
     4201 gctgaggttc ttcgtattgt tgagcagaag gatgctacag attttgaaaa gcaaatcaag
     4261 gaaatcaaca ctggaacata cgtctttgac aacgagcgtt tgtttgaggc tttgaaaaat
     4321 atcaatacca ataacgctca aggcgaatac tatattacag acgtcattgg tattttccgt
     4381 gaaactggtg aaaaagttgg cgcttatact ttgaaagatt ttgatgaaag tcttggggta
     4441 aatgaccgtg tggcgcttgc gacagctgag tcagttatgc gtcgtcgcat caatcataaa
     4501 cacatggtca acggtgttag ctttgtcaat ccagaagcaa cttatatcga tattgatgtt
     4561 gagattgctc cggaagttca aatcgaagcc aatgttacct tgaaagggca aacgaaaatt
     4621 ggtgctgaga ctgttttgac aaacggtact tatgtagtgg acagcactat cggagcagga
     4681 gcggtcatta ccaattctat gattgaggaa agtagtgttg cagacggtgt gacagtcggt
     4741 ccttatgctc acattcgtcc aaattcaagt ctgggtgccc aagttcatat tggtaacttt
     4801 gttgaggtga aaggatcttc aatcggtgag aataccaagg ctggtcattt gacttatatc
     4861 ggaaactgtg aagtgggaag caacgttaat ttcggtgctg gaactattac agtcaactat
     4921 gacggcaaaa acaaatacaa gacagtcatt ggagacaatg tctttgttgg ttcaaattca
     4981 accattattg caccagtaga acttggtgac aattccctcg ttggtgctgg ttcaactatt
     5041 actaaagacg tgccagcaga tgctattgct attggtcgcg gtcgtcagat caataaagac
     5101 gaatatgcaa cacgtcttcc tcatcatcct aagaaccagt aggaacctat catggagttt
     5161 gaagaaaaaa cgcttagccg aaaagaaatc tatcaaggac caatatttaa actggtccaa
     5221 gatcaggttg aattaccaga aggcaaggga actgcccaac gggatttgat tttccacaat
     5281 ggggctgtct gtgttttagc agtaacggat gaacaaaaac ttatcttggt caagcagtac
     5341 cgcaaagcta tcgaggctgt ctcttacgaa attccagccg gaaaattgga ggtaggagaa
     5401 aacacagccc ctgtggcagc tgcccttcgt gaattagagg aagaaacagc ctatacaggg
     5461 aaattagaac tcttgtacga tttttattca gctattggct tttgtaatga gaagttaaaa
     5521 ctatatttag caagcgattt gacaaaagtg gaaaatccgc gtccgcagga tgaggatgaa
     5581 accttggaag tccttgaagt gagcttagaa gaagcgaaag aattaatcca atcaggtcat
     5641 atctgtgatg ccaagacaat tatggctgtt cagtattggg agttgcagaa aaaatagagg
     5701 aggtcagtat gggtaaatct ttattaacgg atgaaatgat tgaaagagct aatagaggcg
     5761 aaaaaatttc aggtcctcct ttgctagatg ataatgagga aactaagatt ttaccaacct
     5821 cttcttcccg ttttggttat gccaatccta aggatcatgg ttttagccag gaaaccttga
     5881 agattcaggt cgaaccatct attcataaaa gccgtcgtat tgaaaatacc aagagaaatg
     5941 tcttcaattc taagttgaat aaaatcttat ttgcggtcat ctttctcttg attttgcttg
     6001 ttttagcaat gaaacttttg taatagaaaa ggaattgaaa tgaaaatagg aattattgct
     6061 gctatgccag aagaactggc ttatctggtc cagcatttag ataataccca ggagcaagtt
     6121 gttttgggga atacctatca tacaggaacc attgcttctc atgaagtcgt tcttgtagaa
     6181 agtggaattg gtaaggtcat gtctgctatg agtgtggcga ttttggctga tcatttccag
     6241 gtggatgccc ttattaatac gggttcagct ggggcagtag cagaaggtat cgctgttggg
     6301 gatgtcgtga ttgctgacaa attagcctat catgacgtgg atgtcacagc ttttggctat
     6361 gcttatgggc aaatggcgca acaaccgctt tatttcgaat cagacaaaac ctttgttgct
     6421 caaatccaag agagtttatc tcaattggac caaaactggc atcttggttt gattgttaca
     6481 ggagatagtt ttgttgcagg aaatgacaag atagaagcga ttaagtccca tttcccagaa
     6541 gttttagccg tggagatgga gggggcagct attgctcaag cagcgcatgc cctcaatctc
     6601 ccagtcttag tcatcagagc tatgagtgac aatgccaacc atgaagcaaa catctttttt
     6661 gatgagttta ttatcgaagc tggacgtcgc tctgcccaag tcttgttgac ctttttgaag
     6721 actttagatt aagcggaaat ttgacagttt ttctagctta tgataagatt taagtaaaga
     6781 aaagctagaa aacgtttcag aggatattat gagtattgaa atgaccgtca gtgagattgc
     6841 agaggtctta ggattatctc gccaagcaat caataaccgt gtcaaagaat taccagaaga
     6901 agacacagat aaaaatgaca aaggggtaac agttgttacc agaagtggct tgattaagct
     6961 agaagaaatc tataaaaaaa cgatttttga agatgaacct gtcagtgaag atgtcaaaca
     7021 acgtgaactg atggagattc tagtggatga gaagaatgca gaaattcttc gtctttatga
     7081 acaattaaaa gccaaggatc gtcagttatc agaaaaagac gagcagatgc gtatcaaaga
     7141 ccgtcagatt gctgagaaag acaaacaatt agatcagcaa caacaattga cccttcaagc
     7201 catgaaggat caagaaaatc ttaagctaga gctggaccaa gcaaaagaag aagtccaatc
     7261 cactaagaaa ggcttttttg ctcgtttatt tggaggataa tcaaggagct gtttaggtta
     7321 aatgctaacc tgatggcttc ttttgtttgt gaatagtata gttgattaga acagagacag
     7381 tagaggagag gtacagaatg gaacgattag aagattacat tgcttttgac ttagaattta
     7441 atcagcacga aggacaaaca cacttgattc aagtatcggc agtgcgtttt agagatggtc
     7501 gggaaatcga tgcctatgat tcctatgttc ataccaatgt acctctaaaa agttttatca
     7561 atggtttgac agggattacg gctgagacct taaaagatgc tccaccagtg gagaaagtta
     7621 taaaagaatt ccaagagttt gtgggttctt tgctgatgat aggctacaat gctgctaaaa
     7681 gtgatttacc tattttagca gagcatggtt tagactatag ccaacagtac aaggtggatt
     7741 tgtatgatga agcttttgaa cgtcggagtt cagatttaca tggtattgcc aatctcaaat
     7801 tgcaaactgt tgcctcattt cttggatttc aaggtcagtc tcataatagt ttagaggatg
     7861 ctcggatgac ggcgcgtgtt tacgaatcct tcttagagtc ggatcaagct agggaattgt
     7921 tagagacaga aagtagctta tcaaacaatc cttttggtgg cttggacttg tctcaattat
     7981 ttgactagga gtgcctatga aacctgaaaa acctaaaaaa ttgggtctta aacagattta
     8041 cctcaatctt gataaaatcc tctttctatt tttcttgatt tttatgatag tggagtattt
     8101 gtgggtacca ttcaattcat ggttggctag cttcttatta gatcagacag gttatctttt
     8161 tatttcctat aacaatgtct tagccatcct tactcattct ccattgatta gtctagcttt
     8221 tttagccttg attgtaatta accttctggt tgcttatttt caaataggac tcctctttat
     8281 tggcgctcgt catctcctct ataatgaaaa gcgaaggcta attgagtata tccgcaaggt
     8341 tttccatgaa agttttggat ttatgaaaaa gctaacttgc gctaaagcct tgtttatctt
     8401 tttctatata gctatgcttt ttccttttat acggaaaatg ctgaagattt attatcttaa
     8461 taaaatcgtc attccagagt ttatccaagc ttatttagaa gatacatatt ggatgtggtg
     8521 gctgagcatc ctacttctat ctcttatctt tctctatgtc tctgtcagat tgatgtttgc
     8581 ccttccgaag attgtatatg atcagctgac tgttcgagaa gcagtgatgt ttagcttgga
     8641 gaaaaccaag aagagagtta ctttttatgc ttggaattta ttttacatct tgctcaaagc
     8701 acatttatta ttttatcttc ctttgattcc tttattattg gctcaaactt tggtagatga
     8761 tatcactcag agagagtctc tgattcttgg tattttgaat tttgtcgtga ttaaaaatct
     8821 ctattatatg gctctgactt attttttggt taaatttgtt tcatttttga caggaaagga
     8881 gctggatatg cttcctagga gagaaaaaga tcacatcgtg cgatggggtg tcatgacttg
     8941 tgccagtctt ttctttgcct tagaaggtta tatttatctg gaggctccca tggttcatct
     9001 acctcaactt atttctcacc gaggggtttc caatgcaaat gggattcaaa atacagtaga
     9061 gtccttggaa actacagcac aactcaaacc agacttggtg gagacggacg tgcaggaaac
     9121 aaaagatggg cagtttgtca tgatgcatga tgctaacttg aaaaatctag caggtatcaa
     9181 taaaagtcct caagacttaa acttggagga gcttaaaggg attgatattt ttgaaaatgg
     9241 ctaccagact aaaatttcaa gctttgaaga ttatctcagt cgagccaacg aacttggtca
     9301 aaaattacta attgaaatta aaaccagtaa aaaagatagt ccagacatga tgaaccgctt
     9361 tttagcccgt tatgctgcaa agctcaagat ttatggacat caaatccagt ctttagacta
     9421 ccatgttgtc gaaaaagtaa gacagtatga tgccgaactg ccagtttatt tcatcatgcc
     9481 ctacaattct gtctttccta aaacaagagc gacaggatat actatggagt actcaacctt
     9541 ggatgaatat tttgtaagca aactatggac aacggatcag aaactttatg tctggactgt
     9601 caatgattca gaagctatca gcaaatctct tcacttagga gtagatggag tgattacaga
     9661 tgatttggaa aaagttcagc gggaaataga agtatcccaa gaagatccag aatatacgga
     9721 tttgctcttg aaaaaagcat tggaattctt tgaattttag taataaaaaa gaggaacggt
     9781 tgttcctccc atgataggta agtattcttg tgaatgcttg cttttttgtg gttgcaatcc
     9841 gtttacgaga attgtttgta ttgttcttgt ttcaatttac tttatagtgc tttgaagttg
     9901 gaatgctaca ctataacttc taaaatatta ctagaaattg ggaagatttt taatttcttt
     9961 tccgaataaa tagatagaag catcaaatct agtaaattaa attatacttc ctgcgaaaca
    10021 aaatatggta tagtagttct atgaatgatg aagcaagtaa acaactaact gatgcatgat
    10081 ttaagcgtct tgttggtgtt cagcgtacca cttttgaaga gatgttagct ggattaaaaa
    10141 cagcttatca acttaaacac gcaaaaggtg gacgaaaacc taaattaagc ctagaagacc
    10201 ttcttatggc cactcttcaa tatgtgcgag aataccgcac ttatgaagaa attgcggctg
    10261 attttggtat ccacgaaagc aacttaatcc gtcggagcca atggggtgaa gtaactcttg
    10321 ttcaaaatgg ttttacgatt tcaagaactc ctctcagttc tgaggacacg gtaatgattg
    10381 atgcgacgga agtacaaatc aatcgcccta aaaaaagaat tagcgaatga ttctggtaaa
    10441 aagaaatgcc acgctatgaa ggctcaagcg attgtcacaa gtcaaggaag aattgtttct
    10501 ttggatatca ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat
    10561 atcggacaag ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat
    10621 cctcaagcac aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa
    10681 gcctgtaacc atgcgctatc taaggagaga agcaaggttg aaaacatctt tgccaaagta
    10741 aaaacgttta aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga
    10801 atgaatttga ttgctggtat taccaatcat gaactaggat tctagttttg caggaagtct
    10861 acggtagaaa atttggaaaa tgttgcaggt aaacgagtga tagttaaatc aacagcgaga
    10921 aattctaatg attctattgt tgaattttat ttaaataaca ctaaaaagca acaattactg
    10981 ctgtaaacgg aactgctagt tggacaccgg atgaagcatt acaagctgga gataaaataa
    11041 ctactagaaa catagctaga gacagagaat atataccagc tacttatggt ggaaatatta
    11101 atgtagaaag atctacatca gacatgagtg atgcggtaac aataccaact ccaacaactc
    11161 caacattaga taaagatggg gcgaaaaatg aagtagaaca agcattttca acgaaaactt
    11221 ctaatataga taaggataat tctttaacta atgaaaaaaa tagaagtgaa aggattagcg
    11281 aaaacagtaa aagataaagc tattcaaaat atagaaaacg ctcaagatga aacaacgttg
    11341 aacacagcga agaataatgg aattactaac ataggaaaag tcacgttacc aagaactact
    11401 aagaaagctg aagcaaaaga agccatcaat gcggcagcag aggctaagaa aacagaaatt
    11461 tcgaatcgtt ttgatttgac aattgaggat aagtcaagag cattgcaaca ggtagatcaa
    11521 gaggcgaacg atgctaagat tgcggtggac aagggcgtaa caaataagga tgtagaacag
    11581 gcaaaagtgg taggaatcga tgctatcaat aacatcaatc cacaaccaac ttcacgtcca
    11641 ctttctacgc ctcaaccgca accttctacc cctactcagc cagaccaagg agacacagag
    11701 acaccaacaa ctccatctag tccaagtgct caaccgtctc aattataata aaatgaaaca
    11761 gaaataggac aaaataatca ggataatcaa ataaattttt agcaatgttt tagaagtcaa
    11821 tatgtactat tctagtttca atataccata actgctccta gtcaacctgc aaatcctgtc
    11881 ccagctccaa gctcagctcc gactcaagat cctagagtgg tagcaagcgc ttcggctagc
    11941 tcaacgagca cgcaagctcc agctcaagag caagttgaca agttctgaac ttcgtgcctt
    12001 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgccttga actctctcaa
    12061 agatgtgcca gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgccaaaca
    12121 aggaacggaa gatagtaagg attcagctaa gatgactgaa acaacctcag ttccaccagg
    12181 agtgattgtg gtcagtctac ttgtcctcct aggcgtgatt gccttctggt tggttcgccg
    12241 taagaaagag tcagaaatcc agcaattaag tacggaattg accaagattc tcggacaact
    12301 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
    12361 ccttgatttc gtaaaagaag aaaatggctc agcagagaca gaagctaaac tagtagagga
    12421 gcttaaatca atccttgcta aactcaagta aaatgtgatt tctgaaacgt cagacctaaa
    12481 agacatttcc gttcacaaaa gcagcgacga gtaatccttg tcgttgcttt ttggctattt
    12541 ttggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgttcaagac
    12601 gaatttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatg
    12661 attaagaaag ttggttcttt attggaaacg atagtatttt caatctctgt ttttctagca
    12721 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
    12781 ttattggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
    12841 ttaggcttga ttcgaacact ttgctttatc gcaggtatct ctctcatttt ctttattcta
    12901 ggctttggtg ctggttactt tggtcatgtt ctctatgcaa attggtttcg atatgtcatg
    12961 ggagttatta ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta
    13021 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagttttt
    13081 ttacttggta ttacctttag ctttggttgg acgccttgta ttggtccggt tttaagttct
    13141 gtcttagcac ttgcggcttc tggaggcaat ggcgcctggc aaggagctat ctatactctt
    13201 atttacactc tgggcatggc cattcctttc ttggtcttgg ctctagcttc aggcatagtg
    13261 atgccttatt ttagtaaact caagcgtcat atgatgctac tgaagaaaat tggtggtttc
    13321 ctcattattt taatgggaat tttgttacta ttaggacaag tcaatgttct agcaggaatt
    13381 tttgaataaa ggagaacaaa tgaaaaaagt aatgtttgct ggtttaagcc tcttgtcatt
    13441 agttgtactg atggcctgtg gtgaagaaga ggctaaaaag actcaagcac cagaacaatc
    13501 cccaaaacaa cagcaacaaa cgcctgtaca acaaattgct gttggaaaag aagctccaga
    13561 cttcacattg caatccatgg atggcaaaga agtgaagtta tctgatttta agggtaaaaa
    13621 agtctacttg aagttttggg cttcatggtg tggtccatgt aagaaaagta tgcctgagtt
    13681 gatggaatta gctgcaaaac cagatcgcga ttttgaaatt cttactgtca ttgcaccagg
    13741 aattcaaggt gaaaaaactg tcgaacaatt cccacaatgg ttccaagatc aaggttataa
    13801 ggatatccca gttctttatg ataccaaagc aacaaccttc caagcttatc aaattcgaag
    13861 cattcctaca gaatacctga ttgatagtca agaaaagatt ggaaagattc aatttggtgt
    13921 tatcagcaac gcggatgcag aagcagcatt taaagaaatg aactagaatc gataaaatct
    13981 gattacaaga tgtagtcaga tttttttaga aaaacatttt ataaatattc acatatctcc
    14041 tatatttatg gtaaaataga atcatcattt tattttggag gtcaaagatg aatatattta
    14101 gaacaaagaa tgtaagtttg gataaaactg agatgcacag gcatttgaag ttatgggatt
    14161 tgattttgct gggtatcgga gccatggtag ggacaggtgt ctttacaatc acaggtactg
    14221 cagccgcaac tctagcaggt ccagccctag tgatttcaat cgttatttct gccttatgtg
    14281 tgggattatc agcactattt tttgcagaat ttgcctcgcg agtacccgct acaggtggtg
    14341 cctacagtta tctctatgct attttaggag aatttccagc ttggttggct ggctggttaa
    14401 ccatgatgga gttcatgaca gccatatcag gtgtggcttc gggttgggca gcttatttta
    14461 aaggcttgct ctctcaatac gggatagccc ttcctcaggc tttaaatggt acctttaatc
    14521 ctcaggcagg aacatttgtt gatttattgc ctattcttgt cttggcatta gtgacatcgc
    14581 ttgttttact caatgctaaa gcagccttac gctttaattc aattttggtc attctgaaat
    14641 tctcggcttt agctctcttt gttttagtag gaatttggca tatcaaactt gataattgga
    14701 gtaattttgc tccttatggt tttggacaaa tctatggtgc tagtactggt attatggctg
    14761 gtgcgtcctt gatgttcttt ggatttttag gcttcgaatc catctctatg gctgtagatg
    14821 aagtcaagac tcctcaaaag aatattccta gagggattgt cttatcactt tctatcgtaa
    14881 ccattctcta tgccttggtg acgcttgtct tgactggtgt ggttcactat agtcaactaa
    14941 atgtcgatga tgccgttgcc tttgctcttc gtagcgttgg gattagttgg gcagctaact
    15001 atgtgtcatt agtggctatc ttgaccttga ttacagtttg tatttcgatg acctatgcac
    15061 tatcgcgtat gatttacagt ttagcgcgtg acgggttaat gcctgctgcc tttaaagaat
    15121 taacaaaaac aagcaaggta ccaaaaaatg ctactatctt gacaggtcta gcttcagcag
    15181 tagcagcagg aatgtttcca ttagctagta ttgcagcctt cttaaatact tgtaccttag
    15241 cctacttgat catgctggct tatggtctga ttcgcttacg gaaagaaaaa ggaatgccca
    15301 aagctgggga atttaaaaca ccattggtac ctctgttacc cattttatca atcatcattt
    15361 gtctatcctt catgttgcag tataatatgg aaacctggat tgctttcctc gttgctttgt
    15421 tgataggaag tcttatttac tttacttatg gctataagca ttcaaccata gaagaataaa
    15481 gtggaagtct gttgagttgt tgaaactcag cagattttta tatgtgaaag aaatttcaat
    15541 ttttttctaa aaatatcttg acagattaaa tttttaggag tagaatgttt actagttaat
    15601 taaatggtta aggagttgtt catgaagaaa caaaatttat ttttagtctt gttaagtatc
    15661 tttcttgtat gcttgggagc ttgtggtcaa aaagaaagcc agactgggaa agggatgaaa
    15721 attgtgacca gtttttatcc tatctatgcc atggtcaagg aggtttctgg tgacttgaat
    15781 gatgttcgga tgattcagtc gagtagtggg attcactcct ttgaaccttc ggcaaatgac
    15841 atcgcggcca tctatgatgc agatgtcttt gtttaccatt ctcatacgct agaatcttgg
    15901 gcaggaagtt tagatcccaa tctaaaaaaa tctaaagtga aggtcttaga ggcttcagag
    15961 ggaatgactt tagaccgtgt cccagggcta gaagatgtag aagcagggga tggagttgat
    16021 gaaaaaacgc tctatgaccc tcacacttgg ctagatcctg aaaaagctgg cgaagaagct
    16081 cagattatcg ctgataaact ttcagaggtg gatagtgagc ataaagaaac ttaccagaaa
    16141 aatgcgcaag cctttatcaa aaaagctcag gaattgacta agaaattcca gtctaaattt
    16201 gaaaaagcga ctcagaaaac atttgtaaca caacatacag ccttttctta tttagctaag
    16261 agatttggac tcaatcaact tggtattgca ggtatctctc ctgaacaaga accaagtcca
    16321 cgacaactaa cagaaattca ggaatttgtt aagacctata aggttaaaac gatttttaca
    16381 gaaagtaacg cttcttcaaa agtagctgaa actcttgtca aatcaacagg tgtgggtctt
    16441 aaaactctga atcctttaga gtcagaccca caaaatgaca agacctattt agaaaatctt
    16501 gaagaaaata tgagtattct agcagaagaa ttaaagtgag gaaagaatga aattcaataa
    16561 aaaatatcta gcaggttcag tggcagtcct tgccctaagt gtttgttcct atgaacttgg
    16621 tcgtcaccaa gctggtcagg ctaagaaaga gtctaatcga gttgcttata tagatggtga
    16681 tcaagctggt caaaaggcag aaaatttgac accagatgaa gtcagtaaga aagaggggat
    16741 caacgccgaa caaattgtta tcaagattac ggatcaaggt tatgtgacct cacatggaga
    16801 ccattatcat tactataatg gcaaggttcc ttatgatgcc atcatcagtg aagaacttct
    16861 catgaaagat ccgaattatc agttgaagga ttcagacatt gtcaatgaaa tcaagggtgg
    16921 ctatgtgatt aaggtagacg gaaaatacta tgtttacctt aaagatgcgg cccatgcgga
    16981 caatattcgg acaaaagaag agattaaacg tcagaagcag gaacgcagtc ataatcataa
    17041 ctcaagagca gataatgctg ttgctgcagc cagatcccaa ggacgttata caacggatga
    17101 tgggtatatc ttcaatgcat ctgatatcat tgaggacacg ggtgatgctt atattgtccc
    17161 tcacggcaat cacttccact atattcctaa gagtgatttg tctgccagtg aattagctgc
    17221 tgcccaagcc tattggaatg ggaagcaggg atctcgtcct tcttcaagtt ctagtcataa
    17281 tgcaaatcca gctcaaccaa gattgtcaga gaaccacaat ctgactgtca ctccaactta
    17341 tcatcaaaat caaggggaaa acatttcaag ccttttacgt gaattgtatg ctaaaccctt
    17401 atcagaacgc catgtagaat ctgatggcct agtatttgat ccggcacaaa tagcatatcg
    17461 tacagccaat ggtgttgctg taccgcacgg agaccattat cactttatcc cttattcaca
    17521 aatgtcacct ttggaagaaa aattggctcg tatgatagct atcaagggac aaaatggtgc
    17581 agtcttgcca ggaatgcatt atttgaaacc agcaccaaaa ccgcaagttc aaccatcaac
    17641 tgagaaaaaa caaactgatt ttgcagtaga acaggttgtt agaaaagttg gagaaggcta
    17701 tgttgtggaa attgctggtg tcagtcacta tgtttttgct aaagacttgg ctaaggataa
    17761 gattgatgct attgaaaatc acttgtctaa gaaaactcaa gagacacatg ctctagttgc
    17821 taaaaaagaa agtgtcgctt ctcgtgaccg agaattttat gataaagctt acaatctgtt
    17881 aacccaggct cataaagcct tgtctgaaaa taaggggcgt acttctgatt tccatgcctt
    17941 agacaaatta gcagaacgct tgaataatga atcttctaat aaagtaaaat tggtagatga
    18001 tttattgaca ttcctagcac caattactca tccagagcga cttggcaaac caaatgctca
    18061 gattgcttat acagacgatg aaattaaatt agcgaaatta gcaggtaaat atacaacaga
    18121 ggatggctat atctttgatg agcatgatat tgaaagtgat gaaggaaatg cctacgtcac
    18181 tccacacttg aaccatagcc actggattaa aaaagacagc ttatctgaag ctgaaagagc
    18241 agcagctcag gcttatgcta aagaaaaagg cttacaagct ccaaattcta ctgaagcaac
    18301 agaagcaaaa acagaggcaa cagggacaga agctatctat aaccgcgtaa aagctgagaa
    18361 aaaggtacca ttagaaaaaa taccgaatca tttacagtat actgtagctg tacaaaatgg
    18421 tcactttata attcctcact ttgatcacta tcataacctt aagtttgcat ggtttgatga
    18481 agggctttac tcagctcctg aagggtatac tttagaagat ttatttgcga cagtgaaata
    18541 ctatgttgaa catcctgacc aacgtcctca ctcagataat ggttggggta acgctagcga
    18601 ccatgttcgt aagcatcagg cagaccaaga cagtaaacct gatgaaaata aggaacatga
    18661 ggaagtaagt gagccaactc gccctgaatc tgatgaagaa gagaatcacg caggtttaaa
    18721 tccttcagca gataatcttt ataaaccaag cactgatacg gaagagacag aggaagaagc
    18781 tgaagatact acagaagaag ctgaagttcc tcaagtagag cgttctatta ttgaagttaa
    18841 gataacagag gcggaggctt tacttgcgaa agtaacagat tctcgtattc aacaaaatgc
    18901 tatggagaca ttggctggtc tacaaagcag tcttcttctc ggaacgaaag acaataacac
    18961 tattttagca gaagtagata gtctctttgc tttgttaaaa gaaagtaaac cgactcctat
    19021 acagtagtaa aatgaatgga gcatatttta tggagaagta acctttcgtg ttgcttctct
    19081 tttttagaaa aacgtaacag aaacttgaca aaagtaattt taaatagtaa accatttact
    19141 ggttaaataa ccggtttaga aaactattta atcaagtaaa agaagttgag aaaaagcttc
    19201 atcatttatt gaaatgaggg atttatgaaa atcaataaaa aatatctagc aggttcagtg
    19261 gcagtccttg ccctaagtgt ttgttcctat gaacttggtc gtcaccaagc tggtcaggct
    19321 aagaaagagt ctaatcgagt tgcttatata gatggtgatc aggctggtca aaaggcagaa
    19381 aatttgacac cagatgaagt cagtaagaaa gaggggatca acgcagaaca aattgttatc
    19441 aagattacgg ctcaaggtta tgtgacctca catggagacc attatcatta ctataatggc
    19501 aaggttcctt atgatgccat catcagtgaa gaacttctca tgaaagatcc gaattatcag
    19561 ttgaaggatt cagacattgt caatgaaatc aagggtggct atgtgattaa ggtagacgga
    19621 aaatactatg tttaccttaa agatgcggcc catgcggata atattcggac aaaagaagag
    19681 attaaacgtc agaaacagga acatagtagt aatcacggtg tcgattctaa cgataaggca
    19741 gtagttgctg ccagagctca aggacgttat acaacggatg atgggtatat cttcaatgca
    19801 tctgatatca ttgaggacac gggtgatgct tatattgtcc ctcacggcaa tcacttccac
    19861 tatattccta agtcgaatca aattggacaa ccgactcttc caaataatgg tctaacaaca
    19921 ccttcgccat ctcttccagt caatcctgat gtttcacatg aggaacatga agaagatggg
    19981 cacggctttg atgctaatcg tattattgct gaagatgaat caggatttat catgagtcac
    20041 ggtaatcata atcattactt cttcaagaag gacttgacag ctgatcaaat taaggctgcg
    20101 caggatcact tgaaaggtgg aatgcttgct acaccaactc cagcctatga tgatcacgat
    20161 caccatcaca gtgagggaca tgattccagc tttgatgcta atcgtattat
//
LOCUS       DAVDHZ010000038        19782 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000038 DAVDHZ010000000
VERSION     DAVDHZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.039"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..548
                     /locus_tag="VUR46_001675"
     CDS             <1..548
                     /locus_tag="VUR46_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5457064.1"
                     /translation="VKDGIIDGDRGKNYPKSDELFSEEYCLFLNTKNVTKNGFSFDTK
                     QFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRINSGMLILRPKTP
                     NLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQNEFADFVTLVDK
                     SQFACEIAIKVWRNSLKFSII"
     gene            578..3928
                     /locus_tag="VUR46_001676"
                     /pseudo
     CDS             578..3928
                     /locus_tag="VUR46_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            4199..4354
                     /locus_tag="VUR46_001677"
     CDS             4199..4354
                     /locus_tag="VUR46_001677"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457065.1"
                     /translation="MKIKEQTRKLAAGCSKHGFEVVDETDEVSNHTYGKATLTRIEEI
                     FEEYKSS"
     gene            complement(4471..4941)
                     /locus_tag="VUR46_001678"
     CDS             complement(4471..4941)
                     /locus_tag="VUR46_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5457066.1"
                     /translation="MNKSEHRHQLIRALVTKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4958..7231)
                     /locus_tag="VUR46_001679"
     CDS             complement(4958..7231)
                     /locus_tag="VUR46_001679"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET5457067.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFNLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSENELTADIFYTVAFQLLGFAYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEQPQLNLVQPQGQAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRRRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVIFTHGSQDWNVKPLHVYQIFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQAFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7577..10678
                     /locus_tag="VUR46_001680"
     CDS             7577..10678
                     /locus_tag="VUR46_001680"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET5457068.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRVAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKECQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRATGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10761..11768
                     /gene="pfkA"
                     /locus_tag="VUR46_001681"
     CDS             10761..11768
                     /gene="pfkA"
                     /locus_tag="VUR46_001681"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET5457069.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11827..13332
                     /gene="pyk"
                     /locus_tag="VUR46_001682"
     CDS             11827..13332
                     /gene="pyk"
                     /locus_tag="VUR46_001682"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET5457070.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(14017..14242)
                     /locus_tag="VUR46_001683"
                     /pseudo
     CDS             complement(14017..14242)
                     /locus_tag="VUR46_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            15090..15962
                     /locus_tag="VUR46_001684"
     CDS             15090..15962
                     /locus_tag="VUR46_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET5457071.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQYATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(16108..16452)
                     /locus_tag="VUR46_001685"
                     /pseudo
     CDS             complement(16108..16452)
                     /locus_tag="VUR46_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            16595..16906
                     /locus_tag="VUR46_001686"
     CDS             16595..16906
                     /locus_tag="VUR46_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457072.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETAEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKYSI
                     K"
     gene            16910..17626
                     /locus_tag="VUR46_001687"
     CDS             16910..17626
                     /locus_tag="VUR46_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5457073.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQVPKEIASLMNEWLAYFL"
     gene            complement(17755..18570)
                     /locus_tag="VUR46_001688"
     CDS             complement(17755..18570)
                     /locus_tag="VUR46_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET5457074.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKRVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHDNSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(18567..19472)
                     /locus_tag="VUR46_001689"
     CDS             complement(18567..19472)
                     /locus_tag="VUR46_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET5457075.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PEKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         6198 a         3392 c         4200 g         5992 t
ORIGIN      
        1 ctgtcaaaga tgggattata gatggtgata ggggcaaaaa ttatcctaaa tcagatgagt
       61 tgtttagtga ggagtactgt ttatttttaa atacaaagaa tgttactaaa aacggatttt
      121 cattcgatac aaagcaattt atcactaaaa caaaggataa attacttcga aaaggcaaac
      181 ttgagcgtta tgatatagtc ttgacaacaa gaggtactgt tggaaatgta gcgtactacg
      241 atgaattaat aaaatataaa catttacgta taaattcagg tatgctaata ttacgtccca
      301 agacaccaaa tctaaatcag aaatttatta tccatgtttt aaggaataat aattatagtc
      361 gagtgatatc aggaagtgct cagcctcagt taccaattac aaaattaaaa aaaatacttc
      421 tccccctccc cccactagcc ctccaaaatg agttcgcaga ctttgtaacc ctggtcgaca
      481 aatcacaatt tgcttgtgag atagctataa aagtgtggag aaatagcttg aaatttagta
      541 taatatagct aaactatttg tttaaagtga gaaaaaaatg ggaaatttta gctttctttt
      601 aaaaaatgac gaatatgaat ctttttcaaa accttgcatt gaagctgaaa atatgattgc
      661 tacatcaact gtggctactg cctttatggc gcgtcgtgct ttggagcagg ctgtccattg
      721 gatatatagt cacgattcat atttagaagc tccctatcgt gctactctat cttctttagt
      781 atgggatgat gattttaggg atatcgtaga ttctgaactc cacaagcaga tagttctgtt
      841 gattcggtgg ggaaaccatg ctgctcatgg tggtgaaatt aaggaacgag aagcgatttt
      901 agctttacat catttgtatc agtttgttaa ttttatcgat tattgttaca gcaatgaatt
      961 tgtggagcgt tattttaatg agaagtgctt accactttca gcaaacatca aataccgaga
     1021 aactccacaa tctatgataa agttacaaga cagtttacca gaactgcctg attttcatga
     1081 acagatggct gctcagtccg tagaagttca agagacttat actgaaaaac gtgagactgc
     1141 agcgcaacgg caagatgtgc ctttccatat tgaacaatta tctgaggcag agacaagaaa
     1201 gctctttatt gatatcgatc tccgtttagc aagatggata tttgaagaaa actgtcgtgt
     1261 tgagatagcc gttgatggtc tcaagcacgg ttcaggaatt ggttactgtg actatgtact
     1321 ttatggtaaa aatgggaaaa ttttagcgat tgtagaggct aaaaaagcct ctgtcaatcc
     1381 agaagtaggg gaagtacagg tcaaagaata tgctgaagct cttgagaaac atatcggcta
     1441 tcagccaatt tgctttatta caaatgggtt gaagcactat atacttgatg gtccgaaccg
     1501 acgccagatt gcaggctttt actctcaaga agaattgcaa ttagtgatgg atagacgtca
     1561 tcttcaaaaa ccacttgagg atatttctag taaaattaga gacgatattt ccgggcgtta
     1621 ctaccaaaaa catgcgattg caagcgtttg agaagctttc tctgatcatc gtagacaggc
     1681 acttttggtt atggcaactg gggctgggaa aactcgtaca gcagtttctc tagttgatat
     1741 cttatcacgt cataactggg taaaaaacgt tctcttctta gccgatagaa cttccttggt
     1801 taagcaagta tatgattcgt ttagaaaatt actcccagat ctttccgttt gtaacttctt
     1861 agaagataaa gaaggagctc aatcaagtcg catggtcttt tcaacttatc cgaccatgat
     1921 tggagcgatt agtggtcaag aagaagtaaa tcaacgccct ttcactgttg ggcattttga
     1981 ccttatcata attgacgaat ctcaccgttc tatttatcag aaatacaagt ccatttttga
     2041 ttattttgat gcaagaattg taggcttaac agctactccg cgtcaagatt tagataaaaa
     2101 cacctatgga ttctttaatt tggagaatgg ggttccaaca tatgcatatg atttggaaga
     2161 ggctgttaaa gacggatatt tagtagccta tcattctatc gaaaccaaac tgaaactacc
     2221 tacggatggt ctacattatg atgatttgtc cgaagaagaa aaggaacatt ttgatagcaa
     2281 atttgaagac gatatctgtg aaaaagatat tgatgggagt gtatttaatt cctttatttt
     2341 caataaaagt acagtagaaa ttgttttaaa tgaactcatg acaagaggaa ttcagacagc
     2401 ctcgggtgat gaaattggta aaactattat ttttgctaaa aatcatgatc atgcggaata
     2461 tatcagaggt atttttaaca accgctatcc tgaaaaaggg agcgactatg ctcaggtgat
     2521 tgattatagt attaagcatt atcagacctt gattgatgat tttaaaatta aggagaagta
     2581 tcctcaaatt gcgatttctg tcgatatgtt agatacaggt attgatgtat cagaggttgt
     2641 taatttagtc ttcttcaaga aagtacgctc taaaactaag ttttggcaga tgattggtcg
     2701 aggaacccgt ctatgtaaag atttatttgg acctgagcag gataaggaaa acttcttggt
     2761 atttgattat ggggacaatt ttgattattt tcgtgcagat ccaagagatg gagagggtcg
     2821 tcacattgtt tcgttgactc agcgtttatt taatatcaaa gtggacttga ttcgagaact
     2881 tcagggactc caataccaag aagatcagtt tgcgagagca taccgtcagc agcttgtctc
     2941 ggaacttcaa ggtcgtatag agagcttaaa tgagttggac ttcagggttc gtatggtttt
     3001 aggtacagtt tatagctata ggaaattgga aagttggcag aatctaactg ctgttacaag
     3061 tgaaaccatt caaaaaaatc tctctccgct tttatttgat gaagataaag aagatgagat
     3121 ggcgaggaga tttgatttgt ggttgcttca tattcagttg gggcaactga cagctaaatc
     3181 ttccactgtt catatttccc aagtgatgaa gacggctaga gctctttctg ctattggcaa
     3241 tatcccgcag gtttttgagc aggctgaaat tatcaggaaa gtacaggagc ctgaattttg
     3301 gaaagaagtt aacttgtctg atttggaaaa aattcgtctt gctattcgag atttattaca
     3361 gtttttggat aaaacagacc gtaaactcta ctatattaac tttgaagatc gtatactctc
     3421 cactgttcac gagaccacag catttttgca ggtcaacgat cttcggtctt acaatgaaaa
     3481 agttgagcat tatttgaaaa ctcatctgga tgaggagtcc atttctaagc tataccataa
     3541 taaaaagttg acatctgatg atatgcttgc acttgaaaaa ttgctctggg aaaaattagg
     3601 tagtaaagca gactaccaaa gtcattatga aaataaggca attccgagat tggttcgtga
     3661 gattattggc ttagatagag agtctgccaa tcgtattttt tctaaatttt tgtcggatga
     3721 gaatcttaat gccaggcaga tttcatttgt aaaattgatt gtagactaca ttgtagaaaa
     3781 tggtttttta gagacgaaag tgttaacgca agagccgttt aaatcttatg gttctgttca
     3841 actactcttc caacaccaac taccagtact tcgtaatatt gttcaaatca ttgaacttat
     3901 caataatcga gctggagaag cggcttaaat tctaaagtga ttgccatgct gagactcatt
     3961 taaaattaaa aagagtagaa atttatgcta tatatgagaa gttttattag gaagaatgtc
     4021 atcgttttcc tagaatacag tatcagttgt taagtggttg ataaatttca aagtagatac
     4081 ttgtaccacg atgtttgttg atcgagttat taacaaaaga gctactttga ttttaaagaa
     4141 atagaaaaca aaaagccgag caagaattca attgcaggag aaaatgaaat aatactcaat
     4201 gaaaatcaaa gagcaaacta ggaaactagc tgcaggctgc tcaaaacatg gttttgaggt
     4261 tgtagatgaa actgacgaag tcagtaacca tacctacggc aaggcgacgt tgacgcggat
     4321 tgaagagatt ttcgaagagt ataaatcttc ctaggataaa gcaaaacgca tagtatcaag
     4381 ggttttcaac acttgatact atgcgttttc tgatgttaaa gactttctac caggtttttt
     4441 aaaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg gtggggcgaa
     4501 ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga tgataagaca
     4561 gacatcatta ccacaaaggg tagcgatagc gtcagggaag ctcaaagtat caatgataga
     4621 accgaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt gaactgggcg
     4681 catccagaca agggcatctt ccatgtagag ttcgagacgt ttttcccatt ttgagatgga
     4741 accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata ggttcatatt
     4801 tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg tcgttctcag caagaagggc
     4861 ttgcaactca gcctgtgtat gaatcttgtt ttttgtgaca agagcgcgta taagttggtg
     4921 gcggtgttct gatttattca taataatgta attcctttta gcaaggtaag gtaagcatgg
     4981 actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg atttcaaagt
     5041 cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa atagttggct
     5101 gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact aacagtaaat
     5161 catttctatt ttgtaaatta aggtaacctt ttgtcacgac tcgttgtgcc tctggtctaa
     5221 atggcaattc acagagattt tccaacatgt gatagcgacc gttgtcaatg gttctagcac
     5281 ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc agttgggcag
     5341 ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg cgaccgttta
     5401 ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attagctttc ccttgataga
     5461 gctctgtatt gaaggcttgg tatgtcttac catagcgctc aaaatcctta tctgggtact
     5521 ggttttgaat agcttgctct tcttgaccaa gtgagaaggt ttcacagttt tcttgcccac
     5581 cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag ataacagtag
     5641 gaagttgaaa gtctgtttcc tgtcctagta atttcttggt taataaggca tttatggact
     5701 cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta tggaaaaaga
     5761 gatgcttgtg tatatgagta ggaagagcat ggaagatctg gtaaacatga agtggtttga
     5821 cattccaatc ctgagaacca tgagtaaaga taacctctgc ctttacttta tgggcattga
     5881 gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg tctagctgag
     5941 ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag tcgccagcta
     6001 agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct ggataaccac
     6061 ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa attcctgcct
     6121 cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg gacatggtac
     6181 ctagatagga aagtcctgtt gtagcaactt ttccgtttga ccaatcagcc ttgacttgac
     6241 gctggcgcgt gtgatcagta aaggcacggc gacggccgtt aagccaatcg atgacatttt
     6301 tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag tctttggtac
     6361 caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg tttagtgtat
     6421 agctagagtt gatgtgagtt agcttttcct cagcctctgc tacaagctca gcttgacctt
     6481 ggggttggac gagatttagt tgaggttgct ctagctcaat cttgtgagga agcttaacct
     6541 caagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg gttccctgat
     6601 gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg cgaataatgc
     6661 taacctttac taggtctggt agcccttttt ggtcagtatc gacacgagac tcaacgtaaa
     6721 cgacttcacg aatgacatcc tggctagaaa aagtagccaa actcttgccg ttaaagtagt
     6781 ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata agagtatttc
     6841 cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca ccatatataa
     6901 tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc aaataagcaa
     6961 agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca ttttccgatt
     7021 gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatggaaagt gggtagttgg
     7081 tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct ttgtgattgg
     7141 ctgtattttg taaattaaag ccacattttt ttagttcaga taagacattt tcttttggaa
     7201 aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg acagttaagg
     7261 ttattatatc aaaaaaaaag cagaaaggga attgttaact tcaaaaggaa ataatccaat
     7321 aaaaatgaat aaagtactaa attcaatata gagaacagag taacaataag aataatagat
     7381 agggtataaa agttctagga gatttatatt atatgctttc tgtttttata tacaatatag
     7441 tataaatata aaaacgatga caaaaataca aatgaataga aaataaatta gtaagctgat
     7501 gaaatttttc tcaagagaag ccatttatag gtgaaaatgg tataatatag tgagaaggat
     7561 agaggagaag tgtaaattga tcgcacaact agatacaaaa acagtctata gttttatgga
     7621 aagcgtcatt tcgatcgaaa agtatgtgag agtagctaaa gaatacggct acactcattt
     7681 ggctatgatg gatattgaca atctttatgg cgctttcgac tttctagaga ttacaaaaaa
     7741 atacggcatt catcctttgc tagggcttga aatgacagtg tttgtagatg atcaggaagt
     7801 gaatttgcgc tttttagctc tatctagtgt gggctatcag cagttgatga agctttcgac
     7861 agccaagatg cagggggaga aaacttggtc agtcctgtcc cagtacctgg aagatatcgc
     7921 ggtcattgtg ccttattttg atagagttga gtcgttagaa ctaggctgtg attactatat
     7981 aggggtttat ccagaaacac tagcaagcga atttcatcat cctatcttac ctctttatcg
     8041 ggtcaacgct tttgaaagca gggatagaga agttcttcaa gttttaacag cgattaaaga
     8101 aaatctaccg ctcagagaag ttcccttgcg ttcgagacaa gatgtcttta tatcagcaag
     8161 ttctttagag aaactattcc aagagcgttt tccgcaagct ttggacaatt tagaaaagct
     8221 tatttcaggc atttcttacg acttggatac tagtctgaaa ctgcctcgtt ttaatccagc
     8281 tagaccagca gtagaggagt tgagagagcg tgctgaactg gggcttgttc agaaggggtt
     8341 gactagtaaa gaatgtcaag atagactaga ccaagaattg tctgttattc atgatatggg
     8401 ctttgatgat tatttcttgg ttgtttggga tttgttgcgt tttggacgat cgaatggcta
     8461 ttatatggga atgggaaggg gttctgcagt aggcagtttg gtttcttatg ccttagacat
     8521 cacggggatt gacccagtag agaaaaatct gatttttgaa cgctttctta atcgtgaacg
     8581 ctataccatg cctgatattg atattgatat cccagatatt tatcgtccag attttatcag
     8641 atatgttggt aataaatatg gtagtaaaca tgcggcacaa atcgttactt tttcaacctt
     8701 tggagccaag caagctcttc gagatgtctt gaaacgcttt ggtgtgccag agtatgaatt
     8761 atctgcaatt actaagaaaa tcagttttcg tgacaatctt aagtcagcct atgagggcaa
     8821 tctccagttt cgtcagcaaa tcaatagtaa gttagaatac caaaaagctt ttgagattgc
     8881 ttgcaagata gagggctatc caaggcaaac ctctgtccat gcggctggtg ttgtaattag
     8941 tgaccaagat ttaaccaact acattcctct aaagtatggt gatgaaattc cactgactca
     9001 gtatgatgct catggagttg aggctagcgg acttttgaag atggactttc tgggactacg
     9061 aaatttgacc tttgtccaga agatgcaaga gttgcttgct gaaacagaag gtattcatct
     9121 gaaaattgaa gaaatcgatt tagaagacaa agaaacgtta gctttatttg cctctggtaa
     9181 tacaaaaggt atctttcaat ttgagcaacc aggtgccatt cgtctgctta agcgtgtgca
     9241 accagtctgt tttgaagatg tcgtcgcgac tacttctcta aatcgaccgg gtgctagtga
     9301 ctatatcaat aattttgtgg caagaaagca tgggcaggaa gaagtgactg ttctggatcc
     9361 agtactggag gatattttgg ctccaaccta cggcatcatg ctctatcagg agcaggttat
     9421 gcaggttgcc cagcgacttg ccggatttag tcttgggaaa gccgatattt tgcgtcgggc
     9481 gacggggaaa aaggatgcct ctgccatgca tgagatgagg gcttccttta ttcaaggttc
     9541 attagaagct ggtcatactg tggaaaaagc agagcaggtc tttgatgtta tggagaagtt
     9601 tgcaggttat ggttttaaca ggtcacacgc ctatgcctac tcagccttgg ccttccagtt
     9661 ggcttatttc aaaacgcatt atccagccat tttttatcag gtcatgttaa attcttccaa
     9721 cagtgattac ttaatagatg cacttgaagc aggttttgaa gtagcctctc tatccatcaa
     9781 caccattccc tatcacgata aaattgccaa caaggccatc tatctaggtt tgaaatccat
     9841 taaaggagtc agtaatgatt tagctctctg gattattgaa aatagacctt attctaacat
     9901 tgaagatttt atagctaaat tacctgagaa ttatctgaaa cttcctctgc tagaaccttt
     9961 ggtaaaagtt ggtcttttcg attcatttga aaaaaatcgt caaaaagtat ttaataactt
    10021 agctaatcta tttgaatttg tgaaagagtt gggaagtttg tttggagatg ctatttatag
    10081 ttggcaggaa tcggaagatt ggacggaaca agaaaaattt tatatggaac aagagctttt
    10141 agggataggt gtcagcaaac atccactaca agctattgca agtaaggcta tttacccgat
    10201 taccccaatc ggaaatttgt cagaaaatag ctatgctatt atcttggttg aagttcagaa
    10261 aataaaagtg attcgtacca aaaagggtga aaatatggcc ttcttacagg cagatgatag
    10321 taagaaaaaa ttggatgtca ctctcttttc agacttatat cgtcaggttg gacaggaaat
    10381 aaaagaggga gccttctact atgtaaaagg aaaaatacaa tcacgtgatg gccgtctgca
    10441 aatgattgca caagaaataa gagaagcagt tgctgaacgc ttttggatac aggtgaaaaa
    10501 tcatgaatcg gatcaagaaa tttcacgcat tttagaacaa tttaaaggcc caatcccagt
    10561 catcatccgg tatgaagagg aacagaaaac catcgtttct ccccatcatt ttgtagctaa
    10621 atccaatgaa ttagaggaga aattgaatga aatcgttatg aaaacgattt atcgctaaaa
    10681 atacggaaaa tagaagaatt ttaaaatcaa atgtgatata atcaagaaga atgttaaaag
    10741 aaaaaggagc ataaaccaat atgaaacgta ttgctgtttt gactagtggc ggagacgcac
    10801 ctggtatgaa cgctgccatc cgtgcagttg ttcgtcaagc aatttcagaa ggaatggaag
    10861 tgtttggtat ctatgacgga tatgctggta tggttgccgg tgaaattcat cccctagatg
    10921 cagcttcagt aggagacatc atttctcgtg gtggtacttt tcttcactca gctcgttatc
    10981 cagagtttgc tcaacttgaa gggcaactta aagggattga gcaattgaaa aaacacggaa
    11041 ttgaaggtgt agttgttatc ggtggtgacg gatcttacca cggcgctatg cgtttgactg
    11101 aacatggctt cccagctatt ggtcttccag gtacaatcga taacgatatc gttggtactg
    11161 actttacaat cggttttgac acagcggtta ctactgccat ggacgctatc gataagattc
    11221 gtgatacatc atcaagtcac cgtcgtactt ttgtaatcga agttatggga cgtaacgctg
    11281 gtgatatcgc tctttgggct ggtattgcaa ctggtgctga tgaaatcatc atccctgaag
    11341 caggcttcaa gatggaagat atcgtagcaa gcatcaaagc tggttatgaa tgtggtaaaa
    11401 aacacaatat catcgtctta gctgaaggtg tgatgtcagc ggctgaattt ggtcaaaaac
    11461 ttaaagaagc tggagataca agcgaccttc gtgtaacaga acttggacat attcaacgtg
    11521 gtggttctcc aactgcgcgt gaccgtgttt tggcgtcacg tatgggtgca catgctgtta
    11581 aacttcttaa agaaggtatc ggtggtgttg cggttggtat tcgtaacgaa aaaatggttg
    11641 aaaatccaat tcttggtact gcagaagaag gggcattgtt tagccttact gcagaaggta
    11701 agattgtggt taacaaccca cacaaagccg atattgagct atctagcttg aataagagct
    11761 tgtcataatt tacaatttag ttaataagac caaaaaggtc atatatataa aggagtcaca
    11821 aaaatcatga acaaacgtgt aaaaatcgtt gcaactttgg gtcctgcggt agaaatccgt
    11881 ggtggtaaaa aattcggtga ggacggatac tggggtgaaa aacttgatgt tgaagcttca
    11941 gctaaaaaca ttgctaaatt gattgaagct ggtgctaaca cattccgatt caacttctca
    12001 cacggcgacc accaagaaca aggtgagcgt atggcaactg ttaaacttgc ggaaaaaatt
    12061 gcaggtaaaa aagttggttt ccttcttgat acaaaaggac ctgaaatccg tacagaattg
    12121 ttcgaaggtg aagctaaaga atattcatac aaaactggtg aaaaaattcg tgttgcaact
    12181 aaacaaggaa tcaaatcaac tcgtgaagtg attgcgttga acgttgctgg tgctcttgat
    12241 atctatgatg atgttgaagt tggtcgtcaa gttttggttg acgatggtaa acttggtctt
    12301 cgtgtggttg ctaaagatga tgcaactcgt gaatttgaag ttgaagttga aaacgatggt
    12361 atcatcgcta aacaaaaagg tgtgaacatc cctaacacta aaattccttt cccagctctt
    12421 gctgaacgcg ataacgacga tatccgtttc ggtcttgaac aaggtatcaa cttcatcgca
    12481 atttcattcg tacgtactgc aaaagatgtg aacgaagttc gtgcaatctg tgaagaaact
    12541 ggaaacggac atgttcaatt gttcgctaaa atcgaaaacc aacaaggtat cgataactta
    12601 gacgaaatca tcgaagcagc tgatggtatt atgattgctc gtggtgatat gggtatcgaa
    12661 gtaccgttcg aaatggttcc agtttatcaa aaaatgatta tcaagaaagt caatgctgca
    12721 ggtaaagttg ttatcactgc aacaaacatg cttgaaacaa tgactgaaaa accacgtgca
    12781 actcgttcag aagtatcaga cgtattcaac gctgttatcg acggaactga cgctacaatg
    12841 ctgtcaggcg agtctgcaaa cggtaaatac ccactcgagt cagtaactac aatggctaca
    12901 atcgacaaga acgctcaagc tcttcttaat gaatacggac gtcttgattc agattcattt
    12961 gagcgtaact ctaagacaga agtaatggct tctgctgtta aagatgctac taactcaatg
    13021 gatatcaaat tggttgtaac tcttactaag acaggtcata ctgcacgttt gatttctaaa
    13081 taccgtccaa atgctgacat cttagcattg acatttgacg aattgacaga acgtggcttg
    13141 atgttgaact ggggtgttat cccaatgttg acagatgctc catcttcaac tgacgatatg
    13201 ttcgaaatcg ctgaacgtaa agcggtagaa gcaggtctcg ttgagtcagg cgatgatatc
    13261 gttatcgttg ctggtgtgcc agtaggagaa gctgttcgca caaacacaat gcgtatccgc
    13321 acagtacgtt aagaaaaata taaaaaccta tcatatccag ctttagagct tgtgtgatag
    13381 gctttttgta tagagggtaa gaaagaggca aaactttcat aatggattga tactcttcga
    13441 aaatcaaatt caaaccacgt cagcgtcgcc ttaccttact caagtacagc ttgcggctag
    13501 cttcctagtt tgctctttga ttttcattga gtatgaaata agatatgcac aaattgatta
    13561 gaaagtcaaa tgaatttcta caaatgtttt agcaatcgta atgtacttgt ctagattcga
    13621 tctgatatat tttcgattta atgatatggt atttaaaacc tccaaagtag cttgctccat
    13681 tcttttactt acgtgagtgt agatgttatt tactgtttta gcgtttttgt gttccactct
    13741 aaccattata gcattcttct cagctagtgt actaaggagt gtgtgcctga aaatatggga
    13801 actaaggggc tggtttatcg gtttctctag tttagtattt gccttttgca aagtgatctt
    13861 aaatgccttt ctctaaattt acatatcact attgtttaac aaaatctaat ctactttagg
    13921 tcacttattc tttttttgaa atgtagaatg aactttttca aagtttttcg aatcttttaa
    13981 aatctgtttg ttttatatcg ccattctccc ccttttttaa ttctccctat atagcctgac
    14041 aactttcccg atggtacgaa tatggttgct ttcgtctagg tggatgtcgg ggtatttggg
    14101 attgagtttt tttaaggtag ccttggcgga gtttcttgac atagttagcg ccgtctactt
    14161 ggaagatgcc gatggtatta tagtcaatct gtggggtatt cttgataaat aggtagtcgc
    14221 tgtttcttat ctttggctcc atggacttgc tgacgacata agcgattggg tcgtagtcgt
    14281 ctgggataat ggaaactcca tatctaaatc gttgtcctgc atcgagcggc tacctgcaga
    14341 gataaactac ctaacacgag agtaagtagt ctgtctgtag tcgtccagtc tgatgatttt
    14401 tacgatactt cgtttttctg ctcatacagt tgcctctagg cataggttag gactttacct
    14461 tgtctgggtg gtgcccgttg gtcgtagata gattggatat cgctaggaga atccttttga
    14521 actggaggaa agagggcatc gatcaagcta ctgaatactt taactaagtc aaatatagta
    14581 tttttcttag tagacctaac ccttttttca taatttctaa tggtgttttt acttatacct
    14641 atcttagtac ccaattctta ttgagtccaa ccattactag tctatattgt tttatagttg
    14701 attgagtttg gaatagtacg ctgtagctgc taaaacattt ctaggaatta atttgccttt
    14761 cctaatagag ttgttcatat cttatttcaa tctactatat ttttcacctc taacaatcgc
    14821 aatctcttct ttatccatga atgaaatcgc tttctgtttt tgtaagtaaa gcataacacg
    14881 aaatccacga aaatgaaaac ctttgttgtg ttttcgtaaa aaatttgttg acagagcacg
    14941 aaacgtctac tataattaaa tcaagcttaa ggaaataaca aaaaaacaaa tcggagggaa
    15001 agacgatgaa cacattaaat gagaaagtaa tcaatatctg taaagcagta gttaaagaaa
    15061 ctttaatcca agacatttag gagaaagaaa tgaagaaatc aagaaaatta gccacattag
    15121 gaatctgttc agctttgttt ttaggcttgg ctgcttgtca acaacaatat gctacttctg
    15181 aggggacgaa tcaaaggcaa agcagttcag cgaaagttcc atggaaagct tcatacacca
    15241 acctaaacaa ccaggtaagt acagaagagg tcaaatctct cttatcagct cacttggatc
    15301 caaatagtgt tgatgcattt tttaatctcg ttaatgacta taataccatt gtcggctcaa
    15361 ctggcttatc aggagatttc acttccttta ctcacaccga atacgatgtt gagaaaatca
    15421 gtcatctctg gaatcaaaag aagggcgatt tcgttgggac caactgccgt atcaatagtt
    15481 attgtctttt gaaaaattca gtcaccattc caaagcttga aaagaatgac cagttgcttt
    15541 tcctagataa tgatgcaatt gataaaggaa aggtctttga ttcacaagat aaggaagagt
    15601 ttgatattct attttcgaga gttccaactg aggcaactac agatgtcaag gttcacgctg
    15661 aaaagatgga aacattcttc tcacaatttc aattcaatga aaaagctcga atgctgtctg
    15721 tagtcttgca cgacaatctg gatggcgagt atctgtttgt aggccacgtt ggggtcttag
    15781 tacctgctga tgacggtttc ttatttgtag agaaattgac tttcgaagag ccctaccaag
    15841 cgattaaatt tgctagtaag gaagattgct acaagtattt gggcaccaag tatgcggatt
    15901 atacaggcga gggactggct aagcctttta tcatggataa tgataagtgg gttaaacttt
    15961 aatagtgtta tgatatgaca gtaatcttag gatttttatt tctatttttg atgagttggt
    16021 gggttatttc aatcgttaat agccagaaac cacgcaaaaa tgaaacattt attggctata
    16081 tccaaagata cgatattgat gggaatggct atcaatcatt accgtgtcct cagaactgag
    16141 aggagttctt gaaaccgtaa aaccgctttg aacaagagtt acttcaaccc attggctccg
    16201 acggagtaag ttgctttcgt gaataccaaa atcagccgca atttcttcat aagttcgata
    16261 ttctcgcaca tattgaagag tggccataag aaggtcttct aggcttaatt taggttttcg
    16321 tccccctttt gcgtgtttaa gttgataagc tgtttttaat acagctaaga tctcttcaaa
    16381 agtggtacgc tgaacaccaa caagacattt aaatcgtgca tcagttagtt gtttacttgc
    16441 ttcataattc atagaactac tataccatat tttgtttcgc aggaagtcta atgctaaaat
    16501 cttatcagtg agaagatttc ttaaagttta ttctttgtag tttcatctgt attagtacat
    16561 aatttaacct agagaaaata ggaggactaa tcgaatggaa ttaaaagatt ttacagaaaa
    16621 agaacaggaa atgattaaga aaaggcttac aatgtctaat attagtgaca aagaaactgc
    16681 tgagaagatt ctggcgctag taccacaaga cttgattaag cgaatcccgt tttttgtcag
    16741 aaaacatgct acaacacgta cgattaaacg catttcaatt gaacaccctg aactctacgc
    16801 tgtagctcaa acaagtggtg agattccaga aaaagaacgc gaagaattgc gtcagattat
    16861 cacaactatc tttgaacaaa agatgaataa gtatagtatt aagtagagaa tgaaaaaata
    16921 ttttattggc ggtttgggaa gcaatgccta tcatagcaag gattttcttc aagaactaga
    16981 ttcgcaggtc tattttctaa atccatatga aaagcatctt cgagatgaaa cagaattgaa
    17041 atcatggttt aaaaatgaga ttgtagagga ggaatctatc tgtctgatag gtcattctct
    17101 tggaggagat ttagctcgtt atttcgcatc ggaatttgaa gaagtaaaga aactgattct
    17161 tttggatggt ggctatctag atttagataa gattttacct ttggatacag agttagagga
    17221 aactaaaaat tatatcaaat ctcaaattat ttcggactta gctcttctta tttctaaaga
    17281 aaaatctgaa gcaaagcatt ggtcagaaaa tatggagaaa gccgtaagac agtcctatca
    17341 ctggaatgtt gagtataata gatatgagtt ggctataaat tatgaaaata tagaagcgat
    17401 actccgccta cggagaaaaa tacaagcttt taagagagaa gtgggagata ccttgtttat
    17461 tagtcctcgc tatcctaatg aagctacatg gagagaggaa gccctaaaag aattgccaga
    17521 ctattttgat actatttttt tagaaaactt tggccatgag ctttatactc aagtgcctaa
    17581 agaaatcgct agtctaatga atgagtggct cgcttatttt ctatgagcta cttgtattgc
    17641 tggaaatggt ataagatgaa aatctacaag tcactaattt tcatataaca aaaaacgaac
    17701 aggctctttt tctgttattc agaagagaac ttgttcgttt ttatcttgat tttcttaaaa
    17761 agctctatat acatagggat tttctggttt atcgactttg gtaaagctgt cgatttccaa
    17821 ggttggaagg ttttgtttga gttctttatg gtagtgattg accagttttc ctttggctga
    17881 aatccaagtg ttgttttcat actgccgggt attgcccttg gtcagcaatc catagacacc
    17941 agaatctgcg atacagtgga taatgccgaa gcggaacaga aattggctat tgtcatgact
    18001 ggggtcgtta tagacaaagc ctgtaaactg gattgtcttg ccctcaaact catctggata
    18061 gtcgtagata gcctccatga cttccatata gttttcatta gtgatctgaa tactatcttg
    18121 ggataagtat ttatccgccg ccgttcgcat ttccttttca taggctgatt ttgaaaaata
    18181 agaactggta tctggtttca aatattggct tgtcgtccct tcgcttgtct gaatggctag
    18241 atccgttcct tctgataggg ggaaatgata acctttagca gaaacggtct gagaatccaa
    18301 gctaacagtt gggaaagtta agccgatgac aagtggaata gccagaagag aaatactcgt
    18361 catcttggcc aatcggctgt tcagatgact gtgggttttg actcgcttca tccagatata
    18421 caattgaacg atagccaaga taaaagaaag taccatggaa atataggcta gataggaata
    18481 gtgcatgttg atgtactggt ttagtttgcc cgacagatgg aggtaaatag tcagttcaaa
    18541 atagccagct aaaactaaaa atcgaatcat aggatgactc caatcaagag agaatagact
    18601 aagacgacaa gagttacaat cgttatgaag tgactgataa atcgtgcttt caagtaattt
    18661 ttcatcatga gaatattttt gatatccagc attggaccaa tgacgagaaa ggccagaact
    18721 ggtgccaaac cgaaactcga gagaagagaa gcacctataa aggcatccgc ctcactacag
    18781 agcgaaagaa gaaaggccaa aatcatcaag agcaggatgg caaaaagagg ggttgcactg
    18841 atagaggtca gaatccgagt cggaacgtag acctgtatta tagaagcaaa gaggcaacca
    18901 aataccaaat aacgccccgt atcaaaaaat tcatcaatgg cctgcacaaa gacttgaaaa
    18961 actttttttg cagaactcaa gtaagaaaaa tcatgctcat gacaagccag acgattttct
    19021 ttctgaatcg gttcttgcca gaaaaatcct agaaaaattc ctagtattac agccacaaga
    19081 atggaaccca gagctcgtaa tagggcgaca tggaaggagt tgccaaaggc agaataggtc
    19141 gcaaaaagaa caatgggatt gataacaggt gctgtcacaa gaaaaggaac ggccgtgtaa
    19201 cttggaacct ttttttccag aaaacgattg ataatgggga cgattccaca ttcacaagaa
    19261 gggaaaagca taccgacgaa ggtcccaaaa aagattcttc cccaacgatt tcgagggaga
    19321 aaatgataaa ccttttcagg tgtgatataa acctcaatca gccctgagac aatgcttcct
    19381 atcagaacga agggaagggc ttcaatgata atggagagaa aaatggctcc agtttgaagt
    19441 acactagatg ggagttgttg aaaagcagtc atctagtttt tcttttctgc tttggctttt
    19501 ttctctttgt catcagggaa agtaacttgt ttcaaatcag ggagtttagc aaactcttca
    19561 aacatcttgt ccaagtcgtc tcgttttgta aattttacag ccataggtgt acctcgattc
    19621 taaatcctac ctctattata ctattatttt gcggaaaagg aagtttttta atttgttttc
    19681 gatagttgat actcttcgaa aatctcttca aaccacgtca gcttcgcctt tccgtagtac
    19741 ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca gt
//
LOCUS       DAVDHZ010000039        19164 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000039 DAVDHZ010000000
VERSION     DAVDHZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.040"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..241
                     /locus_tag="VUR46_001690"
     CDS             <1..241
                     /locus_tag="VUR46_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="toxin PezT"
                     /protein_id="HET5457076.1"
                     /translation="VNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSGEDTTSAATVL
                     HDLLFGEWNTVEKEMLKIGQERLWVINKELNNRGD"
     gene            243..1639
                     /locus_tag="VUR46_001691"
                     /pseudo
     CDS             243..1639
                     /locus_tag="VUR46_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1641..2336
                     /locus_tag="VUR46_001692"
     CDS             1641..2336
                     /locus_tag="VUR46_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457077.1"
                     /translation="MRDIVIKFLQNNHFNQLDTDFDFYTNSQKSEYFIVSQYSPDELN
                     NFFDDDKTSQVIKEFERVSLTPEHENIKKNTSMFILVEVDDLKEVFEDEKVQRSILLI
                     EEDYYYFRKFIILYTRNGLLDLRDKETNEILYTYLESNIDAFEDDMFFSESYFMAMEI
                     GVKLPFFTLPKRNDIYQSIESQYQDDKDELDNRLLDFYTKNTDEKLSKSLKDISTDDD
                     NISDLLQIGELLQ"
     gene            2333..4981
                     /locus_tag="VUR46_001693"
     CDS             2333..4981
                     /locus_tag="VUR46_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5457078.1"
                     /translation="MKIKKILIKNFKNIKETRIIDFQENVTLFVGPNGFGKTTIFDAI
                     ELSLTGKIRRIEESDYSDGRSSFSAPYFQNNPNQNTFIELMLTNDEGNSLIVSSLYKS
                     SMNTEGSNVPKFSFSKFQRRVRVGPGISFQSDEDFEGSSERDIQKDISQFLGYESEDY
                     SLGDTFDLFHYIQQDETAYYLKQKEKDRKEQLNFLLNIGNYVNRKNRLERLRSTLSSS
                     EKELRAKKGKLKNSPIKNNILYSKLSLRADTDFAFNNKSIIFDEELSNESLNIYLSEI
                     TKLQEFRNSFSPKDYFLRKQSEQFEREVLDDKDFTIYLIVREILENQENIESIKQNYS
                     LISNEKNFSYFLLKNYLERQDLLENDSKLFKFGKRLKSLLDVEIAKIDIKSIENSLNN
                     FTGWEFGRLWIEKFEPKLTEYKFKEGQLDDGTESINKLLEIRTRLKEHSTGNHSECIF
                     CGYDWGESENLLAAYEETTNQLRKNLTNFEIEVSNLVEELNQLKMELQNQIQMEQEKL
                     FVIPDDFLAAIRSISNYNFPESFSNLVVMNSEITPLPVDKSASLQEFENLKTELISSL
                     QEKLLIPNEVYGTFLRVVNKSVDFEKLLEKYSILAGESIREYEISFDLLPISLHKFEE
                     NKDRLLVFLGDLRSQIVFDYSKSLDSQNLFDKYFASKEKTFEDCTIESINQKREYIIN
                     QFELQSLTMFHQIEKRLQIIEQTITYLQDRVRELNNNIKSYQEQMIQKLKLPFYMYTA
                     KILQNYQQGMGVLLTTQNNSNIRFIANSNSEQDVMYQLSSGQVAVISFAFTLALNTTF
                     KISRGFKFLSIDDPIQDMDSMNVYALIDLIRHSLSDYQIIMSTHNDGSAMFIKYKFEL
                     FSDSEISNVGLKNIKNILLLDVEVSS"
     gene            5370..5729
                     /locus_tag="VUR46_001694"
     CDS             5370..5729
                     /locus_tag="VUR46_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457079.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            5739..6104
                     /locus_tag="VUR46_001695"
     CDS             5739..6104
                     /locus_tag="VUR46_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HET5457080.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERISKSNCQNFSVYARKVLLS
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLNEFHGSY"
     gene            6091..7957
                     /locus_tag="VUR46_001696"
                     /pseudo
     CDS             6091..7957
                     /locus_tag="VUR46_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(8002..8856)
                     /locus_tag="VUR46_001697"
     CDS             complement(8002..8856)
                     /locus_tag="VUR46_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HET5457081.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDGFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLVNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIGKEEFSNCSYLISKIK
                     TLLDNKLNFYEQPVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     FNKLVNKK"
     gene            8936..8998
                     /locus_tag="VUR46_001698"
     CDS             8936..8998
                     /locus_tag="VUR46_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET5457082.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            9079..9621
                     /locus_tag="VUR46_001699"
     CDS             9079..9621
                     /locus_tag="VUR46_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457083.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIENVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDLYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELKRT"
     gene            9618..10757
                     /locus_tag="VUR46_001700"
     CDS             9618..10757
                     /locus_tag="VUR46_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5457084.1"
                     /translation="MMTRKVPNIEQMSQIECGFCCYLSILHFYKSKETLLDLRRDIEK
                     GRDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNK
                     VYIMDPSKGYVNYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKG
                     RLILTLLFSIISYLIILSIPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILAR
                     SMGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVV
                     GGVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSL
                     IYSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSVE"
     gene            10820..11461
                     /locus_tag="VUR46_001701"
     CDS             10820..11461
                     /locus_tag="VUR46_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5457085.1"
                     /translation="MTIESGQRIALVGQSGSGKSTLLKILLGLYKIDTGKVLFDGINI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTKIIVSHRLSTIKDADIIFVMKGGKIVESGNHKYLMALGGEYYSLYTKRK"
     gene            11474..11644
                     /locus_tag="VUR46_001702"
     CDS             11474..11644
                     /locus_tag="VUR46_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457086.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            11678..12406
                     /locus_tag="VUR46_001703"
     CDS             11678..12406
                     /locus_tag="VUR46_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5457087.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            12399..13136
                     /locus_tag="VUR46_001704"
     CDS             12399..13136
                     /locus_tag="VUR46_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5457088.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLTTVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            13149..13859
                     /locus_tag="VUR46_001705"
     CDS             13149..13859
                     /locus_tag="VUR46_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457089.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISALYSE
                     LDYNKYWYVLHTLIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSITNLGIKLLVCIWIMG
                     FEFSLLPKLIKLKEQNLV"
     gene            14402..14623
                     /locus_tag="VUR46_001706"
     CDS             14402..14623
                     /locus_tag="VUR46_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5457090.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            14929..15243
                     /locus_tag="VUR46_001707"
     CDS             14929..15243
                     /locus_tag="VUR46_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HET5457091.1"
                     /translation="METVNYKDLVAIGFPEHTSRNIIRQAKKIAVKKFEEARKNDKNE
                     VQLGCSPFDNKRLGIAPKNIVENLISISFSDIEGEKNGYIKDKEISRCIQRFKRKNLF
                     SN"
     gene            15170..16355
                     /locus_tag="VUR46_001708"
                     /pseudo
     CDS             15170..16355
                     /locus_tag="VUR46_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520162.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(16812..18158)
                     /gene="gdhA"
                     /locus_tag="VUR46_001709"
     CDS             complement(16812..18158)
                     /gene="gdhA"
                     /locus_tag="VUR46_001709"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET5457092.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKIYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            18604..19137
                     /locus_tag="VUR46_001710"
                     /pseudo
     CDS             18604..19137
                     /locus_tag="VUR46_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6902 a         2544 c         3393 g         6325 t
ORIGIN      
        1 tgtaaatcat ctagttgata atacacggca attagaagaa ctagctatct ttgaaagaat
       61 tcaaatttac caacgagata gaagttgtgt atatgattca ggagaagata caacttcagc
      121 agcaacagtt cttcatgact tactatttgg agaatggaac acggttgaaa aagagatgtt
      181 gaagataggg caggaacggt tgtgggtgat taacaaagag ttaaataata ggggggatta
      241 agttggcgag ttcaaacgtt gaccaaaata ggaatgcaac accaagttgg agtggatata
      301 tccatcaagg gaaagtagga tttttagtag cgttaagaca attgaaaaaa tgtattgatg
      361 ataaggcgcc tgattacgag aattatgtga ttagatatga aaatgctgaa gattttgata
      421 ttgttgataa caacgacaaa gttatatcta ggcatcaagt aaaggcatat atagatggta
      481 cgtcaaggga acaatattta agatacaaac aagaaaatat tgtgaggttg aggataagag
      541 aagtaatcaa aagatttgga aagaaataat tgatgaggaa ggatttcaaa tccatcaatt
      601 tgatgggcaa ggacacatac taactgtaga agttagtcct gattcaagat acttacacgt
      661 tattgtagca ataacagatt tcaatttatc tcggtatgag tatttaaaga aagacggtcg
      721 cagaaaaaaa tatactgata ataattcatg tattcaacta tatccataca ataaagagaa
      781 cgatctttat cattgtccac tttctcagga tgataataat gatacaatta gagattattg
      841 taaagctgaa ataaaagaaa ttttaaaatc aaagggtaat tcattgaatg atagtgtctc
      901 acatttagac caagtatatc tcaggtatgt aggttcttta ttggatcata gcattggaca
      961 agaacacagt gagtctggtt ttccagaaat atcctttgga gaaatacttt ccattattga
     1021 aacggaaact tctgaagatg aagtatatga aatgaaaaaa aatttgacct ataggtggga
     1081 aaaatatcat ggtgattatg caagtgacat tagagaggaa gattttaaac ttatggatga
     1141 aataaataat catttactgt cattgactaa agatgagttt tatgaatttg tgagaatgat
     1201 gttaccacac gaaaattcag atgaaaaatt tttagaattg tttcgtaatg ccccaatgga
     1261 ggatatattt tatgtattac tggagaaaat taagggattt tcgtttaaat cttacagtta
     1321 tttagatgat aatgagaaga gctatagaac ttcattgatt agtattcagg atagacctgg
     1381 gataattgca aaaaaaattc aagaaataat tgacaactca gaatttttaa aagctacttt
     1441 taatcatgat ttccttatta atagagatat agatgagttg catattggga atagaattga
     1501 tgaatttgat ggcatgctag ataatagata tcgtgaagaa tggaatacag gagtacaaca
     1561 taatatattt aaaccgaata tggaattcat tagcattgag aaagtaaaag aaaagaattt
     1621 gagtgtgccg gaggactaat atgagagaca tcgttataaa atttttacaa aataaccatt
     1681 ttaaccagtt ggatacagat tttgatttct atactaactc acaaaaatca gagtatttta
     1741 ttgttagtca atatagtcct gatgagctaa ataatttttt cgatgatgat aagacttcac
     1801 aagtaataaa agagtttgaa agggtatctc taacaccaga acatgaaaac atcaagaaaa
     1861 atacttctat gtttattttg gtagaagttg atgacttgaa ggaagtattt gaagacgaga
     1921 aagttcaacg atcaatttta ttgattgaag aggactatta ttattttaga aagttcataa
     1981 tattatacac tcgaaatggg ttattggatt tacgagataa agagactaat gaaatactct
     2041 atacttactt agaatctaat attgatgctt ttgaagatga tatgtttttt agtgagtcgt
     2101 attttatggc tatggaaatt ggagtaaaac taccattttt cacactccct aaaagaaatg
     2161 atatttatca aagtatagaa agtcagtatc aggatgataa ggatgaatta gataatagat
     2221 tattggattt ttatactaag aacactgatg agaaattatc aaaatcacta aaagatattt
     2281 ctaccgatga tgataatatt tctgatttac tacaaatagg agaattatta caatgaaaat
     2341 caaaaaaatt ttaataaaaa actttaaaaa tataaaggaa actagaatta ttgattttca
     2401 agagaatgta actttgtttg ttggaccaaa tggatttgga aaaactacaa tttttgacgc
     2461 aatagagtta tcattaactg ggaaaattcg tcgaattgaa gagtccgatt atagtgacgg
     2521 tagaagtagt tttagtgctc catattttca aaataatcct aatcaaaata cattcattga
     2581 gcttatgttg acaaatgatg agggtaattc tttgatagta tctagtcttt ataagagtag
     2641 tatgaatact gagggcagca atgtaccaaa gttttcattt tctaaatttc aaagaagagt
     2701 tcgggttggt ccaggaattt catttcaatc tgatgaagac tttgagggtt cgagtgaaag
     2761 agatatacaa aaggacatta gtcagtttct aggatatgaa tcagaagatt atagcttagg
     2821 tgatactttt gatttgtttc attatattca acaagatgaa acagcttatt atttgaagca
     2881 aaaagaaaaa gatagaaagg aacaattgaa ttttctgtta aatattggaa actatgttaa
     2941 taggaaaaat agattagagc gtttaagaag tactttatcc tctagtgaaa aggaactaag
     3001 agcaaaaaag ggtaaactaa aaaattcccc aattaagaac aatatcctat attcgaaatt
     3061 atctcttaga gcagatactg actttgcttt taacaataag tcgattattt ttgatgaaga
     3121 attgtcaaat gaaagtttaa atatatatct atcagaaatt actaaattac aagaatttcg
     3181 aaattcattt tctccaaaag attacttcct tagaaaacaa agtgagcaat ttgagcgaga
     3241 ggtgctggat gataaagatt ttactattta cttaatagtt agagaaatac ttgaaaatca
     3301 ggaaaatata gagtcaatta aacaaaatta tagtttaatt tcaaatgaaa aaaatttctc
     3361 atatttttta cttaaaaact atcttgaacg acaggacttg ttggaaaatg atagtaagtt
     3421 gtttaaattt ggaaaaagat tgaagagctt acttgatgtt gaaattgcta aaattgatat
     3481 caaatcaatt gagaattctt taaataattt tacaggatgg gaatttggca ggctatggat
     3541 tgaaaaattt gaacctaaat taacagaata taagtttaaa gaagggcagc tagatgatgg
     3601 aacagagtcg attaacaagc tactcgagat aagaactcgt ctaaaagaac atagcactgg
     3661 aaatcattcg gaatgtatat tttgtggtta tgattgggga gagagcgaga atttactggc
     3721 agcctatgaa gaaacaacga atcaactacg taaaaatttg actaattttg aaatagaagt
     3781 ttcaaatttg gttgaagaat taaatcaatt aaaaatggag ttacaaaatc agatccaaat
     3841 ggagcaagag aaactctttg ttattcctga tgattttttg gcggcgatac gatccataag
     3901 taattataat tttcctgagt cttttagcaa cttggttgta atgaactcag agattactcc
     3961 tttgcctgtt gataagagtg cttcgctaca agagtttgag aatttgaaaa cagagttaat
     4021 aagttcattg caagaaaaac tattgattcc aaatgaagtt tatggtactt tccttagagt
     4081 tgtaaataag agtgttgatt ttgaaaaact tttagaaaaa tattctattt tagctggaga
     4141 atcaataagg gaatatgaaa tttcttttga ccttttaccc atttccttgc ataaatttga
     4201 agagaacaaa gacaggttac tagtattttt aggggatctt agatctcaaa tagtatttga
     4261 ttattctaaa agtttagatt cacaaaatct atttgataaa tactttgcat ctaaggaaaa
     4321 aacttttgag gactgtacta tagaaagtat caatcaaaag agagaatata ttattaacca
     4381 gtttgaatta caaagtttaa cgatgtttca ccaaattgag aaacgtcttc aaatcattga
     4441 acaaacgatt acatatcttc aggatcgtgt tagggaatta aataataata taaagtctta
     4501 ccaagaacag atgattcaaa agttgaagct tcccttctat atgtacactg ctaaaatttt
     4561 acaaaattac caacaaggaa tgggagttct actaacaact caaaacaatt ctaatatcag
     4621 gtttatagca aatagtaata gtgagcagga tgtgatgtat caattgagtt ctggacaagt
     4681 agctgttatt tcgtttgctt tcactttggc actaaatact acatttaaga tttcaagagg
     4741 gttcaaattt ttatcaattg atgatccgat tcaagatatg gattctatga atgtatatgc
     4801 tttaattgat ttaataagac attcattatc agactatcaa attattatgt ctacacataa
     4861 tgatggtagt gctatgttta taaaatataa atttgaacta ttttcagatt ccgaaatatc
     4921 aaatgtaggg ctaaaaaata taaagaatat cttattattg gatgttgaag ttagcagttg
     4981 atgagactat atatattaat ggaaatataa aaaacatggt ttcattaaga cggtatttga
     5041 gagccttggc tttctttttt cttaccatca tttttcatgt tgtgatactt ttttcaaatt
     5101 taccttgcta tcctaatatc attactaaga aaatcaagcc ttaatttttc actgggggtt
     5161 tgggggcgga gccaccaagt tatcttatcg ttggctgtca aaactagaag gttttgacag
     5221 gctggcgata tgatttttgg gatattgtgg acacaatatc tgagctcgca aagaccgaac
     5281 aaggagagac tgaggtcttt aggaatcgta ctgacaatgt gaggcagcct tacattgtca
     5341 gacaagtata atgttgaaag gatggtaaga tgggacaaga aattaagtta atccgtaagc
     5401 aatttagaat cacgagacaa gaagaaaaac agataaaaga aatgatgagg gaacaaaaag
     5461 tggatagttt ctcagaattt cttcgtcaaa atttattgaa aaagaattat caggatagaa
     5521 tttttgaaag ttggttctcc ctttggcagt ctcaaaagtt tgaacagatt agtcgagatg
     5581 tgtatgaagt tctggttgtc gcaagagaaa atcatcaagt gactcaagag cacgtctcaa
     5641 tcttattgac ttgcgttcaa gaattgattg cagaagtgaa tcaagtacag ccactcagtc
     5701 gtgagtttcg tgaaaaatat atgggttagg aggatgtaat ggtttatcgc tatcgtacca
     5761 atctcaaaaa agtatttcta actgatccag aattacacca attgaatgaa cggatttcta
     5821 agagcaattg tcaaaatttt tcagtctatg ccagaaaagt tttgcttagt cccaatatgt
     5881 catttgtcac gattaacact gatacttatg accagttagt ttttgaattg agacgtattg
     5941 gaaataacat caatcaaatt gcgcgtgcga ttaatcaaag ccatctgatt tctcaggacc
     6001 aattacaaga attgagtaaa ggagtcggag aattaattaa ggaagtggac aaagaatttc
     6061 aagtggaggt gaaaagactg aatgagtttc atggtagtta ctaaacactt tgcgacgcac
     6121 ggaaaaaaaa tatcgtaggc gtttgattaa atatatcctc aatccagata aaacagataa
     6181 tctaaaatta gtatctgatt ttggcatgag taattactta gattttccta gccatgcaga
     6241 aatggtagaa atgtacaatg ttaactttac taataacgac aagttgtacg agtccagaaa
     6301 tgaccgacaa gaaaaacact aacaaactat tcatgcccat catctcatcc aatcattttc
     6361 tcctgaagat aatctgacac ctgaagaaat taaccgcatt ggttatgaga ccatgatgga
     6421 attgacagga ggtcgtttta agtttatcgt agcaactcac acagacaaag atcatgttca
     6481 taatcacatc ctaatcaacg ctattgaccg caattcagat aaaaagttga tatggaacta
     6541 tgccttggaa cgaaacctcc gtatgatttc agaccgtatt tctaaaatgg ctggtgcaaa
     6601 aattattgag aaacgttatt cctatctaga ttataaaaaa tataaggaat ctagtcataa
     6661 atttgaattg aaacaacgtc tttatttttt gcttcagcaa tctaaatcgt ttgatgattt
     6721 tttagagaaa gcaaagcagt tgcatgttca gattgatttt agtcaaaagc atagccgttt
     6781 tttgatgaca gatagaacga tggtaaaacc aattcgaggt cgccaactta gtaaacgaga
     6841 tttatatgat gaagactttt ttaaaacata ttttgccaaa caagagattg aaagtcgttt
     6901 aaaattttta ctaaagtctg tttattcatt agaagaattg catgtaaaag ctaaagagtt
     6961 gaatctaacc atcgagttaa aacagaaaaa tgtgatgttt accctagaag aagatggtaa
     7021 aaagataagc ctgagtcata aaaaaattag cgataagaaa ttgtacgatg ttcaattttt
     7081 taatcgttat tttgaagata gagaagttag agatattcaa gtattagaaa atcttcagga
     7141 agattttcag acttttcgag aggagcagca taaggagaaa gtctccgctg aagaaatcga
     7201 ggaagccttc aagaaataca aggaaaaacg agatgctatc catgagtttg agattgaact
     7261 tacggataat cagatagaga agttggttga tgatggtgtc tatatccagg tttcgtttgg
     7321 tatcaaacag agtggactca tctttattct taactaccag ctagatattt ttgaggaaga
     7381 caatcataaa aaatataaag tctacattcg agaaacgtct tcttactttg tctataataa
     7441 agaaaacatg gataataatt gtttcatcaa gggtaggacc ttaatcagac aattgagcaa
     7501 cgatagccaa aaactcccct atagacgacc aactttaaaa agtcttcaag agaagatttc
     7561 tgaaattaat cttatgattg aactatctaa cacgaacaaa caataccaag aaatcaaaga
     7621 tgagcttgta ttagaaattg cagagattga tatgcagcta gaagaaaccc aagaaaaaat
     7681 cgccacctta aacaagatgg cggaagtact tatcaatttg aagagtgaag atcatgagac
     7741 tagaaaatta gctaagtatg attttgacca aatgaacatg acggaatcaa taatgttaga
     7801 tcgactcaat acagatattt taaaattaca acaggaactt ggtaatgaaa ttaataaata
     7861 tgaggagata gctagaagat tggatttgtt tgtgaaaatt attaatacca ataaatttac
     7921 agttctaaaa tttcacgaga atgccttact agaataatat tatttacgac taattagtta
     7981 aaagatagag aataatttca tttatttttt gtttactagt ttattaaaat ggtcagtata
     8041 gtgtaatttt aacttatctt ctcctaaaat atcgaagact tgtatggctt gtttcatttt
     8101 ttcaattcca ctggttgatt ggcaacgttt aaattcaaag taaccagttg catagagaaa
     8161 aactggttgt tcataaaagt ttagtttatt atccaacaat gtctttatct tactaattaa
     8221 ataggagcaa ttagaaaatt cttccttacc aatgcttaga ataaagcaat taatagcaag
     8281 ctgagagaca atctgcttat tagttttatt cagagatgag taaatatagt tatttaacat
     8341 ctctttagtt aataagaagt aggagttgta gttaattgtg cgtacacagt taactaataa
     8401 aatgatttca taatagcccc atttttcaac tttgaaaaga tagtctgtca gatgaagaag
     8461 ctcttcatct gatggaatga tgttcgaatc cattgtgtgt aaaatagatt ttaccattgt
     8521 tttctcaaaa gaatttagag tgtaatcaga agtatcagaa agtagacatg ctatattatt
     8581 gatactttgt gatgaatatt gcttacgaat gtactgtact agattagcaa atgattcgga
     8641 actggtatag tcgtcattgt gtaaaacaag gaacccatcc aaagtaatat gtaatttgtc
     8701 taaaatattg attagtcgaa tacaagatat ctctgactcc ccacgttcaa aacgagatat
     8761 ttgtgatttt gaaagatgtt catctgctac agagcataga ctaatttgtt ttcctttacg
     8821 aacttttcta agtgtgatgc caagttttga tttcataatt tcccattttc ccaacaaaaa
     8881 ttaaatccgt ttttatttat tgtacaataa ataaaaacgg aaaggaagtc caagtatgaa
     8941 gaaaatttca aaatttttac cgattttggt tttggtgatg gatattatca tcatttaaaa
     9001 aagtgtatta attattgtat ttcacaatta gataatataa cagtaacagg tttagcacac
     9061 ggttattctg gagtagcaat gtcattatca tattattatg aaattaatcc tagtacagat
     9121 atattaaaat gtatagagga attactatat aaagaagata aatgtttcaa taatatatta
     9181 aaaaattgga aagacataag aagaaatcat aatgattcct ttcctaattt ttggtgttat
     9241 ggagctccgg gcattttgtt agctagaaaa gaaattttcg ataaaactaa tattgggaat
     9301 aatgatttat caataattga aaatgtatta actaatgtag aaaaaataag agaattgaat
     9361 ttatgtcatg gttctgtagg tactatcagt tgtcttgatg caatattgaa agatgaagaa
     9421 aacctattaa taaaagaatc tatagatttg tattttgata atgtcgtttc tcaggttatc
     9481 aaaccagaat taagtacgga tttgaatact atgaatacat tttcttttat gctaggagta
     9541 tctggagttg tctatgaaat atctcgaaaa caagatgata gattactgaa tgttttatta
     9601 ctagagttaa agaggacatg atgactagaa aagtacctaa tattgagcaa atgtctcaaa
     9661 tagaatgtgg tttctgttgc tacttgtcca tactacattt ctataaaagc aaagagacat
     9721 tactagattt aagacgtgat atagaaaaag ggagagatgg ttatagtata ggtgacttga
     9781 aacagttatt gaataaacga aattttgata ctggttcata tcaagttaaa gatgtaaata
     9841 aaattagtga acttccgtta ccattaatag cattttggga taatcaacat tatgtagtta
     9901 tttacaaagt aaaaaagaat aaggtctata taatggatcc ttctaaagga tatgtaaatt
     9961 atgagtttaa ggagttttca aaacatttta gtaatatagt actgctatca tttcctaacg
    10021 aaaattacca atctttgaag tcacagtttc cttcaccatg gataagagta ttctctagtt
    10081 tttcaaaggt aaaaggtcga ttgattttga cgttgctatt ttcaataata agttacttaa
    10141 taatactttc tataccagta atgacttcaa agtttattaa ttctgcatta ggtaatacat
    10201 tttcttttca aacctcgttt ttaattttat tttctctact ttgtttgtac cttatttcta
    10261 tcttggctag gagtatggga attctatttt ctaatatatt ttttagtaga gatattgaaa
    10321 gttttacatt taagcatttg cttaaactac catatagttt ttttgaactc agggcaaaag
    10381 gagatatttt atacagaatt tctagtctta gtggttttag ggagctattt actaaccaag
    10441 ttgttggggg agtagtagat attgggacta ttctaagtgt tgtaatatat atgtttctta
    10501 gttcaaaaac attatcaatt atagctctta tattgagttt aatcaatttt ttgtttctgt
    10561 ttagtactag aaaaataatg tatgatacgg ttaatagaga attacaagaa caatcattga
    10621 tttactcagt agaaacagaa gcattaaata ctatttcttc aataaaaata tcgggattag
    10681 aagatgaaat atatgaaaac tggtctaagt atttaaaaaa tgtattgaca aagtataaaa
    10741 aacgaagtgt agaatagata ttaaggacct atctttctct tattccaaag actcagctcc
    10801 tgtaatagaa aatttaaatt tgactattga gtcaggacag agaattgcac tagtcggtca
    10861 atcggggtca ggaaaaagta cgttattaaa aatactatta ggattatata agattgatac
    10921 aggaaaagtt ttatttgatg gtataaatat taatcaaata gataaaaaaa tattaagtca
    10981 aaatttagga gtagttccac aagattcgtt tttattgaac agaagtattc ttgataacat
    11041 aactttaaag cacgaagtta cttcacaaaa gatagaggaa gtttgtaaag cagttcaaat
    11101 ctatgatgaa atcatggcta tgccgatgaa atttaatact atcatctcag agatgggttc
    11161 aaatatttca ggtggtcaaa gacaacggat agcactggca cgtgcattaa taaataatcc
    11221 tagtattgta attttagatg aagcaactag tgcattagac actattaatg aggaaagaat
    11281 aacaaagtat ataaaaagtc agggctgtac taaaataatt gtatctcata gattgtcaac
    11341 gattaaggat gcggatatta tttttgtaat gaaaggtggt aagattgttg agtcaggaaa
    11401 tcataagtac ttaatggctc ttggtggaga gtactacagc ttatatacaa aaaggaaatg
    11461 aggtgtaaag aaaatgaaga aagtaaatga atatgtaatt tcaacagcag cctcactagg
    11521 ggtgatgatt ggaatagtat ttgcaatttt tttagatttt ccagttgaat atggtatttc
    11581 tttaggattg ttgaatggaa tagtattggg ttcgctgatt ttttacaaaa acaataagaa
    11641 ttaagcacaa ttttttgctg taaactaagg agtagagatg gctatagttg aaattataaa
    11701 tctaacaaaa agctttaaag atattgaagt tattcataac acttcatttt atttaaataa
    11761 gggaaaagta tatggttttg ttggaccaaa tggggctgga aaaactacaa ttatcaaaat
    11821 gattctaggg attttaaaac cagattctgg gaaaataact atttttaatc aaaccgtaga
    11881 acagaattcc gaaaatatat tatctaggat aggattagtt ttgggacctt cattttatgg
    11941 tcatcttgat gcttataaaa atttgaagtt aatagcaaat atgaaagggc ttagtttaga
    12001 tactgaaaga cttaatgaat atctatcaat ggtaggatta aaagatgtta aaaagaaaaa
    12061 agtgaaaaat ttttcaatgg gcatgaaaca acgtctaagt atagctgcat cattgttagg
    12121 tagtccagaa atattaattt gggatgaacc aatcaatgga cttgatccac agggtgtaat
    12181 tgaaattaga agtttaatcc gttttctaca ggagaaaaaa ggtattacat ttttaatatc
    12241 aagtcatatt cttagtgaac tggataaagt gatatctgat attataatta taaattatgg
    12301 gaaagttgaa ttttttggtt cttgccacta ccttttacaa aagtataatt gtcgaaatct
    12361 ggaagaagcc tacttagctt gtttagctgg aggtgaatat gattaaatta gagtttctaa
    12421 agcagaaaaa aagcatctta tggtttgttc ttatttttcc aataattctg aatgctttgt
    12481 tatatataga cttaactttt aggtatcgag gttatttatt ggtgcatcaa aatgaacttg
    12541 ctttatctaa ttggcagtta atttttaaag aacaaacaat attttatttt tctgaactat
    12601 tttatttagt tctatcttta ataatttacg aagtgtttgc agtagaattt aaaaatgatg
    12661 catggttaac cgtaatttca ttgccattta gaaacaagta cacaataaat tctaaattac
    12721 tcactacagt ggtttacaca tttacttttt ggttgtctga ttatattagc ttatacgtta
    12781 ttgggaaggc tattgataac agtttagaga ttggtttgat tttcttttta aaaacattta
    12841 ccattcaatt aatttcctcg ttgatgataa tgttattata ttttctaact ttagtactta
    12901 taaggaaaat ttctggaata ataccaattg gtattataat gatgatttta acaattagca
    12961 tatactacaa cgattataat tttaagattt acttaccatt tacttatctt tctcatgctt
    13021 ttagagtgac tgaaagtcaa ttttatatga ttttactatc taatataata atcatcgtac
    13081 ttttttatat attaattcgt aaattgaacg aaagaagttt tgagatgaaa ctttaatagg
    13141 taataaaaat gaagttactt aaaaatgaat tgattaagag taaaatattt ttatttatta
    13201 ttgttgacat ctgtattcag attctagtca ttctagctat aaaaacatat attttagata
    13261 tttcggcact atactcagag cttgattata ataagtattg gtatgtttta cacactttaa
    13321 tatatatgcc aatgattttt cctatacaaa ttttgtatca aaatctaaga gaggcattga
    13381 ttgaagataa taataatggt tggaatatca tggtgattaa cactaataat ctcgtgaaaa
    13441 tcatctatat aaaagtaacg ataaatatcg tgagatgttt tatttgttat tttgtttata
    13501 caattttttc tttaattcaa ttaggtggta tgggaactga tatgttatta accaatataa
    13561 tatttcccaa tataatgtca tttcttttat ttttacctat agctatcttt atgcaaattt
    13621 gctgtataag atttgattcc attttagcaa aggccttacc taatattttg ctgatactta
    13681 ttgttttaat cacgtttcag agtgattgga atatatttat acctgcaact tattattata
    13741 cagaaattca gtcaattaca aacttaggta ttaaattatt agtttgtatc tggattatgg
    13801 gatttgaatt ttcccttctt ccaaaactaa taaaattgaa agaacaaaat ctagtttaaa
    13861 tgttgctcga aaattaaata attgaatacg attaacaatg aaacaataca acgtgagtca
    13921 tgacttcaaa gtaattgatt ttatgattct ggtttcttac gcttaattaa gcaagttgta
    13981 ttcactttat caaattgtta ttactctaaa aagcgtctaa cagctataga gtgtctgttt
    14041 gcttctcttt acttttattt taaataattc attaaccttc cgtaagtgcc caataataag
    14101 gtgtgttgaa gaagtctgag ataaaatagt tctcagtcac aaaaaaaact atagattccc
    14161 attggtgaac agctccctgt caagtagaca gtaaaataat ataaaatctt aagcgacctg
    14221 attcctgaat tccagtggag tcaggttgtt ttttaaccgt ctttcttaat attgtcttac
    14281 ctataataga tatgcttatg aaaagtgttt aataaattaa ttttagttca aaatgtccaa
    14341 tttggacact ttgaatgatt tcttagtttt atatattata cttttctcag gagaaagcta
    14401 gatgtacaga cgtttgagag atttgaggga agatcacgat ttgactcaaa aacaaatagc
    14461 taaaatactt tcgtttacaa actcagctta tgctaaaatt gaacggggtg agcatacgtt
    14521 aacagcagat gtattggtaa ctctctcaaa cttttacgat gtcagtacag actacctatt
    14581 gggattgaca gattttcctg ataaaattcg ctttagaaaa taatctcctc aatttcatag
    14641 agtgtgaaaa tgaggggatt ttttatttgt tctttgaaaa ttaaatagtt caaaatggta
    14701 ctttcctcat ttgtggagca aatttgaatg gctcgccatg ataagagcga ttttaaaacc
    14761 atcaataaaa tagagcgata ctttatatgc catgatacaa atgatataca atgatacttc
    14821 tgaccgttca ggctgccaac gtaaaagagc agcaagtgaa attcttatga tgacttcatc
    14881 agtcatgcca tggaggtgaa aaaatctaag aaaggaagta gtaaaatcat ggaaacagta
    14941 aactataaag atttagttgc gattggtttt ccagagcaca catctagaaa tattattaga
    15001 caagcaaaaa agattgctgt aaaaaagttt gaagaagcta gaaaaaatga taagaatgag
    15061 gtacaattag gatgttcacc tttcgataat aaaaggttag gcattgctcc taaaaatatt
    15121 gtagaaaatt taattagtat ttctttttca gatatagaag gtgagaaaaa tggttatatc
    15181 aaagacaaag aaatatcaag gtgtatacaa agattcaaaa ggaaaaattt attttcaaat
    15241 tgaattagga gttgatccaa taactgggaa aagaattcaa aagaaaggaa ggaaaaatca
    15301 acagggacta ccgtttaatt cttttaagga agcatatgaa gagatacttc gtctaaaaca
    15361 tgaatttgtg aactctacta ttaataatag ttttctaact tttagagagt ttatggaaga
    15421 gatttattta aaatattatc aacaaaaagt tcaatctgta acttatcaga ccgctttacc
    15481 acatcatcag ttatttatta agcaatttgg tagtaaaaaa ttatcagata ttagtactat
    15541 tgactgtgaa agatttcgct tagctattat agacaagtat tctagtaatt atgctaaaaa
    15601 tatgtggtag atttaaagca tgtctgggct atgcagaaag attgggttat attgataaag
    15661 ttccttttaa aggattagat aatcctagag gaaagtaccc tgatacaaaa ttttggacat
    15721 ttgatgaatt taagaaggta ataaactctt ttgatattag tgagtatgag ggactccata
    15781 attgcatgac gatctggtta tattttatga ctggtttaag agttagtgag ggtattgctc
    15841 ttaaatggga agatattgat tttgaacgta aatggattca tgttcattcg acaattgaga
    15901 aagataaaaa cggtgtatgg tatgttaaac aacaaacaaa gacagtagca ggggatcgta
    15961 aaattgattt agatgatttt acgattacaa tacttaaaaa atggcgagaa gttcaaatca
    16021 agaatgatga taaagattat gtaatatcac gttttggtgc ccccttgtgt aagtctacaa
    16081 tttctaggat aataaaaagg catgctaaga ttactggtgt accagaaatt acggggaaag
    16141 gattaagaca tagtcatgca tcttatctta taaatgtgtt acataaggat actttatatg
    16201 tttcatatcg attaggacac gctgataagt caaccacgtt gaatacatat agtcactggt
    16261 attattcagg tgattcaaca atttcagaag agattacaaa cagtttagat aatcttggat
    16321 tatcaattta cctaccaaat tcctgccaga gttgaaaatt gaggaattaa cccactaata
    16381 ctgggagaaa ataggatttg caaattgtta ctcttaaata atagagcaac tacagtagta
    16441 gcttaaaaac atgattaaat cgctattttt aggagtagcg gtttttcttt ttgtttaata
    16501 ctctttgaaa atcaaattca aaccacgtca gctttgcctt gccgtactca agtacagcct
    16561 gcggctcgct tcctagtttg ctctttgatt ttcattgagt ataaaaaggg tcaagtaagt
    16621 atagtaaatt gaaataagat atgaacaaat cgattaggaa agtcaaatta atttctagaa
    16681 atatgttaga aattggtttg aattccgcaa tcaatttgtt cagtttttat ttcatttaat
    16741 tagaatttcc caactgtcta actcaactaa aaatccccaa tcgtagtgat tgaggattaa
    16801 gcaaataaat cttaaacaat accttgggca atcatagcgt ttgctacatt ttcaaatgca
    16861 gcaatatttg ctcctgcaag atagtcttta tcaagaccat atgtttctga agttgtttta
    16921 gctgtgttga agatgtttgt catgatgtct ttgagacgtc catcaacttc ttcacgagtc
    16981 catgagagac gaaggctatt ttggctcatt tcaagggctg aaacggctac accaccagcg
    17041 ttggcagctt tggcaggtcc gtagaagata ccattttctt tgtagatttt gatggcatca
    17101 aggtcgctcg gcatgttggc accttcagat acacagataa cgccttgagc aaccaaacgt
    17161 ttagctgctt caccgttgat ttcgttttga gtagcacatg gaagcgcaat atcatagttt
    17221 ccagcgtaag tccatacaga accttcgtga tatgttgcag ttgctttctc agctgcatac
    17281 tcagtcaaac gagcacgacg tttctcttta acatcaacca aaagatcgaa gtcgatacca
    17341 ttttcatcga tgacataacc gtttgagtca gatacagaga tgacagtagc gccaagttca
    17401 gtcgcttttt gaagagcgta ttgagcaacg ttcccagaac ctgaaataac gactttctta
    17461 ccagcaaagc tgttgccatt tgccttgagc atttcttcag tatagtaaac caaaccgtaa
    17521 ccagttgctt ctggacgaat caagctacca ccaaatccaa gaggtttacc agtcaagaca
    17581 ccagcatcaa attggttaag gcgtttgtat tgaccgtaaa ggtaaccaat ctcacgtcca
    17641 ccaacaccga tatcaccagc aggtacgtca agtgatggtc cgatgtgttt ttgcaattca
    17701 gtcatgaagc tttgacagaa acgcatcact tcagcatctg ttttaccttt aggatcgaag
    17761 tctgatccac ctttacctcc accgattgga agtccagtca agacgttttt aaagatttgt
    17821 tcaaatccga ggaatttcaa gatcccttgg tttacagttg ggtggaaacg aagtcctcct
    17881 ttgtatggtc caacagctga gttgaattga acacggtaac cacggtttac ttgaattttt
    17941 ccatcacggt caacccaagg aacacggaaa gaaattacgc gctcaggctc agtaatacgt
    18001 gccaagatat tttcttcgat atactcaggg tgtttttcaa atacaggttc caaagtgttg
    18061 aaaaattctt caacagcttg gaggaattca gcctcgtgcc cgttacgagc ttttacagtt
    18121 tcaaacacgc tttggatata ttctttagca gatgtcatat cgttctcctt ttgttgtcat
    18181 attttattac atgagctatt atagcagaat ttttttaaac tgtaaagaga aaaacaaaaa
    18241 ttttctaaaa attctttcaa tttgtttttt ggtttcggct tttcttgaac tgataaaaat
    18301 caaacctttt tcttggaaat atctttctca aagagaaaat cttaaagtat gctataagaa
    18361 aagaaaatgt ttagcaattc agaaatcact tgttaattta tccgtgatat gttagatttg
    18421 ccagtaaaac tatgatcatt ttggaggaaa gcaatattta catctcctta ttcatggcag
    18481 gattttttat acaagtatag atgtcttgct ggagttgaat catggaaccc aagcggttat
    18541 tgagatttag aactatcatc agaatttttt cattagactt gttcggtaac catacagtac
    18601 tatactatcc atgaacaaga cctagaaaaa gtagccttat ttcttaaaag ttttaatagt
    18661 ttaaagcact tagcacctgt ttatattgat gagacaggat tcgatactta tttttatcga
    18721 aagtatggtt gttctttaaa aggtcagtta ataagaggta aagtatctgg aagaatatat
    18781 cagaggattt ctttggttgc agggctaaca aatggtgagt taatcgctcc aatgacttac
    18841 gcagagacga tgacgagcga cttttttgaa gcttggtttc agaagtttct cttaccaaca
    18901 ttaaatacac catcggttat tattatggat aatgcaagat tccgtagaat gggtaagcta
    18961 gaagtcttgt gtgaagagtt tgggaataaa cttttacctc tccttcccta ctcacctgag
    19021 tacaatccta ttgagaaaac atgggctcat atcaaaaagc acctcaaaag ggtattacca
    19081 agttgcaata ccttttacga ggctcttttg tcccactctt gtaaatgtct aagataagag
    19141 ctatactagg taaataaaaa tctc
//
LOCUS       DAVDHZ010000040        18833 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000040 DAVDHZ010000000
VERSION     DAVDHZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.041"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(1..866)
                     /locus_tag="VUR46_001711"
                     /pseudo
     CDS             complement(1..866)
                     /locus_tag="VUR46_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1338..3913
                     /locus_tag="VUR46_001712"
                     /pseudo
     CDS             1338..3913
                     /locus_tag="VUR46_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            4214..5053
                     /locus_tag="VUR46_001713"
     CDS             4214..5053
                     /locus_tag="VUR46_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET5457093.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            5071..6909
                     /locus_tag="VUR46_001714"
     CDS             5071..6909
                     /locus_tag="VUR46_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5457094.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLILPNNQTIEHSKELLVIL"
     gene            6922..8337
                     /locus_tag="VUR46_001715"
     CDS             6922..8337
                     /locus_tag="VUR46_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET5457095.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            8929..9975
                     /gene="pheS"
                     /locus_tag="VUR46_001716"
     CDS             8929..9975
                     /gene="pheS"
                     /locus_tag="VUR46_001716"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET5457096.1"
                     /translation="MSTIEEQLKAFREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFNQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            9975..10484
                     /locus_tag="VUR46_001717"
     CDS             9975..10484
                     /locus_tag="VUR46_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457097.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTVSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            10561..12966
                     /locus_tag="VUR46_001718"
     CDS             10561..12966
                     /locus_tag="VUR46_001718"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET5457098.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGHLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEAALFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(13034..14035)
                     /locus_tag="VUR46_001719"
     CDS             complement(13034..14035)
                     /locus_tag="VUR46_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET5457099.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            14191..14637
                     /locus_tag="VUR46_001720"
                     /pseudo
     CDS             14191..14637
                     /locus_tag="VUR46_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            14763..15029
                     /locus_tag="VUR46_001721"
     CDS             14763..15029
                     /locus_tag="VUR46_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5457100.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            15290..17539
                     /gene="metE"
                     /locus_tag="VUR46_001722"
     CDS             15290..17539
                     /gene="metE"
                     /locus_tag="VUR46_001722"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET5457101.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            17603..18469
                     /gene="metF"
                     /locus_tag="VUR46_001723"
     CDS             17603..18469
                     /gene="metF"
                     /locus_tag="VUR46_001723"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET5457102.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPRFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
BASE COUNT         5850 a         3233 c         3976 g         5774 t
ORIGIN      
        1 ttccattgtt ttagagcctt caaattgacg ttgaatgaga ttctctgcct ttttgccaac
       61 atctccttta tgagaagaat attttcgttt ctgtcgcatt ttagcttgta aattgagtac
      121 tttcatcaag ccttgaactc ttttatgatt taccagataa ccacgatttc ttagttctaa
      181 ataaattcga cgataaccat aatttccctt gtgttcgata aagatggatt gaatttcagc
      241 tttaagctct tggtccttat ctggtttatc tagctgtttc aagtgatagt agtaggtcga
      301 acgagctagt ttaatggctt ttagaagaag agctaacgaa aactcagtca ttaattcttg
      361 aacaatttct gtctttcttc tttctctttt tcctccttca atcggagttc tcttaacttt
      421 tttaggatgg cattctccgc tctcaggtac tcattttctg attgaagacg ttctaattct
      481 gtcctctctt caggtctcgt ttttggatta cgtcccattt taggtactct ccctcttggt
      541 ttctcaacaa tagtataccc gtttttcctg tattgtgcta gccagttaag aagtatcgta
      601 cgacttggga gaccgtattc aagagaaact ctatctttag tccagccttc atgtcagact
      661 ttatgaatca tttcttgttt taaatcagga gaatagtaac gattttttcc ttttttgccg
      721 aactctattc cgtaacgatc aatcaattta atcatgtacc taagattaga attgtttatc
      781 ccaaatttat ttgaaagctt ctctaagcta tatccttgtt ttctaagttc atagatctga
      841 actttatcat cataagttaa tttcataata aaaacacccc aaaagttaga ttttttctgt
      901 ctaacttttg gggtgtagtt catgtacacc tgatatgatg cgttttttga attttataga
      961 ctgctcgttt aaactctatt tacctcgtac attccggagc gagatggact attggtcgca
     1021 tacaaaatga gtgttattcg gattttattt tcgtgtacaa tttcagctat tcttgttata
     1081 atcagcctat aggaatcaag gaggtgactc ttatggctgt ttttgcgtct ttggatggaa
     1141 ttgtggtaga aatacttgat gtcttttttt cttttaatgg ggatagtgag tttttcttgt
     1201 gtatagcatt ttgaagctgg aataggacgc catgactgct aaaagatttc tataaattaa
     1261 tttgattttc ctaatcaatt tgttcatatc ttatttcatt ccactgtaaa cgtcttaaag
     1321 acaagagtca gtttgtgatg gaacgctctc ggttcgagga gatgttccaa cttcaaagta
     1381 gtcacttgac gacgcaagaa aaattacaat tgtttacctc cgtgtttgct ggacgttatg
     1441 atgtttatgc taagaatttt atcaatgaac aagggaaaat tcagtatttt ccttcctatg
     1501 attatggttg gaagcagttg ccacctgaaa aacggagttt ccagacattg acgaactccg
     1561 ttttgaaatc tcattttcgt ggggaggcag ctatcggtat ctttcctatg cacttagatg
     1621 atagctgtta ttttttggta ctggatttgg atgaaggaga ttggaaagaa gctggtttaa
     1681 ccattcgaag aatagcaagg gaacgccaga tggaagccca tttagagatt tctcgttcgg
     1741 gttacggact ccatatttgg ttcttctttg aggaagcgat tctgagtcga aaggctcgcc
     1801 tgtttggaaa gaaactatta gaattggcta tgcaggaaag tatgcaactg tcctttgatt
     1861 cttttgatgg catgtttcca aatcaggatg ttcttcctaa aggtggattt gataatttaa
     1921 tttcccttcc ttttcaagga gaagcttatc atcaagggcg aacggtcttt gtggatgaac
     1981 attttcagcc ttatgaagat caatggaggt atctacaaga aattcagagg atttcaactg
     2041 ctaaagtggc actgttaatc caagaggagt taggcaagca agaattggat aaggagttga
     2101 aggtcgtttt atccaatatg atccaacttg aaaaatcgtc tgtgacatcc aaggcacttt
     2161 ttttcttgaa aaatatggct tccttttcta atcccgaatt ttatagtaga ttgaaactag
     2221 aatagtatac ctctgcttct aaaacattgt tagaaatcga tttgactttc ctgatcgatt
     2281 tgtcctgtta ttatttcatt ttattatatt taaagcaggc tatgcgacag ccaacctatc
     2341 aaattcctga gcgaatgtat ttatttggag aatccgatta ttatttatgg ctgccaagag
     2401 gcttgttata tccattgcaa gataaattta agcaggtagt tgtggaggat aggagaaaag
     2461 tacaaaggtc tattagagta gcatttaagg gagagcttac tttggagcaa gaattagccc
     2521 tgtcagatat gaattctaaa gaaaatggtt tacttcatgc gggacaggtt ttggaaagat
     2581 cgttttaggt gctgctctta tctctgaacg taagacaaaa accattatcc tagttcataa
     2641 tagacaactc ttagaccaat gactggatcg tttaaagtgt tttttgactt tcgaagaggc
     2701 agaagctacc cgttatacac catcaggtcg tgaaagggta ataggctatg tcgggcagta
     2761 cggtggggct aagaaatgac tgagtaaact ggttgatgtt gttatgattc aatctctatt
     2821 taagttggaa aatagtcaaa gtcttttgga tgagtatgag atgatgattg tggatgagtg
     2881 tcatcatatc tctgccttga tgtttgaaaa agttgttgct cagtttagag ggaagtatct
     2941 ttacggtttg acggctacgc ctgagcgtaa gaatggtcat gaacctattg tttttcagag
     3001 aaattgaaaa gaccaaagca agtaatttta tacagctcag tgattggatt gctacagact
     3061 cagcgaggaa tcagttgatt ctcaaggata ttctagccca agtggcagaa ggacggaata
     3121 tcttggtttt agttaatcga attcaacaga tagatgtctt tgaaaagtta ttgaaagaga
     3181 aagagggtga tgactgttac attattagcg gaaaaaccaa agtccgagaa agagaacgag
     3241 tttactggag acgttagaac agttagataa agggtttgtt ttgttgtcta ctggaaaata
     3301 cattggcgaa ggttttgact tacctcagtt ggacacgctt atcttggcag cacccttttc
     3361 ttggaaaaat aatttgattc agtactcagg tcggattcat agaaactaca aggataagtc
     3421 tttggtgcgg attttcgatt atgtggatat tcatgttcct tatttagaaa agatgtttca
     3481 gaaacgacaa gtagcttatc gaaagatgga ttatcgtgcc attgagggtg aggagaaaca
     3541 attcgtttat gttgatagta gatatgagaa ggtgttgaga gaggacttag caggggaaag
     3601 acaggaatgt ctgcttattt taccttatgt gcaccagaca aaactgatga attttctaaa
     3661 agaatttagg attagtcaaa ttgagatatg tataccagag acggttgcaa ataaagcatg
     3721 gctagaccag ttgaagagcc agaaaattaa agtgtctttt actcaatcaa aaatagtaac
     3781 gcctattctt ttggtgaata agactattgt ttggtatggt gcaatgccat tattagggaa
     3841 ggtagatgag atgaccatat tacgtttgga atcagctagt atagtttctg aactagtggc
     3901 aggtttacga tagagaaaat ttttaaaaat ttctatgtat gattttcatt tctttagtga
     3961 gactgttgcc attatcacat tcgaatcaca caaaataaaa aaatttttat aagtacttga
     4021 caaatagatt gaaatatcat aaaataaaaa cggttacaga gttattgatt atttaagctt
     4081 catgtcacca ttaaaaattg aaataaaagg atgttatcac taatacaagt gagcaggaac
     4141 ctatttaatc acatcagaag aagtttcttg atgtttttta agtaggttcc ttttatttta
     4201 aaagggaaat tttatgatca taaaacgaat actaaaccac aatgccgtaa ttgcgcaaag
     4261 taaaaaagat atcgatattc ttctttttgg aaggggaata gcttttggaa gaaaaattgg
     4321 agataaagta aatccaattg atattgagaa aagttttttt ctcaaaaata gagataatat
     4381 gacccgtttt acagagatgt ttattaacgt tcctttggag ttggtgtaca tcaccgaaaa
     4441 aataattaac ctaggtaaaa taacattggg taataatttt gatgaaatta tctatattaa
     4501 tttaacggat catatttctt cgagcataga acgttataag gaaggagtta ttatttcgaa
     4561 tcccctacgc tgggaaatct cgaaatatta taaagaagaa tttgaacttg ggaaaagggc
     4621 tttacaaata ataaaaaaag agttaggtat tgaacttcca attgacgaag ctgcattcat
     4681 agcgctacat tttgttaatg ctaatttaga aaataatttt caagagtcgt ataaaatcac
     4741 tgaaataatt atgggaattg agaaaatcat tcaagatttc tattgtactg agtttaacca
     4801 agattctatt gattattata gattcataac tcatataaaa ttatttgccc atcgcttggt
     4861 tgaaaataca acttattgtg acgatgatga tgaagacttg ttagcattaa tgaaaaataa
     4921 atatcctaga gaatatgaat gtggtgaaca ggtggcaatg tttatacaaa ctgagtacaa
     4981 ttatttgttg acttctagtg aattagttta tttgatggct catattcgtc gcttaacaaa
     5041 aaatttagat taatagaata ggagaatacc atgagttata aagatacggt acaaaaaatc
     5101 ctcgatgtaa ttggaggtga aaaaaatgtc aatagagtta cccattgtgt aacacgttta
     5161 agattagaat taaaagatga aaatttagtc aatgatgatg atgtgaagaa gataccaggt
     5221 gtaataggta ttatgaaaaa gaatggacaa tatcaaatta tacttggtaa tgatgtagct
     5281 aattattata aagaattcgt taaacttggc aattttgaat ccgattcagt tgttcaaggg
     5341 cacaaaggga atattttaga aagaatcatt gaatatatcg ctggttccat gactccaatc
     5401 attccagcaa tgttaggggg aggtatgctg aaagtcttgg taattatttt accaatgctt
     5461 ggtatattgc aatcagattc tcagactatt gcttttttga cattttttgg ggatgctcca
     5521 tattatttct taccgctgtt attagcttat tctgcatcac aaaaattaaa agtaacatct
     5581 acattagcta tgtctgtagc aggtgtactt ctccatccaa attttgttca aatggtgcaa
     5641 tcagggaatc ctcttagttt atttggtgca cctgtgacac cagctagtta tggttcgtca
     5701 gtcgttccaa ttcttattat ggtttggttg atgaaatata ttgaaaaaat gattgctaaa
     5761 ttaacaccag ctgttactaa gagttttttg caacctacgc tagtattatt agtatcaagc
     5821 tgtattgcct tagttgtagt cggacctatt ggagtaattg ttggtgaagg attatcaaat
     5881 ctagttgggc aaatgtatgg tgtagctgga tggcttacat tagctattct tggtgctatt
     5941 atgccattta ttgttatgac tggaatgcat tgggcttttg cacctatttt tttggcggca
     6001 tctattgcta ctccagacgt attaattctt ccagcaatgt tagggtcaaa cttagctcaa
     6061 ggggctgctt cgatggctgt tgcattaaag agtaaaaata ataatacaaa acaaattgct
     6121 tttgcagcag gtttctcagc cttacttgca gggattaccg aacctgcatt atatggtgtg
     6181 actttaaaat ataaaaaacc gctttatgca gctatgattg gtggtggatt agcgggatta
     6241 tttgcaggtc ttactagtgt taaagcgtat ctatttgctg tcccatcttt gatagcgttg
     6301 cctcaattta tttattctga tgtaccatca aatattgtaa atgctttaat tgtggcggtt
     6361 atttcggttg ttattacctt tgtattagct tatatatttg gaatcgatga agaagagagt
     6421 tctagcaatt tagaagttaa agctggagtt tcaaataaaa aaatgatatt ttctcctata
     6481 tcaggagaaa tcattccgtt aagcgatgtc caggataaaa cattttcaga taaactaatt
     6541 ggagacggag tagcgattat cccaagtgaa ggtaaggttt atgcaccatt tgatgggaaa
     6601 attacaaata tttttccgac taagcacgca attggattga agagtgatga gggtgttgag
     6661 ttactaattc atattggatt agatactgtt gagctaaaag gtcaaggttt tattagtcat
     6721 gtagaagaag gagacagagt tttcaaaaat cagttgattt ttgaaatgga cttgaattta
     6781 atcaagacta aaggctacga aacagttaca ccagtaattg taacgaatac caatgatttt
     6841 ctagatgtat taatattacc taataatcag acaatcgagc attctaagga attactggta
     6901 atattataat ggaggaaagt tatgaccatt tttccagatg attttctttg gggtggagct
     6961 gttgcagcta atcaagtaga gggagcatat aatgaagatg gtaagggctt atcagttcag
     7021 gatgtgttac ccaaaggtgg attaggagaa gcaacagaaa atcctacaga agataactta
     7081 aaattgatag gtattgattt ttatcataaa tataaggaag atatatcctt gttttctgaa
     7141 atgggcttta atgtttttcg tacttctatt gcatggagta gaatttttcc aaaaggagat
     7201 gaggaagaac ctaacgaagc tgggttgaaa tattatgatg aattgtttga tgaactacat
     7261 gctcacggga tagaaccact tgtaactctt tcacactatg agactccatt atatttagca
     7321 agaaaatatc atggatggat tgataggaga atgattcatt tttatgaaaa atttgctcga
     7381 acagttttag aaaggtataa agataaagtt aaatattggc ttacatttaa cgaagtaaac
     7441 tctgttttgg aattaccgtt tactagtgga ggaatagata tacctaagga gaatctttcg
     7501 aaacaagaat tatatcaagc tatacatcat gaattagtcg cctcgagttt ggttacaaaa
     7561 attgctcgtg agattaattc agagtttaag gtggggtgta tggtattagc tatgccagct
     7621 tatccaatga ctccaaatcc aaaagatgta tgggcgactc atgagtatga gaatctaaat
     7681 tatctatttt cagatgtgca tgttagaggt tattatccga attatgcaaa aagatatttt
     7741 aaggaacatg acattaacat agagtttgca gctgaagatg cagagttatt aaaaaattat
     7801 actgtagatt ttttatcctt tagctattac atgagtgtaa ctcaatctgc tcttccaaca
     7861 cagtataatt caggagaagg gaatattatt ggtggtttag taaatcctta tttagagtct
     7921 tctgagtggg gatggcaaat tgatccaatt ggactacgta taattttaaa tagatattat
     7981 gaccgttatc aaattccatt atttatagtg gaaaacggat taggtgctaa agatcaacta
     8041 ataaaagatg aatttaataa cttaacagtc caagatgatt atagaattca gtatatgaaa
     8101 gaacatttat tgcaagtagc tgaagctcta caagatggtg tggaaattat gggctatacg
     8161 tcttggggat gtattgactg cgtttctatg tccactgcac agctttctaa gaggtacggt
     8221 ctcatttatg ttgatcgaaa tgatgatgga aatggcacat tcaatcgata taagaaaatg
     8281 tcctttactt ggtataaagg agtgattgaa tcaaatggag aatccttatt caaatagttt
     8341 gtttattgat gattagatat tatcacggtt aaggcagcat ctcattaaat atgaaataaa
     8401 gaggtttgga agacatcaaa ttctaaacct ctttatttta tagggggatt aattaattta
     8461 attttgttac agagagccga ttataaatag ttaacttagg atagattggt tatatatagc
     8521 agactgaatc taaaatagta cgaaacaatt gctaaaacat ttatagaaat taattttact
     8581 ttcccaatcg atttgttttc atcttatttc aatccgctat aaagttagat aagaataagc
     8641 taacaagcag aagtaagata ggtcttgcaa gaatggtaaa aatctgataa actaagtagt
     8701 aattgaatag gaatctgaaa gactagtagc ccaagggaag tatatcaggg aggagagccg
     8761 tgactgcaag ctctctatat gaaagctggg tgaattcact tgcgcatgga tttagaaatg
     8821 aaggtctgac ttgtcagatg aaaacggatg gtaccgcgtg tcaacgctcc gagtggagtt
     8881 tttggcatgt ggttttcttt ttatctacga gagactgatg gaggaaatat gtcaactatt
     8941 gaagaacaat taaaagcgtt tcgcgaagaa acgctggcta gcttgaagca gattactgct
     9001 ggaaatgaaa aagagatgca agatttgcgt gtctctgtcc ttggtaaaaa gggttcgctc
     9061 actgaaatcc tcaaagggat gaaagatgtt tctgctgaga tgcgtccaat catcgggaaa
     9121 cacgtcaatg aagctcgtga tgtcttgact gctgcttttg aagaaacagc taagctcttg
     9181 gaagaaaaga aagtcgcggc tcaactggct agcgagagta tcgatgtgac gcttccaggt
     9241 cgtccagttg cgactggtca ccgtcacgtt ttgacacaaa ccagtgaaga aatcgaagat
     9301 atcttcatcg gtatgggtta tcaagtcgtg gatggttttg aagtggagca agactactat
     9361 aactttgaac gtatgaacct tccaaaagac cacccagctc gtgatatgca ggatactttc
     9421 tatatcactg aagaaatctt gctccgtacc cacacgtctc cagttcaggc gcgtgctatg
     9481 gatgcccatg atttttctaa aggtcctttg aagatgatct cgccagggcg tgtcttccgt
     9541 cgcgatacgg acgatgcgac ccacagtcac caattcaacc aaatcgaagg cttggtagtt
     9601 gggaaaaata tctctatggc tgatcttcaa ggaacgcttc agttgattgt ccaaaaaatg
     9661 tttggtgaag agcgtcaaat tcgtttgcgt ccatcttact tcccattcac agagccatct
     9721 gttgaggtgg atgtttcttg cttcaagtgt ggtggagaag gctgtaatgt atgtaagaaa
     9781 acaggttgga tcgaaattat gggggccggt atggttcacc cacgtgtcct tgaaatgagt
     9841 ggtatcgatg cgactgtata ctctggcttt gcctttggtc ttggacaaga gcgtgtagct
     9901 atgctccgtt atggaatcaa cgatatccgt ggattctacc aaggagatgt ccgcttctca
     9961 gaacagttta aataatgatt agaaaagtag aaatggcaga tgttgaggtg ttggctaaaa
    10021 ttgccaaaca aacctttcgt gaaacctttg cgtatgataa tacggaagag cagttacagg
    10081 aatactttga agaggcttat agtctgaaaa ctgtgtcaac tgagttggga aatcctgact
    10141 ctgaaaccta tttcattatg catgaggagg agatagctgg ttttctcaaa gtcaactggg
    10201 gaagtgctca aactgagaga gaattagagg acgcttttga aattcaacgc ctctatgtgc
    10261 tacaaaaatt ccaaggattt ggactaggta agcaactgtt tgaattcgca cttgaacttg
    10321 ctacaaaaaa tagtttttct tgggcttggc taggtgtttg ggagcataat acaaaagctc
    10381 aagcctttta taaccgatat ggttttgaaa aatttagcca acatcatttt atggttggtc
    10441 aaaaagtaga tacggattgg ttactgagaa agaaattaag gtaagaagag gattcttcta
    10501 ttgaaatgat aggaaaggaa aagaaccagt gtggcaatgg tcattctgga gaactaaatt
    10561 atgcttgtat cttataaatg gttaaaagaa ttggtggaca ttgatgtgcc atcacaagag
    10621 ttggctgaaa aaatgtcaac tacaggaatc gaggtagagg gtgtcgaatc accagctgct
    10681 ggtctctcaa aaattgtcgt cggtgaggtc ttgtcttgcg aagatgtgcc agagactcac
    10741 ctccatgttt gtcaggttaa cgttggcgaa gaagaagagc gtcagatcgt ttgtggtgcc
    10801 ccaaatgtgc gtgctgggat caaggtcatg gtggctcttc caggagctcg tatcgctgat
    10861 aactacaaaa tcaaaaaagg aaaaatccgt ggtttggagt cacttggaat gatctgttca
    10921 cttggtgaat tgggaatttc tgactcagtt gtgcctaagg aattcgcaga tggcatccaa
    10981 atcttgccag aaaatgccgt gccaggtgag gaagtctttt cttacctaga cttggatgat
    11041 gaaatcatcg aactttccat cacaccaaac cgtgcagatg ccctttctat gtgtggagtg
    11101 gctcacgaag tggcagccat ctatgacaag gcagtcaact ttaaagaatt tactctaaca
    11161 gaaactaatg aagctgcggc agatgccctt tctgtcagca ttgggacaga caaggcgcct
    11221 tactatgcag ctcgtatctt ggacaatgtg actatcgcac caagtccaca atggttgcaa
    11281 aaccttctca tgaacgaagg catccgtccc atcaataacg ttgtagacgt gacaaactac
    11341 atcctgctct actttggtca acctatgcat gcttttgact tggacacatt tgaagggact
    11401 gacatccgtg tgcgtgaagc gcgtgctggt gaaaaattgg tgaccttgga cggtgaagaa
    11461 cgtgacttgg acgtgaatga cctagtcatc actgttgcag acaagccagt agcccttgca
    11521 ggtgtcatgg gtggtcaagc aacagaaatc tctgaaaaat ctagtcgtgt tgtccttgaa
    11581 gctgctgttt tcaatggcaa atctatccgt aagacaagtg gtcacctgaa ccttcgttct
    11641 gagtcatctt ctcgctttga aaaaggaatt aatgtggcaa cagttaatga agcccttgat
    11701 gcggcagcta gcctgattgc ggaacttgca ggtgcgacgg tgcgtaaggg tatcgtttca
    11761 gcgggtgagc ttgatacttc agatgtagaa gtttcttcaa ctcttgctga tgttaaccgt
    11821 gtcctcggaa ctgagctgtc ttatgctgat gtcgaagacg tcttccgtcg tcttggcttt
    11881 ggtctttctg gaaatgcaga cagctttaca gtcagcgtac cacgtcgtcg ttgggatatc
    11941 acaatcgaag ctgctctctt tgaagaaatc gctcgtatct atggatatga ccgcttgcca
    12001 accagccttc caaaagacga tggtacagct ggtgaattga ctgtgacaca aaaactccgc
    12061 cgtcaagttc gtaccattgc tgaaggagca ggtttgacag aaattatcac ctatgctctg
    12121 acaactcctg aaaaagcagt tgagttcaca gctcaaccaa gtaaccttac tgaactcatg
    12181 tggccaatga ctgtggatcg ttcagtcctc cgtcaaaata tgatttcagg gatccttgat
    12241 accgttgcct acaacgtggc tcgtaagaat aaaaacttgg ctctttatga gattggaaaa
    12301 gtctttgaac aaacaggtaa tccaaaagaa gaacttccaa atgagatcaa cagctttgcc
    12361 tttgccttga caggcttggt tgctgaaaaa gatttccaaa cagcagcagt tccagttgat
    12421 ttcttctatg ctaagggaat ccttgaagcc ctatttactc gtttgggact ccaagtaacc
    12481 tatacagcaa catctgaaat cgctagcctt catccaggtc gtacagccgt gatttcactc
    12541 ggtgaccaag ttcttggttt ccttggccaa gtgcatccag tcactgccaa ggcttacgat
    12601 attccagaaa cgtatgtagc tgagcttaac ctttcagcca tcgaaggggc gctccaacct
    12661 gctgttccat ttgtggaaat cacgaaattc ccagcagtca gccgtgacgt tgcccttctc
    12721 ctcaaggcag aagtgactca tcaagaagtt gtagatgcta tccaagctgc cggcgtgaaa
    12781 cgtttgacag atatcaaact ctttgacgtc ttctcaggtg agaaattggg acttggtatg
    12841 aagtccatgg cttatagctt gaccttccaa aatccagaag atagcttaac ggacgaagaa
    12901 gtcgcacgct atatggaaaa aatccaagca tcgctcgaag aaaaagtgaa tgcagaagtg
    12961 cgttaaacga tagtaggata caaattcccc ctctagttta tgaacactag agggggaatt
    13021 ttatataaaa taattaaaat gtgatttctg taaaaataca tctatgatca gagttttgaa
    13081 aacttacaat gtctaaatct ctaacatagt agtggttttt aggcaataag atatgatcta
    13141 tcgttgcatt aaaaagtttt ggactttggc tattccaagt tcctctttca aaaggtggaa
    13201 gtgcattcaa tgcgtcccta tgagagctta tttttgcaag tgctccatga cgcatagttg
    13261 cattaaaatc acctgcaata atagcctttg gatattttga agccaattga ttatgaatga
    13321 tgtttaagtc ttgcttccag atttccatta aacctggcag aggaggagca gtatgcaagg
    13381 caatgatatc tggtatattt tgttttctcg aatgtaatac aattgtcccg aaccgtgttg
    13441 tatgaaaagt tttagcttct gtatagaaac cataactttt cttgacaatc acagtcacag
    13501 gagctattcc actattggta ggtggagaag tgaaaatatc atagttggcc atagaaagtc
    13561 caacttgatg aaacaatagt ttgattctct ggttttcttg ctcacctctg atattggtag
    13621 ctagttcagg gaatatagcc atatcggcgt caaaatggct aaaaattcgc tcaatatgtt
    13681 gtgcttctat ttgattagcg acgttccaag ttactaattt taaggtttta gtcttatttg
    13741 atgcagaaga aagggtttta tctgttccga ataatagtaa tatgagcgat agtaagagca
    13801 aaatgccaga gtaaaaccgt atttgtttat ttttcttgta aaaagatagg aaaaaaaata
    13861 agaaacttaa aatagcagcc atagttgcag tagctaaggg gaaggcataa atctgtgcca
    13921 agataggttg ggtagatagc caaatgttaa gattagaaga tgggaaaaaa gaataagtta
    13981 tgatagggat agaaaagaga atgaccgaaa gggcagagag aaatgtttta atcattgtgt
    14041 gagtacctca atttgcaatg gttgctcgga gctaatgtaa ctttgtgact ttacttgatt
    14101 gatattcttt ttcttgtctt cctcatagat taagtacaac ccaagtaaaa aaagtccaat
    14161 ttaagattga aatgattaaa aggcacagaa atgcaagaca attatactac aaaaggcaaa
    14221 catttgacaa tcgatagccg tcgcttaatc gaacgatgga aaaaagaagg aaaatcaaat
    14281 agagaaattg cctctctact tggaaaagct cctcaaacta tccatactga aatcaagtat
    14341 gggacagtcc gacaatgtct tggaaaaggg cgcttcaaag agatttattc tgccgactac
    14401 gctcaacagt cttatgaaaa taatcgcaag cactcggtca agaaatcaag cttgactaag
    14461 aaactaaagg aaaagattct ccactatcat aaccaaaaat tttcgcctga aatgatggtg
    14521 atggctaaag gggttaacgt gggaatttca accatttact attggattca tcgtggaaaa
    14581 ttggggttaa gcaagcagga tctgctttat cctagaaaag gaaaagcgct taagaaatag
    14641 gctagcacca actttaaacc cgctggtcaa tctatcgaat cataattcgc tcattttttt
    14701 aaaaatacat agacgtaaaa aaaagagggt taagtgatga agaatagtgc tattgggagt
    14761 aattggaagg atgtccatct gagctcttta gcaaggagga aatccttgaa agtgatatgc
    14821 gagtggctat catgagcgag ttgattgagg ctaggtatga acaaggaatc agtcagaaaa
    14881 agctggaaga agtcagtgga ataagccagc ctgtcatagc taggatggag acaggagaga
    14941 gcagtcttca gttggatacg gtcttaaaag ttctaaccag tctaggaaag acactagcag
    15001 tcgttccact tgaacagggg aaaagttgac tagaatcagt tatagtcttt tctaataaca
    15061 ggtcatagtc acttataaga attactaata acatgtttta gtattctaat tggaatatag
    15121 ctgtaaagta agaattacaa aggatttgag acgtttgctt caagtctttt tcttttgtcc
    15181 gaaacagata tatagtttca aactatatca aaccctaatt ttttacaatt atacagacgc
    15241 tttcttttct gttaagatag tttcaacaac aaattttgga ggacacatca tgtcaactac
    15301 aatcatcggt ttccctcgtt tgggcgaatt ccgtgaatta aaatttacaa ctgaaaaata
    15361 ctttagaaaa gaaatctcag aagaagaact tttagcagca gcaaaagact tgcgtgctaa
    15421 acactggaac attgtcaaag aaaaaggcat cactgaaatt ccatcaaatg acttttctca
    15481 ctatgataac ttcctagatg cggctttcct tttcaacgtg gtgcctgcat ccgttcaaaa
    15541 cttggacttg tctgaccttg agcgctactt cgctttggga cgtggttacc agggagaaaa
    15601 aggggacgtt cgcgcccttc caatgaagaa atggttcaac actaactacc actacatcgt
    15661 tcctaaattt gaaaaagaca ctcaagtaaa attggctggt cacaagattt tcgatgagtt
    15721 ccaagaagca aaagaacttg gattgaacac tcgtcctgtt cttgtaggtc cattcacttt
    15781 ccttcaattg tcagactttg aagaaggcgt gaaagcagac gacttcgtag atagcttagt
    15841 ggttgcttac caagaagttt ttgctaaatt ggctgaactt ggtgcgactc gcatccaatt
    15901 ggatgaagcg gctcttgtaa aagacttgac agctgaagaa aaagctctct tcttgaacct
    15961 ttacaacaaa ctcttggctg acaaaaaagg tcttgaagtc ttgcttcaaa cttatttcgg
    16021 tgatgttcgt gacgtatacg ctgaccttgt aaacttgcca gtagatgcta tcggtcttga
    16081 ctttgttgaa ggtaagaaaa ctcttgaact cgttaaaggt ggcttcccag ctgacaagac
    16141 tctctatgta ggtattgtca atggtaaaaa catctggcgc aacaactacg aaaagagctt
    16201 ggctgttctt gagcaaatcc cagctgaaaa catcgttttg acaagctctt gctcacttct
    16261 tcatgtgcca tttacaactg ctaatgaaga atttgaacca gcactcttga accactttgc
    16321 ctttgcagtt gaaaaattgg atgaaatccg tgacttggat gctatccgca atggtcaagg
    16381 ttcagaagct cttgcagcca acaaagaact ctttgcgact gagcgtgttg gtgaaaatgc
    16441 tgaacttcgt gcgcgtatcg ctggcttgac agacgcagac tacactcgtt tgccagcctt
    16501 tgcagaacgt gaagctatcc aagaagaagc tttcaaactt ccagctcttc caacaacaac
    16561 gattggttca ttccctcaaa caaaagaagt tcgtgccaaa cgtttggctt accgtaaagg
    16621 tgaattgtct caaaaagagt acgatgcttt ccttgctgaa acgattgacg aatggatcaa
    16681 gtggcaagaa gatattgact ttgatgtcct tgttcacggt gaatttgagc gtaatgacat
    16741 ggttgagtac ttcggtcaaa acttgtcagg atacctcttc tctaaaaatg gatgggtaca
    16801 atcatacggt atgcgtgggg taaaaccacc aatcatctgg ggtgatgtca ctcgtcttaa
    16861 ccctatcact gttaaatggt ctagctatgc acaaagtcgt acaaacaaac ctgttaaagg
    16921 tatgttgact ggacctgtta ccatccttaa ctggtcattc ccacgtgaag acatctctat
    16981 caaggattca actcttcaaa tcgcccttgc tatcaaggat gaagtacttg accttgaagc
    17041 tgctggtgtg aaaatcatcc aaatcgacga ggctgctctt cgtgaaaaat tgccactccg
    17101 ccgtagcgac tggtacgaag actaccttga ctgggctatt cctgccttcc gcttggtaca
    17161 ctcaacagta gcgccagaca cacaaatcca cactcacatg tgttactcag aatttacaga
    17221 tatcatccca gctatcgata acatggatgc agacgttatt tcctttgaag ctagccgttc
    17281 aaaccttgaa atcttggacg aactcaaagc gaaaaacttc caaacagaag tgggacctgg
    17341 ggtttacgat atccactcac ctcgtgtacc aaatgaaggc gaaatcgaca acacaatcga
    17401 agccatcctt gctaaagtgc caagcaagaa agtttggatc aaccctgact gtggtttgaa
    17461 aacacgtggt atcccagaaa caaaagaaag cttgatccgc cttgttgaag cagctaaagc
    17521 tgcgcgtgag aaattgtaag attggatttc tctccataca gtggttgttc aaaaagaaat
    17581 caactagaaa aggttattac atatgtcacg ccaaacaccg tcactctcat ttgaagtgtt
    17641 ccctccaaac ccagccgtgg gtaatggtaa cattatttca gccttgcagg atatgcagga
    17701 gttggctccc cattttatca gtgtaactgc cagcaataat aaatttaata tcaaggaaac
    17761 gacggttcgt ttggctgact ttatccaaaa tgatttggcg attccgacca ttgcccactt
    17821 gccagctatt tatctaacta aggacaaggt tgctgaaact attgctgact tggacaaagt
    17881 tggggtgcag aaaatcttgg ctcttcgtgg ggatattatt ccagacgtgg aaccacaaaa
    17941 ggatttccgc tatgcaaccg acttgattga gtttatcaag gaacaaaccc ctcgctttga
    18001 tattattgga gcttgctatc cagaagggca tccagattcg ccaaatcaga tttcagatat
    18061 tcaaaatctt aagaagaaag tggatgcagg ctgttcgagc ctcgtaactc agctcttctt
    18121 tgacaatgag cgcttctatg attttcagga caagtgcatc ttggctggga ttgatgttcc
    18181 cattcatgca ggaattatgc caattctgaa tcgaaatcag gctctccgac tcttgaagac
    18241 ttgtgagaat atccatcttc cacgcaaatt taaagccatc ttagacaagt atgagcatga
    18301 ccctgagtcg ctcagagcag caggacttgc ctatgcagtg gaccaaatcg tggacttggt
    18361 aactcaggat gttgccggtg tgcatctcta tacgatgaat aatgctgata cagcaaaata
    18421 catccatcaa gcaacccatg ccttgtttaa tcaccagtct ctaggataat aaaagcaaac
    18481 cattcttctc aggtgagggg aatggttcct ttttaatggt aaagacctca ctttttaaga
    18541 aaaatatgat aaaataaatt ctgtacgtac ttgatacaaa gatgaaggta ttaaataata
    18601 caatgcattt aaactgtaag atttaacgac acgagtgagt caaatcgatg ttatttgacg
    18661 agagagttag taaagcattt agctaatcgc ccgatagcga ttagcgtgaa agctttagat
    18721 actttagtat taaacctttc taatgatgta tcttgaaaac tgaacttgcc tacaactctg
    18781 tggaaaaaga taaatctccc taggagcagt cgctccgtcg ttcgatttcc tat
//
LOCUS       DAVDHZ010000041        18771 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000041 DAVDHZ010000000
VERSION     DAVDHZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18771
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.042"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            159..614
                     /locus_tag="VUR46_001724"
                     /pseudo
     CDS             159..614
                     /locus_tag="VUR46_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            767..1063
                     /locus_tag="VUR46_001725"
     CDS             767..1063
                     /locus_tag="VUR46_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET5457103.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYK"
     gene            1269..3014
                     /locus_tag="VUR46_001726"
     CDS             1269..3014
                     /locus_tag="VUR46_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457104.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            3004..4755
                     /locus_tag="VUR46_001727"
     CDS             3004..4755
                     /locus_tag="VUR46_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457105.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            4928..5620
                     /locus_tag="VUR46_001728"
     CDS             4928..5620
                     /locus_tag="VUR46_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET5457106.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLAFVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            5663..6889
                     /locus_tag="VUR46_001729"
     CDS             5663..6889
                     /locus_tag="VUR46_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET5457107.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKIVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            8020..10179
                     /gene="pfbA"
                     /locus_tag="VUR46_001730"
     CDS             8020..10179
                     /gene="pfbA"
                     /locus_tag="VUR46_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET5457108.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNYKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGREAENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            10707..11021
                     /locus_tag="VUR46_001731"
                     /pseudo
     CDS             10707..11021
                     /locus_tag="VUR46_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            11201..11860
                     /locus_tag="VUR46_001732"
     CDS             11201..11860
                     /locus_tag="VUR46_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET5457109.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVSYHEKF
                     K"
     gene            11885..12952
                     /locus_tag="VUR46_001733"
     CDS             11885..12952
                     /locus_tag="VUR46_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5457110.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELASKYKGQYSIYGLTGGTGRAIYASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            13055..14065
                     /locus_tag="VUR46_001734"
     CDS             13055..14065
                     /locus_tag="VUR46_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457111.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            14077..15768
                     /locus_tag="VUR46_001735"
     CDS             14077..15768
                     /locus_tag="VUR46_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET5457112.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            15771..16481
                     /locus_tag="VUR46_001736"
     CDS             15771..16481
                     /locus_tag="VUR46_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET5457113.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            16577..16768
                     /locus_tag="VUR46_001737"
     CDS             16577..16768
                     /locus_tag="VUR46_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457114.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKNNSILKC"
     gene            17053..18054
                     /locus_tag="VUR46_001738"
     CDS             17053..18054
                     /locus_tag="VUR46_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5457115.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         5968 a         3056 c         3767 g         5980 t
ORIGIN      
        1 caatattcca tgagataagt ttcataaagt tacctttttc attcagatta tagattttat
       61 tataccaaaa aaagatctat ttccccaacg tatagtttga aaaattactc tctttcgttt
      121 ataattaaga atgattttat gaaagggagt gaaaacacat gaaattctac tcttatgact
      181 atgtactcag ccaaatcggt cagcaaaatg gtatcatggt tggctttggg attgttctat
      241 tagctgtgac agtttttttg cttttaaggt ataccatgat aaaaagggaa ccgaatttcg
      301 tgagttggtc atgatttcag ctctggcctt atttagctct gcttttggtc agcatcacga
      361 cttatcaaaa caatcaagtt tctaacaata aatttcaaac ttcacttcat ttcatcgagg
      421 ttgtttccaa agatttggga gtagacaagt cagaagtcta tgttaatact tccacaaaca
      481 cagatggcgc acttatcaag gtgggagaac gctattatcg tgccctaaac ggaagtgagc
      541 cagacaagta cctgttagag aaagtcgaat tgtataagac agacgcaatt gaactggtgg
      601 atgtgaacaa atgacactta attatatcga aattttaatc aaactggtct tgactctcaa
      661 atagctcaac aacaatgttc actttgtgaa acgtttgatt gatggtaagc caactctcct
      721 tatcaaaaat gggaatattg acccataagc ctgtcgttca gttggtttgt ctgcatcgga
      781 tgtagccctc aaacttcgta gccaagggat tttccagatg aagcaagtca aacgagctgt
      841 gcaagagcaa aatgggcaac tcatcgttgt gcaaatggga gatgaaaatc ctaagtatcc
      901 agttgtgact gacggtgtga ttcaagtaga tgtcttggaa tcgattggtc gtagcgaaga
      961 gtggttgctt gataacctca gtaaacaagg gcatgacaat gtagccaata tctttattgc
     1021 tgaatatgac aagggtgctg ttacagtcgt aacttataaa taagaaaaac ctggggtctt
     1081 gtactcttcg aaaatctctt caaaccgcgt caacgtcgcc ttgccgtatg taggttactg
     1141 acttcgtcag ttctatctac aacctcaaag cagtgctttg agcagcctgc ggctagtttc
     1201 ctagtttgct ctttgatttt cattgagtat tggcctcagg tttccatttg caatcagaaa
     1261 gggattttat gtccattatt caaaaactct ggtggttttt caagttagaa aaacgccgtt
     1321 atctagtcgg gattgtggcc ctggtcttgg tttccgtcct caatctcatt cctcctatgg
     1381 ttatggggcg agtcattgat gccatcacat cggggcaatt aactcagcag gacctccttc
     1441 ttagcctatt ttacttgcta cttgcagcct ttggtatgta ctatttgcgc tatgtgtggc
     1501 gtatgtatat ccttgggacc tcttattgct tgggacagat catgcggtct cgcttgttta
     1561 agcatttcac aaaaatgtca tcagcctttt atcaaaccta tcggacgggt gatctgatgg
     1621 cacacgcaac caatgatatc aatgccttga ctcgtttagc aggtggcggt gtcatgtctg
     1681 cggtggatgc ctctatcacg gctctggtga ctttgttgac catgctcttt agcatctcat
     1741 ggcagatgac tcttgttgcc attctccccc tacctttcat ggcctatgcg actagtcgcc
     1801 tagggagaaa gactcataag gcctttggcg aatcccaagc tgctttttct gaactcaata
     1861 acaaggtaca ggagtccgta tcaggtatca aagtgaccaa gtctttcggt tatcaggcag
     1921 acgagttgaa gtcttttcag gcagtcaatg aattaacctt ccaaaagaac ctgcaaacca
     1981 tgaaatatga tagtctcttt gaccctatgg ttctcgtgtt tgttggttcg tcctatgttt
     2041 taacgctttt ggttggctcc ttgatggttc aggaagggca gattacagtt gggaatctag
     2101 tcacctttat cagctatttg gatatgctgg tctggcctct tatggccatc ggcttcctct
     2161 ttaatactac tcagcgaggg aaggtttctt accagcggat tgaaaatctt ttgtctcagg
     2221 aatctcctgt acaagaccct gagtttcctc tggatggtat tgaaaatggg cgtttggagt
     2281 atgccattga cagctttgct tttgaaaatg aggaaacact gacggatatt cactttagtt
     2341 tggcaaaagg gcaaacactg ggcttggttg ggcagacagg ctctgggaaa acgtccttaa
     2401 tcaagctcct cttgcgtgaa tacgatgtgg ataagggtgc catttatcta aacggtcacg
     2461 atattcggga ctatcgtctg acagaccttc gcagtctcat gggctatgtt cctcaggacc
     2521 agtttctttt tgcgacttca atcctagaca atatccgctt tggcaatcct aacttgcccc
     2581 tttcagcggt cgaggaagct actaagctag cccgggttta ccaagatatt gtagacatgc
     2641 ctcaaggatt tgatacgctg attggtgaaa aaggagtcag tctttctggt ggtcaaaagc
     2701 aacggttggc tatgagtcgg gctatgattt tagaccctga tatcttgatt ttggatgatt
     2761 ccttatccgc cgtagatgcc aagacagagt atgcgattat cgacaacctc aaggagacgc
     2821 gaaaggacaa gacaaccatt atcactgccc atcgcctcag tgctgttgtc catgcagatt
     2881 ttattttagt tctacaaaat ggtcaaatta tcgaacgagg cacgcacgaa gacttgctag
     2941 cgatggatgg ctggtatgcc caaacctacc agtctcagca gttggaaatg aaaggagaag
     3001 aagatgcaga ataaacaaga acaatgggct gtattgaagc gcttgatgtc ttatctcaag
     3061 ccttatggac tcctgacctt tttggcactc agttttctcc tagcgacgac ggtcattaaa
     3121 agtgtcatac ccctcgtggc ttcccacttt atcgaccagt atctcagcaa tcttaaccaa
     3181 ctagccgtta ccgttttgct ggtctactat ggtctctaca tcctacaaac tgtagttcag
     3241 tatgtgggca atcttctctt tgcgcgcgtg tcttatagta ttgttaggga tattcgtcga
     3301 gatgcctttg ctaatatgga gaaactgggc atgtcttact ttgacaagac gccagcaggt
     3361 tctatcgttt ctcgtttgac caacgatacc gagacgatta gtgatatgtt ttctgggatt
     3421 ttatccagct ttatctcagc agtttttatc tttctgacaa ccctttatac catgttggtg
     3481 ctggattttc gtttgacggc tttagtcttg ctctttcttc ctttgatttt ccttttggtc
     3541 aatctctatc gaaaaaagtc agtgaaaatc atcgagaaaa ccagaagtct cttgtcagat
     3601 atcaatagta agctggcaga gaatatcgag ggaatcagga ttattcaggc ttttaatcaa
     3661 gagaagcgcc tgcaggcaga atttgatgaa atcaaccaag agcacttggc ctatgccaac
     3721 cgttctgtag ccttggatgc cctctttttg agacctgcca tgagtttgtt gaaacttcta
     3781 ggttatgctg tcttgatgac ctattttggc tatcgtggtc tttctatcgg gataacggcc
     3841 gggaccatgt atgcttttat ccagtacatc aaccgcctct ttgacccttt gattgaggtg
     3901 acgcaaaact tttcaacact gcaaacgtct atggtttctg caggccgtgt ctttgcctta
     3961 atcgatgaga ggacctatga gcctcttcaa gaaaatgggc aagccaaagt caaagaaggc
     4021 aatatccgtt ttgaacatgt gtgtttctcg tatgacggta aacatccgat tctggatgac
     4081 atttctttct ctgttaataa gggtgaaacc attgcctttg taggtcatac aggttcaggg
     4141 aaatcgtcta ttatcaatgt cctcatgcgc ttttatgaat tccagtcagg gagagttctc
     4201 ttggatgatg tggatatcag ggatttcagt caagaagagc tgagaaaaaa catcggtttg
     4261 gttttacagg aacccttcct ctatcatgga actattaagt ccaatatcgc catgtaccaa
     4321 gaaatcagtg atgagcaggt tcaggctgcg gcagcctttg tggatgcaga ttcctttatt
     4381 caagaacttc ctcaggggta cgactcccct gtttccgagc gtggttcgag cttctctact
     4441 gggcaacgcc agctccttgc ctttgctaga acagtcgcca gccagcctaa aatcctgatt
     4501 ttggatgaag cgacagccaa tattgactct gaaacagaaa gcttggttca agcttctctg
     4561 gcgaagatga gacagggccg aacaactatt gctatcgctc accgcctttc tactattcaa
     4621 gacgccaact gcatctatgt cttggataag ggacgcatta tcgagagtgg aacccatgag
     4681 gaactcttga ctctgggagg aacctatcac aagatgtata gtttgcaggc aggggccatg
     4741 gccgatactc tttgaaaatc tctttaaacc atgtcagctt tatctgcaat ctcaaagctg
     4801 tactttgatt ttcattgagt actagaagga aatccttcaa attacagatt tctttcaccg
     4861 ccttttccat tttgtggtat aatgaaaaat gttgacaaat agtataataa aaacaaagga
     4921 gaacagcatg ctgaaatggg aagacttgcc tgtggaaatg aaatcaagcg aggttgagtc
     4981 ttattaccag cttgtctcta aaaggaaggg ttcgctgatt ttcaagcgtt gcttggactg
     5041 ggttctagcc tttgtcttac tggttctgac ctctcccatc tttctcatct tgagcatttg
     5101 gatcaagttg gatagcaagg ggccagtgat ttacaagcaa gagcgtgtga cccagtacaa
     5161 ccgtcggttc aagatttgga agttccgtac catggtgacg gatgcggata aaaaaggaag
     5221 tctggtgact tctgctaacg atagccgtat taccaaggtt ggaaatttca tccgacgtgt
     5281 ccgtttggac gaactgcctc agttggtcaa tgtccttaaa ggtgagatgt cctttgtcgg
     5341 tacacgacct gaagtgccac gttatacaga gcagtatagc cctgaaatga tggcaacctt
     5401 gctcttgcaa gcaggaatta cctctccagc cagcatcaac tacaaggatg aggacaccat
     5461 catcagtcaa atgacggaga aaggtctgtc agttgatcag gcctatgtgg agcatgttct
     5521 tcctgaaaag atgcgctata acctcgccta tctccgagag tttagtttct ttggggacat
     5581 caaaatcatg tttcaaaccg tgtttgaggt actaaaataa agtagtcata agaaaatgag
     5641 tacagataaa aggagcaaat caatgccaaa ttacaatatt ccattttcac cgcctgatat
     5701 cacagaagca gaaattgctg aagtagcgga taccctgcgt tctggttgga tcacaacagg
     5761 tcctaaaaca aaagaactgg agcgccgctt gtctctttac acacagacac ctaagattgt
     5821 ttgtctcaac tctgcgacag ctgctctgga gttgatttta cgcgttttgg aagtgggacc
     5881 tggtgatgaa gtcatcgttc cagccatgac ctatacggct tcatgtagtg tcattacgca
     5941 cgtgggagca acccctgtca tggtggatat ccaagcagat acgtttgaga tggactatga
     6001 cctgcttgag caagctatca ctgagaaaac taaggtgatt atcccagtag agctcgcagg
     6061 gattgtttgc gattatgacc gtttgttcca agtcgtggag aaaaaacgtg acttctttac
     6121 cgcttcaagc aagtggcaaa aggcctttaa ccgtattgtc attgtctctg atagtgccca
     6181 cgctttggga tctacttata aaggacaacc ttctggttct atcgctgact ttacttcctt
     6241 ctcattccat gccgttaaga actttacaac ggcagaaggt ggaagtgcga cttggaaagc
     6301 caatccagtg attgatgacg aagagatgta caaggaattc caaatccttt cccttcacgg
     6361 gcaaactaag gatgctcttg ccaagatgca actggggtca tgggaatacg atatcgttac
     6421 accagcctat aagtgcaaca tgaccgatat catggcttca cttggtttgg tacaattgga
     6481 ccgctatcca agtttgttac aacgccgtaa ggacattgtg gaccgctatg atagtggttt
     6541 tgcaggttct cgcatccatc ctttggcaca caagactgaa actgtcgaat cttcacgcca
     6601 cctctacatc acccgtgtag aaggagcaag cctagaagaa cgcaacctca tcatccaaga
     6661 attggctaaa gcaggaattg caagtaatgt tcactacaaa ccgcttcctc tcttgacagc
     6721 ctataagaat cttggatttg atatgacgaa ctatcctaag gcctatgcct tctttgagaa
     6781 tgaaattacc ctccctcttc atactaaatt aagcgatgaa gaagtagact atatcattga
     6841 gactttcaaa acagtttctg aaaaagtgct aactttatca aaaaaatgac aaactacagt
     6901 caagcgaaag tgatcctgtc cttaaaaagt ctaattgagt gtaaaaactg ttgttttcaa
     6961 ttgataatag tttacacctg tagttgaggc tcctttctcc tcagagagag aatttttata
     7021 ggattttcct ttcttgtggg agtcccgtgg tttgaaataa gatgtgagca atttggtgta
     7081 gcatttagaa tccttactag acatcattta gaaaatctag tgtcttgttc tagttttcaa
     7141 ttcaccctat tttttgaaag acgtgagttt ccatgagtga gattgtggaa actcgcgtct
     7201 tttttttgtt ttcagaatat tgttcaaagt tttgtgcctg tctttcatgt tctagtcatt
     7261 cttttacatg atagaattta tagcatgttg atattataat aatacgaata tcccatatgt
     7321 ttagtgatgc ttgctataca tcattagatc tcctgcgaga caatctataa aacacttgtc
     7381 tacgattacc tatatgccct attccagtat tttagaagca ctgcatctat ttttatcgag
     7441 gttaaatcta gcttttatag aaggtctatt taagaaatat attgtagtgt tttagtttca
     7501 atccgccata tgagcgatat taaggtaaat atccctggcg aatgcttgta tgacaaggta
     7561 tttgttcttt catttataat ttacaacata tcaataaatt taaatatagt aaatgggata
     7621 ttttatattc aagctaagaa agatagcatc acttttgaat ggaaggctaa agagcaaact
     7681 aggaagttgg ccatagatag ctcaaaaccc tgctttgagg ttgtagatat agtaaaagga
     7741 aataagaata ggacaaatcg atcgggacag tcaaatcgat ttctaacaat gttttagaag
     7801 tagaggtgta ctattatagt ttcagtctac tatagaactg accaagtcag taacctagac
     7861 ttagggcaag gcggcactga cctagtttga agagatttcc gaagagtata aattttaata
     7921 ttttcttgtg ttattccttg acaattcaat ttggaaaata tatgataaag ataatgacag
     7981 cggtgtcatt ctatctattt taagaaaagt aataatcaat tgttaaaaat agtaaaaaaa
     8041 ttggaggttc tgatgaaata ttttgttcct aatgaggtat tcagtattcg taaattaaag
     8101 gtggggactt gctcggtact attggcaatt tcaattttgg gaagccaagg tattttatcg
     8161 gatgaagttg ttactagttc ttcaccgatg gctacaaaag agtcttctaa tgcaattact
     8221 aatgatttag ataattcacc aactgttaat cagaatcgtt ctgctgaaat gattgcctct
     8281 aattcaacca ctaatggttt agataattcg ttaagtgtta atagcatcag ctctaatggt
     8341 actattcgtt ccaattcaca attagacaac agaacagttg aatctacagt aacatctact
     8401 aatgaaaata agagttataa ggaagatgtt ataagtgaca gaattatcaa aaaagaattt
     8461 gaagatactg ctttaagtgt aaaagattat ggtgcagtag gtgatgggat tcatgatgat
     8521 cgacaagcaa ttcaagatgc aatagatgct gcagctcaag ggctaggtgg aggaaatgta
     8581 tattttcctg aaggaactta tttagtaaaa gaaattgttt ttttaaaaag tcatacacac
     8641 ttagaattga atgagaaagc tacaattcta aatggtataa atattaagaa tcacccttcc
     8701 attgttttta tgacaggttt atttacggat gatggtgcgc aagtagaatg gggcccaaca
     8761 gaagatatta gttattctgg tggtacgatt gatatgaacg gtgctttgaa tgaagaagga
     8821 actaaagcaa aaaatctacc acttataaat tcttcaggtg catttgctat tgggaattca
     8881 aataacgtaa ctataaaaaa tgtaacattc aaggatagtt atcaagggca tgctattcaa
     8941 attgcaggtt cgaaaaatgt attagttgat aattctcgtt ttcttgggca agccttaccc
     9001 aaaacgatga aggatgggca aatcataagt aaggagagca ttcagattga accattaact
     9061 agaaaaggtt ttccttatgc cttgaatgat gatgggaaaa aatctgaaaa tgtgactatt
     9121 caaaattcct attttggcaa aagtgataaa tctggggaat tagtaacagc aattggcaca
     9181 cactatcaaa cattgtcgac acagaacccc tctaatatta aaattttaaa taatcatttt
     9241 gataacatga tgtatgcagg tgtacgtttt acaggattca ctgatgtatt aatcaaagga
     9301 aatcgctttg ataagaaagt taaaggagag agtgtacatt atcgagaaag cggagcagct
     9361 ttagtaaatg cttatagcta taaaaacact aaagacctat tagatttaaa taaacaggtg
     9421 gttatcgccg aaaatatatt taatattgcc gatcctaaaa caaaagcgat acgagttgca
     9481 aaagatagtg cagaatattt aggaaaagta tcagatatta ctgtaacaaa aaatgtaatt
     9541 aataataatt ataaggaaac agaacaacca aatattgaat tattacgagt tagtgataat
     9601 ttagtagtct cagagaatag tatattcggt ggtaaagaag gaattgttat tgaggattca
     9661 aagggtaaaa taaccgtttt aaataaccaa ttttataatt tatccggtaa gtatatatca
     9721 ttcatcaaat ctaatgcaaa tgggaaagaa cctgttatac gtgatagcga tggtaatttc
     9781 aatattgtaa cggagaatgg gctttacaaa attgtaacaa ataatttaag tgataaaaac
     9841 gaaaaagaaa aaaacaaaga ggaaaaacaa tctaattcaa ataatgtaat tgatagtaac
     9901 cagaagaacg gagagtttaa ctcaagtaaa gataatagac aaatgaatga caagatcgac
     9961 aataaacaag ataataagac agaagaagta aactataaaa tagttggaga tggcagagaa
    10021 gctgaaaatc atattaataa atctaaagaa atagtagatg taaaacaaaa attaccaaag
    10081 actggttcga acaagattat ggaactattc ttaacagtga caggaattgg tttacttttg
    10141 acactaaaag ggttgaagta ttatggtaaa gataaataaa atttgttcga ttacaaggaa
    10201 gttccgtaga aaatgaggat attgtaggtt cacaaaatca gtatttttgg attattggtg
    10261 gagctacaga tttatataat tctaaagagg agataggtta ttcagtctca gaagttgtac
    10321 atattttatc agaaagtttg tcggttaatt gtaaagaatc aaaaactctt aaacaaatat
    10381 ttgaaactgc tttactcgag gttaaagatg aaatcggttt aaactcatat gaattaacag
    10441 agtatagtaa aatgaaataa taataggaca aatcaatcag gacagtcaaa tctattttta
    10501 acaatgtttt agaagtaggg gtgtactatt ctagtttcaa tctactatat tatcgcttac
    10561 caacatttgc ttttatattt gctaaacttt cagaaaaaag ttggagtata tgatgctagg
    10621 tgattgcgtc atgttagtaa acgaaatgga aataactgat catagagtag ataacttatt
    10681 tgaaaaaggg aaaaatgaga taaaagatcc atgtagtaga tttagcaata ggacatataa
    10741 aagctttaga aaaagtatct gaaaaaacag atgtttatat ctataaccta tgctcgggag
    10801 aaggcactag tgtattacaa cttgtaaata catttgaaag tgttaataag atctctattc
    10861 cttataaaat agttccaaga cgttcaggag acgttgcaac ttgttatgca aatgcagaca
    10921 aagcatataa ggaattaaat tggaggacaa caaaatcgat tgaagacatg tgtagagata
    10981 catggaattg gcaatcaaaa aatcccaatg actataattg atgatactgt ctatatgagt
    11041 gctgtatttt ggaaaaatta cttaaccttt taatgaaatg catatttaat gaaagataaa
    11101 ttaaaaaaaa tgtttgacag cgcttgacaa aggaaacggt ttcattgtat aatgtaaaca
    11161 tagtgacacc gatatcaaat ataaaaaaga aggtctttat atgaaaaact taacaaaaat
    11221 taagttcaaa gagaatgggg aatttaatca tttccctggg aatacagttg tagcaaatct
    11281 ttatactaaa caagatttga tggaagttgt tgatattatt caatcacgtt atagagaatt
    11341 accatttatc gataagttta ctttaactcc aaggaattct attcacatga ctgtaattga
    11401 attgttgtgc catgaaaatc gtgaaacgga gttttggagc agtaatcttc ctctagatac
    11461 acctttacag gaaatacatg attactttgc taaacaactt gaaatttttc cattgttgga
    11521 tgaagaaatt catatgcgtg taactgaaat gggaaaacaa aacatactag ttgaacctgc
    11581 agatgaagct tctgcaaaga gattagaaga aattcgtact tatgtctcag aaaaagcagg
    11641 tgttcgtttc cctaatcatg atagatatca attccatatt tcaattgggt atcttcggat
    11701 tcctctaacc gaagaggagg aagaagagtt tactaaagtc agagcagaat taactgaaat
    11761 tttattagag aagattccaa ctattactgt aaaccgtatt gactatactg tatttgaaga
    11821 tatgagacaa tttgtttcat atcacgaaaa atttaaataa aataataaaa aaggagaact
    11881 tatcatgaaa aaaatgaaag tttggtctac tgtacttgca acgggagttg ctcttactac
    11941 acttgctgct tgctctggag gttcaaattc tacgactgct tcttcatctg aagaaaaagc
    12001 tgataaaagt caagaattag ttatctattc gaactcagtc tcaaatggtc gtggtgattg
    12061 gttaactgct aaagcaaaag aagctggttt taatataaaa atggttgata tcgctggcgc
    12121 tcaattagca gaccgtgtta ttgctgagaa gaataatgca gttgcagata tggtatttgg
    12181 aattggtgct gttgactcaa ataaaattag agatcaaaaa ttactagtac agtacaagcc
    12241 taaatggtta gataaaattg atcaatcttt atcagataaa gataattatt ataacccagt
    12301 tattgttcaa cccttggtat tgattggagc tcctgatgca aaagaaatgc caaaagactg
    12361 gacagagtta gctagtaaat ataagggaca atattccatt tatggcttaa ctggtgggac
    12421 tggacgcgcc atttacgcaa gtattctagt tcgttatctt gatgaaaaag gtgatttagg
    12481 agtatcggaa aagggctggg aagttgcaaa agaatacttt gcaaatgcct atactcttca
    12541 aaaaggtgaa agctcagttg ttaaagcgtt agataaagaa agcccaattc aatacggtat
    12601 gatctggggt tctggagcgt taattggaca aaaagaacaa aatgttgaat tcaaagttat
    12661 gactcctgag attggtgtac catttgtaac tgaacaaact atggttttaa gcactagtaa
    12721 aaaacaagcg ttagctaaag aatttattga ttggtttggt caatcagaaa ttcaagtaga
    12781 atatagtaaa aaatttggct ctatccctgc caataaagat gccctaaaag agttacctga
    12841 agatacgaaa aaatttgttg atcaagtgaa accacaaaat attgactggg aagctgttgg
    12901 aaagcatttg gatgaatggg tagaaaaagc tgaattagaa tacgtaaaat aagaaataag
    12961 agttattttt tatgtccaag tctctctatt atttctaaat ttaaggaaga aataaagaga
    13021 ggcttttggt ttagtaatag agggagttag tgagatgatt aaatttgata atattcaaat
    13081 taaatatggt gattttgttg caattgataa tctgaattta gatatacatg aaggggaatt
    13141 ctttacattt cttgggcctt caggatgtgg taaatcaact actttgagag cattggtagg
    13201 ttttttagat ccatcatcag gaagtattga agttaatgga acagatgtca ctcatttgga
    13261 acctgaaaag cgtggaattg gtattgtatt tcaatcttat gcgctatttc caactatgac
    13321 tgtttttgat aatattgcat ttggtttaaa agttaagaag gtagctccag atgttattaa
    13381 agctaaagta tcagcagtgg cagcaaaaat taagatctct gatcaacagt tacagcgtaa
    13441 tgtatcagaa ttatctgggg gtcaacaaca aagggtagca ttggctcgtg ctctggttct
    13501 tgaacctaaa attctttgtc tagatgaacc attgtcaaac cttgacgcaa aattacgtgt
    13561 agatttgaga aaagagttga aaagacttca aaaagagtta ggtattacta ctttatatgt
    13621 tactcatgat caagaggaag ccttgacttt atctgataga attgcagtct ttaacaatgg
    13681 atacatcgaa caggtcggta caccagtaga gatttatcat aattctcaaa ctgaatttgt
    13741 atgtgatttt attggagata ttaatgtttt gaccgatgaa acagtccacg aagtattatt
    13801 gaaaaataca agcgttttct tagaggataa aaaaggatac attcgattag agaaagttcg
    13861 attcaatcgt gaaactgaac aagattttat tctaaaaggg acaattattg atgttgagtt
    13921 ttctggagtt acaattcact atacaataaa agtttctgaa agtcagattc ttaatgtaac
    13981 aagtattgat agtcaggctg ctattagatc tgtcggagaa agtgtggaat tatttatcac
    14041 accatcagac gttctgcaat tttaaggagg tgcagtatgc gtcataaatt aaatttaaaa
    14101 gattggctta ttcgtttagg gttaatctgg ttcttagtaa catttattat ttatccaaac
    14161 tttgatctag tagtgaatgt atttgtaaaa ggaggagaat tttcccttga tgctgtacat
    14221 cgtgttctaa aatctcagag ggcacttcag agtattatga acagttttaa gttagcattt
    14281 tcactcatta ttacagttaa tgtcgtaggt attctttgtg ttctatttac agagtacttt
    14341 gatattaaag gtgctaaaat tttaaaatta ggttatatga cctctttaat ttatggagga
    14401 gtggttttag cgactggata taaatttgtc tatggtcctt atggattgat tacaaaattt
    14461 ttacaaaatg ttatcccttc tttagactct aactggttta ttgggtatgg tgcagtctta
    14521 ttcattatga cattttcagg aactgctaat catacattgt ttttaacaaa tacaattcga
    14581 agcgttgact atcacactat tgaggctgct cgaaatatgg gagcaaaacc atttactgtt
    14641 ttccgaaaag tagtgttacc aaccttaatt ccaactctat ttgcacttac tattatggtt
    14701 tttcttagtg gtttatctgc agtagcagca cccatgattg ttggtggtaa agaatttcaa
    14761 actataaatc caatgattat tacatttgca gggatgggga attctcgtga tttagctgcc
    14821 ttacttgcaa ttattttagg tattgcaact acaattttgc ttactatcat gaataagata
    14881 gaaaaaggtg gaaattatat ttctatctct aagactaaag cgcctcttaa aaaacaaaaa
    14941 attgcgtcta agccttggaa tatcattgct cacattgtag catatggatt gttcacagtt
    15001 ttcatgcttc cactaatttt tatagtatta tactcattta cagatccagt tgcaattcaa
    15061 acaggtaact taacattatc aaactttact ttagaaaatt atcgcttatt ctttagtaat
    15121 agtgcggcat tctctccatt cttggtcagc tttatttatt ctattattgc tgcgacaaca
    15181 gcaacaattc tcgcagttgt atttgctcgt gttgtcagaa aacataaatc tcgttttgat
    15241 ttcttatttg aatatggtgc tctacttcct tggttactac caagtacact tttagcagta
    15301 agtttattat ttacttttaa tcagccacaa tttcttgtct tgaatcagat tttggtaggt
    15361 agtttggtaa ttctacttat tgcatatata gttgtaaaaa tcccattttc ttatagaatg
    15421 gtacgtgcta ttttatttag tgttgatgat gagatggaag atgcagcaag aagtatgggt
    15481 gcttcacctt tttatactat gatgaaggtt atcattccat ttattttacc ggttgttctc
    15541 tctgttattg ctttaaactt taactcttta ttaactgact tcgacttatc tgtattcctt
    15601 taccatcccc tagctcaacc attaggtatt acgattcgat ctgcaggtga tgaaacagca
    15661 acatctaatg cacaagctct ggtatttgtt tatacaattg ttctgatgat tatttctgga
    15721 acggtattat acttcacaca aagaccgggg cgtaaagtaa ggaaataatc atgacagcca
    15781 ctagtcttgg gttatcaaat attgaaatag ttgtcaggat tgttttatca gtagtcattg
    15841 gtagtataat tggtttagag agagggagca aatcccagcc tgcaggcatc cgtacttata
    15901 gtattgtttg tctagctgca tgtttgatta tgatgacgaa tgaatacgta tcttataaat
    15961 ttgggacagg agatcctaca cgattaggag ctcaagttat atcaggtgtg ggttttctag
    16021 gcgctggaac gattcttatt acagataaaa agaaaattac aggtctgaca actgcagcag
    16081 gcatttgggc ttcggcagga attggattag ctattggagt aggtttttat gagggagctc
    16141 ttttagtagc tatttctgtt tggggtgtga tatccatgtt ccaaccacta aaaaaatatc
    16201 tgcaaaatcg ttctaaaatg attgaattgt atatagtggt taaatctaca gaagcctata
    16261 atcgtgtatt ggtttattgt gcagaaaatg gtatcagaat gaccgattca agaacagcgt
    16321 ttggagatgt taattctgac agaattgaat actttgatgt tccggacaaa aaaatagcgt
    16381 catttattac tctggaatta tcaggtagat ttgaacatct tcgactgatg gaagaaattg
    16441 ctaatattgt aggtgttatt tatgtcgaag aaattagctg aaatttagta aacaaaggga
    16501 cagatgtttt tgtccttttg ttttttagat gttttaatca tctaattttt gagtagattt
    16561 ttgctcagag gcttttatga aagattataa aatcaatttt gatttaggta aaatagaata
    16621 ttttgataat aattgtttga tacaagtata caaatttatt tctttttatg atatttgtga
    16681 aatggtgttt gcctttcatt tacctcctga tgagttgata acaaatgtta tctttaaaga
    16741 aaaaaataac tctatattaa aatgttaaat tgacaggcta ttatatgttt ttataaatcc
    16801 tacacatttt actgaaaaag ttaatctaca attttatgat agttttttct catatgaatt
    16861 tatttgtcgt gaagttggaa acattcttaa aaataaaggt gtgaaatgca atttaaactt
    16921 ttttgaaggg aaagaatatt tgtaaaatta attttgtgaa tttgtggatc ttaaataatt
    16981 tactaaattc tcttgttaaa aaaaattaaa tattgtatag taatattaga atgttcgtaa
    17041 tggaggactg aaatgaaaaa tataaatggg aaaaaggtaa ctatttatga tattgcacgt
    17101 ttatcaggtt tttctccaaa aacagtttca cgagttatta atggtggagt aaatgttaaa
    17161 gaagaaactt atcaagcgat tcaaaaagtt atagaggaat tgtcgtatat tccaaatgcg
    17221 tatgcaaaaa atttaactaa aaaagaagct ataaatatat tgatttctgt aaaaaaaatc
    17281 gactcttttc ctttaatttg gtttcatacg ctgttagata aagtgttacg gacgtgtaaa
    17341 gaatttggtg ttaatgctat agttgagtac tttggagagg aggatacaat tagtaattca
    17401 attatatcaa gcacaggtag cctagtagat ggtgttattg ttttttatga aagtgtagat
    17461 gatatcagaa ttcagtattt aaagaagaac catatgcctt ttcttgtttt cggtgaatct
    17521 caaacgtctg gagtagtcta tgtatctaat aataattttc aagctactta tgatatgatg
    17581 aaagctgtaa ctgaagaaaa atttaaaaat atgtggttgc ttatgggagg agaatcccat
    17641 gttaataagg atcgtgaaag aggtgtgcgt tcttttctga atgataaaaa ttactttatg
    17701 gatttaaaag tcatttatgg cttatctaca attgattcag tttattctta tgcaatgcag
    17761 cacttgacta cccaaaatta tccggacatt atttttgttt caggagatga aaaggttcag
    17821 ggcttgattc gtgcgtgcta tgagaaagga attcttattc cagatgatat ttctatcatt
    17881 ggatttgata atattcctat ttctcagtat tatactccag ctttgtctac aattgctccc
    17941 aattatgtta aattggctaa agaaatgata gaaggtgttt tagcaattat taaaggggaa
    18001 agtgtcacat ctgttgaagt ttctcctaaa tttgttagga gacagagttt ctagtattgt
    18061 ttaattcttg aaaatcctag tggaaaagat ggagtgttct aaaataagtt ctgtttagcc
    18121 tccattcagt ttctattgag ttggatccaa tttctaacaa gtgggacatg ttcatgttcg
    18181 atctaaggaa gacatggtca cattcgaatg atattttcaa aaaaatcgta aaaaagtctt
    18241 gacaaagaaa aaacaaagta ttaaaataag ttcaacaaat cagaaaagta actatttttg
    18301 atcttcaggg agcctgtggt gattgtgaat aggtggttgg aagtagtgaa agtgggctga
    18361 ttttgaaaat gaatttgaaa caatgaaaat tcggtgcgca caccttacag tgcagcttgt
    18421 tgttaaacaa ggcagagatg taaagggata gtccctttat aattgaggtg gcaccgcgtt
    18481 accaacgccc tcacacggaa gtatattctg tgtgtgggct tttttctatc cgtcgtttgg
    18541 tttatctttt attagggcct taagtcgctt tgatgaactt gagttctatc tacagctcct
    18601 tgcctactac taaaagcaaa caaaaaggct ggactaatac gaaaaaagct agtaatactc
    18661 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaaac actgttttga
    18721 ggttgtggat agaactgacg aagtcagctc aaaatactgt tttgaggttg t
//
LOCUS       DAVDHZ010000042        18415 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000042 DAVDHZ010000000
VERSION     DAVDHZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.043"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            1156..2415
                     /locus_tag="VUR46_001739"
     CDS             1156..2415
                     /locus_tag="VUR46_001739"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET5457116.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2431..2982
                     /locus_tag="VUR46_001740"
     CDS             2431..2982
                     /locus_tag="VUR46_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457117.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICNQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2975..4252
                     /locus_tag="VUR46_001741"
     CDS             2975..4252
                     /locus_tag="VUR46_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5457118.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4268..5128
                     /locus_tag="VUR46_001742"
     CDS             4268..5128
                     /locus_tag="VUR46_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET5457119.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNISKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5353..5463
                     /locus_tag="VUR46_001743"
                     /pseudo
     CDS             5353..5463
                     /locus_tag="VUR46_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            5509..6313
                     /locus_tag="VUR46_001744"
                     /pseudo
     CDS             5509..6313
                     /locus_tag="VUR46_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            6505..8796
                     /gene="pcrA"
                     /locus_tag="VUR46_001745"
     CDS             6505..8796
                     /gene="pcrA"
                     /locus_tag="VUR46_001745"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET5457120.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNIWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFFHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANMQDMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8839..9519
                     /gene="radC"
                     /locus_tag="VUR46_001746"
     CDS             8839..9519
                     /gene="radC"
                     /locus_tag="VUR46_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET5457121.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9516..10205)
                     /locus_tag="VUR46_001747"
     CDS             complement(9516..10205)
                     /locus_tag="VUR46_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET5457122.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGGQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDNVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(10223..10864)
                     /locus_tag="VUR46_001748"
     CDS             complement(10223..10864)
                     /locus_tag="VUR46_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET5457123.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10947..11153)
                     /locus_tag="VUR46_001749"
     CDS             complement(10947..11153)
                     /locus_tag="VUR46_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET5457124.1"
                     /translation="MFELTYKDCYHVERTLKYEALMLTLSGCVTLPDTLYVTSLTFRG
                     QKVYQGLVEDLYRFLSHADFLHQN"
     gene            complement(11161..11508)
                     /locus_tag="VUR46_001750"
     CDS             complement(11161..11508)
                     /locus_tag="VUR46_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET5457125.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11513..12628)
                     /locus_tag="VUR46_001751"
     CDS             complement(11513..12628)
                     /locus_tag="VUR46_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5457126.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQENHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGIVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12638..13597)
                     /locus_tag="VUR46_001752"
     CDS             complement(12638..13597)
                     /locus_tag="VUR46_001752"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET5457127.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13710..14279)
                     /locus_tag="VUR46_001753"
     CDS             complement(13710..14279)
                     /locus_tag="VUR46_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET5457128.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14407..15078
                     /locus_tag="VUR46_001754"
     CDS             14407..15078
                     /locus_tag="VUR46_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET5457129.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            15062..15880
                     /locus_tag="VUR46_001755"
     CDS             15062..15880
                     /locus_tag="VUR46_001755"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET5457130.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINCVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15877..16773
                     /locus_tag="VUR46_001756"
     CDS             15877..16773
                     /locus_tag="VUR46_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5457131.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16817..17791
                     /gene="pta"
                     /locus_tag="VUR46_001757"
     CDS             16817..17791
                     /gene="pta"
                     /locus_tag="VUR46_001757"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET5457132.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(18106..>18415)
                     /locus_tag="VUR46_001758"
     CDS             complement(18106..>18415)
                     /locus_tag="VUR46_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5457133.1"
                     /translation="QLLLFHFQNKEPEKFFGFIEDNLKQVHPIFQTVFKTFLKDKEKI
                     INALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA
                     "
BASE COUNT         5480 a         3343 c         4017 g         5575 t
ORIGIN      
        1 atttacccac tacaaatatt atagagccaa aaatcccgtg cctcatcaga cacgggattt
       61 tgtggtacga cgggcatgta tagcgaactg aatctggaat agcacagcat atcttctaaa
      121 atatagtaaa atgaaatgag aacaggacaa atcgatttct aacaatgttt tagaagtaga
      181 ggtgtactat tctagtttca atcaactata ttgttataaa ttgatttgaa tttcaaaatt
      241 aaattgtttg attcttattt caatttgtta tagtatatct gatgtcaaag ttctcggcga
      301 gtcaaatagc gattcccaag cctgactatc gtgaggtagc ggattaaaat ggtctgggga
      361 tagaccgttt taagtctgac gctggaaata agaattgtca gaagaaggga tagagaaatc
      421 gtggctctac gaacaggaac gtgataataa ggcgtatata gcggataaga gggcctcaaa
      481 ctctaaagtc caaaaaggta gtcgtaacct atatgcgtaa atcacgagag taattgaatt
      541 cgtactaaga ttttctattt tcactgtaac cttttaacgt ccttatatct tgtatacacg
      601 aggaaagatg tacgacttat cccgtgaggt ctatcactat aaagagaaaa cgacagatag
      661 aagtgatcct gagtcacggt tatctttaaa atagattgtc tgataggacg gtatgtataa
      721 aacgcttctg tgaactgaga gaaggggaga agttcttgct aaaatttagt tgaacagccg
      781 tattccgata cttagataag agatctagtc ttagccccta ctcagtttta ggggataaaa
      841 aaggggcaat agcgattcga gaaagattat actcttcgaa aatctcttca aatcacgtca
      901 atatcgcctt gccgtatgtg taggatactg actacgtcag ttccatctac aacctcaaaa
      961 cagtgttttg agcaacctgc ggttagtttc ctagtttgat ctttgatttt cattgagtat
     1021 tagtaattca gttactaact cgtcaactct gatttatcca ataaaattga aaaggatgga
     1081 aaaaaggata aatttatgat atactttatt ttgaagacct tattagaaat cttgaaagag
     1141 tattgaaaac ttagaatgag aaaaattgtt atcaatggtg gattaccact gcaaggtgaa
     1201 atcactatta gtggtgctaa aaatagtgtc gttgccttaa ttccagctat tatcttggct
     1261 gatgatgtgg tgactttgga ttgcgttcca gatatttcgg atgtagccag tcttgtcgaa
     1321 atcatggaat tgatgggagc tactgttaag cgttatgacg atgtattgga gattgaccca
     1381 agaggtgttc aaaatattcc aatgccttat ggtaaaatta acagtcttcg tgcatcttac
     1441 tatttttatg ggagcctctt aggccgtttt ggtgaagcga cagttggtct accgggagga
     1501 tgtgatcttg gtcctcgtcc gattgactta caccttaagg cgtttgaagc tatgggtgcc
     1561 actgctagct acgagggaga taacatgaag ttatctgcta aagatacagg acttcatggt
     1621 gcaagtattt acatggatac ggttagtgtg ggagcaacga ttaatacgat gattgctgcg
     1681 gttaaagcaa atggtcgtac tattattgaa aatgcagccc gtgaacctga gattattgat
     1741 gtagctactc tcttgaataa tatgggtgcc catatccgtg gggcaggaac taatatcatc
     1801 attattgatg gtgttgaaag attacatggg acacgtcatc aggtgattcc agaccgcatt
     1861 gaagctggaa catatatatc tttagctgct gcagttggta aaggaattcg tataaataat
     1921 gttctttacg aacacctgga agggtttatt gctaagttgg aagaaatggg agtgagaatg
     1981 actgtatctg aagacagcat ttttgtcgag gaacagtcta atttgaaagc aatcaatatt
     2041 aagacagctc cttacccagg ctttgcaact gatttgcaac aaccgcttac ccctctttta
     2101 ctaagagcga atggtcgtgg tacaattgtc gatacgattt acgaaaaacg tgtaaatcat
     2161 gtttttgaac tagcaaagat ggatgcggat atttcgacaa caaatggtca tattttgtac
     2221 acgggtggac gtgatttacg tggggccagt gttaaagcga ccgacttaag agctggggct
     2281 gcactagtca ttgctgggct tatggctgaa ggtaaaactg aaattaccaa tatcgagttt
     2341 atcttacgtg gttattctga tattatcgaa aaattacgta atttaggagc ggatattaga
     2401 cttgttgagg attaaaccgt agaggtgttt atgaatattt ggaccaaatt agcaatgttt
     2461 tctttttttg aaacggatcg cttgtatttg cgtcctttct tttttagtga tagtcaggac
     2521 ttccgcgaga tagcttcaaa tccagaaaat cttcaattta ttttcccaac gcaggcaagt
     2581 ctggaagaaa gtcaatatgc actggccaat tactttatga agtccccttt gggagtgtgg
     2641 gcaatttgta accagaaaaa tcaacaaatg attggttcta ttaaatttga gaagttagat
     2701 gaaatcaaaa aagaagctga gcttggctat tttttgagaa aagatgcttg gtcgcaagga
     2761 tttatgacag aggttgttag aaaaatttgt cagctttctt ttgaggaatt tggcttaaaa
     2821 caattatcta tcattaccca ccttgaaaat gaagctagcc aaagagttgc tcttaagtct
     2881 ggatttagtt tgttccgtca gtttaaggga agtgatcgtt acacaagaaa aatgcgggat
     2941 tatcttgaat ttcggtatgt aaaaggagag ttcaatgagt aagcatcagg aaattctaag
     3001 ctatttggag gaattaccag taggtaaaag ggtcagtgtt cgtagcattt cgaatcatct
     3061 aggagttagt gatggaacag cctatcgggc tattaaagaa gctgaaaacc gtggaattgt
     3121 ggagacccgt cctagaagtg gaacaattcg tgttaaatcc cagaaagttg ctatagagag
     3181 attaacgttt gctgaaattg cagaagtgac ttcttctgag gttctggctg ggcaagaagg
     3241 tttagagaga gaatttagta agttttcaat tggtgccatg actgaacaaa atatcttgtc
     3301 ttaccttcat gatggggggc tcttgattgt cggagaccga acccgtattc agttgctagc
     3361 cttggaaaat gaaaatgcag ttctggttac agggggattt caggttcatg atgatgtgct
     3421 taaactggcc aatcaaaaag ggattcctgt tctaagaagt aagcatgata cctttaccgt
     3481 cgcgaccatg atcaataaag ccttgtcaaa tgtccaaatc aagactgata ttctgacagt
     3541 tgagaaactt tatcgcccta gtcatgagta tggttttctg agagagacag atacagttaa
     3601 agattatttg gacttggttc gtaagaatcg tagcagccgt ttccctgtta tcaatcaaca
     3661 tcaggtcgtt gttggcgttg taaccatgag agacgctggt gataaatcac caagcacgac
     3721 aattgataag gttatgtctc gtagtctatt tttggttgga ttatcgacaa atattgccaa
     3781 tgtgagtcaa cggatgatcg cagaagactt tgaaatggta ccagttgttc gaagcaatca
     3841 aactttgctt ggcgttgtga cgcggcgaga tgtcatggag aagatgagtc gttcccaagt
     3901 ttcggctcta ccaacttttt ctgagcagat tggacaaaag ctctcttatc accatgatga
     3961 agtagtcatt acagtggaac cctttatgct agaaaaaaat ggagttttgg ctaatggtgt
     4021 attggcagaa attctgaccc acatgaccca agatttagtt gttaatagtg gtcgcaatct
     4081 cattatcgag cagatgctga tctacttttt gcaggctgtt cagatagatg atatattgcg
     4141 cattcaggca cggattattc atcatacgag acggtcagct ataattgatt acgatattta
     4201 tcatggtcac cagattgttt caaaagcaaa tgtgactgtt aaaattaatt agaaactagg
     4261 agaaaagatg ataacattaa aatcagctcg tgaaatcgaa gctatggaca aggctggtga
     4321 ttttctagca agtattcata taggcttacg tgatttgatt aagccaggcg tagatatgtg
     4381 ggaagttgaa gaatatgtcc gccgtcgttg taaagaagaa aatttccttc cacttcagat
     4441 tggggttgac ggtgccatga tggactatcc ttatgctacc tgttgctctc ttaacgatga
     4501 agtggctcac gctttccctc gtcattatat cttgaaagat ggtgatttgc tcaaagttga
     4561 tatggttttg ggaggtccca ttgctaaatc tgacctgaat atctcaaaat taaacttcaa
     4621 caatgttgaa caaatgaaaa aatatactca gagctattct ggtggtttag cagactcatg
     4681 ttgggcttat gctgttggta caccgtccga agaagtcaaa aatttgatgg atgtaaccaa
     4741 agaagctatg tacaagggta ttgagcaagc tgttgttgga aatcgtatcg gtgatatcgg
     4801 tgcggctatt caagaatacg ctgaaagtcg tggttacggt gtagtgcgtg atttggttgg
     4861 tcatggtgtt ggcccaacta tgcacgaaga accaatggtt cctaactatg gtattgcagg
     4921 tcgtggactc cgtcttcgtg aaggaatggt cttaaccatt gaaccaatga tcaatacagg
     4981 cgattgggaa attgatacag atatgaaaac tggttgggcg cataagacca ttgacggtgg
     5041 attgtcatgt cagtatgaac accaatttgt cattacgaaa gatggacctg ttatcttgac
     5101 tagccaaggt gaagaaggaa cttattaata aaaagtgaaa agactactgg aagtttattt
     5161 tgataaaaaa tccagtagat cttttcataa taaaacgcat tgtatcaagt gttaggggct
     5221 gatatcatgc gtttttctgc ttttaagatt ttttccaact ctgtttgtaa gcgcatcata
     5281 acaaagggtc taggattcag ggctctcctc ctatatacta ttagtaaagt aaaactaagg
     5341 gaggatattt tagtgtcgca gtctattgtt cctgtagaga ttccacaata ttgtcgtttt
     5401 gattctaaaa agagaaatgg aattctgttt aatgttcgta ttgccaatct taaatttacc
     5461 ttttttagat tagacttcct gcgaaacaaa atatggtata gtagttctat gaattatgaa
     5521 gcaagtaaac aactaactga tgcacgattt aaatgtcttg ttggtgttca gcgcacgact
     5581 tttgaagaga tgttagctgt attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga
     5641 cgaaaaccta aattaagcct agaagacttt cttatggcca ctcttcaata tgtgcgagaa
     5701 taccgcactt atgaacaaat tgcggctgat tttggtattc acgaaagcaa cttaatccgt
     5761 cggagctaat gggttgaagt aactcttgtt caaagtggtg ttacgatttc aagaactcct
     5821 ctcagttctg aggatacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa
     5881 aaaagaatta gcgaatgatt ctggtaaaaa gaaatgccac gctatgaagg ctcaagcgat
     5941 tgtcacaagt caagggagaa ttgtttcttt ggatatcgct gtgaactatt gtcatgatat
     6001 gaagttgttc aaaatgagtc gcagaaatat cggataagct ggaaaaatct tggctgacag
     6061 tggttatcaa gggcccatga agatatatcc tcaagcacaa actccacgta aatccagcaa
     6121 actcaagccg ctaacagttg aagataaagc ttataaccat gcgctatcca aggagagaag
     6181 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacttatcg
     6241 aaatcatcgt aaacgcttcg gattacaaat gaatttgatt gctggtatta tcaatcatga
     6301 actaggattc tagttttgca ggaagtctat tgaggtattg agctagttta tgaaaaaatt
     6361 gggtgaaaaa gtcgagtgtt ttagaaaccc acagtgtagt attctagttt caatccacta
     6421 tattttgcta ctccccgtaa agtttctatt ttccctgatt tctgatataa tagaaatatt
     6481 gacttcaaga gtaaggaaga gaagatgaac gcattattaa atggaatgaa tgaccgtcag
     6541 gctgaggcgg tgcaaacgac agaaggtccc ttgctaatca tggcaggggc tggttctgga
     6601 aagactcgtg ttttaaccca ccgtatcgct tatttgattg atgaaaagct ggtcaatcct
     6661 tggaatatct tggccattac ctttaccaac aaggctgcgc gtgagatgaa agagcgtgct
     6721 tatagcctca atccagcgac tcaggactgt ctgattgcga ccttccactc catgtgtgtg
     6781 cgtattttgc gtcgcgatgc ggaccatatt ggctacaatc gtaattttac aattgtggat
     6841 cctggtgaac agcgaacgct catgaaacgt attctcaaac agttgaactt ggatcctaaa
     6901 aaatggaatg aacgaactat tttggggacc atttccaatg ctaagaatga tttgattgat
     6961 gatgttgctt atgctgccca agctggcgat atgtatacgc aaattgtggc ccagtgttat
     7021 acagcctatc aaaaagaact tcgtcagtct gaatccgttg actttgatga tttgattatg
     7081 ctgaccttgc gtctctttga tcaaaatcct gatgttttga cctactacca gcaaaaattc
     7141 caatacatcc acgttgatga gtaccaagat accaaccacg ctcagtacca attggtcaaa
     7201 ctcttggctt cccgttttaa aaatatctgt gtggttgggg atgcagacca gtctatctac
     7261 ggttggcgtg gtgctgatat gcagaatatc ttggactttg aaaaggatta ccccaaagcc
     7321 aaggttgttt tgttggagga aaattaccgc tcaaccaaaa ccattctcca agcggccaac
     7381 gaggttatta aaaacaataa aaatcgccgt cctaaaaata tctggactca aaacgctgat
     7441 ggggagcaaa tcgtttacta tcgtgccgat gatgagctgg atgaggctgt atttgtagcc
     7501 agaaccatcg atgaacttag tcgcagtcaa aacttctttc ataaggattt tgcagttctc
     7561 tatcggacta atgcccagtc ccgtacaatt gaggaagccc tgctcaagtc taacattcct
     7621 tataccatgg ttggcggaac caaattctac agccgtaagg aaattcgcga tattattgct
     7681 tatctcaacc ttattgctaa tttgagtgac aatattagtt ttgagcgtat tatcaacgag
     7741 cctaaacgag gaattggtcc aggtacagtt gagaaaatcc gtgattttgc gaatatgcaa
     7801 gacatgtcca tgctagatgc ttctgctaat attatgttgt ctggtatcaa gggtaaggca
     7861 gcccaatcta tctgggattt tgccaatatg atgcttgatt tgcgggagca gctagaccac
     7921 ttaagcatta cagagttggt tgagtccgtc ctagaaaaaa caggttatgt cgatattctt
     7981 aacgcccaag cgactctaga aagcaaggca cgggttgaaa atatcgaaga gtttctttct
     8041 gttacgaaga actttgatga caccactgat gtgacagaag aggaaactgg tctggacaaa
     8101 ctgagtcgtt tcttaaatga cttggctttg attgccgaca cagattcagg tagtcaggag
     8161 acatcagaag tgaccttgat gaccctgcat gctgccaaag gtctcgaatt tccagttgtc
     8221 tttttgattg ggatggaaga aaatgtcttt ccacttagtc gtgcgactga agatccagat
     8281 gaattagaag aagagcgccg tctagcctat gtaggtatca cgcgtgcaga gaaaattctc
     8341 tatctgacca atgccaactc acgcttgctt tttggtcgta ccaattataa ccgtccgact
     8401 cgttttatta acgaaatcag ttcagacttg cttgagtatc aaggtctggc tcgtcctgca
     8461 aatacaagct ttaaggcatc atatagcagt ggtagtattt cctttggtca aggtatgagt
     8521 ttggctcagg ctcttcaaga ccgtaaacgc ggtgctgccc caaaatcaat ccagtcaagc
     8581 ggtcttccat ttggtcaatt tacagctggc gcaaaaccag catctagcga ggcaaattgg
     8641 tccattggtg atattgctct ccacaagaaa tggggagagg gaaccgttct ggaagtttca
     8701 ggtagcggtg ctaggcagga attgaaaatc aatttcccag aagtaggttt gaaaaaactt
     8761 ttagccagtg tggctccaat tgagaaaaaa atctaatttt ccatccttct cacgaataat
     8821 aaagtgagga ggatttttat gtacagtatt tcattccaag aagattcact attaccaaga
     8881 gaaaggctgg ccaaggaagg agttgaagcg cttagtaacc aagagttgct agctatttta
     8941 ctcaggacag gaacacgtca agttagcgtt tttgaaattg cccaaaaagt cttgaacaat
     9001 ctttcaagcc taacggattt gaaaaaaatg accctgcagg aattgcagag tttgtctggt
     9061 attgggcgtg ttaaggccat agaattacaa gctatgattg aactggggca tcgtattcac
     9121 aaacacgaga ctcttgaaat ggaaagtatt ctcagcagtc aaaagttggc caagaagatg
     9181 cagcaggaat taggggataa aaaacaagag cacctggtgg cactctatct caatactcaa
     9241 aatcaaatca tccatcagca gaccattttt atcggttctg taactcgtag tatcgctgaa
     9301 ccgcgagaga ttcttcacta tgcaatcaag catatggcga cttctcttat cttggtccac
     9361 aatcatcctt caggagcggt agcgcctagc caaaatgatg atcatgtcac taaacttgtt
     9421 aaagaagcct gcgaactgat ggggattgtt ctcttggacc atttgattgt ctctcattct
     9481 aattacttta gttatcgtga aaagacagat ttaatctaaa gttcattaac gacatagtca
     9541 aagagtttct tatctttggg acgattttca aaaagaagtt ctggatgcca ttggacaccg
     9601 agaaaggcga cattatccgt actcatgaca gcctcaatga taccatcttt aggatcatga
     9661 gccacaactt ttaaatttgg tgctaagtcc ttgatgctct ggtggtggaa ggagttgata
     9721 tgagagattt ctccatagat ttcttggaga acggtatctg gttctgttac caagcgttga
     9781 gttgtgtact caacagaaga atcctgccaa tggtcttcga tatcttggta caaagttcca
     9841 cccatggcaa cgttaaagag ttgggtacca cggcagacag agaaaatggg ctttttctgt
     9901 ttaatagctt ccttgatgag ggccagttcg aagatatctc tttgaaggtg atagtcatcg
     9961 ctatcaatgg ttttgggttc gccatagaat tttggatcga cattttgccc acctgtcaag
    10021 atgagcttgt caatcaaact gatatagtgg caggccattt cttgaccacc aatcggtagg
    10081 atgatgggaa tccctccagc atctttaacg ccttcaacaa agccttttgc tgcgtagctc
    10141 atcatgatgt catcatctgg atgagctttt tcgtttcctg taatcccaat aactggtttt
    10201 ttcataaaat gattttcgct ttctaatcct cttttcgcat gaagtagagg agggtttgga
    10261 gttcacttgt caaatcgaca tactgaacga ccacgtcttt tggtaaatgc agatggactg
    10321 gtgaaaaact gagaattcct ttcacaccag catcaaccaa gagattagca acttcttgtg
    10381 acttgacgct gggaacagtt aggatagcag tcttcacatc agcatccttg attttatcct
    10441 tgatctgaga aatcccgtaa atgggaatcc cgtcaggagt ttgggtaccg acttcaggat
    10501 ggtcatctag gtcaaaggcc atgataatct tcatcttgtt acgttcgtgg aagcggtagt
    10561 ggagaagggc atggcccata tttccaatac caaccagcat gacattggtg atggagttat
    10621 cattgagcaa atcggcaaaa aatgtcatta gttttttgac atcatagcca aaaccacgcc
    10681 gaccaagttc accaaaatag gaaaaatcac gacgtacggt cgctgaatca atcccaatgg
    10741 cctctgcaat ttgcttagag ttggcacgtt caatcttttc tgcatgaaat ctcttaaaaa
    10801 ttcgatagta gagagagagt ctttttgctg tagcttttgg aatagcaaac tgtttatctt
    10861 tcacaaaatc acaacctttc tattcttcta ttttatagaa atattgtgaa aaaatcaaca
    10921 aaaataagaa aaaactaaga aaaatcttag ttttgatgta aaaaatctgc atgagataga
    10981 aaacggtaga ggtcttcgac cagaccctga taaactttct gacccctaaa agtcagagaa
    11041 gtcacataaa gtgtatctgg taaggttaca catcctgaca aagtcaacat gagagcctca
    11101 tacttgagag tacgctctac atgatagcag tccttatagg tcagttcaaa cattttggct
    11161 ctatctttcc gattttgtaa agacaccacg ttctaccaag ctatccatga ggaagtagaa
    11221 tttttcctga tgaatgtggt ggtcttctga tttgaaaata tcaactagac gaaggccaaa
    11281 cttgtcagtg atattgattt tagcccctgt aagttccttg ttaatgatga ttttgagttg
    11341 gaagccttca ccgctgtttg gcactttttc caaaaggcga gtcagttcat agttaccaac
    11401 cttagtttca aaaaaggtgt tatctttgag ggtgaatttt ttaacagaag ggctaagagt
    11461 gtaatcgtaa cgacaatttt ttaactgaat gattttttca aatgccatat ggctaacctc
    11521 cgataatttc ttttaaggtt tttgcgaggg tttgtaggtc ttcaacggta ttttgtggcg
    11581 acaaactgat gcgaagggat tccttcaagc gttctgaatt tgcgccatac atggcttcaa
    11641 gaacatggct ggattggaca atgcctgcag tacaggctga gccagtagag attgaaattc
    11701 cagctaaatc tagccgaagg agtaagaggt catttttctg accaggaaat ccaatattga
    11761 gaacataagg gagatgatgt tttcctctat tcaagtaata ctgaattccc tccagctctg
    11821 ccagaaaggc agtttctaga ttttgtacat gttgaaaatg ttcttcttgt ttttctaggt
    11881 cttcttttag ggctgcaacc atgcctacaa tggcaggcag attttcagtt cctgcacgtt
    11941 ttttctgttc ctggtctccg ccatgtagat aggaatcaaa gtccatgcta gatgcgtaga
    12001 gaaaaccgat tcccttagga ccatggaatt tgtgggcaga agcagtgaga aaatcaatgc
    12061 ccaattcttc tgaatgaatt gggattttac caatagcctg aactgcatca acatgatagg
    12121 cagcagggtg ttgcttgagt atttggccaa tttcagcgat gggcagtagg tttcctgtct
    12181 cattattggc aaacatggtg gaaaccaaaa tcgtatcgtc acgtaaagcc ttttgaattt
    12241 gctgggctgt gatttcttga ttttctggct ggataatggt tgcttcaaac ccaaagtgtt
    12301 gaaccaagta atcaattgtt tcaaggacag catggtgctc gatggcagtt gtgatgatat
    12361 gttttccttg ttcttggtga cgaagacagt agccaatgat ggtagtatta ttgccttcag
    12421 tcccaccaga agtgaaaaag atatgttgag gttttgtcct tagtaactgg gctagttcct
    12481 gacgggcttc tcgcaagagt ttgccagctt gacgaccatg accatgaata ctagaaggat
    12541 ttccgtggtt ttcttgcata accttggtca tagctgaaat agcaactgct gacataggag
    12601 tcgttgcagc attgtccaaa taaatcaaag aatcacctta tttcttttta ttgtaggcaa
    12661 agagtgggct gactggtttt ctttcgtgaa tacggacgat agcatcacca attaactcac
    12721 tagcagtgat atagcataca tttttaggag ttttttcttt tgttgctact gaatcagtca
    12781 caagaatttc tttaatatta gtattgtcaa gaagctcagc agctccctcg acgaagagac
    12841 cgtggctaga aacagcataa atttctgtag ctccttcacg ttcaacgatt ttagaagctt
    12901 cagagaaggt acgtcctgta tttaaaatat catcaatcaa gatagctttc ttaccttcaa
    12961 catcaccaat aatataacct tcgttacgag ttgcatcgtc ttgagggtag tcgataatgg
    13021 cgataggagc atcaagatat tcagccaggc tacgcgcacg tttgacacct gaatttttag
    13081 ggctaacgac aacaacatct gaaccaagca atcctttatc gcagtaatgt tttgcgaata
    13141 ggggaacagt gaaaagatta tccactggaa tatcaaagaa accttgaacc tgaacggcat
    13201 gcaaatcaag agtcaggata cgatcaactc cagccttaac cagcatattg gcaactagtt
    13261 ttgctgtaag tggctcacga ggacaagcaa tgcggtcttg acgtgcatag ccaaaatatg
    13321 gaaggacaac gttgatactg tgggcacttg cacgcacaca agcatcgacc atgattaaca
    13381 attccattag gtggttgttg acagggaaac ttgttgattg gatgatgtaa acatcataac
    13441 cacggacact ttcttcgata tttacttgga tttctccgtc tgaaaattga cgtgatgata
    13501 gttttccaag tgggacacca acagcttggg caattttttg tgcaatctct tggttagagt
    13561 tgagtgcgaa aagtttcatg ttttttctat ctgacattat agaccgtcct ctgtaaactt
    13621 tataaatcct agttatattt accttacata tatgaactgg gatttgtgta tttttatctt
    13681 ttctatttta ccaaaaaatg gagattattt cagctatttt tcatactttt gacaaatcga
    13741 accaattttg aaggagcttt ttggtaggaa atctgatttt tctctaaaaa ttgtcggaaa
    13801 tcctgtttgc cttgctcatg attttccact tcaagctcca attcgtaatc tgtcatatca
    13861 aagtatcggc tctgatccag tgccatgaga ccaatagctg ttttcatttc atagcgaagc
    13921 gttgttagac aaccaagaac ctgccagttc ttactttgga taccatgttt cgccaattca
    13981 tccagtacta gcccttgagg aagttcttcc ttactcagat agttctcagc atcttttagt
    14041 tgcaattttt ggttgtattc catgtttcca acactctgcg ggactttgag tgtcaactca
    14101 gcccagtctt caaaggttcg aatgcgcata gcgactttct tttctcgcag ttcaaaatca
    14161 ggcgtgtcta tgtagtaatt tgtttgaaga acaggagtga cacctgtgaa ctggtctttt
    14221 agacgattgt attcatcttt tttcaatagt gttttcaatt caatttctaa atgtttcatt
    14281 tttcttacct ttttttatcg ttgaaagcgg atttatggta taataagcat tgtatttatt
    14341 gtatatgaat ctggagaaaa aatcaaagat atttttgacg gataatatga gaacaaggga
    14401 gaatatatga ccttagaatg ggaagaattt ctagatcctt acattcaagc tgttggtgag
    14461 ttaaagatta aacttcgtgg tattcgtaag caatatcgta agcaaaataa gcattctcca
    14521 attgagtttg tgaccggtcg agttaagcca attgagagca tcaaagaaaa aatggctcgt
    14581 cgtggcatta cttatgcgac cttggaacac gatttgcagg atattgctgg cttacgtgtg
    14641 atggttcagt ttgtagatga cgtcaaggaa gtagtggata ttttgcacaa gcgtcaggat
    14701 atgcgaatca tacaggagcg agattacatt actcatagaa aagcatcagg ctatcgttcc
    14761 tatcatgtgg tagtagaata tacggttgat accatcaatg gagttaagac tattttggca
    14821 gaaattcaaa ttcgtacttt ggccatgaat ttctgggcaa cgatagaaca ttctctcaac
    14881 tacaagtacc aaggggattt cccagatgag attaagaagc gactggaaat tacagctaga
    14941 atcgcccatc agttggatga agaaatgggt gaaattcgtg atgatatcca agaagcccag
    15001 gcactttttg atcctttgag tagaaaatta aatgacggtg taggaaacag tgacgataca
    15061 gatgaagaat acaggtaaac gaattgatct gatagccaat agaaaaccgc agagtcaaag
    15121 ggttttgtat gaattgcgag atcgtttgaa gagaaatcag tttatactca atgataccaa
    15181 tccggatatt gtcatttcca ttggcgggga tggtatgctc ttgtcggcct ttcataagta
    15241 cgaaaatcag cttgacaagg tccgctttat cggtcttcat actggacatt tgggcttcta
    15301 tacagattat cgtgattttg agttggacaa gctagtgact aatttgcagc tagatactgg
    15361 ggcaagggtt tcttaccctg ttctgaatgt gaaggtcttt cttgaaaatg gtgaagttaa
    15421 gattttcaga gcactcaacg aagccagcat ccgcaggtct gatcgaacca tggtggcaga
    15481 tattgtaata aattgtgttc cctttgaacg ttttcgtgga gacgggctaa cagtttcgac
    15541 accgactggt agtactgcct ataacaagtc tcttggcggt gctgttttac accctaccat
    15601 tgaagctttg caattaacgg aaattgccag ccttaataat cgtgtttatc gaacactggg
    15661 ctcttccatt attgtgccta agaaggataa gattgaactt attccaacaa gaaatgatta
    15721 tcatactatt tcggttgaca atagcgttta ttctttccgt aatattgagc gtattgagta
    15781 tcaaatcgac catcataaga ttcactttgt cgcgactcct agccatacca gtttctggaa
    15841 ccgtgttaag gatgccttta tcggtgaggt ggatgaatga ggtttgaatt tatcgcagat
    15901 gaacatgtca aggttaagac ctttttaaaa aagcacgagg tttctaaggg attgctggcc
    15961 aagattaagt ttcgaggtgg agctattctg gtcaataatc aaccgcaaaa tgcaacgtat
    16021 ctattggacg ttggagacta cgttaccatt tacattcccg ctgaggaagg ctttgaaacc
    16081 ttggaggcta ttgagcatcc attagatatt ctctatgagg atgaccactt tctagtcttg
    16141 aataaaccct atggagtggc ttctattcct agtgtcaatc actctaatac cattgccaat
    16201 tttatcaagg gttactatgt caagcaaaat tatgaaaatc agcaggttca cattgttacc
    16261 agactagata gggacacttc tggcttgatg ctctttgcca agcacggtta tgcccatgca
    16321 cgattagaca agcagttgca gaagaaatct atcgagaaac gctactttgc tttggttaag
    16381 ggagatggac atttggagcc agaaggggaa attattgctc cgattgcgcg tgatgaagat
    16441 tccattatta ccagacgagt ggctaaaggc ggaaagtatg cccatacttc atacaagatt
    16501 gtagcttctt atggaaatat tcacttggtc tatattcacc tgcacactgg tcgaacccat
    16561 caaatccgag tccatttttc tcatatcggt tttcctttgc tgggagatga tttgtatggt
    16621 ggtagtctgg aagatggtat tcaacgtcag gctctgcatt gccattacct atccttttat
    16681 catccatttt tagagcaaga cttgcagtta gaaagtccct tgccggatga tttcagtaac
    16741 cttattaccc agttatcaac taatactcta taaaaactgt ctcagagtat aattattatc
    16801 ttaaaggaga aaactcatgg aagtttttga aagtctcaaa gccaaccttg ttggtaaaaa
    16861 tgctcgtatc gttctccctg aaggggaaga gcctcgtatt cttcaagcaa caaaacgctt
    16921 agtaaaagaa acagaagtga ttcctgtttt gcttggaaat cctgaaaaaa ttaaaattta
    16981 tcttgaaatt gaaggaatca tggatggtta tgaggtcatc gaccctcaac attatcctca
    17041 atttgaagaa atggtttctg ccttggtgga gcgtcgcaag ggcaaaatga ctgaagaaga
    17101 tgtacgcaag gttttggttg aagatgtcaa ctactttggt gtgatgttgg tttacttggg
    17161 cttggttgat ggaatggtgt caggagcgat tcactcaaca gcttcaacag ttcgcccagc
    17221 tctacaaatc atcaaaactc gtccaaatgt aactcgtact tcaggagcct tcctcatggt
    17281 tcgtggtacg gaacgttacc tatttggaga ctgtgccatt aacatcaatc cagatgcaga
    17341 agccttggct gaaattgcca tcaactcagc aatcacagct aagatgtttg gcatcgaacc
    17401 taaaattgcc atgttgagct attctactaa aggttcaggg tttggtgaaa gcgttgataa
    17461 ggtcgttgaa gcaactaaaa ttgctcacga cttgcgtcct gaccttgaaa tcgatggtga
    17521 gttgcaattt gatgcggcct ttgttcccga aactgcagct ctgaaagctc ctggaagtac
    17581 ggtagctggt caagcaaatg tcttcatctt cccaggtatc gaggcaggaa atattggtta
    17641 caagatggct gaacgtcttg gtggttttgc agctgtagga cctgttttgc aaggtttgaa
    17701 caaaccagtt aacgaccttt ctcgtggatg taatgcagat gatgtttaca agttaaccct
    17761 tatcacagca gctcaagcag ttcatcaata gtgaaaacta taaagcgata tactatgcta
    17821 tactgtagtt atgaaactat gtacgaaaag cactgccatt aattcctgag aactaaatta
    17881 ctgattggtg tcaaaaagga aaacttccaa gcgatgatat cctgtctata cacgacctat
    17941 agaaatctgt aatatacatg tccgtaaaac gataaattcc ctttttgatt ttaaatgagt
    18001 atgaaaagag aattttttca tgagaaaacg cataatattg agtgctttga cacctgctat
    18061 tatgcgtttt ctggctcttt gtcaactgta gtgggttgaa gtcagctaag ctcgagaaag
    18121 gacaaatttt gtcctttctt ttttgatatt cagagcgata aaaatccgtt ttttgaagtt
    18181 ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt ttgatgagat tattggtcgc
    18241 ttccagtttg gcattagaat agtgtagttg aagggcgttg ataatctttt ctttatcttt
    18301 gaggaaggtt ttaaagacag tctgaaaaat aggatgaacc tgcttaagat tgtcctcaat
    18361 gaatccgaaa aatttctccg gttccttatt ctggaagtga aaaagcaaga gctga
//
LOCUS       DAVDHZ010000043        18193 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000043 DAVDHZ010000000
VERSION     DAVDHZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.044"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            16..86
                     /locus_tag="VUR46_001759"
     tRNA            16..86
                     /locus_tag="VUR46_001759"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="VUR46_001760"
     tRNA            122..195
                     /locus_tag="VUR46_001760"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="VUR46_001761"
     tRNA            202..289
                     /locus_tag="VUR46_001761"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(415..1350)
                     /gene="birA"
                     /locus_tag="VUR46_001762"
     CDS             complement(415..1350)
                     /gene="birA"
                     /locus_tag="VUR46_001762"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HET5457134.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDIDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1347..2207)
                     /locus_tag="VUR46_001763"
     CDS             complement(1347..2207)
                     /locus_tag="VUR46_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET5457135.1"
                     /translation="MLVFSEYQTGTINLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2315..4477
                     /locus_tag="VUR46_001764"
     CDS             2315..4477
                     /locus_tag="VUR46_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET5457136.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVIDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVKKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADESKKVDIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNIDAIARLPIQYGSSYLYPTISMGD
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVSLSQGDFLSRQYIFRKL"
     gene            4569..5828
                     /locus_tag="VUR46_001765"
     CDS             4569..5828
                     /locus_tag="VUR46_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5457137.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGVGDLAWSISATTKHPKEANAFVEYMTRPE
                     VIQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5842..6708
                     /locus_tag="VUR46_001766"
     CDS             5842..6708
                     /locus_tag="VUR46_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5457138.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6722..7555
                     /locus_tag="VUR46_001767"
     CDS             6722..7555
                     /locus_tag="VUR46_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5457139.1"
                     /translation="MKQDGRKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNFVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7867..9309
                     /gene="gtfA"
                     /locus_tag="VUR46_001768"
     CDS             7867..9309
                     /gene="gtfA"
                     /locus_tag="VUR46_001768"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET5457140.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYVEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPIQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYYFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9447..10640
                     /locus_tag="VUR46_001769"
     CDS             9447..10640
                     /locus_tag="VUR46_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET5457141.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11327..13306
                     /locus_tag="VUR46_001770"
     CDS             11327..13306
                     /locus_tag="VUR46_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5457142.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13373..14869
                     /locus_tag="VUR46_001771"
     CDS             13373..14869
                     /locus_tag="VUR46_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5457143.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14869..15795
                     /locus_tag="VUR46_001772"
     CDS             14869..15795
                     /locus_tag="VUR46_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5457144.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15804..16871
                     /locus_tag="VUR46_001773"
     CDS             15804..16871
                     /locus_tag="VUR46_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457145.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKICEKMGFAHLAD"
     gene            16882..17808
                     /locus_tag="VUR46_001774"
     CDS             16882..17808
                     /locus_tag="VUR46_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457146.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(17883..>18193)
                     /locus_tag="VUR46_001775"
     CDS             complement(17883..>18193)
                     /locus_tag="VUR46_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5457147.1"
                     /translation="QLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKI
                     VNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFRKRIFIALNIKKERTKFVLSRA
                     "
BASE COUNT         5325 a         3229 c         3836 g         5803 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagaga caataaaact tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatat cgtttatatt ataattgtgt tattttactt
      421 ccaactattg agagaaattt cgccactatt tagccagatt tcttttccgt tatcacattg
      481 aactaaaagt tttccatttt ctgagatgtc tttagcaagt cccttgtagt ctttttgctc
      541 tagtgtgaaa gtgacttctt ttcctagaat gaatgactgt tttttgtata ggtataatag
      601 ctcttctgct ggtgtttcga agaaagtacg ccagatttct atgatcaatt cattccttgt
      661 tataggagct gtagctttaa ataagctggc agctttttct tttaattcct gagggaagtc
      721 tttaatagtg aaattgatac ctactccaat aatgatatct gtgactaagc cagtttctac
      781 agaggtcatt gcttcagtaa ggattcctcc aattttatga ttgtttagat agatatcatt
      841 gacccatttt atgtcgatat ctattaaagt taggttctta atggctttgt agacagctcc
      901 agctacaagt agtgtgtagg atggtaattt gtcatagggg agatttggtt taagatggag
      961 tgtcatataa ataccacctt gtggtgagta gaaggaacgt tgaaaacggc ctcggcctgc
     1021 tgtttgatag gaagctagat agagggtatt tgcttcatgg cctaaatcaa ttgcttcttt
     1081 tgcatctagt tgtgttgatt ttgtttcggg tttaaagctg actttaattg gaagattttc
     1141 ttctagaatc tctggaagaa taaggtcacc attcatcagt ttgtatcctc tatttttgat
     1201 actatcaatt tcaatgcctt cttgttctag tcgcttgatg gctttccaaa ttgatgttcg
     1261 gcttagggat agtttttctg cgattttttc tccgctgata tagtcggttt ctttagatag
     1321 gatttggtag acagcttggt aggatttcat aatgttgcct ttctcactag ttggtattga
     1381 gagtattctt ttcttgtatg acttggagtc tgattaaagt attgtttata agctttcgaa
     1441 aaatggagtg gatctgaaaa acctaccgag tatgcaatta ccttgatgga ctcttgggta
     1501 ttttcgagaa gttgtctagc tcggtgcatt cgaacgtaga gtaggtattc tttgggtgat
     1561 aaggtattaa attctttgaa tacgcttgat aagtagcttc tgtgaacgga tagttctttt
     1621 gctaaatctt gaattgtaag tgattgagga tagtggctat caattaatcg tttgcattca
     1681 agatagagtt ggtgggttga tgaaatattc ttttttttct gattgggagc aatagttccc
     1741 agatgaaaca tcagttcatg aagttgtccc atgatatgga gttgagctaa ttcacttgat
     1801 tttgtaatct gagcgaagcg gacaatgtct gagatgagtt ttgcagtagt ctgggtatga
     1861 caagtttcag attggatgag ataagattga tcagaaattt gagaaagagc aaaataatca
     1921 ggggctttcc ctccagtgat tcctaaccag tagtaggccc aaggttcttt actatctgct
     1981 tgataaaagg ttagttcctc tggttttaat agaaagaaat ctccttcttt taaatcaaca
     2041 attttaccct tgtaatgaaa ttttccttgt cctttagtaa tgtaatgtag gacgtatgta
     2101 tcacgaatgg ctggaccaaa agagtaatta ggtgtgcatt cctcatatcc ataaaagctt
     2161 agggcaaggt tgattgttcc agtctggtat tctgaaaaaa ctaacatgtg ctacctccta
     2221 cctaacattt taccatattc ttgagacatt tttctatttt ggaaagcgat ttcaggtgat
     2281 aaaatataat caataaagtg atgaggtgaa gtaaatggga gttaggatag agaataatct
     2341 attttatgtt gagagtaaaa atctaagttt gattattgaa aatcgaaatg gctacttact
     2401 tttgaaacat ttaggaaaga ctattaagaa ctataaaggt tccaatagtg tttatgaacg
     2461 agaccatgcc ttttcaggaa atccaacggc tactaatcga acctttagtt tagatactca
     2521 gcgacagatt tttggacaac atggcttagg agattttagg aaaccaacca tacaggttca
     2581 gcatagtgta actgaagtaa tagactttcg atttgtagaa gcaaagattt taaaaggtca
     2641 gaatggtcca cagggcttac cttctccaca tagcatggac gatacagaga ctcttgtctt
     2701 aatgttagaa gattctaagg ctcaacttag tctgactttg tattatacta cttttaataa
     2761 tgatgcgact attgctagct acagtaaatt agataataat agtaatcagg aagttgtcat
     2821 ccataaagat ttttctttta tggctgattt tccagctgca gattacgaaa tagtaactct
     2881 gcagggtgct tatgctcgtg aaaagactgt tagacgtcaa caggtagaac aaggaatctt
     2941 ttcgattagt tcaaaccgag gtgcttctgg tcatgctcaa acaccagctc ttctactatg
     3001 cgaacaagga gtcacagagg atgctgggaa tgtgtttgct attcaactaa tgtatagtgg
     3061 caactttgaa gcttttgtta aaaaaaatca attgaatgaa gttcgggtgg ctattggcat
     3121 taatccagaa aacttttctt ggaagttagc ccctgaggaa tactttgaaa caccggtagc
     3181 tttagtgact cattcagatc agggattaac tggtattagt catgaaagtc agaattttgt
     3241 actgaagcac attattctaa gtgaattttc taaaaaagaa cgtccaattc taatcaataa
     3301 ctgggaagct acttactttg actttcagag agaaaaactg ttagagttag cagatgaatc
     3361 taagaaagtt gacattgaac tttttgtatt agatgatggt tggtttggca atcgttttga
     3421 tgataatcgt gctttaggtg attgggttgt taatgaggaa aaactgggtg gaagtctaga
     3481 aagtctgatt tcagctatcc atgaaagagg tttgcagttt ggactttggt tagaacccga
     3541 aatgatttct gtagatagtg atttgtatcg tcaacatcct gactgggcta ttcaggttcc
     3601 tgattatgag catacttatt ctcggaatca attagtactt aatcttgcca atcctcaggt
     3661 agtagaatac ttgaaaagtg tcttagatca actcctatct tatcatgaga ttgattacat
     3721 taaatgggat atgaaccgca atatcactaa gctagggaat ggattaactt atctagagac
     3781 acagatgcaa tctcatcagt acatgctggg gctttacgaa ctcgtttctt atctgacaga
     3841 gaagcacagc catattctct ttgagtcctg ctctggtggt ggtggacgaa atgatcttgg
     3901 tatgatacgc tatttcccac aagtctgggc tagtgataat attgatgcca ttgcacgttt
     3961 accaattcaa tacggttcat cctatctcta tccaaccatt tctatggggg atcatgtgtc
     4021 agcagtaccg aatcatcaga tgggacgaat gacaccatta gaaacacgtg gccatgtagc
     4081 aatgatggga aatttgggct atgagcttga tttgacaaat ttatcagatg aagagaaagc
     4141 tacgattgct aatcaggtga acttgtataa agaattacga ccagtagttc agttaggaca
     4201 gcagtataga ctaattaatc ctgatactgc atccaatgaa gcagctgtac aatttaatta
     4261 cggaaatcaa acgattgtaa cctacgttcg cgttttatct gttgtagaga ccatggaaac
     4321 aactttaaaa ttaaaagatt tggatgaaga gggactatat aaattacagg aaaatggcga
     4381 agtttactca ggtgcagaac taatgtatgc gggcttaact gttagcttat cccaaggaga
     4441 ttttttgagt agacagtata tttttagaaa actatgatat gtactgaccc caaaagttag
     4501 attttttctg tctaactttt ggggtgcagt tcaataaggg tgtataaatt tataaaggag
     4561 gctttctaat ggaatggtat aaaaaaatcg gacttcttgc aactacaggt ttagctttgt
     4621 ttgggctcgg cgcttgctcc aactatggta aatctgcgga tggcacagtg accatcgagt
     4681 atttcaacca gaaaaaagaa atgaccaaaa ccttggaaga aatcactcgt gattttgaga
     4741 aggaaaaccc taagatcaag gtcaaagtcg tcaatgtacc aaatgctggt gaagtattga
     4801 agacacgcgt tctcgcagga gatgtgcctg atgtggtcaa tatttaccca cagtccatcg
     4861 aactgcaaga atgggcaaaa gcaggtgttt ttgaagattt gagcaacaaa gactacctga
     4921 aacgcgtgaa aaatggctac gctgaaaaat atgctgtaaa cgaaaaagtt tacaacgttc
     4981 cttttacagc taatgcttat ggaatttact acaacaaaga taaattcgaa gaactgggct
     5041 tgaaggttcc tgaaacctgg gatgaatttg aacagttagt caaagatatc gttgctaaag
     5101 gacaaacacc atttggaatt gcaggtgcag atgcttggac actcaatggt tacaatcaat
     5161 tagcctttgc gacagcaaca ggtggaggaa aagaagcaaa tcaatacctt cgttattctc
     5221 aaccaaatgc cattaaattg tcggatccga ttatgaaaga tgatatcaag gtcatggaca
     5281 tccttcgcat caatggctct aagcaaaaga actgggaagg tgctggctat accgatgtta
     5341 tcggagcctt cgcacgtggg gatgtcctca tgacaccaaa tgggtcttgg gcgatcacag
     5401 cgattaatga acaaaaaccg aactttaaga ttgggacctt catgattcca ggaaaagaaa
     5461 aaggacaaag cttaaccgtt ggtgtgggag acttggcatg gtctatctca gccaccacca
     5521 aacatccaaa agaagccaat gcctttgtgg aatatatgac ccgtccagaa gtcatacaaa
     5581 aatactacga tgtggacgga tctccaacag cgatcgaagg ggtcaaacaa gcaggagaag
     5641 attcaccgct tgctggtatg accgaatatg cctttacgga tcgtcacttg gtctggttgc
     5701 aacaatactg gaccagtgaa gcagacttcc ataccttgac catgaactat gtcttgaccg
     5761 gtgataaaca aggcatggtc aatgatttga atgccttctt taacccgatg aaagcggatg
     5821 tggattagga gtagagagac tatgaaaaaa gtattacaaa aatattgggc atgggctttt
     5881 gtggtcatcc ccctcttgtt acaagcaatt ttcttctatg tgccgatgtt tcaaggagcc
     5941 ttttacagtt ttaccaactg gacaggattg acttataact acaaatttgt tggcttaaac
     6001 aactttaagc tcctcttcat ggatccaaaa ttcatgaatg cgattggctt taccgcaatc
     6061 attacgattg ccatggtggt tggtgagatt gcactcggga tcttcattgc gcgtgttttg
     6121 aattctaaaa tcaaaggcca aaccttcttc cgtgcttggt tcttcttccc agctgtttta
     6181 tctggtttga cagtggcttt gatcttcaag caagtcttca actacggtct tccagcgatt
     6241 gggaatgccc ttcatattga atttctccaa accagtcttt tagggactaa gtggggagca
     6301 atctttgcgg ctgtctttgt ccttctttgg caaggggtgg ctatgcccat catcatcttc
     6361 ctagctggtt tgcaatctat tccaactgag attacagagg cagcaaggat tgatggtgcg
     6421 actagcaagc aagttttctg gaacattgaa ttgccttact tgctaccaag tgtctctata
     6481 gtctttatcc tagccctaaa aggtgggctg actgcctttg atcaagtctt tgccatgacc
     6541 ggtggtggtc caaacaatgc cacaacctca cttgggctct tggtttataa ctatgccttt
     6601 aaaaacaacc aattcggtta tgccaatgcc attgccgtaa tcttgttctt cttaattgta
     6661 gtgatttcga tcatccaatt gagagtatct aagaaatttg aaatttaaga ggagaagcat
     6721 gatgaaacaa gatggaagaa aagccctgat tggcaaatac attctattga ttctaggatc
     6781 ggttctgatt ttagttccgc tccttgctac cctctttagt tccttcaaac ccactaagga
     6841 tattgtagat aatttctttg gctttccaac caacttcaca tgggacaact ttagccgtct
     6901 cttagctgat gggattggag gctattattg gaactttgtc gtcatcactg tcttgtcttt
     6961 acttgcagta atgatcttta tccctatggc agcctactcc atcgctcgca atatgagtaa
     7021 aagaaaagcc tttaccatca tgtataccct cttaatcctc ggaatcttcg tacctttcca
     7081 agtcatcatg attccgatta cggttatgat gagtaaactc ggtttggcta atacctttgg
     7141 tttgatcttg ctctacttga cctatgcgat tccacagacc ctctttctct atgttggcta
     7201 tatcaaaatc tcgattccag aaagtctgga tgaagcagca gagatcgatg gggctaatca
     7261 atttacaacc tatttccgca tcatcttccc aatgatgaaa ccgatgcatg cgacaaccat
     7321 gatcatcaat gccctttggt tctggaatga cttcatgttg ccactccttg tcttgaaccg
     7381 ggattccaaa atgtggactc tgcctttgtt ccaatacaac tacgcaggcc aatatttcaa
     7441 cgactacgga ccaagctttg cctcttacgt ggtcggcatt atcagtatca ccattgtcta
     7501 tctcttcttc caacgccata tcatttcagg aatgagcaac ggggcagtga agtaatactc
     7561 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgtacttgag tacggtaagg
     7621 tgaagctgac gtggtttgaa tttgattttc gaatagtata agaagagctc atggaatcta
     7681 tagtctttga cacagcggaa gagttcagct tgttgataat tctatgtaga aaacaagaaa
     7741 gtagtacttt gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa
     7801 aatgaatttg atttacgaag ccaagtcata tgagacttgg cttcaattag aaaaaggaga
     7861 gtaatgatgc caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat
     7921 aatcttaaag acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt
     7981 caccttttac catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgtc
     8041 gaagtggact cagcttttgg tgattgggag gatgttaagc gtttaggtga gaaatattat
     8101 cttatgtttg attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat
     8161 caagaaaaac atgaagccag tgaatttaaa gatctctttt taaactggga taagttttgg
     8221 ccagaaaacc gtccgataca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca
     8281 ccaaagcaag agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt
     8341 gaggagcaga ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc
     8401 attcagcact tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca
     8461 gtgaagaaat tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac
     8521 aaagttcgag atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac
     8581 tattcgattc agtttaaaat agcagaccat gattactatg tttattattt tgctcttcca
     8641 atggtgacac tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag
     8701 atgagcccga tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat
     8761 gtcaaggata tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt
     8821 ggagccaatg tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa
     8881 atcaattcaa cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt
     8941 ctaattcaag cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc
     9001 aagaatgact tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac
     9061 tatagcaacg aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat
     9121 ctattttctt tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag
     9181 acaccaacag ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca
     9241 gtagcagaaa ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta
     9301 acattttgaa gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct
     9361 ttgttttcaa attgctaaaa aagtggtaca atataggata gcttactatt atctgaatca
     9421 gctgatttgg agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg
     9481 ggttgtctag taaagagctg attttattgg gaattatcct gagtatcttt ttaccctttt
     9541 atctttttgt agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga
     9601 aaagtattct tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta
     9661 ctgttatatc cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc
     9721 tatttactat tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga
     9781 ttttgcagtt cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt
     9841 tccaaattgt gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc
     9901 agaaccgggc agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct
     9961 gtattatgat tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct
    10021 gtgtgattgc aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct
    10081 ttcctgctat tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg
    10141 ccttttggct tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt
    10201 tgggagttcg aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg
    10261 ctgggatggc cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc
    10321 actcttatcc tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata
    10381 cgattctgag ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg
    10441 ttcgcttgat gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc
    10501 tatctttcct tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc
    10561 agtcaggctt tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg
    10621 tatcggacat gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt
    10681 tttttatacg atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac
    10741 cggtgaatac aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc
    10801 tggggataga tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt
    10861 gaaatcgtag gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg
    10921 agaaatttta aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg
    10981 aattcggaat aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga
    11041 tacttctaca atattgttat aatttaattt gaattccaaa atcacattgt tccgtccgta
    11101 tttcatttta ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc
    11161 actgtagtct ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaatgaaaa
    11221 atttgtgcca acaagcctaa atattctgaa aatttgtttg atttttaatg gataatgtga
    11281 tataatggtt gtcaatctat aattcacata aacagaggag tagaaaatga aaaaaaatcg
    11341 tgtatttgct acagcaggtc ttgttttatt agcagcaggt gtacttgcag catgcagttc
    11401 ttcaaaatca tctgattcat cagcccctaa agcttatggc tatgtttata cagcagaccc
    11461 agaaaccttg gactacctga tttcaagtaa aaatagtaca acagtagtga cttcaaatgg
    11521 gattgatggt ttattcacta acgataatta cggtaatctt gctcctgcag ttgcagagga
    11581 ttgggaagtc tctaaggatg gtttgaccta cacttataag attcgtaaag gggttaaatg
    11641 gtttacctct gatggagaag aatatgcaga ggtgacggct aaagatttcg tgaacggttt
    11701 aaaacacgca gcagataaaa aatcagaagc tatgtattta gctgaaaatt cggttaaagg
    11761 cttggcagat tatctatcag gaacttcaac agatttttca acagttggtg tcaaggcggt
    11821 tgatgattat acgttacaat acactttgaa ccagcctgaa ccgttctgga actctaagtt
    11881 gacctattct attttctggc ctctgaatga agaattcgaa acatcaaaag gaagcgattt
    11941 tgctaaacca acagatccga catccttgct ttataatggt ccattcttgt tgaaagggtt
    12001 gactgcaaaa tcttctgtag agtttgtaaa aaatgagcaa tattgggata aagaaaatgt
    12061 ccacctagat actatcaatc tagcttacta tgatggatca gatcaggagt cgctagagcg
    12121 taacttcact agtggagctt atagttatgc ccgtctttac cctaccagct ccaactattc
    12181 taaggttgca gaagaataca aggacaatat ctattacaca caatcaggct ctgggattgc
    12241 tggtctgggt gtgaatattg atcgccaaag ttacaactat acttctaaaa ctacagattc
    12301 agagaaagta gctactaaga aggcattgct taacaaagat ttccgtcaag ccttgaattt
    12361 tgctcttgat cgctcagctt actcagctca aatcaatggt aaagatggag cagctttagc
    12421 agttcgtaat ttatttgtaa aaccagactt tgtttcagct ggtgagaaga cctttggtga
    12481 tttagtcgct gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga atttagctga
    12541 tgggcaggat ggtttattca atgctgacaa ggccaaggca gagtttgcga aagctaagaa
    12601 agctttagaa gcagacggcg ttcagtttcc tattcatctg gacgttccag tagaccaagc
    12661 atcaaaaaac tacatatctc gtattcagtc ctttaaacaa tctgtagaaa cagttcttgg
    12721 tgttgaaaat gtcgttgttg atattcaaca aatgacaagt gatgaattcc ttaatattac
    12781 ttactatgct gccaatgctt catctgagga ttgggatgta tcaggaggag tttcatgggg
    12841 tccagactat caagacccat ctacttacct ggatatttta aaaacaacta gcagtgaaac
    12901 tacaaaaaca tatttaggat ttgataatcc aaatagccct tcagtagttc aagttggttt
    12961 gaaagaatac gataaattag ttgatgaagc tgccagagag acaagcgact tgaatgtccg
    13021 ttatgaaaaa tatgcagcgg ctcaagcatg gttgacagat agttcactct ttattcctgc
    13081 tatggcttct tctggtgcag caccagtgct ttcacgaatt gttccattta ctggagcttc
    13141 tgcgcaaaca ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat tacaagataa
    13201 agtggtgact aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag aaaaagctga
    13261 atcaaatgag aaagctcaaa aagaattggc aagtcatgtg aagtaaataa tttctaatag
    13321 aactttctct ccatgaggag aaggttcttt tgggattttt aaaggaaata atatgaaaaa
    13381 atatattttt atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa cgactttgac
    13441 ctacacgatt atctatacct tggttcctcg aaaattgatt ttcaagcagg atcctaacta
    13501 taataaaatt gcgacaacgg ctgataaacg tgataactat gaaaatactg tgtttgagcg
    13561 tatgggctac attgagtatt acgatactaa agagttgcaa gaaaaggcaa gtagcatgga
    13621 ttcttctgta acagtagaag caaatgcgac caataaagct atttatgaaa agtacatcaa
    13681 tcaattaggt catggttgga ctttgggaga atttactgaa agtggtcaat tctatgctac
    13741 tcgtgaaatt ccaatttttg aacgtgtttt tcacttctat gctaacttga ttgacattga
    13801 ccatacaaat aaaatccaag accctgaaaa tccagacttg aaacgctacc ttcgttttga
    13861 aaatgatcca gctatcggat ggtcattggt cggttcagga actaaacata aatatctctt
    13921 gtactttaac agtcagttcc catttgttca tcaaaacttt gtgaacttga atttaggtga
    13981 ctcttaccca acctatgcta atacaccagt tcttcaggtt attactcaag gtcaaggaca
    14041 aaccaaaact gcccaagttc agttcccaac aggtaagaaa acgtcttctg taaatattta
    14101 ctcaagaacc tacaagtcac ctagtcaggc tgactctcgt gaagtagcta gctatgggaa
    14161 agatgatcct tatacagcga ctgaaagtaa ttaccaatat ccatctatga ttgtcagctc
    14221 tgctattact ggtttgattg gtttggttct tgcctatgct cttgccgtgc cacttggttc
    14281 agccatggct cgtttcaaga acacttggat tgatagcctc tcaacaggga ctttgacctt
    14341 cttgcttgct cttccaacga ttgccttggt ttacatcgtt cgattgattg gatcatctat
    14401 tgcccttcca gattcattcc ctatcttggg agctggagat tggcgttctt acgttttacc
    14461 agcagtcatc cttggtttgt tgggtgctcc tgttacagcc atttggattc gtcgttacat
    14521 gattgacttg caatctcaag actttgttcg tttcgctcgt gcaaaaggtt tgtctgaaaa
    14581 agaaatttca aacaaacaca tctttaaaaa tgccatggtt ccgctggttt caggaattcc
    14641 tggtgccatt attggggtta tcggtggtgc aacccttact gaaacagtct tcgccttccc
    14701 aggtatgggt aaaatgttga ttgactctgt aaaagcatct aataactcta tggtcgttgg
    14761 tcttgtcttc atctttacat gtatttctat cttctcacgt cttttgggag atatttggat
    14821 gactattatt gacccacgta ttaaattgac tgagaaagga ggcaaataat gtctacaatc
    14881 gataaagaaa aatttcagtt tgtaaaacgt gacgattttg cctctgaaac tattgatgcg
    14941 ccagcatatt cttactggaa atcagtgttt aaacaattta tgaagaaaaa atcaactgta
    15001 gtcatgttgg gaatcttggt agccatcatt ttgataagtt tcatctaccc aatgttttct
    15061 aagtttgatt tcaatgatgt cagcaaggta aacgacttta gtgttcgtta tatcaagcca
    15121 aatgcggagc attggttcgg tactgacagt aacggtaaat cgctctttga cggtgtctgg
    15181 ttcggagctc gtaactccat cctcatttct gtgattgcga cagtgattaa cttggttatc
    15241 ggtgtttttg tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt catgatggaa
    15301 gtttacaacg tcatctcaaa catcccacct cttttgattg ttattgtctt gacttactca
    15361 atcggagctg gattctggaa tctgattttt gccatgagcg taacaacatg gattggtatt
    15421 gccttcatga tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa cttggcgtca
    15481 cgtactttgg gaacaccaac cttgaagatt gttgccaaaa atatcatgcc tcaattggta
    15541 tctgttattg tgacaaccat gactcaaatg cttccaagct ttatctcata cgaagccttc
    15601 ttgtctttct tcggtcttgg attaccgatt acagtgccca gtttgggtcg tttgatttcg
    15661 gattattcac aaaacgtaac aaccaatgct tacttgttct ggattccatt gacaaccctt
    15721 gtcttggtat ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc tagtgatcca
    15781 cgtacacata gataggagta gaaatgacaa aagaaaaaaa tgtaattttg actgctcgcg
    15841 atattgtcgt ggaatttgac gttcgtgaca aagtattgac agccattcgc ggcgtttccc
    15901 ttgaactagt cgaaggagaa gtattagcct tggtaggtga gtcaggatca ggtaaatctg
    15961 ttttgacaaa gaccttcaca ggtatgctcg aagaaaatgg tcgcattgct caaggtagta
    16021 ttgactaccg tggtcaggac ttgacagctt tatcttctca caaggattgg gaacaaattc
    16081 gtggtgctaa gattgcgact atcttccagg acccaatgac tagtttggac cccattaaaa
    16141 caattggtag tcagattaca gaagttattg taaaacacca aggaaaaaca gctaaagaag
    16201 cgaaagaatt ggccattgac tacatgaata aggttggcat tccagatgca gatagacgtt
    16261 ttaatgaata cccattccaa tattctggag gaatgcgtca acgtatcgtt attgcgattg
    16321 cccttgcctg ccgacctgat gtcttgatct gtgatgagcc aacaactgcc ttggatgtaa
    16381 ctattcaagc tcagattatt gatttgctaa aatctttaca aaacgagtat catttcacaa
    16441 caatctttat tacccacgac cttggtgtgg tggcaagtat tgcggataag gtagcggtta
    16501 tgtatgcagg agaaatcgtt gagtatggaa cggttgagga agtcttctat gaccctcgcc
    16561 atccatatac atggagtctc ttgtctagct tgcctcagct tgctgatgat aaaggggatc
    16621 tttactcaat cccaggaaca cctccgtcac tttatactga cctgaaaggg gatgcttttg
    16681 ccttgcgttc tgactacgca atgcagattg acttcgaaca aaaagctcct caattctcag
    16741 tatcagagac acattgggct aaaacttggc ttcttcatga ggatgctcca aaagtagaaa
    16801 aaccagctgt gattgcaaat ctccatgata agatctgtga aaaaatggga tttgcccatc
    16861 tggctgacta ggaggaagga aatgtctgaa aaattagtag aaatcaaaga tttagaaatt
    16921 tccttcggtg aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt ctttatcaac
    16981 aagggagaaa ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac tattggtcgt
    17041 gctatcatcg gtctaaatga tacaagtaat ggagatatca tttttgatgg tcaaaagatt
    17101 aatggtaaga aatcgcgtga acaagctgcg gaattgattc gtcgaatcca gatgattttc
    17161 caagaccctg ccgcaagttt gaatgaacgt gcgactgttg attatattat ttctgaaggt
    17221 ctttacaatc accgtttatt taaggatgaa gaagaacgta aagagaaagt tcaaaatatt
    17281 atccgtgaag taggtcttct tgctgagcac ttgactcgtt accctcatga attctcaggc
    17341 ggtcaacgtc aacgtatcgg tattgcccgt gccttggtca tgcaaccaga ctttgttatt
    17401 gcagatgagc caatttcagc cttggacgtt tctgtacgtg cccaagtctt gaacttgctc
    17461 aaaaaattcc aaaaagagct cggcctgacc tatctcttca tcgcccatga cttgtcggtt
    17521 gttcgcttta tttcagatcg tatcgcagtt atttacaagg gtgttattgt agaggttgca
    17581 gaaacagaag aattgtttaa caatccaatt cacccatata ctcaagcctt gctttcagcg
    17641 gtaccaatcc cagatccaat cttggaacgt aagaaggtct tgaaggttta cgatccaagt
    17701 caacacgact atgagactga taagccatct atggtagaaa tccgtccagg tcactatgtt
    17761 tgggcgaacc aagccgaatt ggcacgttat caaaaaggac taaactagta atggttttat
    17821 aatttccatg tcaattttta tggaaattag gctctttgtc aactgtagtg ggttgaagtc
    17881 agctaagctc gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa agcgataaaa
    17941 atccgttttc tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg
    18001 atgagattat tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcgttgaca
    18061 atcttttctt tatctttgag gaaggtttta aagacagtct gaaaaagagg atgaacctgc
    18121 tttagattgt cctcaataag cccgaaaaat ttctctggtt ccttattctg gaagtgaaaa
    18181 agcaagagct gat
//
LOCUS       DAVDHZ010000044        16922 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000044 DAVDHZ010000000
VERSION     DAVDHZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.045"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(325..2583)
                     /gene="glgP"
                     /locus_tag="VUR46_001776"
     CDS             complement(325..2583)
                     /gene="glgP"
                     /locus_tag="VUR46_001776"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET5457148.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(2609..4126)
                     /gene="malQ"
                     /locus_tag="VUR46_001777"
     CDS             complement(2609..4126)
                     /gene="malQ"
                     /locus_tag="VUR46_001777"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET5457149.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            4676..5947
                     /locus_tag="VUR46_001778"
     CDS             4676..5947
                     /locus_tag="VUR46_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5457150.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6058..7350
                     /locus_tag="VUR46_001779"
     CDS             6058..7350
                     /locus_tag="VUR46_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5457151.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            7352..8194
                     /locus_tag="VUR46_001780"
     CDS             7352..8194
                     /locus_tag="VUR46_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5457152.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            8455..9255
                     /locus_tag="VUR46_001781"
     CDS             8455..9255
                     /locus_tag="VUR46_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET5457153.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTKELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFKTFKECYHFILNCL
                     GLPTLITLILGLFGQNMSNLITVQNILFVLYLVTIFYKTHFRDPDYHK"
     gene            9265..10251
                     /locus_tag="VUR46_001782"
     CDS             9265..10251
                     /locus_tag="VUR46_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5457154.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            10387..10467
                     /locus_tag="VUR46_001783"
                     /pseudo
     CDS             10387..10467
                     /locus_tag="VUR46_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10543..11484)
                     /locus_tag="VUR46_001784"
     CDS             complement(10543..11484)
                     /locus_tag="VUR46_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET5457155.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(11462..13225)
                     /gene="aspS"
                     /locus_tag="VUR46_001785"
     CDS             complement(11462..13225)
                     /gene="aspS"
                     /locus_tag="VUR46_001785"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET5457156.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(13416..13496)
                     /locus_tag="VUR46_001786"
                     /pseudo
     CDS             complement(13416..13496)
                     /locus_tag="VUR46_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(13532..13762)
                     /locus_tag="VUR46_001787"
     CDS             complement(13532..13762)
                     /locus_tag="VUR46_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457157.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(13780..14421)
                     /locus_tag="VUR46_001788"
     CDS             complement(13780..14421)
                     /locus_tag="VUR46_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5457158.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATSSLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKIGFNRFIWLPALIWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(14433..15167)
                     /locus_tag="VUR46_001789"
     CDS             complement(14433..15167)
                     /locus_tag="VUR46_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET5457159.1"
                     /translation="MKKRRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKILIP
                     WISAICLVLVFISILLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHINPQTFFLSFLLFVVFLVAQKYLFKTIAIVRQFDLA
                     FFSTPKDVLEYVNSYDEGERQANLEQSFRILFQLNQYVLPALYIFLFIISFLTGEIQL
                     LAFLLVGAIHIYINVMQLPMVKRYFK"
     gene            complement(15170..15367)
                     /locus_tag="VUR46_001790"
     CDS             complement(15170..15367)
                     /locus_tag="VUR46_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457160.1"
                     /translation="MNKYKVIYYVVVIALSVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(15367..15573)
                     /locus_tag="VUR46_001791"
     CDS             complement(15367..15573)
                     /locus_tag="VUR46_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5457161.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(15583..15897)
                     /locus_tag="VUR46_001792"
     CDS             complement(15583..15897)
                     /locus_tag="VUR46_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457162.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLEKKIKKLERKEKGNTEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(16357..>16922)
                     /locus_tag="VUR46_001793"
     CDS             complement(16357..>16922)
                     /locus_tag="VUR46_001793"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5457163.1"
                     /translation="TFTGTVGSVNVTVLFDKPVNAEKVTVKEITEKDLVDKISRQAGG
                     GSIRLFDLSLTKDGKETHVNEERTVRLALEGLGENVQVYHVKPDGQLELLDSKVEDGH
                     VIFRINHFSLFAIKTMSTKSNQETPSNQATPSTQAKSTPKETTKDATSKKTLPNTGTA
                     DSTALLAAAASTAILGLGLAGRRRKED"
BASE COUNT         5022 a         3682 c         3197 g         5021 t
ORIGIN      
        1 tactttatgt aagcgaatac aagagatatg aggtaaccaa ctacgaaaaa atataaggct
       61 gaagacagca aaaaccagca tttaaagcct tcactgtatc taggatttcc ctatttttag
      121 acaagattga cccaaatcca cagcatttaa aaaagcgaat ttcaatcgaa actcgctttt
      181 ttacaagatg tattagtata aatttgtatc ttatactcaa tgaaaatcaa agagcaaact
      241 aggaagctag ccgcaggttg ctcaaagcac cgctttgagg ttgcagataa agctgacgtg
      301 gtttgaagag attttcgaag agtattagtt caagtgccag atgtcttcat tatactgagc
      361 gattgtacgg tcagatgaga agaatcctgc tttagaaatg ttaacgatga ctttatccaa
      421 ccatgcgtca cggtcttcgt agtcagcaag catttgctct ttgactttga tgtagtcttc
      481 caaatcaaga agagtcatga accagtcttt gttgatcaat tcattgtaaa gacgttccaa
      541 gcgctctttg tttccagctg caagaactgc atcactaacg atgaagtcaa ccaatggttt
      601 gatagcttca cgagcgtaga attcgcttga tttgtaagct gcttttgcgt aaaggtcgat
      661 aacagtttct gaatcttcac cgaagatgta gatgttttct tctccaacca actcagcgat
      721 ttccacgtta gcaccgtcca tagtaccaag tgtcaaagct ccgttcaaca tgaatttcat
      781 gttaccagta cctgaagctt ctttagaagc aagtgagatt tgttctgaga tatcacatgc
      841 tgggataagg aaacttgctg cagtaacgtt gtagttttca accataacta cttgcaagtg
      901 tggagctact gctggatcgt tagcaataac ttctgacatg caaaggatta aatggataat
      961 gtcttgagcg attgtgtagg ctggagctgc tttaccacca aagaagattg tgattggacg
     1021 agcagggatg ttaccagctt tgatgtcaag gtatttgtgg atcacgtaca aagcgttcat
     1081 ttgttggcgt ttgtactcgt gaagacgttt gatttggata tcaaagatag aatttggatt
     1141 gatttccaca ccttggtgtt ctttcaagtg acgagccaat ttacgtttgt tgtgagcctt
     1201 gatgctttcc aatttttctt tgacagctgc tttgtcttca taagacaaaa gtttttcaag
     1261 ctcatctgct tcatggtgcc aaccatctcc aagaatctca tccaagtagt gagacaatct
     1321 tgggttagca tgcataagcc aacgacggaa agtgataccg tttgttttgt tgttgaactt
     1381 ttctgggtaa aggtcgtaga aggctttcaa ctcagaattt ttcaagattt cagtatggag
     1441 tgctgcaacc ccgttaacac tgtatccgta gtggatatcc atgtgagcca tgtgaacacg
     1501 tccgctctca tcgatgattt gaacagctgg atctttgtac tctgccttca cacgacggtc
     1561 caattcttcg atgattggta ccaagtgagg aaccacttct tgcaagaatt caagaggcca
     1621 tttttcaagc gcctcagcaa ggattgtgtg gttagtgtag gcagtcatgc tacgaacaat
     1681 tgagattgct tcgtcaagct cgataccacg tgcagtcaaa agacgaatca attcaggaat
     1741 caccattgat gggtgagtat cgttgatttg gacaactgcg tagtcagcaa ggtcatgcaa
     1801 gttgcttcct ttttcgattg cttcgtcgat gatcaattgc gcaccgtttg aaaccatgaa
     1861 gtattgttgg aagatacgga gcaattcacc ttgacggtca ctatcatctg ggtaaaggaa
     1921 gagagtcaag ttgcgagcga tatctgtctt gtcaaagttg ataccatctt taataataga
     1981 agaatcaact gaatccaagt caaacaaacg caagcggttt ttagtcgctg tttcataacc
     2041 agtaacatca atatcgtaaa gagttgatgt caaagtaaag tctgcaaatg gtacttggta
     2101 gctacggctt gagcgaacca accagttttg ctctgtcaac catgcatttg gaattgtttc
     2161 ttgttggttg tttttaagaa cttgttggaa aagaccaaag tggtagttaa gaccaacacc
     2221 gtcaccattc aaaccaagag tagcaattga gtcgataaag caggcagcca aacgtcccaa
     2281 accaccatta ccaagagatg gttccaattc aacttcttca acttcgatca agtctttacc
     2341 tgcagctgca agttcttttt taacatcgtc gtaaagacca aggttaatca agttgtttga
     2401 caagagttta ccaatcaaga actcagctga gatgtagtaa acttttttct taccagtgtt
     2461 gactggtttt tggctgcttg caagcttgct gtagttaaga agagcaaggt aaagctcttc
     2521 attgctacat tctgcaatgg ttttattgta acgattttgt acaaattctt gtagtgataa
     2581 catgtttagt tgtctcctga ttattgtctt atttctttaa atctaccaaa ttttcattaa
     2641 ttcggcgata aattgttgtc aagtcaagca aaccttcctc gacagctggt gtcaattgat
     2701 cttcagtcat acgccaagac cagtttccac caagggtaga tgggaagttc atacgagctg
     2761 cctcatccaa ttctagtaaa tcttgcatag tcgcaattgc cataaagcta actgatgaaa
     2821 atactgtacg aagcatagcg tgtaccactg tttcgtattc tttacggttc gtgtaacgag
     2881 ccatgtactc acgagtcgca tcatcaatct cattacggta ccaaccaaga accgtattgt
     2941 tatcgtgtgt tcctgtgtac ataactgagt tagcaggtgc caagtgtggg ctatcaatgc
     3001 tttcgtcttc tgggttgaag gcaaattgaa gaatcttcat tcctgggaag ccagtacgtt
     3061 cacgcaattc gatcacttca tctgtcatga agccaaggtc ttctgcgatg atgtttagct
     3121 caccaagttc ttccttaacg gctgcaaaaa gcttgtagcc tggacctttc acccactcac
     3181 caggtgctgc tgtatcggaa ccagcaggga tttcccaata agattcgaag ccacggaagt
     3241 ggtcgatacg aacgatatcg tagattttga agctttcacg caagcgttca atccaccatt
     3301 tgtagccgtc tttgtccatt gcttcccagt catagattgg gttaccccaa agctgaccag
     3361 ttacagaaaa ctcatctggt gggcatcctg cgatacaagt agccttacca ttgacatctg
     3421 ttttgaagag atgtggattt gcccacatat cacttgaatc ttccgctacg tagattggca
     3481 tgtccccaac gatttcaatg tggttgtcgt tagcgtaagc tttcaatttc aaccattgtt
     3541 ggaagaagaa gtattgagtc acacggtggt aaaccaactt gtctgccaat tgctcacgat
     3601 agctttcaag tgctgaagct ttacgagcac gagcatctgc atctggccat tcagtccaag
     3661 caagattgtc aaaatgctct ttgatagcca tatactcagc aaagagctca agccatgatt
     3721 ggttgtcttg agcaaatttc tcaaaatctt taacatctcc gacttcaaag aaacgtttca
     3781 ccgctttttc taaaagagga cgacgtgcat agtagatttt agcatagtca acttcagacg
     3841 catcgctacc aaagtcaact ccttcaaggt cacttgcttc caacaaacct tgctccacca
     3901 agatatctaa atcgataaaa tgagtgtttc ctgcgaaggc tgagaaagat tggtaaggag
     3961 agtccccgta actagttgct cctaatggaa ggatttgcca gtaacgttgt tttgtacgga
     4021 ccaagaaatc aacgaagtcg taagcacttt gaccaaatga tccgattccg taagctcctg
     4081 gaagagaaga gatgtgcatc aacacaccac tttgacgttt tttcataata gcacctcgtg
     4141 tgttaaaata atggaacgtt gcgtattttg cagacgcaaa cgtttgcgtt acttataagt
     4201 atactccttt tcaagcataa ttgcaagcgt ttttaaaaaa cttttttgat tatttttaag
     4261 gagactaact cattttagca aagataactt aaaactatct aatcctaaag tttgactctc
     4321 acgagacagt ctacaaagta caaaacctcc ttagggagct tgaatttata tgcaacaaag
     4381 cacaaacgtc tatagaaaat agatagggat tagaaccagg gaggtagccc ctcctggttt
     4441 ccctctttag acagattcca tatattttta ttaaaaatac tgtattctta tctatttcat
     4501 acttttcttc tattaaaatg caaaattatg ctatcaaatc aagcttaaaa attttttaaa
     4561 atttttacaa aaaatacttg caaccgtttt ctatttgtgc tatactaagc tcataaagga
     4621 aaacgtttgc gtttccttat caataaaact tgctattctt tgggaggaat acactatgtc
     4681 atctaaattt atgaagagca ctgcggtgct tgggactgtt acacttgcta gcttgctttt
     4741 ggtagcttgc ggaagcaaaa ctgctgataa gcctgctgat tctggttcat ctgaagtcaa
     4801 agaactcact gtatatgtag acgagggata taagagctat attgaagagg ttgctaaagc
     4861 ttatgaaaaa gaagctggag taaaaatcac tcttaaaact ggtgatgctc taggaggtct
     4921 tgataaactt tctcttgaca accaatctgg taatgtccct gatgttatga tggctccata
     4981 cgaccgtgta ggtagccttg gttctgacgg acaactttca gaagtgaaat tgagcgatgg
     5041 tgctaaaaca gacgacacaa ctaaatctct tgtaacagct gctaatggta aagtttacgg
     5101 tgctcctgcc gttatcgagt cacttgttat gtactacaac aaagacttgg taaaagacgc
     5161 tccaaaaaca tttgctgact tggaaaacct tgctaaagat agcaaatacg cattcgctgg
     5221 tgaagatggt aaaactactg ccttcctagc tgactggaca aacttctact atacatatgg
     5281 acttcttgcc ggtaacggtg cttacgtctt tggccaaaac ggtaaagacg ctaaagacat
     5341 cggtcttgca aacgacggtt ctatcgtagg tatcaactac gctaaatctt ggtacgaaaa
     5401 atggcctaaa ggtatgcaag atacagaagg tgctggaaac ttaatccaaa ctcaattcca
     5461 agaaggtaaa acagctgcta tcatcgacgg accttggaaa gctcaagcct ttaaagatgc
     5521 taaagtaaac tacggagttg caactatccc aactcttcca aatggaaaag aatatgctgc
     5581 attcggtggt ggtaaagctt gggtcattcc tcaagccgtt aagaaccttg aagcttctca
     5641 aaaatttgta gacttccttg ttgcaactga acaacaaaaa gtattatatg ataagactaa
     5701 cgaaatccca gctaatactg aggctcgttc atacgctgaa ggtaaaaacg atgagttgac
     5761 aacagctgtt atcaaacagt tcaagaacac tcaaccactg ccaaacatct ctcaaatgtc
     5821 tgcagtttgg gatccagcga aaaatatgct ctttgatgct gtaagtggtc aaaaagatgc
     5881 taaaacagct gctaacgatg ctgtaacatt gatcaaagaa acaatcaaac aaaaatttgg
     5941 tgaataaaaa atttgttcaa ggggggtgga aatcaaatcc ccctttgaat ttatcaatag
     6001 agacacaaat aatttagctt tcttataaaa aagtagtatc ctatgaaagg agttaatatg
     6061 gaaaagcaac aacctagtaa agcagccctg ctgtctatca ttcctgggtt aggacagatt
     6121 tacaataaac aaaaagccaa aggttttatc ttccttggtg taaccatcgt atttgtcctt
     6181 tacttcctag cacttgcaac ccctgaattg agcaacctca tcactcttgg tgacaaacca
     6241 ggtcgtgata attccctctt tatgctgatt cgtggtgcct tccatctaat ctttgtaatc
     6301 gtttatgtac tcttttattt ctcaaatatc aaagatgcac atacgattgc aaaacgcatt
     6361 aacaatggaa ttccagttcc acgcacactc aaagacatga tcaaagggat ttatgaaaat
     6421 ggcttccctt acctcttgat cattccatct tatgttgcca tgaccttcgc gattatcttc
     6481 ccagttatcg taaccttgat gatcgccttt accaactacg acttccaaca cttgccacca
     6541 aacaagttgt tggactgggt tggtttgacc aactttacaa acatttggag cttgagtacc
     6601 ttccgttctg cctttggttc tgttctttct tggactatca tttgggcttt ggcagcttct
     6661 actttacaaa tcgtaattgg tatcttcaca gctatcattg ctaaccaacc atttatcaaa
     6721 ggaaaacgta tctttggtgt tattttcctt cttccttggg ctgtcccagc cttcatcact
     6781 atcttgacat tctcaaacat gtttaacgat agtgtcggtg ctatcaacac tcaagtattg
     6841 ccaatcttgg ctaaattcct tcctttcctt gatggagctc ttattccttg gaaaacagac
     6901 ccaacttgga ctaagattgc cttgattatg atgcaaggtt ggctcggatt cccatacatc
     6961 tacgttctga ccttgggtat cttgcaatct attcctaacg acctttacga agcagcttat
     7021 attgacggtg ccaacgcttg gcaaaaattc cgcaacatca ctttcccaat gatcttggct
     7081 gttgcggcac ctactttgat tagccaatac accttcaact ttaacaactt ctctatcatg
     7141 tacctcttca atggtggagg acctggtagt gtcggaggtg gagctggttc aaccgatatc
     7201 ttgatctcat ggatctaccg tttgacaaca ggtacatctc ctcaatactc aatggcggca
     7261 gctgttacct tgatcatctc tatcattgtc atttcaatct ctatgatcgc attcaagaaa
     7321 ctacacgcat ttgatatgga ggacgtctaa gatgaataac tcaattaaac tcaaacgtag
     7381 actgactcaa agccttactt acctttacct gattggtcta tcaattgtaa ttatctatcc
     7441 actgttgatt accattatgt cagcctttaa agcaggtaac gtctcagcct ttaaactaga
     7501 tactaatatc gacctcaatt ttgataactt taaaggcctc ttcactgaaa ccttgtacgg
     7561 tacttggtac ctcaacactt tgattatcgc cttaattacc atggctgttc aaacaagtat
     7621 catcgtactt gctggttatg cttacagccg ttacaacttc ttggctcgta aacaaagttt
     7681 ggtcttcttc ttgatcatcc aaatggtgcc aactatggcc gctttgacag ccttcttcgt
     7741 tatggcgctt atgttgaacg cccttaacca caactggttc ctcatcttcc tctacgttgg
     7801 tggtggtatc ccgatgaatg cttggctcat gaaaggctac ttcgatacag tgccaatgtc
     7861 tttagacgaa tctgcaaaac tagacggtgc aggacacttc cgccgcttct ggcaaattgt
     7921 tcttccactt gttcgcccaa tggttgccgt acaagctctc tgggccttca tgggaccttt
     7981 cggggactac atcctctcta gtttcttgct tcgtgagaaa gaatacttta ctgttgccgt
     8041 aggtctccaa accttcgtta acaatgcgaa aaacttgaag attgcctact tctcagcagg
     8101 tgctatcctc atcgcccttc caatctgtat tctcttcttc ttcctacaaa agaactttgt
     8161 ttcaggactt acaagtggtg gcgacaaggg ataatttatc cccaccaccc tttttcattt
     8221 tatactcttc gaaaatctct tcaaaccacg tcagctttat ctccaacctc aaagttgtgc
     8281 tttgagcaac ctgcggctag cttcctagtt tgcactttga ttttcattga ctattagcga
     8341 ttgtcactgt aaataatatc cttgtagcaa gcaatttacc ccctagactt gaaataaagc
     8401 gcatttctct atataataat actcatatag aaaacacctt ttagaaagat acctatgctt
     8461 ccatatccat tttcctattt ttcaagtatt tgggggtttc gtaagcccct gtccaaacgt
     8521 ttcgggctca actggtttca acttctcttt accagtatct tccttatcag cttgtctatg
     8581 gtacccattg ctatccaaaa cagctcccag gagacctatc cgctagaaac ttttatcgat
     8641 aatgtctatg aacctctgac agataaggtt gtccaggatc tctctgaaca tgctacaatt
     8701 gtcgatggca cattaactta tactggaaca gctagtcaag ccccttctgt tgtgattggt
     8761 ccaagtcaaa tcaaggaatt acctaaggac ttgcaactgc atttcgacac aaaagaactg
     8821 gtcatcagca aggaaagcaa ggaattgacc cgtatctctt accgagcgat tcagactgag
     8881 agtttcaaaa gtaaagacag cttgacccaa gcaatttcta aagactggta ccaacagaat
     8941 cgtgtctata tcagtctctt cctagttctc ggtgcgagct tcctctttgg tttgaatttc
     9001 tttatcgtct ctctaggggc gagtcttctc ctttatatca ctaagaaatc acgcctcttt
     9061 tcatttaaaa cctttaaaga gtgctaccat tttatcttga actgtttagg attgccgact
     9121 ctgattacgc ttattttggg attgtttggc caaaatatgt caaacctcat cactgtacaa
     9181 aacattcttt ttgtccttta tctggtcact atcttttata aaacgcattt ccgtgatcca
     9241 gattaccata aataggagat ttttatgccc gttacgatta aagacgtggc caaggctgct
     9301 ggtgtttccc cttcaaccgt aacccgtgtt attcaaaata aatcaaccat tagcgacgaa
     9361 actaaaaaac gcgttcgcaa ggcgatgaag gagctcaatt accaccccaa cctcaatgct
     9421 cgtagcttgg taagcagcta tactcaggtg attggtttgg ttcttcctga tgactcagac
     9481 gccttctatc aaaatccttt cttcccatca gtcctacgcg gcatctctca agtcgcatct
     9541 gaaaaccact atgccattca gatagcaaca gggaaagatg agaaggagcg tctcaacgct
     9601 atttcacaaa tggtctacgg caagcgtgta gatgggctaa tctttctcta tgcccaagaa
     9661 gaagaccctc tcgtaaaact cgtcgcagaa gaacagttcc ccttccttat cctaggtaaa
     9721 tctctatctc ctttcatccc acttgtcgac aacgacaatg ttcaagctgg ttttgatgcg
     9781 actgaatatt tcatcaaaaa aggctgcaaa cgcattgcct ttatcggagg aagtaaaaag
     9841 ctcttcgtga ccaaagaccg tttaacaggc tatgaacagg cgcttaaaca ttacaaactt
     9901 accactgaca acaatcgcat ctactttgcc gacgagtttc tggaagaaaa gggctataaa
     9961 tttagcaagc gattattcaa gcacgatcca caaattgatg ctatcatcac aaccgatagc
    10021 ctcctagctg aaggtgtttg taactatatt gccaaacacc agctggatgt ccctgttctc
    10081 agctttgact cggttaatcc caagctcaac ttggcagcct atgtcgatat caatagttta
    10141 gagcttggtc gtgtttccct tgaaactatt ctccagatta ttaatgataa taaaaacaat
    10201 aaacaaattt gttaccgtca attgatcgcc cacaaaatta tcgaaaaata agagactggg
    10261 caaagagtcg ttaaaagcaa aaacgcatac tatcaggtat tgaaaaaact tgatactatg
    10321 cgttttattg tgggaagatt tacttccttt tctactgaaa ttgagtcttt tcccaagatc
    10381 tttttatact caatgaaaat caaagtgcaa actaggaagc tagccgcagg ttgctcaaaa
    10441 cactgttttg aggttgtgga tagaactgac gaagtcagta accataccta cggcaaggcg
    10501 acgctgacgt ggtttgaaga gattttcgaa gagtattaat cactaattat ctatctcaac
    10561 aaatcttcct agaatatgaa cattttccga gacagagaca aaggagcttg gatccacttg
    10621 tgtcataatc tgtttaaatt cattaaactc tgcacgtgta atgacagtga ttaaaactgc
    10681 ctttctctcg tgattatagg ttccttctgc atcgtggatc atggttgctc cgcggtgcaa
    10741 ttttttatgg attttttcaa ttaccttctc tggatgattt gtcacaatca tggcctgcat
    10801 acgcttttgc ttagtaaaga ctgcgtctgt cacacggcta gagacaaaga tggtaatcat
    10861 agaataaaga gcgtatttcc aaccaaaggt caaacctgct atcagcatga tagttccatt
    10921 taccaagaaa gaaatactac cgacattctt acccgttttc ttgcgaatag tcaggctgac
    10981 gatatccgtc ccaccactgg agatattgtt tcgaagagca aaaccaatcc ccaaacccat
    11041 aacaacaccc ccaaaaaggg aattgataat gggatcctcc gtcaaggttg ccacagggac
    11101 aaactggata aagaaggaac tcatagatac cgtgataaag gtaaagacgg tgaacttatg
    11161 gccaatctga taccaagcta agaccatcaa agggaagtta atggcgtaga agcttagcga
    11221 aatcggaata tgaaaaccaa accagtgatt actcaaggca gagataatct gtgccagacc
    11281 tgttgcacca ctcgaataca catgccctgg ttggaaaaag aaattaactg ctactgctga
    11341 taaaaaacca tagaccagag aggccgaaat cttctcatca tacttttctc gagagatact
    11401 ttgtaagaca cgtaaaattt ttatctgata agcaaagcgg cgcagataat agcgccaccg
    11461 cttaattcgt tttgtttgtt tcatcttctt ctacttgtaa gctgagttcc tctagttgtt
    11521 tgagagcgac tgttgatgga gcttgtgtca ttgggtcagt tgccttgttg ttcttaggaa
    11581 aggcaatgac ttcacggata ttttcttctc cagcaagcaa catgacaaag cggtcaagcc
    11641 cgatagccaa accaccgtgt ggtgggaaac catagtccat ggcttcaaga aggaaaccaa
    11701 actggtcatt ggcttcttca gttgagaaac caagagcctt gaacatgcgt tcttgaaggt
    11761 ctttttggtt gatacgaagg ctaccaccac caagctcata accgttcaag acgatatcgt
    11821 aagcaatggc acgaacctta gccaaatcac cttctaattc gtgagcagtc tcttcctgtg
    11881 gaagtgtgaa tggatggtgg gcgctcatgt agcggccttc ttcttcagac cattcaaaca
    11941 tcggccagtc aaccacccaa aggaagttga acttatcatt atcaatcaag ccaagctctt
    12001 tagcaatacg tccacgaagg gcacccagtg ttgcattagc cacttcaagc gtatccgcca
    12061 caaagagaac caagtcctta tcttcaagag caagcgctgt tgtcaattct tcttggatac
    12121 cagtcaagaa cttggcaact ggtccgttta attctccatc aaccaccttg acccaagcaa
    12181 gacctttggc accatactgt ttggctactt ccgtcatctt gtcgatgtct ttacgtgaat
    12241 agttgtccgc agctcctttg accacaatcg cttttacagc aggtgcttct gaaaagactt
    12301 taaagtctac acctttgacc acttctgtca agtcctgaag caacatgtca aaacgagtat
    12361 ctggcttgtc agaaccgtaa agagccatag catcatcgta tttcatacga gggaacggta
    12421 gcgttacttc gatgcctttt gtttccttca tcacgcgcgc gatcaagcct tctgtaatat
    12481 cttggatttc ttgctcagta aggaaggacg tttccaagtc gacctgagta aattcaggct
    12541 ggcggtctcc acgcaagtcc tcgtcacgga aacatttaac gatttggtag taacggtcaa
    12601 aaccagcatt catcaagagc tgtttcgtga tttgtggact ttgaggaaga gcgtaaaaat
    12661 gccccttatt aacacgagac ggcactaaat aatcacgcgc cccttcaggc gttgacttag
    12721 aaaggaatgg tgtctccacg tcgataaact ccaactcatc caaatagttg cggatagagt
    12781 gggtcacctt ggcacgaagt ttaagatttt ccaacatttc tggacgacga aggtcaaggt
    12841 aacggtaacg caaacgtgta tcgtcatttg cctcaatgcc atccttaatc tcaaatggtg
    12901 ttgtcttagc tgtgttaagc acaataagag ctgtcacgtt taactcaacc gcaccagttg
    12961 gcaacttatc attggcttgc tcacgcgcag cgacctgacc agtcacctca ataacaaatt
    13021 cgctacgaag gctttcagct gttgccataa cctctgcaga tactttttca gggttgataa
    13081 ccaactgcat gattccttca cggtcacgaa gatcgataaa gatcaaacca ccaaggtcac
    13141 gacgacggcc aacccatcct ttcaaggtta tttcttgtcc gatgtgttcc tcacgaacac
    13201 gaccagcata catactacgt ttcattattt ctctcctctt ttattctgtt actattttac
    13261 cataaaagcg caggctcttc atgaaaatca tcagaaaagt ttgccagtct ttaaaagtca
    13321 ggtgaaagcc ctaaaaatta gcgctaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    13381 gtcgccttac cgtaggtatg gttactgact tcgtcagttc tatccacaac ctcaaaacag
    13441 tgttttgagc aacctgcggt tagcttccta gtttgctctt tgattttcat tgagtataat
    13501 acaaaaatcc gatgaacttc accggactct cttattttga atttttgcct gctttacgct
    13561 tttcagcaat ttcggctgcc tttcgaggca agacaatttc cgttatgtaa gccgtcccaa
    13621 aacgcagtac acctgcaata ggagcaaaga caactgctag atagttatag aagaaatcgc
    13681 ctttgaaggc ataagctagc gctccaatga tgaaaaatag aacaactgct tgaatcactg
    13741 ctaataaaat tactcgtttc atgtgacctc ctgactctat tatagcatga gaatcatcaa
    13801 aaagccgact aaattattca aagcgtgaag agaaatactg tagaccagac cttttctgct
    13861 aacgtaagcc aaacccaaac taaaaccaag gctaaaatag acaaaaaatt gttgcacatc
    13921 acctggaaaa tgaatcaagg caaatagaag actagatacc agaagaaaaa tcagggttcg
    13981 tttactattg tcctgcttag gaaagagata gcgtgctaac atccctctaa aaacaatctc
    14041 ttccgtcaaa ggagcaaaaa taaccacagc aaaaaatgag aaaagtggtt gagacaaggt
    14101 caagtctgtc gctatttgtt gatttactga aggatcatct ggcaagaaga attgaacgac
    14161 cagagataag aaccaaatca aggcaggaag ccaaataaat cggttaaagc cgatcttctc
    14221 aatatgaaca ggagctttct gataccattt gtaaatgccg tacacataaa ctccagccaa
    14281 ggccacataa agcaaggtaa cagcataggg tgaagcccct aaggcaagcg aagaggtcgc
    14341 cagcccctga ataaagccat agataaagaa aaaggataga agggctagaa gaaaccagcc
    14401 aaggttttta agtagtttca tagataactc ctttatttga aataacgttt taccataggt
    14461 aactgcatca cattgatata aatatggatt gctcctacaa gcaagaaggc tagtaactga
    14521 atctctcctg tcaagaaaga aatgataaaa agaaaaatat ataaggctgg taagacatac
    14581 tgatttaatt ggaataaaat ccgaaaactc tgttctaaat tagcttgtcg ctccccttca
    14641 tcataagaat ttacatactc taagacatcc tttggtgttg agaaaaatgc caaatcaaac
    14701 tgacgaacaa tcgcaatggt cttaaaaaga tatttttgag cgactaagaa taccacaaag
    14761 agtaagaaag aaaggaaaaa tgtttgaggg tttatatgca atataatcac ctcacttaat
    14821 gaaataaaaa tagccaatgg aatcgctaca cctgtaatat taaaagcaat ggttccaaac
    14881 tcaagattcc gatacatttg cacataatag gtttcattca gatcatcatc catttcctct
    14941 tgatacaagg agtgaaattt tctgcttttc tttaggaaat tgaaagtcaa aagaatgcta
    15001 atgaaaacta atactaaaca aatagctgat atccatggta tcaagatttt tacatctaaa
    15061 ataatttcgt gagattcgac acgcgcttta aacatcccta caaacatgcc caagaaacct
    15121 cccaagacaa tagacatcaa aaataacaat ctacgtctct ttttcatatt cattctcctt
    15181 tttcacttgc tagatttttg gatttctttt caatccattc aattactggg atgagagcaa
    15241 agtagaccca aacaaattgg tcgctttgat agggattaaa ccagcttagg tccatcccaa
    15301 tcagtagaaa tacgctgact gataaagcta tgaccactac ataataaatc actttatact
    15361 tgttcatcac tcgtcctcct ccaagcgaaa taccgattcg actgtttcgt tgaaaatttg
    15421 agatattttc agggcaatga taatggacgg ggtgtactca tcccgttcta gtaggctaat
    15481 ggtctgtctg gaaactcctg ccagcttggc taggtcggtt tgattgagac catcgcgagc
    15541 tctaagctct tttagacgat tttttagttg catgttacac acctactctc cgtcaaattc
    15601 aacggtttga atatcctcaa tacgttgcaa cttgaatttt tcttttcccg tattatctac
    15661 acgtcgtagc tttacccatt cctcatcaac atccacaact tcccagttat ctggcccaat
    15721 atacactccc gttataattg gttcctttcc aatcatttct tgtaataatc tcgacatttc
    15781 tgtgtttcct ttctcttttc gctcaagttt tttgattttc ttctctagtt tcttgatttt
    15841 tttagaatta ttagaataaa agaaaatcat aaatagtata aatactagta cccacattat
    15901 aactcctttc tgcttcctat ttcttaactt gaattcattg taacacctct ttttcttttt
    15961 gtaaaagaaa aagaggctgg gacaaaaatc ataaaaaggt atcctatcag gtgttcagaa
    16021 accttggtag gatgcctttt ataatggaaa gatttactgg attttctcct caaattgata
    16081 ctcaatgaaa atcaaaacct aaactaggaa gctggctgga taggactgac caagtcatca
    16141 cagacctaga gcaaggcgac gctgacctga tttgctcctt gatttttgaa gagtatagat
    16201 tcttaaaatg gatagataag acaaaaaaaa caaacaagac cgtattctga gtatcagaaa
    16261 actcgtcttg ttcgtttttt atatttaagg ttagactttt atcccaggtt cttagctctg
    16321 ttaggcaagg ctagagggga cagagggtct tttcccttaa tcttctttac gacgacgtcc
    16381 tgctagacca agtcctaaga tagcagtgct tgctgctgca gccagcaagg ctgttgaatc
    16441 agcagttcct gtatttggca atgttttctt gcttgtagca tccttggtcg tttctttagg
    16501 agtcgatttc gcttgagtac ttggagttgc ttggttagaa ggtgtctcct gattagactt
    16561 agtagacata gtcttaatag caaacaagct gaaatgattg attctaaaga tgacatgccc
    16621 atcttctact ttagaatcaa gaagttcgag ttgaccatct ggtttcacat ggtagacttg
    16681 aacattctct ccaagacctt caagcgcaag acgaacagtc cgctcctcat ttacatgtgt
    16741 ttccttgcca tcttttgtta aggataggtc aaataggcga atagatcctc cacctgcttg
    16801 gcgactgatc ttatcaacaa gatccttttc agtaatctcc ttgacggtca ctttttctgc
    16861 attaaccggc ttgtcaaata agacggtcac atttacactt ccaactgtgc ctgtaaaggt
    16921 tt
//
LOCUS       DAVDHZ010000045        16750 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000045 DAVDHZ010000000
VERSION     DAVDHZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.046"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            38..1756
                     /locus_tag="VUR46_001794"
     CDS             38..1756
                     /locus_tag="VUR46_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET5457164.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLTRRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            1867..2214
                     /locus_tag="VUR46_001795"
     CDS             1867..2214
                     /locus_tag="VUR46_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET5457165.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(2492..3328)
                     /locus_tag="VUR46_001796"
     CDS             complement(2492..3328)
                     /locus_tag="VUR46_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5457166.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYVDF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(3341..3970)
                     /locus_tag="VUR46_001797"
     CDS             complement(3341..3970)
                     /locus_tag="VUR46_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5457167.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(3980..4621)
                     /locus_tag="VUR46_001798"
     CDS             complement(3980..4621)
                     /locus_tag="VUR46_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5457168.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(4767..5996)
                     /locus_tag="VUR46_001799"
     CDS             complement(4767..5996)
                     /locus_tag="VUR46_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET5457169.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(5986..7152)
                     /locus_tag="VUR46_001800"
     CDS             complement(5986..7152)
                     /locus_tag="VUR46_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET5457170.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAISIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VWASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFMPTKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFMIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVISGLYELEGEEVKSEQ"
     gene            7296..8309
                     /locus_tag="VUR46_001801"
     CDS             7296..8309
                     /locus_tag="VUR46_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET5457171.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKTGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIRLSTDGQYLYASNRGHNSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIAVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(8355..8774)
                     /locus_tag="VUR46_001802"
     CDS             complement(8355..8774)
                     /locus_tag="VUR46_001802"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET5457172.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDEDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(8785..10191)
                     /gene="atpD"
                     /locus_tag="VUR46_001803"
     CDS             complement(8785..10191)
                     /gene="atpD"
                     /locus_tag="VUR46_001803"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET5457173.1"
                     /translation="MSSGKIAQVMGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKILVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(10277..11155)
                     /locus_tag="VUR46_001804"
     CDS             complement(10277..11155)
                     /locus_tag="VUR46_001804"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET5457174.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(11171..12676)
                     /locus_tag="VUR46_001805"
     CDS             complement(11171..12676)
                     /locus_tag="VUR46_001805"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET5457175.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENAMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(12691..13227)
                     /locus_tag="VUR46_001806"
     CDS             complement(12691..13227)
                     /locus_tag="VUR46_001806"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET5457176.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAYPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(13227..13721)
                     /gene="atpF"
                     /locus_tag="VUR46_001807"
     CDS             complement(13227..13721)
                     /gene="atpF"
                     /locus_tag="VUR46_001807"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET5457177.1"
                     /translation="MHVTVGELIGNFVLITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(13735..14451)
                     /gene="atpB"
                     /locus_tag="VUR46_001808"
     CDS             complement(13735..14451)
                     /gene="atpB"
                     /locus_tag="VUR46_001808"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET5457178.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(14486..14686)
                     /locus_tag="VUR46_001809"
     CDS             complement(14486..14686)
                     /locus_tag="VUR46_001809"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET5457179.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(14761..15768)
                     /locus_tag="VUR46_001810"
     CDS             complement(14761..15768)
                     /locus_tag="VUR46_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET5457180.1"
                     /translation="MQNYYTTKGKHLTIDSRCLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGCFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHRGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRSKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            complement(16225..16587)
                     /locus_tag="VUR46_001811"
     CDS             complement(16225..16587)
                     /locus_tag="VUR46_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457181.1"
                     /translation="MENKESHKSQEIGNLLRVYNRSKREETESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYL"
BASE COUNT         5087 a         3671 c         3037 g         4955 t
ORIGIN      
        1 aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag aaaattacca
       61 gaaatgggtt gattttgtgg agcttcctga ctaccttcgt caagatttgg aaaatatgga
      121 cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg caggtatgcg
      181 tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc aagctactga
      241 aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg gtgtcgcaat
      301 tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg cagttcttgc
      361 taaacacggc atcaaatctt acgtatttga aagccttcgt ccgactccag aactatcatt
      421 tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc acaaccctgc
      481 tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc cacacgatgc
      541 ggacgctttg actacttata tccgtgcaat cgaaaaccca tttgcagttg aagttgctga
      601 tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagctg ttgacataga
      661 ataccttaaa gaggttaagg acataaacat caacccagcc ttgattgaag aatttggtaa
      721 agacatgaag attgtctaca caccacttca tggtactggt gaaatgttga ctcgtcgtgc
      781 tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa ctgctgaccc
      841 agacttctca actgtaacat ctccaaaccc agaaagccaa gcagcctttg cccttgctga
      901 agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag acgctgaccg
      961 tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag gtaaccaaat
     1021 cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa ctcttcctga
     1081 aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga ttgctgaaag
     1141 ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg aaaaaatcca
     1201 agaattcgaa gaaaaacaca accacactta catgatggga tttgaagaaa gcttcggtta
     1261 cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg tcgttgctga
     1321 acttgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg aagaaatcta
     1381 taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag gtgtcgatgg
     1441 tgctgaacaa atcaaagcga ttatggctaa attccgcaac aatgctccaa cagaatggaa
     1501 cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg ttgctgacgg
     1561 tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac ttgctgacgg
     1621 ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct acattgcagt
     1681 tgtaggggaa accaacgaag aatcacaagc taagattact aacatcgaag cagaaatcaa
     1741 tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc ttttttcgta
     1801 tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg aaagcgaggt
     1861 aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac agttgtgcgt
     1921 gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg caaaacttgc
     1981 ccttactgcc gtaaatttgc aggtacattg tcaggtgtcg tagctgaaac caaagctcac
     2041 atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc attccgctca
     2101 cgttatggaa tcccaactgt accaggtttt gttcatatta cagatggaca aatcaacgtc
     2161 cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgtaggatt gtaaaaaatc
     2221 agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac cttgatatta
     2281 tgcgttttat tgttcctaaa acagttacat cagcatttca ttacagaaca ttttaatttt
     2341 ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt ccatattcaa
     2401 ttatccagat tcaatcgcta ttatcgtttt cctagattac aaaaaaacta cgttttgcta
     2461 atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact tctttggttg
     2521 ctacatcttc tccaaaccat ttttggctga tttcttggaa cttgccgtcc ttgtaaagac
     2581 tagaaaaagc ttcatttatc ttcttaacca agtttgtatc ttccttacgg gctccaaccg
     2641 caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa acaccttctg
     2701 cttctaaata atagtttgca tagacacggt caatcaatag accatcaatt cgatcgtttt
     2761 tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa
     2821 tattcttcaa aatttctgga tttgcttcaa agtccacata accagatgaa ccagcttgag
     2881 ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat ttcttcgtaa
     2941 ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca cggcgttcgt
     3001 ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat tcagcttctt
     3061 tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca aaaacagctg
     3121 tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat cccattggaa
     3181 caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt gaccaattat
     3241 ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca gtcatcagac
     3301 tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt tctactttca
     3361 ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca atctgggtca
     3421 tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat tctggatcca
     3481 gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata gcacgcgcca
     3541 aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggcctct gcgtgtcctc
     3601 ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc tgcttcattc
     3661 ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga ggaaatagtt
     3721 gaaaatcttg gaagacaaat cccagtagat tgcgcttctg caattcatcc agctctaaag
     3781 gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacctgca agcatacgta
     3841 aaagagttgt cttacctcca ccagaaggtc caacgatagc caggatttgc ttttcaggaa
     3901 tacttagact gaaattagac aggatttgtt tgtctccaaa gactttattg atatttcgta
     3961 attctaacat ggcagcctcc tatctataat aactatactt cttctcaact tttttggaaa
     4021 taattgtcac aatcccaatc aaaatcaaat aaatggctcc tgccaagaac ataggaacta
     4081 gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa attccgagag
     4141 catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca ctaggaagaa
     4201 cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg ctaaacttca
     4261 agaccttggc ggcctcatac tgtcctcttg gaatagtgtc aattccccca cggaaaattt
     4321 ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga aggcggtcta
     4381 aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag agtaaggggg
     4441 ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc caatggactt
     4501 gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga
     4561 cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat aaataagaca
     4621 tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag attaccaagt
     4681 atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa aagagataaa
     4741 ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg catttgcaca
     4801 tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc
     4861 aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt caaatctcct
     4921 gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg ataagaacga
     4981 gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc tagaatatcc
     5041 tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc
     5101 tcagcgtctt cttttgcagc aagaagataa ttttctgcac cactagcatc atgcaattca
     5161 taagaaaatt gtgaagcagc cagcaagagg cgagtttcaa agggattttt ctctaatcct
     5221 tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc ctgactgtac
     5281 ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg
     5341 gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc tgttaagtca
     5401 tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa tttccctaac
     5461 tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag
     5521 cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa ctcactatcc
     5581 aactctgcca aacccaacat caagagagaa tcctctgagt aggtcaaggc ctccaataat
     5641 ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt caaaaccaaa
     5701 gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa ggcttcttct
     5761 atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg aaaatcctct
     5821 acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc aagataagtt
     5881 gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa ataatactca
     5941 gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt gttcactctt
     6001 gacttcctca ccctctaatt catataggcc actgattacc ttataccatt cgaaaatggc
     6061 tgaaatgaca accttagcag aggcataaac cggaataccg agcaagactc cccagatacc
     6121 aaacatggat cctgaagtta gcaagacaaa gagaacatta atgggatgga tgtttaattg
     6181 acttcccaaa atcaatggag aaacaaaacg gccttcaata gtttgttcta cgataaagac
     6241 aatcactact ttcaaaagca tgactggccc agcaatcaag cccaatacta gggcaggaag
     6301 catggctagg aagctgccaa gataaggaac caaatttaaa ataccagcag taacacctag
     6361 cgtaaccgca tagcgtagac cgataatctt gaagaaaatc ataaacatta ctgctacaat
     6421 aatagctact gtcacttgcc ctcgaacata gttggacaac tgttgattca catctgacaa
     6481 aacctgtcct acaggttctt tcaattttgt cggcatgaat tgggtcaaat agttacgcaa
     6541 gccttttcca tcacgcaaga gataaaagag catgaaagga acaataatca aggcaacaat
     6601 cacttgagaa gccccgctaa taaaggcact cacccagttg actgcctgag atgaaacctt
     6661 actcgcccaa actgtagcct gacttgagaa gtttgtcaaa acttgttcta actgaggtct
     6721 gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta tatcttctaa
     6781 gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg gaatggcgac
     6841 tgccaagccc caaatgataa agagagctat gatgacaaag acaatgctga tggctatgac
     6901 gcgattgact ttgtgttttt ccatccaatc aacaatagga ttcaacaaat aatataacaa
     6961 accagacaga atgactggca acatcacaac tgctaaaaag tctaaaacag gtgaaaatag
     7021 aaaactaatc ttacttaaaa taaaaagatt gagtcccaat aataaggtta ccaaaaatac
     7081 cgtaatggcc ttgttatcca aaaaccactt gaaaaaccaa gataggctaa aatgtttctc
     7141 tttttgctcc ataaatactt cctttctatt gttctcccat tataccattt ttgaaacaaa
     7201 ataactcttt tttaaagtgc ttacatctaa ttggatgtct ttaattggct tgtttttgtg
     7261 atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt tattttggaa
     7321 cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca gaaactggtc
     7381 agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt gcctttgacc
     7441 agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt gcagcctatc
     7501 aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac tgttatgttg
     7561 ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga caggtccttg
     7621 tttataaacg ccaggaagat ggtagtcttc tacttagcga tatggatcaa cacagtggcc
     7681 aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta acacctgacc
     7741 actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac ctcgatcaag
     7801 aaggaaaatt atctaagctc tatacctatc acagcaagac aggagcaggc tcacgccata
     7861 tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat agtactatcg
     7921 aagttttaat ctacgatggc gttggcgaat ttgaacgtat gcaggtcatt tcaactttac
     7981 cagaagctta cgaaggcttt aatggaaccg ctgctattcg tctctctaca gacggtcaat
     8041 acctctacgc ttctaaccgt ggtcataatt ctatcgcagt atataccatc cttgcggacg
     8101 gtagcttaga gttattagaa atcgttccaa cacatggtca gactccacgt gattttgatt
     8161 tgacacccga ccaaaaattt ctcattgctg tccaccaaga ctctgacaat gcaactgtct
     8221 ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc catgttcccg
     8281 aagcggtctg tatccgtttt gctccttaag aaaacataaa aaatgaactt ggaattttca
     8341 agttcatttt tttcttatag tctatttccg acattgatac ggttaatggc acgttgcagt
     8401 gcaatcttcg cacgacgttc ttggtcaatc aagtgtttgt cttgtgcttc ttcaattgca
     8461 cgttctgcac gaagtttggc acgttctgca cgactgatat cgatatcacg agcacgttct
     8521 gcagagtcag cgacgattgt aatcatatca ttggcaattt caataacacc gccgtttact
     8581 gcaatccagt tcacgtgatc ttcgtcatca atacgtttta cctttacttc atcaactgct
     8641 aaaaccgcaa tcatattttc atgtcgtggc aagatcccca tctcaccatc cagagttcga
     8701 accgatacat agctggcatg gtgatcatag acgaggccat ctggtgtcac gatctggaca
     8761 gttaactgag ccatagatca cctcttaaaa tcccattttt tcagcttttg caatcacatc
     8821 ttcgatagaa cctacaccac ggaaggcatc ttctggcaag tggtcgtatt taccatcaag
     8881 gatttcctta aagccacgta cagtttcagc aactggaaca taagaacctg gctgaccagt
     8941 aaattgttct gcgacgttga agttttgtga caagaagaac tggatacgac gggcgcgagc
     9001 aaccaagatc ttttcttcat cagaaagctc atccatacca aggatagcaa tgatatcttg
     9061 caattcatgg taacgttgaa ggacacgttt tacttcagca gcaactgcat agtgctcttc
     9121 tccaacgatt tcaggtgcca aggcacgtga gcttgaagca agtgggtcaa cggctgggta
     9181 gatacccaat tgtaccaact tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc
     9241 tgttgctggc gctgggtcag tatagtcatc cgctggcaca tagatagcct ggatagaggt
     9301 tacagaaccc ttcttggttg atgtgatacg ttcttgcaat tgacccattt ccgtagcaag
     9361 tgttggttgg taaccaacgg ctgatggcat acgacccaaa agggcagata cttctgaacc
     9421 agcctgagtg aaacggaaga tattatcgat aaagagaagc acgtcttggc cttccacatc
     9481 acggaagtat tcagcgattg tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg
     9541 ctcattcatc tgaccaaaga ccatggctgt tttctcgata acgcctgatt ctttcatttc
     9601 ccagtaaagg tcattcccct cacgagtacg ttccccaaca ccagcaaata ctgaaatacc
     9661 accgtgctct tgggcaatgt tgtgaatcaa ttcttggatt aagacggttt taccaactcc
     9721 ggcaccaccg aaaagtccaa ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac
     9781 cttgatccct gtttcaagga tttcagaaga ggtagacaac tcatcaaaag ttggagcttt
     9841 tttatgaatt ggctgacgct ctgcgtcttc tgtaaaagga gcttccaagt caatggtatc
     9901 tcccaaaacg ttgaagacac gtcccaaagt ttctttacct actggtacag agattggacg
     9961 acctgtgtcc aatacttcca ttccacgagt caacccatct gttgattcca tggcgatagt
    10021 acgaaccata ccatctccta actccaaggc tacttcaagg acgatttttg tttttctttc
    10081 gtcatttttg tagacgacaa gtgcattatt aatctcagga agtttttccc ctgctgcaaa
    10141 caaaacgtct acaacgggac ccataacctg agcaatttta cctgaactca tctccttctc
    10201 ctattctata taagatactg tcggttccta gctcaactag gtcctaagtt cattttcata
    10261 cgagatggac tagagcctat tctaaggcac tagcacctgc tacgatttct gtaatttctt
    10321 gtgtaatcgc cgcctgtctg gcacggttat actgaattgt caaatcattg atgactttct
    10381 tagcattatc tgtcgctgtt tgcatggctg tcatacccgc agcattctca gctgtcttgg
    10441 catcgataat ggcaccgtaa atcatacttt ctgcaaactg aggcaacaac tgctccagaa
    10501 tttcttctcg gctggtttcc aattcaaaag tcaagctgta ctcttcatcc gcttcatttg
    10561 gatccaagtc aacaatcgga agcatttgtt ccacacgcat ttgactggtt agcgtattga
    10621 catggtggtt gtagcaaaca taaagctcat caaagagttc attttggtac atttcaacag
    10681 tttttgaaat aatcttacga acttgatcaa agctaggttg gtctgacaag ccacgtaatt
    10741 cataaagtgg ttgaataccg cgagccttaa agaaatcagc tcccatccca ccgatacaga
    10801 tcatttcaaa acctttaccg tctgggtggt attcttcttt caactccata acagctttca
    10861 aaatagagga attataacct ccaaccaaac cgcggtctga agtgataacg atatagcctg
    10921 tcttcttcac agaacggcta atcaacatcg gattagttga agcaccagct ccattaccat
    10981 gaaggatatc tgtcaaaagt ttacgcactt tctgagcgta aacttggaag ttgcgagcag
    11041 cttcttcaga acgacctagc ttagcagccg ataccatttg catggcatta gtgatttgac
    11101 tcgtattttt tgttgaggcg atttttgttt taatatcatt tagagatact gccatctgac
    11161 acctctattc ttattggaag ctagattgat tgagaaactc tgtaatcgca gcatccaaga
    11221 ctgcttcttc tggcaagtct tttgtatcac gaatggtttc caaaatctct ggatgttgag
    11281 catcaaagaa ggcatggaac tcttcctcga aacgaacaat atcatctact ggaacagtat
    11341 ccaagaaacc atgtgtcaaa gcataaagaa tggttacttg tttctcaaca ggtaatggtt
    11401 tgtgaacagg ttgtttcaag acctcaacgg tacgacgtcc acggttcaac ttagcctgtg
    11461 ttgctgcgtc caagtcagaa ccaaacttag taaaggcttc caactcacgg tatgaagcaa
    11521 ggtcgatacg aagtgtacca gcaaccttct tcatggcttt gatttgtgca gaaccaccta
    11581 cacgagatac agatgaaccc gcatcgatgg ctggacgaat acctgcattg aaaaggccat
    11641 cgccaaggaa gatttgtcca tcagtgatag aaatcacgtt ggttgcgata taggctgaga
    11701 tatctcctgc ttgtgtctcg ataaatggta gggctgtaat tgatccacca ccaagttcat
    11761 cagaaacttt agctgagcgc tcaagcaaac ggctgtggag atagaaaaca tcccctggga
    11821 aggcttcacg acctggagga cgacgaagca agagcgacag ttcacgataa gctaccgctt
    11881 gttttgatag atcatcgtat acaatcaaaa catgcttacc ttgatacata aattcttccg
    11941 ccatagcaac cccagcataa ggagctagga agagcaatgg agatggttgt gaagcagagg
    12001 ctgtcacaac gattgtgtag tccaaggcac cgtactgacg aagtgtttct acttgcgtac
    12061 gaactgttga ttctttttgt ccaatcgcga cgtagataca gatcatatct tgatcttttt
    12121 ggttcaagat tgtatcaatc gcaatggttg ttttccctgt ctgacggtca ccgataatca
    12181 actcacgttg accacgacca atcggtacaa gggcgtcaat agctttcaaa ccagtttgca
    12241 atggttctga aacagactta cgttgcataa caccaggagc tggtgcttct actggacgag
    12301 ttttatcagt gtggatttct ccaagaccgt caactggacg accaagcgga tccacaacac
    12361 gaccaatcag actttcacct acagggactt ccatgatttt ccctgtacgg cggattgtat
    12421 cgccttcacg gatatctgta aagtcaccta ggatgataat accaacgtct gttgactcca
    12481 agttttgagc cataccataa gagccgtttt caaaattcaa caactctcca ctcatggcat
    12541 tttcaaggcc gtgagcacgc gcgataccat ccccgatata ggttacaaca cctgtttcag
    12601 tcacatcaaa attgggtttg aaattttcaa tttgttgctt aattaaagcg ctgatttctt
    12661 gtgcgttaat tgccaaaaga acaccacttt ctatttcaaa ttttctttaa caactttaag
    12721 ttgttgttta atactcacat caattgtctt gtgattggca aaaatgacaa aaccaccaat
    12781 gagactttca tcgatttgtt cttttacact ccttactttc agagacattt ttttctcaat
    12841 caaagggagc aaacgagtct tctgttcatc agttagagga taagcagacg taatcgtcac
    12901 ttcaaatcga tttgtttctt tttcaagtcg gttcaagcaa tctacaagca catcataaaa
    12961 aagatttgct ctgtgattgt aggccagaac ctggataaag ttttgtaata aaggtgacac
    13021 agaatcttgg aaaaaagcaa ttgttttttc cttatccgac tcgtctactg ccacttgttt
    13081 taaaaaagaa ggcagacctg ttttttcaac aacttgcttg atttgagtca agtctgaaaa
    13141 gatacggtct tcttctcctt tttcaagtac caattggaca aaaggcatgc tgtatttttc
    13201 aattaccttt actgttttct tgtccattaa gcttctccta gctgatcgat atactgatca
    13261 atgagtgctt tatgggcatg actgtcaagg ttttgtgaga tgattttacc agctaagctg
    13321 atggtcaaat ctgcgacctc acccttaaca ctctgtaaag cttctacttt attttgagca
    13381 atttcttgat tggctttttc ttttaagtgt cctgcttcta gtttagcatc tgctaagata
    13441 ttagccttac tttgctcagc tgtttccttt gcattttcaa tgattgtctt agcttcttta
    13501 cggctaccag ctaattcatc ttcgcgtttt tgagccaata cttctgcttt ttgacgggct
    13561 tcttcagctc tgtcaatatc tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta
    13621 atattagacc atgcaaattt tttaatcaag actagcaaaa gaataaaaga gccagtaatt
    13681 aaaacaaaat taccaattaa ttcacctact gttacgtgca tcagttactc ctttctattc
    13741 ctcttcaata ttaatcttat tccctaaata cacagatgtc aaaagagtaa aaacataagc
    13801 ttggatgcag gaaataaaga cagaaaatgc agtccaagcc aaattagctc caaaggctac
    13861 tggataccaa taaatagctt ggtgggaaag aagaagtaac aaactcgtca tgacctctcc
    13921 tgcaaagata ttcccaaaaa tccgcaaagc caaagataag aagtttgtaa attcttccaa
    13981 gatattcatc ggtatgacaa aaacaggact cataaaagat tttatacttt ttttaaatcc
    14041 acgacgacga acgctttcta tatgtgtcaa caaaatgaca agaaaagata aggttaagtc
    14101 atactgtaaa ttagcggttg gcgaactcca ccagttagtc ccatcgatcg tttgaagctt
    14161 tgtcattaag ccaaggttat tggcaatcac catgaaaagg aataaacaaa ggaaaaagag
    14221 tgagtaatct ttcatgtagc gcgaaccaat gttaggttct gtaaatccaa taacaaaatc
    14281 atagacatac tcaagtacat tttgctttcc tttgggtttc aaggtcatat tgcggcttgc
    14341 ccaataaata aagacaaaaa taactcccac aatcaacaaa gtcatggcta acatagtcag
    14401 attgaagata acaggaccaa tagagatgat tggattaata ctttcttcca tctaaaatcc
    14461 tcccttttct tctcgttcca tgtatttatt tgataataaa tgagaagaca agagttacaa
    14521 agaaagttcc ttcaataaag gcaacaccta aaaacatcaa actacgaaac tcagaaagca
    14581 tatctggttg gcgtgctact gatttaaaca gtccattcat caataaacct tcaccgacag
    14641 atacgcccat acaggcaata cataagccta aaaatgttaa attcataaca aattctcctt
    14701 taaaataaaa tttacttact tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg
    14761 ctattggaag cgtttaataa aaattatttc cattttgcta aatttcaagt tcaagttagc
    14821 catccagaag tcttctctgg gtgacttgta gtccaagcat tttttaggat agttgttaat
    14881 ccacttttcg atgaatgcga cttctttggg agtcattttc ttggttccct taggtaacca
    14941 tctacgaatg aacctgttgt gattctcatt agttcccctt tcccaagagg cataggggtg
    15001 cgcataataa atgtgctcct cagaaaatac atcagacaag cgattgaatt ccgttccatt
    15061 atctgccgtg atggaaagaa tcttgtgttg ttttaagatg agttttagag cctgattgac
    15121 cacctcagca cttttatttg gaatcaatcg gatgatctga tgtctactct ttcgatccgt
    15181 caagacaagc aagcagtagt ttttcgatct cgtaagtaga accgtatcaa tctcataatg
    15241 cccattctcc aagcgaagat tgatagcttc aggccgctgt gcgatggatt gaccagcagg
    15301 tttaaagttg gtgctagcct gtttcttaag cgcttttcct tttctagggt aaagcagatc
    15361 ctgcttgctt aaccccaatt ttccacgatg aatccaatag taaatggttg aaattcctac
    15421 gttaacccct ttagccatca ccatcatttc aggcgaaaat ttttggttat gatagtggag
    15481 aatcttttcc tttagttcct tggtcaagct tgatttcttg accgagcgct tgcgattgtt
    15541 ttcataagac tgttgagcat agtcggcaga ataaacctct ttgaagcacc cttttccaag
    15601 acattgtcgg actgtcccac gcttgatttc agtgtggata gtttgaggag cttttccaag
    15661 tagagaggca atttctctat ttgatttccc ttcttttttc catcgttcta ttaagcaacg
    15721 gctatcgatt gtcaaatgtt tgccttttgt agtataatag ttttgcatct ctgtgccttt
    15781 cttgtgtttg tggttgaaca acaagtatag cacagaggtg ttttcttatg cctacaagag
    15841 ctttcattat ttccactttc tttcggattt cactctattc tgaaaaactt gtgtatattt
    15901 actgaagcta gcaagtctta cctgtaaatt taatgaaagc aacacaaaat ccgagagggg
    15961 aatctcggat taatgtcaat ttaaaaagat agagagtttt tagtttaaat aaattgtttt
    16021 aaaatatcaa caacatcact tcttttctta acctgataag ccttaattcc taattttggg
    16081 gctacgatta tattgtcctc aatatcgtct agaaagacac aatttctagg ttataactgg
    16141 tatttatcaa tagttattca tatatatcag tccacctcca tactcacctt acagattctt
    16201 ttggtaataa tatctttgcc taatttagag atagtcttgc aaagaaaaaa cttccttgta
    16261 gccatgtttc tgataaaagt ccggtgcctg aaactggtaa gtattgacaa aggcaaaaca
    16321 acaatttcga ttcttagctt cactttctgc ctgttgcaat agttttgaac cgattccttg
    16381 ccctcgcagt tcctctttta caaacaaata ctcgatttct agccaatttc caaaagtctc
    16441 tgctatcaaa cctgccagga gattgccctt ttcatcttcg acataaagat taagtggctc
    16501 actttcagtc tcttctcttt ttgaacggtt ataaacacga agcagattcc ctatttcttg
    16561 cgatttatgt gattccttat tttccaatct aaagtatagt gaaatgaaat aaaacatgcg
    16621 caaatcgatt aaggaattta atctaatttc taacaatgtc ttagaaatca aagtgtacta
    16681 tgttaacttc aatgcactat acatctaata ctcaataaaa atcaaataat actcaataaa
    16741 aatcaaagag
//
LOCUS       DAVDHZ010000046        16405 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000046 DAVDHZ010000000
VERSION     DAVDHZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.047"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            57..344
                     /locus_tag="VUR46_001812"
     CDS             57..344
                     /locus_tag="VUR46_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457182.1"
                     /translation="MRLFKKQTHNQDSFKRLIHRLSGMSETDLHKVNQLLDVVFDATS
                     QTIHEETMTPKDMPKEPILDETITEAKNKLNTEQLEKRIEQFRQAKKPKSG"
     gene            413..889
                     /locus_tag="VUR46_001813"
     CDS             413..889
                     /locus_tag="VUR46_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5457183.1"
                     /translation="MIGENIKSLRRTHDLTQPEFAKIVGISRNSLSRYENGTSSVSTE
                     LIDRICQKFNVSYVDIVGEEKMLTPVEDYQLTLKIEVIKERGAAVLSQLYRYQDSQGI
                     AFDDETNPWILMSDDLSDLINTKIYLVDTFDEVERYNGYLDGIERMLELARHQVVA"
     gene            889..1671
                     /locus_tag="VUR46_001814"
     CDS             889..1671
                     /locus_tag="VUR46_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET5457184.1"
                     /translation="MALEAFRQDDFDLALKRTIRSLTRGKTVSTSPQAILLGGQSGAG
                     KTTIHRIKQKEFQGNIIIIDGDSYRSLHPNYLVLQEEYGKDSVDYTKFFAGKMVEHLV
                     DELSKDGYHLLIEGTLRTTEVPRKTAQLLKSRDYQVSLALIATKPELSYLSTLIRYEE
                     VYAENPSQARATSKEHHDGIVEHLVDNLRELETDKLFDQIQIYQRDKRCVYDSDTDDG
                     SVADVLQDCLFGKWSKVEEEMIKEAKEYLKRLSKSNNENILV"
     gene            1868..2431
                     /locus_tag="VUR46_001815"
     CDS             1868..2431
                     /locus_tag="VUR46_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457185.1"
                     /translation="MTESQNIGNFSNNNVQNMYVTNIEQRTLIPTVIFQLLKYVEGFH
                     SQNDEKFLLEQPAELKEKLQFNNSRRYIRLFKEGLSNYISLEKVLKDEFTDSQRVVEN
                     IKNIFMDHTPIDAEGNPIVGNGDECLKKMHDDIKERIARDPNFLSSQIDDLELDKFII
                     ALLQYGVIECQILLNPNNYMECNDVIT"
     gene            2418..2651
                     /locus_tag="VUR46_001816"
     CDS             2418..2651
                     /locus_tag="VUR46_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457186.1"
                     /translation="MLLLDKNAEPKKTIFYLSAIVHGLILKRIVNIENLYIELQKEIE
                     DELNYDFFILALDFLFLLDKIRVNNEGDIESVH"
     gene            2641..4359
                     /locus_tag="VUR46_001817"
     CDS             2641..4359
                     /locus_tag="VUR46_001817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HET5457187.1"
                     /translation="MFIKSLSIISKNTDVVLRKIEFKNGINFIVDSEKSYKHNKVGKT
                     TCLKLLDLSLGAKSKDAIFKDYETQSVNEQLRLFIENQKIYTDMVLIDDFNHPSKEVS
                     IKTELFNRGKRYINGEQTSYDEVNKYLNELLFENRSQKPSFRSAIKSFVRILMTKDNT
                     QFLKVLDNFSNISEYRAVYNYLFDISDLENDLEFGKLKQELKNIKSKENNYKKVNTVD
                     DVVKIKQINVAIEKEIDRLEKEINDLVDKKAFEKNRIHINDIRKKYEEISRQLSKIDF
                     DILQLQKYIKEAEEKSQRIVNQELANDFFQEISELLPSITKTFMDLVEFNSQLSRNKL
                     SYFNDRMQELIMEKEDKENLLTKLTEENSEFISLVEENKVDLYYDKLNQLDELKIKKV
                     KNESTITSLGNIEEQKNTLEKRLSKLEMIVKNNEAEYQKKMDIFNSYFKSVADRINKE
                     QPVLLYNPKTDEFPVSIGQLSEGTSTGTRKSLIAAYDIAYQLFAREINKATPKFIVHD
                     VLESIEGDDIRALVDEVESNQIQYISAILKEKLVSSGMSTEKQNEIIVLQLSMKDRLF
                     ERGNNC"
     gene            4693..5055
                     /locus_tag="VUR46_001818"
     CDS             4693..5055
                     /locus_tag="VUR46_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457188.1"
                     /translation="MRQDIKLIRKQFRITRQEDNQIKEMMREQQLESFSEFLRQNLLK
                     KESHEDVLIRWFTLWQSQKIEQISRDILQVTTLAEQSHQVTAEHLRIILTCVQELIAE
                     VNQASPLSQDFRDKYMGG"
     gene            5058..5423
                     /gene="mobC"
                     /locus_tag="VUR46_001819"
     CDS             5058..5423
                     /gene="mobC"
                     /locus_tag="VUR46_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET5457189.1"
                     /translation="MENRYRTNLKKVFLTDQELAVLHDRIGQSRCKNFSAYARKVLLN
                     PNMTFLTIDTSNYEDLVFELRRIGNNINQIARTVNQNHILTPSDRELLVQGICQLIKE
                     VEKDFNIKCQQLKEFYGSH"
     gene            5410..7296
                     /locus_tag="VUR46_001820"
     CDS             5410..7296
                     /locus_tag="VUR46_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET5457190.1"
                     /translation="MVVTKHFAVHSTKYRKSLIKYILNPEKTEQLKLISDFGMRNYLV
                     FPSYEEMVEMYEANLTNNDRLYDSRNDRQQIKQTKIHAHHLIQSFSPEDKLTPEEINR
                     IGYETIKELTGGNFRFIVTTHTDRNHVHNHILINSVDLNSDKKLKWDYVQERNLRMIS
                     DRLAKEAGATIIQPNRYSHEKFETYRKTNHKFELKQRLYFLLEHSNNFEEFLAKAPAI
                     NVEMDFSHKHARFLMTDREMKQVIRGKQLDKRQPYTEDYFREQFATRAIEQRLDFILP
                     RARDLSHLLEMAEQLNLTISPKKKHVTFTLTEKGRTISIENKKISTKHLYDVQFFEDY
                     FDQRESLTDPDLTNLVSDFEIYQEEQDKDKLPSEELLAAYKEFKEKRDQIQEFEVVLA
                     DHQIDKVVKDGLFIKMNYGVKKDGLVFIPNRNLDIHENEQGKSHHVFIRETAQFFIYN
                     KDSVDLNRYMRGRELICQLTHDSKHIPKRRRPTIASLKEKISEVNLLIELDINNQSYQ
                     EVKDELIKDIAQLDLTITNLQDKVAHLNKVAEILLNLNNSDPENRRLARYDYVKMNLT
                     AAINFEQVEQEISRSQQSLKDLIDKYEFKVRRLEKFVKNISSIYDYPFGGKTYTNNYQ
                     PDFE"
     gene            7703..7963
                     /locus_tag="VUR46_001821"
     CDS             7703..7963
                     /locus_tag="VUR46_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HET5457191.1"
                     /translation="MDNNFMSFPDRIGTNSSKWRIFETNPNMVSSSLADMDFEIPEFI
                     RSVFIDYMALDFMGYSYQSEKALEAILNWEKKNMGTILIKKN"
     gene            7918..8295
                     /locus_tag="VUR46_001822"
     CDS             7918..8295
                     /locus_tag="VUR46_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET5457192.1"
                     /translation="MGKKEHGYYFDKEKLILLDSVMTGVANAIQAFTNLGDAVLINDP
                     VYPSFKQIIENNGRKPVFSELEIKDGVYRFNFEKFEDCIITNKVKVFVLCNPHNPLGR
                     AWEIAELNKIGNICLKYNPDFIT"
     gene            8415..8684
                     /locus_tag="VUR46_001823"
     CDS             8415..8684
                     /locus_tag="VUR46_001823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457193.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVRQRILKKYGWMVLDNL
                     IEDKVLETAISEGFFYVKEYNRGKKIVIRCLLCFTKKISIITVVK"
     gene            8642..9625
                     /locus_tag="VUR46_001824"
                     /pseudo
     CDS             8642..9625
                     /locus_tag="VUR46_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9615..10727)
                     /locus_tag="VUR46_001825"
                     /pseudo
     CDS             complement(9615..10727)
                     /locus_tag="VUR46_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            10989..11186
                     /locus_tag="VUR46_001826"
     CDS             10989..11186
                     /locus_tag="VUR46_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5457194.1"
                     /translation="MYIRVKNLREDSDYNQSQIAQYLNCSQSTYSRIESGIQDIPTQF
                     LKKLAKLYGVTTDFLLEMDKE"
     gene            11457..11597
                     /locus_tag="VUR46_001827"
     CDS             11457..11597
                     /locus_tag="VUR46_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457195.1"
                     /translation="MEKTQTGADLPQVVIEGYKVTVRVTDKPLSLTDVLDDLLGRQLE
                     KI"
     gene            11697..13265
                     /locus_tag="VUR46_001828"
     CDS             11697..13265
                     /locus_tag="VUR46_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET5457196.1"
                     /translation="MTRACTYLRLSRDDGDNVESNSIINQRSLLRDYARRHDFTILEE
                     FVDDGISGLTFNRPDFNRMMVMVNNKTIDTIIVKDLSRFGRDYIETGKYLQRIFPAMG
                     IRFISVNDHYDSLTADTNETHLVMPIKSLINDSYCRDISTKVRSTQKAKRQKGEFIGA
                     FAPYGYRKDHNQRNHLVVDEAVRSTIETIFALKLEGYSSNAIANFLNQAGVETPLQRK
                     RACQERIKGFYGYRHKWDTKMVNRILTNRVYTGTLEQGKQTKLNYKSQKSVAVNPEDW
                     VRVEDTHEAIISTSTFSIANNLLLRDVKHGKNTPDLFAGLLFCGDCQAQLLQRKLRYK
                     DKETVQYICSTYNNGQGCSRHAIKEDVLTDLVSTIVHQHLDWKSYLVKSIPDYLDQEH
                     FLEVDFTSLISERQKYEQLLQSLYLDLDDGLINETEYQEFQRSYRQKLKQIEDTIVQK
                     KELAQTLYDKLQDKETWLEQLSTIQHEQELNRLTLVTLLDRIIVHEQQALTLMFHDVA
                     ELSLLQQFSNMEVV"
     gene            13265..14881
                     /locus_tag="VUR46_001829"
     CDS             13265..14881
                     /locus_tag="VUR46_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET5457197.1"
                     /translation="MARTKNRSRVETVEKIPLQTYRTGIYIRLSKERTESWRHKSQSL
                     KTQESLARTFAQEKGLTVTKCYIDYEYSGTKFNRPAYQDMMEDIKRGVINCILIRDLS
                     RLGRNYIEIGRLIDKVFPFMGVRFISINDNLDTLNGLEDKKSFEVEIKNLVNDLYSKD
                     ISKKVMSYNIHQASQGYYIGTSAPYGYRIDRQEAGARLVIDNQVKPILEFIFQQAIEG
                     VSISQITTELNHRGIAVPQSYRGTGQLYRSEQDIKRWHAGNLLRLIKMPVYRGVLIQR
                     TRNKSLSEEDYIHFENAQEAYVSKDNYEKILFYLDSRKSVKKTSIVRTPNRYRGLVYA
                     KTKSTQMVRRCRHFSNNKSDYDYYYFTDYIYDSETTERKTVYISENALDKIIVELIQS
                     EMKRLGTVETLLPRLETKKDDCLKTYHKQITCHQWTITQLQAELSDLYASFSLNRSER
                     EVYLSQKNEIIAKIETISQEIALCETSIKQIEEEHSKQVNWVRHLAKSQNQVVLTAEL
                     LNALIERIEVDVDKTVTVTFSCQIGGGEHD"
     gene            14874..16313
                     /locus_tag="VUR46_001830"
     CDS             14874..16313
                     /locus_tag="VUR46_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET5457198.1"
                     /translation="MTKIALYLRLSVDEADTDESNSITNQRYLLNNYLDQTPEFKNWE
                     RLEFVDDGFSGTSLKRPAFQRMMADVKAGTIRHIIVKDLSRFMRDYLELGNYLENIFP
                     FLGVRFIALNDHYDSLVSEHNGLDIDVPFRNLLNDFYAKDVSEKVKSAMNSMKRSGKN
                     MSWLPPFGYIKDPNDRFKIIIDEEVAPIVRRIFRLCIEGMGTQKIAMLLNSEQTITPA
                     ERKMQVSQARYTKSIIITAEQKRNVWTRSGILQILKNEAYKGTYLFNTRTTVNGKQIR
                     RPESEWERLDNNHEAIVSSEDFDKAQQSLTSRISGTKSQVCNQPEEVLLRGLVICEHC
                     GHRLLRYSHNNNNNYFYCCYCRSQGQNMKSCRIDRIEEAIEKELKSRLPMNSPKLSKT
                     NLIREVERLKTQKVSHFQDYKEGLMTRETYMEKRQNLDNSIMEIEEQLKVVGRENIAF
                     DKKLTREVVDTHIERIVVNGQGSFTVVYK"
BASE COUNT         5656 a         2763 c         3247 g         4739 t
ORIGIN      
        1 atgacttgta agtacgagca gtccttatgt gggctgcttt ttacgagggg gaacagatga
       61 ggttattcaa aaaacaaacg cacaatcaag atagttttaa gcgactcatt catcgcttat
      121 caggaatgtc tgagactgac ttacacaaag ttaaccaatt attagatgtc gtttttgatg
      181 ctacaagtca aactatccat gaagaaacaa tgactcctaa agatatgcca aaggagccta
      241 tattagatga gactattact gaagctaaga ataaactgaa tactgagcaa ctggaaaaac
      301 ggatagaaca gtttagacag gcgaagaaac cgaaaagcgg ataatgcacc aaaaatggtg
      361 cgttatccat tttttgtgct ataatgaaag taacgaatag gaggtcttat ctatgattgg
      421 agagaatatc aaatcattac gcagaacaca cgatttgaca caaccagagt ttgccaaaat
      481 tgttggtatt tcaagaaata gcttgagccg ttacgaaaat gggacaagct ctgtttcgac
      541 agaactcatt gatcgaattt gccaaaaatt caacgtgtca tatgtcgata ttgtaggaga
      601 agaaaagatg ttaacaccag tagaagatta tcaattgacg ctgaaaatag aagtcatcaa
      661 agagcgtgga gcagcggttt tatctcaact gtatcgctat caagatagtc aagggattgc
      721 ttttgatgat gagactaatc cttggatttt gatgagtgat gacttgtctg accttatcaa
      781 taccaagatt tatctggtcg atacctttga tgaggtagaa cgctacaatg gttatttgga
      841 tggcattgag cgtatgttgg aacttgctcg tcatcaggtg gtggcttaat ggcattagaa
      901 gcatttcgtc aagatgactt tgacctagcc ctgaaacgca ccatccgttc tttaacccga
      961 ggcaagacgg tttcgactag cccacaagct attttacttg ggggacaaag cggagcaggt
     1021 aagacgacca tacaccggat taaacaaaag gaatttcaag gcaatatcat cattattgat
     1081 ggcgatagct accgctcttt acacccgaat tatcttgtct tacaagaaga atatggtaaa
     1141 gatagtgtgg attacaccaa attctttgca ggaaaaatgg tagagcacct cgttgatgaa
     1201 ctcagcaaag acggttatca tttgttaatt gaaggaacct tgagaacgac agaggttcca
     1261 agaaaaacag ctcagctatt gaaatcaaga gattatcaag tatcactcgc attgattgcg
     1321 actaagcctg aattgtccta tctcagcacc ttaattcgct acgaggaagt ctatgccgag
     1381 aatccaagcc aagctagagc aacttctaaa gagcatcacg atggtattgt agaacatttg
     1441 gttgataatc taagagagtt agaaactgat aaactctttg atcagattca aatttatcaa
     1501 cgagacaaac gctgtgtcta tgattctgat acagacgatg gttcagttgc tgatgtgttg
     1561 caagattgtc tcttcggaaa atggagtaag gttgaggagg agatgattaa ggaagctaaa
     1621 gaatatttaa aacgattgag taaaagtaat aatgaaaata tcttagtatg aaatagaggt
     1681 agaaaatagt ggaaacagta aacacaattt taggaatagt aggatctata tttggcataa
     1741 ttgctacagc aatttcttta aaaaaccaga acgatattaa aaaaattata aagaattcca
     1801 ataatagcca aaatataggt aacaatagca gtaataatgt acagaatatt ggtgatggga
     1861 gataaaaatg actgaatccc aaaatatcgg aaattttagt aataataatg ttcaaaatat
     1921 gtatgtaaca aatattgagc agcgtacatt gatcccaact gttatttttc aacttttaaa
     1981 atatgttgaa ggatttcact ctcaaaacga tgaaaagttt ttacttgaac aaccagctga
     2041 attaaaggaa aaactacaat ttaataattc taggagatat attagattat ttaaagaggg
     2101 tctcagtaac tatatttcac tagaaaaggt attaaaagat gaattcacag atagtcaaag
     2161 agtagttgaa aatataaaga atatttttat ggatcatact cctatagatg cagaaggaaa
     2221 tccgatagta ggtaatggtg atgaatgttt gaaaaagatg catgatgaca taaaagaaag
     2281 aatcgcgaga gatcctaatt ttttatctag tcaaattgat gacctagaat tggataaatt
     2341 tattattgca cttcttcaat atggagttat agagtgtcaa atattattga atccaaataa
     2401 ttatatggag tgtaatgatg ttattacttg ataaaaatgc tgagcctaaa aagactattt
     2461 tttatctctc agctattgta catggcttga ttttaaagag gatagtcaat atagaaaatc
     2521 tttatataga gcttcaaaaa gaaattgaag atgaactaaa ttatgatttt tttatattag
     2581 cactagattt tctttttcta ttagataaaa taagagttaa taatgaagga gatattgaga
     2641 gtgttcatta aaagtttgag tattatcagt aaaaatactg atgttgtatt gagaaaaata
     2701 gaatttaaaa atggaattaa tttcatagta gattcggaga agtcttataa gcataataaa
     2761 gttggaaaaa caacatgctt aaaattactg gatttaagtt taggggcaaa aagcaaagat
     2821 gccattttta aagattatga aacacagagt gttaatgaac aattaagatt gttcattgaa
     2881 aatcaaaaaa tctatactga tatggtgtta atagatgatt tcaaccatcc ttctaaagaa
     2941 gtttctataa agacagaatt gtttaacaga ggtaaacggt atattaatgg agagcaaact
     3001 tcatatgatg aagttaacaa atatttaaat gaattattgt ttgaaaaccg ctctcaaaag
     3061 ccaagtttta gaagtgcgat aaagtcattt gtacggattt taatgactaa ggataatact
     3121 caatttttaa aagtattaga taatttttca aatatttcgg aatatcgcgc tgtatataat
     3181 tatttgttcg atatttcaga tcttgaaaat gatttagagt ttggtaaatt aaaacaggaa
     3241 ttaaaaaata taaaaagtaa ggaaaataat tataaaaaag taaatactgt agatgatgta
     3301 gtaaaaataa aacaaatcaa tgttgcaatt gagaaagaaa ttgaccggtt agaaaaagaa
     3361 ataaatgatt tagtagataa aaaagcattt gagaaaaata gaattcatat caacgatatt
     3421 agaaaaaaat acgaggagat aagtcgacaa ttaagtaaaa ttgattttga cattttacag
     3481 ttacaaaaat atatcaaaga ggctgaggag aaatcccaaa gaatagtaaa tcaagaactg
     3541 gcaaatgact tttttcaaga gatttccgaa ttgttaccta gtattactaa aacttttatg
     3601 gatttagttg aatttaattc ccaattgagt agaaataaat tgtcttattt taatgataga
     3661 atgcaagaat tgataatgga gaaggaagat aaagagaatt tattgacgaa attgaccgaa
     3721 gaaaattcag aatttatatc tttagttgaa gaaaacaaag tagatttata ttatgataag
     3781 ttaaatcaac tagatgagtt aaaaataaaa aaagtaaaaa atgaatcaac aattactagt
     3841 ttaggtaaca ttgaggagca aaaaaatact ttagaaaaaa gactttctaa actagagatg
     3901 attgttaaaa ataatgaagc agaatatcag aaaaaaatgg atatttttaa tagttatttt
     3961 aagagcgttg cagatcgaat aaataaagaa caacctgtct tgctttataa tcccaagaca
     4021 gatgaatttc cagtttcaat tggccaacta tctgaaggta caagtacagg gactagaaag
     4081 tcccttatcg ctgcatacga tattgcttat caactttttg ctagagaaat taataaagca
     4141 actcctaaat ttattgttca tgatgttctt gagagtattg aaggtgatga tattagggcg
     4201 ttagttgacg aagtggaaag caatcaaata caatatattt cagcaatctt aaaagaaaag
     4261 ttagtatcct ctggtatgtc aacagagaaa caaaatgaga taattgttct acaactttct
     4321 atgaaagata gattgtttga aagaggaaat aattgttaga taaaatataa gtcttgaatt
     4381 ttaaaaggaa gttcaagact tttttgtgat aacttttcca aatcatcctt gttatcctaa
     4441 tgtcattcct aagaaaatca aatcttgatt tttcactggg ggtttggggg cgaagccacc
     4501 atagtttctt atcgtcggct gacaaacctg taaggttttg gttggctgac gattagattt
     4561 tgggttattg tggacacaat aactgagctc gcaaaagccg aaaaagaacc ttttgaggct
     4621 tttaggaagt gtactgacag tgtgaggctg ccttacattg tcaggcaagt aattttttga
     4681 aaggataaaa ccatgagaca agatattaag ttaatcagaa aacaattcag gataacaaga
     4741 caggaggata atcagataaa agaaatgatg agagaacaac aattggagag tttctctgaa
     4801 ttccttcgcc aaaatttatt gaaaaaagag tctcacgaag acgttttgat tcgctggttt
     4861 actctctggc aatctcaaaa gattgaacaa atcagtcgag atattttaca ggtgactacc
     4921 ttggctgaac aaagccacca agttacggca gagcacctac ggattatctt gacctgcgta
     4981 caggagctaa tagcagaggt taaccaggct agtccactta gtcaagactt tcgggacaag
     5041 tacatgggag gttagggatg gaaaatcgtt accgcaccaa tcttaaaaaa gtttttctga
     5101 cagaccagga acttgcggtc ttgcacgacc gtatcggaca gagtcgctgt aaaaatttct
     5161 ctgcttatgc cagaaaagtt ttgcttaatc ctaacatgac cttcctaacc attgacacca
     5221 gcaactatga agacctggtt tttgaattga gacgaattgg aaataacatc aatcaaattg
     5281 cacgaacggt caatcagaac cacatcttaa caccaagtga ccgtgagttg ttggtacagg
     5341 gcatttgcca actcatcaag gaagttgaga aggacttcaa cataaagtgc cagcagctga
     5401 aggagtttta tggtagtcac taagcatttt gcggttcaca gcaccaagta ccgcaagagc
     5461 ctcatcaagt atattctcaa tcctgaaaag acggagcagt tgaagttgat ttctgatttt
     5521 ggcatgagga actatttggt ttttcctagt tatgaggaga tggtggagat gtatgaggcc
     5581 aacctcacta acaatgatag gctctacgat tctagaaacg accgccagca aatcaagcag
     5641 accaaaatcc atgcccacca cttgattcaa tctttttctc ctgaagacaa gctgacacca
     5701 gaggaaatca accgcattgg ctacgagacc atcaaggaac tgacaggtgg aaactttcgt
     5761 tttatcgtga cgacccacac tgatagaaac catgtgcata atcatatcct gataaactct
     5821 gttgatctta actctgacaa gaagctcaaa tgggattacg ttcaagagag aaaccttcgc
     5881 atgatttctg accgcttggc caaggaagca ggggcaacga ttatccagcc taaccgttat
     5941 tcgcacgaga agtttgagac ttaccgcaag accaatcata aatttgaact caagcaaagg
     6001 ctttattttc tcctggaaca cagcaacaac tttgaggaat ttttggccaa ggctcctgct
     6061 ataaacgtgg agatggattt ttcccacaag cacgcccgtt ttctcatgac cgaccgagag
     6121 atgaaacagg ttattcgcgg taagcaattg gacaagcgac agccctacac cgaggactat
     6181 ttcagagagc agtttgcgac acgagccatt gagcagcgat tggattttat tttgcctaga
     6241 gcccgtgacc tctctcatct tttggaaatg gcagagcagt taaacctgac aatctctcct
     6301 aagaaaaagc atgtgacttt tactttgacc gagaaaggtc gaaccatttc cattgaaaac
     6361 aaaaagatta gcactaaaca cttgtacgat gttcagttct ttgaggatta ttttgatcaa
     6421 agagaatccc taacagatcc tgacttaact aacctggtat cagactttga gatttatcaa
     6481 gaggaacagg acaaggacaa acttccaagt gaggaactcc tagcagccta caaggagttc
     6541 aaagagaaac gtgaccagat tcaggagttt gaagttgttc tagctgacca tcagattgat
     6601 aaggtggtca aggacggtct ttttattaag atgaattacg gtgtcaaaaa agacggcttg
     6661 gtattcatac caaaccgtaa tctagatatt cacgagaatg agcagggtaa gtcccaccat
     6721 gtctttatac gagagaccgc ccagtttttc atttataaca aagacagtgt agacctcaat
     6781 cgttacatga gagggcgtga actaatttgt caactcactc acgacagcaa acatatccct
     6841 aaacgtaggc gaccaactat tgctagcctc aaagagaaaa tctcagaggt taatcttctt
     6901 attgagttag acatcaacaa ccaatcctat caggaagtca aagacgagtt aatcaaagac
     6961 atcgcccagc tggatttgac cattacaaat ctgcaggata aggttgctca tcttaataag
     7021 gtcgcagaaa tcctgcttaa tctcaataac tccgatccag aaaatcgccg actggccaga
     7081 tatgattacg tcaagatgaa cctgactgcg gctataaatt ttgaacaagt tgaacaagag
     7141 atttctcgct cacaacaatc tttaaaagac ttgatagata aatatgaatt taaagttagg
     7201 agactggaaa aatttgttaa aaatattagt agtatttacg actacccctt tggaggtaaa
     7261 acatatacaa ataactatca acctgatttt gaataaacat ttgtctttta gatgatttgt
     7321 atacgatatt ttataaatga ttaccacttt ttatttttca agaatcaaaa taaccgtatt
     7381 aatgtatatt ttttatatag tacagtatta aataggttat ctgaagtgac acccaaaaat
     7441 tgttatataa agaaaaaggt actagatatg ctttttcata ttttaactta aataaaatgg
     7501 caaactaaaa ttgtaaaaat aatttagcga attaaagaat attgaactat aaattaaatc
     7561 agtgagatgt gtttactaaa tcaaaaaaat taaactaagg tatttcatat ttttagttaa
     7621 tctggtagac tttagtaagt tgtataatat ttaagtcaat ttttagagga ggctttaaaa
     7681 tgtaagagag gaagagagaa taatggataa taattttatg agctttccag ataggattgg
     7741 aactaattca agtaagtgga ggatttttga aacaaatcct aatatggttt catcttcttt
     7801 agcagatatg gattttgaaa ttcctgagtt cattagaagt gtttttattg attatatggc
     7861 attagatttt atgggctata gttatcaatc tgaaaaggct ttagaggcta ttttaaattg
     7921 ggaaaaaaag aacatgggta ctattttgat aaagaaaaac taattttgct ggatagtgtt
     7981 atgacaggag tagctaatgc aattcaggca ttcacaaatt tgggagatgc tgttttaata
     8041 aatgatccag tatacccttc ttttaagcaa ataattgaaa ataatggcag aaaacctgtt
     8101 tttagcgagt tagaaattaa ggatggggta tatcgattta attttgaaaa gtttgaggac
     8161 tgtattataa caaacaaagt taaagttttt gttctatgca accctcataa tcccttaggt
     8221 agggcttggg aaattgctga gttaaataaa attggaaaca tttgtttaaa gtataatccc
     8281 gactttatca cttaattttt accaagccct acttaacccc ttggtacatc tggatttccc
     8341 aactattccc caacttttgt ttgttatata tgattatgta tgattatgta tgattgtgta
     8401 tgatataata gagtatggca tttattaaaa caacaaccaa caaagaagga cgtactcatg
     8461 tctatcttgt ggaaggatat cgcaaagatg gaaaagtcag acagcgtatc ttgaaaaaat
     8521 atggttggat ggtcttggat aacctgattg aagacaaagt cctagaaaca gctatttctg
     8581 agggcttttt ttatgtcaag gagtataata gaggtaagaa gattgtaata aggtgtttgc
     8641 tatgtttcac aaagaaaatc tcgattataa ccgtcgtcaa gtaggcttct atacgcttga
     8701 agagatagtt ccaaaggacc actttctgcg ttagttggag gaaactgtcg acttttctgt
     8761 catctatgat ctagtggaga atagttattc ctcagacaag ggacgtccta gccttgaccc
     8821 tgttatgctg gtcaaaattc ctctgattca gtgcttctat ggcattcgct ccaggcgtca
     8881 gaccatcaag gacattgaga ttaatgtcgc ttatcgttgg tttctgggct tgactctgga
     8941 cgataaagtg cctcatttta ccacatacgg taagaactac agtcgtcgtt ttgctgaaac
     9001 agaattgatc acgcgtatct tcgagcatgt cctccatctc tgtttgactg ctggcttagt
     9061 ggatacagat gagattttca tcgacggaac gcaaatcaaa gcagctgcca acaaccataa
     9121 aaatagacga caagaggttg aggctcaagc taaatggatg agtgaacaac tcgacaaaga
     9181 aatagcacaa gatcggataa cacatggcaa aaagccccta aagcccgcca taaaaggcga
     9241 ggctaagacc aaaaagatgt ccatgacagc caagctttcc ctgccctttt cgcaaagcta
     9301 gcaccgtttc accccaacta tatcatcgct gactctggtt ataaaaatcc cagtattgcc
     9361 aaatgtctac tgaaccagca tatcacgcct gtcttttcct acaccagacc tcgtggcaag
     9421 aagggcatgt tacgaccgaa tgatttcatt tatgacgagc attataacgt ctacctctgt
     9481 cctgaaaacc aagtcttaca ctacagcact accaaccgtt ctgactatcg agaataagag
     9541 taaccccaag acttgtgcca cttgtctact cctaaaccgc tgtacccaaa gtaagaccaa
     9601 gcagaagctg gtcaccagat atgtctcgtt actacttttt gaaaattctt gctttgggta
     9661 caaatggata ataaaggaca ggaaacacat actttgggat tactcttata ctcacggtag
     9721 ccttctcgag tggtagtgag atagcttaat acttgattcc tggacagaca taatggtcat
     9781 aacttgcatc ataaacaaaa ttactaggcc ttaagttccc ctttactccc tttggacgag
     9841 tataagggaa aacaggaatg atattacgtt ctaacaaata atgggcaata gcttgggtct
     9901 tgtaacctga atctgcaata atatagtggg gggagaatgg ctctaacttt gaaaataggg
     9961 cagggaaagc ttgactatca tgaacatttc ctgcttcaac cgtataagct aaggaccatc
    10021 catgcttatc acaagcaact tgggcagaat aggcaaatac ttccttgtgt tcgcccttgt
    10081 gaaacaaacc acactcggga tctgtcgttg agattttctt ttccttagct tcactttctt
    10141 ttgcgggctt taaggacttt tttcgtgttt tttcttatct aaatcaatct caactgccaa
    10201 ttgttcactc ataaatctag cttgttggtc taccatttcc ttacgggact tgtgactatt
    10261 agctgccact ttgatatggg taccatccac aaatatttca gaagaatcaa ttaaggcaac
    10321 atacaaagct tggttgagaa cttgggaaaa atctcagaaa tgagttcttt atcttgaaaa
    10381 cgacggctgt aattctttcc ataggcagta aaatgaggga ccttatcatc taaagttagt
    10441 ccaagaaacc aacgataggc cacgtttact tcaatctctt tcatggtttg gcgcatggaa
    10501 cgaatgccat aaaaacattt gatttaagga attttgacta atatgacggg atcaagacta
    10561 ggacgaccat tatctggact ataggtatct tctaccaagt catagataaa gtcaaaatca
    10621 accttggaat ctacttgtcg aagaaagtga tcttctggga ccaattcgtc tattgtatag
    10681 aaaccatatt acttacgatt ataatcaggt ttttctttgt gaaacataag gaacacctca
    10741 caactcttct tacctctatt atacgacttt acacaaagaa aagcccttgg aagcttgact
    10801 tccaatgact gtatcttcgg tctgaaactt ctagagtcaa caaagacttt ggaagttttc
    10861 aatataatct gttattggac ggttacgtag tttctgatta ttctttaaaa taaattattt
    10921 atgcaagttt tgcatagaac cccatcttta tttttagaat tactaaaata gtaattggaa
    10981 ggggttctat gtatattcgg gtaaaaaatt taagagaaga cagtgactat aatcagagtc
    11041 aaattgcaca atatctaaat tgttctcaat ctacttattc cagaattgag agtggtattc
    11101 aggatattcc tactcagttt ttaaaaaaat tagcaaagtt atatggagta actacggatt
    11161 ttttactaga gatggataag gaataatacc cttcttttgt tccttgacaa ctgaatagac
    11221 caaggtggga ctttaatcat ttgtggagca agttagttag atacgctgtg atatgagcga
    11281 gaattatcag ctataaaata gagtggtact ctatctgcca tgatacaagt gaagataatg
    11341 atacttctaa ccgtttaggc tgccagcgag aaaggacagc gggtgtaagc cccatgtaga
    11401 acttaaccag ttctacccat tgaggtcaac attttgacgt aaaggaaata acatttatgg
    11461 aaaaaacaca aacaggtgcg gatttaccgc aagtcgtgat tgagggctat aaggtgacgg
    11521 tacgagttac cgataaacca ttaagcctaa cagatgtttt agatgattta ctgggacggc
    11581 agctggaaaa aatttgattt tttagcggac aagtcttgat aaatgatgta aaatagaata
    11641 gtagaacctc agtccttaat cggtaagcac ctaaataact gattaaggag acaaacatga
    11701 cacgagcctg tacttattta cgcttatcac gagatgatgg ggataacgta gagagtaatt
    11761 ccatcatcaa ccaacgctcg ctcttgcgag attatgctag gaggcatgac ttcaccattt
    11821 tagaagaatt tgtggatgat ggtattagtg gactgacctt taaccgtcca gactttaacc
    11881 gtatgatggt aatggtaaat aacaagacca ttgataccat tatcgtgaaa gacctgtctc
    11941 gctttggtcg agactatatt gaaactggaa aatacctcca gcgaattttt cctgctatgg
    12001 ggatccgttt tatctcagtt aatgaccatt atgatagctt gacggctgat accaatgaaa
    12061 ctcatctggt catgcccatt aaaagcctca ttaacgatag ctattgtcgg gacatttcaa
    12121 ctaaagtgcg aagtactcaa aaagccaaac ggcaaaaggg agagtttatt ggggcttttg
    12181 ctccttatgg ctatcgtaaa gaccataatc aacgaaacca tttagtggtt gatgaagcag
    12241 ttcgctccac tatcgaaaca atctttgctc tgaaattgga aggatattct tctaatgcca
    12301 ttgcgaattt tttgaatcaa gctggggtgg aaacacctct acaacgtaag agagcctgtc
    12361 aggaaaggat taaaggcttc tatggttatc gtcataagtg ggataccaaa atggtcaatc
    12421 gtatcctgac caatcgtgtc tatactggca ctttagaaca aggaaaacag accaaactta
    12481 attataagtc tcaaaagtct gtggctgtca atccagaaga ttgggtacga gtggaagata
    12541 cccacgaagc cattatctcc acaagtacct tttctattgc gaataacctc ttactcagag
    12601 atgtcaaaca tggaaagaat actcctgacc tctttgcagg actcttgttt tgtggcgact
    12661 gccaggcaca actcttgcag cggaaacttc gttacaagga caaagaaact gttcagtata
    12721 tttgtagcac ctacaacaac ggtcaaggct gtagtcgtca tgctattaag gaagatgtgc
    12781 taaccgattt agtatcaact atcgttcatc agcatcttga ttggaagtct tatctagtaa
    12841 aatctattcc tgattatctt gaccaggaac actttttaga ggttgatttt acttctttga
    12901 tttcggagcg tcaaaagtat gagcagttgc ttcagtccct gtatctggat ttagatgacg
    12961 gattaatcaa tgaaacagaa taccaagagt ttcagcgtag ctatcgccaa aagctaaagc
    13021 aaattgaaga cactatcgtt caaaagaaag aattggctca aaccctctac gataagctcc
    13081 aggataagga gacttggctt gagcagttga gcacgataca acatgagcaa gagcttaatc
    13141 gtctcactct agtgacttta ctggatcgta ttatcgttca tgaacaacaa gcattaacct
    13201 tgatgtttca cgatgtggca gaattgtccc ttcttcaaca gttttctaac atggaggtgg
    13261 tctaatggca cgtactaaga accgctcccg tgtagaaacg gtagaaaaga tacctcttca
    13321 aacctatcga acaggtattt atattcgatt atccaaagaa cgtaccgaaa gttggcgaca
    13381 taaatcgcag tctttaaaga cccaggaaag tctagctaga acctttgccc aagaaaaagg
    13441 tttaacagtc accaagtgct atattgatta tgaatattct ggcacaaaat ttaatcgccc
    13501 agcctatcaa gatatgatgg aagacatcaa gagaggtgtc atcaattgta tcttgattcg
    13561 agacttatca cgcttagggc gtaactacat tgagattggg cgactgattg ataaggtatt
    13621 tccctttatg ggggttcggt ttatttcaat caatgataac ctagatactc tcaatgggct
    13681 agaagataag aaatcctttg aagtggaaat taagaatttg gtcaatgacc tttattctaa
    13741 ggacatttca aagaaagtta tgtcctataa tattcaccaa gctagtcaag gatactatat
    13801 tggaacatct gctccgtatg gttatcgaat tgatcgccaa gaagcaggtg cgaggttagt
    13861 tattgataac caagtcaagc caattttaga gtttattttt caacaggcaa ttgaaggtgt
    13921 atccatatct cagattacta ctgaattgaa tcatagagga attgctgtac ctcagtcata
    13981 ccgtgggact ggccaattgt atagaagtga acaggatatc aaaagatggc atgcaggaaa
    14041 tttgcttcgt cttatcaaaa tgcctgttta caggggagtt cttattcaac gaacacggaa
    14101 caaatcgtta tctgaagagg attatatcca ttttgaaaat gctcaagaag cctatgtcag
    14161 caaagataac tacgaaaaaa tactttttta tctagatagt cgtaagtccg ttaaaaagac
    14221 tagtatagtg agaactccaa accgctatag aggtctggtt tacgccaaaa caaaatcaac
    14281 tcaaatggtt cgcagatgtc gccatttctc aaacaataag tctgattatg attactatta
    14341 ttttacggac tatatctatg attcagagac aactgagaga aaaaccgtct atatcagtga
    14401 aaatgctctg gacaagatta tagtagagtt gatccaatca gaaatgaagc ggttaggaac
    14461 agttgagaca ttgttgccac ggttagaaac taaaaaagac gattgcctaa agacgtatca
    14521 caagcaaata acttgtcatc aatggaccat cacacagcta caagctgagc taagtgacct
    14581 ttatgcgtct tttagtctta atcgttctga acgagaagtc tatctctccc aaaagaacga
    14641 gataatcgca aaaattgaaa ccatttcaca agaaatagcc ttatgtgaaa cctcaataaa
    14701 gcagattgag gaggagcaca gtaagcaggt gaattgggtt agacatctag ccaagagcca
    14761 aaatcaagtt gttttaacgg cagaactctt aaatgcttta atagaacgga ttgaggttga
    14821 tgtagacaaa acagtgacag taactttcag ctgtcagatt gggggtggcg agcatgacta
    14881 aaatcgctct atatctccgc ttgtcagttg atgaggctga tacagatgaa agcaactcaa
    14941 ttacgaacca acggtacttg ttaaacaatt atctcgacca aacacctgag ttcaagaatt
    15001 gggaacgctt ggaatttgtg gacgatggtt tttcaggaac cagtcttaaa cgtccagcct
    15061 ttcaacgcat gatggccgat gtcaaggctg gaactatccg tcatatcatc gttaaagact
    15121 tgtcacgatt tatgagagac tatctggagt tgggaaacta cttagagaat atctttcctt
    15181 ttctcggagt tcgatttatc gctctcaacg accattatga tagcctggtg tctgaacata
    15241 atggactgga tattgatgtg ccctttagaa acttactcaa tgatttctac gccaaagacg
    15301 tttctgaaaa agtcaagagt gcaatgaaca gtatgaaacg ctctgggaag aacatgagtt
    15361 ggttaccacc gtttggttat atcaaggacc caaatgaccg atttaagatt atcattgatg
    15421 aggaagtcgc tccaattgtg agacgaattt ttagactttg cattgaggga atgggaactc
    15481 aaaaaatagc gatgttactt aatagtgaac agacgattac tccagctgag aggaaaatgc
    15541 aggttagtca agcaaggtat acaaaatcaa ttatcattac tgccgaacaa aagaggaatg
    15601 tatggacgag aagtggtatt ctccaaatac tcaaaaatga agcctataag gggacatacc
    15661 tgtttaacac tagaacaacg gtaaatggta agcagattcg gcggcctgaa tcagagtggg
    15721 aacgtcttga caataatcat gaggcaattg tatcaagtga ggactttgac aaagctcaac
    15781 aatcacttac ctctcgcatt agtgggacga aaagtcaggt ttgtaatcag ccagaagaag
    15841 ttttattgag aggcttagtt atctgtgaac attgtgggca tcgtctcctt cgatatagcc
    15901 acaataacaa caataattat ttttattgtt gttattgtag aagccaaggc cagaatatga
    15961 agtcctgtcg gatagataga atagaagagg ctatcgagaa agaattaaag tctcggttgc
    16021 cgatgaactc tccaaagcta tcaaaaacga atcttataag agaagttgaa cggctgaaaa
    16081 ctcaaaaggt ttctcatttt caagactata aagagggctt gatgacaaga gaaacttaca
    16141 tggaaaaacg tcagaactta gataattcta taatggaaat agaagaacaa ttaaaggtag
    16201 ttggtaggga aaatatagca tttgacaaga aattgaccag agaagtagtt gacactcata
    16261 tcgagaggat tgtcgtcaat ggccaaggtt cttttacagt cgtctataaa taacctaatg
    16321 agagacttgt gtaatagcaa gtctctttct tgaaaagtag ctttgtggta taataagggt
    16381 gttttcagtg tagaaaaata gtgtc
//
LOCUS       DAVDHZ010000047        16234 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000047 DAVDHZ010000000
VERSION     DAVDHZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16234
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.048"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..145
                     /locus_tag="VUR46_001831"
     CDS             <1..145
                     /locus_tag="VUR46_001831"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457199.1"
                     /translation="HGFEVVDETDEVSSKHGFEVVDETDEVSNHIYGKATLTKFELDF
                     RRV"
     gene            233..6934
                     /locus_tag="VUR46_001832"
     CDS             233..6934
                     /locus_tag="VUR46_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET5457200.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHTVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7182..8038)
                     /locus_tag="VUR46_001833"
                     /pseudo
     CDS             complement(7182..8038)
                     /locus_tag="VUR46_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8248..8607)
                     /locus_tag="VUR46_001834"
     CDS             complement(8248..8607)
                     /locus_tag="VUR46_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET5457201.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8630..9208
                     /locus_tag="VUR46_001835"
     CDS             8630..9208
                     /locus_tag="VUR46_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846832.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HET5457202.1"
                     /translation="METRNRGIYRKVRLLRLWVIFVIMKVIKSYNTLNDYYRKLFGEK
                     TFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKW
                     PDVQKYLVYFQNFTNTHEKVEVIRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAE
                     LSECMHVTVELGLQTTYEATSDLINRAHSYEL"
     gene            9227..9655
                     /locus_tag="VUR46_001836"
     CDS             9227..9655
                     /locus_tag="VUR46_001836"
                     /inference="COORDINATES: protein motif:HMM:NF027524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457203.1"
                     /translation="MRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLKKWEVLNSIEMEMRRRGSVQGCKVVKQEFENEKTT"
     gene            9639..10196
                     /locus_tag="VUR46_001837"
     CDS             9639..10196
                     /locus_tag="VUR46_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5457204.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10189..10443
                     /locus_tag="VUR46_001838"
     CDS             10189..10443
                     /locus_tag="VUR46_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457205.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10455..12509
                     /locus_tag="VUR46_001839"
     CDS             10455..12509
                     /locus_tag="VUR46_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET5457206.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAD
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12688..13548
                     /locus_tag="VUR46_001840"
     CDS             12688..13548
                     /locus_tag="VUR46_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET5457207.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13759..14469
                     /gene="ccdA2"
                     /locus_tag="VUR46_001841"
     CDS             13759..14469
                     /gene="ccdA2"
                     /locus_tag="VUR46_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET5457208.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14489..15055
                     /locus_tag="VUR46_001842"
     CDS             14489..15055
                     /locus_tag="VUR46_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET5457209.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            15066..16178
                     /gene="msrB"
                     /locus_tag="VUR46_001843"
     CDS             15066..16178
                     /gene="msrB"
                     /locus_tag="VUR46_001843"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET5457210.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVN"
BASE COUNT         4916 a         3070 c         3612 g         4636 t
ORIGIN      
        1 acatggtttt gaggttgtag atgaaactga cgaagtcagc tcaaaacatg gttttgaggt
       61 tgtagatgaa actgacgaag tcagtaatca tatctacggc aaggcgacac tgacgaagtt
      121 tgaattggat tttcgcagag tgtaaattgt tgaaactagg ttgtcatacc atgtatacca
      181 cttgggcttt agtagtagct aactgcacta aatataatat aaggagggtt ttatggggaa
      241 aggccattgg aatcggaaaa gagtttatag cattcgtaag tttgctgtgg gagcttgctc
      301 agtaatgatt gggacttgtg cagttctatt aggaggaaat atagctggag aatctgtagt
      361 ttatgcggat gaaacactta ttactcatac tgctgagaaa cctaaagagg aaaaaatgat
      421 agtagaagaa aaggctgata aagctttgga aactaaaaat gtagttgaaa ggacagaaca
      481 aagtgaacct agttcaactg aggctattgc atctgagaag aaagaagatg aagccgtaac
      541 tccaaaagag gaaaaagtgt ctgctaaacc ggaagaaaaa gctccaagga tagaatcaca
      601 agcttcaagt caagaaaaac cgctcaagga agatgctaaa gctgtaacaa atgaagaagt
      661 gaatcaaatg attgaagaca ggaaagtgga ttttaatcaa aattggtact ttaaactcaa
      721 cgcaaattct aaggaagcca ttaaacctga tgcagacgta tctacgtgga aaaaattaga
      781 tttaccgtat gactggagta tctttaacga tttcgatcat gaatctcctg cacaaaatga
      841 aggtggacag ctcaacggtg gggaagcttg gtatcgcaag actttcaaac tagatgaaaa
      901 agacctcaag aaaaatgttc gccttacttt tgatggcgtc tatatggatt ctcaagttta
      961 tgtcaatggt cagttagtgg ggcattatcc aaatggttat aaccagttct catacgatat
     1021 caccaaatac cttcacaaag atggtcgtga gaatgtgatt gctgtccatg cagtcaacaa
     1081 acagccaagt agccgttggt attcaggaag tggtatctat cgtgatgtga ctttacaagt
     1141 gacagataag gtgcatgttg agaaaaatgg gacaactatt ttaacaccaa aacttgaaga
     1201 acaacaacat ggcaaggttg aaactcatgt gaccagcaaa atcgtcaata cggacgacaa
     1261 agaccatgaa cttgtagccg aatatcaaat cgttgaacga ggtggtcata ctgtaacagg
     1321 cttagttcgt acagcgagtc gtaccttaaa agcacatgaa tcaacaagcc tagatgcgat
     1381 tttagaagtt gaaagaccaa aactctggac cgttttaaat gacaaacctg ccttgtacga
     1441 attgattacg cgtgtttacc gtgacggtca attggttgat gctaagaagg atttgtttgg
     1501 ttaccgttac tatcactgga ctccaaatga aggtttctct ttgaatggtg aacgtattaa
     1561 attccatgga gtatccttgc accacgacca tggggcgctt ggagcagaag aaaactataa
     1621 agcagaatat cgccgtctca aacaaatgaa ggagatggga gttaactcca tccgtacaac
     1681 ccacaaccct gctagtgagc aaaccttgca aatcgcagca gaactaggtt tactcgttca
     1741 ggaagaggcc tttgatacgt ggtatggtgg caagaaacct tatgactatg gacgtttctt
     1801 tgaaaaagat gccactcacc cagaagctcg aaaaggtgaa aaatggtctg attttgacct
     1861 acgtaccatg gtcgaaagag gcaaaaacaa ccctgctatc ttcatgtggt caattggtaa
     1921 tgaaataggt gaagctaatg gtgatgccca ctctttagca actgttaaac gtttggttaa
     1981 ggttatcaag gatgttgata agactcgcta tgttaccatg ggagcagata aattccgttt
     2041 cggtaatggt agcggagggc atgagaaaat tgctgatgaa ctcgatgctg ttggatttaa
     2101 ctattctgaa gataattaca aagcccttag agctaagcat ccaaaatggt tgatttatgg
     2161 atcagaaaca tcttcagcta cccgtacacg tggaagttac tatcgccctg aacgtgaatt
     2221 gaaacatagc aatggacctg agcgtaatta tgaacagtca gattatggaa atgatcgtgt
     2281 gggttggggg aaaacagcaa ccgcttcatg gacttttgac cgtgacaacg ctggctatgc
     2341 tggacagttt atctggacag gtacggacta tattggtgaa cctacaccat ggcacaacca
     2401 aaatcaaact cctgttaaga gctcttactt tggtatcgta gatacagccg gcattccaaa
     2461 acatgacttc tatctctacc aaagccaatg ggtttctgtt aagaagaaac cgatggtaca
     2521 ccttcttcct cactggaact gggaaaacaa agaattagca tccaaagtag ctgactcaga
     2581 aggtaagatt ccagttcgtg cttattcgaa tgcttctagt gtagaattgt tcttgaatgg
     2641 aaaatctctt ggtcttaaga ctttcaataa aaaacaaacc agcgatgggc ggacttacca
     2701 agaaggtgca aatgctaatg aactttatct tgaatggaaa gttgcctatc aaccaggtac
     2761 cttggaagca attgctcgtg atgaatctgg caaggaaatt gctcgagata agattacgac
     2821 tgctggtaag ccagcggcag ttcgtcttat taaggaagac catgcgattg cagcagatgg
     2881 aaaagacttg acttacatct actatgaaat tgttgacagc caggggaatg tggttccaac
     2941 tgctaataat ctggttcgct tccaattgca tggtcaaggt caactggtcg gtgtagataa
     3001 cggagaacaa gccagccgtg aacgctataa ggcgcaagca gatggttctt ggattcgtaa
     3061 agcatttaat ggtaaaggtg ttgccattgt caaatcaact gaacaagcag ggaaattcac
     3121 ccttactgcc cactctgatc tcttgaaatc gaaccaagtc actgtcttta ctggtaagaa
     3181 agaaggacaa gagaagactg ttttggggac agaagtgcca aaagtacaga ccattattgg
     3241 agaggcacct gaaatgccta ccactgttcc gtttgtatac agtgatggta gccgtgcaga
     3301 acgtcctgta acctggtctt cagtagatgt gagcaagcct ggtattgtaa cggtgaaagg
     3361 tatggctgac ggacgagaag tagaagctcg tgtagaagtg attgctctta aatcagagct
     3421 accagttgtg aaacgtattg ctccaaatac tgacttgaat tctgtagaca aatctgtttc
     3481 ttatgttttg actgatggaa gtgtacaaga gtacgaagta gatagctggg agattacgga
     3541 agtagataaa gccaaacttt cagtagctgg atcacgtatt caaatgactg gtcagttagc
     3601 tggagaaact attcatgcaa cccttgtggt agaagaagga aatgctgcag cacctgtagt
     3661 gccaactgtt actgttggag gtgaagcagt aacaggtctt actagtcgac aaccaatgca
     3721 atatcgtact ctatcttatg gtgcccaatt gccagaagtc acagcaagtg ctgaaaatgc
     3781 tgatgtgaca gttcttcaag caagcgcagc aaacggcatg cgtgcaagca tatttgttca
     3841 gcctaaagat ggtggccctc ttcaaaccta tgcaattcaa ttcctagaag aagcaccaaa
     3901 aattgctcac ttgagcttgc aagtggaaaa agctgacagt ctcaaagaag accaaactgt
     3961 caaattgtcg gttcgagctc actatcaaga tggaacgcaa gctgtattac cagctgataa
     4021 agtaaccttc tctacaagtg gtgaagggga agtcgcaatt cgtaaaggaa tgcttgagtt
     4081 gcataagcca ggagcagtca ctctgaacgc tgaatatgag ggagctaaag gccaagttga
     4141 actcactatc caagccaata ctgagaagaa gattgcgcaa tccatccgtc ctgtaaatgt
     4201 agtgacagat ttgcatcagg aaccaagtct tccagcaaca gtaacagttg agtatgacaa
     4261 aggtttccct aaaactcata aagtcacttg gcaagctatt ccgaaagaaa aactagactc
     4321 ctatcaaaca tttgaagtac taggtaaagt tgaaggaatt gaccttgaag cgcgtgcaaa
     4381 agtctctgta gaaggtatcg tttcagttga agaagtcagt gtgacaactc caatcgcaga
     4441 agcaccacaa ttaccagaaa gcgttcggac atatgattca aatggtcacg tttcatcagc
     4501 taaggttgca tgggatgcga ttcgtccaga gcaatacgct aaggaaggtg tctttacagt
     4561 taatggtcgc ttagaaggta cgcaattaac aactaaactt catgttcgcg tatctgctca
     4621 aactgagcaa ggtgcaaaca tttctgacca atggaccggt tcagaattgc cacttgcctt
     4681 tgcttcagat tcaaatccaa gcgacccagt ttcaaatgtt aatgacaagc tcatttccta
     4741 caataaccaa ccagccaatc gttggacaaa ctggaatcgt agtaatccag aagcttcagt
     4801 cggtgttctg tttggagatt caggtatctt gagcaaacgc tccgttgata atctaagtgt
     4861 cggattccac gaagaccatg gagttggtgc accgaagtct tatgtgattg agtattatgt
     4921 tggtaagact gtcccaacag ctcctaaaaa ccctagtttt gttggtaatg aggaccatgt
     4981 ctttaatgat tctgccaact ggaaaccagt tactaatcta aaagcccctg ctcaactcaa
     5041 ggctggagaa atgaaccact ttagctttga taaagttgaa acctatgcta ttcgtattcg
     5101 catggttaaa gcagataaca agcgtggaac gtctatcaca gaggtacaaa tctttgcgaa
     5161 acaagttgcg gcagccaagc aaggacaaac aagaatccaa gttgacggca aagacttagc
     5221 aaacttcaac cctgatttga cagactacta ccttgagtct gtagatggaa aagttccggc
     5281 agtcacagca aatgttagca acaatggtct cgctaccgtc gttccaagcg ttcgtgaagg
     5341 tgagccagtt cgtgtcatcg cgaaagctga aaatggcgac attttaggag aataccgtct
     5401 gcacttcact aaggataaga acttactttc tcataaacca gttgctgcgg ttaaacaagc
     5461 tcgcttgcta caagtaggtc aagcacttga attgccgact aaggttccag tttacttcac
     5521 aggtaaagac ggctacgaaa caaaaaacct gacagttgaa tgggaagaag ttccagcgga
     5581 aaatctgata aaagcaggtc aatttaccgt tcgaggccat gtccttggta gtgatcttgt
     5641 tgctgaggtc actgtacgag tgacagacaa actaggcgaa gctctttcag ataaccctaa
     5701 ctatgatgaa aacagtaacc aggcctttgc ttcagcaacc aatgatattg acaaaaactc
     5761 tcatgaccgc gttgactatc tcaatgacgg agatcattca gaaaatcgtc gttggacaaa
     5821 ctggtctcca acaccatctt ctaatccaga agtatcagcg ggtgtgatct tccgtgaaaa
     5881 tggtaagatt gtagaacgga ctgttgctca agccaaactt cacttctttg cagatagtgg
     5941 tacggatgca ccaactaaac tcgttttaga acgctatgtc ggtccagagt ttgaagtgcc
     6001 aacctactat tcaaactacc aagcctacga cgcagaccat ccattcaaca atccagaaaa
     6061 ttgggaagct gtgccttatc gtgcggataa agacatcgca gctggtgatg aaatcaacgt
     6121 aacatttaaa gctgtcaaag ccaaagctat gagatggcgt atggagcgta aagcagataa
     6181 gagcggtgtt gcgatgattg agatgacctt ccttgcacca agtgaattgc ctcaagaaag
     6241 cacgcaatcg aagattcttg tagatggaaa agaacttgct gatttcgctg aaaatcgtca
     6301 agactatcaa attacctata aaggtcaacg gccaaaagtc tcagttgaag aaaacaatca
     6361 agtagcttca actgtggtag atagtggaga agatagcctt ccagtacttg ttcgcctcgt
     6421 ttcagaaagt ggaaaacaag tcaaggaata ccgtatccag ttgactaagg aaaaaccagt
     6481 ttctgagaag acagttgctg ctgtacaaga agatcttcca aaactcgaat ttgttgaaaa
     6541 agatttggcc tacaagacag ttgagaaaaa agattcaaca ctgtatctag gtgaaactcg
     6601 tgtagaacaa gaaggaaaaa ctggtaaaga acgtatcttt acagcgatta atcctgatgg
     6661 aagtaaggaa gaaaaactcc gtgaagtggt agaagctccg acagaccgca tcgtcttggt
     6721 tggaaccaaa ccagtagctc aagaagctaa aaaaccacaa gtgtcagaaa aagcagatac
     6781 aaaaccaatt gattcaagtg aagctagtca aactaataaa gcccagttac caaatacagg
     6841 tagtgcggca agccaagcag cagtagcagc aggtttagct cttctaggtt tgagtgcagg
     6901 attagtagtt actaaaggta aaaaagaaga ctagaaattt tgataccttc tttatcatta
     6961 aagaccaaag aaaaactctt gtcctaaata gaagataaag agtctggaac aaaatagttc
     7021 tcaaccacaa aaaagctaga tatttccaat tgcggaactc tagcttttta attttgagtc
     7081 gttctcttat tgtatagtag attgaaacta gagtagtaca cttctacttc taaaacattg
     7141 ttagaaatcg atttgactgt ccttatcgat ttgtcctgtt cttatttcat ttcactatgt
     7201 tttaggaggt tattggccat aagtaccaat cccatgtcaa ttctcacttg acgcttgcct
     7261 ctcagattac atctcttgta acccaaacaa gcctttatct gcccaaagac aggttctaca
     7321 tcaatcttgc gttgagcgaa aatctgtcta tcttggggag ataaaagcgc ctgacattct
     7381 ttagctttca agttttgata gcgttcgttc atatacaatc ccttttgagg ggctgattca
     7441 ggttcgtcgg cgtagtaaac cttgatttct tgttgaaagt ctgtctgtgt tttctggtac
     7501 ttgatatggt gaaaacgata gcaccagcca tcaggatgta tgtagctatc ctccttgtca
     7561 ttatagtgcc aattcgctaa gtttttagct gactgtttat accctctctt ttgtttctta
     7621 tcaaacatgg catatttaat cagaagggga gtgatttctt cttgaaaata gacttgtatc
     7681 tgttcttgaa gtttggcgga gaatttctct gtcgttttct tccacacaaa actatacttg
     7741 ttggcattgg cttcaatctt agttccgtca ataaacaaac aatctaaggt cactaactct
     7801 tccatttttc aatttttcga ccagagaaaa tcccttgtga ataggcaaat agaagagtag
     7861 atacaagcat tttagggtga taagacgggc gaccaaaggc atgatagaag gcgtagaagt
     7921 gacgttcctc caaggtattc accacttttt caatagtaaa gacgagatgg tcttgtggta
     7981 agaaggaact gatttctagt ggtaaagttg tttgatttgt gttatagtga atatgcatgg
     8041 gatagtcttt ctaaatggtt tattaagcaa ttctatttta ccaagactat cgtaaccatg
     8101 caaaaaagca acggcaaatc cgttgccttt ttggatataa gagactattg tcccagactc
     8161 ttttctttgt ataaaattgt atagtgttat tgtctatact attttgtaga gaaagcaaaa
     8221 atccctagaa aatgcttagg gattcgacta tttcattaag aacaattcaa caatcatttc
     8281 tatatacatg ataagggtta ataagaatcc tgcacgccag aagaatttga tgaatttagg
     8341 atagtaaaag ctgcgttttt ttaaaaggaa gaaaaagacg agaataatgg ctaggaacga
     8401 gagggctagc cccagtctag ggaggaaatt atgggtaaag gttttagctg taatcaagta
     8461 atactcaaat accaagactg gaaaagccaa atccgcaaag tttcgtccta gtttttttaa
     8521 tctaaaaagt ttggttagga taatgcagac gactaaggtc agtatcaata ataaaataga
     8581 tgctaatttc attaaaatca tacccatatt gtatcataaa aaaaggctaa tggaaacgag
     8641 aaacagagga atttatagga aagtcaggct tttgagattg tgggtgattt ttgttataat
     8701 gaaagttata aaatcttata ataccttgaa tgattattat cgaaaactgt ttggagaaaa
     8761 gacttttaaa gtccctattg atgcgggatt tgactgtccc aatcgtgatg gaactgtggc
     8821 tcatggaggc tgtacttttt gtacggtttc aggttctgga gatgctattg tagccccaga
     8881 tgcgcctatc cgtgagcaat tttataagga aattgacttt atgcaccgta agtggccgga
     8941 tgttcagaag tatctggttt attttcaaaa ttttaccaac acccatgaaa aggtggaagt
     9001 tattcgagag cgttatgaac aggctatcaa tgagccaggt gtggtaggaa tcaatattgg
     9061 aacgcgccca gactgtttac cagacgaaac catcgaatat ttggctgagt tatcggagtg
     9121 catgcatgtg acggttgaat tgggcttgca aactacttat gaagcaacct ctgacctgat
     9181 taaccgtgcg cattcttatg aattgtaggt ggaaacggtc aagcgtttga gaaagtatcc
     9241 caagattgag attgtttccc atttgataaa tggtttgcct ggtgaaaccc atgagatgat
     9301 ggttgaaaat gtccgccgtt gtgtcacgga taacgatatt caagggatta aactgcattt
     9361 gctccatctt atgacaaata ctcgtatgca acgagattac catgagggac gtttacaatt
     9421 gatgagtcag gacgaatatg tcagggtcat ctgtgaccaa ctggaaatta ttcccaaaca
     9481 tatcgtcatc catcgaatta caggagatgc gcctagggat atgctgattg gtcctatgtg
     9541 gagcctcaaa aaatgggaag tcctcaacag cattgagatg gagatgcgac gtcgtggaag
     9601 tgttcaagga tgcaaggttg taaaacagga gtttgaaaat gaaaagacca cttgagatgg
     9661 cacatgattt tttggctgag gtcgtgacaa aagaggatgt cgtagtggat gcgactatgg
     9721 gaaatggtca tgacacgctt tttttagcca agctagccaa gcaagtctat gcctttgata
     9781 ttcagaagca agccttggaa aagacccaag agcgtttgca tcaggctggc ttgacaaatg
     9841 cccagttaat cttgcaaggc catgagacac tggaccagtt tgtgacaaaa gctaaggcag
     9901 ggatttttaa tctgggctat ttgccgtcag ctgataagtc tgtcatcacc cgaccgcaga
     9961 caacgattga ggcattagaa aagctatgtg gcttacttgt caaaggtgga cgaattgcta
    10021 ttatgattta ctatggtcat gaaggaggcg acctcgagag agatgctgtc ttggattttg
    10081 tgatccagtt gaaccaacaa gagtacacag ctgccattta ccgaacttta aaccaagtca
    10141 acaacccgcc gtttttagtg atgattgaaa aattagagag atacagacat ggataaacaa
    10201 tacctacacg aaaagctgga tgccatgcgc cagaattttg ttgaatcaac tcaccacgaa
    10261 cgagcggtgg gcgtgctaga ccaagcgcat atgagcaaaa aaatgcttaa aatcaagaaa
    10321 aaattagttg ctcttgaaat ggaacggtgc cagagaaaaa ttgagcacaa agactgttcc
    10381 aagattgacc aaaaaatcaa agagcagaag gagatatttg aatcctgttg taaaaaagat
    10441 taaggaggac gtgcgtggaa ttactgattt acctcatcct atttttactg gttttgattg
    10501 tctcaagtac aaccaataag ctcctgccct ttttgcctct ccctttggtg caaattcttt
    10561 tgggaattgt gattggtctc tttttaccca ataccgactt tcacctcaat acggagttgt
    10621 ttttggccct ggttatcgga cccttgcttt tccgagaggc tgaagaagca gatgttacgg
    10681 ctattttaaa acactggcga atcattgttt atctcatatt tccagtgatt tttatctcga
    10741 ccctgagttt gggtggcttg gcccatcttc tttggttcag ccttcccttg gcagcttgct
    10801 tggctgttgg ggcagccctt ggtcctacgg acttggtggc ctttgcctct ctttcggagc
    10861 gttttagctt tcctaagcgc gtgtccaata ttcttaaggg cgaaggactc ttgaatgatg
    10921 cttctggttt ggtggctttt caggtagctt tgacagcttg gacaactgga gctttttctc
    10981 tggggcaagc tagcagttcg ctcatctttt caatcctagg cggtttttta attggatttt
    11041 taacagccat gaccaaccgc ttcctccata ccttcttgct aagtgtgcgc gcaacggata
    11101 ttgccagtga acttttatta gaattgagtt tgcctctagt gaccttcttt ctggcagaag
    11161 aagtccatgt ttcagggatt attgccgtcg tagttgctgg aattttaaag gcaagtcgct
    11221 tcaagaaaat cacgctcctc gaagcccaag tggatacggt gaccgagacg gtctggcata
    11281 cagtgacctt tatgctcaac ggttctgtct ttgtgatttt agggatggag ttggaaatga
    11341 tagcagaacc tatcttgacc aatccaatct ataatcctct acttttattg ctatctctca
    11401 tcgcccttac ctttgtcctc tttgtcattc gttttattat gatctatggc tattatgcct
    11461 atagaacccg acgcctcaag aaaaagctaa ataagtatat gaaggacatg tttctcttga
    11521 ccttttcagg tgttaaggga acggtgtcga ttgctacgat tctcttgata ccaagtaatc
    11581 tagaacagga gtatcctctc ttgcttttcc ttgttgcagg tgtgacgctt gtcagctttt
    11641 taacaggtct cttggtcttg cctcatcttt ctgatgaaga ggaagaaagc aaggattatc
    11701 tcatgcatat cgccattttg aatgaagtaa cgctagagtt ggaaaaagag ttggaagaca
    11761 ccagaaataa acttcccctc tatgcggcta ttgacaatta tcatggacgt attgaaaatc
    11821 tcattttaag ccaagaaaac caggatgatc aagaagactg ggctgctttg aaactcttga
    11881 ttcttagtat tgaaagtgat ggtttggaac aggcctatga agaggggaac attagcaatc
    11941 gtgcttaccg agtttaccaa cgttatctga aaaatataga acaaggaatc aatcgtaaac
    12001 ttgcctcaag actgacctat tattttcttg tttccttgag gattttacgt tttctccttc
    12061 atgaagtttt tactcttgga aagaccttcc gtagctggaa ggacaaggag caaagccgtc
    12121 tccgtgctct tgattatgac caaattgcag atctctatct tgccaatacg gagatgatta
    12181 ttgaaagttt ggaaaacctg aagggagtct acagacgctc tttgattagt tttatgcagg
    12241 agtctcgtct tcgagaaaca gctattatca gcagtggtgc ctttgtcgaa cgggttatca
    12301 atcgtgtcaa acccaacaat atcgatgaaa tgctgagagg ctattatctg gagcgcaagt
    12361 tgattttcga atacgaagaa aaacgattga ttacgactaa gtatgccaag aaattacgac
    12421 aaaatgtcaa taacttagag aactattcct tgaaggaagc tgccaatacc ctaccgtatg
    12481 atatggtgga attggtaaga agaaattagt taatactctt cgaaaatctc ttcaaaccac
    12541 gtcagcgtcg ccttaccgta tgtatgtgac tgacttcgtc agtcttatct acaacctcaa
    12601 aacagtgttt tgagcagctt gcggctagct ttctagtttg ctctttgatt ttcattgagt
    12661 ataagattat aagtgaagga gtatgacatg aaaaagtggt ggaaagagct gatagacaaa
    12721 cctttattaa aagctttttt gcattattat caagcatcag atagtgagtt gaccagtgtc
    12781 gcagtagcct actattggtt gatttcgatt ttccccctgc ttttggtggt ggtcaatatc
    12841 ctcccctatt ttcagattcc tgtgggagaa tttctgggct ttatgaaaga cgtcctgccc
    12901 ccaagcctct atgaaggtgt ggaaaaaata gccagagaag tcttgacgca accttcaaca
    12961 ggtttattga gtttttctgt tttatcggcg ttatggagtt tttcaaaatc tatgaatttc
    13021 ttgcaaaaag cttttaacaa ggcttatggc gtcgaaaaga gtcgtggact tatttcccat
    13081 cagatgctaa gtctcctagt cagttttggc ttgcagctcc tctttgcgtt tgccttgttt
    13141 ttgatcttat ttggtcagat gattttggct ttacttgctc attattggac aaaagatggc
    13201 attatctatc aggctttaca agggttggca ggtcctctga tttacgccct cctctttgct
    13261 atcttggtca tgctttatta ttttcttccc aatctatcta acaggaaaat tagctatacc
    13321 ctaccaggca gtgcctttgt tctcttagtg attttaggtt tactaactct gttctctagt
    13381 tatctcaatt actatgtcca tcatttggtg gatgtccgaa ttttaggttc cgttcttctt
    13441 gttgttatga tgttttggtt tatcttgatt gctaaaattg ttatcctagg cgcggttatc
    13501 aatgccagta tgcagagttt gaaagatccg gtctttaaaa aagactaact atttatccat
    13561 tataaaagcg catagtatca agactttata gaaccttgat actatgcgct tttgtgcttt
    13621 gacagttttt tgtatagttt ttgtccaaga tttctaaatc atctgattaa attcctattt
    13681 tcccctatca ttgtccctgt tttttcgaaa atggaaggag tataataaat ctatcaataa
    13741 aatgatagga ggaactttat gggtcatatt ttcttttttc taagtgtctt tttggcaggg
    13801 attctatcct tcttttctcc ttgtatctta cctttgttac cggtctatac aggggtgtta
    13861 ctagatgata aggatggtgc tcaggcttct agcggcaaat tttcaatctc agttactagt
    13921 ttattacgaa ctctggcctt tatagcagga atttccttta tatttatttt gttgggctat
    13981 ggagctggtt ttttaggcga tttgctttat gcttcttggt tccaatatct tactggggca
    14041 attattatcc ttcttggttt gcaccaaatg gagattctac actttaaggg gctttataag
    14101 gaaaagaggc tacaactgca aggacagggg caaaatggta agggctatag tcaggcattt
    14161 ttattgggct tgacctttag ttttgcttgg acgccttgcg tggggccggt tctagggtct
    14221 gttttggcct tggcggcttc aggtggttca ggagcttggc agggagctgg tctcatgttg
    14281 gtgtatacgc tgggcttggc gctaccattc ttgcttctag ctctgacctc tagttatgtt
    14341 ttgaaacatt tccgaaaact tcatccctat ctcggaatcc tcaaaaaagt gggaggtttt
    14401 ctcattattg tgatgggact cttggttctg tttggaaatg cttcaatttt aagtcaatta
    14461 tttgaataaa atggaaagga atatcaatat gaaaaaatgg caaacatgtg ttcttggagc
    14521 gggttcgctc ctttgtttga cggcttgttc aggcaagtcc gtgactagtg aacaccaaac
    14581 gaaagatgaa atgaagacgg agcagacagc tagtaaaaca agcgcagcta aagggaaaga
    14641 ggtggctgat tttgaattga tgggagtaga tggcaagacc taccgtttat ctgattacaa
    14701 gggcaagaaa gtctatctca aattctgggc ttcttggtgt tccatctgtc tggctagtct
    14761 tccagatacg gatgagattg ctaaagaagc tggtgatgac tatgtggtct tgacagtagt
    14821 gtcaccagga cataagggag agcaatctga agcggacttt aagaattggt ataagggatt
    14881 ggattataaa aatctcccag tcctagttga cccatcaggc aaacttttgg aaacttatgg
    14941 tgtccgttct tacccaaccc aagcctttat agacaaagaa ggcaagctgg tcaaaacaca
    15001 tccaggattc atggaaaaag atgcaatttt gcaaactttg aaggaattag cctaggaggt
    15061 gtctcatgaa tgataagtta aaaatcttct tgttgctagg agtatttttt ctagccataa
    15121 ccggtttcta tgttctattg atacgaaatg cagggcagac agatgcctcg caaattgaaa
    15181 aggcggcagt tagccaagga ggaaaagcag tgaaaaaaac agaaattagt aaagacgcag
    15241 acttgcacga aatttatcta gctggaggtt gtttctgggg agtggaggaa tatttctcac
    15301 gcgttcccgg ggtgacggat gccgtttcag gctatgcaaa tggtagagga gaaacaacca
    15361 agtacgaatt gattaaccaa acaggtcatg cagaaaccgt ccatgtcacc tatgatgcca
    15421 agcaaatttc tctcaaggaa atcctgcttc actatttccg cattatcaat ccaaccagca
    15481 aaaataaaca aggaaatgat gtgggaaccc agtaccgtac tggtgtttat tacacagatg
    15541 acaaggattt ggaggtgatt aaccaagtct ttgatgaggt ggctaagaaa tacgatcaac
    15601 ctctagcagt tgaaaaggaa aacttgaaga attttgtggt ggctgaggat taccaccaag
    15661 actatctcaa gaaaaatcca aatggctact gccatatcaa tgttaatcag gcggcctatc
    15721 ctgtcattga tgccagcaaa tatccaaaac caagtgatga ggaattgaaa aagaccctgt
    15781 cacctgagga gtatgcagtt acccaggaaa atcaaacaga acgagctttc tcaaaccgtt
    15841 actgggataa atttgaatcc ggtatctatg tggatatagc aactggggaa cctctctttt
    15901 catcaaagga caagtttgag tctggttgtg gctggcctag ttttacccaa cccatcagtc
    15961 cagatgttgt cacctacaag gaagataagt cctacaatat gacgcgtatg gaagtgcgga
    16021 gccgggtagg agattctcac cttggccatg tctttacgga tggtccacag gacaagggcg
    16081 gcttacgtta ctgtatcaat agcctctcta tccgctttat tcccaaagac caaatggaag
    16141 aaaaaggcta cgcttattta ctagattatg ttaattaata ctcttcgaaa atctcttcaa
    16201 accacgtcag cgtcgtctta ccgtatgtag ggtt
//
LOCUS       DAVDHZ010000048        15478 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000048 DAVDHZ010000000
VERSION     DAVDHZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.049"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(53..1219)
                     /locus_tag="VUR46_001844"
     CDS             complement(53..1219)
                     /locus_tag="VUR46_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5457211.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VELYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            complement(1227..2321)
                     /locus_tag="VUR46_001845"
     CDS             complement(1227..2321)
                     /locus_tag="VUR46_001845"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET5457212.1"
                     /translation="MSKELHLNTILAQAGIKSDDATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAVIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVVFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRYS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(2479..3921)
                     /locus_tag="VUR46_001846"
     CDS             complement(2479..3921)
                     /locus_tag="VUR46_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457213.1"
                     /translation="MRKKVIEGLIYAEKSFFDKNQSGELTSAIVNDTSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVYSRSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITFSISKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGQSQRLQIARA
                     YLKDTEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFVLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(3927..4160)
                     /locus_tag="VUR46_001847"
     CDS             complement(3927..4160)
                     /locus_tag="VUR46_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HET5457214.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            complement(4332..6290)
                     /locus_tag="VUR46_001848"
     CDS             complement(4332..6290)
                     /locus_tag="VUR46_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5457215.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTGRLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDILSVKSGGMLQNFGLEPGEVNEKAKAVGLDTYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAGAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(6492..8114)
                     /locus_tag="VUR46_001849"
     CDS             complement(6492..8114)
                     /locus_tag="VUR46_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET5457216.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGTY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLILIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYIKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMGLFVFTVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            8220..9659
                     /locus_tag="VUR46_001850"
     CDS             8220..9659
                     /locus_tag="VUR46_001850"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET5457217.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNSVVFDTICYDSRKAK
                     EKSLFFVKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAMEFY
                     GNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALTTP
                     ESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIEHP
                     SFEDYFYHKRLLMENSRAVIINSDMEHFSVLKEQAEDQDHDFYGSQFDNQIENSKAFS
                     FSATGKLAGDYDIQLIGHFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEVLT
                     QKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLNQH
                     PEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAVII
                     AGKGADCYQIIQGRKESYPGDTAVAENYL"
     gene            complement(9702..9899)
                     /locus_tag="VUR46_001851"
     CDS             complement(9702..9899)
                     /locus_tag="VUR46_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET5457218.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(10000..10608)
                     /locus_tag="VUR46_001852"
     CDS             complement(10000..10608)
                     /locus_tag="VUR46_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HET5457219.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFSMLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            complement(10633..11145)
                     /locus_tag="VUR46_001853"
     CDS             complement(10633..11145)
                     /locus_tag="VUR46_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET5457220.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPAAFFESNHLYDLYVYPEMDIQSVKERACKHFGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(11232..12167)
                     /locus_tag="VUR46_001854"
     CDS             complement(11232..12167)
                     /locus_tag="VUR46_001854"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET5457221.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELVELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(12238..12537)
                     /locus_tag="VUR46_001855"
     CDS             complement(12238..12537)
                     /locus_tag="VUR46_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET5457222.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(12527..13276)
                     /locus_tag="VUR46_001856"
     CDS             complement(12527..13276)
                     /locus_tag="VUR46_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET5457223.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(13331..13690)
                     /locus_tag="VUR46_001857"
     CDS             complement(13331..13690)
                     /locus_tag="VUR46_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET5457224.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(13692..15092)
                     /locus_tag="VUR46_001858"
     CDS             complement(13692..15092)
                     /locus_tag="VUR46_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET5457225.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYM
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            15273..>15478
                     /locus_tag="VUR46_001859"
     CDS             15273..>15478
                     /locus_tag="VUR46_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5457226.1"
                     /translation="MQILDIIKKDTHKEIIAKLDYDAPSCPECGNQLKKYDFQKPSKI
                     PYLETTGMPTRILLRKRRFKCYHCS"
BASE COUNT         4697 a         3467 c         2788 g         4526 t
ORIGIN      
        1 cgcctatgaa aatagccttc taggaagact tttctcctag aaggctggat ttttaacatt
       61 tggcaaaagt agccacaatc cgctgacaga cttcttgcaa cagagatttg ggcatagcta
      121 tattgatgcg ggcatggaga cttccttcct ctccaaaatc caaaccacgg ttgaggataa
      181 ccttggcttc atttctcaac aactcttgca atgtttcatc agtcaggtca taggctgaaa
      241 agtcaagcca aatcaagtag gtaccttgcg gtttcatgac cttgatttta gtctcttttc
      301 caaatagatc caccacataa ttgatgtggt cttcaaagac ttgcttgagt tcctctagcc
      361 aatctttacc gtatcgatag gcagcttctg tcgccaaata acccaagcct gaaatttcat
      421 gctgattatt ggccaacagg cgtttctgga aagccagtct caacttagga ttttcaatga
      481 ctgcatagga attttttgtt ccagcaatat taaatgtttt agtggcactg ctcaagacga
      541 tagcaaaatt tttgaaggca ggattgatgg tattgaaaga ctggtgtttg tgaccaaaga
      601 gggtcaaatc ttggtgaatc tcatccgaaa ctaacaaaac accgtgtttt tggcagagtt
      661 ggccaatctt ctccaacact tctttttccc aaacacgtcc accaggattg tgagggttgc
      721 aaagaatata gagttcaacc tcctcttcca ccaaatcctt ttcaagttgg tcaaagtcaa
      781 tctcaaacag accatccttt tccactaagg aattagtaat caatctacga ttattcaact
      841 tgacactgcg agcaaagggt gggtagacag gcgtgttaat taaaaccgcc tcgccttctt
      901 ttgtaaaggt ttgaatagct gttgagatgg ctggtaccac accctcgata aagacaagag
      961 cctctttgtc aaagttgtaa ccgtattgtg tagcttccca cttttgaact tccttaatta
     1021 agtcttcact ggcataggta taaccataaa ccagttggtc tgcgtaagtt tgcacggctt
     1081 ggcggatttc aggcaagacc acaaagtcca tatccgctat ccaagctggt agaacttcac
     1141 tatccgtttc tgtttctttc catttatagg tatggtgccc taaacggttg ggcaggcttg
     1201 taaaatcata ttttcccatc tttgtcttat ccttctaagg cttggcgcaa atctgcaatc
     1261 aaatctctag catcctcaat cccaatagac aaacgcaaga ggtcatctgt caaaccataa
     1321 gaatagcgta cttctgctgg aatatcagca tgagtttgag tcgttggata agtaataaga
     1381 ctttccactc cacccaaact ttccgcaaaa gagaagacct tgagactgtt caaaatatga
     1441 ggaatgcgtg tttcatcggc tactttaaag gaaatcatgc ctccacgacc agtgtagaga
     1501 acttccttaa ctgctggaga atccttcaaa aagacaacca cttcttgggc gttagctgtt
     1561 gagcgctcca tacgaagaga caaggtcttg agaccacgaa gcaactggta gctgtcaaat
     1621 ggagacaaga ctgcccctgt tgtattaaga ttgtaaaaaa gcttctcgta tagttctaaa
     1681 ctattggtca caaccactcc agccaagaca tcattgtggc ctgctagata cttggttgct
     1741 gaatggagaa cgatatctgc tccatcttca atcggacgtt ggtagatagg gctatagaag
     1801 gtattgtcca ccaccacttt ggcaccctta gcatgagcca attttgctag tttttcgata
     1861 tcaaattcca acatcaaggg attggttggg gtttcgatat agagaacatc cacatccttt
     1921 tctaactcgg caatcaactc ttcttctgta ttggcatagg taaaatggaa acgaccttcc
     1981 tgctccactt ggttaaacca gcgaaaagaa ccaccgtaaa gatcacgcac tgccaagacc
     2041 ttacttccta ctggaaagac gctaaaggcc agtacaatag ctgacatccc tgagctagtc
     2101 gctagggcat agtctgctga ctcaataacc gccaagactt cctcagcctt actgcgagtt
     2161 ggatttttag tacgtgtata atcaaaccca gtagatcgac caaactctgg atgctgatag
     2221 gtcgttgaaa aatgaagcgg tgtcaccaat gcacctgtcg cgtcatctga tttaataccc
     2281 gcctgggcca aaattgtgtt aaggtgtaat tccttgctca tacaatacct ccaaatctat
     2341 agtaactatt gtaccactta ttttgtatcc ttcgttttct tgttttcaag agctagttat
     2401 agtttcaaac tatataaaaa gggagctttt cctgctccct ttaatagact ataaaatggt
     2461 gaatctcaaa agacaccttc actctatcat ttgctcctgc acaaaacgag cataacgctc
     2521 atgattttct agtaattcct tatgagttcc tgagccagtg attttcccct cctctaagac
     2581 gaaaatacaa tccacatctt ttaccgttga caaacgatgc gctataatca caaccgtctt
     2641 ctcctttagc acagaataga ggctactgat aatcgcatac tcagaatccg catcaagatt
     2701 agcagtggct tcatcaaata taagaatttc agtatctttt aagtaggctc tagctatttg
     2761 aagtctttgg ctttgtcccc ctgacaagag tcgtccgcgt tcaccaactt cagtatctag
     2821 tccctctttc atggagcgaa tctcatcacc tagtgatact aagtctagca ctttcatcaa
     2881 ttcatcatca gttactaagc gattcaaacc gagacaaaga ttgtcacgaa tactgccaga
     2941 taagactgca ttattttgtg aaacccaagc gattttactt ctccattctt ttaagttaaa
     3001 atcatatata cttgattgct ccattagaat atctcctgaa agcggcttat aaaaccgctc
     3061 tagcaaacgc acaatcgttg attttcctga tccagatggt ccaacaaaag caattttttg
     3121 ccccttggaa attgaaaaag taatatcctt taagacaggt cgattttcat cataaccaaa
     3181 atagacatgg ttaaaattca acccttgtcc tgataccgat tttcctccct caaatttttc
     3241 tttaggaact gcaagcaagt tctccagtgc aactgaagat cccttgctcc tagaataaac
     3301 agttacaaaa ttagctatat tactaatagg attaagtaat tgaaagaggt aaatcaaaaa
     3361 cgaaaccaag gttcccacag atatatatcc tgcgctgacc cgataacccc cataggttag
     3421 catcacagct atagtcgcaa agataaataa gagagcaaac ggggtctcaa aagaagtaac
     3481 cctatctgat ttcagtgaat tgttttgtac cctttcaata caattatcca aaacatcctg
     3541 tacacttttc tctgcttggt tagtcttaat taattcatgt tcttgaatct tttcagtcaa
     3601 ttgccctgtt aaaaatccga tttcctcctg taaacgacga ctatactttt cactgatatt
     3661 ggaaaggggc aagataataa acatcataca aggaagagtg atgaataaaa gtagagaaag
     3721 attccaatca agactaaata agactacaat ggaaccaagt accataacta aactcagaat
     3781 aatatttggg aaagtcgtaa ttaaaaactc acgaatgaca ctcgtatcat tgacaatggc
     3841 agaagtcaac tccccacttt ggttcttatc aaagaaggat ttctctgcat aaatcaaccc
     3901 ctctatcact tttttcctga tttttgctat cttttttcac ccgattgact aaaaagatag
     3961 taaccaatag aagaaaacaa ggcttgacca ataaaaatca aaaacgattg aaatactttg
     4021 gaacctatat tttcaataga actcccatct attaaaccct ttaagataag gggaagcaac
     4081 aaagcaagta gactagacag aacaaggaag aaactcccca taatcacctt agtatctact
     4141 cttaataatt ttaatttcat aaatactcct tataatattt caacggataa agtcaggaat
     4201 aactcaattt gaggataaaa tctaataaat cttcctataa caaaacgcat aacatctagg
     4261 attttatata cctgatatta tgcgttttta agcacaaaga cttcttacac aaacttatct
     4321 acaattagat tttatttgac atgttttgcc aattcttctt gggctttttt attggattct
     4381 tctttttctt tcaaccattt ttctctggct tttgcatatt cgtctgttgt gacaatctta
     4441 tcttgtactt tgaggtattt atatgattca accccttttg taccggttaa accataggca
     4501 ccagcaaatg gtacggttct tctcaatgat ggggttcccc cacgcgaaac acttggaaga
     4561 actaaagaac tatcaatcaa ccaagcttga atatcagcat atttctcata acgtttggct
     4621 ggatcttgct ctttattagc ttcttccaac atttgagtat aggtatcaag cccaaccgcc
     4681 ttagcttttt cattaacttc acctggttct aaaccgaagt tttgcagcat tccgccactc
     4741 ttcacactca agatgtccag ataagttgat ggatcttggt aatcaggtcc ccaaccgcca
     4801 tgatataaat catagtcttt ctgagcagct gtttgagcaa aatagcctga actgtcaaac
     4861 tcatctgatg ttaattgctg aatgtcaatc actacattat cagaacctaa aacagattca
     4921 attgattgtt tgatagaact aactccttgt atgcctactt tatctgttac ttccacagtc
     4981 ttatccaagt ggattgggaa ttgaacaccc tttgcttcga gttctttctt agcttccgca
     5041 aacttagcct tggctttctc aggattgtag taagggtctt gaccatccgc aaagttgata
     5101 ccttgccatt ccttaccata gttgaccatc ttagaggcta caacttcacc aaagtctttt
     5161 cccttgatac tgacaaagtt tggaggaacc actaggttac gcaaaatctt tgttgcacct
     5221 tctttccctt cagactgagc cccataagat gttctgtcaa aagcaaaatt gatagcctga
     5281 cggaagtttt tattgagaac tgcttcctga gtcgatttct tttcaatgtc acttgtttta
     5341 gaagtataat tgtaagactt cctatctagg ttaaaattaa agaaatatga agttgaattt
     5401 tgcatactat agatgatatt gtttttgtat ttttctttaa tcccttcata gctggagctg
     5461 ttaggaaaaa gacgacccgt agtataagca ccagctgtaa aattacgttc cagtgattct
     5521 tggtcgctac catcatagta ggtcaatttc acatcgtcta caaagacatt cttagcatcc
     5581 cagtaattag ggtttttctt atattcaata gcagattttg agacaagtgc tttcatcaag
     5641 aaaggtccat tgtacaaaat actagatgga tccgccttcc caaaatcatc cccttttgat
     5701 ttcaggaaat ctgcattaac aggaaaaagt atcgttgcaa gtgtttttga attccagtaa
     5761 agttctggtt taaccaaagt atattgaacc gtttggtcat caagtgcctt gacaccgaca
     5821 gttgaaaagt cgcttgtttt accagtgata tagtcatcca aaccagcaac agagtcctgc
     5881 actagataca aggcttctga ttttttatca gctgcatatt gcaaacctgt cacaaaatcc
     5941 tgggcagtta caggcgcata ttcttctccc tcagaagtaa accacttggc atccttacga
     6001 agtttgtagg tataggtcaa accgtcctga gaaacagtcc aatcctctgc taatgatgga
     6061 ataatattcc catattggtc attttctaat aacccgtcta ccaaatttgc aacaatatcg
     6121 gatgttgctg cgcggttttc tgctagatag ttcaagctag atggatcact tgaataaaca
     6181 tagttgtatg tttttgacgc cgtgctagaa tttccacacg cgctcaataa aactcctgta
     6241 cccaggacaa gacctgccaa ggttagatat ttgctcttag actttttcat ttccagaacc
     6301 tcctgcttta aatatttgtt ttattataca acgtttggtt tgtttagtca attatttttt
     6361 ccaaaaaatc gaaaaaaact cattttctat ttttgaaaga taattttagc tattttgacg
     6421 ctaaaaaagg aataagttca agttctccta aaagattgtt caacttattc cttttattta
     6481 taaatgctac cttacgaaag cttaaatttt gctcgcaggc gatctgcttg ggcttttcct
     6541 attaccttat ctaataaata ggtacgcaga ctcataacca tataaagtcc accccccatg
     6601 gcaccgacaa gagctacata aaagaagctc cacaaacgtc cacttggttg gaagaaaaat
     6661 cctaacagcc actggatggt tcctattaac agaaacatga ctagggtcag caaactgatt
     6721 aaaatggttc gcttcaaaat caccttgcgc ttgacaccag ttactttaca aatatcccga
     6781 tacatcaaga cgttaggaat gatgagagca atggttgttg aaatcaaagg accataactg
     6841 tggaagaggg cgatggtagg tagttgcaag actagcttgg caatagaacc gtagataaaa
     6901 tagagaacgg ccttgcggtt gcggaacatg gcctgaagca ttggagacaa gaccatatac
     6961 aagcctaaaa taatagactg caaaactgta aagacaaata agcccatagc caaactatct
     7021 ggcttaccat agaagaccgt ataaagaggt tctcctacca taaccactcc aaccgttgct
     7081 ggtagcaaga acataaagag tagggtgaga ctgtcctgaa cgagacgaga agctgccttc
     7141 aagtccccct tgatatagtt ttccgtcaaa agtggcaaac caacactccc aatcgaaacc
     7201 cctacagaaa tcaaaatcat cgtgatttta ttaggattgg ctgagaaata agaaaacatg
     7261 acaaccaagt cctcattact gtagttggta aaccagctca tactattgat aaaggtcagc
     7321 tgatccaaaa tctgaaagag ctggatggca gaccctgtca ggataaaagg aatggcttcc
     7381 ttaatggtat caaccaagag acgcttactg ttaatcttat ctcctgtttc aaagactctt
     7441 ttgagtgaac cttcttgggc aaggaaataa atcaagactg caaaactggc taccataccg
     7501 acaaaggcag caaaggttga ttgggtaacg gctgctagat aatctcctga accgagcttc
     7561 ataatgataa aggttgctag gagcatccag ataacacgaa tgacctgctc agcaatttga
     7621 ctcatggcat aaggtttgag gttattcatc ccttggaaaa atcctcggat aacactcata
     7681 gacgggaaaa tcaagactcc ccaagccaag ctttgcatga ttaggatcaa gtctttgccc
     7741 acgccagaca agtctgctag ccaaggagca aagacataca agactaaagc aaaaaccaga
     7801 cctagtcctg tcataaagcc taagaagctc cgaatcaggg caaagctatg ctcttcttct
     7861 cgcatagtat tatacttggc aacttgcttg gccaccgcaa ctggaatccc cgctgttgaa
     7921 accaacaaga accaagcata gatattgtaa cccatggtaa agagaccatt tgccttagct
     7981 gcataagtcc ccatccagat gtaccaaggg ataatgtaaa cagccccgag taggcgactg
     8041 ataaagttac tagccgttag ccaagcagtc ccccgtaaca tctgagcctg ctggtgattg
     8101 ttttcgtgcg acatagattc ctcattcaat tttgataact aggaaaaact ccttatcttc
     8161 cattataaac ttttccttgt tacttgtaaa tttgcgactt tcggtttaca atagaaagta
     8221 tgataaaaat tgaaaccgta ttagatatat taaagaaaga tggtctcttc cgcgagatta
     8281 tcgaccaagg acactaccac tacaacagtg tcgtctttga caccatctgc tatgacagcc
     8341 gcaaggccaa agaaaagagc ctatttttcg tcaagggcgc tgcctttaaa aaagaatacc
     8401 ttctttctgc tataacacaa ggcttagctt ggtatgtagc tgaaaaggac tacgaagtcg
     8461 gtatccctgt catcattgtg aacgatataa agaaagccat gagtttgatt gccatggagt
     8521 tctatggtaa tccacaggaa aaactcaaac tccttgcctt tactggtact aagggtaaga
     8581 caacagcagc ctatttcgcc tataacatct tatctcaagg gcatcgacct gctatgttgt
     8641 cgaccatgaa cacaactctt gatggcgaga ctttctttaa gtcagcgttg acaacccctg
     8701 agagtattga cctctttgac atgatgaatc aggctgtgca aaatgaccgt acccacctca
     8761 tcatggaagt ctccagtcaa gcctatctgg tcaaacgtgt ctatggtcta acctttgatg
     8821 tgggagtttt cctcaatatc agcccagacc atatcggccc gattgaacac cctagctttg
     8881 aagactattt ctaccacaag cgtctcttga tggaaaatag ccgagcagtc atcattaaca
     8941 gtgacatgga gcacttctca gtcttgaaag aacaggctga agatcaagac catgatttct
     9001 atggtagcca atttgataac caaatcgaga attccaaagc ctttagcttt tcagctacgg
     9061 gtaaactcgc tggagattat gatatccaac tgattggtca cttcaaccaa gaaaatgcag
     9121 ttgctgctgg acttgcttgt ctccgtctcg gagcaagtct tgaggacatc aaaaaaggca
     9181 tcgctgcaac ccgcgttcct ggtcgtatgg aagtcctcac tcagaaaaat ggagccaagg
     9241 tcttcatcga ctatgcccac aatggggata gtctgaaaaa actcatcaat gtggttgaaa
     9301 ctcatcaaac cggaaagatt gctctggttc tgggatcaac aggaaacaag ggagaaagtc
     9361 gtcgtaagga ctttggcctc ctcctcaatc aacaccctga gattcaagtc tttctgactg
     9421 ctgatgaccc taactatgaa gacccaatgg ccattgcaga tgaaattagt agctacatca
     9481 atcatcctgt tgaaaagatt gcggatcgcc aagaagccat caaggcggca atggctatca
     9541 caaatcacga attagatgca gttattattg cgggtaaggg agccgattgt taccaaatca
     9601 tccagggcag gaaagaatcc tacccaggag atacagccgt cgcagaaaat tatttataag
     9661 aatagaaaaa atcaagggaa aatgaaaccc ttgatttttt cctattcttt agtaaaaacg
     9721 tttttcaaac cttcaacggc accttctaca gcaccttttg cgtcttctac aacgtctttt
     9781 gccttagcaa ctgttttttc aacagctcct tcaagttctg tcttgctgtc tccagtaact
     9841 ttaccaaaac cttctttgac agcgcctgtt gcttgttcca atttgttttc aagtgacata
     9901 tgattgtctc ctttagttta ttccgatatg tgttaccggt tacatatagt ttataccgaa
     9961 tactaaggaa agtcaaacaa tgtgctcaga aacaagaaat cacgctaagt agaaagttaa
    10021 tctctcctta tcaaaatcga tagccaactc atactttcca tcttcatttt gcacaatata
    10081 gcctaagaca accaaactgt ccacaaagat atcacggcat ttctgcataa gctggtcttt
    10141 tttgagaaat ttcaacaaaa aagccgtcat atacttgagg gcatactcag gattaacatc
    10201 tcctaaaatg tcatagagct cctgctgttt ttctgtcaaa ggatactgct gtttgacctt
    10261 gtaaaaataa ttggacaggg tcattttaat gcgcgcaaag tccgtctttt caactaaaat
    10321 agctgcattg atttgattgc gcaattccgt ctcaaaactc tgctccaaca aggcttgata
    10381 gaccggacta gcttctctga caaaaatctc ttgatccagt tcaagactat caagtgattc
    10441 aagcatagaa aaattgaggt aatagcgttt attttcacgt agaatcaagc ctgcctttat
    10501 atactcttcc atgagtttat caactgcaac atctggaaat tgagccttaa tttcccgtag
    10561 aatcacatcc tcatactggt ccagatatcg gatcaattct ccaaaaatgg ctgtctcgtc
    10621 aaacgagatg gattaaaaat ctgaatcatg aagattcctt tctttacatt gtaacagagg
    10681 cgatgctgcc aactgactag gattggtacc agcttggttc agaggaacag gcagacctag
    10741 ttctatgtaa tactccctcc aaaaatcact aatctcctgc tccccatctc caaatttcat
    10801 aggaatagtt tcaaaaatag gtaggatttc tgctatatac tgggagcagt agaaaccagc
    10861 tgcatctgga tagaaagaag cattgtaggg tgctccaaaa tgtttgcaag ctctttcctt
    10921 caccgactgg atatccattt ctgggtaaac atagaggtcg tacaaatgat tggactcaaa
    10981 gaaggctgcc ggttcttgac agacaacacc agcctgtcca ctagcatgat aaatcatccc
    11041 atccaaataa atggcaacat ggctatagtt acctgtggaa gtctggatgg cctgtcccat
    11101 gtctgaccca tctctcacaa aaatcaaatc accattttct aacatacttc actcctagaa
    11161 aaaaaggagc cgaaactcct ttcgatataa ggcaaactag cctttccgat tttgagctga
    11221 cacccaaaat cttacgcatt aaagctttca gtcaattgag gtaccacttg tttcttacgt
    11281 gaaacggcac cagcaaggaa ggcatgattg ttttcaagtt tgaagttgaa agccgcttcg
    11341 accttgtcca tattggcacc aagagccaag atttctgagt ttgagttgac gatatctgta
    11401 atcatcaaga caaagtcaga gtagccgttt gattcgttgg cagcttgcat tgcagcttca
    11461 atttctgctt ggcgttccaa aacttcagcg atgtcaactg tgttcacttg ggcaacacgg
    11521 acattatttc cgttgagttc aaaagtctta gcatcgatgt caatcaattc ttcagcagat
    11581 ttgctagcca agttggtacc agctttcaac attgccaaac catattcttc caagttcaca
    11641 ccagccaatt caaccaattc aggagcaatg attttatctg ttgggtgtgt tgttggtgat
    11701 ttcaaaagaa gggtatctga aatcaaacct gaaagcatca aacctgcaat ctctttaggc
    11761 acagctacac catgttcttt gaacatacgg taaacgattg aagacgctga tccaactggc
    11821 tccaaacgca tgtaaagtgg gcttgcagtt tcaaagttag ccacacggtg gtggtctaca
    11881 acaccgtaaa cttctacttc agcgatatct gatacagatt gttggaattc attgtggtca
    11941 gtcaagataa cttgctctgc cccctctgct ttggcagaag tgataacacg tggtgcttcc
    12001 acaccaaaat agttcaagac aaaggctgtt tcttcatttg gagttccaag ggcaacagct
    12061 tccgtatcca aaccgtaagc ttcttttgca aggtaggcaa aagctacaga tgacccgatg
    12121 gcatctgagt ctggattttg gtgaccaaat actagaatct tggacatggt aatacctcat
    12181 tttgtttatt ttctttattg tagcattttt ttcgcttttt gacaaaggta agaggagtca
    12241 aaggactccc cacgattctt caaaataact gagtaaattt ctatcttgat tttcagataa
    12301 aaattcttcc ttctgtggcc tcttcttacg cttgagaaga gcctcagccg acatggcttc
    12361 ttccttactg gcaaaacctt gagcatagat aagtttgact ggcaagcgtg ctcgtgtata
    12421 tttggctccc ttcccactat tgtggatagc gaggcgtctt ctcacatcag tcgtatagcc
    12481 tatatagtag gatccatcac gacactccag aacgtacata taagccttat gatccataat
    12541 aaatctcttc gatttcgggc gtataagagc catcatcatt gtggacaatc aaaggaggta
    12601 agaccttaaa gccacttgtt gagccatcct tgatcgcctc aatcaaaagc atattggctt
    12661 ccttttctct ttttggataa acaaactgca ggcgcttagg ggctagatta tgtcgtttta
    12721 acgtatccaa aatatccaga agtcgatcag gacgatgaac catggccaaa cgcccattag
    12781 acttgagaat actctgggca ctacgacaga tttcttccaa attagtcgtg atttcgtgtc
    12841 gagccaagag ataatgttca ctctcgttca gattagaata aggatccacc ttgaaatatg
    12901 gtggattaca caaaatcata tccaccttac tcccctgaat gtgagcaggc atatttttca
    12961 aatcatcgca gatgacctgc atttgctcct ctaatccatt caaacggaca gagcgttcag
    13021 ccatatccgc caaacgctcc tgaatctcaa cagacaatat ctgtgcttga gtacgagtgc
    13081 tagcaaaaag ccccactgct ccattcccag cacagaaatc cacaatcaac cccttcttag
    13141 gaaaacgtgg aaatcgtgat aagagaacac tatccaccga atagctaaaa acctctctat
    13201 tttgaatgat tttgatatct gtcgaaaaga gctggttaat gcgctctcct gattttaata
    13261 attgttcttc ttccatggtc ctattataat aaatttatat taacattaca aaaaaatata
    13321 aaactctaaa ctacttcttc ttttttaaat ggtgcagagc ttctccagtc cagattggta
    13381 gcattcgtcg aaagggagca aaaccgtagt taaagcggtc gcttgaaaag cgtctccgtc
    13441 taggaaactg gtacttttct tcctccaaag tgcggataga aagactggct ttccccgtaa
    13501 attcatctaa atccactacc tgaacttgaa cctcttcatc gactttcaag gtttcatgaa
    13561 tattttcaat aaatcctgtc cgaatttctg aaatgtgaat cagccccgta tcacccgtct
    13621 ctaactcaac aaaggcaccg tagggctgaa tccctgtaat acgccccttt agcttatcac
    13681 cgattttcat cttagtcctc gatttcaata gtttcaatta caacatcttc aactggcttg
    13741 tccatagctc ctgtctcaac agcagcaatg gcatccaaga cagcgtaaga tgcttcatca
    13801 gctaactgac caaaaaccgt gtgacggcgg tctaggtgag gtgtcccacc ttgattggca
    13861 tagatttctg caatcggttc tggccaacca ccacgagtaa tttctttctt cgaataaggt
    13921 aggtgttggt tttgcacgat aaagaactgg ctgccgttgg tatttggacc agcatttgcc
    13981 atggaaagag caccacggat attgtaaagc tcttctgaga attcatcctc aaaagattcg
    14041 ccgtagattg actcgccacc cataccagtt ccagttgggt ctccaccttg gatcataaag
    14101 tccttgataa tacggtggaa aatgacacca tcatagtagc catcttttga aagagataca
    14161 aagttagcca ctgttttagg agcatgttca gggaaaagct tgatacgtaa gtctccgtga
    14221 ttggtcttaa tagtcgcaag aggaccttct actgtttcaa tgtctacttg tggaaaatgc
    14281 aattcttttt ctaccatacc aaatacttct aaggcatcaa aaatgccatc ttcttctaat
    14341 gtttttgtaa tataatctgc tttttctttg attttatcat gagaaattcc catggcaacg
    14401 ctgattccag cataatcaaa gagttccaag tcattgagac catctccaaa aaccatgacc
    14461 ttctctggtt tcaagccaag gtgttccaca accttttcca cccccgtcgc tttggagcct
    14521 gaaatcggca caatatcaga cgaatgttga tgccaacgaa ccatgcgaag tttgtctgag
    14581 agactgtcag gcaagtgcaa gtcatctccc ttatcttcaa aagtccacat ctgatagata
    14641 tcttcttttt catggaaatc gggatctaca tctaagtcgg gataaattgg attgatagct
    14701 tcactcatca tatcggtgcg agtcgacaac ttggcatcat gactcccaac caagccatac
    14761 tcaattcctt cttgcttagc ccaagacata tactcctcaa catctgactt ttcaatctga
    14821 tgctgataaa tgacctgacc ttttttatct tcgatataag ccccattcaa agttacaaaa
    14881 aagtcaggct tgagatcacg aatctctgga acaacaccaa aaatgccacg tccagaggcg
    14941 attcctgtta aaattccttt ttcacgcaac tgtttaaaaa cagtgggaat tgtagttgga
    15001 ataaaccctg tctttgaatt ccgcaatgta tcatcaatat caaaaaagac aatcttgatc
    15061 ttctttgcct tgtatcttaa tttcgcgtcc atctcactac ctctttcaat ctaactcttt
    15121 ccattatatc ataaagtagg caaatcccct attttcaaaa agtttatcat ttttatttta
    15181 atttcttgga tgagaaaaga gacatattta tgaaaaagtc caaccaaatt caactcgact
    15241 tctcattcca gaactcgtaa aaaaaaccta atatccagat tttagacatc atcaagaagg
    15301 atacacacaa ggaaatcatc gccaaactgg actacgacgc cccatcttgc cctgagtgtg
    15361 gaaaccaatt gaagaaatat gactttcaaa aaccttctaa aattccttat cttgaaacga
    15421 ctggtatgcc tactagaatt ctccttagaa agcgtcgttt caagtgttat cactgttc
//
LOCUS       DAVDHZ010000049        15317 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000049 DAVDHZ010000000
VERSION     DAVDHZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15317
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.050"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..230)
                     /locus_tag="VUR46_001860"
     CDS             complement(<1..230)
                     /locus_tag="VUR46_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="catalyzes the transamination of the aromatic amino
                     acid forming a ketoacid; first step in aromatic amino acid
                     degradation in lactococci; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5457227.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAA"
     gene            379..1389
                     /locus_tag="VUR46_001861"
     CDS             379..1389
                     /locus_tag="VUR46_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET5457228.1"
                     /translation="MSFLSKNGAGIFVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(1502..1582)
                     /locus_tag="VUR46_001862"
                     /pseudo
     CDS             complement(1502..1582)
                     /locus_tag="VUR46_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1617..2054)
                     /locus_tag="VUR46_001863"
     CDS             complement(1617..2054)
                     /locus_tag="VUR46_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET5457229.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(2139..4772)
                     /gene="polA"
                     /locus_tag="VUR46_001864"
     CDS             complement(2139..4772)
                     /gene="polA"
                     /locus_tag="VUR46_001864"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET5457230.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDY
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYGGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            complement(5275..5496)
                     /locus_tag="VUR46_001865"
     CDS             complement(5275..5496)
                     /locus_tag="VUR46_001865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457231.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGIEQGREEGLEEGLKVGL
                     VNLVRQGLLTPEVASEQLGMTVAEFESLL"
     gene            complement(5489..5605)
                     /locus_tag="VUR46_001866"
     CDS             complement(5489..5605)
                     /locus_tag="VUR46_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET5457232.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(5820..6173)
                     /locus_tag="VUR46_001867"
     CDS             complement(5820..6173)
                     /locus_tag="VUR46_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET5457233.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            complement(6291..7259)
                     /locus_tag="VUR46_001868"
     CDS             complement(6291..7259)
                     /locus_tag="VUR46_001868"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET5457234.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(7404..8219)
                     /locus_tag="VUR46_001869"
     CDS             complement(7404..8219)
                     /locus_tag="VUR46_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET5457235.1"
                     /translation="MKKNSILFIFILLLCIGLQYETIYYTDGSISGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKNALILSLLGGMFLSGWLSSFANTYIHDLLGGLFPD
                     SAFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGTASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKIGKKQGLI
                     FLGLALGTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(8244..8741)
                     /locus_tag="VUR46_001870"
     CDS             complement(8244..8741)
                     /locus_tag="VUR46_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET5457236.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENGPF
                     QEYLKEELGVDMSDQDFLPFQDIEESVREDMKLLIESSLIPDDVIISGAIYDVDTGSM
                     TVVEL"
     gene            complement(8814..10178)
                     /gene="radA"
                     /locus_tag="VUR46_001871"
     CDS             complement(8814..10178)
                     /gene="radA"
                     /locus_tag="VUR46_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET5457237.1"
                     /translation="MIAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEIEVAEVK
                     NARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGK
                     STLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEV
                     ERIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKE
                     GTLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLN
                     PSQVFLEERLDGATGSSIVVTMEGMRSILAEVQALVTPTMFGNAKRTTTGLDFNRASL
                     IMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVG
                     ELGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITPPKEIQVIGVTTIQEVLK
                     KVFA"
     gene            complement(10189..10704)
                     /locus_tag="VUR46_001872"
     CDS             complement(10189..10704)
                     /locus_tag="VUR46_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5457238.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSDMGRQQVQKLSK
                     NPLLSSAEIIVSSAVARALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENRGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(10706..11149)
                     /locus_tag="VUR46_001873"
     CDS             complement(10706..11149)
                     /locus_tag="VUR46_001873"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET5457239.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(11206..11303)
                     /gene="ffs"
                     /locus_tag="VUR46_001874"
     ncRNA           complement(11206..11303)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VUR46_001874"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(11336..11803)
                     /locus_tag="VUR46_001875"
     CDS             complement(11336..11803)
                     /locus_tag="VUR46_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET5457240.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCILFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK"
     gene            complement(12004..13290)
                     /locus_tag="VUR46_001876"
     CDS             complement(12004..13290)
                     /locus_tag="VUR46_001876"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET5457241.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKEIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(13521..13757)
                     /locus_tag="VUR46_001877"
     CDS             complement(13521..13757)
                     /locus_tag="VUR46_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET5457242.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            14023..14834
                     /locus_tag="VUR46_001878"
                     /pseudo
     CDS             14023..14834
                     /locus_tag="VUR46_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000530076.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(14869..15078)
                     /locus_tag="VUR46_001879"
                     /pseudo
     CDS             complement(14869..15078)
                     /locus_tag="VUR46_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15244..15317)
                     /locus_tag="VUR46_001880"
     tRNA            complement(15244..15317)
                     /locus_tag="VUR46_001880"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15281..15283),aa:Asn,seq:gtt)
BASE COUNT         4666 a         3749 c         2552 g         4350 t
ORIGIN      
        1 ctggctgcct gacgtagagt cagcagacca ctcatccctg tatagtagga ttggttctga
       61 tcaatcgctc gcttggccgc ctccttgaca tggtctggcg ttgtaaaatc aggttccccc
      121 aaggtcaaac gcaagacccc aggaatctcc gaaataacct ggtcaaactg acgaatcaac
      181 gaaacttgaa ttttatctaa ctgtttatta aagcgcttag ttaagtccat agatacctcc
      241 tactttcaaa acgtatctct attatactac aaaagccccc cgaccgcaaa aatacattag
      301 agaatagctt tccactttct attttacttt tcctgtttac aggtctataa tggtaacaga
      361 ttctatttgg aggtttttat gtcatttcta tcaaaaaatg gagcaggcat ctttgtctgc
      421 cttctcattt ctatcgtatc ttggtactta ggaggattct tccctgttat tggcgcaccc
      481 gtttttgcga tttttatggg catgctccta catccctttc tctcgtctta taaacaactg
      541 gatgttggat tgacctttag ttccaagaaa ttgctccagt atgccgttat cttacttggt
      601 tttggtctca atatctctca agtcttcgca gttgggcaat cttcactccc tgtcatcctt
      661 tccaccattt caatagcctt gattgttgcc tacctcttcc agcgcttctt tgccctggat
      721 acaaaactgg ctaccttgat tggagtaggt tcttctatct gtgggggttc tgccattgca
      781 gcgacagcgc ctgttatcca tgctaaggaa aaggaagtag cccaagccat ctccgttatc
      841 tttttcttca atgtcttggc tgcgctcatc tttccaaccc tcggcacctg gcttcatcta
      901 tccaatgacg gcttcgccct ctttgcagga actgcggtca atgatacttc ctctgtaacc
      961 gccacagcta gcgcttggga cagtctctac cagaccaata ccctcgaatc cgcaaccatt
     1021 gtcaaactca cgcgcaccct agctatcatc cccatcactc tctttctctc ctactggcaa
     1081 agtcgcgagc aaaaaaataa gcaaggctta caactgaaaa aagtcttccc actttttatc
     1141 ctttacttca tccttgcatc gctcctaacc acccttctga cctctctcgg tgtgtctagt
     1201 agtttcttta cccctctcaa acaactctct aaattcctca ttatcatggc catgagtgcc
     1261 atcggtctca aaactaatct ggtcgctatg gtcaaatcca gtggaaaatc cattgttctc
     1321 ggagccgtct gctggattgc catcatcctc accagccttg gtatgcagac ccttatcggc
     1381 attttctaat actcttcgaa aatctcttca aaccacgtca acgtcgcctt gccgtatata
     1441 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaacg gtgttttgag ctgacttcgt
     1501 cagtcgtatc tacaacctca aaacagtgtt ttgagcagcc cgcggctagt ttcctagttt
     1561 gctctttgat tttcattgag tataacacaa aaggtagccc atcagctacc tttttcttat
     1621 gcttcctcaa tcaagcgagt atgttctctc ttgatacagc gattcatcac gatatcatca
     1681 catccaccat cacgcaaaat ctctttcgct tctaaacttt caagtcctag ctgtgcccaa
     1741 aaaatcttgg catcagcttt gagaaaatca cgcgccacat cgggcagaaa ttcactgcga
     1801 cgataaacat tgacaatatc tacaggaaaa ggaatttcag cgaggctagc ataagccttt
     1861 tcacccaaga tttcgccacc tgccgccttg ggattgactg ggatgatttt atagccccga
     1921 gcctgcattt cctttgtcac tcgattgctg gttgtttctt cacggtcaga caaacccacc
     1981 acagcaaggg ttttactcgt tgcgagatac tgacgtatca cgccatcact tggattgata
     2041 aattcttgac tcatagaaat cctccttttt catcagtata gcacattttg aaaaggtttg
     2101 cagaattcta ctacaaaaaa ggaggactag cccccttttt atttagcctc gtaccaggtt
     2161 gctccttcat tctcatctgc gataagagga acactgagtt gaatggcttc ttccatggtt
     2221 tgtttcacca attttttcat ctctaccaat tcagatttag gcacttcaag gacgatttca
     2281 tcgtgcactt gtaacagcat cttagtctga taaccacctg caaccaaggc tttatccagc
     2341 tgaatcatgg caatcttgag aatatctgct gccgaaccct ggataggtga gttgatagca
     2401 gttcgctccg caaaaccacg aatattgaag ttgcgcgaat tgatatctgg caactcacgg
     2461 cgacgcttaa agagggtctc tacatagccc ttatcacgcg cctcccgcac cacttcatcc
     2521 atgtagtttt taatacctgg aaaacgttca aagtaggtat caatgtaggc tttggcttcc
     2581 ttacgactaa ttcccaaatt attagacaag ccaaagtctg aaatcccata aaccactcca
     2641 aagttaactg ccttggcatt gcgacggtca tttgcagtca cattatcagg acgctcaatg
     2701 ccaaagaccc gcatggctgt cgaagtatgg atatctgccc cctcttggaa ggccttaatc
     2761 aagtgctcat ccttagaaat atgcgccaaa acgcgcaatt caatctgtga atagtcagag
     2821 ctgagtagca cactatcctc ccactctggc acaaaagcct tccgaatcaa gcgcccttgt
     2881 tccaatcggg caggaatatt ttgcaagttt ggatccacac tagacaaacg cccggtctgg
     2941 gtcaaatcct gcatatagcg agtatgaatc tttccatcag ccaaaatcca gtcctgcaag
     3001 ccaattacat aagtagattg aatcttagca atttgacggt aatccaggat tttcttaaca
     3061 atcggagcaa taggagcgag acgctccaac acatccactg ctgtcgaata acctgtcttg
     3121 gttttcttag tgtattctag aggaagtccc aatttctcaa agagaagcac gcccaactgc
     3181 ttaggcgagt tgacattaaa ctcctcacca gccagctcgt aaatctcttg agtcagtttt
     3241 tcaatgacaa gctcattttc agcctgcatc tcaagcaagg tctctttctt gaccacaatc
     3301 ccagcaattt ccatcttggc aagaacaaaa gccagaggtt gctccatatc ataaagaagc
     3361 tctaattgcc cattttcgct gagtttttca agtaaaatag gctctgtttc taccaaaaca
     3421 gcaagtttac aagctaagtg ttccaagaat ttctcacgtt caggaatggc ctttttaaca
     3481 cccttaccgt agaaagtttc atcatcaacc aagtaagtct gaccataaag actagcgatg
     3541 gtcgcaattt cattgtcctc cacagtcgaa aggaggtatt tagccaaacg gatgtcaaaa
     3601 gcaggcgcct gcaaatccac accaaaacgt tgcaaaagaa ctttaacctt cttaaagtca
     3661 taaactctca gagatgtttt ttctaagaaa tccttgaaaa tcgggtcttg caacagctca
     3721 agcttgtctg tggcatagag cttatcccca caagaccagg caaatccaac caaattatcc
     3781 gtatggtaat tctcaccaaa aagctcaaag tggaagatag actcttcact cagcatatct
     3841 tgactgattt ggtcaacaat agtaaaatcc aaaccctcag ccacatcagc tgacgacaca
     3901 tttaaagcct gcttgagctg tttgaatccc atctcatcgt aaaatttccc aagattttca
     3961 acatctggac caccatagac caagtcctct aaaccaatcg caatcggtgc cttggtatca
     4021 atggtcgcta gtgttttaga caaaaaggcc tgttccttgt cattgatgag attttccttc
     4081 atcttagaag tcttcattcc atcaatattt tcataaatcc cctcaagcga accatgctcc
     4141 agcaagagct taatacccgt cttttcaccg actttggtca ccccagggat attatccgac
     4201 ttatcaccca tgagcgcctt gagatcgata aactgagctg gtgtgaggcc catttcttcc
     4261 atgaggtaat ctggcgtaaa ggcctcaaac tcagccacac ctttcttgga aatttcaacc
     4321 accgtatgct catccgtcag ctgaatcaaa tccttgtccc cactgacaat ggtaatatca
     4381 aaaccatcct gctctgctag cttatccagc gtcccaatga tgtcatccgc ctcatactga
     4441 gccagctcat agtgacgaat ccccatataa tccagcaact cacgaatgaa aggaaattgc
     4501 tcacgaaact catcaggagt cttggcccga ccacccttat agtccgcata catctctgtc
     4561 cggaaggtcg tctttcccgc atcaaaagcc accaaaatat gactcggctc aacccgctcc
     4621 aacaaatgac tcaacatcaa ctgaaaacca taaatcgcat tggtatgcaa accagccgca
     4681 ttcttaaaac ggtccaactg ctgatacagc gcaaaaaacg cccgaaaagc tacagaagac
     4741 ccatcaatca ataataattt tttcttatcc atacacccat tataaaggaa agaatcaaaa
     4801 aataccattg ggaagagcta gagcaagtat ttttcaaact ttttccgaat aaatagatag
     4861 agccagagaa tttagtaaac ctagatttaa aaatgtgcta taatatagta tattgaatct
     4921 ataatagtac accttgactg ctaaaatatt tctataaatt aatttgactt tcctgataga
     4981 gttattcaca tcttatttca actcactata gaaggaggaa aaggagggct gggtggctaa
     5041 cttcattata gaactttcaa aaagatgaaa aaatagcgtc aaagaggctt ttttctcttt
     5101 aaaacaggaa atctcaaaga caatcttgcg actatccaaa ctgtacgaat aacgagacat
     5161 aacttacttc gctaatacta tcttataaaa agatagaaat gtcaagcaaa aatgacaagt
     5221 attttgataa tagacttgcc atcccatcaa ctttctacta tataaagtat gaactcatag
     5281 caaggactca aactcagcca cggtcatgcc taattgctca ctcgcaacct caggtgttag
     5341 aagaccttga cgtactagat ttactaaacc tacttttaat ccctcttcaa ggccttcttc
     5401 tcgtccttgt tcaatacctt cagccctagc ggtttccaag gcatagtcct gtgctaacaa
     5461 gacttgttct tctcgcatat gtagttgact aaacattttc ctgtcctcct cggaccagct
     5521 cttgtagtcc agcagttgat ttgcttgggt aatggctcgt tgcggttgct gggtaaaggg
     5581 cttgttgccg aaaaactcca accatggctt gcgaaccttg tctttgctgg tttctctgta
     5641 ttttttaatt ccaagaatgc catcttaacc agatggtttt cctgtccatt gttggtaatc
     5701 gccaatacct cacctgttgt gtcttcgcgc atactaaagc tatgaaaagc caggtcatct
     5761 gagaaataat tactatccac gatagcaatg gcgtaaacag gagcgatgtg tttgtagctc
     5821 tagtgagtat caccttctcg ctgacgaatt ttttcaagat tttgattaac ctgactgcac
     5881 aggtaagccc acaagcgatt gatgaaaaaa ttctgatgat ggacttgaat ctcaataatt
     5941 acttgagtac cgttatccaa ctccgccaag acgtctatac tggtataaaa atcctgcacc
     6001 gagtaaggca tggagagtaa tacgtgaata ttgctaccct ccaaaatggt cacatttttg
     6061 gctggcaaat ccagcatatc gcgaataaat tgacaagtga tttctggatt gctaaagatt
     6121 ttcttagcta ccaagtcatt ggttgggcta atgcccggat gacgtacagt catatttctt
     6181 ctctttttat tatatcacag ttttaaatct agctttacta gattcaccgc tactatctat
     6241 ttatttggaa aaaagacgaa aaaacctgag aatcatctca ggcttggtca ttaaattttt
     6301 ttctcaatat cgaaaagtgg agaaagtggt cgtttttcat gaatacgtac gatagcatcc
     6361 cctaggagat gagctattga aatctgctca atcttatcaa tcaaacgctc ttctggcaga
     6421 tagatggtat ccaaaacaac caatttctta atagctgatt tttggatatt gtccgtagca
     6481 ggaccagaaa gaactgggtg cgtacagctt gcatagactt caacagcacc agcttccgca
     6541 agagcatctg ccgcatgaca aatcgttcca gcggtatcaa tcatatcatc aatcaagata
     6601 caagtcttgc cttcaacctt accgatgatg ttcataactt cactagtatt catcttatca
     6661 acgctacgac gtttatcaat aatagcgata gatgttttca aaaattctgc caacttacga
     6721 gcacgagtca cccctccatg gtccgggctg acaaccacat agtcagaacc aaccatacca
     6781 cgacgctcaa aataatctgc aatcagagga gcacccatca aatgatccac aggaatatca
     6841 aagaatcctt gaatttgcgc agcatgcaag tcgatggtca ataaacgatc cactccagct
     6901 acttcaagca tatttgcgac aagttttgaa gtgattggct cacgcgctct cgcctttcta
     6961 tcctgacgtg catacccata gtaaggcatg acaacattga cagattctgc actcgcacgc
     7021 ttcaaagcat ctaccataat caaaatttca agcagattgt catttacagg cgaactagtt
     7081 gattgtaaga taaagacgtg tttcccacgg attgattctt caatgttgac ctgaatctct
     7141 ccatctgaaa attggcgaac acttgatttc cccaactcta tcccaatctc ctgcgccaca
     7201 cgttctgcca attctttatt agaagaaagg gcaaacagct ttaaatcaga aaaagacatg
     7261 atttcctccg gtatatatgt ataacttgtg cttttcacaa gattttccat ctaccattgt
     7321 agcgcttttt gcactatttt tcaatcaaaa ataaaagaag ggcaccatat ttgtaccctt
     7381 gcatcattct tttgaaaaat attctaggtc atcaactcat tatgtttctc aacaaagcaa
     7441 taagcatgat aaaaaccata gagagcaata gccgtaacca ctggaatcgc taaaggcaac
     7501 tctgtttcca actccacaaa aggagagtta aacaagaagt gagttcccaa ggctagacct
     7561 aggaaaataa gtccctgttt cttgccaatc ttctgtcctt tataggctct gtaaagcaag
     7621 taaaccccca ccacagccag acctgaaaaa gtccagtgag aggcaattcc tgagatgata
     7681 cgctctaaaa tcctcgaaat agtaaagtca aatccctccg gtaaatccgt acgaatatag
     7741 ccaatatcct caatcatttg gaatcccaaa ccagaagcag tccctagtaa aaacaaagat
     7801 tttaattttc gcacaggaat caaagctaaa acaaaaacaa gtggcaacaa tttcaagggc
     7861 tcttctacca aaggagccac aatcgcactt tcaaaggcat ttaaaaaagc actatctggg
     7921 aaaagaccac ccagtaaatc atggatatag gtattcgcaa agctagacaa ccagcctgaa
     7981 aggaacatcc cacccaataa agacaagatc aaggcgttct ttggcaattc ccattttttc
     8041 ccaatacgga aaaggaaata aagagccgga atcatgtaaa agagagctag aaagatagaa
     8101 actcccatta gtccatattc cgcgcctgat atcgaaccat ccgtatagta gatggtttca
     8161 tactgtaaac caatacatag caataaaata aaaataaata aaatactgtt tttcttcata
     8221 cactttcttt ctaaatgaat tttttacaat tctacaactg tcatacttcc tgtatccaca
     8281 tcgtaaatgg caccagagat aatgacatcg tctggtatta gggaagattc gataagcagt
     8341 ttcatatcct ctcgcacact ctcctctata tcttggaagg gcaagaagtc ctggtctgac
     8401 atatcgacac ctagttcctc tttcagatac tcctgaaaag gaccattttc aaaggtctga
     8461 gcaccacagt ctgtatggtg cagcaccaca atctctcttg tccccatttg ttgttgggaa
     8521 ataactagcg aacgaatcat gtcctcagtc actcgaccac ctgcattccg caagatatga
     8581 gcatccccaa gtgccaagcc tagagcttgt gcaacgtgca gacgtgagtc catacaggtc
     8641 acaatggcta ctcttgtttt gggtttaagt ggcagattta actgcccatg tagggcaaca
     8701 taagcctgat tggcttgcat aaactgttca aaatacgaca cgattccctc cttgaaaatt
     8761 tgatagtcaa atatttctcc tatcttatca tttttaagag gatttgtcac ggattatgca
     8821 aaaacctttt tcaaaacttc ctgaatggta gtcacaccaa tcacctgaat ttccttgggc
     8881 ggagtgatcc ctgtcaaaga atttttgggt acataaatct tagtaaagcc cagtttagca
     8941 gcttcgttga tgcgttgctc gatacgattc acgcgccgaa tctctcccgt caagcccagt
     9001 tcgcctacaa aacattcctg aggattggta ggcttgtctt tatagctcga agcaatagca
     9061 accgcaacgg ccaagtctat cgcaggttca tccaatttga caccgccagc agatttgaga
     9121 taggcatcct gattttgcaa gagaagacct gcccgctttt ccaaaacagc cataatcaga
     9181 ctagcacgat taaaatcaag tcctgtcgtc gtacgcttag catttccaaa catggtcggt
     9241 gtcaccaaag cctgaacttc cgccaaaatc gaacgcatcc cttccatggt cacaacgatt
     9301 gatgaaccag tcgctccatc caaacgctct tctaggaaaa cttgactcgg attgagtacc
     9361 tcaaccaaac cgcccgactg catctcaaaa atcccaattt cattggtaga accaaaacgg
     9421 tttttgaccg ctctcaagat acgaaaggta tggtggcgct ccccttcaaa gtaaagcacc
     9481 gtatccacca tatgctccaa catacgaggt ccagccaagg taccctcctt ggtcacatga
     9541 cctacgataa agatggcgat attatttgtc ttagccaact gcatgagctc agccgtcacc
     9601 tcacgcacct gagaaacaga cccctgcacc cctgaaatct caggagacat aatggtctga
     9661 atggagtcaa taataaggaa atctggttgg atgcgctcta cttctgcacg aacactctgc
     9721 atattggtct ctgcatagag gtaaaactcg ctatcaatat cacccaagcg ctctgcacgg
     9781 agtttaatct gctgggcaga ctcttcacca ctgacataaa gaaccgttcc aacttgagac
     9841 agctgggtag agacttgtag gagaagggtt gattttccaa tcccaggatc cccaccgatg
     9901 aggacgagac ttcctggtac cactccgcct ccaagtacac ggttgaattc ctccatctcc
     9961 gtcttggttc gattgacatt gattgaagtc acctcagcca gtttcatggg cttggttttc
    10021 tcacctgtca aggacacacg cgcattcttg acctcggcaa cctcaatctc ttctacaaaa
    10081 gaagaccaag acccacagtt ggggcatcgt cccagatatt taggggaatt atacccacaa
    10141 ttttgacata caaatgtcgc ttttttcttt gcgatgataa acctctttct atatctctaa
    10201 ctcacactca atcacttggc aaaaatcaat cttctcattt ggcacaaact ggcgcatgag
    10261 cattcgatga gcaacaacta ccacagtctg atgttctcga tacttagaca tacattctag
    10321 aaaccgagac ttcatttccg tagctgtctc atattgaata ggactattag gaagtaactc
    10381 ccccctgttt tctaaaaaca gtcttctagc tgtttcaaag ttttctattc ctgttttata
    10441 gacctgccat tcatgtaata aaggctctac tcttaaagga agacccgtag cacagaccac
    10501 atacgaagcc gtttctaaag ctcttgcgac tgcagaagat acgattattt cagctgacga
    10561 gagtaaagga tttttgctca atttctggac ttgctgccgt cccatatcag acaagggtgc
    10621 caaatctatc ccaaatccta tataagaacg ctcctctaac tcacggtaat ctggctcccc
    10681 atgacgtaca aagataatct tcattctagt gccctgtcga tccaaatcca ccagttcgaa
    10741 cgccatcagc cgcatctcca tctgcaatta agaaagtagc aaaaacagcc tggacaatac
    10801 gctccccaac ttcaagaaca acctcttggt ctgtgatatt cttcatctgc gcaaaaatat
    10861 gcccttcatt tccaggattt ccataataat ccccatcaat gaccccaact gagttaatta
    10921 aaaccaagcc cttcttacga ggatttgaag aacgatcata gaggtagaga acctcagtcg
    10981 gctgcatata agccttaacc cctgtcggaa ccaagacaat ctctcctggc gcaacaactg
    11041 tacgcacagc aacctttaag tcgtaaccag ccgcatgcgc tgtctcacgc ttgggcaata
    11101 aattttcatc tgtaaaactc gaaaccaatt caaaaccacg aattttcata attttctctt
    11161 ttctattatc atttattcta gattattcta tcttatttat tcggaaaaag cacgaaaaaa
    11221 agagcacaca attcaaatcg cttagggctg ctggattcct cccctgaccc gcttcacgca
    11281 gaactgttgc tccactattt attatatcac attcctattc attttaaaag caaaattatt
    11341 ttttccgtct atttctaaaa aagtcctgca taatagctgc gcattcatct tccaaaattc
    11401 ccgtttcaac ctctacacga tggttaagac gctcatctgt caagatatcg tacaaacttc
    11461 cagcagcgcc aaatttctgg tttttagccc catagaccac atttggaata cgggcaagcc
    11521 caatcgcccc actacacatg acacaaggtt caatggtcac aaaaagtatg caatccagca
    11581 agcgccagct ctcctcactc aagttcgcat cctctatagc cataatttcc gcatgcataa
    11641 ccgctcgctg taattcctca cgcgcattat gcccacgacc aatgatttcc ccatctttga
    11701 caatcacaca accaattgga atttcatcgt gttcaagagc aatctcagcc tctctcaaag
    11761 cctccctcat aaagacttct ttttcttcaa gcgtataata catctctttt ctcttttcct
    11821 acttatcgat tttattatta tatcatgaat cccaacacaa aaaaagccac cgaatgcggt
    11881 gactctatag ggagattatt atgaaaaaga aaagtttagg atatttgtta caacaagtta
    11941 ggaggtcttc ttgtaactgt ctatagtata cccgacctat cttaaacaaa tcttaaaaat
    12001 ctcttaggac caaacacttt ctaaaatatt tgtttgttca cgaccaggac ctactgagaa
    12061 agtagaaata cgaacgccaa ccaattcact cacacgacga acatagttac gcgcattctc
    12121 aggaagatct tccaaattgc gaactccggt aatatcttct gaccaacctg gcaactcttc
    12181 atagataggc ttgcaacgtt tcaattgctc aagactagct ggatagtagt caatacgttg
    12241 accgtcaaga tcataggcca cacagatttt cacagtatcc aaaccgctca aaacatcaat
    12301 agagttcaaa gaaaggttag taataccaga aacacgacgg ctatgacgca tcacaactga
    12361 gtcaaaccaa cctacacgac gtggacgacc agttgttgta ccatactcat gacccacttc
    12421 acggatacgt tctcccactt catcaaacaa ctcagttggg aaaggaccat ctcctacacg
    12481 actcgtataa gctttacata cacctacaac cttgtcaatc ttgcttggac cgacaccaga
    12541 accaattgtc acaccaccag ctacagggtt tgatgacgta acaaatggat aagtaccttg
    12601 gtcgatatct agcataacac cttgtgcacc ttcaaaaagc acacgtttgc cattatcaag
    12661 cgcatcattc aagataacag atgtatctat cacgtatttc ttgatttgtt gaccatattc
    12721 gtaatattct tcaaaaatat catcgaaaac aatctcttta ctgtcataca atttttcaaa
    12781 aagacgattc ttttcagcaa ggttacgttc taaacgctca cggaaaatat ctttatctaa
    12841 aagatctgca atacgaattc caacacgagc agccttgtcc atataagctg gaccaattcc
    12901 cttaattgtc gtaccaatct tattgtcgcc cttagcttct tcttgcaagc gatccaactc
    12961 gatatgataa ggcaaaataa catgcgcacg atcagaaata cgcaagttat cagttgttac
    13021 accttcctca tgaagatagc tcaactcttt tacaagagat ttaggattta caaccatacc
    13081 attcccaatg acagatattt tttcagggaa gaaaatccca gatggaatca agtgcaactt
    13141 aaatttctta ccgtcaatca caatcgtgtg accagcatta tcaccacctt ggtaacgtgc
    13201 aatcacttct gcattcgctg aaaggaagtc tgtaatcttc cctttacctt catcacccca
    13261 ttgggtacct acaacaacaa ctgaagtcat aatcttgtct gagccctcag gctcttcctt
    13321 tctcacatac atggcaggac tctcacctgc aattatatct tacaatttat tataataaaa
    13381 aatcgccttt ttatcaagaa gaaacaatag aaagatttgc tatttccaac tattaaaaaa
    13441 tgatttagaa aaattactag ctatttacta ttatctttcc ataaaagagt aaattagttc
    13501 ggaaatttag taaaattacc tcaacaagaa ataaaacccc gattcattac caatttttca
    13561 agatacaaac gataagcaac acgataatgg taaacgataa aatccctacg acaaccaatg
    13621 ccatatctca ctaaataata aattaaaaat ttaaaatgaa catgttccca gtcaaaatta
    13681 tcaccaaatg taggaccata ctcttcttca atactatcat agaaattagc catctgctca
    13741 taaatttttt gtaacataat caaatactcc ttttcttttt tataaactta ttctaacaaa
    13801 aaattttaca cattcactat caattcctga attgttaaaa taccagcctc aacaagataa
    13861 aaataggaaa agttgacaga atagaaacaa atttgctacc taaatttcaa acgattaaag
    13921 ttctaaaaag accgccttaa aacttttggg taaatcctat tagaactata atatttttat
    13981 ataggtatta tggttctgat tttctagtat aaaaaaattc aaactagaat ttttcttaga
    14041 aaaggccgtt ttaagtgcta tcattgctca aaaatggagg tcgctgagac ttctatcgtc
    14101 aagaagaatc accaaatccc tcgtatcatc aaccaaaaga ttgctcaaaa gttaattgaa
    14161 aagatttcta tgaccgatat tgctcatcag ctatcagctg gccattttaa cttcaactgt
    14221 cattcgaaag ctcaatgact tccactttga gcatgatttt tcgcgtcttc ctgagattat
    14281 gtcctaggac gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc
    14341 tttattgctc aggactttga taagctcaat atcataactg ttcttgagag cagaacacaa
    14401 gccatcatcc gaaatcccat ggatacaagg ctatcaagcg ctactggaag ctcattcaac
    14461 aagatagtca gaaactgagt gataaacgat tttatcgccc tacttttcgt atgcacttga
    14521 ctaataaaga aattctagat aaacttttga gctattccga aaacttgaaa caccactata
    14581 atctctatca gctcttgctt ttccacctct ttttcagact ctgtttaaaa ccttcctcaa
    14641 agataaagag aaaatcgtca acgcccttca attaccttat tccaaattcc aacgccaaac
    14701 tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt tttaggaact
    14761 ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tatatcttcg ctttcttcaa
    14821 cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc aattgaaaca
    14881 agaacaagac aaaagagcct cgtaaaaggt attgcaacgt ggtaatacct ttttgaggtt
    14941 ctttttgata tgagcccatg ttttctcaat aggattgtac tcaggtgagt agggaagaag
    15001 aggtaaaagt ttatgcccaa actcttcaca taaaagttct agcttaccca ttctatggaa
    15061 tcttgcattg tccataatat agtagattga aactagaata gtacacctct acttctaaaa
    15121 cattgttaga attcgatttt actgtcctga tcgatttgtc ctattcttat ttcattttac
    15181 tataacacga aatatattat tattacataa caaaaaagag gtctaaacct cttaactaaa
    15241 ttactccgcc agtaggactc gaacctacga catcatgatt aacagtcatg cgctactacc
    15301 aactgagcta tggcgga
//
LOCUS       DAVDHZ010000050        15117 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000050 DAVDHZ010000000
VERSION     DAVDHZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.051"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(126..416)
                     /locus_tag="VUR46_001881"
     CDS             complement(126..416)
                     /locus_tag="VUR46_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457243.1"
                     /translation="MLEQIIQSLFIIVAIGLILLVLYQIAKILGSLFVIGLLGLLAFM
                     EIYGIYLFFTERYLYVEDLAANGILSFTTFYIGFNVLLIFGLVAKVIRSRMA"
     gene            complement(431..730)
                     /locus_tag="VUR46_001882"
     CDS             complement(431..730)
                     /locus_tag="VUR46_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457244.1"
                     /translation="MTQTVEEQRYQLEEWLAKGFTSPEDRANYQALKEQYEDETLDYS
                     FSKREIIGQLDIIITTRENNFPDLDEVTKESYIDLIAQLDDLDKGQANYYRKQLV"
     gene            complement(800..7603)
                     /locus_tag="VUR46_001883"
     CDS             complement(800..7603)
                     /locus_tag="VUR46_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET5457245.1"
                     /translation="MIQEQLLEMLRARLPRDQILLESFLRYQAVHFDEDWESLIQDFT
                     THRGVVPSPDQVVRFETEVSAFVKASPFDEATDLSSYTRTFGQAGLKKLPQLNSDEKA
                     LVIEVALFNLATRFQLLDQEGAYQSISVASLLEKGKAANLVNVYRVANNLSDRISRDI
                     EQFLLTYEPELDTRPIETISESDEIEVEPSPEITFREESFVIMASLEEDLSQLNLRTG
                     KTEHLPAYEHLNLSQKFEILSHFDQVRNSRPKLPNLRRGEFDHEMEMMPIYEEEELLI
                     YLEADGTIYDLQRPLTPQEEVILTEIGQTILAENTEKLTSLGIDLANFDENKQGVLID
                     ATGRFRLKNADLALLGGYPNASVTQLALTTELLQMGLTHDRAEFFLTSQLKLEDLRPI
                     AYAFLHEYLDIEEARTFERDKQSQPDVSFRDWRERLTQTESEIIMPQETPQNPIVEEA
                     LKRYPIDSTVSYKGQDLKVIAIEESGVNDLIRIELQNDFTDVIEQNPVLFLRTLEEIT
                     QALHLPSAEEKEEVKQPSQELDLFSFMLDDENQEDVFQEPVMEKEVEKSETLEEEIDS
                     ELFEVIEMTPTTDFHFPEDLTNFYPKTTRDKVETNVAAMRLVKALEAEERQATPDEQE
                     LLAKYVGWGGLANEFFDEYNPKFSKEREALKTLVTDKEYSDMKQSSLTAYYTDPALIR
                     QMWEKLEQDGFTGGKILDPSMGTGNFFAAMPKHLRENSELYGVELDTITGAIAKHLHP
                     NSHIEVKGFETVAFNENSFDLVISNVPFANIRIADSRYDKPYMIHDYFVKKSLDLVHD
                     GGQVAIISSTGTMDKRTENILQDIRETTDFLGGVRLPDTAFKAVAGTNVTTDMLFFQK
                     HVDKDYQAYDIAFSGAIRYDKDDRIWLNPYFDGEYNPQVLGTYEVRNFNGGTLSVKGN
                     PDNLIADVQIALKQVKAPRVVEPSDIFINSDVLARQVIDTSIPADIRESLEQYSFGYK
                     DSTVYYRDNKGIRVGTKTEEISYYVSEEGHFKAWDTKHSQKQIDRFNALEVTDSTALD
                     VYVTEEPAKRGRFKGYFKKTVFYEAPLSEKEVARIKGMVDIRNSYQEVIAIQRYYDYD
                     KDEFNHLLGKLNRRYDNFVKRFGYLNSPVNRNLFDSDDKYSLLASLEDEGLDPSGKTI
                     IYTKSLAFEKALVRPEKEVTEVSSALDALNSSLADGRGVDLDYMMSIYQTDSKASLIE
                     ELGDAIIPDPEPYLNDREVVYVSRQDFLLGDVVTKLEIVDLLIKEDNSDFPWVYYQGL
                     LEDVKPPRVTLADIDYRIGSRWIPLAVYGKFAQETFMGQTFDLTAPEVSTVLEVSPID
                     GTMSYQSKFAFRYSTATDRSLGVPGSRYDSGRKIFENLLNSNQPTITKQVEDGDKKKH
                     VTDVEKTTVLRAKETQLQELFQDFVASYPEVQQMIEETYNSFYNRTVSKVYDGSHLTI
                     DGLAQNISLRPHQKNAIQRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLY
                     VVPSSLTAQFGQEIMKFFPTKNVYVTTKKDFARAKRKQFVSRIITGDYDAIVIGDSQF
                     EKIPMSQEKQVAYIQDKLDQLREIKQGSDSDYTVKEAERSIKGLEHQLEELQKLERDT
                     FIEFENLGIDFLFVDEAHHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQVQGEHD
                     YRNVVFATGTPVSNSISELYTMMSYIQPDVLERYQVSNFDSWVGAFGNIENSMELAPT
                     GDKYQPKKRFKKFVNLPELMRIYKETADIQTSDMLDLPVPEAKVIAVESELTEAQKYY
                     LEELVDRSDAIKSGSVDPSEDNMLKITGEARKLAIDMRLIDPAYTLSDNQKILQVVDN
                     VERIYREGELDKATQMIFSDIGTPKSKEEGFDVYNELKDLLVDRGIAKEAIAFVHDAN
                     TDEKKNSLSRKVNSGEVRILMASTEKGGTGLNVQSRMKAVHHLDVPWRPSDIVQRNGR
                     LIRQGNMHQEVDIYHYITKGSFDNYLWQTQENKLKYITQIMTSKDPVRSAEDIDEQTM
                     TASDFKALATGNPYLKLKMELENELTVLDNQKRAFHRSKDEYRHTISYCEQNLPALEK
                     RLSQYDLDIAQSLATKSQDFVMRFDNQMMDNRAEAGDYLRKLITYNRSETKEVRTLAN
                     FRGFELKMATRSPSEPLPDMVSLTISGSNQYSVSLDLKSDVGTIQRITNAIDHILEDQ
                     EKTEKMANNLKDKLAVARVEVEKVFPKEEDYQLVKAKYDILAPLVEQEAEVEEIDAAL
                     AKFNETTQPKKDLQLSLDI"
     gene            complement(7655..8206)
                     /locus_tag="VUR46_001884"
     CDS             complement(7655..8206)
                     /locus_tag="VUR46_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457246.1"
                     /translation="MAWNYDTISKTLSEMAQENYEDMVKALLTMELSIKSKSLLDRLY
                     QDFMGIDDLSLVSDDLRLRADGYQEQLQEELTDLLDKLYRTGEGASFIMEVIASNNIF
                     DTLVQYEVLDEDDYSSLTLETLQDIIQKDLPLTSQDYFGDVTYLALQKDLLDQKSHFL
                     QQYVTTLVDKLPQEKDQSTLVLD"
     gene            complement(8190..8381)
                     /locus_tag="VUR46_001885"
     CDS             complement(8190..8381)
                     /locus_tag="VUR46_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HET5457247.1"
                     /translation="MEPKSIYTMDSDQDGLTDAQELALGTNLFSSDTDSDGLTDLEEV
                     QQGLNPIQQGKESSYGLEL"
     gene            complement(8382..13286)
                     /locus_tag="VUR46_001886"
     CDS             complement(8382..13286)
                     /locus_tag="VUR46_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5457248.1"
                     /translation="MTKQCHHHFLVNQEQAEKHVFRKSKKYRTLCSVALGTMVTAVVA
                     WGGQVAQADEVTMPPLDKTVQLTENNATNLPEAQPAPVAEQTDSLASTGQSDGTITVT
                     VPHDTVTNAINQATAEGVTTVQDQPMDLGNTTSASDTSKQLDKAEADAAKQAEDITRV
                     TNTYKADKAAYEQDKTRVEKGNAALVASHKEATQAGKALNSSVDTTASEVQTQDKSAN
                     VTITTQTVPSGEGSTVSGYQDYTSAVAAIDKQNKASLADYITKKQAADAITAKNLAVQ
                     KENEAGLANAKAENEAITKRNQAEQKAIDDENKAGQAAVDTYNKNQQKLVTDREAEIA
                     AIIKRNKEKEEAAKKENEAIDAYNAKEMNRYKRDLADISKGEEGYISQALAQALNLNN
                     GEPQARHSADTRNPNRIIAKGDAMLGGYSKILDSTGFFVYDTFKTGETLSFTYQNLQN
                     VSFDGKKITKVAYDITNLVSPTETDSVQLVVPNDPTEGFIAYRNDGTGNWRTDKMEFR
                     VKAKYFLEDGSQVSFSKEKPGVFTHSSLNHNDIGLEYVKDTSGKFVPINGSTIQVTDE
                     GLARSLSSNRASDLNLPEEWDTSFSKYAYKGAIVSTVTSGNTYTVTFGQGDMPQNAGL
                     TYWFALNTLPVARTVKPYSPKPHVSPKLDPVPEPIKVVPKTFTPKTFTPEPPVIFKEK
                     PLEKVTQPRLTLTKVTFAKEPRSEPLPKAPQVPTVHYHDYRLTTTPEIMKKVVNTDQD
                     NLHDKTIAKDSTVIYPLTVDVFSSNRAKTTTLTFEDYLPAGYAFDKEKTQAENGNYTL
                     TFDEAKNFVTLTAKEALLQEVNQDLTKSYQLVAPKLYGSLQNDGATYSNSYKLLINKG
                     TSNAYTVTSNVVTVRTPGDGKITSRITPQKRNENEDGVVINDTVVALGTTNHYRLTWD
                     LDQYKGDTSSKETIARGFFFVDDYPEEVLDLVDKGTSITTLDGKAVSGITVKAYASLS
                     EAPKDLQDKLAHAKISPKGAFRIFQPNDNQAFYDQYVKTGTSLNLLTKMTVKDSLYGQ
                     TKTYRNKAYQVDFGNGYKTNEVTNTLVSPTPKKQNLNKDKVDINGKPMVVGSQNYYTL
                     SWDLDQYRGIKADKAQIAKGFYFVDDYPEEAVLPDDTAIQLTTSNGKAVIGVTVKNYT
                     SLSEAPKPLQASFEKRKIAPKGAFQVFMAEDPQAFYDSYVTKGQNITIVTPMTVREEM
                     LNSGKSYDNVAYQVDFGQAYETNTVTNHVPKVNPHKTNTNKEGVSIDGKTVLPNTVNY
                     YKIVLDYSQYKDLVVTEDTLAKGFYMVDDYPEEALTLNADGVQVMDKAGNLVKGISVK
                     AYASISEAPQVVQEAMAKRQLTPKGAIQVLSADDPKAFYETYVKTGQTLVVTLPMTIK
                     NELTKTGGKYENTAYQIDFSLAYVTETVVNNVPKLDPQKDVVIDLSQKENSLDGKEVA
                     LNQVFNYRLVGALIPGNRATPLIEYRFDDDYDESHDDYNGVYKAYTVVDVTLKDGTVL
                     LKGTEVTKYTLQHVDTSQGTVTISFDKEFLEKLAEESEFQADVYLQIKRIASGEVENT
                     VLHTVNGYTISSNTVKTTTPEPEPPTPNQPTPPQPLIPTQEPPVPASVLPNTGESQSL
                     LALVGGGLLLGLAYVLAKRKMEDN"
     gene            13480..14070
                     /locus_tag="VUR46_001887"
     CDS             13480..14070
                     /locus_tag="VUR46_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET5457249.1"
                     /translation="MSKKELLLEYINNHNGLITHRDCKKLGIPTIYLTRLEDEGVIFR
                     VEKGIYLSSSGDYDEYYFFQYRYPRTVFSYISSLYLQGLTDEIPQYFEVTVPKDYRFR
                     NRPLNLNSYTVSKDIINMGVTSVKTPMGNTVNVYNFERVLCDFILNRSNIDNELFVKT
                     VQTYSNFPEKNLAKLYDYAQKLNILDDVKRTLEVLL"
     gene            14067..14912
                     /locus_tag="VUR46_001888"
     CDS             14067..14912
                     /locus_tag="VUR46_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET5457250.1"
                     /translation="MNKAKLTALCHNISKQTGLTFNSVMTYYFLEVILKKLSRSSYAD
                     HYIFKGGFLLSNIIGVESRSTVDIDFLFHKQTLSEENVQQQLEEILSEVKNDIQFSIQ
                     SITTIKESDDYGGYRATILCQLENIKQIIHLDIATGDVVTPQPITYDYKAIFNDENFP
                     IIAYTIETVLAEKLQTIYSRSFLNSRSKDFYDIYILSKLKKDDIDLAQLKMACEKTFS
                     YRETELNFNNIIQLLETFKSDSTQQQQWQNYSKKYSYTKGISFSEILDEMIRLVSLLI
                     SLNNE"
BASE COUNT         4093 a         3209 c         2976 g         4839 t
ORIGIN      
        1 ataggaaatc gaacgacgga gcgactactc ctagggagat ttatcttttt ccacagagtt
       61 gtaggcaagt tcagttttca agatacaaat cattagaaga gtctgggaca atagtctcca
      121 ttattttatg ccatccgact tctaataacc tttgccacaa gtccgaatat aagtagcaca
      181 ttaaatccaa tatagaaagt ggtaaaactc aaaataccat tggccgctaa atcttcgaca
      241 taaaggtatc gctctgtgaa aaagagataa atgccataga tttccataaa ggctaggagg
      301 ccaagcagtc cgataacaaa cagacttcct aatattttcg caatctgata gaggacgagc
      361 aaaatcagcc ctattgctac gataatgaaa agactttgaa tgatttgttc taacatatct
      421 acgcctcttt ctacactaat tgcttacggt aatagttagc ctgcccctta tctaggtcat
      481 caagttgagc aattaagtca atatagcttt ctttggtcac ctcatctaag tctggaaaat
      541 tattttcacg agtggtaata atgatatcta attgaccaat gatttctcgc tttgaaaagc
      601 tgtaatcaag ggtttcatct tcatattgtt cctttaaggc ttggtagtta gctcggtctt
      661 cagggcttgt aaaacctttt gctagccatt cttctagttg gtatctttgt tcttctactg
      721 tttgggtcat gttctgttct cctttggtga tttcttaatg tcattttacc gcgttcaaaa
      781 ctatttgtca gcctttttat taaatatcaa gagaaagttg aaggtctttt ttcggttggg
      841 tcgtttcatt aaatttagct agtgctgcat caatttcctc aacctctgct tcttgttcta
      901 ccaagggagc taatatgtca tacttagctt taaccagctg ataatcctct tctttaggaa
      961 aaaccttctc tacttcaacc cttgcgactg ctagcttatc ttttagatta ttggccattt
     1021 tttctgtttt ttcttggtcc tctaggatat ggtcaatggc attagtaatg cgttggatgg
     1081 ttcccacatc tgatttcaag tctaaagaga cagaatactg gttgctacct gaaatggtta
     1141 aagacaccat atctggcaac ggctcactag gacttctggt tgccatttta agctcaaatc
     1201 ctctaaaatt agccagtgtt ctcacttctt tggtttcaga acggttatag gtaatgagtt
     1261 ttcgtagata gtctccagct tctgcacggt tatccatcat ttgattgtca aaccgcatga
     1321 caaaatcttg tgacttagtt gccaaagatt gagcaatatc aaggtcatat tgactgaggc
     1381 gtttctcaag ggcagggagg ttctgctcac agtaagaaat ggtatggcga tactcatctt
     1441 tggagcgatg aaaggcacgc ttttgattgt ccaataccgt caactcattc tctagttcca
     1501 tcttgagttt cagataagga ttacctgtcg ctaaagcctt aaagtctgaa gcggtcatgg
     1561 tttgttcatc aatgtcttct gccgaccgta ctgggtcttt agaggtcatg atttgcgtga
     1621 tgtatttgag tttattctcc tgagtttgcc agaggtagtt atcaaatgac cctttggtaa
     1681 tataatgata gatatctacc tcttggtgca tattgccttg acgaattaac ctaccattgc
     1741 gttggacaat atcagaggga cgccagggaa catctaaatg gtggactgct ttcatacgtg
     1801 actgtacatt taatcctgtt ccaccttttt ccgtagaagc catgagaatc ctgacttccc
     1861 cactattgac cttgcgtgag agagagtttt tcttctcatc cgtattagcg tcatgaacaa
     1921 aggcaattgc ttctttggca atccctctat ccactaagag gtctttcaat tcattgtaaa
     1981 catcaaaccc ttcttcttta cttttaggcg ttccaatatc agagaaaatc atctgggtag
     2041 ccttatcaag ctcaccctca cggtaaatgc gttccacatt gtccaccact tgaagaatct
     2101 tctgattgtc cgataaggta taggctgggt caatgagacg catgtcaata gctagttttc
     2161 tagcttcccc agttatcttt aacatattat cctcactagg gtcaacgcta cctgacttaa
     2221 tggcgtctga acggtcaacc aactcttcaa ggtagtattt ctgagcttct gtgagttcac
     2281 tctccaccgc aatgactttg gcttcaggta caggtaaatc aagcatatct gaggtctgaa
     2341 tatcagctgt ttccttataa atccgcatga gttcaggcag gttcacaaac ttcttaaagc
     2401 gtttcttagg ttggtactta tctcctgttg gggcaagttc catagaattc tcaatattcc
     2461 caaaagctcc cacccatgag tcaaagtttg agacttgata gcgttctaag acatctggtt
     2521 ggatataact catcatggta tagagttcac taatagagtt agagactggt gttcctgtcg
     2581 caaagaccac attacgatag tcgtgttctc cttgaacctg tctcactttc atttccatat
     2641 ccacattctt tttagaggtc gtgttggtaa ttcctgcgac attaccaagt ccagtaatgg
     2701 ggcgaatatt cttaaaatga tgagcttcgt ccacaaagag aaagtcaatc ccaaggtttt
     2761 caaactcaat aaaggtatct cgctccagtt tttggagttc ttccaattgg tgctccaacc
     2821 ccttgataga acgctctgct tctttaaccg tatagtcact atcactgcct tgtttaatct
     2881 ctcgtaattg gtccagctta tcttggatat aggcgacctg cttttcctga ctcatgggga
     2941 ttttctcaaa ctgggaatcc ccaatgacaa tggcatcgta gtcccctgtg atgatccgtg
     3001 agacaaactg cttacgtttg gctctcgcaa aatctttctt ggtcgtcacg taaacattct
     3061 tggttgggaa gaacttcatg atttcttggc caaactgagc ggtcagactt gatggcacca
     3121 cataaagagg cttatgcacc atacccaatt ctttcagttt gaatcctgcc ccaagcatgg
     3181 ttaaggtctt acctgaaccc acttcatgag ctagaagcgc tcgtttttct tccacaatgc
     3241 gttgaatagc attcttctgg tgagggcgaa gagaaatgtt ttgtgctagc ccatcaatgg
     3301 ttaaatggct gccatcataa acttttgaga ctgtacgatt ataaaagcta ttataggtct
     3361 cttcaatcat ctgttgcacc tctgggtaac tagccacaaa atcttggaag agttcttgaa
     3421 gttgtgtttc cttagcacga agaaccgttg tcttctccac gtccgtcaca tgctttttct
     3481 tatccccatc ttccacttgt ttggtaatgg ttggttgatt ggaattaagc aggttttcaa
     3541 agattttgcg accactatca tagcgtgacc caggaacacc taaacttcta tccgttgcgg
     3601 ttgaatatct aaaggcaaac ttagattggt aggacattgt gccatcaatc ggactaactt
     3661 caagaacagt tgatacctct ggggcggtca ggtcaaaagt ttgtcccata aaggtttctt
     3721 gggcaaattt cccataaacg gctagaggaa tccatcgtga gccaatccga taatcaatat
     3781 cagctaaagt cacacgtggt ggtttcacgt cttctaagag accttgataa tagacccaag
     3841 gaaaatcaga attgtcttct ttaatgagta agtccactat ctctagctta gtcactacat
     3901 ctcctaataa gaaatcctgc cgcgacacat ataccacttc cctatcgttt agatagggtt
     3961 ctgggtctgg aataatagcg tctcccaatt cctcaatcaa agacgctttg gaatccgtct
     4021 gataaataga catcatataa tccaaatcca ccccacgacc atctgcgagg ctggaattga
     4081 gagcatcaag ggcagaagac acctctgtta cttccttttc gggacgaacc aaggcttttt
     4141 caaaggcaag tgacttggtg taaatgatag tcttaccact tgggtcaagt ccttcatctt
     4201 ctagactagc aaggagcgaa tacttatcgt cactatcaaa tagattacgg ttcacaggac
     4261 tattcaaata tccaaatcgt ttaacaaagt tatcatatct gcgattgagt tttcctagca
     4321 agtgattaaa ctcgtctttg tcgtaatcat agtagcgttg aatggcaatc acctcttggt
     4381 agctatttcg aatatcgacc atccctttaa ttcgtgccac ttctttctca gacaaaggag
     4441 cctcataaaa gacggtcttt ttgaaatacc ccttaaatcg gccacgcttt gcaggttctt
     4501 ctgtcacata aacatcaaga gctgtgctat cagtcacctc taaggcatta aagcggtcaa
     4561 tctgcttttg agaatgcttg gtatcccatg ccttaaagtg accctcctcg ctcacatagt
     4621 agctgatttc ttcagtctta gtccctacac ggattccctt gttatctcga tagtaaactg
     4681 tggaatcctt ataaccaaaa ctatactgtt ctaaactctc tctgatatca gctggaatcg
     4741 aggtatcaat gacttgtctt gccagtacgt ctgaattgat gaaaatgtca gaaggttcaa
     4801 caactctagg cgctttaacc tgtttaagag caatctgaac atctgcaatc aagttatcag
     4861 gattgccttt aacagaaagg gtgcctccat taaagtttct cacctcataa gttccaagaa
     4921 cttgaggatt gtactccccg tcaaagtaag gattcagcca aatacggtca tccttgtcat
     4981 aacgaatagc acctgaaaag gcaatgtcat aagcttgata atccttgtcc acatgtttct
     5041 ggaagaacaa catatccgtt gtgacattgg tacctgcaac ggccttaaaa gccgtatctg
     5101 gcaaacgcac accaccaaga aaatcagttg tttcgcgaat gtcctggagg atattttctg
     5161 tccgtttgtc catggttcca gtggaggaaa tgatagccac ttgaccacca tcatgcacca
     5221 aatcaagcga ttttttaaca aaataatcat gaatcatata gggcttatca taacgactat
     5281 cggcaatcct gatattggca aacggcacat ttgagatgac caaatcaaag ctattctcat
     5341 taaaggcaac ggtctcaaag cccttcactt caatgtgact atttggatgg aggtgcttgg
     5401 caatagctcc tgtaatcgtg tctaattcca caccatacaa ctcactattt tctctcaggt
     5461 gtttaggcat agccgcaaag aagtttcctg tgcccatcga agggtctagg attttacctc
     5521 ctgtaaagcc atcctgctcc aacttctccc acatctgacg gataagagca gggtctgtgt
     5581 aataggcagt caaagaggat tgtttcatgt ccgaatactc tttatctgtg actagcgttt
     5641 ttaatgcctc acgttcctta gaaaatttag gattatactc gtcaaagaac tcattagcaa
     5701 gccctcccca gcccacatat ttagcaagga gttcttgttc atcaggcgtg gcttgtcgtt
     5761 cttcagcttc aagagctttt acaagacgca tggcagccac gttcgtttca accttatctc
     5821 ttgttgtctt agggtaaaag tttgtcagat cttctgggaa gtgaaaatca gtggttggtg
     5881 tcatctcaat gacttcaaaa agctctgaat caatctcttc ttcaagagtt tcagattttt
     5941 ccacttcttt ttccatgact ggttcttgaa aaacgtcttc ttggttctca tcgtctagca
     6001 taaaggaaaa gaggtctaat tcttggctag gttgtttcac ttcttctttt tcctcggcag
     6061 aaggaagatg gagagcctga gtgatctcct ctaatgtccg taagaaaaga actggatttt
     6121 gttcaatcac atctgtaaaa tcattttgta gttcaatccg aatcaggtca ttgacacctg
     6181 actcttctat ggcaatcacc tttaagtcct gccccttata ggacaccgtg gaatcaatcg
     6241 gataacgttt aagggcttcc tctacaatag gattttgagg tgtttcttga ggcatgataa
     6301 tttcagattc tgtttgtgtt aggcgctctc gccagtctct aaaggatacg tctggctggg
     6361 actgtttgtc cctttcaaag gttctagctt cttcaatatc gaggtattca tgtaagaaag
     6421 cataggcaat cggtcttaag tcttctaact ttaactgact ggtcaagaag aactctgccc
     6481 tgtcatgcgt tagtcccatc tgaagcaatt ctgttgtaag agctaattga gtgacggatg
     6541 cgttaggata gccccctaat aaggctaagt ctgcattctt caaacggaaa cgccctgtgg
     6601 catctatcag taccccttgt ttattctcat caaagttagc taagtctatc cctaaactgg
     6661 tcagtttctc agtattctct gctaaaatcg tttgaccaat ttcagttaag atcacttctt
     6721 cttgcggtgt taggggacgt tgtaagtcgt aaatcgtccc atctgcttct aaatagatta
     6781 atagctcttc ttcctcatag ataggcatca tttccatctc atgatcaaac tctccacgtc
     6841 ttagatttgg cagttttgga cgactatttc tcacttggtc aaaatgactc aatatctcaa
     6901 acttctgaga caagtttaga tgttcatagg ctggtaaatg ttctgttttc cctgttcgca
     6961 aattgagttg cgagaggtct tcttcaagac tcgccatgat gacaaaactc tcttcacgaa
     7021 aggtaatttc tggactgggt tctacttcta tttcgtcact ctcggagata gtctcaatag
     7081 gtctggtatc cagctccggt tcataagtta agagaaattg ttcaatgtca cggctaatac
     7141 gatcagataa gttgttagcg actcggtaga cgttgaccaa gttagcagct ttgccttttt
     7201 ccaaaagaga agctaccgaa atagactgat aagctccctc ttggtctaat agctgaaagc
     7261 gagtagctag gttaaagagg gctacctcaa tcaccaaggc tttctcatcg ctgtttaact
     7321 gaggtaactt ctttaggcct gcttggccaa aggtccgcgt atagctactg aggtctgtcg
     7381 cttcgtcaaa agggctcgcc ttcacaaaag cagaaacttc tgtttcaaag cgaaccactt
     7441 gatcaggtga ggggactact cctctatggg ttgtaaaatc ttggataagg ctctcccaat
     7501 cttcatcaaa atgaactgct tgatagcgta aaaaggattc taaaagaatc tggtcacgtg
     7561 gcaatcttgc ccgcaacatc tcgagtaact gctcttgaat catacgttcc tccaaatcaa
     7621 aaaaggagct gagaggtagt ctcagcccac tgctttagtc taggactaag gtgctttggt
     7681 ctttttcttg tggcaactta tccactaaag tcgtcacata ctgttgtaag aaatggcttt
     7741 tctggtctaa caaatctttc tgcaaggcaa gataggtcac atctccaaaa taatcttgac
     7801 tagtgagagg caagtccttt tggataatat cttgcaaggt ttctaaggtg agcgatgaat
     7861 aatcgtcctc atccaaaacc tcatattgaa caagggtatc aaaaatatta ttagacgcta
     7921 tcacttccat aatgaaacta gctccctctc ctgttcgata gagtttatct aacaaatccg
     7981 tgagttcttc ttgaagctgt tcctgataac cgtctgctct taggcgcagg tcatcactga
     8041 ctaaagacaa gtcatcaatg cccataaagt cttgatagag cctgtcaaga agtgacttgc
     8101 ttttgatact caattccatg gttaataagg ctttgaccat atcttcatag ttttcttgtg
     8161 ccatctcaga gagagttttt gaaatcgtgt cataattcca agccataact gctctcctta
     8221 ccttgttgaa ttggattcaa gccttgttgg acttcttcaa ggtctgtcag tccatcacta
     8281 tccgtatcac tgctaaaaag attggtccct agagctaact cctgagcatc cgttaagcca
     8341 tcttggtctg aatccattgt gtaaatgctt ttaggttcca tttaattgtc ctccattttg
     8401 cgtttagcaa ggacgtaggc taagcctaaa agaagtcctc caccgacaag cgccaaaaga
     8461 gattgactct ctcctgtatt tggtaagaca cttgctggaa ctggtggttc ttgtgttgga
     8521 ataagtggtt ggggtggtgt tggttgattc ggagttggtg gctctggttc aggagtagtt
     8581 gttttaaccg tgtttgaact gatggtgtag ccattgacgg tatgtagtac cgtattttct
     8641 acttcacctg aagcgattcg ttttatctgc aagtaaacat ctgcctgaaa ctcggattct
     8701 tctgctagtt tttctaggaa ttccttgtca aaactgatgg taaccgttcc ttgtgacgtg
     8761 tcgacatgtt gtagcgtgta cttagtcact tctgtccctt ttagtaaaac cgtcccatct
     8821 tttagagtga catctaccac agtataagcc ttgtaaacac cattatagtc gtcatggctt
     8881 tcatcgtaat catcgtcaaa gcggtattcg atgagtggtg tcgcacgatt accaggaata
     8941 agtgctccca ccaagcggta gttaaagacc tgattcaagg caacttcttt tccatcaaga
     9001 ctgttctcct tttgtgacaa atcaatcacc acatcttttt gtgggtctag ttttggaaca
     9061 ttattgacca ctgtttctgt cacataagcc aaactaaagt caatctgata agccgtgttt
     9121 tcatacttgc caccagtctt tgtcaactca ttcttaatgg tcatcggaag cgtcaccacc
     9181 aaggtttgac ctgtcttaac ataggtctcg taaaaagctt ttggatcatc agcacttaaa
     9241 acttgaatgg ctccttttgg tgtaagttgg cgtttggcca tagcttcttg caccacttga
     9301 ggcgcttctg atatcgaagc ataggctttg acagaaatcc ctttgacaag atttcccgcc
     9361 ttatccatca cttgaacacc gtctgcattt agtgttagag cttcttctgg atagtcatct
     9421 accatgtaaa aacctttggc aagggtatcc tccgtcacta ccaagtcctt gtactgacta
     9481 taatccagaa caatcttata gtaatttacg gtattaggaa gaacggtttt gccatcaata
     9541 gacactccct ctttattggt attggtctta tgaggattta cctttggcac gtgattggtc
     9601 accgtattgg tttcataggc ttgcccaaag tctacttggt aagccacgtt atcataagac
     9661 ttccctgaat taagcatctc ctcacgaact gtcatcggtg taacgatggt aatgttttgg
     9721 cctttggtca cataagaatc ataaaaggct tgtggatctt ctgccataaa gacttggaaa
     9781 gctcctttag gcgcaatctt gcgtttctca aaggatgctt gtaggggttt aggggcttct
     9841 gataaactcg tgtagttttt taccgtaaca cctatgacag ccttgccgtt agatgtcgtt
     9901 agttgaatag ctgtgtcatc tggtagcaca gcttcttcag gatagtcatc cacaaagtag
     9961 aagccttttg cgatttgagc tttatcagct ttaatgccac ggtattggtc taaatcccat
    10021 gacaaggtat agtagttttg tgaacccact accatcggtt ttccattgat gtccacttta
    10081 tccttattaa ggttttgttt cttaggtgtg gggctgacaa gggtattggt cacctcattt
    10141 gttttatagc cattcccaaa atcaacttgg taggctttgt ttcgataagt cttagtttga
    10201 ccataaaggc tgtctttgac ggtcattttg gtgagaaggt tcaaagaggt tcctgtttta
    10261 acgtactggt catagaaagc ctgattgtcg ttaggctgga agattcggaa agctccttta
    10321 ggagaaatct tggcatgagc gagtttatct tgaaggtctt taggagcttc tgacagcgac
    10381 gcataggcct taacagtaat ccctgatacg gctttaccat caagagtggt gatacttgtt
    10441 cctttatcca ccaaatccaa gacttcttct gggtaatcat ccacaaagaa gaaaccacga
    10501 gcaatcgttt ctttagaaga ggtatcacct ttatattgat ctaaatccca cgtcaaacgg
    10561 taatggttag tcgttcctaa agccaccacc gtatcgttaa tgaccacacc gtcttcattc
    10621 tcattgcgtt tttgaggagt aatacggcta gtgattttcc catcaccagg tgtacgaacg
    10681 gtcaccacgt tagaggtcac tgtataggca tttgacgttc ccttattgat gaggagctta
    10741 taactattgg aataggtagc cccatcattt tgaaggctac cataaagttt aggagccacc
    10801 agttgataag acttagtgag gtcttgattg acctcttgaa gcaaggcttc tttggcagtc
    10861 agggtcacaa agttcttagc ttcatcaaag gtaagcgtat aattcccatt ttctgcttgt
    10921 gttttttctt tatcaaaggc atagcctgct ggaaggtaat cttcaaacgt aagggtagtt
    10981 gttttggcac gatttgaaga aaaaacgtca actgttaaag gataaataac tgtcgaatcc
    11041 ttggcgatag ttttgtcatg aagattgtct tggtcggtat tgaccacttt tttcatgatt
    11101 tcaggggtcg ttgtcagacg atagtcgtga taatgaaccg ttggtacttg tggtgcttta
    11161 ggcaaaggtt cagacctagg ttctttagca aaggtcacct ttgtcaaagt caagcgaggt
    11221 tgagtcactt tctccagtgg tttttcctta aagatcacag gtggctctgg ggtaaaggtc
    11281 tttggggtaa aagtttttgg cacgacttta atcggctctg ggactgggtc tagttttggg
    11341 ctcacatgtg gtttcggact ataaggtttg acggttcgtg caacaggtaa ggtgtttaag
    11401 gcaaaccaat aggtcagtcc tgcattctgg ggcatatcgc cttgtccaaa agtcacggtg
    11461 taggtattgc ctgatgtgac ggttgagaca atcgctccct tgtaagcata cttgctaaaa
    11521 gaggtatccc attcttctgg gaggttcaaa tcactagcac ggtttgaaga aagtgaacgt
    11581 gctaggcctt catctgtcac ttgaatggtt gagccattga tagggacaaa cttgcctgat
    11641 gtgtctttga catactctaa gccaatgtca ttatgattaa gtgaggaatg ggtaaagaca
    11701 cctggttttt ccttgctaaa gctgacttgc gagccatcct ctaagaaata cttggctttg
    11761 acacgaaact ccattttatc ggttcgccaa ttccctgtcc catcattacg ataggcaata
    11821 aagccttctg ttgggtcatt aggcacaact aattgtacag aatccgtctc agttggagac
    11881 actaggtttg tgatgtcata agcgactttg gtaatctttt taccatcaaa actcacattt
    11941 tgaaggtttt gataagtgaa tgaaagggtt tctccagttt taaaggtatc atagacgaag
    12001 aaaccagtag aatctaggat tttagaatac ccaccaagca tggcgtcacc cttagcaatg
    12061 atgcgattag gatttctcgt gtcagctgaa tgtcgggctt gcggttcccc attgttcaag
    12121 ttgagagcct gagcaagagc ttgtgagatg taaccttcct ctccttttga gatgtcagct
    12181 aagtcacgtt tgtatcggtt catttctttg gcattgtagg catcaatggc ttcattttct
    12241 ttcttagcag cttcttcttt ctccttattg cgttttataa tagcagcaat ctcagcttca
    12301 cggtctgtca ccaatttttg ttggttctta ttgtaggtat ccacagcagc ttgacctgct
    12361 ttattttcat catcaatcgc tttttgttct gcttgattgc gtttagtaat cgcttcattc
    12421 tctgcctttg cattcgcaag acctgcttca ttttcctttt gaacagctag gttctttgcg
    12481 gtaatggcat ctgcggcttg ttttttcgtg atatagtccg caagactagc cttgttttgt
    12541 ttatcaatag cagctaccgc agatgtgtag tcctgataac ctgaaacagt tgatccctct
    12601 cctgacggaa cggtttgagt tgtaatagtc acgttcgcag acttgtcctg agtctgcact
    12661 tctgaagccg tggtatctac tgaactattc aaggcctttc ctgcttgagt agcttcttta
    12721 tgactagcaa ccaacgcagc attccctttt tcgacacgag ttttatcttg ttcataagcg
    12781 gctttgtcag ctttataggt atttgtcacc cgagtgatgt cctcagcttg tttggcagca
    12841 tccgcttccg ctttatctaa ttgcttactg gtatcactcg cagaggttgt gtttcctaaa
    12901 tccatcggct ggtcttgaac agtagttacc ccttcagcag ttgcttgatt gatggcattg
    12961 gttaccgtat catgaggaac cgttactgtg atagtcccat ctgattgacc ggttgacgca
    13021 aggctatcag tctgttcagc aactggtgct ggctgagctt ctggtaaatt ggtcgcatta
    13081 ttttccgtta actgaacagt cttatctagt ggtggcattg tcacttcgtc agcctgggct
    13141 acttgcccac cccaagcgac aacagctgtc accatagttc caagtgctac cgaacacagc
    13201 gtacggtact tcttactttt acggaagaca tgcttttctg cttgttcctg attgactaaa
    13261 aagtgatgat gacattgttt ggtcataaaa agtccttctt ttcttttgat aagtagcaac
    13321 aatctgtcac tctctcctca tcataaaaaa gacgacttga ttttggtatc acatcacata
    13381 agagactagt aaatgctaat taataacacc caaaatgttg cttctgcacc gttaaaatgc
    13441 taaaattaaa gtacaaaagc aacaaagaaa ggagagatta tgtctaaaaa agaattgtta
    13501 cttgagtaca taaacaatca caatggtctg attacccata gagattgtaa aaaattaggt
    13561 attccaacca tctatctaac gagactagaa gacgaaggag ttatctttag ggtcgaaaaa
    13621 ggtatctatc tatcttctag tggagattat gatgaatact atttcttcca atatcgttat
    13681 cctagaactg tcttttctta tatctcttct ctttatctac agggacttac tgatgaaatt
    13741 cctcaatatt ttgaagtaac agttcccaag gactatcgtt ttagaaacag accattgaat
    13801 ctaaatagct acactgtttc taaagatatt attaacatgg gggttaccag tgtcaaaaca
    13861 cctatgggaa atacggttaa cgtttataat tttgaacgtg tactatgcga ttttatcctt
    13921 aatcgaagta acattgataa tgagctcttt gttaaaacag ttcaaactta tagtaacttc
    13981 cctgaaaaaa atcttgcaaa actttatgac tatgctcaaa aattaaatat cttagatgat
    14041 gttaaacgaa ccttggaggt actcttatga ataaagcaaa attaacagca ctctgccata
    14101 acatttctaa acagaccggc ctaactttta actcagtaat gacctactac tttcttgaag
    14161 tcattttgaa aaagctaagt cgaagttctt atgcagacca ttatattttt aagggaggat
    14221 ttttgctttc aaatatcata ggagttgaat ctcgtagcac ggtggatatt gattttctct
    14281 ttcataaaca aacactatca gaagaaaatg ttcaacaaca actggaagaa attttaagtg
    14341 aagtaaaaaa cgatattcaa ttttcaattc aatccattac aacgattaaa gaaagcgatg
    14401 attacggtgg ttaccgagca accattttgt gtcaactgga aaacattaaa caaattatcc
    14461 atttagatat tgcgactgga gatgttgtta cacctcagcc cattacctac gattacaaag
    14521 ctatttttaa tgatgagaat ttccccatca ttgcttatac aattgaaacg gtgctagctg
    14581 aaaaattaca aaccatttac tcaaggagct tcttaaacag tcgtagcaaa gatttttacg
    14641 atatctatat cctttcaaag ttaaagaaag acgacattga tttggcacaa ttaaagatgg
    14701 cttgtgaaaa aaccttctct tatcgtgaaa ctgaactcaa ttttaataac atcattcaac
    14761 tgcttgaaac cttcaaatct gactctactc agcagcaaca atggcaaaat tattcaaaaa
    14821 aatatagtta tacaaaaggg atttcctttt cagaaatcct tgatgagatg attcgtttag
    14881 tcagtctttt aatctcttta aacaatgaat aaaacaactt ttcggttatc ttttaaccga
    14941 tacagacaac attaaaagga tatgcgagca actccttacc ttgttcgcat atcctttttc
    15001 ttatttcatc gtatacgcaa aactaatcgt accatctact cctgataact tacggaaggt
    15061 gtaattggga ttaccattgt agttggtctc tgagatgagg aacgatccat ctgggta
//
LOCUS       DAVDHZ010000051        14626 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000051 DAVDHZ010000000
VERSION     DAVDHZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14626
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.052"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            90..452
                     /locus_tag="VUR46_001889"
     CDS             90..452
                     /locus_tag="VUR46_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457251.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKIFVTVIGYFEINIDENITDILYVNGTAILYLYLRSIVSIVSAIDSSEAMLL
                     PIINVLELLDKSQPFEEE"
     gene            1497..2489
                     /locus_tag="VUR46_001890"
     CDS             1497..2489
                     /locus_tag="VUR46_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5457252.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2491..3309
                     /locus_tag="VUR46_001891"
     CDS             2491..3309
                     /locus_tag="VUR46_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET5457253.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3311..4096
                     /locus_tag="VUR46_001892"
     CDS             3311..4096
                     /locus_tag="VUR46_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5457254.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4135..4413
                     /locus_tag="VUR46_001893"
     CDS             4135..4413
                     /locus_tag="VUR46_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET5457255.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4398..4595
                     /locus_tag="VUR46_001894"
     CDS             4398..4595
                     /locus_tag="VUR46_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457256.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(5021..5113)
                     /locus_tag="VUR46_001895"
                     /pseudo
     CDS             complement(5021..5113)
                     /locus_tag="VUR46_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            5327..11746
                     /locus_tag="VUR46_001896"
     CDS             5327..11746
                     /locus_tag="VUR46_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET5457257.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            12373..12849
                     /locus_tag="VUR46_001897"
     CDS             12373..12849
                     /locus_tag="VUR46_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5457258.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            12887..13192
                     /locus_tag="VUR46_001898"
     CDS             12887..13192
                     /locus_tag="VUR46_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5457259.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFDPGIPVIEAGLILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            13240..>14626
                     /locus_tag="VUR46_001899"
     CDS             13240..>14626
                     /locus_tag="VUR46_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET5457260.1"
                     /translation="MYAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAV"
BASE COUNT         4972 a         2273 c         2896 g         4485 t
ORIGIN      
        1 cagttccatc tacaacctca aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt
       61 gctctttggt tttcattgag tataacacat tgttagaagt tggtttaaat ttcctaatca
      121 gtttgttcac atttaccttc gatatattat atcccatagt taaggttggt catacagatg
      181 attatagtca tggagccgta aaacttagtg tttctttagt tgacaaagat gccatgaaaa
      241 aaatatttgt aactgtaata ggatattttg aaataaatat agatgaaaat atcaccgata
      301 ttctatacgt aaatggtact gctattcttt atctttattt acgttctatt gtttcaatag
      361 tttcggcaat tgatagcagt gaagcaatgt tgctacctat cattaatgtt ttagagttac
      421 tagataaatc tcaacctttt gaagaagaat aatttattag ctcactaaat tgagggtaag
      481 gaaaagtaaa agcagtaaga aaaatgtctt gcattataca gcaacctttt gggaatgagt
      541 ggatggattg aataaaattt gattaagagt ggatgattta tctgtagatt attattggac
      601 agttagtctt gaagtagtct aagaattagg ttataatcag tagaagcctt gctaataatg
      661 aggaggttag tttatgtata gtagactgaa tctaaaatag tacgaaacaa ttgctaaaac
      721 atttatagaa attaatttta ctttcccaat cgatttgttc tcatcttatt tcaatccgct
      781 atatattatg gtatcgaatc ttcatcagaa tgataaaatt aatcaattga tatctgatta
      841 caaacagaat atgaaagctt tttatatcac tattgaaaaa tttatacgag atgatgaaag
      901 ccttaagtgt tattttataa aggttatttc aagtcgttcc aaggtaacaa gtctagatca
      961 gattgaagct gataaaacga tacaaagaaa atattcaagt gagctaaaaa aatttattgg
     1021 attttataat gagattattt gtgaggaaaa tagtttccta catgtacgaa agaggtggtc
     1081 gagttggttt aggtagtcga tgcgtgagtt gataattctc agggtatgga cttctttttc
     1141 atgaatgagg taaaagagca ggtattgttt agagacaatc attctgagca tattttctgg
     1201 atagagggag tatccgattt tatgatcaaa gttaataccg ccctctggtg agaagatgag
     1261 taggttggta atttaaacta ttaaacagaa tttttgatta aaagtattat ttcatgagag
     1321 aaatcctaat ttcacaatcc ataggcaaac gcttgcattt cgttttttat tggactataa
     1381 taggttggta taaagccttc tgtagtaata aaatgtagaa ggtgtagaaa gtaaggattt
     1441 agaatatttg tagttaaaaa cacaatgttg ctattcctta cgatagggag atagatatgg
     1501 caatgataga agtggaacat cttcagaaaa attttgtgaa gactgttaag gaaccgggct
     1561 tgaagggggc tttgcgctcc tttattcatc ctgaaaagca gacctttgaa gcggtcaagg
     1621 atttgacctt tgaggttcca aaagggcaga ttttaggatt tatcggggca aatggtgctg
     1681 ggaagtcgac aaccattaaa atgctgacag gaattttgaa accaacatct ggtttttgtc
     1741 ggattaacgg caagattccc caggacaatc ggcaagatta tgtcaaagat attggcgtag
     1801 tctttggaca acgcacccag ctatggtggg atttggctct gcaagagacc tacactgtct
     1861 taaaagagat ttatgatgtg ccagactcgc tctttcataa gcgtatggac tttttgaatg
     1921 aagtcttgga tttgaaggac tttatcaagg atcccgtgcg gactctttca ctgggacaac
     1981 ggatgcgggc ggatattgcg gcctccttgc tccacaatcc caaggttctt tttttagatg
     2041 agccgaccat tggtttggac gtttcggtta aggataatat tcgtcgggca attactcaga
     2101 tcaatcaaga ggaagaaact accattcttt tgaccactca cgatttgagt gatattgagc
     2161 aactttgtga tcggattttc atgattgaca aggggcaaga gatttttgat ggaacggtga
     2221 gccaactcaa ggagaccttt ggtaagatga agactctctc ttttgaactg ctaccaggtc
     2281 aaagtcatct cgtctctcac tatgacggtc tgtctgatat gaccattgat agacaaggaa
     2341 acagcctcaa cattgaattt gatagttctc gctaccagtc agctgacatt atcaagcaaa
     2401 ccctgtctga ttttgaaatc cgcgatttga agatggtgga tacggatatt gaggatatta
     2461 tccgtcgctt ctaccgaaag gagctctagg atgatcaaat tgtggagacg ttataaaccc
     2521 tttatcaatg caggggttca ggagttgatt acttaccgag tcaactttat tctctatcgg
     2581 attggcgatg tcatgggggc ttttgtggcc ttttatctct ggaaggctgt ctttgattct
     2641 tcgcaagagt ctttgattca gggcttcagt atggcggata tcaccctcta catcatcatg
     2701 agttttgtga ccaatcttct gactagatcc gattcgtcct ttatgattgg ggaggaggtc
     2761 aaggatggct ccattatcat gcgtttgttg cgaccagtgc attttgcggc ctcctatctt
     2821 ttcaccgagc ttggttccaa gtggttgatt tttatcagcg ttggccttcc atttttaagt
     2881 gtcattgtct tgatgaaaat catatcgggt caaggtattg tagaggtgct aggattaact
     2941 gtcatttatc tttttagctt aacgctcgcc tatctgatta actttttctt taatatttgc
     3001 tttggatttt cagcctttgt gtttaaaaat ctttggggtt ccaacctact taagacttcc
     3061 atagtggctt ttatgtcggg gagtttgatt cccttggcat tttttccaaa ggttgtttca
     3121 gatattctct cctttttgcc tttttcatcc ttgatttata ctccagttat gatcattgtt
     3181 ggaaaatacg atgccagtca gattcttcag gcactccttt tgcagttctt ctggctctta
     3241 gtgatggtgg gattgtctca gttaatttgg aaacgggtcc agtcctttat caccattcaa
     3301 ggaggttagt atgaaaaaat atcaacgaat gcatctgatt tttatcagac aatacatcaa
     3361 acaaatcatg gaatataagg tagattttgt ggttggtgtc ttgggagtct ttctgactca
     3421 aggcttgaat ctcttgtttc tcaatgtcat ctttcaacat attccattcc tagaaggctg
     3481 gacctttcaa gagatagctt tcatttatgg attttccttg attcccaagg gaatggacca
     3541 tctctttttt gacaatctct gggcactagg gcaacgccta gtccgaaaag gggagtttga
     3601 caagtatctg actcgtccca tcaatcctct ctttcacatc ctagttgaaa cctttcagat
     3661 tgatgccttg ggtgaactct tagtcggtgg tattttattg ggaacaacag tgaccagcat
     3721 tgtttggact cttccaaaat tcctgctttt cctagtttgt attccttttg cgaccttgat
     3781 ttatacttct cttaaaatcg caacagccag tatcgccttt tggactaagc agtcaggcgc
     3841 catgatttac atcttctata tgttcaatga ctttgctaag tatccgattt ctatttacaa
     3901 ttctcttctt cgttggttga ttagctttat cgtgcctttc gcctttacag cctactatcc
     3961 agctagctat ttcttacagg aaaaggatgt gttctttaac gtaggaggtt tgatgttgat
     4021 ttctctggtt ttctttgtta tttcccttaa actttgggat aagggcttag attcctacga
     4081 aagtgcgggt tcgtaaaagc taaagtaaga ctaaaatcaa gaaagaaact tatgatgttt
     4141 gtaattgaag aagtcaagga tgaaaatcaa aaaaaggcag ttgtcgctga ggttttgaag
     4201 gatttgccag aatggtttgg aatcccagaa agcacacaag cctatataga aggaaccacg
     4261 acactgcaag tttggaccgc ctatcaggag agtgatttga ctagatttgt aagcttatcc
     4321 tattcgagtg aagattgtgc agagattgat tgtctcggcg taaaaaagct tatcaaggta
     4381 gaaaaattgg gagccaattg cttgctactt tagagagtga agctcgtaaa aaagttggtt
     4441 atctgcaggt caaaacagtg gcagaaggtt ctaataaaga ttatgatcga acaaatgact
     4501 tttatcgagg tcttggcttt aaaaagttag agatttttcc tcaactatgg aatccgcaaa
     4561 atccttgtca gattttgatt aaaaagcttg aataatatta cttgacatct attctcagag
     4621 tgctatactg taagtgtaat cgccgattta gcttagttgg tagagcaagg cactcgtaaa
     4681 gcctaggtta taggtagata aacgactgag gatttgaaaa aatagatagg tagaagataa
     4741 ccgttaagcc ttactcttag cggttattta tattgtttaa tagcgctaat attttatcaa
     4801 ttatgcctgt tttcgtgttt ctggtagttg ttcaagttta ttgctactat ttttgatggt
     4861 atgaatgtgc ttataatgta tcccggttaa cgaaagtttt ggacttatac tcttcgaaaa
     4921 tctcttcaaa ccacgtcaac gtcgccttgc cgtgcgtatg gttactgact tcgtcagttc
     4981 tatccacaac ctcaaaacag tgttttgagc tgactacgtc agttccatct acaacctcaa
     5041 aacactgttt tgagcaatct gcggctagtt tcctagtttg ctctttgatt ttcattgagt
     5101 actaatctta ttttttaatg tgtgctaaaa aataaattaa ctaatgttaa tttttttgac
     5161 ttaaattttt ttaaatgata tactgttttt atagagagat aacaattata tataaatgta
     5221 ctactctatt tcctagataa tacttagtaa aactttttat aacaaaggct agcaaagtta
     5281 aagtttatta tctattggaa gttatataaa tatgtaagga attaaaatga aaaaaagtac
     5341 agtattgtca ttaaccacag ctgcagttat tttagcagcc tatgccccta atgaggtagt
     5401 cttagcagac acatctagct ctgaagatgc tttaagcatc tctgataaag aaaaagtagc
     5461 agaaaataaa gagaaacata aagatattca taatgctata gaaacttcaa aggatactga
     5521 agaaaagaaa acaacaatta ttgaggaaaa agaagttgtt agtaaaaatc ctgtgataga
     5581 cactaaaact agcaatgaag aagcaaaaat caaagaagaa aattccaata aatcccaagg
     5641 agatcatacg gactcatttg tgaataaaaa cacagaaaat cccaaaaaag aagataaagt
     5701 tgtctatatt gctgaattta aagataagga atctggatca aaagcaatca aggaactatc
     5761 cagtcttaag aatacaaaag ttttatatac ttatgataga atttttaacg gtggtgctat
     5821 tgaaacaact caagataatc tgaataaaat taaacaaata gaaggtatta catcggttga
     5881 aagggcacaa aaagtccaac ccatgatgaa tcatgccaga aaggaaattg gagttgagga
     5941 agctattgat tacctaaagt ctatcaatgc tccgtttggg aaaaattttg atggtagagg
     6001 tatggtcatt tcaaatatcg atactggaac agattatagg cataaggcta tgagaatcga
     6061 tgatgatgcc aaagcctcaa tgagatttaa aaaagaagac ttaaaaggaa ctgataaaaa
     6121 ttattggttg agtgataaaa tccctcatgc gttcaattat tataatggtg gcaaaatcac
     6181 tgtagaaaaa tatgatgatg gaagggatta ttttgaccca catgggatgc atattgcagg
     6241 gattcttgct ggaaatgata ctgaacaaga tatcaaaaac tttaacggca tagatggaat
     6301 tgcacctaat gcacaaattt tctcttacaa aatgtattct gacgcaggat ctgggtttgc
     6361 gggtgatgaa acaatgtttc atgctattga agattctatc aaacacaacg ttgatgttgt
     6421 ttcggtatca tctggtttta caggaacagg tcttgtaggt gagaaatatt ggcaagctat
     6481 tagggcatta agaaaagcag gcattccaat ggttgtcgct acgggtaact atgcgacttc
     6541 tgcttcaagt tcttcatggg atttagtagc aaataatcat ctgaaaatga ccgacactgg
     6601 aaatgtaaca cgaactgcag cacatgaaga tgcgatagcg gtcgcttctg ctaaaaatca
     6661 aacagttgag tttgataaag ttaacatagg tggagaaagt tttaaataca gaaatatagg
     6721 ggcctttttc gataagaata aaatcacaac aaatgaagat ggaacaaaag ctcctagtaa
     6781 attaaaattt gtatatatag gcaaggggca agaccaagat ttgataggtt tggatcttag
     6841 gggcaaaatt gcagtaatgg atagaattta tacaaaggat ttaaaaaatg cttttaaaaa
     6901 agctatggat aagggtgcac gcgccattat ggttgtaaat actgtaaatt actacaatag
     6961 agataattgg acagagcttc cagctatggg atatgaagcg gatgaaggta ctaaaagtca
     7021 agtgttttca atttcaggag atgatggtgt aaagctatgg aacatgatta atcctaataa
     7081 aaaaactgaa gtcaaaagaa ataataaaga agattttaaa gataaattgg agcaatacta
     7141 tccaattgat atggaaagtt ttaattccaa caaaccgaat gtaggtgacg aaaaagagat
     7201 tgactttaag tttgcacctg acacagacaa agaactttat aaagaagata tcatcgttcc
     7261 agcaggatct acatcttggg ggccaagaat agatttactt ttaaaacccg atgtttcagc
     7321 acctggtaaa aatattaaat ccacgcttaa tgttattaat ggcaaatcaa cttatggcta
     7381 tatgtcagga actagtatgg cgactccaat cgtggcagct tctactgttt tgattagacc
     7441 taaattaaag gaaatgcttg aaagacctgt attgaaaaat cttaagggag atgacaaaat
     7501 agatcttaca agtcttacaa aaattgccct acaaaatact gcgcgaccta tgatggatgc
     7561 aacttcttgg aaagaaaaaa gtcaatactt tgcatcacct agacaacagg gagcaggcct
     7621 aattaatgtg gccaatgctt tgagaaatga agttgtagca actttcaaaa acactgattc
     7681 taaaggtttg gtaaactcat atggttccat ttctcttaaa gaaataaaag gtgataaaaa
     7741 atactttaca atcaagcttc acaatacatc aaacagacct ttgactttta aagtttcagc
     7801 atcagcgata actacagatt ctctaactga cagattaaaa ctggatgaaa catataaaga
     7861 tgaaaaatct ccagatggta agcaaattgt tccagaaatt cacccagaaa aagtcaaagg
     7921 agcaaatatc acatttgagc atgatacttt cactataggc gcaaattcta gctttgattt
     7981 gaatgcggtt ataaatgttg gagaggccaa aaacaaaaat aaatttgtag aatcatttat
     8041 tcattttgag tcagtggaag aaatggaagc tctaaactcc aacgggaaga aaataaactt
     8101 ccaaccttct ttgtcgatgc ctctaatggg atttgctggg aattggaacc acgaaccaat
     8161 ccttgataaa tgggcttggg aagaagggtc aagatcaaaa acactgggag gttatgatga
     8221 tgatggtaaa ccgaaaattc caggaacctt aaataaggga attggtggag aacatggtat
     8281 agataaattt aatccagcag gagttataca aaatagaaaa gataaaaata caacatccct
     8341 ggatcaaaat ccagaattat ttgctttcaa taaccaaggg atcaacgctc catcatcaag
     8401 tggttctaag attgctaaca tttatccttt agattcaaat ggaaatcctc aagatgctca
     8461 acttgaaaga ggattaacac cttctccact tgtattaaga agtgcagaag aaggattgat
     8521 ttcaatagta aatacaaata aagagggaga aaatcaaaga gacttaaaag tcatttcgag
     8581 agaacacttt attagaggaa ttttaaattc taaaagcaat gatgcaaagg gaatcaaatc
     8641 atctaaacta aaagtttggg gtgacttgaa gtgggatgga ctcatctata atcctagagg
     8701 tagagaagaa aatgcaccag aaagtaagga taatcaagat cctgctacta agataagagg
     8761 tcaatttgaa ccgattgcag aaggtcaata tttctataaa tttaaatata gattaactaa
     8821 agattaccca tggcaggttt cctatattcc tgtaaaaatt gataacaccg cccctaagat
     8881 tgtttcggtt gatttttcaa atcctgaaaa aattaagttg attacaaagg atacttatca
     8941 taaggtaaaa gatcagtata agaatgaaac gctatttgcg agagatcaaa aagaacatcc
     9001 tgaaaaattt gacgagattg cgaacgaagt ttggtatgct ggcgccgctc ttgttaatga
     9061 agatggagag gttgaaaaaa atcttgaagt aacttacgca ggtgagggtc aaggaagaaa
     9121 tagaaaactt gacaaagacg gaaataccat ttatgaaatt aaaggtgcgg gagatttaag
     9181 gggaaaaatc attgaagtca ttgcattaga tggttctagc aatttcacaa agattcatag
     9241 aattaaattt gctaatcagg ctgatgaaaa ggggatgatt tcctattatc tagtagatcc
     9301 tgatcaagat tcatctaaat atcaaaagct tggcgagatt gcagaatcta aatttaaaaa
     9361 tttaggaaat ggaaaagagg gtagtctaaa aaaagataca actggggtag aacatcatca
     9421 tcaagaaaat gaagagtcta ttaaagaaaa atctagtttt actattgata gaaatatttc
     9481 aacaattaga gactttgaaa ataaagacct aaagaaactc attaaaaaga aatataagga
     9541 agaagacgac tttgtaactg gtggaaaaag aacagtagaa cttgattata aatatgacga
     9601 taaaggaaat ataactgcct atgaagatga aagtgctcta gaatatgaaa ctgaaaaatt
     9661 tgacgaaata aaatcaaaaa tttatggtgt tctaagccca tctaaagatg gacactttga
     9721 aattcttgga aagataagca atgtttctaa aaatgccaag gtatattatg gaaataacta
     9781 taaatttata gaaatcaaag cgactaagta tgactcacat tcaaaaacga tgacatttga
     9841 tttatacgct aatattaatg atattgtgga tggattagct tttgctggag atatgcggtt
     9901 ttttgttaaa gatgatgatc gaataaaagc tgaaactaaa attagaatgc ctgaaaaaaa
     9961 taaggaaact aaagcagaat atccctatgt atcaagttat gggaatgtaa tcgaattagg
    10021 agaaggagat ctttcaaaga acaaaccaga caatttaact aaaatggaat ctggtaaaat
    10081 ctattctgat tcagaaaaac aacaatatct gttaaaggat aacatcattc taagaaaagg
    10141 ctatgcacta aaagtgacta cctataatcc tggaaaaacg gatatgttag aagggaatgg
    10201 agtctatagc aaggaagata tagcaaaaat acaaaaggcc aatcctaatc taagagtcct
    10261 ttcagaaaca acaatttatg ctgatagtag aaatgttgaa gatggaagaa gtacccaagc
    10321 tgtattaatg tcggctttgg acggctttaa cattataagg tatcaagtgt ttacatttaa
    10381 aatgaacgat aaaggggaag ctatcgataa agacggaaat cttgtgacag attcttctaa
    10441 acttgtatta tttggtaagg atgataaaga atacactgga gaggataagt ccaatgtaga
    10501 agctataaaa gaagatggct ccatgttatt tattgatacc aaaccagtaa acctttcaat
    10561 ggataagaac tactttaatc catctaaatc taataaaatt tatgtacgaa atccagaatt
    10621 ttatttaaga ggtaagattt ctgataaggg tggttttaac tgggaattga gagttaatga
    10681 atcggttgta gataattatt taatctacgg agatttacac attgataaca ctagagattt
    10741 taatattaag ttgaatgtta aagacggtga catcatggac tggggaatga aagactataa
    10801 agcaaacgga tttccagata aggtaacaga tatggatgga aatgtttatc ttcaaactgg
    10861 ctatagcgat ttgaatgcta aagcagttgg agtccactat cagtttttat atgataatgt
    10921 taaacccgaa gtaaacattg atcctaaggg aaatactagt atcgaatatg ctgatggaaa
    10981 atctgtagtc tttaacatca atgataaaag aaataatgga ttcgatggtg agattcaaga
    11041 acaacatatt tatgtaaatg gaaaagaata tacatcattt gatgatatta aacaaataac
    11101 agacaagaca ctaaacatta agattgttgt aaaagatttt gcaagaaata caaccgtaaa
    11161 agaattcatt ttaaataaag atacgggaga ggtaagtgaa ttaaaacctc atagggtaac
    11221 tgtgaccatt caaaatggaa aagaaatgag ttcaacgata gtgtcggaag aagattttat
    11281 tttacctgtt tataagggtg aattagaaaa aggataccaa tttgatggtt gggaaatttc
    11341 tggtttcgaa ggtaaaaaag acgctggcta tgttattaat ctatcaaaag atacctttat
    11401 aaaacctgta ttcaagaaaa tagaggagaa aaaggaggaa gaaaataaac ctacttttga
    11461 tgtatcgaaa aagaaagata acccacaagt aaaccatagt caattaaatg aaagtcacag
    11521 aaaagaggat ttacaaagag aagatcattc acaaaaatct gattcaacta aggatgttac
    11581 agctacagtt cttgataaaa acaatatcag tagtaaatca actactaaca atcctaataa
    11641 gttgccaaaa actggaacag caagcggagc ccagacacta ttagctgccg gaataatgtt
    11701 tatagtagga atttttcttg gattgaagaa aaaaaatcaa gattaagata aaagctatag
    11761 aaaaaaatgg tttatgtact gagattagat agtgaggtga tgacatagtt ttgtgaaaac
    11821 agccatttat aactcaatta tttagtttac ttcactattg atactatttg gagttattaa
    11881 tggacttagt ttagataact aatgaattga ttgaaagggt tagtattgac aatattggtc
    11941 atattgatta gaaaatagag tctatcaaaa tttaaaggct aatagaggtg atgagacaat
    12001 ttcaaggaat taagtagcgt ttggttgctt aattcctttt tatttggaag gaagtttttc
    12061 gtaaccgccc aataacgaag tctattggac ggttacgata tgatcactga cttcgtcagt
    12121 cttatctaca acctcaaaac tgtgttttga gcaacctgcg gctagcttcc tagtttactc
    12181 tttgattttc attgagtatt agaacagaaa aaatgcttgg agtatttgtt tgtgtgttta
    12241 tttttatata acaaactata aacaaaacaa aaatataaaa aaagagacaa aaaagaacag
    12301 aaagtaattg acaacggttt catatagtgt tatacttatg gcataaagtt aatggaaaga
    12361 agggaaaaac ttatggtatt agattatttc tttgacaaaa accttgtgtt ttgcttagaa
    12421 gcggataatc aagaacaact ctttgatcag gttgcaactt tattggaaga acgagaaatt
    12481 gtcactccaa cttatcgtga agctttgatc acgcgtgaaa agtcatttcc aactggctta
    12541 gatatggaat ttctaggaaa ggacttgcca aatgtagcga ttcctcatac agatattgtt
    12601 cataatctag ctgagaaagt ggtggttgtt cgattagaga aaccagtaac ttttcacaat
    12661 atgatagctc ctgataagga agtagaagta tccttgctct tctttatcat caataactca
    12721 agttcaagtc aaaccaacat tcttgctcag ttgatggact tctttactgg aaatggtcat
    12781 cttgaagacc tatcaaaaat ttccgaacca gaaaaacttt atgcttacat tgctgaagca
    12841 accgcttaat cttgtttatt aaaaaataaa atcggaggaa atccatatga ttaaaattct
    12901 tgctgcctgc ggtgcaggtg ttaactcaag tcaccaaatt aaaagtgctc ttgaagaaga
    12961 actttcaaac cgtggttatg atgttcactg tgatgcagtc atggtgaaag atgtaaacga
    13021 agaccttatg aaaggttacg atatctttac accaatcgct gcaacagacc ttggttttga
    13081 cccaggtatt ccagttatcg aagctggact aatcttattc cgtatcccag caatgagtgc
    13141 tccagtattt gacaatattg aagcagctat caaagaacac gggttaagct aattttaatt
    13201 tgttaacatt catataacat aaaaaaggga ggaactgtta tgtatgcaat ctttgaccta
    13261 atcggaaagg ttttcaatcc cattttagaa atgggtggac ctgtcatcat gttaatcatt
    13321 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
    13381 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
    13441 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat taccgacgtt
    13501 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
    13561 atcatgttga ttgtcaacat agtgatgcta gctatgaaga aaaccgatac acttgatgtc
    13621 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
    13681 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
    13741 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
    13801 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
    13861 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
    13921 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
    13981 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
    14041 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
    14101 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
    14161 ggtattacaa acgttgctac taaacgtctt caaggacgta aattcaatat cggtcttgac
    14221 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
    14281 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
    14341 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
    14401 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac ccttattgca
    14461 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
    14521 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
    14581 ggtaacacta caactggtga tatcaaagca atccttggtg cagtag
//
LOCUS       DAVDHZ010000052        14449 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000052 DAVDHZ010000000
VERSION     DAVDHZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.053"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(184..756)
                     /locus_tag="VUR46_001900"
     CDS             complement(184..756)
                     /locus_tag="VUR46_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET5457261.1"
                     /translation="MSTMKNKQEILESFRKNPDMMAILTIIQNLELTDSWLAAGSVRN
                     FIWNLLSDKSPFDFETDVDVIFFDPDISYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTAPYTSSRDAMSKYPERCTAVGLRLNEEPALELFTPYGLEDILNFQVRPTPHFL
                     ENQERMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(737..1708)
                     /gene="ruvB"
                     /locus_tag="VUR46_001901"
     CDS             complement(737..1708)
                     /gene="ruvB"
                     /locus_tag="VUR46_001901"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET5457262.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNDLEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYGGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRMATAKAYEHLGYEYNEK"
     gene            1868..1960
                     /locus_tag="VUR46_001902"
     CDS             1868..1960
                     /locus_tag="VUR46_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET5457263.1"
                     /translation="MMELVLKTIIGPFVVGVVLRLVDKWLNKDK"
     gene            2275..2367
                     /locus_tag="VUR46_001903"
     CDS             2275..2367
                     /locus_tag="VUR46_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET5457264.1"
                     /translation="MMDTILKTIIGPIVVGVVLRLVDKWLNKDK"
     gene            2708..2800
                     /locus_tag="VUR46_001904"
     CDS             2708..2800
                     /locus_tag="VUR46_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET5457265.1"
                     /translation="MMELILKTIIGPIVVGVVLRLVDKWLNKDR"
     gene            complement(3628..4044)
                     /locus_tag="VUR46_001905"
     CDS             complement(3628..4044)
                     /locus_tag="VUR46_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457266.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4056..4751)
                     /locus_tag="VUR46_001906"
     CDS             complement(4056..4751)
                     /locus_tag="VUR46_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457267.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            complement(4945..7446)
                     /locus_tag="VUR46_001907"
     CDS             complement(4945..7446)
                     /locus_tag="VUR46_001907"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET5457268.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLTAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLIEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            complement(7901..8989)
                     /locus_tag="VUR46_001908"
     CDS             complement(7901..8989)
                     /locus_tag="VUR46_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET5457269.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(9007..9675)
                     /locus_tag="VUR46_001909"
     CDS             complement(9007..9675)
                     /locus_tag="VUR46_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET5457270.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(9694..12132)
                     /locus_tag="VUR46_001910"
     CDS             complement(9694..12132)
                     /locus_tag="VUR46_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET5457271.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELELFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDSASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(12289..13581)
                     /locus_tag="VUR46_001911"
     CDS             complement(12289..13581)
                     /locus_tag="VUR46_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5457272.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFETMIPAFVIFLSSMIVYILASSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAAIVYGSIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKIQDRLAYQNEIK"
     gene            complement(13598..13906)
                     /locus_tag="VUR46_001912"
     CDS             complement(13598..13906)
                     /locus_tag="VUR46_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5457273.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(13952..14272)
                     /locus_tag="VUR46_001913"
     CDS             complement(13952..14272)
                     /locus_tag="VUR46_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5457274.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
BASE COUNT         4463 a         3141 c         2408 g         4437 t
ORIGIN      
        1 cccattttct tctatcacta agctatttat tctcaggcac caagcccatt tttcaaaaaa
       61 ataagccgcc tgattgggcg actttatttt tatagggaga ttattatgaa aaagttttag
      121 gagtttaagt taaggtcttc ttaacttatg aacttagtgt acactcccta gcttaaagtt
      181 tccttaagta tttttaaaaa tcaaattttt ccatttctcc tgccaatttt tcttggataa
      241 acgtgtttga tagagttcca ttcgttcttg attctctaaa aaatgaggag ttggacgaac
      301 ttgaaaattc aaaatatcct ccagaccgta tggagtaaag agttccaaag caggttcttc
      361 attcaagcgc agtccaacag ccgtacatcg ttctggatac ttactcatag catcacggga
      421 actggtatag ggagcagtat gagggctgtg ctggtgcata tagacttgat ttttcaattc
      481 ccactggtac tgaggaaagt cctctcgcag ttttttctcc agtaataagg tttcctcata
      541 agaaatatcc ggatcaaaga aaatcacatc tacatctgtt tcaaagtcaa aaggtgattt
      601 gtctgacaag agattccaga tgaaatttct gacagaacct gctgccaacc aggaatctgt
      661 caactccagg ttttggatga tagtcagaat agccatcata tctggatttt ttctaaaaga
      721 ctctagaatt tcttgcttat ttttcattgt actcataccc caaatgctca tatgccttag
      781 cagtcgccat ccgtccagac cgtgtccgca tgataaaacc tttttgaatc aagtaaggct
      841 catacatgtc ttctacagtc tcacgctcct cggcaatatt gacagaaaga gttcctaatc
      901 cgacagggcc accaccgtac atctcaatca tggtgcgaag gattttttga tccacatagt
      961 ccaaaccttc gtggtcaaca tccagcatag tcaaagcctt atcggtaata acatcatcga
     1021 taaccccatt ccccattatc tgggcaaaat cgcgcacgcg cttgaggaga cgattggcaa
     1081 tacgaggggt cccacgacta cgtagggcca actcagatgc tgcctcatga gtgatttcca
     1141 tctcaaaaat atctgccgtc cgctcgacaa tttctgtcaa gtcagcatgg gcataatact
     1201 ccatatggcc tgtaatccca aaacgtgccc gtagtggatt tgagagcata ccagcccgag
     1261 tcgtcgcacc aatcaaggta aaaggtggta actccaaatg aacactacga ctaccctcac
     1321 cagccccaat cataatatct atgtagaagt cctccatagc actataaagc acctcttcca
     1381 ctgacattgg caagcgatga atctcatcaa taaaaaggac atccccaggc tctaaatcat
     1441 tcaaaattgc taccagatca ccggcttttt caatgacagg cccagaggtc tgctttagat
     1501 ttacacctag ttcgttggca ataacaaagg ccatggtcgt ttttcccaag cctggaggcc
     1561 caaataagag cacatgatcc agcgcttcat cccgcatttt ggcagcctca ataaagattt
     1621 gtagctggtc cttgaccttg tcctgcccaa tatattcacg taagtactga ggacggagcg
     1681 tgcgttctac taactcctcg tcccctatta tctcattgtc taaaattcta ctcatggctc
     1741 tattatatca aaaatccaag ccacaaacaa aaagccaccc gattgggtaa ctcctgagtt
     1801 tagcacttat gtggtataat atcatacggc actgctacac cgcctacgaa aggaggtgag
     1861 atagcccatg atggaattag tactcaaaac tatcatcgga ccatttgtgg tcggtgtcgt
     1921 tcttcgatta gtcgataaat ggctaaacaa ggacaaatag tgtcaaaaaa agaccccaag
     1981 cttatttggt cgtgagcttg gggtcttttc tagtccatga tatagaacta gtactcaatt
     2041 cctttttatt atcccatagt tcacaaattt tgtcaaagtt ttacattttc atccccgcca
     2101 attccccgac caaaatccga aaaatatcga aaaatgattt ttagaatagt ccccaaaagc
     2161 ctaaaataga gccaaaaaac tccacctgat tgggtgaatt ccgactttaa cacttatgtg
     2221 gtataatatt gttcggcact tctacaccgc ctacgaaagg aggtgaatta gcccatgatg
     2281 gatacaatac ttaaaactat catcggacca attgtggtcg gtgtcgttct tcgattagtc
     2341 gataaatggc taaacaagga caaatagtgt caaaaagacc ccaagcttat ttggtcgtga
     2401 gcttggggtc ttttctagcc tatgatatag acacaatact taattccctt ttattatccc
     2461 atagttcaca aaatttgtca aaggtttata tcttcatcaa ttcagcttct ccaactttag
     2521 aatctgtcca ataaaattta taagattaag caaaagttat cggaaaatga tgtttaaaat
     2581 agtccccaaa agcctgaaat agagcaaaaa aactccacct gattgggtgc ctcccgagtt
     2641 taatacttat gtggtataat attctacggc actgctacac cgcctacgaa aggaggtgag
     2701 atagcccatg atggaactaa tccttaaaac tatcatcgga ccaattgtgg tcggtgttgt
     2761 tcttcgctta gtcgataaat ggctaaacaa agatagatag tgtcaaaaaa gaccccgagc
     2821 ttaatgtgga agttagcttg gggtcttttc tagtccatga tatagaacta atccttaatt
     2881 cctctccatt atcccacagt tcacaaaatt tgtcaaaact ttacatcctc agcttctcaa
     2941 gctttaaccg ctttacaaca agactttcaa gtttaagaga aaattaggga ttctatcaat
     3001 ttcatagaaa ttttgattta gtaaacgaag agacaatctt atatgtcact cctcatttaa
     3061 tacgccacta ctggacaagc aaaatcatta ttacagcagt ttcagtcctt caattaacag
     3121 tcacttacaa tcaaattgag tttgaagtag ctgaagtaac aacaaaccta tttcttagtc
     3181 atattttcta aaaaagttcc cgccaattcc ccgaccaaaa tccgaaaaat accaaaaaat
     3241 atcgaaaaat gatttttaga atagtcccca aaagcctgaa ataaagccaa aaaactccac
     3301 ctgattgggt ggagttaagg gagattatta tgaaaaagaa aagtttagga ttttattaaa
     3361 taaagttagg aggtctttat ttaataacta tatgatacaa gacaaagctt aaaactagct
     3421 taacttttct caaattctac catttttcaa aaaatttcta ttaccatcac ctcaccccac
     3481 aaaaagtcac ctgattgggt gacttcatta ggagattatg atgaaaaaaa cttttggatt
     3541 ttattaaata aagttaggag gtctttattt aatgactata taatactaga ccatccttaa
     3601 attttgctta agaaaaaaca agttttgtta ttttttacga ttcatccaag tcatccctat
     3661 acaattatag gtggataaga tttcaaagcc catagaacga tagaagccca aggttctttc
     3721 tgtctcttct gtcaccagct ggacttgata ggcatctttg taatcctcta aagcctcttt
     3781 catcaaggca ctaccaattc cttgacgctg atagattggt aaaacgatta aatcctgaac
     3841 caatactgat gagaatccat ctccaaccaa acgaatcaag cccaccacag catcaccatc
     3901 aagtgccaga taaattacta atgaatgaga taaggcctgc tccagcatct ctggttgatg
     3961 ggtataattt gtccaaccga cagcctgata gagatgtaaa acatcctcta gcttgacaat
     4021 ttcttgcttt ttaatagtaa tcatctcaac acctcttaaa gttctctcaa gctcttgtac
     4081 tgctgtccat ttttatcaaa attttcagga cgcaaccatg tttccaaacg atctttgact
     4141 tgaggccagt ccttatcaat catagacaac caatccgtat ctctcgtacg tcccttataa
     4201 accactgcct gacggaaggt tccttcataa ataaagctca aacgctccgc agctcgtctg
     4261 gatggcagat ttaaggcatc gcatttccac tcgtagcgac gatagtttag ctcctcaaaa
     4321 acatagcgag ctaggagata ctgagcttca gttcctatcc gtgtacccct tagctctgga
     4381 gaaaaagtga ctgctccgac ttctattact cggttattct ggtcaatgcg catgagagaa
     4441 aaagatccca aagccttacc agtcgccttg tctatgattg catagtaaaa acggtcctta
     4501 cgagccaaca tctgatgtaa aaggctaacc agctccccca tatctgctac tggctcctga
     4561 aaaaggtagg tccacatctc ctgaggcgta tcaggcccat aaacagctag caaatcctcc
     4621 gcatgctttt ccactgaaag agcctctatc ctagcataac gcccttctaa gaaatcaata
     4681 gaaggcagtt cacctggtgt ataaccttcc attgactccc caatcatttg accatattca
     4741 tttactggca tagctttctc cttttttcac ttttcaaact ttatagttgc ccatagtata
     4801 ccatactttc ataagaagat tcaaaaaatc ctccagattc tactctgaag gattcctacc
     4861 ttatttcaca acgatattaa cgagtttagt tggctcaaac agtttaggaa actgtttgag
     4921 gttggaaatc agcaaataaa ttggttattt tacaacaata ttaaccaatt tatttggtac
     4981 actaatcact ttcacgattt ccttaccgtc aatttctgct ttgacttttt catccgctag
     5041 agcaatttct tgcaattctt cacgtgatag gtctttagcg accatgagtt tggcacggac
     5101 tttacctttg atttggacaa cgatttcgat ttcgtcttca atcagtttac tttcgtccca
     5161 tgttggccaa gtcacgtaag agattgactc acctgttgca gcaacagttt gccagagttc
     5221 ttctgccaag tgaggtgcaa atggggcagt caattggata aatcctttgg catagtcaac
     5281 atagagcttg tcttccttgt tagccgcatt gacaaagacc ataagttggg caatggctgt
     5341 gttgaatttg agggaatcaa tttgctctgt gacagcttta acagtttcgt tgtaaacctt
     5401 gtcaagagcg ccattgtttt ccgcaacaat ttccttactt ctaatcaaac ggtaaacacg
     5461 gtcaaggaac ttacgacttc cttccagacc ttcttctgac caagcaatcg aagcatcgag
     5521 tggtcccatg aacatttcat agacacgaag ggtatcagca ccgtattgtt ccaccacatc
     5581 gtctgggttg acaacgttct tgagcgattt agacatcttg gctggcgctt gctccaactc
     5641 ttcccctgtt tccacatgga agaaagaacc atcacgtttt tcaaccttgt cagtcgccac
     5701 aagagcccca cggtggtcac gatagcttgt tcccaaaatc attccttggt taaagagttt
     5761 ttggaatggt tccttagttg gaacaacacc gaggtcatag aggaatttat gccagaaacg
     5821 agcgtaaagc aagtgaagta cagcatgttc cgcaccaccc acgtagatat ctactggcaa
     5881 ccattgtttg agcagatcct cgtcagccaa tttctcagta ttgtgtgggt caatatagcg
     5941 gaggtagtac cagcttgaac ctgcccattg tggcatagta tttgtttcac gacgaccttt
     6001 gacaccatct tcacgagtca cttcaagcca gtctgtcaag ttagctagtg gactttcacc
     6061 agtacctgag ggacggatat ccttggttac aggcaagaca agtggcaatt cactttcagg
     6121 gacagctgtt gaagttccat cttcccaatg aatgattggg attggctcac cccagtaacg
     6181 ttgacggcta aagagccagt cgcggagacg gtaggttacc ttctcttgtc cacagccttt
     6241 ttcttccaac caagccacaa tcttggcaat agcgtcttct ttgttgagtc catctaggaa
     6301 gtctgaatta acgtgaaggc catcttctgt gtaggcagct tcttcaacat ttccaccttc
     6361 aagtacttcg acgattggaa ggtcaaattg tttggcaaat tcccagtcac gttgatcgtg
     6421 ggcaggcaca gccattaccg cacctgtacc atagctagca agaacgtaat ccgcaatcca
     6481 gattggaatt tccttaccat tgacaggatt gatggcataa gcaccagtcc atacaccagt
     6541 tttttctttg gcaaggtcgg tacgagccaa gtctgactta aggctggctt ggtgtttgta
     6601 gtctgctact gcttctgctt gctctgtgct tgtgatggca tctactaatt catgttcagg
     6661 agccaaaaca gtgaaagtcg caccgaaaag tgtgtccgga cgagtagtaa agactgtaaa
     6721 ttccttgtct gttcctttta ctttgaaagt tacattggca ccagttgatt taccaatcca
     6781 gttgcgttgc atatccttga tagactctga ccaatctagt tcatctaagt cattgagcaa
     6841 gcgctctgcg taagccgtga ttttgagcat ccattggcgc attggtttgc ggacaactgg
     6901 atagcctcca cgttcagaag ttccgtcagg aagcacttct tcattggcaa tggcagttcc
     6961 caattcctca acccagttta ctggcacttc agcttcatag gccaagcctt tttcgtaaag
     7021 cttggtgaaa atccattgcg tccacttgta gtagtttgga tctgttgtgt taacttcacg
     7081 atcccagtca taagaaaatc caagcgcatt gatttgacgt ttgaagttgg caatgttttc
     7141 cgctgtaaat tctgctgggt cattaccagt atccatagcg tattgctctg caggcaaacc
     7201 aaaagcatcc caacccattg ggtgaaggac attgtagcct tgcgcacgtt tgtaacgact
     7261 gaggatatcg gttgcagtat aaccttctgg gtgtcctacg tgcagaccag ctccagacgg
     7321 ataagggaac atatcaagcg cataaaactt aggttttgat gcatctgttc ctgtcttaaa
     7381 tgtatgatgt tctgcccagt agccctgcca cttaggctca atttctttat gattgtaaaa
     7441 actcatggtc tctctccaat tttgtgatgt tactattata ccatttttga gggaatttga
     7501 aatgtgttta aaggaaaaac tgtatactgt atctcattaa ttttgatgac tatgaattgc
     7561 tctatctccc actttttatc ccattgttat gcagtaaatc aaggagtaag tcaagacgct
     7621 tatctcgtat agcacaaaat acttatttta gaccgaagat aaaactggaa tgctaattaa
     7681 tgtattcaca ataaatagcc gacaacctat gtcgcttttt gatttatgaa gaacgtatag
     7741 tggactgaat ctgaaatagt acgaaacaat tgctaaaaca ttgttagaaa ttaattttac
     7801 tttcccaatc gatttgttct catcttattt caatctgcta tagaattcaa tacgaggatc
     7861 aataaaagac tatcatttgg aaaacagtag tccttattgt ttattttgaa tttacatagg
     7921 catctacagc gataatagct tgagcaacat ctgaaggcga aatcttaaac ggcatctgat
     7981 gaattgtctc accctccata gttgcttgtt taccaacttt tattaaatca tcatatccaa
     8041 cttgatccaa atgcatttct tttagagttg ttggcatacc aatttttttg taaaactcaa
     8101 tatacttatc aagttcttct ttaggtctat tttccaataa tagttgtact aaagttccat
     8161 aagctacttt ttcaccatgt gttaaatgat gaatgtcacc tgtcaatgca gtaaaaccat
     8221 tatgaattgc atgcgccgca gctaatcctc cactttcaaa acctaggcca ctcaataaag
     8281 tattagcttc aacaatattt tctaatgctg gtgtcaccac tttagcttca caagctgcca
     8341 tagcctgtaa accatctgca aacagcgttt cttcacattt cttcgcaatt gcaactccag
     8401 ccaatgtttg ctgttgtccc aacatagttt ttccatttgc ctgcataacc gcacgcgcct
     8461 caacccaagt tgctaaacca tctgcaatac cagacgctaa taaacgctta ggggcttgtg
     8521 aaataacttt tgtatcaacc aaaactaaat ctggattttt agaataaaat agataatgat
     8581 caaatgcacc ttcatctgta taaataacag ataaagcaga tacaggtgcg tcggtcgatg
     8641 caattgttgg agcaataata acaggctttt caatcaaatc tgcaatagct tttgcgctat
     8701 caatcgtctt tcccccacca agaccgataa tactatcaca attttctttc tcagccaagg
     8761 caacaactcg attgatttca ttgtcagaag cttcaccatt aaatagcgcc agaacaatat
     8821 ggaaaccata cctatgtagg taatcttcaa atcgttttcc aacaatatca taaaccaact
     8881 gatcgcataa tagaataggg caatttccca aatccaaaat tgatttggca ttttcaaaca
     8941 aggcattttc cccctgaata tatctagaag gactagcaaa aattctcata tgtatttcct
     9001 ctctatctaa atggaacgac tattttgaat aacaaaccag tcgtcagaaa agtcatcaac
     9061 cgccttttgg atagatggca tggcgaaagc tgattcaaaa acatctgctc ctgctgtaac
     9121 agcatgcgca cctgcagcta aagcattatt tacttgtgct acatttttaa aggatgcagc
     9181 taaaatctta ctaggagagt tctgtctatc aatagcaaga gctaattgac gaatgacaga
     9241 atttgaatca atgttcagat tttccattct attataatat ggagctaggt aatccgctcc
     9301 tacttcgata gctaataatc cctgaataac tgtataaata gctgttgcag tgatatggta
     9361 gccctctttt tttagcacct ttattgcacg taatccagct ggagtaacag gtactttgat
     9421 aaatatatca tctcctgctt gtcttcgaat ttcatgagca tcctttaaga tgccttcaaa
     9481 atcttgagaa atcacctgaa catgaataga gggtgtagag ccaatcaatt ctcttacatc
     9541 tttgattcgt tcaaaaaaat taatagaacc ctctcttttt gcaatagtgg gatttgaagt
     9601 taccccagct agcggcaaaa tttcagacca ctttttaatc tcatctaaat ttaatgtgtc
     9661 aagcataaat tccataaaaa gaacctcttt attttacaaa gtatgctcag tacgtcctat
     9721 aatgtcatct tgggttgcct tagaaagaac attgaagaat gcagagtatc ctgcaacacg
     9781 aacaattaag tctctgtgtt tttcaggatg tttctgagcg tcaatcaacg tctctctgga
     9841 aacaacattg tattgaatat ggtacccatg taaacgatta aagaatgttc gtaacaaagc
     9901 aattagtttt aatttatctt cttctttggc taacgtttga ggatttactt tctgatttaa
     9961 gagaacccca cctacgattt catctgttgg taattttgaa acagatttta aaacagatgt
    10021 agggccgtgt tgatccatat tatgtgatgg tgaacaaccc tctgctaacg gtgtacccgc
    10081 gttgcgtcca tctggagttg ctaatgttcc acgtccctgc cctacgttgg ctgatataga
    10141 agatgttcct gaataacgaa ttcctccaat aggccctctt ccataacgtg tattaggata
    10201 tttagcaatt tcatcaacat aaatgtcata agcagcagta accaatttgt cagcataatc
    10261 atcatcatta ccatacttag gtgcatcatg aatcaacatt tcttgaatga ccttaccttc
    10321 ttctccggca taatctgttt ccagtgcatg ccaaagctga cttgggctta tacgttcttc
    10381 ctcaaacacc aattttttaa ttgcagctaa tgaatccgac aaatttgcaa ttccaacttg
    10441 caatcctgat atataatcat atactgctcc accttcttta aggtgttttc cacgaccaat
    10501 acaatcatca gtcaatgctg aacatagaat atcaggaact tctcgttcca atgataaatc
    10561 aatagaattt tcaacaataa cactcattcg tgtcaaatat cttagtgttt tatcccaagc
    10621 attttctaat tcagaaaagt tcttcatatc cttaaaatga ccaaagcttg gtgcaaaccg
    10681 tttacccgaa gccggatcaa ttccatcatt catcgtgata agtagaacct tagggaagtt
    10741 catataactc atacctgtgc aacgatagcc ccatttccct ggaactgccg tttcaacaca
    10801 tccaatggca ctgtaatcat aagcatcatc ttccaatact ccttttgcaa taaaagaagg
    10861 aataataatc tcatcattat taaatgcagg cataccaaaa ccaagtttca tcacttcaat
    10921 acactcattc atgaaacgag catctaaacc tgcatggtaa cgtacagtta gattaggttg
    10981 cggtagatgg gtttgtgcaa ctgattttaa taccaaataa gataatgggt taacagcatc
    11041 cttcttatct cgagtctgtc caccaattgt aacattttga tataaaggac ttcctgctga
    11101 agaaaatgta tgtgattgac tgcgaacctt attgattgta attgtcttaa tccaaagatt
    11161 tgtcagacgt tcaacaatgc tatcttctgt ttctttacca ctttctaaat cagccttcat
    11221 atatggatac atatattgat caaaacggcc atatgaaaga gagtggccat tagattcaat
    11281 ttgtaaaata cattgaataa accaaactga ttgaatagct tctgcaaaag tagttgccgg
    11341 ttcatatggg actctagagc aaatatctgc aatctcaagt aattctttct tacgtttagg
    11401 atttgcattt tcggctaaac ttttagcaag agcaacaaag cgctttgcat atactttaat
    11461 agcatcgatt acgataaata tagagtcgta aaaatgatat ttatcaatac ttgctgaatc
    11521 tgttaaatct agagctactt ttgctttacg agcccgctct tcaaaacctc ttaaaccaaa
    11581 ttgcaaaagt ttctgatagt taactgctaa gtgagcatct ccagaattca tcttaccttc
    11641 cataccgaag aatcctgttt ccatataaac agacacttct tcaggtaata aggcaccagc
    11701 tctagcacgt aaattattat tttcccaaaa cggagcaata cttctaagtt gttcttttgt
    11761 ttcttctgta atatagaaaa catctccatc acgcttttca aaaagctcca actcattgag
    11821 aacaaattct agcgtatatt ccggaaaaat aggagcatct ttattggaag aagcttgatt
    11881 tcccgcaatc atagattctt cttcaatata gatagacata ttttccaaaa tttctttcag
    11941 catatatgca cgttttagga cattaggttg ttccttgtat cgttcatagg cgcgtgttgc
    12001 tagaactgct ctctcagcat caatataagg ttttttattt aagacatctt ctcgatattt
    12061 gttcatcctt tcagtaaggc tgccaaaata ttctgtcttg attgttgttc ttgctacttc
    12121 tgtatttacc atcgtaagca cctttctttc gaaaatattt ttatttcttt cgaaaatata
    12181 ataccgattt ttatagaaat tttcaagctt ttaactagaa aaattttaac tctctaattt
    12241 ttagcacaaa tgtatgagtt taacagtaac acacaaatac ctctaagatt atttgatttc
    12301 attttggtaa gctaaacgat cctgtatctt aaagaatgga aagtaaacca atgtagacat
    12361 cgctaatatc accagctgag taataactcc ttgccatcca cccaccaaga atcctgatag
    12421 aatagctggt gtactccaag gcaatgttac ccctgagaat ggctgcatga aacctgttgc
    12481 aatagatcca tatactatcg cagctgcaag tacaggaaca agaatgaaag gtacaaacat
    12541 aactggattc atgacaatcg gaaatccaaa tacaactggc tcatttacgt taaatattgc
    12601 tggaaaagct gcaacttttc ctaaggcttg gtattgtttt gattttgctg caaaaagcat
    12661 ggcaactaca agaccaaacg taatccctga acctgataga attaaaaatg aatctaaaaa
    12721 ctgttgagta acaatatgtg ctccattttc taatgataga ttagcagagg ctaacatagc
    12781 tttattagca tcaagattag ataaaagaag agctgtcact actccattta ctaccgattg
    12841 cccatgaaca ccaaaccacc acaaaaatga tataaagaat gcaattccaa tagcaccata
    12901 caaagatcca gttaaacctt gcaacggaac ttgaatagca gaataaatca tttctatgaa
    12961 tgtcccgcca ttagtcaatg agctcgctaa aatatataca atcatagaag ataagaaaat
    13021 tacaaatgct ggaatcattg tttcaaactg tttggcaata gcttgtggaa cttgttctgg
    13081 catcttaata acaatttttc tctttataaa gaaggtataa atacttccta ctaccaaacc
    13141 tataatgata gcaccgataa ttccctggcc tccaaaccaa actttactaa tagcgtcccc
    13201 aatcgcctca ccttgtttag ggatataaga tgatcttagc aaaataaaga atgcagatac
    13261 agatagaact ccagctggta aagcctctac tccgctattc ttagcataag aataggcaat
    13321 tgaaaaacaa gaaattagac ccataatagc aaaagttcct gaatatactt gcataaacgg
    13381 ctctgtccaa ttagctccaa aaacactagc aatgctctta tttaatcctt cgaacggcaa
    13441 ttgtcccata atcaagaata aactaccaac tactgtcaat ggcaaaattg ctaacatccc
    13501 atcttttaga gctataatgc cacgcatatt cacaaacttc atcatcggtg caatgatttt
    13561 ctgaacatcc atctttgcca taataaatct ccttttctta cccactaatc aaagataggg
    13621 ccaaatctaa tacttttttc ccatctaaca taccatagtc catcatcgga ataacagcta
    13681 tcggaacatc acacttatca caaatttctt ttgatttatc taatgtataa gcaacttgtg
    13741 gacccaatag tgcaacatct atatttggcg cataatccgc taatttagac tgagaaaacg
    13801 cctctatttc tgcctcaact ccactagatt gcgctgcaat tttcatatta tttacaagca
    13861 taccagtaga aaaacctgct gcacaaaaca aaccaatctt caccattatg ttttcctcct
    13921 ctatgttaat aacaatgata atactctagt attatttttt atgaagttct tttctcaaac
    13981 taataatttc tttgattaaa ttaatctccg tcatactagt catgagatga tcttgtgaat
    14041 gaacaaagag agctgtaatt tctgtctttg taccagacgc ttcttgtgcc aagaattttg
    14101 tttgtagatt atgggcttct aataaggcgg catcagctaa ctggatttct tcttcacacc
    14161 gttcacatgt accatttttt atgtaatcta acgctttata aatatgttgt ttcgcatcac
    14221 cagcatataa aattaaaccc atgataattt gatctggaac aataatttcc ataaattcct
    14281 cctcatttca ctatgtaaaa agcttttttc atttgaaatt ttaaaatttt cttttgtaac
    14341 tatagaatac aactacataa taaagttgtc agtccaaaaa caacagataa actatttttg
    14401 tttatataag cacaaatgtg caatcaacta aaaagaaaaa cgataaact
//
LOCUS       DAVDHZ010000053        14281 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000053 DAVDHZ010000000
VERSION     DAVDHZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.054"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(43..2409)
                     /locus_tag="VUR46_001914"
     CDS             complement(43..2409)
                     /locus_tag="VUR46_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET5457275.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLTQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLINDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     IEEKQQAVSETVTSSISEQSYILTEENWDSIPAMIGITDADLKEIFGK"
     gene            complement(2537..3151)
                     /gene="lepB"
                     /locus_tag="VUR46_001915"
     CDS             complement(2537..3151)
                     /gene="lepB"
                     /locus_tag="VUR46_001915"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET5457276.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQSFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            complement(3163..4035)
                     /locus_tag="VUR46_001916"
     CDS             complement(3163..4035)
                     /locus_tag="VUR46_001916"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET5457277.1"
                     /translation="MASITLTPSKKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKDVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSIIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            4122..4424
                     /gene="zapA"
                     /locus_tag="VUR46_001917"
     CDS             4122..4424
                     /gene="zapA"
                     /locus_tag="VUR46_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET5457278.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSSDDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            4421..4969
                     /locus_tag="VUR46_001918"
     CDS             4421..4969
                     /locus_tag="VUR46_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET5457279.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            5073..7409
                     /locus_tag="VUR46_001919"
     CDS             5073..7409
                     /locus_tag="VUR46_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET5457280.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTDKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRGVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGVFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLASEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDDRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKHVNVVKRTSGRGPQARLDLRGKRYEEAMNELDAFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     regulatory      7573..7661
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            7752..9074
                     /locus_tag="VUR46_001920"
     CDS             7752..9074
                     /locus_tag="VUR46_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET5457281.1"
                     /translation="MLELLKSIDAFVWGPPLLILLLGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDQGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPATIALVFTSAFSPLAVVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     gene            9292..9840
                     /locus_tag="VUR46_001921"
     CDS             9292..9840
                     /locus_tag="VUR46_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET5457282.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKANNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLT
                     ILCNYANNLANTPINPELQPYA"
     gene            9950..10849
                     /locus_tag="VUR46_001922"
     CDS             9950..10849
                     /locus_tag="VUR46_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET5457283.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIADFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(10874..12148)
                     /gene="serS"
                     /locus_tag="VUR46_001923"
     CDS             complement(10874..12148)
                     /gene="serS"
                     /locus_tag="VUR46_001923"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET5457284.1"
                     /translation="MLDIKRIRTDFETVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQTRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(12362..12733)
                     /locus_tag="VUR46_001924"
     CDS             complement(12362..12733)
                     /locus_tag="VUR46_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET5457285.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            complement(12736..14100)
                     /locus_tag="VUR46_001925"
     CDS             complement(12736..14100)
                     /locus_tag="VUR46_001925"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET5457286.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIMVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSRIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
BASE COUNT         3909 a         2954 c         3177 g         4241 t
ORIGIN      
        1 ataaacaaaa agcccacctg aattggtggg ttttcttatg cactattttc caaaaatctc
       61 tttgaggtct gcgtctgtaa tcccaatcat ggctgggatg ctgtcccagt tttcttcggt
      121 taggatgtag gattgttcag agatacttga tgttactgtt tcagagacag cttgttgctt
      181 ttcttcaata ttctccagta gatcactgaa gcgttcaatc agataggttt ttcgggcagt
      241 tccgatgtgt tgggtagcat agtcgaaggc ttgtaattcg cctagtaaga tgagtttgct
      301 cttggcacgt gtaatggctg tgtagatgag atttcgctcc agcatacgtc ggctagcact
      361 agtaatcggt aggatgacaa ctgggaactc acttccctga gatttatgaa tactcatggc
      421 ataggccaag cgaatcttgt accattcgtt acgggggtaa gagacttcat taccatcaaa
      481 atcaatgaca atctcgtctt gtttcgattc ggtgtattta ccaggaatca ggtctgtgat
      541 agctcctaaa tccccattaa agacattgat ttcagcatcg ttaatcaaat gaatgacctt
      601 gtctccctta cgatagtggc actgaggagc ttcaaaactg agttgatctt tttgtggggg
      661 attgagcagg tcttgcgtga gttgattgat agcatcaatc cctgccgtcc ctcggtacat
      721 aggagccaga acttggatat cacgggcagg gataccattt ctgagggcgg cacctaagat
      781 tttttcaatg gtggcaggaa tatggccact agcaatttca aagtaggaac ggtcagcttt
      841 tttttgggtg aaatcagctg gcaagatgcc ctgtcgaatc tgactagcta gggtgacgat
      901 ggttgattct tcgctttgtc gataaatttt ttccaagcga gtctgaggaa tcaagggaat
      961 atgaagcaga tccgctagaa cctgtccagg gctgacagaa ggcaactggt cgctgtctcc
     1021 cacgatgagg atcttactgt tagaagagat gttggagaag agttgattgg ccagccaagt
     1081 atccaccata gagaattcat ccacgatgat aaagtcagca tctaggtaat cttccagatg
     1141 actggtatca tcgtcacctg tcattcccaa gtggcggtgt atggtcgcgc taggcaaacc
     1201 tgtcaattca ttcatgcgac gagcagctcg accagtcgga gcagcaagaa gaatgggcag
     1261 attgcttttc ttcctgaagt caagtccttc taaaagggca taaacagcga tgattccatt
     1321 gataacagtt gtcttaccag taccaggccc acctgtcagg ataaagacct tgttctggat
     1381 agcgtcacaa atagcttgtt tttgaatgtt atcatactca atccccagtt cttgctcgac
     1441 agtagtgata tgcttttgaa tagtttctaa atcttggctc ttctgttttc ctttttcaag
     1501 gatacgaatc aagtgactgc ggataccttc ctcagcgaaa aagaggctgt tgtcaaagat
     1561 cttggtatca atctgctgaa ccttgtcttc ttcgatcagg taggagagct cttgggcaac
     1621 ttggctgggg tctagttcca cgggacggga agactcaagg agagtaaggg tttgttccag
     1681 caaatcccgt gcttcaacat aagtgtctcc tgtttccata caggcctgaa aaagactgtg
     1741 aactagaccg gcgcggaagc gttcaggagc ctgactttcg atgcctagtt cctcagctag
     1801 ttggtcagca atggtaaagc ccaaaccctt gatatcctca accagctggt agggataatt
     1861 ttcaaccaca tcaagggttt cttccttgta aaagtcttga atctgaaagg ctagtttgtt
     1921 gggaatgccg tagttggcta gtttggacaa aaccatctcc gttccgtagt tgagacggag
     1981 agtggagacg aaagcctcgc gatttttggc agagagtcct gcgatgcctt ctaacttttc
     2041 tgggtgttgc aaaatttcgt caatggtatt ttcgccatag gtatctacga ttttctgagc
     2101 tgtcttgaga ccaatcccct tgaaatggct acttgaaaag tacttgacca agcccttact
     2161 agttggtttt gcgcgatcat aacgactaat ttgcagttgt tctccatact tggagtgctg
     2221 gacaatttgc ccccaaaaag tatagtcttc gccctcaatt acatcagcca tggttcctgt
     2281 gacaatgatt tcaaaatcat caaaatcctc tgcgtccgta tcgtcgattt ctaggaggag
     2341 gatgcgataa aaattgctgg gattttcaaa aataatccgt tcaatggttc ctgaaaaata
     2401 aacttccata aaattccttt gcatgaatag gtgagagttg aggtgtttct gttctggtaa
     2461 gtttagatag ttaccaatca ttttctcacg atagaagaag aggctgagat tggtgattct
     2521 cggcctctta ggtctcttaa aatgttccga tacgggtgat tggccagaag cggaatttag
     2581 cttcccctgt gatatctttt gctttgaagg tacctacgtg gcggctgtcg ctcgaaacca
     2641 agcggtcgtc tccaaggaga aggtattctc cttctggaac tgtaaagcta aagttggtat
     2701 tgtagttgac atcaactgtg aaggattgag ctttttgagc gatacttcta aagaaagttc
     2761 ctttatttcc ttcaaatccc ttgcctgagt aggtgctttg gagtttgtcg tccttgaagc
     2821 gtttgatata gtctgctaga taaggttcgt ccgtttcttt gtcattgatg tagagtttat
     2881 cattttcgta acggatggta tcgccaggca ttccaatcac gcgcttgacg atgtccttat
     2941 tgccatcttc ctcatgggcc accacgatat caaaacggtc aatagggagg tgcttaacaa
     3001 caaagaggat ttcaccatcc gctagggtcg gatccatgga atgtccttct acgcgaacat
     3061 tgctccaaaa aaagatacgg ctcaaagcta gtaatgatag aatcaggagg aataatcccc
     3121 actcttttaa gaaattttta aataaattca taacttacct ttctaagcgt ttttcgcttt
     3181 ttcagtattt ttaaagtgta gcttagcgca gaagttgagt ccctgcatac cataagcttg
     3241 caaaatctgg ctagccacct tgtcagaagc cgttccagct ccacttggaa gctgataacc
     3301 cagttctcgt cccaaatttt caagattttc cagaaagaga tcacgcgcaa tgatggaaga
     3361 aactgcaaca gccaagtatt tgccctcagc cttttcttct aagctgatag gattgctgaa
     3421 acgattggcc tcttgtgcca agtacttgtc ataattttta gcactggtaa aggcatcaat
     3481 cacaattttc tcaggctgaa catctttttg aaggaggaga tagatagcct gattatggag
     3541 ggcaacctta accgaaacag cattgtagcg gtctccgatg acctcgttgt acttgctggg
     3601 tgagagaagg agtgcctggt gctggatttt ttccttgaga ataggagcaa tctgacggat
     3661 cttttggtcg gtcagagtct tagaatcccc cacaccgagt tttcgtaaaa agtcgtgctg
     3721 gtcaggtgtg acaaaggcag ccacaactgc aagcccacca aagtaggaac catttcccac
     3781 ctcatctgtc ccaattaaag gaagattttg tccgctggtt tgctctacag cttgatagcc
     3841 aaagaaactg gcgtattttt cagccccttc accctgaagc aagatttttc cagaagtata
     3901 gatagaaacc gttgcttgag gtagtttcaa aaagtagcgg atatagggat tcttgctagg
     3961 agccagactg gtttgatagt gttcaagaaa agcctgaata tcctttttgc ttggtgtgag
     4021 tgtgatactt gccatagttt ctattgtacc ataaaagcag taaaatttgt aaaaactgac
     4081 aaaattagcg aattttggta taatatcgtg aggtgaattt tatggcaaat ctaaatcgat
     4141 tcaaatttac attcgggaaa aaatcgttaa ccttgacaag cgaacatgat aaccttttta
     4201 tggaggaaat cgctaaggtt gcgacagaaa aataccaagc aattaaagaa caaatgccta
     4261 gctcagatga tgaaacaatc gctcttttgt tggcagtcaa ctgtttatca actcagctca
     4321 gccgtgagat tgaatttgac gataaggagc aagagctaga agaactccgt cacaagcttg
     4381 tgacttgtaa gcaagaacag agcaagattg aggattcctt atgatttcat tccttcttct
     4441 attggtcttg gtttggggat tttatatcgg ctatcggaga ggcctgctct tacaggttta
     4501 ttacctgatt tcagccatgg catcggcttt tatggctggc cagttttata aggggcttgg
     4561 agagcaattc catttattgc tcccttatgc aaattcgcag gaaggtcagg ggactttctt
     4621 tttcccatcg gatcaactct ttcagctgga taaggtcttt tatgcaggta tcggctactt
     4681 gcttgtattt gggattgtct atagcattgg tcgtttgctt ggtcttctct tacacttgat
     4741 tcctagcaaa aaactgggtg gtaagttgtt ccaagtttca gcaggtatct tgtccatgtt
     4801 ggtgacctta tttgtcttgc aaatggcctt gacaatcttg gcgaccatcc ccatggcagt
     4861 tatacaaaat cctcttgaaa agagtatcgt cgcaaaacac atcatccaga gcataccgat
     4921 aacaaccagt tggctcaaac aaatctgggt gacaaattta atcggataaa aagggcagga
     4981 gttttcctag ccctttgttt acagatttga ctcgaatcta tcagaatgta aaaagctacc
     5041 acacctagac attcaaagac aaggaaataa agatgaataa gaaaatatta gaaacattag
     5101 agttcgataa ggtcaaggcc ttgtttgagc ctcatttgtt gaccgagcag ggcttggagc
     5161 aattgagaca gctggctccg actgacaaag cagataaaat caaacaggct tttgctgaga
     5221 tgaaggaaat gcaggctctt ttcgtcgagc aaccgcattt tactattctc tcaactaagg
     5281 aaattgcagg agtctgcaag aggttggaga tgggagcgga tctcaatatc gaggagttcc
     5341 tactcttgaa acgcgtgctt cttgccagcc gagaacttca aaatttttac gccaatctgg
     5401 aaaatgtcag cttggaagaa ttagcccttt ggtttgagaa attacatgat tttccgcaat
     5461 tacaaggaaa tcttcaggcc tttaatgatg caggcttcat tgaaaatttt gccagtgaag
     5521 aattggcgcg aatccgtcga aaaatacatg atagcgagag tcaggtacgc ggtgttttac
     5581 aagacttgct caagcaaaaa gcgcaaatgt tgacggaagg aattgttgct agcagaaatg
     5641 gccgtcaggt tttaccagtc aaaaacacct accgcaataa gattgcaggt gtcgttcatg
     5701 atatttctgc tagtggaaac accgtctata tcgaaccccg tgaggtagtc aaactgagcg
     5761 aagaaattgc tagtctgcga gcagatgagc gctatgaaat gcttcgcatt ctccaagaaa
     5821 tttctgagcg tgtccgccct catgcggctg agattgctaa tgacgcttgg attatcggtc
     5881 atctggactt gattcgtgcc aaggttcgat ttatccaaga aagacaagca gtcgtgcctc
     5941 agctgtcaga aaatcaagag attcaactgc tccatgtctg ccatcctttg gtcaaaaatg
     6001 ccgtcgcaaa tgatgtccat tttggtcaag atttaacagc tattgtcatt acaggtccca
     6061 atacaggtgg gaagaccatc atgctcaaaa ctctgggctt gacacaggtc atggcccagt
     6121 caggattgcc gattttagca gacaagggaa gtcgtgttgg tgtttttgaa gaaatctttg
     6181 ctgatattgg agatgagcag tctattgagc agagcttgtc taccttctct agccatatga
     6241 ccaatatcgt ggatattctt ggcaaggtca accaacattc actcttactt ttggatgagt
     6301 tgggggctgg tactgatccc caagagggag cagcccttgc catggctatt ctggaggacc
     6361 ttcgcctgcg tcaaatcaag accatggcga cgacccacta tccagaactc aaggcctacg
     6421 gtattgagac agcctttgtg caaaatgcca gtatggagtt tgatactgca actcttcgcc
     6481 cgacctatcg ctttatgcag ggtgttcctg gccgaagtaa tgcctttgaa attgccaaac
     6541 gtctaggcct atctgaagtt atcgtaggag atgccagtca gcagatcgat caggacaatg
     6601 acgtcaatcg tatcattgag caactagaag agcagacgct ggaaagccgc aaacgcttgg
     6661 acaatatccg tgaggtggag caagaaaatc tcaagatgaa ccgtgcgcta aaaaaactct
     6721 acaacgagct taatcgtgaa aaggaaaccg agcttaacaa ggcgcgtgaa caggctgctg
     6781 agattgtgga tatggcccta agtgaaagtg accagattct caaaaatctc cacagtaaat
     6841 cccaactcaa gccccacgaa atcattgaag ccaaggccaa gttgaaaaaa ttggcttctg
     6901 aaaaagtgga cttgtctaaa aataaggtcc ttcaaaaggc caaaaaaaaa cgagctccaa
     6961 aggtgggaga tgatatcgtg gttctcagtt atggtcagcg tggtaccttg actagtcagc
     7021 tcaaggacga ccgctgggaa gcccaagttg gcttgattaa gatgaccttg gaagagaaag
     7081 agtttgacct tgttcaagcc cagcaagaaa aaccagtcaa gaagaaacac gtcaatgttg
     7141 tgaaacgaac ttctgggcga ggacctcaag ctagactgga tcttcgaggc aagcgctatg
     7201 aagaagccat gaatgagcta gatgccttca tcgaccaagc cttgcttaac aatatggctc
     7261 aagttgatat catccatggt atcggaacag gagtcatccg tgaaggagtt accaaatact
     7321 tgcaaagaaa taaacatgtc aagagtttcg gctatgcccc acaaaatgct ggaggcagtg
     7381 gtgcgactat tgtcactttt aaaggatagc agtattctgg actttataaa gtaaaaactg
     7441 ttgaactaat ttttactaat aaacacattg acaaaagcca acattttttg taaaattaga
     7501 atcaattaaa taccaacacc gaatgaagtt taatagaagt ggggaatcgt ttgattttcc
     7561 atgactgtaa atggacggaa ctctggagag accgtaaagg caccgaaggg gcaaggcagg
     7621 caactgctca aactctcagg taaaaggaca gagctaggat agacggcttt ttagcattta
     7681 tctaagcatt ccagagtaca tgtatcttgc atgtgctctt tcttttgggg ttgaaacgat
     7741 aggagaagga aatgttagaa ttgcttaaat caatcgatgc ttttgtttgg ggaccgcccc
     7801 tcttgatttt attgctcgga acagggattt acctaactat tcggctagga ctcttgcagg
     7861 ttttgcgtct gcccaaggcc tttcagctta tttttatcca ggataaggga catggtgatg
     7921 tatccagttt tgcagctctg tgtacagcct tggcatcaac tgttggaaca ggaaatatca
     7981 taggagttgc gacggctatc aaggttggtg gaccaggagc tctattttgg atgtggatgg
     8041 cggctttctt tggaatggct accaagtatg cggaaggact cttggccatc aaataccgca
     8101 ccaaggacga ccaaggtgca gtagcgggag gtcccatgca ctatatcctt ctagggatgg
     8161 gagaaaagtg gcgaccactt gctgttttgt ttgcagtagc aggagtattg gttgctctct
     8221 tgggaatcgg aaccttcacc caagtcaact cgattacaga atctatccaa aatacaacga
     8281 cgatttcgcc agccatcaca gctctcgtct tgtctgtctt tgtagcgatt gcagtctttg
     8341 gtggactcaa gtctatttct aaggtttcaa ctactgttgt tccttttatg gccatcattt
     8401 atatcttagg aactcttaca gttattttct ttaatatcgg aaaaatccct gccacaatcg
     8461 ctttagtctt tacctcagct tttagtcccc ttgctgtggt aggtggattt gctggtgcta
     8521 gcgttcggat ggctattcaa aatggtgtgg cgcgtggtgt gttctcaaac gaatctggtc
     8581 taggttctgc tcctattgca gctgcagctg ccaagacaaa tgaaccagta gagcaaggtt
     8641 tgatttccat gacaggaacc tttattgata ccctcatcat ttgtactcta actggtttga
     8701 ccatcttggt aactggagtt tggagtggtg acttgaatgg ggttgccttg actcagtcag
     8761 ctttctcaac agtcttttca cactttgggc cggccctctt gaccatcttc cttgtacttt
     8821 ttgcctttac aacgattcta ggttggaact attacggaga acgctgtttt gagttcctct
     8881 ttggggttcg ctttatctgg ctctaccgtg tggtttttgt gctcatggtc ttgttaggag
     8941 gatttatcga gttggatatg gtctggatta tcgcagatat cgttaacgcc ttgatggctc
     9001 tgccaaactt gattgccctc ttggtcttgt cgccagtcgt tattgctgaa actaaaaagt
     9061 attttgacaa ataatggaat cacacagctc gtgtgatttt tttgcctata aataattttt
     9121 atcagcctga tatataatat atattataca agtgattgga agtgtgataa actaatataa
     9181 caacgaaaat cttatgagag aataaagctt tatcttagat aaacttagga atcaggattt
     9241 tataagattt tccaataata ttagtgtcaa taataagaaa agaggtatct tatgacaaca
     9301 tttactatcc atacagtaga gtcagcacca gcagaagtga aagaaattct tgaaacagta
     9361 gaaaaagcca acaatggcta tattcccaac ctaatcggtc tcttggccaa tgccccgact
     9421 gttttagaag cctaccaaat tgtctcatct atccaccgtc gcaacagtct gacacccgtt
     9481 gagcgtgaag tggtgcaaat cacggcagcc gtgaccaatg gttgtgcctt ctgtgtcgca
     9541 ggtcacacag ccttttccat caaacaaatc cagatgaatg atgacttgat tcaagctctt
     9601 cgcaatcgta ctccaattga aacagatcct aaattggata cactagctaa gtttaccttg
     9661 gcagttatca ataccaaggg tcgtgtagga gatgaagcct tgtctgagtt tttagaagct
     9721 ggctacactc aacaaaatgc cttggatgtg gtttttggtg tcagcctaac aatcctctgt
     9781 aactatgcca acaacttagc taatacacca attaatccag aattgcaacc ttatgcctaa
     9841 ttcatatctg agtaaaatga agtctgaaat aagcggactg cgttttttta aatcctcatt
     9901 taagcgcttt tatgttatac tgaaactaac atgattattg gaggttagga tgaaaaaact
     9961 ccccttagta ttttcaggtt gtttgctagg tttggcagga gctggaaatc ttattttaga
    10021 tacgttgccg gttctatccc atctttttag tctgactggt ttggttttat ggatttactt
    10081 tctaattctg catctcttta attggaaaga aaccaagcaa gaattgacca agccccctct
    10141 tttgtcagga atggcaacct ttcctatggc tgggatgatt ttatcgacct atgtctttcg
    10201 cgtattctct tatcttcctt tggtagcaca agggatttgg tggttttcat ttctcttgga
    10261 tttgaccttg attgctgact ttaccatcaa gtttgcttgt ccagggcgga gggttcatgc
    10321 cactccaagc tggacggttc tctatgtggg gatagcagtg gctgccttga cctatcctct
    10381 ggtaggtatt atcgaaattg cctatgcgac cttgagtttt ggttttctct tgaccttcta
    10441 tctctatccc cttatttata gcgatttaaa gaaacatcca ctcccactag ccttgcttgg
    10501 acaagaagga atctactgtg ctcctttctc tctactcttg gcttctctag ttcgagtagg
    10561 aggaaccagc ctgccgactt gggtcttgat tgtcatgatt ttggcttctc aatccttctt
    10621 tttctttgtt ttaactcgtc tgcccaacat tttaaaacaa ggttttcaac cagccttctc
    10681 agccctcacc ttcccaacca ttatcacagc gacctcgctc aagatggctc agggaatttt
    10741 gaaacttcca tttctggatt acctggtatt gactgaaacc attatatgcc taactatttt
    10801 attctttgta ctaggtgctt atctgatttg gttacgaaaa aaggtctagc tagaaatagc
    10861 taaaccttat tttttatggt ttgatgactt cagctccacc catgtatgga cgaagtgctt
    10921 ctgggatggt cacagaacca tcttcatttt ggtaattttc aagaattgca gccactgtac
    10981 gtccaactgc aagtccagaa ccgttcaagg tatgaaggag tttcaccttg ccatctgctt
    11041 catcacggta acgggtttgg gcacgacggg cttggaaatc ttctgtgttt gaacagcttg
    11101 agatttcacg gtaattgttt tgtgctggaa tccacacttc caagtcgtaa gtcttcgcag
    11161 ctgagaagcc catatctcca gtagagagag caacgacacg gtatggaagg ttgagttttt
    11221 gaagaatgtt ttcagcgttg gctgtcattt tttccaattc ttcgtaagat tcttctggtt
    11281 tggcaaattt gaccatttca accttgtgga attggtgcaa acggatcaag ccacgcgtat
    11341 cacgaccggc agaaccagcc tcagaacgga atgacggact catagcagtg aagtagattg
    11401 gaagatcttt gccgtctaag atttcatcac ggtagtagtt tgtcagagga acttcagcag
    11461 ttggaatcaa gacaaagttg gtatcgctga gttcaaaagt atcttcctta aattttggat
    11521 actgaccagt accaaacata gaatcatggt tgactatgta aggtgtgatg acttcagtat
    11581 agccttcttt tccatgttca tccaacataa agttgtagat agcacgttcc aaacgagcac
    11641 cgaggccttt atagaagagg aagcgagcgc ctgttacctt accaccgcgt tcccagtcaa
    11701 ggataccaag gtcttcaccg agatcccagt gagctttagg ttcgaagtca aactcgcgtg
    11761 gagtacccca acggcgaact tccacattgt cgtcttcgtc agccccaaca ggaacgctgt
    11821 cagctgggat atttggaaga gtcgttgtaa attctgtcaa tttagcatcg atttctgcca
    11881 attcagcatc caaggcttta acctcagcag atagattttg catggcagca atcttgtcat
    11941 ctgtattttc cttgttgcgc ttagcttggg caatctcagc agaaactgtg ttacgttctg
    12001 ctttgagagt ttcaaccttg accaagatgt tacgacgttt agcatcgatt tctttcattt
    12061 cattcaagac agcagcatct acaccacgtg tagctaattt ttctgcgaca gtttcaaaat
    12121 ctgtacgaat acgtttgata tctaacataa gaactccttt atgaaaaaag cacgcctgac
    12181 aaaacgttgg agtggcaggg ccacggttcc atccaacttc acaggtgtgc acttgattgt
    12241 gtatgtaatt gttactaacg gtagaatttc acctatccct cctatctgct cgcagtaccc
    12301 gcagactttc tgaaagaaga agataaccta cttatccgtt gctatgatta tactaaagtt
    12361 tctacttttt tgcaaataga tttttaaatt tttggctaat tgtctgaatc agggtcggaa
    12421 gtttgacgac cttgtcattg cctagttttt cgcgtgcaat tttgagaatg gcacctgagt
    12481 cttttgaagc aaagaggaat tttcctttgt ctgtaaagac ttcgaagtgg cggctgattt
    12541 tgcgtccagt gacattggct ccaatctgat tgatatggct ccaaggaatc tggataaatt
    12601 gttcgacatt gacatctggg taaaattcca aagcctgatc tccgacaagg aatttcccaa
    12661 ctttcccagc gatagagagg taggaagtgc ctgtcgtact gaggagtact gttttgttaa
    12721 gtgattgggc catgcttagt cttccttact ttctccaaaa aaggcattgt agagggcttt
    12781 aattgctgct ttctcttggt ctttattgac aacaaacata atagaaactt cactagaacc
    12841 ttgagacatc atctggatgt tgattttgtt ttcagataga gcgcgtgtcg cagtagcagt
    12901 cactccgata cggctcttca ttttttcacc aacaatcata atgatagaaa ggtcgtgttc
    12961 gatttctgca tgatctactt tagccttttg aaccaactga cgcaggattt cttcttcctt
    13021 gatgggagtt agttggcgag aacggagaat gatagaaaga tcgtcgatac ctgttggcat
    13081 atgttcccaa ccgatgttaa gttcttccag gatttgcaga accttgcggc caaatccaat
    13141 ctcacggttc atgaggtatt tcgacatatt aatgctgaca aagcctgagt caccagcaat
    13201 tcccacaact ggaaattcat cattactgtg ttttagaacg atacgagtac ctggatggtc
    13261 agggttgttg gtattcttga taaccagagg aatttttcca cggtaggcag gaagaagagc
    13321 ctcgtcatga aggactgaga agcctgcata ggccaactcg cgcatttcac ggtaggtcaa
    13381 ctcaggaatc gagtgtggtt ggtggataat accagggtgg gctgcaaaga taccatcaac
    13441 gtccgtaaag ttttcataga ggtcagcttt gacaccagca gcaatgatag aacctgtaat
    13501 atcagatcct ccacgtgaga aagtacagat ttgattttcc ttagtgacac caaagaaacc
    13561 aggaatgaca aggacttcat tggtgtttgt caattcttca atcttgtcat aacttgatgg
    13621 aatgatgcga gcgtgaccag gttcacttgt gaccataatc ccagcttctc tagggtgcat
    13681 atagcgtgca tcaataccat tttggttaaa gtaggcagca atcaatttgg cattgttatt
    13741 ttcaccggct gctaggaaag tatcgtagag aaattcattt tcttcaatag gaagagtggc
    13801 caaggcgtga atgcttttag aaattttttc tagcacagct ggttttagtc ccaattcact
    13861 aaccatagca gcatagcggt cgataatcca gctttggctc ttgctaatat cgttacccgc
    13921 aacatagtcg cggtagtatt taatcagggc atccgtaacc ttagtatctt cagcattgcg
    13981 tttaccaggc gcagaaacga ctacaaaacg acgctctgaa tcgcttttaa cgatatttaa
    14041 aactttttct aattgactag cagaggcaag agaactacct ccaaatttaa caactttcat
    14101 aagaactcct aaagtaagta ttctatacga ttatagcaga aagaaaggct tttttcaatg
    14161 aagaaaatgc aatcttgttt gggtgaaaaa tgacaagtat tttgataata acttgccaac
    14221 atctatcact tatcggaatg ttaaaaaagt tagcgttttg ctgttcaaat ttgtaaaaat
    14281 a
//
LOCUS       DAVDHZ010000054        13790 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000054 DAVDHZ010000000
VERSION     DAVDHZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13790
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.055"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..977)
                     /locus_tag="VUR46_001926"
     CDS             complement(<1..977)
                     /locus_tag="VUR46_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PavB family fibronectin-binding SSURE repeat
                     adhesin"
                     /protein_id="HET5457287.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVVSGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLPETQGDTVLTEVKPEVVAGNTNSLSTPTEGTEVSEET
                     SPSRLDTLFEKGEETQENPELTDVLKKAVDTADVDGTQASPEDIKKAVDEDVNDTIDV
                     PAAYLEQAKASGPFLAGVNKPLKYELFAGDGMLTRLLLKASDKAPWSDNGVAQNEKIP
                     PVKNLPDGKYYYQVSLNGNTEGKKDQDLLDTLRTNGTNTYEATLTVYEADGDKPDLTK
                     VVKTRNVNITLNGLVTKSDVKSAVENNVKDSIDVPAAYLEQAKGEGPFTA"
     gene            complement(1093..1503)
                     /locus_tag="VUR46_001927"
     CDS             complement(1093..1503)
                     /locus_tag="VUR46_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET5457288.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQENPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            complement(1570..2112)
                     /locus_tag="VUR46_001928"
     CDS             complement(1570..2112)
                     /locus_tag="VUR46_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5457289.1"
                     /translation="MRKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQ
                     TQEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLK
                     ILKTLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKG
                     QYIMMHSLIYRTDLLRASQF"
     gene            complement(2418..3083)
                     /locus_tag="VUR46_001929"
     CDS             complement(2418..3083)
                     /locus_tag="VUR46_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET5457290.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQNMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(3097..4476)
                     /locus_tag="VUR46_001930"
     CDS             complement(3097..4476)
                     /locus_tag="VUR46_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET5457291.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTYFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            4694..4981
                     /locus_tag="VUR46_001931"
     CDS             4694..4981
                     /locus_tag="VUR46_001931"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457292.1"
                     /translation="MKTKASIRELVTGCSKHCFEIVDRTDEVSSKHCFEIVDRTDEVS
                     SKHRFEVADRTDEVSSKHCFEVVDRTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            complement(5221..5985)
                     /locus_tag="VUR46_001932"
     CDS             complement(5221..5985)
                     /locus_tag="VUR46_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET5457293.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(6202..6759)
                     /locus_tag="VUR46_001933"
     CDS             complement(6202..6759)
                     /locus_tag="VUR46_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HET5457294.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLYPLDPQERNSGIEYGKPITIGDNFWTGGGVIVFPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            complement(6865..7719)
                     /locus_tag="VUR46_001934"
     CDS             complement(6865..7719)
                     /locus_tag="VUR46_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5457295.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            complement(8075..12925)
                     /locus_tag="VUR46_001935"
     CDS             complement(8075..12925)
                     /locus_tag="VUR46_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5457296.1"
                     /translation="MSRKSIGEKRQSFSMRKLSVGLVSVTLASFFLMSQGIQSVSADN
                     MESPIHYKYMTEGELTDEEKSLLVEALLQLAEESDDTYYLGYIKTKKQDNAGISRTVD
                     GKYSARSDSQPDSTKISDVVHSADSEWSQGQGKVSLQGEASGDDGLSEYTDPVATKGT
                     QEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKIERQGQAGT
                     RTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLTKVENKKSI
                     TVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPYTVKTHLTY
                     NLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSEAPTDTAKY
                     FVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTFTVAKSKVE
                     QPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTGSLIGSDGT
                     KSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANINNVAVEGKI
                     SGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNSSRVNKVRV
                     DALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIVGSTWQNGR
                     VNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQIDAKVADYG
                     ITVTLDDTGQDLKRNLREVDYTRLNKAESERKVAYSNIEKLMPFYNKDLVVHYGNKVA
                     TTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVTFKENFINS
                     QVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGAANDAALDN
                     LYLDRKFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAFMLGLTYMN
                     RWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIIALGNSGLDNLRASNTVGLYANKL
                     ASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVREKQESPTAD
                     RKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERYRDSVDGVI
                     LSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGFNVKDETGR
                     TYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDAYGTSVYTH
                     EMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKAEKDDLNRL
                     HTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAEAILAQNNDVKKKWFRKIENYYVR
                     DTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKRNGYYTISM
                     FSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAFASGSKTFS
                     SWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITIQYELGNPN
                     STKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNAYLRTTDDF
                     RNSIYK"
     gene            complement(13041..13695)
                     /locus_tag="VUR46_001936"
                     /pseudo
     CDS             complement(13041..13695)
                     /locus_tag="VUR46_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         3947 a         3070 c         2381 g         4392 t
ORIGIN      
        1 gctgtgaatg gaccttcacc cttggcttgt tctaggtagg ctgctggaac atcaatactg
       61 tctttaacgt tgttctcaac tgcagatttg acatcgcttt ttgttacaag accgttcaaa
      121 gtaatattga cattacgtgt cttgacaacc ttagtcaaat caggtttatc tccgtctgct
      181 tcatagacag tcagggtagc ttcataggta tttgtaccat tcgtacgaag tgtatctaat
      241 agatcttgat ccttcttacc ttcagtgtta ccattcaaag atacttgata gtaatactta
      301 ccatcaggta aatttttcac tggtggaatt ttctcgtttt gagcgacacc gttatctgac
      361 catggtgcct tgtcagatgc cttgagcaag agacgagtca acataccatc gcctgcgaaa
      421 agttcgtatt taagcggttt atttacacca gccaagaacg gaccggaagc tttggcttgt
      481 tctaggtagg ctgctggaac atcgatagtg tcattaacat cctcatcgac agctttttta
      541 atatcttctg gacttgcttg tgtcccatcc acatcagccg tatctacagc tttttttaag
      601 acatctgtta gctctggatt ttcttgagtt tcttcacctt tttcaaaaag tgtatccaga
      661 cgggaagggc ttgtttcctc gctcacttca gttccttctg taggtgtaga aagtgagttc
      721 gtatttccag ccacgacctc aggtttcact tcagtcagaa cggtgtctcc ttgagtttct
      781 ggtaagtcac cctctttcgt tcccgatgtc tcttcaggta agacttgacc tggggtcgga
      841 ttgaccacat cggcacgtac agaacttggc tgaccaacta ggacaaagaa gccactaacc
      901 acaacaactg aggcaacacc gacactgaga cggcgaatag accaacgagt atatctttga
      961 tttggattga atttcatagg attctcctta gagtctttct ttatttgatg actctagtat
     1021 aatctcctga aattaaaaag gactaagaaa aagttaaaat ttttcttaaa tccctcttat
     1081 aaaacactta tattaattaa atccataaac agatttggtg atttgataga cgacattgga
     1141 cagtttgcga tctggcaaga cagaatgttt ggtcaaacgg ctcaacatgg tcttgcgaat
     1201 ggcctgaaag acttctggat tttcctgctg aatataggtc cacaattggc gcttttttgc
     1261 cagatgctcc gctgttccag atcggttgag cagggtactg gaaatcaccg tcgtgatttc
     1321 aatatgattc agcagatatt ctcgcatttt gggatgactc acttgggaca aatcaagctg
     1381 gtctaccaag agtcgattga ccttgagttg ctggtcaatg cacttaatca tcacttgctc
     1441 attgacagac tggtcctcac gcccaatcaa ataacgatag aaatcgacag gcagatagta
     1501 catggtcttg acctgctgaa ggggcgtaaa gacaaagaga ttatcgacat aaaaagcatg
     1561 ttcaggcaat tagaactggc tagcacgcaa caaatctgtc cgataaatca gcgagtgcat
     1621 catgatatac tggcctttag agaaatttcc gacctggtcc cagccaaaaa tctgccgaac
     1681 aggcaagact gaatcgtaac tcatactctt cttacgagac tgaccttcct tttcatagac
     1741 aaaattggtc acaaagacat ccacctcttg acccttgctc tcaagttcct gcaaggtttt
     1801 aagaattttc aagtaggcac gaggatccac ccagtcatca ctgtcaacta ctttaaaata
     1861 gcgcccagaa gcctctgcca agccacgatt gaccgcaccg ccatggcctt tattttcctg
     1921 atagatggct ctaacgatgt taggatactt gctagctaaa cactcagcga tttcctgagt
     1981 ctgatcctga gacccgtcat tgataatcaa aatctcaact tgctcaccac caatcactaa
     2041 cgactccaca cagtaatgaa gataggctgc tgcattatag ctagaaatgg cgatagacaa
     2101 taacttccta atctgctcct ttagggactg attttttctt atactcttcg aaaatctctt
     2161 caaaccgcgt caacgtcgcc ttgccgtata gatgttactg acttcgtcag ttctatctgc
     2221 aacctcaaaa cagtgttttg agcagcccgt agctagtttc ctagtttgat ctttgatttt
     2281 cattgagtat tactctctct tgtcacttct ttctatttta ccataaagtc cagcctttga
     2341 agaactttta ctagaagaca aggggcttct gtctctattt gccatcttgg gcatcaaaaa
     2401 agaggggtca tccctcttta cgaattcaat gctactaggg tatccaaata ctggttgttg
     2461 atgactgcca aaatataggt atctgctttc aagaggtcat ctggtccaaa ttcaacatcc
     2521 aatggggaat tttcctgctc tcggaaaccc aaaatattca gattgtattt gccacggagg
     2581 tctaatttac tcagactttg acctgcccaa gactgaggaa ttttcatctc cacgatagac
     2641 acatttttat ccaactgaaa gacatcaaca ctattatgga aaagaatggt ctgtgctaga
     2701 gactgcccca tttcatactc tggcgagata accgagtcag ctccaatctt ttctagcact
     2761 ttcttagcgg tctgactttt gaccttagca ataacagtcg gtacccccaa actcttacag
     2821 tgcataaccg caagcacact cgactccaga ttttcacctg tcgcgactac aacggtatcg
     2881 caggtatcaa tccctgctga tctcaataat tcttcatctg tgatgtcacc aatcactcca
     2941 cgcgccaaaa ctggctcaaa ctgattgatg cgctctgcgt ggtcatcaat agcgataata
     3001 ttcatattct gcttggctag ggcagctagg acactgctcc caaaaattcc caagcccaaa
     3061 attccaatcg tacgatctga catgctcttt cctttcttaa ccaatactaa tatctgcttt
     3121 catatagtga atcatatctt tcttttctgg atggtaatct gccaagctaa caaacaaggt
     3181 caagggacca attcgtccca taaacataag tggcatgata acactgagag ccaatttccc
     3241 aaggtcagga gtcagatttg ccgttacacc aactgtacta agagctgaaa tggtttcaaa
     3301 tatgaggtgg ataaagggag gattgccttt ggctgttatc cctagcagaa tcaatcctat
     3361 caagaagctc atcaaaaaga taataaagac actaaaggat ttttgaaccg ttcgcggcgc
     3421 aatcgttcgt ctcgcaacat tggcatgagg caagcctaga agctcacttc gtgcaaagac
     3481 caagaggaca aaatatgtcg taatcttgag tcccccagct gttcctccag gtgccccacc
     3541 tagaaacatc tgtaagatat aaatcaaaag agtcacagga tgagcctgag tataatctat
     3601 cgtagaaaag ccagctgttc gcatcgtcac tgtttgaaaa aagctaacta aaaccttatc
     3661 ggcaacaggg agattgccaa tcgttccagc attgttccac tcaagaaaga gagtagttgc
     3721 cgttccaaat aacaacaaac ctatagtcaa taatagtaca agcttcgtat gaaagtgcag
     3781 acgtcctttt ttctttcttc ctacatgacc agccaaatca aaccagacca taaaaccaag
     3841 gccgcctgta ataatcaagc ctgcaatcac cagattgacc agtaaatcgg tctgaaaagc
     3901 aaataaactg gtgctcccta aattatcaaa accggcatta cagaaggctg agatcgctag
     3961 aaaaatggaa ctaaaaagac cacgtcccca gccaagttga ggaataaggc gaaaactaag
     4021 caaaatagct cccaagctct caaccaaaaa ggtcgtgaga aaaatagaat agacaaactt
     4081 tctcaaagat cgagtttctc cataactaaa actatcctga atagttgcac ggctacgaag
     4141 actaagcttt tgcttgctct ggatatagaa aaccccaata aaggtcatga gccctagacc
     4201 accgatctga atcaagagca aacagattat ttggccccat atattatagg tgtgagctac
     4261 tggaagggtt gagagacctg tcacacagac tgcagagaca gcagtgaaaa gatgatcaaa
     4321 ataagtcgct cgtgagcttt caacttggac aaagggcaag ctcaaaagaa gagagcctag
     4381 taaaatgacc aaggcaaaac tcaaaaaaat acgacgggct ggcgataatc gagataagcc
     4441 tagctctatt ttttccttag ataatttgaa taacatgttt ccattgtacc ataaaaagct
     4501 cgaaatgact tagataggat aaggcaaaat ccactaacac caagcctaaa aaatgccacc
     4561 tttttattga tagcttaggc aagaacaata cttgatagat gtgactatag gtcaaaaaag
     4621 caagacagga gcttttaacg ccagctactc tatatgcttt tcaggagaaa atttctcttt
     4681 ttgattataa gcaatgaaaa ccaaggcatc gattagagag ctagtcacag gttgctcaaa
     4741 acactgtttt gagattgtgg atagaactga cgaagtcagc tcaaaacact gttttgagat
     4801 tgtggataga actgacgaag tcagctcaaa acaccgtttt gaggttgcag atagaactga
     4861 cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagctcaaa
     4921 acactgtttt gaggttgcag atagaactga cgaagtcagt aacatctata cggcaaggtg
     4981 aagctgacct ggtttgaaaa gattttcgaa gagtatcatt tcatctcact ctaaatctta
     5041 ccaacataaa acgcatagta tcaaagtttt catcacctga tatgatacgt ttttctgatt
     5101 ttaaagattt ttcccaacct caacatgcct aggacaagag gaaggtgacc tcgtttaaac
     5161 atatttttga aaagtatgag ctagacattt tatgataaaa caaatccttt gccagtacaa
     5221 ctaaaggtgg tgaacacttg ctaaactcag ttctagcgcc ttattaaaag cttccgagcc
     5281 ccagtcacga ctgtcgtact ggtccaagtc cgctagagaa tctgctgtga acaacaattc
     5341 accccagaga accccacgca attgagctac tgccgcaaga gcagaacact ccatctccac
     5401 aacagcacag ccttcttcct tacgataagc caccttttca gccgtttctc ggtaaaaacc
     5461 gtctgtcgtc caggtcatga cttcttcata aggaatccct ctgtcttcca aaacttcctc
     5521 aatagcagca atagcctctg gctgcatttc catataacga gaaggtgcca catagtggta
     5581 actggctcct tcatctcgca gagcgcgaac agggactaga aaggcatttt cctctatatc
     5641 agctaggaca ccacaggtcc cagtagagat aatctgctcc acaccatagc caatcaacca
     5701 atccataaac tgggctgctg gagcggagcc aacaggagcc tgagccagac agacctcctc
     5761 acccttgtag ttgatgacat agactggata ggtcttggta gcagaaacga attcgccgac
     5821 acaatccgcc cctacttccc ttgcatagcg gtcaatctcc tcatctaaaa atgcataaac
     5881 acacttcttt ggcaactgca agtccagccc ctcgtgattg ggcatgataa ccgcctgagg
     5941 attgtcatca aactctaaaa taggaatcgc atgtttctga atcatagccc acctcctcta
     6001 attttgtact attgtatcaa aaactgacaa agtgtcaagg aggaagctga tgaactgagg
     6061 agaaaaacat cccacttacg agatgctttg aacttgctta atgaaacaga cttgctaaga
     6121 gatagagtag gtaaatgtga actgggtaaa aaatgatgaa acctacaaaa aagaaacaac
     6181 cccagctgtt cctttttact tctatttaac aggtatttcc ttaatcacgc gcgcaggatt
     6241 gccagctagg acaacgttgt cgccaaaaga tttggtaatt actgcccctg ctcctgcaac
     6301 gacattattt cccagtgtca ctccaggaaa gacaatgacg ccaccaccag tccagaaatt
     6361 atctccgatt gtgatgggct ttccgtactc gatacctgaa ttgcgttcct gtggatctag
     6421 tggatagagg ggtgtcaaaa actgacaatt aggaccaatc atagcattgt ccccgatacg
     6481 aatgggacag atatccagca tggtcaagtt ccaattagaa taaaaatttt cccctagatg
     6541 gatgttgaca ccgtagtcca ccatcaagcg agtgttgatg taaagatttt tcccggttga
     6601 ggcaaaccaa gtcttgatga tttcggctcc cttcaagggg ttctcttcct tgttaaaggc
     6661 ggcctgtttt tggcgagaag cctgagctaa ggctctcagt tctgggtctg atggacggta
     6721 aaactctcct gctatcattt tctggtattc gctagtcata ttattcttct ccttattccc
     6781 tactatcata tcaaattttc cacgtatctg actagaataa ggagcacttt ctacaattga
     6841 tgctctacct tcatcacata ccatctatct agctaaacga atacgggtca cgatgccatc
     6901 tgagtctgtg atttccaatt ggctcgatgt catccatttg attggtgcgt caacttcttg
     6961 tgctcgttgg gcaatcgtta acagttcttc tttatgtgcg acttcgatga catagtaggc
     7021 taaacctggt aggacttgtt tacgcggatc cagacctttt cctccccatt cgttgactgc
     7081 taaatgatga tggtagtccc cagctgcgat ccaactagca ctaggcacac tgaatttatc
     7141 ctcgagccct aacaccgttt gataaaactg tctggacttt cgactatcct tgacagaaag
     7201 atgaatatgc cccattctcg taccctctgc taggataaaa ggctctactc tttcccccaa
     7261 ctcatagata tcctgagccg caaggacttc agtcaccccg ataatacgtc catcttctcg
     7321 aatatcccat gtggaaactg gcttatctcg atagagttca atgccatttc cctccaagtc
     7381 ctctaagtaa agggcctcac tgtaaccgtg atctgcaccg ccaacaagag gaatctgtaa
     7441 atccgtcagg tgcttcaaga catccgccaa agcctttcgt gtcggcaaaa gaatagccag
     7501 atggtaaaga ccataatgtt cccttacttc tccaccctct tgtgcttgaa tcaagtgtac
     7561 caaggctttt cctccaagtc ccagaacgac ctctgtatcc gtttgagata ggatttctaa
     7621 accaataatc tgctgataaa aaactgtttg actgaccaaa tccttcacat ttaaaactgc
     7681 ctctgctaaa taaatgtggc tctggtattc atatgtcata aatatttcct cttttattgt
     7741 aactttaatc attacaacta ttatataact tccctcaaga aagtcaagcc agacaacttg
     7801 aagcatccca ctcagcaaaa aacaatccca gaaaaaatct tctaggattg ttttgtattt
     7861 attttactag actagcaaag ttatttctca aatcaacatt ttctgtggga ttgaaatcca
     7921 ccttgtcacc attggtcgtt gatgagttga agatgattcc tgcaatctgc attcaatcaa
     7981 atctctacat cgatccataa gaaaaaggag tcgatttgtc atctgactcc tcatccttac
     8041 aagaaacact actcaacaat gaaactctac aatcttattt atatatagaa tttctaaagt
     8101 catctgtagt gcgaagatat gcattataga ttttttgttt taataaatgc acccaacttg
     8161 ctggggtatg actcgttgca cgatctatat tagtaatatc tttcgcagcc gcttcattaa
     8221 ttaattgttg catttgtgca gccgttgtta tagttacttc ttttgtacta ttaggattac
     8281 ctaattcgta ttgaattgtt attggtttca gattatcttg tttatctata cgttgtttaa
     8341 acattgcttt tttgaaatca gcccatgatg agtactcacc attgaatact ttcttaaata
     8401 ctaaatcatc tgtcactaaa gcaacatctc ttccatgcca tgatgagaat gttttgcttc
     8461 cgctggcaaa tgcttctgct ccgtactgat tagaaacata aggtaggaat cctttgtgat
     8521 aacctttttc cgcaagtaat tcataagcta tttttctaaa cataatatct ccaggagcac
     8581 ctttcgaatt gcttagcgct gcgtatacag gagagaacat acttatagta tagtagccat
     8641 ttcgtttata ttctctatta tcatcatagc tacgtctatt tatgatgtcg ttgtcgatta
     8701 atgagtttaa cgatgttaag ttagctactt cttcatctgt taatggacgg actttatttc
     8761 ctgcatgtgt atctttatta tgtctagtat cacgaacgta ataattttct atttttctaa
     8821 accatttttt cttaacatca ttattttgag ctaatatcgc ttctgcttcc atcgcatcaa
     8881 gtgtatacat tacatcatat gatccatgca tataactttg aagcgcctca tccgaatcga
     8941 aacgttccac cggattatat gtatgcaatc tattcaaatc atctttttct gctttatata
     9001 acgtatttaa agctaaaata tgagaattta cactatctac agattgcagt aaaccaagtg
     9061 cgtataactc cgctcccaat ccttcacgtc taccatttcc ttcaaagtag attgcagaat
     9121 cagaattatg aaccatttca tgagtataaa ccgacgttcc ataagcatct aataatctat
     9181 ctaacacaaa gtgcgttaaa cttccattcg catacgctcc tgcactacta ttatactcat
     9241 accatttccc aacaggtccg aagaattctt taatagagcc gatgttttta tccgttaacc
     9301 ttgcccaata agttcttcct gtctcatctt ttacattgaa tccatcataa actatcacag
     9361 aacggaaaag tttttctttt gaagcactgt caagaagatt gtaccaaata tcataatggt
     9421 ctctatgcct tttcgctgct atatcaactc tatttcttac ataagttcgt aaagcatctc
     9481 ctgaaagaat aactccatcc acactatcac gatatctttc atacgaaccg aatgcaagtg
     9541 tagacatatt cgatgaaata tacacagatt cttcaggtaa agttagtagt ggtaataaca
     9601 tactcttatg cccccaactt ggtgctgata ttctatcgta aactcctaat gaatattttc
     9661 tatcggctgt tggtgattct tgtttttctc gtacttctgc aatatcagac ttcatttcga
     9721 ctatatatgc ctttgtattt tctttaaacc actcgttatt tgttttgttt ggtaagaaca
     9781 gttttctata cgcttctacg aagtcaaaga ctgaatcttc tccttttacc gatgcaagtt
     9841 tattcgcata taaacctaca gtatttgaag ctctcaggtt atctagtcca ctatttccta
     9901 atgcgataat agtatccaac gttgaagtct cattatttcc gttaaagtca aacttgtacg
     9961 tagataaatc ttttgtattc attttaccat aattaatatc gtaccaacgg ttcatataag
    10021 taagacctag cataaatgct tctttgttat ttttgatttt ctcacttacg tattcaacta
    10081 caccgtctcc tgtagtattg attgatttat ccatcgctaa tacttttctt aggtgttctg
    10141 ctatattagc tttaacttct tcaaattttc tatctaagta taggttatct aaggctgcat
    10201 cattcgctgc tcctagtact tttttagtag cttctgagtt aagtgttaca ttttgcaagt
    10261 cgcttagtac gttattcgtt atcgctgtat agtctgaaac aaatgcttct ggtgtgaata
    10321 tatattcttt tcctgtaaca ttgtattcga ttacttgact gtttatgaag ttttctttga
    10381 atgttacatc taggtattct actgtattat ctttgaaatg taacataact ttatttattg
    10441 aatttttctt attattaata tccgttacta cttcatcatc tttcatcggc acaacgtcta
    10501 acaattctgt agtgtaaagt ttatctgttg tcgctacttt gttaccatag tgaactacta
    10561 ggtctttatt gtagaatggc atcagttttt ctatgttgct ataagctact tttctttcag
    10621 attctgcttt atttagtctt gtataatcaa cttctcttag attacgtttt aaatcttgcc
    10681 cagtatcatc aagagttact gtgattccat aatcagcaac tttcgcgtct atttggtctt
    10741 ttgataattt tgtagcgaat ctgtctgctt ttctattatc aactgatgta cttgcatttt
    10801 tcacatctgc tgctgcgtat tgatcaccgg tgataacata accatctcca acatctacgt
    10861 tactcacaac attatttact cgaccgtttt gccacgtaga tcctactatt cctccgactc
    10921 tagaatatcc ttgaccattt cgtatttctc cagtagcaac cgaattagat atcaatgcac
    10981 cattttctaa tctacctact atccctccag ctgtttggtt attattgcgt gcattagtag
    11041 agattaaggc atctacccta actttattaa ctctcgaact atttcctgtt atattaccta
    11101 ctattcctcc agtatcattt ttattactgt cctggtgatt tgcgataagt ttccctgtaa
    11161 acgagctgtt ttctatcact gtatttgttg cgctcgctac taatcccgca acagatttcg
    11221 cacctgagat ttttccttct actgcaacat tattaatatt cgcgctattc gctgccttcg
    11281 ccagcgctgc gacattttct ttactatcag cagaaacagt tttaatatcc aaatctctaa
    11341 ctgtagcacc atttaatgta tcaaataatg gttttttcaa atcataaatg gcatacgatt
    11401 ttgttccatc agaaccgatc aagctccctg taaatgcacc tgtgagataa cttgtctgct
    11461 tatcgcctaa gctcacctca tctgcggtca tatctgaagc caatgtatag acaccagaca
    11521 gattgctttg catggctgtt accagctgtt taaaggatgt gtaaactcct ggttgctcta
    11581 ctttagattt agctacagta aatgtgtaat catctttgta accgtctgta ccttcttcga
    11641 caagttgatc aacggctacc gtcactttat acgttccatc cgtattttct gtaatagatt
    11701 ttacaggtag gtacatttct ttgaagcgat ctgatttcac ttttacaaag tatttagccg
    11761 tatcagtcgg cgcttcactt agacttaaat atctacgata acgatcattt tctttaccgt
    11821 ataattctac tgaatcaata tctttaatct ctattttctt atactctaat tggaaatctt
    11881 gagttgatgt ttcagtattt tcctcattat tttcacccaa attataagtt aggtgtgttt
    11941 taactgtata cggtgtgtag taatctaaac ctgatattac ttgctctttg gcaggatttt
    12001 ctatatccac ctctttaact agcttgtctc catggaaaac ttgcgttttt gcagaaacat
    12061 atgctgaggt agtgtctatt aagttataac ttacagttat agattttttg ttctcaactt
    12121 ttgttaagtt tgtaatttct actgtaggtt taactttcac aagtgttcct actttaacga
    12181 cttcgttgac cggagctact tcagttcgtg acacttcttt agtttctacg acattaccat
    12241 ttacgatgta gtcttcatat tgaattgtac gtgtccctgc ttgcccttgt cgttcaatct
    12301 tacgacgatt tttcagaagt gttggatcct gaatttcttc tgttgtataa ggaatattct
    12361 ggatttccgt tctatttcgt gtagtgacct ctaaagccgg aagttcttct tctactgccg
    12421 cttcgccctc atgttcgggt tcttgtgtgc cttttgtcgc tacaggatca gtgtactctg
    12481 aaagtccatc atcccctgat gcttcacctt gtaaactaac cttcccctgt ccttggctcc
    12541 attctgaatc agctgaatga actacatctg atatttttgt agagtctggt tgactatcac
    12601 ttcgagcaga gtatttccca tcgactgtcc ttgaaatccc tgcattatcc tgtttcttag
    12661 tcttgatata acccaagtaa taagtatcat ctgattcttc agccagttgt aaaagggcct
    12721 ctaccagcaa ggatttttcc tcgtctgtca attcaccctc ggtcatatac ttataatgaa
    12781 ttggactttc catattatcg gctgataccg attgaatccc ttgactcatc aaaaagaaac
    12841 tagctaaagt aactgatacc aatcccactg acaactttct catcgagaaa ctctggcgtt
    12901 tctcaccaat actttttcgg ctcatattaa cctcgctttt tctacattct ttataccaat
    12961 ctatattttg tagaataaaa gtataaacac aaaaaaatag tatagtatgg aattttctga
    13021 gtacttttca ataattatac tcatctgctt tcaaaaagca ttctagtcca tctccgatta
    13081 acgatggact ttatcacctc cttctccagt ccttgtatga catcttggag ttgattcatg
    13141 acatcttcca aagttcgaaa ggctttattc ttaaatccac gtttacgaat ctctttccac
    13201 acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaaggtaaa gccaatatta
    13261 ctaggatgtt ctggatgtgg cgtaatattt cgccaaccat ggcgcttcaa cagttgatag
    13321 aaggcatcac gtgtgtagga acaacctaac tcctttttat aagcctgaaa taaggcatca
    13381 attgtaacaa attctcctgc ctctgcagcc ttcaaatggc gagcaagaaa aactttctct
    13441 tcctcaaccg tcatatatgc atggttacga ccaccacgag tttcttgaag gagagagtcg
    13501 agtccgaact cctcatattt ttttacattt cgccaaatcg ttgtttgatt acactctaaa
    13561 agctctataa tctctttata agatttaccc catcagacga aatagaacga tttgaaggcg
    13621 tttatgatat ttagctgtac tagagtcttt taaaagtgtt ttgatggctt ggatttcttc
    13681 tttagttgat ttcatattac tattatataa tgctttttga ttttagtcta gtattactta
    13741 tcattataca ataaatcgat agaaatttct attgaaatat acttaaaaat
//
LOCUS       DAVDHZ010000055        13314 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000055 DAVDHZ010000000
VERSION     DAVDHZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.056"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            148..321
                     /locus_tag="VUR46_001937"
     CDS             148..321
                     /locus_tag="VUR46_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457297.1"
                     /translation="MQKKEQSSRQVVVGYLMDVMSVDIEEANHLVSGLEHEGLVCFES
                     NGDVTVLVLEGQS"
     gene            318..1145
                     /locus_tag="VUR46_001938"
     CDS             318..1145
                     /locus_tag="VUR46_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET5457298.1"
                     /translation="MKRITANHYQTSERYYKLPKLLFESERYKDMKLEVKVAYAVLKD
                     RLELSLSKGWIDEEGAIYLVYSNSKLMALLGCSKSKLLTIKKTLREYGLIDEVQQSSS
                     EKGRLANKIYLGELEDDTSPVLKSDGGGVKKTRGQSQKQTGQVLNSAPSETEISETKK
                     NETERNESVIEDEEEKKEVTFGKKQEESLTRKVDHVTKYDVGYIWNLVYERLRQEGLS
                     RVTSEYAMVHFEDRYRYALEHMRFVNTAEAIAEYVFNGVLSEWSKQIRLNEAKKGGW"
     gene            1305..2663
                     /gene="dcm"
                     /locus_tag="VUR46_001939"
     CDS             1305..2663
                     /gene="dcm"
                     /locus_tag="VUR46_001939"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET5457299.1"
                     /translation="MKFLDLFAGIGGFRLGLTRQGHECIGFCEIDKFARKSYKVIYDT
                     EGEIEFHDIRQVTDQDFRQLRGQVDIICGGFPCQAFSLAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLSHDKGETFATILSTLDELGYDIEWQVLNSKDFQVPQNRE
                     RVFIIGHSRRYHPRFLFPLRGENSSAHLERLGNVNPSRKGMNGEVYLATGLSPTLTQN
                     KGEEAKIAIPVLTPDRLEKRQHGRRFKDNQDPMFTLTVQDRHGVVVAGTLPTSFVQTG
                     RVYDQSGLSPTLTTMQGGDKVPKIICREEAPHLKIKEATKLGYAKATVGDSVNLAYPE
                     STKRRGRVGKGISNTLTTSDNMGVVVAALEYRKDKWYEVTGIILDGKLYRLRIRRLTP
                     RECFRLQGFPDWAYERAESVSSKSQLYKQAGNSVTVTVIEAIAREFRKIEEEEGHEII
                     TH"
     gene            2644..3072
                     /locus_tag="VUR46_001940"
     CDS             2644..3072
                     /locus_tag="VUR46_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457300.1"
                     /translation="MKLLHTKSIRDCTELEEVIHQAEVERIAETIASLPNYDCEIEVT
                     FEDDYHQEMNVPLAYESNLHRLFEFMETQDLKNGVDSYLAEENHLVFRAFGQHYMANG
                     KDDLLTTRITVKSFGEGRTPIDMSKVFTPLTQKLPKDLSV"
     gene            3082..3465
                     /locus_tag="VUR46_001941"
     CDS             3082..3465
                     /locus_tag="VUR46_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457301.1"
                     /translation="MLEIYLSRNTSRNQNLLSFYDTHGISYTPKEVNDLSREDLLSLF
                     TKSSDCFALLSPSLQRFKGHREMKLSELVTLVLRKPDQNLRLPLVICEDKVYPDMSLE
                     EARTFLPRTHKVVSFREHLFKQLTE"
     gene            3475..3708
                     /locus_tag="VUR46_001942"
     CDS             3475..3708
                     /locus_tag="VUR46_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5457302.1"
                     /translation="MNDRFWENLESIVIERGMSWADLARKMFKGQYVYPSEFKRLYQT
                     FRHYKSHHLMPQVKWVEKVVSVLEIDYEDLFRR"
     gene            3711..4292
                     /locus_tag="VUR46_001943"
     CDS             3711..4292
                     /locus_tag="VUR46_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5457303.1"
                     /translation="MRRILLAYGAIHVNVLLVSFFLVGVLNEVVLIALQVSFFALVLW
                     VWKCFKIPKRNLSLKERGLWLLVSLGVMVSTALIMSAIFSGYAVNQETLVTVQDQAPM
                     LPFILFLLNASVVEEVFYREVLWGVLSQPVVQFLLTSFLFTLAHHPSSLITWGLYGSL
                     GLVLGLVRLKADCFTSTLVHLSWNGIVFFLSLL"
     gene            4368..4856
                     /locus_tag="VUR46_001944"
     CDS             4368..4856
                     /locus_tag="VUR46_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457304.1"
                     /translation="MSSEQQERQALQYAERSTMFTVRVLLKLLEWSARQALAQDSAYK
                     IGVQKLEELLQSPYAIEWLNISKDILDKPIDVEKFKELMESENLPIAISWQGDYLYFY
                     AKDKSLLDKHLDKLLQKLVSNPEKLQGLTLDKTLDEEIAKAKEQIVMSEPSAVKAKEV
                     IL"
     gene            4856..6676
                     /locus_tag="VUR46_001945"
     CDS             4856..6676
                     /locus_tag="VUR46_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003086094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET5457305.1"
                     /translation="MASGKKAFIFGVLGLAFGYFCHRLVLLYDSLPNQPSIERFAYLL
                     GEGQNQVLNPLWKGNFTGRSVLGFCFGFVTMGLVYLYVSTGQRVYREGAEYGSARFGN
                     NRERKAFISKNPLNDTILSRNVRLTLLEKKAPQFDRNKNLVVIGGSGSGKTFRFVKPN
                     LIQLNCSNIVVDPKDHLAEKTGKLFLENGYQVKVLDLVNMTNSDGFNPFRYVETENDL
                     NRMLTVYFNNTKGNGSRSDPFWDEASMTLVRAISSYLVDFYNPPGSTKEEADSRRKRG
                     RYPAFSEIGKLIKLLSKGENQDKSVLEVMFESYAKTYGTENFTMRNWADFQNYKDKTL
                     DSVIAVTTAKFALFNIQSVIDLTKRDTLDLKTWGTQKTMVYLVIPDNDTTFRFLSALF
                     FSTVFSTLTRQADVDFRGQLPIHVRSYLDEFANCGEIPDFAEQTSTVRSRNMSLVPIL
                     QNIAQLQGLYKEKEAWKTILGNCDSLLYLGGNDEETFKFMSGLLGKQTIDVRSTSRSY
                     GQTGSGSTSHQKITRDLMTPDEVGNMKRDECLVRIAGVPVFKEKKYFPLKHKNWKYLA
                     DKETDERWWHYHIAPLKHEEESLDLSDHRVRDLSTETTLH"
     gene            6694..6936
                     /locus_tag="VUR46_001946"
     CDS             6694..6936
                     /locus_tag="VUR46_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457306.1"
                     /translation="MNQKLTGFVYGVDASSMFAQAMALLQKGMIATGAFLVVMGIINL
                     STNIKDGGPGVRNAILEIVGGVMVGAAGAFITQITI"
     gene            6956..7807
                     /locus_tag="VUR46_001947"
     CDS             6956..7807
                     /locus_tag="VUR46_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HET5457307.1"
                     /translation="MNTLPSAFVFLASEKISSDSLFEGFNVDLESTANLIKSLADYNP
                     TVWSYMSAITKGIMQPLGVAILAVVLVLEFSKMAKKIANSGGAMTFEAIAPMMVSYIM
                     VAVVITNTTVIVEAILAAASHIIEGVAGVVSHGGATYETISGLKGSGIIGKLIVGFFA
                     ILIWLVRLVSVMVVNLLITIRFIQLYLMIPFAPLTIPTFLSDDWRSVGIGYLKNIMVY
                     ALQGVLIFLIISLVPLFESAGKLAVSNGAGVMETLATTFGGLVQAILLIIALVGSQRT
                     ARSILGM"
     gene            7997..8350
                     /locus_tag="VUR46_001948"
     CDS             7997..8350
                     /locus_tag="VUR46_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET5457308.1"
                     /translation="MNTRVFKDITKVQHRAWLGFTTRQVIFVLPAIALTILILGLNLF
                     YWQFGDWIVYGLIFTFTIPLMLFGVYRPNDLPFETYLNYRWHYEMTIPNRTLTGQKGI
                     RREKNKPLNETKDFF"
     gene            8328..10658
                     /locus_tag="VUR46_001949"
     CDS             8328..10658
                     /locus_tag="VUR46_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5457309.1"
                     /translation="MKPKTSSKHKKTGKPKEKVLPTTANTLRYQGLFPNGLMQVTSDY
                     FSQSYLLGDVNYQTVGLEDKGAIMETYSDLINSLDDKTNFQLTIFNQRVNLDKFRKSV
                     LYPMHEDGYDTYREELNRIMENNLEAGENNFSAIKLISFGKSDQNPKLAYRSLSQIGE
                     YFKSGFSEIDANFTLLNGESRVNHLADMLRGENHLPFTYQDLVRSGQTTKHFIAPTSL
                     SFKHKNYIEIDDRLLQIVYVRDYGMELGDKFLRELMQSDLEVVISLHAKGSAKSEAMT
                     KLRTKKTLMESQKIGEQQKMARSGVYLEKVSQVLESNIDEADELIKTMTQTGDKLFDT
                     LFLIGVFAYNADRLKHSLDIIKQVSGSNDLIIDNLSYMQEAAFNSLLPFGKNYLEGVS
                     RSLLTSNIAVNSPWTSVDLQDKGGKFYGINQISSNIITIDRGKLNTPSGLILGTSGAG
                     KGMATKHEIISTKLKEADTDTEIIIVDPENEYSIIGQSFGGESIDIAPDSTTFLNVLD
                     LSDDNMDEDPIKVKSEFLLSWIGKLLDRKMDGREKSLIDRVTRLTYKHFETPSLVEWV
                     FVLSKQPEQEAKDLALDMELYVEGSLDIFSHHTNIKTDSHFLIYNVKKLGDELKQIAL
                     MVIFDQIWNRVVKNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRVRKYGAIPTGI
                     TQNVETLLLDANGRRIIANSEFMILLKQAKNDREELVHLLGLSKELEKYLINPEKGAG
                     LIKAGSTVVPFRNKIPHQTKLFDIMSTDPEKMRTEA"
     gene            10655..>13314
                     /locus_tag="VUR46_001950"
     CDS             10655..>13314
                     /locus_tag="VUR46_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5457310.1"
                     /translation="MTSDKQNVKVARKTFQSSLKASRIHYRREKKGLKRSLPKRRFII
                     RRAEKAETREQRQTLKQTYQEETDLATDTFTKAISYVSPRWLKVKDIRKYRLPQARHR
                     LTVARKHLAENKMAEKEQAINPKFTYQKEPNQKTPSRFHFQKEKSLDRLQAEKKVNSA
                     KRDVKQLKRAHKAKKASTKFKRGLRYVASDSLDLVAQDDDLEGIRTVKDMSIKGRRYG
                     RFIYQSGKLLVTSGQTGMRFTKTKIAHGKERYQNFKKGKGFTRQKPLKHKRRYHTFLK
                     QARKHSVSGIKGVIQAIKGSLTFFSTIVLNPMTWVVSGLLFFLLLMMSFVVGISGTSL
                     IQQDEGELTKAYTHMTWEDAENTRTNDTGITYYTKIDDVMGFMNLKYQDYALEEVMEN
                     GDKTYQVYLSQLWHDLNGGDSLKAMLELTKEPAYKLSDDDREELKELSKEGTYLALQE
                     LDNPFQGQTEDDTLTMTVRYGYEMIEDKPTLHHHIILEAKENQVIVAPMDGKVSLDGE
                     NLIITSGKGLNKSQLTLFNVHTGRVTDGQKVQAGEMIGQTKDGSGLKVTYQKVDNDSE
                     KLVYVNPAFYFPKVIQLQTTILPTIGQFGGDEFARAKVIYEYLKSQGATNQAIAAILG
                     NWSVESSINPKRAEGDYLSPPVGATDSSWDDEGWLSLNGPAIYNGRYPNILRRGLGLG
                     QWTDTADGSRRHTLLLKYAKRQNQKWYDLDLQLDFMLHGDNPYYTNWLKDFFKNSGSP
                     ASLAQLFLIYWEGNSGDKLLERQTRAAEWYYQIEKGFSQPNGGTAQSDPKALEAVRED
                     LYDNSIPGGGDGMGYAYGQCTWGVAARINQLGLKLKGRTGEKISIINTMGNGQDWVGT
                     AARLGGETGKLPKAGAIISFAGGQYGHVGFV"
BASE COUNT         3998 a         2576 c         3068 g         3672 t
ORIGIN      
        1 ataggtgctt aaaacgctga taaatcaagg atttgagcgt tctacaatct gtcattaagg
       61 aggaaatttt tgttttaata agagaatatc gctatagcga gaacatttta ataggtgttc
      121 tcgctttttt attttcagga ggaaaatatg caaaagaaag aacagtcatc acgtcaagtt
      181 gtggtgggtt atctcatgga tgtcatgagt gttgatattg aggaggccaa tcacttggtc
      241 tcaggcttgg aacatgaagg cttggtttgc tttgaatcaa atggagatgt cacagtatta
      301 gtattggagg gacaatcatg aaacgcatta ccgcaaatca ctatcaaacg tcagagcgtt
      361 actataagct cccaaaactc ttgtttgaga gtgagcgtta taaggatatg aaactagaag
      421 tcaaggtagc ctatgctgtt ttaaaagatc gtttggaatt atctttgagt aaaggctgga
      481 ttgatgaaga gggggctatt tatttggttt attccaactc aaaactgatg gctctccttg
      541 ggtgttccaa gtcaaagttg ctgacgatta agaaaacgtt aagagagtat ggcttgattg
      601 atgaagtcca acagtcttct agtgaaaaag ggcgcttggc caataagatt tatttagggg
      661 agttggaaga tgacactagc cccgtcttaa aatcagacgg gggtggtgtt aaaaaaacac
      721 gggggcagtc tcaaaaacaa acggggcagg tcttaaattc agcccctagt gagactgaaa
      781 taagtgagac taagaaaaat gagactgaaa gaaatgagtc agtcattgag gacgaggagg
      841 agaaaaaaga agtcactttt ggaaaaaaac aagaagaatc tctcactcgt aaagttgatc
      901 atgtgacaaa atacgacgta ggctatattt ggaatttggt ctatgaacgc ttgcgacaag
      961 aaggcttgtc tcgagttacg agtgaatatg cgatggttca ttttgaggat cgttatcggt
     1021 atgctttaga gcacatgcgt tttgtaaata ccgctgaagc gattgctgaa tatgtcttta
     1081 atggggttct atccgaatgg agtaagcaga tacgactaaa tgaagcgaag aaaggtggtt
     1141 ggtgaacaga tgttttggtg gatcgtatta ggaatctgga gactagggtt gatttggcta
     1201 attgttgcaa tcatcacggc accagacatg gacgattata attgaggtag gacgttacgt
     1261 aaaatgtaag gtccttttag ttttgtcaga aaggaaggag agacatgaag tttttagatt
     1321 tatttgctgg aattggaggc tttcgactgg ggttaactcg tcaaggccat gaatgtattg
     1381 gtttttgtga gattgacaag tttgcgagga aatcttacaa agtcatctat gatacggaag
     1441 gagaaataga atttcatgac attagacaag tcacagacca agactttaga caactcagag
     1501 ggcaggtgga catcatctgt gggggattcc cttgtcaagc attttcactc gcaggcagac
     1561 gattgggatt tgaggacact aggggtactc tgttctttga gattgctcga gcggccaaac
     1621 agatccaacc acgtttttta ttcctcgaaa atgtcaaggg tttactcagt cacgacaagg
     1681 gagagacgtt tgccacaatc ctctctacat tggatgagct ggggtatgat atcgaatggc
     1741 aggtgcttaa cagtaaagat ttccaagtcc cacaaaaccg agaaagggtc tttattatcg
     1801 gacattctag aagataccat cccagattct tatttcctct cagaggagaa aatagctcag
     1861 ctcatcttga aagattagga aatgtcaatc cgtccagaaa aggcatgaac ggtgaggtct
     1921 acctagcaac aggtctctcg cctactttga cgcaaaataa aggagaagaa gcaaagattg
     1981 ccattccagt cttaacccct gatagactgg agaaacgcca acatggcaga cgttttaagg
     2041 acaatcaaga ccccatgttt accctaacgg ttcaagatag acacggtgtt gttgtcgcag
     2101 gaacccttcc gacctctttt gtgcaaactg ggcgagtcta tgaccagtct ggcctatccc
     2161 ctacccttac caccatgcaa ggaggggata aagtgcctaa gattatctgc cgtgaagaag
     2221 ctccgcattt gaaaatcaag gaagcgacca aattaggcta tgctaaggca acagtgggag
     2281 attctgtcaa ccttgcttat ccagagtcaa ccaaacgcag aggacgagta ggaaagggaa
     2341 tctcaaatac cttaaccact tctgacaata tgggagtggt ggtagctgct cttgaatacc
     2401 gtaaggacaa gtggtatgaa gtgacaggaa taatcctaga tggaaaactt tatcgtttga
     2461 gaatcagacg attgacccct agagagtgtt ttagacttca ggggtttcct gactgggctt
     2521 atgaaagagc agaaagcgta tcaagtaaaa gtcagttgta caaacaagca ggcaatagtg
     2581 tgactgtcac cgtcattgaa gctattgcta gagaatttag aaagattgaa gaggaagaag
     2641 gacatgaaat tattacacac taaaagtatt agggactgta cagagctgga agaagttatt
     2701 catcaagcag aggtagaaag gattgctgag acgattgctt ctttacccaa ctatgattgt
     2761 gagattgagg tcacttttga agatgattac catcaggaga tgaatgttcc attggcttac
     2821 gagtccaact tacatcgact ctttgagttt atggaaacgc aagaccttaa aaatggcgtt
     2881 gacagttatc tagcagaaga gaaccatctc gtttttagag cttttggtca acactatatg
     2941 gcaaatggaa aagacgattt attgaccaca cggattacag taaaaagttt cggtgaaggc
     3001 aggacaccca ttgatatgag taaggtgttt actcctctta ctcaaaaatt accaaaggat
     3061 ttatcggtgt aggaggaaga aatgctagaa atctatttaa gtcgaaatac cagtcgaaat
     3121 caaaatctcc tttcttttta tgacacgcat ggtatttctt acactcctaa agaagtgaat
     3181 gacttgtcac gtgaggactt actgagcttg tttaccaaaa gcagtgattg ttttgccctc
     3241 ttatcccctt ctctacaacg gtttaaaggt catagagaga tgaaattaag tgaattagtc
     3301 acgttggttc tcaggaaacc tgatcagaat ttgcgattac ctctggtgat ttgtgaggat
     3361 aaagtgtatc ccgatatgag tttagaagaa gcgagaacct ttctaccaag aactcataag
     3421 gtggtgtctt ttcgtgagca cctctttaag caactaacag aataaggagg agctatgaac
     3481 gaccgctttt gggaaaattt ggaaagtatc gttattgaaa gaggcatgtc atgggctgat
     3541 ctcgctcgaa agatgtttaa gggtcaatac gtttatccta gtgagtttaa acgtctctac
     3601 caaacctttc gtcactacaa atctcatcac ctcatgccac aagtcaaatg ggtggagaaa
     3661 gtggtgagcg tcttagagat tgactatgaa gacttgttta ggaggtagac atgagaagga
     3721 tattgctggc gtacggagcc attcatgtta atgttctttt ggttagtttc tttttggtag
     3781 gagtgctaaa tgaggtagtg ctaatagcct tacaagtttc tttttttgct cttgtactgt
     3841 gggtctggaa atgttttaag atacctaaaa gaaatttatc cttaaaagag agagggcttt
     3901 ggttgcttgt cagtcttggt gtcatggtga gtacggctct tatcatgagt gccatctttt
     3961 caggatatgc ggtgaaccaa gaaacgttag tgacggttca agatcaagca ccaatgttgc
     4021 cttttatcct ctttctcctc aatgccagtg tggtggaaga agtattttac agagaagtgc
     4081 tgtggggagt cttgtctcaa cctgtggttc agtttctgtt aacgagtttc ctctttactt
     4141 tagcccatca cccatctagt ctcatcactt gggggcttta tggtagttta ggactggtgc
     4201 taggactagt tcgcttaaag gctgattgtt tcacctcaac cctcgttcat ttgtcttgga
     4261 atggaattgt ctttttcctg tctttgttgt gataccaaaa tcaagggtac tttcgtatca
     4321 tgaaagcacc ctagtgttta taagggaatc atgccaagga gggaatgatg tcatccgaac
     4381 aacaggaacg ccaagcgtta cagtacgcag agagaagcac tatgtttacc gttagggttc
     4441 tcctcaagct cttagagtgg tccgctagac aagctttggc acaagactcg gcctataaga
     4501 ttggggttca aaagttagaa gaactccttc aaagccctta tgccattgag tggcttaata
     4561 tctcaaaaga catcttggat aaacccattg atgtcgagaa attcaaggaa ctgatggaat
     4621 cggagaatct gcctattgcc attagttggc agggagacta cctttatttc tatgctaagg
     4681 ataaatcttt gttagataag cacttggata agttgcttca gaagttggtt tccaatcccg
     4741 aaaaactgca aggcttaact ctggataaaa ccttagatga ggaaatcgct aaagccaagg
     4801 aacagattgt gatgtcagaa ccttctgctg tgaaggccaa ggaggtaatt ctctaatggc
     4861 ctcagggaaa aaagctttta tctttggtgt tttaggactt gcctttggct atttttgcca
     4921 tcgcctagtc ttgctttacg atagtctccc aaatcaacca tcgattgaaa ggtttgccta
     4981 tctcttagga gaaggtcaga atcaggtttt aaatcccttg tggaagggca actttactgg
     5041 tagatcggtt ttagggtttt gttttggatt tgtgacgatg ggactagtct atctttacgt
     5101 ctcaactggt cagagagtct accgagaagg ggctgagtat ggctctgctc gttttggaaa
     5161 caatcgggag cgtaaagcct ttatcagtaa gaaccccttg aacgatacta tcttatctcg
     5221 aaacgttagg ctaactctct tagaaaagaa agccccacaa tttgaccgaa acaagaactt
     5281 agtggtcatt ggtggatcag gatcagggaa aacctttcgc tttgtcaaac ccaatctgat
     5341 tcagcttaac tgttccaata ttgtcgttga tcctaaggac cacttagctg aaaagacagg
     5401 gaagctcttt ttagaaaacg gctatcaggt caaggtctta gacctcgtaa acatgaccaa
     5461 ctcagatggc tttaatccct ttcgttatgt ggaaacggag aatgatttga accgtatgct
     5521 tacggtctat ttcaataata ccaaaggcaa tggcagtcgc agtgatccct tttgggatga
     5581 agcttccatg accttagtga gagccatttc ctcttactta gtggattttt acaatcctcc
     5641 tggtagtacc aaggaagaag cagacagtcg ccgtaagcgt gggcgttacc cagccttttc
     5701 agaaattgga aaactcatca agctcttatc caaaggggaa aatcaagata agagtgtctt
     5761 agaagtcatg tttgagagct atgccaagac ctatggaacg gagaacttta ccatgcgtaa
     5821 ctgggcagac ttccaaaact acaaggataa gaccctggat tcggtgattg ctgtaacaac
     5881 tgctaagttt gccctcttta atatccaatc cgtcattgac ttaaccaagc gtgatacctt
     5941 ggacttaaag acatggggga cgcagaaaac tatggtctat ctcgttattc cagataatga
     6001 caccaccttt cggtttctct cagcactttt tttctccacc gtcttttcaa ccttaaccag
     6061 acaagctgac gtggacttta ggggacaact gcctatccac gttagaagtt acttggatga
     6121 gtttgcgaat tgtggtgaaa tcccagactt tgcggaacaa acctcaacgg ttcgctccag
     6181 aaacatgagt ctcgttccta tccttcaaaa cattgcccaa cttcaaggac tttataagga
     6241 gaaggaggct tggaaaacga ttctagggaa ctgtgatagt ttgctttatc ttggtggcaa
     6301 tgatgaagag accttcaagt tcatgagtgg tctcttaggc aaacaaacca ttgatgtaag
     6361 aagtaccagt cggtcgtatg ggcaaacagg gtctggttct acctcccatc aaaaaattac
     6421 gagggatctc atgacccctg atgaagtcgg aaacatgaaa cgagatgagt gcttggtgag
     6481 aattgcaggg gttcctgttt ttaaggagaa gaaatatttc cctttgaaac acaagaactg
     6541 gaaatatctc gcagataagg agacagatga gcgttggtgg cattaccaca ttgccccctt
     6601 gaaacatgag gaggaaagtt tggacttatc agaccacagg gttagggatt taagcacaga
     6661 aaccacacta cactaataga aatgaggaat cgtatgaacc aaaaattaac aggctttgtt
     6721 tatggcgtgg atgcaagttc catgtttgcc caagccatgg cacttttaca aaagggaatg
     6781 attgcgacag gagcctttct tgtcgtgatg ggcattatta acctttcaac caatatcaaa
     6841 gatggtggac ctggtgttcg caatgccatc ttagaaattg tgggtggtgt catggtgggt
     6901 gccgctggtg cctttatcac tcaaattacc atttaggagg gctaggtatg acaagatgaa
     6961 tacattacct tcagcttttg tctttctagc ctcagagaaa atttcaagtg atagcctctt
     7021 tgaaggcttt aacgtagact tggaatcgac cgctaacttg atcaaatccc ttgcggatta
     7081 taacccaacc gtatggtctt atatgtcggc catcacaaag ggaatcatgc agcccttggg
     7141 agtggctatt ttagctgttg ttctagtcct tgagttttct aaaatggcta agaaaatcgc
     7201 caactcaggt ggagccatga ccttcgaagc cattgcccca atgatggtct cttatatcat
     7261 ggtggctgtg gtcattacaa atactactgt gattgttgaa gccatcttag ccgctgcttc
     7321 tcacatcatt gaaggagtgg ctggcgtcgt ttctcatggg ggagcgactt atgagaccat
     7381 ttcagggtta aaagggtcag gaattattgg aaaattgatt gtcggcttct ttgccatttt
     7441 gatatggctg gttcggttgg ttagtgtcat ggtagtgaat cttctcatta ccattcgctt
     7501 tatccaactt tatctcatga ttccttttgc gcctctaacc attccaacct tccttagtga
     7561 tgactggcga agtgttggga ttggctacct gaaaaacatc atggtctatg ccctccaagg
     7621 agtcttaatt ttcttaatca tctcccttgt gcccctcttt gaatctgctg ggaaattagc
     7681 tgtttcaaat ggagcaggag taatggagac gttagcgact acctttggtg gcttagtcca
     7741 ggctatttta ttaatcattg ccttggtggg cagtcaacgg actgcaagaa gcatcctagg
     7801 catgtgagag taggacagga atcggtactg ctttgcagtc gaaggcgtcg tcttacctcc
     7861 gcaaggacga ctagaactgt catagctagg aactagcgta gagagttcag acgtctactg
     7921 cgtcaaagac atgaaaccgt tcaaactgga ctgagatttc catcttagtc ctttttcaaa
     7981 gaaggagcta ctatttatga atacacgtgt ttttaaggac atcacgaaag tccaacatag
     8041 ggcttggttg ggctttacca cacgacaagt catctttgtc ttgccagcta ttgccctcac
     8101 aatccttatc ttaggactga acctttttta ttggcaattt ggggattgga ttgtctatgg
     8161 acttattttt acttttacca ttcctctcat gttatttggg gtctatcgtc ctaatgactt
     8221 gccctttgaa acttatctta attatcgatg gcattacgaa atgactatac caaaccgcac
     8281 actaactgga cagaaaggaa tacgccgtga gaaaaacaaa ccactcaatg aaaccaaaga
     8341 cttcttctaa gcataagaag acaggtaaac caaaagaaaa ggtcttgcca acaactgcca
     8401 atacccttcg ttaccaagga ctttttccta atggtctcat gcaagtcaca tctgattatt
     8461 tttcccagtc ctatctttta ggagatgtta attaccagac ggtaggactt gaagataagg
     8521 gagcgattat ggaaacttat tcggacttga ttaacagttt ggatgacaag accaatttcc
     8581 aattaaccat ttttaaccaa agagttaact tggacaagtt tagaaagagt gtcttgtatc
     8641 ccatgcatga ggatggctac gatacttacc gtgaagaact caatcgtatc atggagaata
     8701 acctagaagc tggtgaaaat aacttttcag ctattaagct tatttcgttt gggaagtcag
     8761 accaaaatcc gaaactggct tatcgctctc tttctcaaat tggggaatac ttcaagagtg
     8821 gtttttcaga aatagatgcg aactttactc tcctcaatgg agaaagccgt gtgaatcact
     8881 tggctgatat gttgcgaggg gaaaatcatc tgccctttac ctatcaagac ctggtgcgtt
     8941 cgggacaaac gaccaagcat tttattgccc caaccagtct atcctttaaa cataagaatt
     9001 atatagagat tgacgataga ctccttcaga ttgtttacgt tcgtgattat gggatggaat
     9061 tgggggacaa gttcctacgt gaactcatgc agtctgattt ggaagtggtc attagtttac
     9121 atgccaaagg ctcagccaag tcagaagcta tgaccaagct ccgcaccaag aagaccttga
     9181 tggaatcaca aaaaattggg gaacaacaaa agatggcacg atcaggtgtc tatcttgaaa
     9241 aggttagtca ggtcctagaa agcaatatcg atgaagctga tgagctgatt aaaaccatga
     9301 cgcaaacagg agacaagctc tttgacaccc tctttttgat tggggtcttt gcgtataacg
     9361 cagatcggtt gaagcactca cttgacatta tcaagcaagt gtcaggttct aatgatctca
     9421 ttattgataa tctttcctac atgcaagaag ctgcctttaa tagcttgtta ccttttggaa
     9481 agaactatct tgaaggtgtg tctcggtcac tcttgacttc aaacattgcc gtcaattccc
     9541 catggacttc cgttgattta caagataagg gtgggaaatt ctatgggata aatcagattt
     9601 caagtaatat tatcaccatt gaccgtggga aactcaatac cccatcaggt cttattttag
     9661 gaacatcagg tgctggtaag ggaatggcaa ccaagcatga aatcatctca accaagttaa
     9721 aagaagcaga tactgatacc gaaatcatca ttgtcgaccc tgaaaatgag tatagtatta
     9781 tcggccaatc ctttggtggg gaaagcattg acatcgcgcc tgactctact acctttttaa
     9841 acgtcttaga cctatctgat gataacatgg atgaagaccc tatcaaggtc aagtcggaat
     9901 ttcttctctc ttggattgga aaactcttag accggaaaat ggatggtcgc gagaagtcac
     9961 tgattgatcg tgtgacacgg ctcacctata agcattttga gacaccgtcc ttagtagaat
    10021 gggtctttgt cctctccaaa caacctgaac aagaagccaa ggatttggct cttgatatgg
    10081 aactctatgt ggaaggctca cttgacattt tctcacacca caccaacatc aaaaccgata
    10141 gtcattttct catttacaat gttaaaaagt taggggatga attgaagcag attgccctca
    10201 tggtcatctt tgaccagatt tggaatcgtg tggttaaaaa tcaaaaacta gggaagaaga
    10261 cttggattta ctttgatgaa atgcagcttc tgttgctgga taagtacgct tctgatttct
    10321 tcttcaagct ctggagccgt gtccgtaagt atggggcaat tccaacaggg attacgcaga
    10381 acgtggaaac tcttttgtta gatgccaatg gcagacgcat tatcgctaat agcgaattca
    10441 tgattctctt aaaacaagct aagaatgacc gagaagagtt ggttcatctt ttgggcttat
    10501 ccaaagagtt ggagaaatat ttgatcaatc ctgaaaaggg agctggattg attaaggcag
    10561 ggtcaacggt tgttcctttt agaaataaaa tcccacatca aaccaaactc tttgacatca
    10621 tgagcaccga tccagaaaag atgaggactg aagcatgaca tcggacaaac agaacgttaa
    10681 ggtagcccgt aaaacctttc agagtagttt aaaggctagc cgtattcatt accgtaggga
    10741 gaagaagggg ctgaaacgct cacttcctaa acgacggttt atcatcagac gggcagaaaa
    10801 agctgaaacg agagaacaaa ggcaaacctt gaaacagacc taccaagagg agacagacct
    10861 agcgacagat acctttacaa aagctatctc ctatgtgtca cccagatggc taaaggtcaa
    10921 ggacatcaga aagtatcgcc ttcctcaagc cagacatcgc ttaacagtag cgagaaaaca
    10981 cttggcagag aacaagatgg cagaaaaaga gcaggctatc aatcctaagt tcacttatca
    11041 gaaagagcca aaccaaaaga ctccttcacg atttcacttc cagaaagaga aaagtcttga
    11101 ccgccttcag gcggaaaaaa aggtaaactc agcgaagcgt gacgtgaagc aactgaaaag
    11161 agcccataag gctaagaaag cctctacgaa attcaaacga gggttacgct atgtcgcttc
    11221 agactcactt gatttagttg ctcaagatga tgacctagaa ggaattcgaa ccgtaaagga
    11281 tatgagtatc aaaggcagac gctatgggag gttcatctat cagtcaggaa aattgcttgt
    11341 gacaagtgga cagactggta tgcgttttac caagactaaa atcgcccatg gcaaggaacg
    11401 gtatcagaat ttcaaaaagg ggaaaggctt cacccgtcag aaacccttaa aacacaaaag
    11461 acgataccac acttttctca aacaagctag gaaacacagt gtgtcaggaa taaaaggggt
    11521 tattcaagcc atcaagggaa gtctaacctt cttttcaaca attgtcctca atcccatgac
    11581 ttgggtcgtg tcaggtctct tatttttctt gcttttgatg atgagttttg tcgttggaat
    11641 ttcaggcacc agccttatcc aacaagatga gggtgagctg acaaaagcct atacgcacat
    11701 gacgtgggaa gatgcggaaa acaccagaac caacgatact ggcattacct actacacgaa
    11761 aattgatgac gtcatgggct ttatgaacct caagtatcaa gattatgctt tagaagaagt
    11821 tatggaaaat ggggataaga cctatcaagt ttatttgagt cagctttggc atgacttaaa
    11881 cggtggggat tctttaaaag ctatgcttga gctaaccaag gagcctgcct acaaactctc
    11941 ggatgacgat agggaagaat tgaaggaact aagtaaggaa ggtacctacc ttgccctaca
    12001 agaattggac aatccttttc aaggacaaac tgaagatgat acgctaacta tgacggttcg
    12061 ctatggctat gagatgattg aggacaagcc aacgcttcat caccatatca ttttagaagc
    12121 caaagagaac caagtgattg tggcacccat ggatggcaag gtatcgcttg atggagagaa
    12181 ccttattatc acgtcaggta agggtctcaa taagtctcaa ctgaccttgt ttaatgtcca
    12241 tacaggtcga gtgaccgatg gccaaaaggt tcaagcagga gagatgattg gtcaaaccaa
    12301 agatggttct ggtctcaaag taacctatca aaaggttgac aatgattcag agaaactggt
    12361 ttatgtcaat ccagcctttt attttccaaa ggtgattcaa ctccaaacga ccattctacc
    12421 gactattggt caatttgggg gcgatgagtt tgcgagagct aaggtcatct atgagtattt
    12481 gaaaagccaa ggtgcgacca atcaagcgat tgcggctatt ttagggaact ggtcagtaga
    12541 atcctctatc aatcctaaac gagcagaagg tgactactta tcgcctcctg tgggggcaac
    12601 ggatagctct tgggacgatg agggatggtt gtcccttaat ggtccagcta tctataatgg
    12661 caggtaccca aatatcctaa gacgtggctt aggattaggt cagtggacag atacggcaga
    12721 tgggtcacgc agacatacgc tcttattaaa atatgccaaa cgacaaaatc agaaatggta
    12781 tgacttagac ttacaactgg atttcatgtt gcacggagat aatccttatt acaccaactg
    12841 gttaaaagac ttcttcaaaa attcaggaag tccagctagt cttgcccaac tctttctcat
    12901 ttattgggag ggaaatagtg gcgataagct cctagaacgt caaacaagag ccgccgagtg
    12961 gtattaccaa attgagaaag gctttagcca acctaatggt ggaaccgccc aaagtgatcc
    13021 aaaagcactt gaagctgttc gagaagacct ttatgataat tctatcccag gtggtggtga
    13081 tggcatgggc tatgcctatg gtcaatgtac ttggggagtg gcagctcgga tcaaccaact
    13141 aggcttgaaa ctcaaaggca gaactggtga gaaaatctca atcatcaata ccatgggaaa
    13201 tggtcaagat tgggtaggca ctgcggcacg tcttggtgga gagacaggaa agttacctaa
    13261 agcaggagcg attatctctt ttgcgggtgg tcagtacggg catgttgggt ttgt
//
LOCUS       DAVDHZ010000056        12894 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000056 DAVDHZ010000000
VERSION     DAVDHZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.057"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..2669)
                     /locus_tag="VUR46_001951"
     CDS             complement(<1..2669)
                     /locus_tag="VUR46_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5457311.1"
                     /translation="MDQEKGRPKTIGHRLDRKLEKVRKNYRTVQQDSAKQLTKLQSQT
                     HSKRQLVKKSRSQFRASKNKVKKIQKEYKRIQKEYKNIQKQGRNLGKEGKSLRPEEIK
                     KQVFLKQELDRNNKKRVFLKQELDKAKLEKKTSKRTFKVAQEANGGSRKKKFLRAAKQ
                     SVERVANQQASSVAHQDDTLSDIARTKYRYQDIQIQGKRIKTIGKYSGKLGQGMVKSS
                     YSLGNRVYNKAKGRGFTQTPREFSWEGKLSRRIQDYKKRLATSKTGKVAKKARKFYRV
                     GSKPLKVIIKNPFSLKAYLIAFGLLLFLAILGIGSSGITRQDEFDMNDTWLYLSKLDR
                     EKSNDKVDYWTKIDDPLLYLNYKYDDISDKLRIDGNNYFSQQNRGKLYLDTLWKNLNG
                     DKDNLKTMEELYTKNNLYKLDKDELEEYKELLEIARDSGKYMLLQELDNPFYTEEQPE
                     SQAPLQIIERFGYKSKTEVFNGSVLQVSGGQSLLAVLDGKVEVKGSDIEISDQDSKFL
                     YKNVDTIRYKTGDHVKAGDIIGKVAPEGNQTVYYQKLEPDRLNKKDKDGNVEKSWTYV
                     NVGFYFQRVEYTQATSVVSNIETSGEKGRRARAFADAIKKNIPEATDEGIAAVLGGFD
                     IESSITFKRYETDYLTNNQFDKVAKEPTAENLVGNWGAFQAMYPTLPLNERGYLVNGL
                     HYIGIGIGQFTGPRALALWNFAKSVNGDIWSAEVQTKFLLEEDDPTRRAAFRRIVTST
                     GSVEALAEDFLNAWLGVPGNKLLERQNAARQWLNFLKNKGGGSTGVSSKQVPAEYKDK
                     LPYGLPTDQALLEGQGYSGNAYELGNCTWYVYNRFAQIGVGIHPYLGNANQWVDSGQA
                     QGYDISTTPKPGSAAVFMNGVAGASPIYGHVAF"
     gene            complement(2680..5043)
                     /locus_tag="VUR46_001952"
     CDS             complement(2680..5043)
                     /locus_tag="VUR46_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HET5457312.1"
                     /translation="MSLFKSKREKLEKAEKKKIDRLRRQMKPTTQNTINYTLLHEDGL
                     MHIAREKYSRSFMLGDASYSTAQQDEKESIIDTTMDALNSLDEGSNYQLLVINRRVSD
                     NSLQNILYEETNDGFDDYREELNEMIKERFTTHANNFEVHKYVTISTNADDRKQAQLI
                     LQDIGVSLGTQFQESDITFRDMNGLDRLKVFSELLRDNPYVNFDYKEIALTGLFTKSF
                     IAPNRIEFQEKRMIIDDRWCKVLYARRYPNWMSDRLIRDLTTLGLELAITIHAEPYEN
                     VEILEKIDDAETDAEIGKLRSKRKAAQSGIFDDAVVAGRDQEISEATKKWRDEITEYD
                     QKIFSGLIAVYFKADNQEELQRNEQKIKRAGRKLGVEFEDLYYYQEEALNTVLPIGEC
                     FLNVKKNFMRKMTTANIATQVPFTNVDLKSESSLARYYGQNQLSNNIITLDRKRDLNT
                     GSGVVLGSSGSGKSTTIKGGEVIPTLLKYPEDRVIIVDPEDEYSDIGRAFGAQMVDIS
                     IGSKTHINLLDLPDLDRLDDEDDDPIGDKANLLMGLFESILSEVTDAQIGIIDRVTGV
                     TYERYLTENFTPTLKEWHQVLKEQPEPEAQDLALAVETYTTGSQDIFAHNTNVDLNHR
                     FVIFNLKKLSHKLKPFALMVIQDYIWNQIVENQGKCTTWVYFDEMQILFKNKAQADFF
                     TTLYSRIRKYGAIPTGITQNVETLAAVEEGRKLLSNSEFMILLKQKPQDLAILKEIVN
                     LTDKQIRYLARPKAKGTGLIVAGPVVVPFENPIPKNTKLYNLVATDA"
     gene            complement(4985..5359)
                     /locus_tag="VUR46_001953"
     CDS             complement(4985..5359)
                     /locus_tag="VUR46_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457313.1"
                     /translation="MKKIGSEFLREFETEDKPILFGLTSRMLVLYLCLIIAVSGTTAS
                     YFFGLPDWYIYLWDALFVVPGGMYGTGMTKRMRIKEKINFFFRIQQRTYEIEFGKVGM
                     YTKDEFIQKQKRKTRKSRKEKN"
     gene            complement(5458..5961)
                     /locus_tag="VUR46_001954"
     CDS             complement(5458..5961)
                     /locus_tag="VUR46_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457314.1"
                     /translation="METLKEIGNKQFNDLQKKHGTRELKDKITSLEQEITRLSWFAYE
                     HELLSEPLLEWILDGKVKISEIPRAVRMSSYGDELYIYAWRYAEAKQDAFYGMRILTL
                     LQEDITYCAIADSISQTEYVYRLEQWIKYMDRGKMVFKGDENFERYFQEQKTANRSLF
                     DTEGVGI"
     gene            complement(6049..6798)
                     /locus_tag="VUR46_001955"
     CDS             complement(6049..6798)
                     /locus_tag="VUR46_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET5457315.1"
                     /translation="MNLDIRELTSSLSSYGSATNQAVNMMADAVRPIGYILLGLFFWF
                     EMASWSQMVKSRGGSLTQKIWLEALMKYLFAFIMISASSQICDAILELLNIIVKVIAH
                     VTPTVKATIDSNISGGKGIVEKTIITFVGKAVSGVANVILGIIVFLRYLDLYMLKALA
                     PLLVAFFMMDSLRSVTINFLKYFAASALIGVILIIVSVVYDSIVAADILKVTTGSSDS
                     WGTAFASIAKGVIYIFVMVGSSRKAKQLLGV"
     gene            complement(6808..7035)
                     /locus_tag="VUR46_001956"
     CDS             complement(6808..7035)
                     /locus_tag="VUR46_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457316.1"
                     /translation="MEIITKIITGLGVVGTITGLIWIWNGAVDYIQGRKNKDKQRQDD
                     GSDSMINGAFLAVASAGIAAAVVAALSQLKF"
     gene            complement(7118..7537)
                     /locus_tag="VUR46_001957"
     CDS             complement(7118..7537)
                     /locus_tag="VUR46_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457317.1"
                     /translation="MKFGSDFSWLWVAIIRIFTAPFYIVLWCINVVKSTIGMFILWVI
                     AKICITIVLIGGMAIIHHLFNFPSENIIDNIFGWYTPHILGMSHDSLITAGQVVDAPK
                     GGGLFFPYPNFEVPIIIGLSILVATVRTIYREEFEEL"
     gene            complement(7609..12054)
                     /locus_tag="VUR46_001958"
     CDS             complement(7609..12054)
                     /locus_tag="VUR46_001958"
                     /inference="COORDINATES: protein motif:HMM:TIGR04228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5457318.1"
                     /translation="MNRINQKNASIRAENEKNQRENQAEIDRINQENAEIRKRNEAKR
                     GAYESSLTDYTKKLATIKAERDAIQTSKPLFGSETGFKVYGGYNSAGRGSLDYYNDFT
                     VVPDDNLPVESMRGFLGYHADTYVTGGAGTRVSKDSTETYDIIKSPTFGDTFYIHNIG
                     TLTDGRKIMAKVMVSDLGDYQGEVRNGVPVTDSDIYLKGGDGGSFYFVYNNHTRLEMV
                     FDFYIEGTTTPVSLLIGTVITDVDWGQGSNLSYGSSGRGMVLNPSGSGLDFDGRVMKG
                     VENGVNDTSDIPKASFASVGYGSSLTYLHTSSPGSTEGRTPAEWDAENLSGNVQNVVF
                     TILGEGAELKSIPPVNPPRKPTYEVETTPPNSPTGKPEEVLPPKPEEIKEKEIPSLVS
                     PPTVRVRYARLQAMPDLEKFVKNSSGESIDKSYVPKLSTVQWELTTKPLPANREAITD
                     FEIVDALPSGFVLDVEASKKISSDFELTYDESSHVVRMKGLESLKSKLNQDLSKEVQV
                     PAPILVGKVTNDGATYKNNFQLKINNKYASYSNIVQISTPGKPNDPDNPNNNFIQPLK
                     HNYNKDKVIIDGKPVLVGSTNYYHITLDYDQYKGMKADSSTILKGFGAIDDYPEEAVT
                     INQSDIRYIDSEGKEVAGISVYQYDSIDAVDNDKVKAFLASSEIKPKGAFQVFLVDDP
                     EAYFNQYIKSGKSVTIIDPMVTKEELRNTGKSFENTAYQVDFGNGYQTDTVVNNVPTV
                     KPTKKNLNKAGVNIDGKQVLAGSVNYYKVTADYSQYKGIEADKDRIGKGFYIVDDYPE
                     EAVTINQDGVQVTDSKGQVVKGLKMALYDSLDKAPSGVQESLESSHFTPKGAIQVFEA
                     ENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQLDFGSGYQTDKVENNV
                     PTAKPTKKNLNKAGVNIDGKQVLAGSVNYYKVTADYSQYKGIEADKDRIGKGFYIVDD
                     YPEEAVTINQDGVQVTDSKGQVVKGLKMALYDSLDKAPSGVQEALKSSHFTPKGAIQV
                     FEAENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQLDFGSAYITDTVV
                     NNVPTVKPTKKNLNKAGVNIDGKQVLADSVNYYKVTADYSQYKGIEADKDRIGKGFYI
                     VDDYPEEAVTINQDGVQVTDSKGQVVKDLKMSLYESLAKAPSGVQEALKSSHFTPKGA
                     IQVFEAENPEEFYKTYVQAGEVLTITNPMTVKKELGQTGGKYENTAYQIDFGMDYVTE
                     TVVNNVPKIEPKKDVVIDHLSKESLDGKEVKLNQTFNYKLVGSLVPKDRSEQLFEYKF
                     SDDYDETHDDYQSVYKVFAAVDFETSDGQKFKAGDELTKFTSQVVDKAKGKVDISFDD
                     ALLKSILETSEFQAEVYLQMTRIQSGAVENTYYHTVNGVEVASNTVVTQTPEEPKTPE
                     EHPQQPERSLPSTGEQASAELLLAGLAMGGAASGLLYSKRKKKEA"
     gene            complement(12072..12578)
                     /locus_tag="VUR46_001959"
     CDS             complement(12072..12578)
                     /locus_tag="VUR46_001959"
                     /inference="COORDINATES: protein motif:HMM:NF037874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457319.1"
                     /translation="MHKARETKTYGSIRKSKIYGTCGVILGLAALSMISPVIADERTE
                     NKATNAPYAQTSPSSISTENQGKSEEKTGTLEVSISHSSLDETIRKAQEAGLKVEFDS
                     VVDKGTASTASELEKSKRKSRVIIAHKQIVLRKLLKNIVKIKDKIKRTERKSKMKILR
                     RRNNIKRI"
     gene            complement(12724..>12894)
                     /locus_tag="VUR46_001960"
     CDS             complement(12724..>12894)
                     /locus_tag="VUR46_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface protein"
                     /protein_id="HET5457320.1"
                     /translation="DSSYKAWYYLKSDGSYLRDQWFKDGSAWYYLKADGKMAQNETIG
                     AYYLDYSGKWIS"
BASE COUNT         3650 a         2891 c         2072 g         4281 t
ORIGIN      
        1 cagaaagcaa cgtgaccata gattggcgat gccccagcta caccattcat gaatacagct
       61 gcagaacctg gtttaggagt cgttgaaatg tcatatcctt gcgcttggcc actatcaacc
      121 cactgattgg catttcctag atagggatga ataccaactc caatttgagc aaagcgatta
      181 tagacatacc aagtacaatt ccctagttca taagcgttac ctgaatagcc ttgtccttct
      241 aaaagtgctt gatcggtagg tagtccataa ggtagcttat ctttatattc tgctggaact
      301 tgcttgctag aaacacctgt cgaacctcct cctttatttt ttaagaaatt caaccattga
      361 cgagctgcat tttgtcgttc taagagctta ttacctggta ctcccaacca agcgttcaag
      421 aagtcctctg caagagcttc tacggaaccc gtcgatgtca caattcttct gaatgctgca
      481 cgtctagttg gatcatcttc ctccagaaga aattttgttt ggacttctgc agaccaaata
      541 tctccattca ctgattttgc aaaattccac aatgcaagag cacgagggcc agtaaattga
      601 ccaatcccaa tcccgatata gtgcaaacca ttgactagat accctctttc atttagaggc
      661 aaagtagggt acatagcttg aaaggctccc cagttgccaa ctaaattttc tgcagttggt
      721 tctttagcaa ctttatcaaa ctgattatta gttagatagt ctgtttcata gcgtttaaaa
      781 gtgatggaac tctcaatatc aaatcctccc aaaacggctg caatcccttc atcagttgcc
      841 tccggtatat tctttttaat cgcatccgca aaagctcttg cacgtcttcc tttctctcca
      901 gatgtttcaa tattactgac aacagacgtt gcttgagtgt actctacacg ctggaagtaa
      961 aaaccgacat tgacataagt ccaactcttt tcaacattac catctttgtc tttcttattt
     1021 aatcgatcag gttctagctt ttgataataa acggtttgat ttccttcagg tgctaccttt
     1081 ccaataatat ctccagcttt gacgtgatca cctgttttat agcgaatcgt atctacgttc
     1141 ttatacagaa acttggaatc ctgatcacta atttctatgt cactcccctt aacttcaact
     1201 ttcccatcta aaacagctaa cagagactga cctcctgaaa cctgcaaaac agatccatta
     1261 aaaacttccg tcttcgattt atatccaaaa cgctcaataa tctgaagagg tgcctgcgat
     1321 tcaggttgtt cttctgtata aaatggatta tctagttctt gaagcaacat atattttcca
     1381 ctatctctag caatttctaa gagctcttta tactcctcta actcgtcctt atcaagctta
     1441 tagagattat ttttggtata aagctcttcc atcgttttaa gattgtcttt atccccattc
     1501 aaattcttcc ataaggtatc taagtaaagt tttccacgat tctgttgtga aaaatagtta
     1561 ttcccgtcta tacgaagctt atctgaaata tcatcatact tataattcaa gtataaaagc
     1621 ggatcgtcaa tttttgtcca ataatctacc ttgtcattcg atttttcacg atccaatttt
     1681 gaaagataca accaggtatc attcatatca aattcatctt gacgggtaat tcctgaacta
     1741 ccgataccaa gtatagccag aaacaaaagc agaccaaatg caatcagata agcctttaag
     1801 ctaaatggat ttttgataat aactttaagc ggtttagaac ctacacggta aaacttccta
     1861 gccttcttag ccactttccc tgttttagaa gtagccaagc gtttcttata atcctgaata
     1921 cgacgagaga gttttccttc ccaagaaaat tctcttggag tttgagtgaa gcccctaccc
     1981 ttagccttat tgtagactct atttccaagg ctatagctcg atttaaccat tccttggcca
     2041 agtttaccgc tatacttccc aatcgttttg attcgtttcc cttgaatctg aatatcctga
     2101 taccgatatt tagttcgtgc tatatctgat agtgtatcat cctgatgcgc aacagagcta
     2161 gcctgttgat tagcaactcg ttctacagat tgttttgccg cacgaagaaa cttcttcttg
     2221 cgtgaaccac cattagcctc ttgagcgact ttaaaagttc ttttagaagt ttttttctcc
     2281 agtttcgcct tatctaattc ctgcttaagg aagacccgct ttttattgtt cctatctaat
     2341 tcctgcttaa ggaagacctg ctttttaatt tcctctggac gaagtgactt tccttctttt
     2401 ccaagatttc ttccttgttt ctggatattc ttgtactctt tttggattct cttatactct
     2461 ttttgtattt tcttgacctt gttcttagaa gctcgaaatt ggcttcgact cttctttacc
     2521 aactgacgtt tagagtgagt ctgagattgt aacttcgtaa gttgttttgc gctatcttgt
     2581 tgaaccgttc ggtaattctt acgaactttt tctagctttc gatctaacct atgaccgatt
     2641 gtttttggtc tgcctttctc ctgatccata gtgagacccc taagcgtctg ttgcgactaa
     2701 gttatacaac ttagtattct ttggtattgg attttcaaat ggcactacaa ctggcccagc
     2761 tacgattaag ccagtacctt tagcttttgg ccgtgctaag tagcgaatct gtttatcagt
     2821 cagattgaca atctctttta ggatagccaa atcttggggc ttttgtttga gcaaaatcat
     2881 aaactcacta tttgagagca atttccgacc ttcttcaaca gcagccagcg tttctacgtt
     2941 ctgggtaatt cctgttggaa tcgcaccata tttccgaatc cgtgaatata acgtagtaaa
     3001 gaagtctgct tgagccttat ttttaaatag aatctgcatc tcatcaaagt aaacccaagt
     3061 agtacatttt ccttgatttt ctacaatttg attccagata taatcctgaa tcaccatcaa
     3121 agcgaacggc ttcaatttgt gcgacaactt cttcaggtta aagataacaa agcgatgatt
     3181 aagatccacg ttggtattgt gagcaaaaat atcctgagaa ccagttgtat aggtctctac
     3241 tgctaaagct aagtcttgtg cttcaggttc gggttgttct tttaagacct ggtgccactc
     3301 ttttaatgtt ggggtaaaat tctccgtcaa atagcgttca taagtcaccc ctgttacccg
     3361 gtcaataatc ccaatctggg catctgtcac ctctgacaga atcgattcaa acaatcccat
     3421 taataagttt gccttatctc caatcggatc gtcatcctca tcgtccaaac gatctagatc
     3481 tggtagatct aagagattga tatgtgtttt agatccaatc gaaatatcca ccatctgagc
     3541 accgaaagca cggccaatat cagaatattc atcttcggga tccacgatga tcactcggtc
     3601 ttctggatat ttcagtaaag ttggaataac ttctccaccc tttattgttg tagatttacc
     3661 agatcctgaa gaacctaaca caactcctga acccgtgttc aaatcacgct ttctatctag
     3721 tgtaatgata ttgtttgata actgattttg accatagtag cgagcgagtg agctttcaga
     3781 cttcaagtcc acgttggtaa aaggaacttg cgtagcaata ttagctgtcg tcatctttct
     3841 cataaaattc ttcttcacat tcaagaagca ctctccaata ggtaaaaccg tatttagagc
     3901 ctcttcttgg taataataga gatcttcaaa ctctacccct agcttccgtc cagcacgctt
     3961 aatcttctgc tcattccgtt gtagttcctc ctggttatcc gccttaaaat acactgcaat
     4021 caaaccagaa aagattttct ggtcatactc agtaatctcg tctcgccact tcttggtagc
     4081 ttctgagatt tcttggtcac gaccagcaac gaccgcatca tcaaagatac cagattgagc
     4141 cgccttacgt ttcgaacgta acttcccaat ttcagcatct gtctctgcat cgtcaatctt
     4201 ctctaagatt tcaacgttct catagggttc tgcatggata gtaatagcca gttccagccc
     4261 cagtgtcgtc aaatctcgaa taagccgatc agacatccag ttaggatagc gacgtgcata
     4321 gagcaccttg caccaacgat catctataat catgcgtttt tcttgaaatt caatcctgtt
     4381 tggcgcaata aatgatttag tgaataaacc tgtcaaagca atttctttgt aatcaaaatt
     4441 gacatacggg ttatctcgta acagttcaga aaagaccttt aggcgatcca aaccattcat
     4501 atccctgaaa gtaatatcag attcctgaaa ttgagttcct aaggaaactc caatatcttg
     4561 taggatcaac tgcgcctgct ttcggtcatc cgcattcgtt gaaatggtca catacttatg
     4621 tacctcgaag ttgttagcat gtgtcgtaaa tcgctccttg atcatctcat ttagctcctc
     4681 acgatagtcg tcaaaaccat catttgtttc ttcatacaag atattctgca aggagttatc
     4741 cgatactcga cggttaatga ctaagagctg gtagttacta ccctcatcca gtgaattaag
     4801 agcatccatc gttgtatcaa tgatactctc tttttcatct tgttgagcag ttgagtacga
     4861 agcatccccc aacataaagc tccgagaata cttctcacgt gcaatgtgca tcaatccgtc
     4921 ttcatggagc agtgtataat tgatggtgtt ttgtgtcgta ggtttcatct ggcgacgcaa
     4981 gcgatcaatt tttttctttt ctgctttttc tagtttttct cttttgcttt tgaataaact
     5041 catctttcgt atacattcct acctttccaa attctatctc ataggttcgt tgttggattc
     5101 ggaaaaagaa attgattttt tctttaatcc gcattcgctt agtcattccc gtaccgtaca
     5161 tccctccagg aacgacaaat agagcatccc aaagatagat gtaccaatca ggtagaccaa
     5221 agaagtaact agcagttgtc cctgagacag ctattatcaa acacaggtat agaacaagca
     5281 ttctactagt taagccaaat agaataggct tgtcctcagt ttcaaattct cttaaaaatt
     5341 ctgatccaat ttttttcaat tagtttcctt cccatcaaaa aaaaacagtc cgtttagaac
     5401 tgttagtctt atgtcattta tttatcacgt tcctttacaa gcatagctac agcaatctca
     5461 gattcctacc ccttcagtat cgaataggct tctgttagcc gttttttgtt cctgaaaata
     5521 gcgttcaaag ttttcatctc ctttgaagac cattttacca cgatccatat atttaatcca
     5581 ctgttccaaa cggtaaacat actctgtttg actgatacta tcagctatag cacagtacgt
     5641 tatatcttcc tgaagaaggg taagaattct catgccataa aaagcatctt gcttagcttc
     5701 tgcatagcgc caagcataaa tatatagttc gtcaccataa ctactcatcc gaacggcacg
     5761 aggaatctca gatatcttaa ctttaccatc caatatccac tccaataaag gctccgataa
     5821 taattcatgt tcataggcaa accaagaaag acgtgttatt tcttgttcaa gagaagttat
     5881 tttatccttc aactctcttg tcccatgttt cttttgtaaa tcattaaatt gtttatttcc
     5941 tatctccttt aacgtttcca ttgatagtca cctctttcta tagaaaacat ccacacgatt
     6001 ctctaaacat aggtaacatc gattaattct aatttttcta cacatagatt acactcctaa
     6061 aagctgcttg gcttttcgac tagatccaac cattacaaag atatagataa cccccttggc
     6121 aattgaagca aaggctgttc cccaggaatc actggaacca gtcgtaacct ttaggatatc
     6181 tgctgcaaca atcgaatcat aaacaacaga aacaataatt aggatgacac caataagggc
     6241 agaggctgca aagtatttca ggaagttaat cgtaacagat cgcaacgaat ccatcataaa
     6301 gaaggctact aacaatggag ctaaagcctt aagcatatat aaatccaagt aacgtaagaa
     6361 aacaataatc cctaaaataa cgttagctac tccacttaca gctttcccta cgaaagtaat
     6421 gatagttttt tcaactattc ctttcccacc agaaatatta gaatcaatgg ttgctttaac
     6481 agtaggtgtt acatgagcaa ttacctttac aataatatta agtaattcca gaatggcatc
     6541 gcaaatttga gatgaggcag aaatcatgat gaaggcaaat aaatacttca tcaaggcctc
     6601 tagccaaatc ttttgggtta gcgaacctcc tctggactta accatttgtg accacgatgc
     6661 catttcaaac cagaaaaaaa gacctaaaag gatataccca ataggtctga ctgcatcagc
     6721 catcatattt acagcttgat ttgtagcaga gccataacta gaaagagagc ttgttagctc
     6781 tctaatatct aaattcatag gctactccta aaattttagc tgtgataatg ctgcaacgac
     6841 tgcggccgca atccctgcag aagcaacagc caagaacgca ccattaatca tagaatcaga
     6901 cccatcatct tgtctttgct tatctttatt ctttcttcct tgaatataat caaccgcacc
     6961 attccagatc cagataagac ctgtgattgt tccaactaca cctagaccag taataatttt
     7021 tgtaatgatt tccattttgt tttacctctt ttaatttcat ttttttataa caaaaggcac
     7081 tgcagagatt tctacagtgc caaacacaat actattttta taattcttca aattcttcac
     7141 gataaatcgt ccgaacagta gctactagaa tactgaggcc aataataatt ggaacttcaa
     7201 aattcggata tgggaaaaat aaccctcctc cttttggtgc atcaaccact tgaccagcag
     7261 taataagtga atcatgggac attcctaaaa tatgcggtgt ataccatcca aaaatattat
     7321 caattatgtt ttcgcttggg aaattgaata gatgatgaat gattgccatt cccccaatca
     7381 atacgattgt tatacatatt ttagctataa cccacagaat aaacatacca atagtggatt
     7441 ttacaacatt aatacaccaa agaacgatat aaaagggagc tgtaaaaatt ctaatgatag
     7501 ctacccataa ccaggaaaaa tcacttccaa atttcataat cctactcctc cacgatttac
     7561 cgttattata ccataaaaat agcttatttt aaagattcct agagtattct aagcctcttt
     7621 tttcttgcgc ttgctgtaga gcaatcctga agcagcaccc cccattgcca gaccagctaa
     7681 cagcaattct gcagaagcct gctcacctgt agatggcagg cttcgttctg gttgttgcgg
     7741 atgttcttca ggagttttgg gctcttctgg agtctgagtc acaaccgtat tggaagcaac
     7801 ttccacaccg ttaactgtat gatagtaagt attttctact gctcctgact gaatgcgtgt
     7861 catttgtaga tatacttctg cttgaaactc tgatgtttct aaaatcgact ttaagagagc
     7921 atcatcaaag ctaatatcta ctttaccttt agccttgtct accacttgac ttgtgaactt
     7981 agttaattca tcaccagctt tgaatttttg gccatcactt gtttcaaaat ctacagcagc
     8041 aaataccttg taaacactct gataatcatc atgtgtttca tcgtagtcat cgctaaattt
     8101 atactcaaat aactgttctg agcgatcttt tggcactagg gaaccaacta atttgtaatt
     8161 aaatgtttga ttcagtttga cctcttttcc atccaagctt tctttgctta gatggtcgat
     8221 cacaacatct ttcttcggtt cgatctttgg tacattattg actactgttt cagttacata
     8281 atccatccca aaatcaattt gataggctgt attttcatac ttaccacctg tttgacccaa
     8341 ttccttctta acagtcattg gattggtaat ggtcagaact tctccagctt gcacgtaggt
     8401 cttgtagaat tcctctggat tctctgcctc gaatacttga atcgctcctt tcggagtgaa
     8461 atggctagac ttcagggctt cttggacacc tgatggtgcc ttagctagac tctcataaag
     8521 agacattttc aaatctttga ctacttgacc tttagaatcc gttacttgaa caccgtcttg
     8581 attgatggta acagcttctt ctggataatc atcaacgata tagaaccctt taccaatacg
     8641 gtctttatct gcttcaatgc ccttgtattg gctataatct gccgttacct tgtagtagtt
     8701 gacagagtct gccaatacct gtttcccatc gatgttcacg cctgctttat tcaaattctt
     8761 cttggtaggt ttaacagtag gaacattatt gacaactgta tctgtaatat aagctgaacc
     8821 aaaatcaagc tgataagctg tattctcata cttaccacct gtttgaccca attccttctt
     8881 gacagtcatt ggattggtaa tggtcagaac ttctccagct tgcacgtagg tcttgtagaa
     8941 ctcctctgga ttctctgcct cgaatacttg aatcgctcct ttcggagtga aatggctaga
     9001 cttcagggct tcttggacac ctgatggtgc cttatccaga ctatcataaa gagccatttt
     9061 caaaccttta actacttgac ctttagaatc cgttacttga acaccatctt gattgatggt
     9121 aacagcttct tctggataat catcaacgat atagaaccct ttgccaatac ggtctttatc
     9181 tgcttcaatg cccttgtatt ggctataatc tgccgttacc ttgtagtagt tgacagagcc
     9241 tgctaagacc tgtttcccat cgatgttcac acctgcttta ttcagatttt tcttggtagg
     9301 tttcgcagta ggaacattgt tctctacctt atccgtctgg tagccactac caaagtctaa
     9361 ttgataagct gtattctcat acttaccacc tgtttgaccc aattccttct taacagtcat
     9421 tgggttggta atggtcagaa cttctccagc ttgcacataa gtcttgtaga actcctctgg
     9481 attctctgcc tcgaatactt gaatcgctcc tttcggagtg aaatggctag actccaagga
     9541 ttcttgtaca cctgatggtg ccttatccag actatcataa agagccattt tcaaaccttt
     9601 gaccacttgc cctttagaat ccgtcacttg aacaccgtct tgattgatgg taacagcttc
     9661 ttctggataa tcatcaacga tatagaaccc tttgccaata cggtctttat ccgcttcaat
     9721 gcccttgtat tgactataat ctgccgttac cttgtagtag ttgacagagc ctgccaagac
     9781 ctgtttccca tcgatgttca cacctgcttt gttcaaattc tttttggttg gtttaacagt
     9841 aggaacatta ttgacaactg tatcagtttg atatccgtta ccaaaatcaa cttggtaagc
     9901 cgtattctca aatgattttc ctgtatttcg cagttcttcc ttagttacca ttggatcaat
     9961 aattgtaacc gattttcctg atttaatata ctggttaaaa taagcttctg gatcatccac
    10021 taaaaatact tggaaagcac ccttgggctt aatttcagaa ctagcaagaa aagctttaac
    10081 cttatcatta tcaacggcat ctatagaatc atactgatac accgagatac cagcaacttc
    10141 ttttccttcg ctgtcaatat aacgaatgtc cgattgatta atcgtaacag cctcttctgg
    10201 gtaatcatca attgctccga atccttttaa aatagtagat gaatctgcct tcatcccctt
    10261 atattgatca taatccaagg taatatggta gtaatttgtc gaaccaacta gaactggttt
    10321 accatcaatg ataactttat ccttattgta attatgttta agaggttgaa tgaaattatt
    10381 attcggattg tccggatcat tcggtttacc aggtgttgaa atctgaacaa tgtttgaata
    10441 acttgcgtac ttattgttaa tctttaattg gaagttattc ttgtaggtcg ctccatcatt
    10501 cgttacttta ccaactaaaa ttggagctgg tacttgtact tccttactta aatcttgatt
    10561 aagcttagat tttaaacttt ctaagccttt catccgaaca acatggctcg actcgtcata
    10621 agttaattca aaatctgagc taattttttt ggaagcttca acatctaaca caaaacctga
    10681 aggcaaggca tccacaattt caaagtctgt aatagcttca cgattagctg gaagaggctt
    10741 agttgttagt tcccactgta ctgttgaaag tttaggtaca tagcttttat caatagattc
    10801 accagaagaa ttttttacaa acttttctag gtcaggcatt gcctgtaagc gtgcatatct
    10861 aacccttact gttggagggg atactaaaga ggggatctct ttttccttta tctcctcagg
    10921 tttgggtggg agtacctctt caggttttcc agttggagaa ttgggtggag tagtttcaac
    10981 ttcataagtt ggtttgcgag gtggatttac tggtggaatg cttttcaact ccgccccctc
    11041 cccaagaatt gtgaagacaa cgttttgaac atttccactc aaattctctg catcccattc
    11101 agcgggagtt cttccctctg tcgaaccagg agatgatgtg tgaaggtacg ttaaactaga
    11161 accataccct actgaagcaa aggaagcctt aggaatatct gaggtatcat taactccatt
    11221 ttctactccc ttcataacgc gaccatcaaa atccaaacct gaaccacttg gattaagaac
    11281 cattccacga ccagatgagc cataactcaa atttgaacct tgaccccaat ctacatcggt
    11341 aataactgtt ccaattaaga gggaaacagg agttgtcgta ccttcaatat aaaaatcaaa
    11401 aaccatttcc aaacgggtat gattattata gacaaagtag aaacttccac catctccacc
    11461 cttgaggtag atatctgaat ctgtcacagg aacaccattt cgaacttctc cctgatagtc
    11521 tcctaaatcc gaaaccatga cttttgccat gatctttcta ccatctgtca acgttccaat
    11581 attatgaata taaaatgtat ctccaaatgt tggagattta atgatatcat aagtttccgt
    11641 actatcctta ctaactcgag ttcctgcgcc tcctgttaca taagtatctg catgataacc
    11701 taaaaaacca cgcatactct ctactggtag attatcatct ggtactactg taaaatcatt
    11761 ataatagtct aagcttcccc gaccagctga attatatcct ccataaactt tgaaacctgt
    11821 ttcagatcca aataaaggct tacttgtttg aattgcatct cgctcagctt taatagttgc
    11881 tagcttcttt gtatagtctg tcaaagagct ttcataagct cctctcttag cttcatttcg
    11941 ttttcggatt tctgcattct cttgattgat acgatctatt tctgcctgat tctctcgttg
    12001 atttttttca ttctctgcac gaatactagc attcttctga ttaattcgat tcacttcagc
    12061 ttgataagaa gttaaatcct tttgatattg ttccttcttc gcagtatttt catcttggat
    12121 tttctttcgg ttcgtttgat tttgtctttg atcttcacga tatttttcag tagctttctc
    12181 aatactatct gcttgtgtgc aataatcact ctcgacttcc ttttgctttt ttccaactca
    12241 gaggctgtac ttgcagttcc tttatctact acagaatcaa attccacctt caatccagct
    12301 tcttgtgcct ttcgaatagt ttcatctaaa ctggaatgag aaatagaaac ttctaacgtt
    12361 cctgtttttt cttcactctt tccttgattt tcagtagaaa tactgcttgg actcgtctgg
    12421 gcataaggcg catttgtagc cttattttca gttcgttcat ctgctataac tgggcttatc
    12481 atgcttaaag ctgctaaacc tagtatcact ccacaagttc cataaatttt tgatttccga
    12541 atagatccat atgtttttgt ttctcttgct ttgtgcattc tatctcctta tctaaaatat
    12601 caatcaatat aaaacctcaa atgttggctc tcgaggtctc ttataatata aaatcatctc
    12661 tttcctttcc aatagaaaaa agccagcttt cactgacttt tctatacaat attgtaatga
    12721 attttaagaa atccacttac cagaataatc taaataataa gcaccaatcg tctcattttg
    12781 tgccatctta ccatctgctt tcaaataata ccaagcactt ccgtccttga accattgatc
    12841 tctcagataa cttccatctg atttgagata gtaccaagct ttataactgg aatc
//
LOCUS       DAVDHZ010000057        11894 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000057 DAVDHZ010000000
VERSION     DAVDHZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.058"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(50..1252)
                     /gene="rpsA"
                     /locus_tag="VUR46_001961"
     CDS             complement(50..1252)
                     /gene="rpsA"
                     /locus_tag="VUR46_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET5457321.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1414..1485)
                     /locus_tag="VUR46_001962"
     tRNA            complement(1414..1485)
                     /locus_tag="VUR46_001962"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1451..1453),aa:Gln,seq:ttg)
     gene            complement(1495..1575)
                     /locus_tag="VUR46_001963"
     tRNA            complement(1495..1575)
                     /locus_tag="VUR46_001963"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1539..1541),aa:Tyr,seq:gta)
     gene            complement(1625..1855)
                     /locus_tag="VUR46_001964"
     CDS             complement(1625..1855)
                     /locus_tag="VUR46_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET5457322.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2023..2667)
                     /gene="pcp"
                     /locus_tag="VUR46_001965"
     CDS             complement(2023..2667)
                     /gene="pcp"
                     /locus_tag="VUR46_001965"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET5457323.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDVVLCIGQAGGRIGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYLSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2682..3605)
                     /locus_tag="VUR46_001966"
     CDS             complement(2682..3605)
                     /locus_tag="VUR46_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET5457324.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3602..4291)
                     /locus_tag="VUR46_001967"
     CDS             complement(3602..4291)
                     /locus_tag="VUR46_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET5457325.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4434..5033)
                     /locus_tag="VUR46_001968"
     CDS             complement(4434..5033)
                     /locus_tag="VUR46_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5457326.1"
                     /translation="MACGKTDKEADAPTTFSYVYAVDPASLDYSIATRTSTTDVIGNV
                     IDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQEPASYLNIMDPKSGSAMKHLGITKGK
                     DKDVVAKSGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMPTASFGGSPV
                     VSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYN"
     gene            complement(5116..6138)
                     /locus_tag="VUR46_001969"
     CDS             complement(5116..6138)
                     /locus_tag="VUR46_001969"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET5457327.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAQFKNGQWNQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVIRANEEYVPPYGTGGTLYLRPLLIGIGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTDFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPVEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTCKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6273..8744)
                     /gene="parC"
                     /locus_tag="VUR46_001970"
     CDS             complement(6273..8744)
                     /gene="parC"
                     /locus_tag="VUR46_001970"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET5457328.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDLFSTEVEENDQTLLVQSNKGTIYENRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLKEVFTEAK"
     gene            complement(9164..11107)
                     /gene="parE"
                     /locus_tag="VUR46_001971"
     CDS             complement(9164..11107)
                     /gene="parE"
                     /locus_tag="VUR46_001971"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET5457329.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLVAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRREWIEDNVKFTLEEATVF"
     gene            11243..11884
                     /gene="plsY"
                     /locus_tag="VUR46_001972"
     CDS             11243..11884
                     /gene="plsY"
                     /locus_tag="VUR46_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET5457330.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3417 a         2692 c         2092 g         3693 t
ORIGIN      
        1 aaaaatccct tgtttagtaa acaaaggatt ttgtgaattt tcaatttgat taaagttcga
       61 tatcaccaaa caaatcagcc attgaaaatc ctgtttgtgt ttctggaagt tcgaaatcac
      121 gcttttcttg acgtcttgga cgacgtggac gagcagcacg tttttcttct ttttgtcctt
      181 cttcttgggc tggacgttct tcaagagctt taatagaaag tgacacgcgt tctgcatctg
      241 cgttaacttc aagaacttta acttgaactt cttgaccaac tttaagagct tcttttggat
      301 tttcaatccg tttgtgtgaa atttgtgata cgtgaacaag tccatcgata cctggcaata
      361 cttcaacaaa tgcaccgaag tcagtcaaac gtttaactgt tccttctact acatcacctt
      421 tagccaattt ttgctcaacg ccatcccatg gtcctggtac tgttgcttta agtgaaagtg
      481 atacacgtcc ttcttcttcg ttaagatcaa ggattttcac ttcaatttct tcaccaacag
      541 ttacaactga ttttggtgat acgttacgtt catgtgacaa ttcagtcaag tgaaccaatc
      601 cgtcaacacc accaaggtcg atgaaagcgc cgaagcttgt gatacgagca actttaccag
      661 ttacaacatc accaacagcc aatttaccga atacttcagc gcgagctgct gcagtagctg
      721 cttcaacaac ttcacgacgt gaaaggatga agcggttttc tttagcgtta acttctttga
      781 ttttagtatc aaattcttga cctacaaaac gctcagcgtt acgtacgaaa cgagtatcca
      841 acattgaagc tgggataaat ccacgaacac cttcaaattc tactgaaagt ccacctttaa
      901 cggcacgcgt tcctttaaca gtaacaactt cttcttcgcg accaacaagt ttgtcccatg
      961 ctttgcgagc ttcaaggcgt tttttagata caaggtatgt aactgtatca gtatctttac
     1021 caactacttg acgaagtaca agaacatcca atacttctcc tactttaaca aagtcattga
     1081 tatctgcatc acgatcgttt gtcaattcgc gaagagtcaa gacaccttca acaccagttc
     1141 cagagattgc aacgttagct tgagtcgcat caactgtcaa tacttcagca ctaacaacat
     1201 caccagtctc aacttgacta acgctattta gcaaatcttc aaattcgttc atctaaaaaa
     1261 tcctccaaca atcaagtttt tcttaaactt gacatactta taattttttt cctaagcacc
     1321 cgcaaggaca tgtttatatc attcacgtct ttcaattata aaaataaaat accctaagat
     1381 attttgcttt ttatcttgat tattacctaa gaactggggt agctggattc gaaccaacgc
     1441 atgagggagt caaagtccct tgccttaccg cttggctata ccccattaat gaaatggaga
     1501 gagagggatt cgaacccccg aacccgaagg agcggattta cagtccgccg cgtttagcct
     1561 cttcgctatc tctcctacaa tcaacatgga ctattatatc atgaaaattt caaaaaaaca
     1621 agacttattt tgctaaatta taattttcaa tcaaaatttc cacagctttt tccaattttt
     1681 tataaaaact atcgacattc ccattcttta taatggcaaa ttgtccgtct aattcggcaa
     1741 tttctccgat aactttttta ccgatagtca atgtataacc ttcaaaactg tctttaccaa
     1801 cattaacttt ggcatccgct acttgaattt cgattttttt atctttcttg ctcatttcat
     1861 acctctcttc actttttcta ttttacaaga aaatcctaaa actagcaaga aaaaactcta
     1921 tatcaggctt ctctgatata gagttttatg taaacaacct caatcgattt agcatagtta
     1981 atagttagta aacaagcata attgactatc ctttttaggt tatcagtgag tctcaccgcc
     2041 tactaactgc aaatccttat ctttgtagtc tacaatagct tcaatagcta cctctatgcc
     2101 tcttacaata tcacatagac tcattcctgc agtattcggc ttatttacta cttgttccat
     2161 catatatgga atatgcatga aacctgctct catattaggg aattttttat ccactaaata
     2221 aagagcttgg tacatcaaat gattgcaaac aaaggttcct gcactattgg atacaactgc
     2281 cggaagtccc tgttttttga tagcttgtac catcgctttg ataggtaaac tacttaaata
     2341 ggccgatgct ccatcaatac gaatcggtgt atcaattggt tgattgcctt cgttatcagg
     2401 tatgcgagca tcatcttgat taatagccac tcgttcaggt gttaagccga tcctgccgcc
     2461 tgcttgtcca atacaaagta caacatctgg ttgatatcgt aatatttctg cctctaaaac
     2521 ttctgacgac ttataaaaaa ccgttggaat ttctacccag cgaacttcag ccccattaat
     2581 ctcagatggt aataatttta cagcctccaa agctggatta atcttttcac ctccaaaagg
     2641 attaaaacct gtaaccaata ttttcatttt attttccttt actaaaatgc gagaaagtac
     2701 attaagaata tgtgaataac aatcattact agagcaacac ctgcttgagc ctttataacg
     2761 ccattctgat ctttcatatc catcaatgct gctggtagag cgttaaaatt agcagccatt
     2821 ggggtcaata aggtcccaca ataacctgct gtcatggcaa gagcaccagc cacaattgga
     2881 ttagctccca gagcaaatac aaagggaact ccaacacctg ctgtaataac ggtgaatgct
     2941 gcaaaagcat ttcccataat cattgtgaat agaaccattc caagaacata ggccaaaact
     3001 cctataaagc gactatctga aggaacaata ccgctaatca gatgagagat aacatcacca
     3061 acacctgcta cagtaaaaat agcccccaaa gcccctaata attgaggaac aatcccactt
     3121 gttgaaactt gctgagtcat tcgattattt tctgataaca gactcttagg gtgactattg
     3181 gtaatcacaa gaacagaaat tgtagcaaac aaggcggcaa ggctaatcga aatcttgcta
     3241 aattctggaa tcatttgcgc taagaccaac gcaagtattg ccatcagcat aactggaata
     3301 aaaattttat ttttcaacct gttagattca atattggctt tcatttcatc taaggatggc
     3361 aaggttccga tacggacttg cttaaacaat gttaacagcg ataataggat tacaataata
     3421 ccaatactca tatttggcat ataggaacca cctataaacg taatagacaa tagagtccaa
     3481 aatgcagatg tcccaagtcg aactgggttt gttttatctt tataactaca ataggctgta
     3541 tggagaaatt gacaaccaat cacaatatag gtcaactcta atagttgctt tgccaactct
     3601 gtcatttttg ttctcctccc ctagtctttt ttgatatcaa ttttttatca aataaataat
     3661 tgtaaatccc tactacaata agtgttataa cagcaacaat aatagatgta gaagcaatcc
     3721 ctgcataatt gctttcatag cctaactgat ctaatgttcc ccctatcaag aggactcccc
     3781 cagcacctac aaacgtattt tgagcaaaga aatttccaaa attttcattc gcagccgcac
     3841 gcgcttttat tgtctcatct tcaacctctg ttaactttct acctaattga gactctgcag
     3901 ctgcttctcc cataggttga accaaaggtc tgacaaactg agggtgtcct cctagacgaa
     3961 ttgaaaagaa accagctaac tctcgaataa agaaataaac tgtatagaag tttccaactg
     4021 tcagaccttt aatctttcga atcaaatcga ttgatcgttg cttgagtcca aaggtttctg
     4081 acagccccac aagaggcaag gtaaccataa aaatcgtgag cactcgctga ttgctaaatt
     4141 cttttcccaa aatctccaaa aattcaacga gagaaacacc tgaaactaaa gctgtaacca
     4201 aaccagctaa gactactgtt gcaattgtat caaattttaa aataaaaccc acaacaataa
     4261 ttgctattcc tattaatcta atccactcca tatcaaactc ctttatattc aaaatgacag
     4321 tatttttaaa attttatcaa gatcaatacc attccttatt taatgtgttt ttctagttct
     4381 ttttggtatt tgctattgga ttccaatttt tctttttgcc attttttaaa aacctagtta
     4441 tattcttttg ttgtaacaat atctttttgc aatttcattc ctttaaagat atatggatcc
     4501 cccttaatac caacttgtga gtatggtttt gagaatggta ctacgttact tacaactgga
     4561 gaaccaccaa atgaagctgt tggcatcaat aatgaactat ctgtcgacca agcttgagct
     4621 ttggcatatt tttcatatct cttctctagg tcagtagtct cagaaacagc atcttctaac
     4681 aatttcttat atttatccaa accagattta gctacaacat ccttatcttt tcctttcgta
     4741 ataccaaggt gtttcatggc agaaccagat tttggatcca taatattcaa gtaagacgct
     4801 ggttcttgat agcttggagc ccatcctgta ctgttcaaat catagtcttt ttgagaagga
     4861 gcaacattgc cgtatttatc attttccatc aagccatcaa taacatttcc aataacgtct
     4921 gtcgtcgatg ttcgagtcgc tatactgtag tccaatgatg ctggatctac tgcatagaca
     4981 taagaaaatg ttgtcggtgc atctgcttct ttatcagttt ttccacaagc cactaaaata
     5041 gctgtcgtgc tcaggaccgc tcctgctgtt aagagtcact ttttcgattt cataaaaaat
     5101 ctattttggt ttattttaat ctacttttac aatccaacct tctggcgctt caatatcgcc
     5161 aaactgaata cccgtcaatt cattatataa tttacaagtc acaggaccta cttctgtttc
     5221 actatagaat acatggaaat catcaccgtg ttgaatacct ccaattggag aaataaccgc
     5281 tgctgtacca caggcacctg cctctacaaa acggtcaaga ttatcaattg gaacatcacc
     5341 ctcaacagga gttaatccca agcgatgttc tgccaaataa agcaaggaat acttggtaat
     5401 agatggcaag atagatggac tcaatggtgt tacaaattca ttatcagctg taattccaaa
     5461 gaagttagct gatccgactt cttcaatctt tgtatgagtt gatgggtcca gatagataac
     5521 atctgagaaa tgacgtgact tggccatttt tcctggtaag agacttgcag catagtttcc
     5581 accaacctta gccgcacctg taccatttgg tgctgcacgg tcgtattcat cctgaatcaa
     5641 gaagtcggtt gggaccaaac cacccttaaa gtaatttcca actggcatag caaagatagt
     5701 aaaaatatac tcctctgctg gttttacccc gataatatct ccgataccaa tcaaaagagg
     5761 gcgaagatag agggttccac ctgttccgta tggtggtacg tattcttcat tcgcacgaat
     5821 aactgcttta caagcttcta caaacatgtc tgtcggaact tgtggcatca agagacggtc
     5881 acatgtacgt tgcaggcgtt tggcattttc gtcaggacgg aacagttgaa cactgccatc
     5941 cttagtacga taagctttca aaccttcaaa tgcttgttga ccatagtgaa gacttggaga
     6001 agactctgaa atatgcaaag ttgcatcctc tgtaagttct ccttgattcc attgtccatt
     6061 tttaaactga gcaagatagc gataaggtaa tttcatatag gaaaaaccga ggttttccca
     6121 atcaatcgtt actgtcatat tccactcctt attctaaaaa cctatttctt atattctaca
     6181 ctatttttct aaaatagcaa gtctgttttg taattttcag aaaatttctc caataacaag
     6241 aaccagctct tagaactgat tcttcatttc acttatttag cttcagtaaa tacttcttta
     6301 agataagcgt caaaaacttc ttcatctgaa atcgtgtcag aaatgaagct tccgttgcta
     6361 gtcctttctg acaggttcaa gtcttgcaat ctgttttcat agattgttcc tttgttggat
     6421 tgaacaagca gcgtttggtc gttctcttct acttctgtac tgaagagatc gccaacaaat
     6481 ccttgctctg caactgctcc tgccaagaag acacgatgcg gtttgttttt caactcacgc
     6541 aagacttgta atcctcgttt ggcacggctg gttgctagaa tttcctcaat ggaaacacgt
     6601 ttcaagcttc cacgctgggt caagaggtag aaggacgaag tattacagat aaagccagat
     6661 tggaggacat catcttcttt caaattcata gccttgacac ctgctgcctt agcaccgaca
     6721 accggaacct cttcgatatt gaaacgcagg gcataaccat tttgactaac caagacaaca
     6781 tcatctagtt taatcggagc cactgctaca atctgatctg tatcgtcttt gagcttagca
     6841 tacttgacag acttagatct ataggtccgc catggagtga attcttttcg ctctacccgt
     6901 ttgatttgac caaggcgagt cactgcaaag taggttgtcg catcgtcaaa ctgatccagt
     6961 acttccacat aaaggatttc ttcattcgtt tcaaagtttg tgatggtttg gctcagatgc
     7021 tctccgatgt ccttccaacg aatatctgcc aactcatgga ttggtctgta gatgacattt
     7081 ccaagacttg tgaacatcaa gaggtgctgg gttgtcttgg cagattgaac aaaaatcaaa
     7141 cggtcatcat cacgcttgcc aatttcttcc aaggtggaag ccgcaaagga acgtggactg
     7201 gtacgcttga tgtaacctgc cttggtcacg ctgacgtagg tatcttcctc agcgataaga
     7261 ctagctgtat caatctcaat tgctttcgca gtgtcttcta aagaactcaa acgaggagtt
     7321 gcaaatttct tcttgacctc acgaagttct ttcttcatga gattgtacat agtcctttca
     7381 tcaccgataa tagccgccag catagcaatc ttctcacgaa gctctgcttc ttcttcctgc
     7441 aagacaacca catcggtatt ggtcaaacgg tacagttgca aagttacgat agcctcagcc
     7501 tgttcttccg taaaatcata gctaactttg aggttttcct tggcgtccgc cttattctca
     7561 gaagcacgga taagagcaat gacttcatcc aaaatcgaaa tcacacgaat caaaccttcg
     7621 acgatatgga gacgtttctc agccttttct ttgtcaaagc gtgaacgcgc caaaatcact
     7681 tctcgacggt gagcgatgta gctagacagg attggaacaa tcccaacctg acgaggtgtg
     7741 aaattgtcaa tcgccaccat attaaagttg tagttgattt gtaggtcggt gtacttaaat
     7801 aagtaattga gaacaagctc agtattagcg tctttcttaa gttcaatagc gatacgaaga
     7861 ccatcacggt cagactcatc acgaacctca gcaatcccag ctaccttgtt attaacacga
     7921 acatcatcga ttttcttgac tagattggcc ttattgattt cataaggaat ctcagtaata
     7981 acgatttgtt ccttaccacc ttttagcttt tcaatttcag tcttggaacg aacaaccacg
     8041 cgccctttcc cagtctcata agctttcttg atttcatcac gaccctgaat aatagcccct
     8101 gtagggaagt ctggtccagg taagaattcc atgagtttat caatctttgc agttgggtgg
     8161 tcaatcatgt aaactgcagc atctatgacc tcagctaaat tatggggagg aatgtctgtg
     8221 gcataaccag ccgaaatccc agtcgaacca ttgaccaaga ggtttggaaa ggctgctggc
     8281 aagaccgttg gttctttctc cgtatcgtca aagttccatg caaaaggaac tgtctttttc
     8341 tcgatatcct gaagaaggta gcctgcaatt tcagacaaac gtgcctcagt ataacgcata
     8401 gctgcaggag gatctccgtc catagaaccg ttattaccgt gcatttcaac tagaatctca
     8461 cgatttttcc agttctgtga catacgaacc atggcatcat agatagaaga atccccgtgt
     8521 gggtggaaat tccccatgat gttcccgact gacttagccg acttacggta gctcttgtca
     8581 aaagtattgc tatccttatt catagaataa agaatacggc gctgaaccgg cttcaaccca
     8641 tcacgaatat ctggcaaagc ccggtcttga ataatgtact tggagtagcg accaaagcgc
     8701 tctcccatga tgtcctccag ggacatgttt tgaatgttag acataagata caaagcccat
     8761 aaaataccaa gtaaaaatag aaaattcttg aagtaagcaa actcacaaga gaatttatct
     8821 ttttcacaca gtatctaggg cgtgttcaac tcctttcaaa gaatgtagag taggttttta
     8881 tgcagtaaaa gatattttac gggaattcct cccgtgttca gttacgataa gtaaccaaac
     8941 tatcctgttt gtatttttca atatgaaaat ctggttttcc aaaattagtc ttagtttgtg
     9001 tcttagccgc tcccttaagc gcctctttga gataagcact catagcagat tcttcattaa
     9061 taatcctgca attttttcaa accaagattt tcaaactgct ttttcacata gtcattcaca
     9121 tccgactcta atttccagtt tactaacata ttattttctt tcattaaaac actgtcgctt
     9181 cttctagcgt aaacttgaca ttatcttcaa tccattcacg gcgtggttct accttatctc
     9241 ccatgagaac attgacgcgg cgttcggcgc gcgctaaatc ttcaattgtg acacggatga
     9301 gggtacgtgt ttctgggttc atggttgttt cccagagctg gtccgcattc atctcaccaa
     9361 gtcctttgta tcgttggagg gtagcgcctt taccgaactg tttacggagt tcttctagtt
     9421 ctccgtccgt ccaagcgtag gccacttctt ctttcttgcc tttacctttg gacatcttgt
     9481 aaagaggtgg gagggcaata tagacatgac ctgcctcgac tagcggacgc atgtaacggt
     9541 agaaaaatgt caagagcaag gtctggatat gggcaccgtc ggtatccgca tcggtcatga
     9601 taatgatctt atcatagttg gcatcttcaa tagagaagtc tgctccaaca cccgcaccaa
     9661 tggtataaat catggtattg atctcttcat ttttgaggat atccgccatc ttggccttgg
     9721 ctgtattgac aaccttacca cgaagaggta gaatagcctg gaacttgcgg tcacgacctt
     9781 gtttggcaga accaccggca gagtccccct caactagata gagttcattc ttagcaggat
     9841 tcttagattg ggctggggtc aatttcccag acaacaagcc cttatctttc ttgtttttct
     9901 tcccatttcg gctctcatca cgcgccttac gtgctgcttc acgagcatca cgggccttga
     9961 tagccttgcg gatgaggtta gaagctaatt ccccattttc cataaggaaa aaggtcaact
    10021 tatcagccac tattccatcc acaactgggc gagctagggg gcttcctagt ttatccttgg
    10081 tctgtccttc aaactgcaag tgttcttcag gaactaagat agaaagaacg gccactagtc
    10141 cctcacgata gtctgaacct tcaaggtttt tatctttttc cttaagaaga cctgttttac
    10201 gtgcatagtc attcatgacc ttggtaatgg cagacttgag tcctgtctcg tgcgttccac
    10261 cgtccttggt gcgaacgtta ttgacaaagg atagaatgtt atctgagaat ccgtcattgt
    10321 actggagggc tacttccact tgaaaaccat tgtcttcccc ttcaaagtaa agaactggcg
    10381 tcaagatttc cttatcttcg ttgagataag aaacaaaatc ttgtactcca ttctcatagt
    10441 ggaactcaat cgcttcatct gttcgcttgt ccgttaaaga caaggtcaca tttttcaaga
    10501 gaaaggctga ttcattaagg cgctctgaaa tggtattgta cttgaaatct gtcgtagaaa
    10561 agatagtcgc gtcaggcata aaagtaactt tggtgcctgt tttagacttg ggtgctgtac
    10621 cgattttctt caaagtcgtg acaggttttc caccattttc gaaacgttgc ttgtaaactg
    10681 cgccatcacg ggtaatttca acttctaacc agctagaaag ggcgttaaca acggaagaac
    10741 ccactccgtg aagtccacct gatgtcttat agccaccttg accgaatttc cctccggcat
    10801 gaagaatggt aaagataacc tcaacagttg gaattcccat agcgtgcata cctgtcggca
    10861 tcccacgtcc atggtcttga accgttagac taccgtcttt attgatagtt acatcgatac
    10921 gatcaccaaa cccagacaag gcttcatcga ctgcattatc aacgatttcc caaactaggt
    10981 gatgaagacc agcgccatcg gtcgatccaa tatacatccc tggacgtttt cggaccgcat
    11041 ccaacccttc tagcacctga atagcatcat cattataatt gttaatattg atttcctttt
    11101 ttgacacaag gaacctccta ttcgttcatc tttactattc tacaggtttt ccaaggattt
    11161 tgcaaaattt ttctttctcc gatgtgacaa tttcagcaga gattctctgc ttttctttcc
    11221 caattcatga tataatagga gtatgattac aatagtttta ttaatcctag cctatctgct
    11281 gggttcgatt ccatctggtc tctggattgg acaagtattc tttcaaatca atctacgcga
    11341 gcatggttct ggtaacactg gaacgaccaa taccttccgc attttaggta agaaagctgg
    11401 tatggcaacc tttgtgattg actttttcaa aggaacccta gcaacgctgc ttccgattat
    11461 ttttcatcta caaggcgttt ctcctctcat ctttggactt ttggctgtta tcggccatac
    11521 cttccctatc tttgcaggat ttaaaggtgg taaggctgtc gcaaccagtg ctggagtgat
    11581 tttcggattt gcgcctatct tctgtctcta ccttgcgatt atcttctttg gagctctcta
    11641 tcttggcagt atgatttcac tgtctagtgt cacagcatcg atcgcggctg ttatcggggt
    11701 tctgctcttt ccactttttg gttttatcct gagtaactat gactctctct tcatcgctat
    11761 tatcttagca cttgctagtt tgattatcat tcgtcataag gacaatatag ctcgtatcaa
    11821 aaataaaact gaaaatttgg tcccttgggg attgaaccta actcatcaag atcctaaaaa
    11881 ataaaacgcc agtt
//
LOCUS       DAVDHZ010000058        10827 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000058 DAVDHZ010000000
VERSION     DAVDHZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.059"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(71..1282)
                     /locus_tag="VUR46_001973"
     CDS             complement(71..1282)
                     /locus_tag="VUR46_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET5457331.1"
                     /translation="MNNKTKKFTLATVLVLSLLGAGTLTSQSVVANDRLVSTQEINGQ
                     SYNILNSEVTSTSSGTTLVGIEGTFLTPDKQAILDRINAIRKEAADEGLVTSYVPIKW
                     STALEKTAFVRAAEASITIDHTRLSSKDIWTSWPAGNFSLSENLAWNYNGFMKAIQQW
                     YDEKADYVKSRSGVSVAGQTGHYKSLIDPKLTYMGLAAFENPVTQNGWITVAQSFGTA
                     SGGSEELAGSYGKAIQYTEANSSQIQTFATKANLFDKDLKAIRTHKTKNENTNSSQKN
                     EFNHSQYFGSWIQSNGRWWFKHNDGSYTSNGWEKINRTWYRFDNSGWMQTGWVKDGSW
                     YYLDGSGAMKTSWVKDNGSWYYLQDSGAMKTGWMKVSGKWYYAYSSGALAINTTTPDG
                     YRVNYNGEWVG"
     gene            1629..2581
                     /locus_tag="VUR46_001974"
                     /pseudo
     CDS             1629..2581
                     /locus_tag="VUR46_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2654..2938)
                     /locus_tag="VUR46_001975"
     CDS             complement(2654..2938)
                     /locus_tag="VUR46_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET5457332.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2992..3927)
                     /locus_tag="VUR46_001976"
     CDS             complement(2992..3927)
                     /locus_tag="VUR46_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET5457333.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            4031..4474
                     /locus_tag="VUR46_001977"
     CDS             4031..4474
                     /locus_tag="VUR46_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET5457334.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLETDIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIECLEQFAEELAAKVG"
     gene            4590..4856
                     /locus_tag="VUR46_001978"
     CDS             4590..4856
                     /locus_tag="VUR46_001978"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET5457335.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            4853..5227
                     /gene="crcB"
                     /locus_tag="VUR46_001979"
     CDS             4853..5227
                     /gene="crcB"
                     /locus_tag="VUR46_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET5457336.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            5221..5550
                     /gene="crcB"
                     /locus_tag="VUR46_001980"
     CDS             5221..5550
                     /gene="crcB"
                     /locus_tag="VUR46_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET5457337.1"
                     /translation="MVIVYLAIACGFGALVRYLFSRYNQASKMPLGTLIANLLGCLLI
                     GLFYNHVESKEVYAILATGFCGSLTTFSTLNDELQRLLSDKKVFYSYLILTYLGGLVA
                     IFLGILL"
     gene            5669..6016
                     /gene="rplS"
                     /locus_tag="VUR46_001981"
     CDS             5669..6016
                     /gene="rplS"
                     /locus_tag="VUR46_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET5457338.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            6058..6129
                     /locus_tag="VUR46_001982"
     tRNA            6058..6129
                     /locus_tag="VUR46_001982"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6091..6093,aa:Arg,seq:cct)
     gene            6296..6463
                     /locus_tag="VUR46_001983"
     CDS             6296..6463
                     /locus_tag="VUR46_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457339.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(6695..7549)
                     /locus_tag="VUR46_001984"
     CDS             complement(6695..7549)
                     /locus_tag="VUR46_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5457340.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     NHFYILLNRLGISFSEFEELVHCYYSKKECLFEELEHAVNSSDIFLLQELVDKIELKQ
                     KQEKSLCNYHIKLIAEQQINRLANLPYNSSKCNELIKYLLSVDTWMEYELKLFYNSVF
                     FMNTKTISLLYRIVIKKTRYFLKTNTGTHRIIPLYLFNLKLLLKNNLLDSAQFFIDDL
                     ENLLTRQGYYFEKNYLLFLKGIYLIKTNQIELGKKECSKAMRIFKEYNDSDTINELNQ
                     KFKLDLTI"
     gene            7643..8863
                     /locus_tag="VUR46_001985"
     CDS             7643..8863
                     /locus_tag="VUR46_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HET5457341.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFSNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEEASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            8876..9994
                     /locus_tag="VUR46_001986"
     CDS             8876..9994
                     /locus_tag="VUR46_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5457342.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREEGTLNLIKPGRIVRQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYAFKSSGAMISADWLYDNGSWYYLKDSGSMVTG
                     WLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSMATGWVKDSGSWYYLKNSGSMA
                     TGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAWK"
     gene            10480..10749
                     /locus_tag="VUR46_001987"
                     /pseudo
     CDS             10480..10749
                     /locus_tag="VUR46_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
BASE COUNT         3443 a         1761 c         2145 g         3478 t
ORIGIN      
        1 atctctatac tatctgaaag tgaagattac tcactgtgag atagtataga gtctttttgt
       61 tgtagttaaa ttatcccacc cattccccat tgtaattgac acgataaccg tcaggtgtag
      121 ttgtattgat tgctagggca ccagagctat aggcatagta ccatttgcca gatactttca
      181 tccagcctgt tttcatagca cctgaatctt gaaggtagta ccagctacca ttatctttga
      241 cccaacttgt cttcatcgca cctgagccgt cgagatagta ccaactaccg tcttttaccc
      301 agcctgtttg catccaacca gagttgtcaa agcgatacca agttctattt attttttccc
      361 atccattact cgtgtatgag ccgtcattgt gtttaaacca ccaacgtccg tttgattgaa
      421 tccaacttcc gaagtattgg gaatgattga actcattttt ctgacttgaa tttgtatttt
      481 catttttagt tttatgagtt ctgatagcct ttaagtcttt gtcaaaaaga tttgccttag
      541 tcgcaaatgt ttgaatctga gaagaatttg cttctgtgta ttgaatggct tttccataac
      601 taccagctag ttcttcagag ccaccagatg ctgttccgaa actttgtgca acggtaatcc
      661 atccattttg agtgacaggg ttttcaaagg ctgcaagccc catataggtc agttttggat
      721 caattaagga tttatagtgt ccagtttgac ctgcaacact gacaccacta cgagatttaa
      781 cataatcggc tttttcatca taccattgct ggatggcctt cataaatcca ttgtagttcc
      841 aagccaaatt ttctgaaagg gagaaatttc ctgcaggcca ggaagtccaa atatccttgc
      901 tagacaagcg tgtgtgatca atggtgatcg aagcttctgc tgcacgaaca aaggcagttt
      961 tttctagtgc agttgaccat ttgatgggaa catagctagt aactagacct tcatctgccg
     1021 cctcttttcg aatggcattg atacggtcta agatagcctg tttatctggc gttaagaaag
     1081 ttccttcaat cccaactaga gtagtaccag aagaagtgct agtaacctca gagttcaaga
     1141 tattgtagga ttgaccattg atttcttgag tggaaaccag cctatcatta gcgactactg
     1201 attgtgatgt aagagttcca gctcctaaca aggaaagtac taaaactgta gcaagtgtga
     1261 actttttagt tttattgttc attttgtgtc ctcctatttt tattataaca tctttactgg
     1321 gtagagtaaa ctaaaattcg gtatagctag ggactatatt tattttaaat tgaaagttct
     1381 ataatgaagt tagccaccca ggcctcctaa aaattagatg ttttaactag cttatagcta
     1441 gtactcgatt tcatttgata agaggcttgg agctgttagg ctgacaagac aaggataaga
     1501 ttagccttgg tttagctgac aaaactgctt caagggttcc tcttgtcaaa tgaaagctct
     1561 tctaggcata agaaaacacc tctgtgttat acttgttgtt caaccacaaa cacaagaaag
     1621 gcacagagat gcaaaaccat tatactacaa aagccaaaca tttgacaatc gatagtcgtc
     1681 gcttaatcga acgatggaaa aaggaaggga aatcaaatag agaaatcgcc tctctgcttg
     1741 gaaaagctcc tcaaactatc catactgaaa tcaagcgtgg gacaatccga caatgtcttg
     1801 gaaaagggcg ctttaaagag gtttattctg ccgactatgc tcaacagtct tatgaaaata
     1861 atcgcaagcg ctcgatcaag aaatcaagat tgaacaagga gctgaaggaa aagattctcc
     1921 actatcataa ccaaaagttt tctcctgaaa tgatggtcaa ggctaagggc gttaacgtgg
     1981 gaatttttac catctactac tggatccatc atggaaaatt aggattgtca aaacaggatc
     2041 tgctctatcc tagaaaagga aaatctgtta agaaacaagc tagcaccaat tttaaccccc
     2101 ctggtcaatc caatctatcg aacagcgtcc tgaagctatc aatctgcgat tggagaatgg
     2161 gcattatgag attgatacgg ttctgcttac aagagtgaaa aattattgtt tactggtctt
     2221 aactgatcga aggactaggc atcaaattat ccgattgatt ccaaataaaa gtgctgaggc
     2281 ggtcaatcag gctttaaaac tcatcttaaa acaacaacaa attctttcca tcacggcaga
     2341 taatggtaca gaatttaacc gcttgtctga tgtattttct gaggaacata tctattatgc
     2401 gcacccctat gcctcttggg aaaggggaac taatgagaat cacaacaggc tcattcgtag
     2461 atggttacct aagggaacta agaaaacgac tcccaaagaa gtcgcattca tcgaaaattg
     2521 gattaataac tatcctaaaa aatgcttgaa ctacaaatca cccagagaag acttcttgat
     2581 ggctaacttg aacttgaaat ttggcgttga tttcaagaaa caaaaaagaa cagccgaaac
     2641 tgttctctta tcattatttg agaccgtatt ttttgttgaa acgatccacg cgtccatctg
     2701 cttgagtgaa cttttgacgt ccagtgtaga atgggtgtga gtctgatgaa atttccacac
     2761 ggatcaatgg gtaagtctcg ccttcgaact caactgtttc gttagagcgt tttgttgaac
     2821 cgctaaggaa ttggtaacca gtagttgtgt ccatgaagac aactgggcga tattctggat
     2881 ggatatcttt tttcattttg caatatttcc tttctgccat ggtctctttg cgagccatag
     2941 attgttacca tactagtcta tcagattctg aaaagtttgg caagtatttt atcagttttt
     3001 aagcaagttt tttaactttt ggtagatgat ttcgttttcc tctaggctat aggaattagc
     3061 accacttgct agagggtggc ctccaccatc atgttccttg gcaatttcat tgataggatg
     3121 gattttactg cgtaagcgaa cgcggtagtg gccatcagcc tgttccacaa aaattcccca
     3181 gagactaaca ctatcaatac gcccaggtgc acctacaatg gccgcagttt cagcatcggt
     3241 tacattgtat tgtttcaaga ttttctgact caggataacg cgagcagcac cattttcatc
     3301 cacttccaga tggtcgtaga tgtagccttg cagtttagca attttgtagc tcatagtgtc
     3361 cattttgcga gtgagagccg caaagtcaaa gttatgttct ctcaaataag cagccaggcg
     3421 aagagtccgt gcagtggtag aagggtagag gaagcgacct gtatcaccga caattcctgc
     3481 aaagagcaac tcagcatcgc gatctgccaa ggctagttgg gttgtttggg caaatagggt
     3541 aatcatctcg ctagcgctac ttgaactagt atcgacccaa gacaggtcac cgtatacatc
     3601 atcatttgga tggtggtcaa tcttaatgag aaaatcacct tgactatagc gcttatcatc
     3661 gatacgagca gtattagctg tatcacagac gatgacaagt gcgccttggt aggctctatc
     3721 ttcaacaaga tccatctcag ccatccaagt aagagttggt tcatcaaaac cgacggcttt
     3781 gatggttttt tctgggaaat gatgttccag caaggctttc aatcccacct gacttcccaa
     3841 ggcatcaggg tctggtttca tatgacgatg aatgataatg gtgtcgtatt ctttaatttt
     3901 ttctaaaatt tgttggcaaa tctccataaa taacctcaat tctttctcat ttcattgtag
     3961 cacaagaatt tttattttta aaatgaaaaa gatgtgatat aatggagaaa gataaattga
     4021 ggaggacgat atggcattag caaaaattgt atttgccagt atgaccggta ataccgaaga
     4081 aattgcagat attgtagcag acaaattacg tgacttgggc ttggatgttg atgttgatga
     4141 atgtacaact gttgacgctt cagacttctt ggaaacagac atcgctatcg ttgcgaccta
     4201 tacttatggt gatggtgaat tgccagatga gatgatggac ttctacgaag acctagcaga
     4261 tctcaacttg aatggcaaaa tctacggagt ggtcggctca ggagatacct tctacgatga
     4321 attctgtaag gctgttgatg actttgaccg tgtctttgtg tcaacaggag cagaaaaagg
     4381 ttcagagtgt gttaaagttg atctttctgc cgaggaagaa gatattgaat gcttggaaca
     4441 attcgcagaa gaattggctg ctaaagtagg ataagcataa aagtgcgctg atgtaatcaa
     4501 tcagtgcatt tttcttatcg agagttggga ttttactagc ctaatttatg gctttttgat
     4561 acaataattc aaataaagga ggagactgta tggatttaga tattattcgt caagaaatcg
     4621 atcaaatcga cgaccaaatt gtcaaactgt tagaagaacg aatgcattta gttgaggggg
     4681 tagttgctta taagaaagct tcgggtaaac cgattttaga tactaagaga gaagaagtta
     4741 tttttgaaaa ggttaggagt cgtgtagagg acaagcgcta tcaggagact attgtagcga
     4801 ctttttcgga catactcaaa cgttcgcgtg attatcagga tcagaatatc aaatgaaaaa
     4861 agaacaattt tatccgctag gaatttttct agctgctatg ttgggcggac ttgtccgata
     4921 tctagtttcc acctggttac cagccagtcc agactttcct tggggcactc tctttgtcaa
     4981 ctatctggga attttctgct tgatttatct tgtcaagggc tatctggtct ataaggggac
     5041 tagtaagggc ttgattttag cactggggac gggtttttgc ggaggtttaa caactttttc
     5101 cagcctaatg cttgatactg tgaagctgct tgatacaggg cgttatctta gtttagtcct
     5161 gtatttgctt ttgagcatcg gtggaggcct actcttagct tattttctag ggaggaagaa
     5221 atggtaatcg tctatcttgc aattgcttgt ggtttcggag ctttagtacg ctatttattt
     5281 tcccgctaca atcaagcttc taaaatgccc ttgggaacgc tcatagccaa tcttctaggt
     5341 tgtttgttga ttggattatt ctacaatcat gtagagtcta aggaggtcta tgctattcta
     5401 gcaacaggat tttgtggaag tttgacaact ttttcgactt tgaatgacga actccaaagg
     5461 ttgctaagcg ataagaaggt attttattct tacctgattt tgacctacct aggtggtttg
     5521 gttgcgattt ttttaggaat tctgctataa atttctttac ttttttttag aaatttggta
     5581 aactgtatct tgtgtgtaat ggacgcacaa aaatacagtt tatccgctga ggaagattcc
     5641 tcaagattga caaagatagg agaataaaat gaatccatta atccaaagct tgactgaagg
     5701 tcaacttcgt acagatatcc catcattccg tcctggtgac actgttcgtg tacacgcgaa
     5761 agttgtcgaa ggtaaccgtg aacgtatcca gatttttgaa ggtgttgtta tcgcacgtaa
     5821 aggtgctgga atctcagaaa actacacagt tcgtaaaatc tctaacggtg taggtgttga
     5881 gcgtatcttc ccaatccaca ctccacgtgt tgaaaaaatc gaagttgttc gttacggtaa
     5941 agtacgtcgt gcgaaattgt actacttgcg tgctcttcaa ggtaaagcag ctcgtatcaa
     6001 agaaatccgt cgttaattcg actaaaaaac tctgcttttc agcagagttt ttatctagct
     6061 cccttagttc aatggatata acaactccct cctaaggagt agttgcaggt tcgattcctg
     6121 cagggggcat ttttagtaat gtaaagaaag acaaagaaaa ttcaaaatgt ttatttgaag
     6181 gcaattttct caagttcatt tttaaaaata atttagcatt tttaattttt ttgaccaaat
     6241 tttgaccaaa aattatattt tggtcaatga ttatagaata aaatggatca tgaaaatgtc
     6301 tctgatttat agtagtgcta aaaaggactt cctttattgg aatgtcctta tttttattat
     6361 ggaattgcca aatgacgtta aggttcagtt ctatgaactt agaaagaaag tacaaagctt
     6421 taatcagctt tcaaaaagat ttggtatgga tgtttctggc taaggtatgt gacaaggtga
     6481 attgatcgtt attgaacaga gagcgttaaa aaagggaaga atcgttacta ttccactgaa
     6541 ttaaaacaag aaataaatca acaaaagcct atataataac aaatgtatta aaaataaaaa
     6601 gatttagttc agtgtaatgc agaaccaaat cttatggata aattatttgt ctaatttttt
     6661 aggaattata tctctaaaca atatcattta acaattaaat tgttagatct agcttaaatt
     6721 tctggtttaa ttcatttatt gtgtcactat cattatattc cttaaatatt ctcatagctt
     6781 tagaacattc ttttttacct aactctattt gattagtttt tataagataa atacctttta
     6841 ggaagagtaa ataattcttt tcaaaataat atccttgcct agtaagcaaa ttttctaaat
     6901 catctataaa aaattgagca ctatctaata aattattttt taataataat tttaggttaa
     6961 ataaatacag gggaattatt ctatgcgttc cagtattagt ttttaaaaaa tatcgtgttt
     7021 ttttgattac tattctatat agtaagctaa tggttttagt attcataaaa aacactgaat
     7081 tatagaaaag ttttagttca tactccatcc aagtatctac agaaagcaga tattttatta
     7141 attcattaca tttagatgaa ttataaggaa ggtttgcaag acgattaatc tgttgttcag
     7201 caatcaattt tatgtgataa ttgcataaac ttttttcttg cttttgtttt aactctattt
     7261 tatccactaa ttcttgaagt aaaaatatat ctgaagaatt tacagcatgt tctaattctt
     7321 caaaaagaca ttcttttttg gaataataac aatgaactaa ttcttcaaat tctgaaaatg
     7381 atattccaag acggtttaac agaatataaa aatgattaat agataatttt gtaatgccat
     7441 tttcgaaacg agaaatagtt gattcactaa tttcattaca tgataaatct ttaaggcgaa
     7501 aattttttga aatacgaata tcctttaaaa ctgctccgaa attttccata atgttcctct
     7561 tccatttctg caaaaaataa aacgcttgtt ttttatttat gatatgatta tacaaaaata
     7621 aaatagaaag gacaataata tcatgaaaaa aattttattg tcaacagttg ctttattaag
     7681 cttagtagca tctctgctag caaataatcc agtttctgct caagaatcat cctctcaagc
     7741 aacttatagt aagtcaagtg gaagttggat aaaatctggt aaccgttggt ggtataagca
     7801 ttctgatggt tcttatacta caaatggatg ggaaaaaata aatggtacct ggtactattt
     7861 tgatagtgaa ggttggatga agacaggttg gattaaagaa tatgggaaat ggtattacct
     7921 agatgatagt ggtgctatga aaactggatg gtgtttggtt tctggtagct ggtattattt
     7981 aaatagtagc ggtgtaatgc aaacgggact acagactatc aatggaaaac aatattattt
     8041 agctgccggc ggtgctatgc agacaggttg gcacaatatc ggagatgata cctatttctt
     8101 tgctaatagt ggggaaaatc aaaatatcaa tcgtcgtgct ttagttcttg gtgaaacatc
     8161 aacgagagca gtacctattg cagatgttaa tgctatggaa aaggttttta gtaaccaaaa
     8221 ctttagtgaa gttgttcgtt tcccagatag aacaaaatcc gagataattg caaaaatgca
     8281 agagcttttt gaatcttcta gcgaaggcga tgtgaactat ctttacttta cttgtcatgg
     8341 aggaagagat ggaagaatct atattggtag tgatggccta gcattttctg gttgggaatt
     8401 ggcgtccgtt ttgaaacaat acaaaggtaa gtttgttgtt atgctggatt gttgtcatgc
     8461 tggaacaatt atttctaaag ataatacagg tgaaggcaat gaagaagcct ctacggaata
     8521 ttttgattta gatgaatttg tatcaggatt ttctaatatg gatggtaacg aaaaatcagg
     8581 tgagatgatt gactctaaat ttttagtatt atgctcatca agaggtgcag aatactctag
     8641 tggtggatca ttaagtttag cgactaaata ttggtcttta ggttcaggat ggaatcctct
     8701 acagaattca caagcatatt tagcagcaga ccaaaataat aatcgcagaa tcacattaaa
     8761 tgaattgtat acatactctc gtgaacaagt tttgaaacaa aattctaacc agcatattga
     8821 agtttatcct gacaacagtc aatttgtgtt atttaagaaa taagggggca ataaaatgaa
     8881 agtatcaaaa aaaattacac tatttagttt gtcttttgca ggttttgttt tattgacttt
     8941 acctcaagca ggaaaggctt ttgaacttaa agaagactgg gcatttaaag gtggcattcg
     9001 atacgagaat gggaaagtca gcaaaattaa taatggatat gaagtaaata ttaaagtgtt
     9061 agatttacct agtactagcg caatcgaatg gacagttaga ttgaatggag aaaagcaaaa
     9121 tactaacttc ttagcggagg aaagaactgt atctaaaact gaagataagg gacgtttctt
     9181 gcacttttat atcccctatg gatatcgtgg ggatattgta gtagaggcta agagtggaaa
     9241 cgaagtgaag acttggtcta ctaaggtagt tgacgatgtt tattcagatt ctgctaagag
     9301 tggctacttt attctcgatg gggaacaaat cttagaaagt tcatgggatt ccgtaaatga
     9361 gtcttatatt gcaacgcttc caactgtaac atcaggaaaa actgttgttg cttggcgtga
     9421 agaaggaact cttaatttaa ttaaaccagg aagaattgtt cggcaatata atagcagtgg
     9481 atcatatgta gaactttctc caatctttga aactgctagt tggctaaaat caaaccaaaa
     9541 ctggtactat caaaaacaag gtcaattagt tcaaaattct tggatcaagg atcagggaag
     9601 ctggtatgcc tttaagtcat caggagccat gatttcagct gattggttgt atgataatgg
     9661 ttcttggtat tacctaaagg actcaggttc tatggtaaca ggatggctta aaaatggagg
     9721 ctcttggtat tacctaaaca agtcaggttc aatggctaca ggttggatta aagatagtgg
     9781 aacttggtat tatctaaaga attcaggctc tatggcgaca ggctgggtga aagatagtgg
     9841 ctcttggtat tatctaaaga actcaggttc aatggcaaca ggttgggtca aagataatgg
     9901 taagtggtac tatctcgcat catctggtaa tatgcttcgc aatacacgca caccagatgg
     9961 ctattatgta gatggcagtg gcgcttggaa ataaattttt aaaagagaaa atctactgag
    10021 aaggtagatt ttctttttag ttaatgaata tagaataaag tagatcagga ctggtctatt
    10081 ttattttgta actattaatg aatagtctta atgatgaagt tattttctga agatatttaa
    10141 ttgtgttgag atttgataaa actatagtgg attgaaataa gatataaaca aagagattat
    10201 ggaagtcaaa ttaatttcta aaaacgtttt aaaatcctta gcgtactatt ttagattcaa
    10261 tttaatatag tttaaaaata agaaaattac gtaccttatt cttggtgata aaaatgcgaa
    10321 tttagataaa tatatttgat ttgtagaagg tgctcataat ccatatttta aaatttatac
    10381 tattatactg aaatttaatt gtagtttatt gaatgctatg tatttttatt tcttaatgct
    10441 ataatataaa gtatatagag ttattttaga ggtgcagatt tggccaataa taggaaaact
    10501 gagacattag gtgtttcata tctttcaaca tttatagata agcatgagtt acttcaatct
    10561 tattttgaaa gtaatgataa aactccagta tgggatgggg aaattcatgt tcttaaatca
    10621 actagtgaga agaaggaaga aatattcggt aaagtgcctg ttcaaataaa agccactaga
    10681 caaaaaatga atgcacttaa atcattttca ttaaatatta gtgatttaga attatataaa
    10741 tcaaatggtg tactgacccc aaaaagttag acaaataatt tattcaaagg atttagttct
    10801 gtactgcaca ggactaagtc cttttag
//
LOCUS       DAVDHZ010000059        10229 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000059 DAVDHZ010000000
VERSION     DAVDHZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.060"
                     /strain="36"
                     /db_xref="taxon:1313"
     misc_binding    complement(246..463)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(546..3242)
                     /gene="ppc"
                     /locus_tag="VUR46_001988"
     CDS             complement(546..3242)
                     /gene="ppc"
                     /locus_tag="VUR46_001988"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET5457343.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMNQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(3262..4491)
                     /locus_tag="VUR46_001989"
     CDS             complement(3262..4491)
                     /locus_tag="VUR46_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET5457344.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(4647..4873)
                     /locus_tag="VUR46_001990"
                     /pseudo
     CDS             complement(4647..4873)
                     /locus_tag="VUR46_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(5278..6174)
                     /locus_tag="VUR46_001991"
     CDS             complement(5278..6174)
                     /locus_tag="VUR46_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET5457345.1"
                     /translation="MTKISFEIQQQIIQCFGLCFHYKDTVVSFMQTSGVLNDLILKWK
                     SEPKFVWAKNVINELNKTENGRSIIRRIATEFYKMKNISDEVQDRDRGLDALRKLKRL
                     IGDTQQNKVNETLNNSYHRSRQEMKIQLKQQLLQKIEELKTEYYSLFSSDNPQERGYR
                     LEKIVANLFRINDIDYHDSYRNRTNTQQLDGYFRFEGFDYLVEMKWEKNPVNSSKIAS
                     LKQKVDTKLTSTRGLFLSINGFRDEVIQDFSNKDAKILFMDGQELAYILENRISLYEA
                     LKVKIIGASKTGNPNVSIINQE"
     gene            complement(6225..9185)
                     /locus_tag="VUR46_001992"
                     /pseudo
     CDS             complement(6225..9185)
                     /locus_tag="VUR46_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            complement(9182..9991)
                     /locus_tag="VUR46_001993"
     CDS             complement(9182..9991)
                     /locus_tag="VUR46_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
                     /protein_id="HET5457346.1"
                     /translation="MEKMHSYIKYLIHEDPIITDEGKQVEILHLDIQDDPEIFEDWAN
                     QFRRNYCSDDELAEMIGFMNISPKEYLKNFKLPSDSGIGLSTMSGDFGEILVSDYLQN
                     IEEYVVPRTRYDSRVNKDTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSQA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQENVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKKHRDFQKLRLLVIHSDELMKFIRELYSKASEV"
     gene            complement(9975..>10229)
                     /locus_tag="VUR46_001994"
     CDS             complement(9975..>10229)
                     /locus_tag="VUR46_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PezT"
                     /protein_id="HET5457347.1"
                     /translation="EHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGEWNTVEKEMLKIGQERLWDMSKSNGKDA"
BASE COUNT         3246 a         1986 c         1474 g         3523 t
ORIGIN      
        1 taagttatat ctgcacctct ccttgaaaat ctactgaaaa cagtgtgaaa acgtcgtttt
       61 cagcagggct tctttagtgc accctttttt tgaaatagtt ttcaaacttt gagcgggggg
      121 tcgcttgaca ttttaccact agactttgta tttcctttaa catatttcac ttatctaaac
      181 aagcgacgcc atcgttttct ttccatacta atctccatca aaaaaaatcc tcacacaagt
      241 ttttgtgtga ggacgtcgat gcgcggtacc acctcaatta tagggaattt ccctatcgct
      301 cagtctcgca ataacgagat gcactgtaag gtgtgctcac cgaattttta taatttcaaa
      361 ttctaaatag cattcagccc aattttcatc atcgccactt atctgttttc agctaccaca
      421 gactctctaa aaagtttgta tgattacttt tctgaatggt taaattatat catttttaaa
      481 ctacttgtca atagtctatt agaatttttt tgatattcac ttttagcatt cactcttgaa
      541 aattatcaac ctgaattacg caatcctgtc gcaattccgt tgatggtgat atgaatcaat
      601 cgttcttgat cactggacaa ttctccacga cgttggcgtt taatcaactc taactgaata
      661 tagttgagaa tattaaagta aggcatacgg taatccaaac tagcttttag atatggattg
      721 tcagctaaga gttcgtcatg tccttcaata gccaagataa cgttcttagt aacttgccat
      781 tcatttaaaa tagtctcata gatggcctta acttgctcgt cttcacaaag tttagcatat
      841 tcaaaagcaa tattcatatt tgattttgac aaaaccatat caacatttga aagaagcgat
      901 tggaagaaag gccaattttg gtacatatct cgtaagatag caatattctc tggattttta
      961 ttgataaatt ccttgaagct tgaaccaacc ccgtaccatc cagggaacat aacacgactc
     1021 tgtgaccatg agaataccca agggatggca cgcaaaccac cgatttcagt aatagtctta
     1081 cgagcggctg gacgagaacc aatattaaaa cttgaaatag ccttgattgg acttgactcg
     1141 aagaaataat catagaaatg ctcattacca aagaccaaat cacggtagat atcgtaacta
     1201 cggtccacta cttgattcat aatagcttca taacgatttg gggtattggt atcgctcttc
     1261 ttctgagtaa tcatacggtt aatagctgcc gatactagca tttcaaggtt atagtaagcg
     1321 gcgtctttgt taccgtattt attcccaatt acttcaccct gctccgtcaa gcggatacga
     1381 tccttgatag acttgagcgg ttgagatgta atggcttcat aggttggccc accaccacga
     1441 ccgacagtac caccacgacc atggaagaag gtaaccttaa cgccaaattc atctccaata
     1501 gcagtcaatt gttgttgagc cttgtagaga gtccaacatg aagacaagta accgccatct
     1561 ttattactgt cagagtagcc aagcatgatt tcttggtagt tatttcgtga gtcaatccat
     1621 tttttggcaa ggctaagaga aagatatttt ctcattgttt cctctgaatg atccaagtct
     1681 tcaattgttt caaaaagggg aacaatctga acacgagccc tttccgtatc caccagtcct
     1741 acttctttta acagaatagc taattctagc atatcagaaa gactggttgc atgtgaaatg
     1801 atggtctgac ggatgacatc atctcccaac ttatctttca aaacacgagc cgtcttaaaa
     1861 atagctagtt cttttgctaa taattctgat ttttctgcgt gagtcgcaga aagaattcga
     1921 ggatcttctt ctaattcttt caagagaagg tcacactttt cttcttcgct caactcgcta
     1981 taacgagaat gaattcctgc tgatttcaag agttctgcca cacaggcttc atagacgcta
     2041 gagtcttgtc gcatatcaat tgatgctagg taaaaaccaa atatctctac tgcctgcaat
     2101 aattccacaa aatcacctga aatcaaggac tcgcccttat tttctagtag agaatctcga
     2161 atggcaatca aatccttgta gaaatcattg gcggtttcat aacgagtccc aacttcttca
     2221 tcctcaatca gataggtttt agttgcctga atttttgatt gaatatcaaa caaggcacga
     2281 cggtaaagct ctttttcgcg gtaaatcgag ttatccttgg attgacgagc catttctctg
     2341 acttgcttgc tgacgttgac aatgctagtt gaaagagaaa attcacgata aagttggtaa
     2401 atctttttat catagtagtt catgatgact tcacattgag tgagtgcaga ctgcttcaag
     2461 gtctctgctg taacaaatgg atttccatca cggtcaccac ctatccacat acccatggtg
     2521 attggtttag cttgttttaa attcagacca tgcgcttgcg ctaagcgctt atactccgtc
     2581 gtcaaatgag gtacagcttt caaaaaggag ctgttataat attccatagc attcgtgatt
     2641 tcgttagtca cttttaattt tttctcacga atcatgtctg tctgcatgat aatttcgatg
     2701 taacgacgca aatcattgta ccatttatct ttattgatca accccaactt aacatcacgg
     2761 tatttacgca aaagactatg aatatgattt gttaaatcca acatactttt gcgttgcact
     2821 tgtgttggat gggctgtcaa aacagggaca acattcaagt gttctaggat ctcaacggca
     2881 ttttcctttt ctgctaccaa tttaatcgtt gtagataatt tacctaaata gtcctgatca
     2941 atattatttt gatgattgat ttcataagct aaatccacat cctctgaaat attaatcaaa
     3001 agaggtaaga tagagaaata gcgtgaaata tagaccattt catcatttga taagctagtc
     3061 actagacggt ttagaccttg ataatcttcc tgcgttgata attctttcaa ctgtattatt
     3121 ttttcaaagg tctctggggc aagcatattt ttagtaatat cttccagtaa ttctgttaga
     3181 atcaagactt cttcttgcac aacactttta ttactataat tttctaattt ttgaagagac
     3241 ataaactatc ctttctttat cctacttcaa cagaaggttc attggttgat tttccaattc
     3301 tcggtacaac ttagcgcgtt tttcactggc atcaatattt aagacaaagg ctactgccac
     3361 tgataagact agaagactat ttccaccctg ggataagaag gggaaagtca ctcctgtaga
     3421 tggaatcaag cccgaaatcc ctccgatatt gacaaatacc tgaaccaaca tcatccctcc
     3481 gacaccgagc gcaaccatgg cattaaaagg attctctgct cggatgccga ccaagataat
     3541 ccgcaaaatc atgaaaaaca agagagctaa aataagactg gcaccaacaa agccaaattc
     3601 ttcaatcacg atagaaaaaa caaagtctgt atgagcttct ggcaaataac ctcgtttttc
     3661 aatcgagttc ccaagaccta gaccaaacca accgccattg accatggcaa aataagaatt
     3721 agctaactgg tgacccgcat cagcacgatc ggcaaaagga ttaaaaaagg cactaaagcg
     3781 cttggctaca tagccaaata ctggaatttt tgaaaaggtc tcaacaccga ttaggctgat
     3841 agtggtcaag acaaagacag aagcggcaga tacgagcgcc agaatggttg aaaaccagcg
     3901 ataagcgatt ccactaactg tatacataat caaggaaacc aagactaaaa tagtcgcatt
     3961 tcctaaatca gggaaaatgc ccaaacttcc aatcagaact aggagaacga atcgccaatc
     4021 attaaaagca cggggaagcc attgattttg agtcaaaact tgaaaatcat aagtagctat
     4081 ttcttcttgc tgtttggaga atcggtgagc taaataccaa ataataatga tttttaagta
     4141 ctcagctggc tgaatagtta ctcctgcaac cgaaatccaa ccgtatgccc cgtttacgga
     4201 aataccaata aaacgagcca agaacaataa aagcatttct attaatataa ctaaaatgat
     4261 tagtcgctca tttctcaaaa aatctagtct caatttataa attaaggcaa tcagtatcaa
     4321 actaacaatc caaaagattc cttggtttcg aaccaactgc aaggcgctct tgccttcttc
     4381 aattaaaata gcactagtgg tcgaatagac cacaatcaag cccaaaatag ataaaagcaa
     4441 gtagggaatc aagatggaat aatttaataa gtgcctctta ctaatcttca tagcatcacc
     4501 actctactag gatacagaca aatctgttcc aaattccgtt ttattttcta gttttgattg
     4561 ctattatacc attttttcag aaagaaaaaa actcttacct tacaatcctt cgaattttac
     4621 tgtttttaca gaattaaggc agaatttgaa atcgtaaaac cattttgaac aagagttact
     4681 tcaacccatt ggctccgact aattaagttg ctttcgtgaa tgctaaaatc agccgcaatt
     4741 tgttcataag tgcgctattc tcgcatgtat tgaatagtta ccataaggag atcgtctagg
     4801 cttaatttgg gttttcgtcc accttttgcg cgtttacgtt gcgttgataa gctgttttta
     4861 acacagctaa catctcgtgc gctgaacacc tacaaggctc ttgaaacggc tatcgcttaa
     4921 ttgtttactt gcttcatcat ccatagtttt attgtattgt attgtatttt tgtttcgcag
     4981 gaagtctatt attcctttcg ttccaaggtt tttacgcttt tagcaacact acacactcca
     5041 cgtgatgcgt ctgtggaact caaaaggttc ggggaacctt ttgaggatta attgcgtttc
     5101 tctaacaaac tcacacattc aacgtggcat gactgatgaa gtcatcataa aaatttcact
     5161 tgctgctctt ttacgttggc agcctgaacg gtcagaagta tcattgtata tcatttgtat
     5221 catggcatat aaagtatcgc tctattttat tgatggtttt aatatctctc ggaaaagtta
     5281 ttcttgatta attatagaaa catttggatt gccagtttta gaagcaccaa ttatcttaac
     5341 ttttaaagct tcgtacaaac taattctatt ttctagaata taagctaatt cttgtccatc
     5401 cataaataaa attttagcat ctttattaga aaaatcttgt attacttcat ctctaaaacc
     5461 atttattgaa agaaacagtc cccgagtcga agttagtttt gtatcaactt tttgttttaa
     5521 agaagctatt ttcgaagaat ttactggatt tttttcccat ttcatttcaa ctaaataatc
     5581 aaaaccttca aacctaaaat agccatctaa ctgttgagta tttgttctat ttctatacga
     5641 atcatggtaa tcaatatcat taattctgaa taaattagca acaatttttt ctaaacgata
     5701 tcctctttct tgaggattat cacttgaaaa tagcgaataa tactccgtct ttagttcttc
     5761 aattttttga aggagttgtt gcttgagttg tattttcatt tcctgtcttg aacgatgata
     5821 agaattatta agtgtttcgt taaccttatt ctgttgagta tcacctatca gtcgctttaa
     5881 ttttcttaac gcatctaatc ctctatctct atcttgaact tcatcagaaa tatttttcat
     5941 cttataaaat tcagttgcta ttcgtctaat tatcgatctt ccattttctg ttttattaag
     6001 ttcatttata acatttttcg cccaaacaaa cttcggttcc gatttccatt ttaatattaa
     6061 atcatttaga actcccgaag tttgcataaa tgaaacgaca gtatctttat agtgaaaaca
     6121 taatccaaaa cattgaataa tttgttgttg gatttcaaaa gatattttag tcattttttc
     6181 tcctttctat caacaatatt acatttcatt aattatctgt gtataataac ttggaccaca
     6241 attctatctg aaaaacctaa ttcatagata ttgatttctt tttccagagg tagcccatat
     6301 ttcagcctct ttattaacat agtcaatacg tccaattcct ctccaactag tttttcaaga
     6361 atattattaa tcgcatttaa aaccattgat gtttcatacc ctaatccatt atcacaaata
     6421 gagattatgt cagacatatc aattggtttt gacttacctc ttttctcaat actaattgat
     6481 ttttcagtac aactttccaa tatttgaaaa taagaaatcc ccttaatcca gagttgagaa
     6541 atataattta gattttctat acttagtttt ctcatctctt tgttatttga aaaatctatt
     6601 attttcttgg ttaaaacacc taataactct tcttccttct cacaagaaat gatagatgtt
     6661 ttattttcct gaacccattc ttttaataac tcagattgat ataatccaat tgagtttttt
     6721 gcaattattt cagtttctac tgaactggta attattttag attttatcaa gataaataat
     6781 tcttttattt tttctttttc ctcttcatta ttacctaaga aatatccaaa tgtattttca
     6841 gctaaactat cagtctccaa ttcagtagca tacatagaag caatataatt ttcaattgca
     6901 attagggtat tatcaatctg gtctatctta gaattaaaat ccttaaaata aagactgttc
     6961 tttcttttta attttgataa aatattattt atttttgttc tgtagtctac agaactgtca
     7021 aatctctctt taatcaaatt ccaaaaatca aattttatag gagcgaatcg ataatcagtt
     7081 ggaactactg atttaaactg tataatactg agaatattac tttgacaacc ctctgtatta
     7141 ataggattta acaatgcttt atagttttgt tttttccact tattttttgg tgatttataa
     7201 atattgggct ctgttaaaat tattgttcct tctgtatatt ttccagccct tcctgctcta
     7261 cctatcaaat tctgaaaatc acgaactttt attgcatctc ctgcttgata cacacttgag
     7321 ataatcaagt atttaatagg taagtttata ccttgtgcta aggttgaagt acatactaca
     7381 ttatttattt tactttttga aaaagcatac tctatagcaa tgcgtatccc cataggtata
     7441 cctgaatgat gtgaaaaaac tcctagctga ctacatgtat attcaacact atcatatcct
     7501 aaattttgac caattaaatt tcctattttt tcaacttcag acctatctga gttttttaag
     7561 aaatcagtta gatcataatt tctattattt aagtctataa atcttcgtaa aataacattg
     7621 accgtgtctt ttcttccaca aaaaattcct actccaccat tattaattag attaatccca
     7681 taataaatac ttatatcatt ttcgtttgtc agttctggaa aaactttttg tttgcgttct
     7741 tttccaagct gctctaattc actaacacta acagtacgtg gaacaaaaaa ttcttcttca
     7801 aatgtaatag gatctatgaa atataattgc tcattactcc cgtttaaatc actaaacgca
     7861 actcttttct ctgttgtttt aatcgaatta ttagaaacaa ttactccatc ttcgttaaac
     7921 caccgattta tagcttcact atttggtatt acagcagata ttaaaatctt ctgtattcct
     7981 tttgggaaaa tttgtttaac cgttgacaac agtaattcaa aatttgttcc acgacttgga
     8041 tcatcaaaaa gatgtgcttc atcaaatata caaagtccta tttcatcaat aaaactttga
     8101 tgatttctca ataaaaacaa caattttcct ggagtaagta taaaaactct ttttttacca
     8161 tcattaaaaa ttgagaaatc ctgtggaatc tccggtaaat caaaaacttc actaacaatc
     8221 acattattct catcaacgaa atgtgcatta atatcacgat atatttctct acataatgct
     8281 ctaaaaggtg caacaatcaa tgcattatca attctatttg aataaaatgc tgatcttaag
     8341 gttagattga ttgaggctgt tttacccgaa cttgttggca tctgaacgat tccagattta
     8401 cctgaaaaaa ttgcttgctt ccctaattcg atttgagatg gccaaagctc ctttatactt
     8461 cctgttgatt gtatataatc ctgccataaa gaaaaatcta atcctgaaaa ttcaggtaat
     8521 aatttcgttg atgaactatc tattttttta catacaactg ctaagagaca atttacaatg
     8581 attacagaaa aatcgcttcc attcctatat actttatctt gtaaatctct ataaatatct
     8641 atagaaaact cagtttttga taaaatataa tttctatatg attccaccag agtatttaac
     8701 tcactagagt atttaccttc tattggcgta tgattcaaaa agagtttatc tgtaataaca
     8761 ttaataaata cttttacaag agttatactc tcttctaata actgcatatc atccgatatg
     8821 tagttaacca taactctcga actaccatta taatcgccta gataataagc tgtggtacct
     8881 agtattgcaa tatagtcttg atattcagct gaatttccta atcctgacac cagcaatgca
     8941 tcaaaatatt cagcaacatt gtgtaattga ttttttaatt gtgaatcaaa actcttatga
     9001 ttgatataat cttcaaaata cttcctagca gtatctgcag caattgctaa tgccccaaga
     9061 aacgattttt gagcatcctc agaaattgga atatgacttt ctaaaggaat ttcaaattca
     9121 atcatctttg cctttgaacg cactaatttt gaaaaatata atgacttttt cccaaattct
     9181 atcatacctc actcgctttc gaataaagtt ctctaataaa tttcattaat tcatcagaat
     9241 gaatgaccaa tagtcgtaat ttctgaaaat ctctgtgttt ttttgaaact actgtcttga
     9301 taacatcaat atcatatgat tgattggagt agactgcaac agctccatag attacattaa
     9361 atggtttatc cgttatgttt aaaaatcttt ctactacatt ttcttgatca ctattagatt
     9421 tctttaacct taaatagcta gctacaattg aggttgaaaa tcgttcaaaa tctttatcag
     9481 aatgattaat agcttcttga agcttatttt tcgcttgaga gctactagaa tcagatgccg
     9541 atgattttac ttcaataact acaacctcat cattcgatac attcgaagaa tcttgcttat
     9601 atcctagaac atcacttcct tgagttgaag tatctttatt gactctacta tcataacgag
     9661 tcctaggaac cacatattct tcaatatttt gaagataatc agatactaat atttctccaa
     9721 aatcacctga catcgttgaa aggccaatac cactatccga gggtaattta aaatttttaa
     9781 gatactcttt aggggagata ttcataaaac ctatcatttc agcaagttca tcatcagaac
     9841 aataatttct tctgaattgg tttgcccaat cttcaaaaat ttctgggtca tcttgaatgt
     9901 ctaagtgaag aatctcaacc tgcttacctt catcagtaat aataggatct tcatgaatta
     9961 aatactttat ataactatgc atcttttcca ttacttttac tcatatccca caaccgttcc
    10021 tgccctatct tcaacatctc tttttcaacc gtgttccatt ctccaaatag taagtcatga
    10081 agaactgttg ctgctgaagt tgtattttct tttgaatcat atacacaact tctatctcgt
    10141 tgataaattt gaatgctttc aaagatagcc agttcttcca attgtcgtgt attatcaact
    10201 agatgattta caatgaaatc atgatgttc
//
LOCUS       DAVDHZ010000060        10105 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000060 DAVDHZ010000000
VERSION     DAVDHZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10105
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.061"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(27..2234)
                     /gene="nrdD"
                     /locus_tag="VUR46_001995"
     CDS             complement(27..2234)
                     /gene="nrdD"
                     /locus_tag="VUR46_001995"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET5457348.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLDDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(2354..3892)
                     /locus_tag="VUR46_001996"
     CDS             complement(2354..3892)
                     /locus_tag="VUR46_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET5457349.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSFLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(3929..4072)
                     /locus_tag="VUR46_001997"
     CDS             complement(3929..4072)
                     /locus_tag="VUR46_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457350.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(4150..5682)
                     /gene="cls"
                     /locus_tag="VUR46_001998"
     CDS             complement(4150..5682)
                     /gene="cls"
                     /locus_tag="VUR46_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET5457351.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(5828..6373)
                     /locus_tag="VUR46_001999"
     CDS             complement(5828..6373)
                     /locus_tag="VUR46_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET5457352.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKSIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            complement(6370..7620)
                     /locus_tag="VUR46_002000"
     CDS             complement(6370..7620)
                     /locus_tag="VUR46_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET5457353.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(7927..8232)
                     /locus_tag="VUR46_002001"
     CDS             complement(7927..8232)
                     /locus_tag="VUR46_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET5457354.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(8248..8667)
                     /gene="ruvX"
                     /locus_tag="VUR46_002002"
     CDS             complement(8248..8667)
                     /gene="ruvX"
                     /locus_tag="VUR46_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET5457355.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(8671..8937)
                     /locus_tag="VUR46_002003"
     CDS             complement(8671..8937)
                     /locus_tag="VUR46_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET5457356.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(9024..9593)
                     /locus_tag="VUR46_002004"
     CDS             complement(9024..9593)
                     /locus_tag="VUR46_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5457357.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGSATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            complement(9659..10057)
                     /gene="spx"
                     /locus_tag="VUR46_002005"
     CDS             complement(9659..10057)
                     /gene="spx"
                     /locus_tag="VUR46_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET5457358.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         2915 a         2250 c         1827 g         3113 t
ORIGIN      
        1 ttgatatttt cccatttcat ttctttctaa tttgttactt gatgcccagc tattttaatc
       61 gttgaaccat tcatatgttt gacacgcgca gcgatttcct tgtgacgccc gttaaccatt
      121 ggtctcgctt gaggattgcc aagatagcca caagtccgtt taacaacgtc tactgtttta
      181 ggatcgctat tgccacagtt tggacaagca aaccctctct cagttggttc aaaatcccct
      241 tcaaagtcac acttgtagca acggtcaatc ggagtattgg tgcctagata gcctacacgg
      301 tcataagcat aatcccagac agcttccaag gcctttggat tttgctgaag gactggatac
      361 tcacaataat ggatgaaacc acctgacgca cctgcttccg gatagacttt ctcaaagtct
      421 aatttttcaa acggtgttgg atttttacga acatcgtagt ggaaagaatt ggtgtagtat
      481 tccttgtctg tgatatcagg aatagagcca aacttgtcta tatctagtcg gcagaaacgg
      541 tctgtcagac tttcggatgg tgttgagtag atagagaaat ggtagccata ttggtctgac
      601 cactcttcta cacggcgttt catatcgtga atgatgtcta gcgtgaattc cttagcatct
      661 ggattacttt cccagctgtt accaaagaaa actgtcgcta cttcatacaa gccgatatag
      721 cccagcgaaa cggtcgcacg acgattctta aagagctggt caacactttc ttctttacct
      781 agacgatggc caaaagcacc gtactgataa agaataggag cattcgctgg tgtcgcctct
      841 ttagtgcgtt cgacacggta aacaagagca tcttctgcga tattcattcg ctcgttgaag
      901 atttcccaga acttattcat atcaccttca gactcaagag caatacgagg cagattaacc
      961 gtcacaacac ccagattcat gcgacctgaa ttgacttcta caccattttc atccttccac
     1021 ccttgaagga aagaacggca gcccataggc accttgaaag aacctgtcaa atcaacaatc
     1081 ttatcataag acaagacgtc tggatacatc cgcttggttg cacactctag agccaactgc
     1141 ttgatgtcat agttgggagt tccttcctct aagttgaggc ctcttttaag cgtaaagata
     1201 agtttaggaa agatagccgt acggtgttct gaaccaagac ccttgatgcg aatgtttaaa
     1261 atagcttttt gaatttctcg ttcaaaacga ctggttccca gaccaaaacc taacgaagta
     1321 aaaggtgttt gtccatttga agtgaagaga gtattgattt catactcaag agattgcatg
     1381 gcatcgtaga tgtccttttg cgctttcttc caagcgtaat cttcctgttt ttcaggcaat
     1441 acccactctt ctgcatcttt gagatgtttt tgataattct tctctgcata aggcgccaaa
     1501 atttcatcga tacggtcagc tgaacagcca ccgtactggc tagaagcaac gttggcaatg
     1561 atttgagaaa tctgtgctgt cgcagtctgg atagacttgg gactctctac ctctgcattt
     1621 ccaatcttaa aaccattttc caacataccc ttaaaatcaa tcaaacagca gttggtcata
     1681 ggggtatagg gactgtagtc caaatcgtga tagtggatat cccccttttg gtgggcattg
     1741 gctacgtgct taggaagcat ttgcagtccg attgatttcc caacaatccc tgctgtcaaa
     1801 tcacgctgag tgttaaagac atcactgtct ttattagcgt tttcattgac aactgtctgg
     1861 tctttgttga gaagtttatg aatactaaag ttgatatccg tcgcttttga gcgctcaaaa
     1921 tccctctgtg tccgataagt aatatactcc tcagccagcg catattcttt ggcttcaagg
     1981 agttcatgtt ctacgatatt ttgaatttcg taaatcttaa ttccctgtgg aaagcgacta
     2041 tgaatttctg taataattcg ctcagtcaga tcatcgaggc gtttttcaac caggggtgtc
     2101 acatccataa ccttgtcagc cgccttgtgg agagccttgt caatcttgtc cacatcaaat
     2161 acaacacgtc tcccatctcg tttctcgacg aagagagttg gcaaaattgt aattttttct
     2221 tctagtgcaa tcatatgcat gctcttttct aaaatgttct ttctaaaaag tattatacca
     2281 ctctaaaaag aaaaatcaat atcttgtgtt aaaaatccta aaatttttaa aaatacacaa
     2341 gatattgatt tggttattta attttataga ctttaaactc tgagtaatca gtctttactt
     2401 gttggtaatt ttcttttaag agtgtttcca cttcagacca gactaccacc ttatcattta
     2461 ccacaatcac cttaggttgt ttttctttca agtcattaag taacttatta cgattttcct
     2521 cagttgctgt atagtgcaac ggggacaaaa tcgccgatgg cgacaagcgc tcactcttac
     2581 gataaagagt cgcagtatca tcccatgcat agatagcatc ttccgtattt gtctcctctt
     2641 ttaccaaatc agcaagacga ttacgttctt gataaggtac tggataaagg acaaacttca
     2701 tcaaaaaagg aacagacaaa agatagacaa acccaaaaac tagcagatat agatttcctt
     2761 tgaagaaacg actccatagg ctaactggcg tttctcttcg gcttcttcta gcactacgcc
     2821 ccctctgttg actcttaata ttggttacca ataaaagtag gaaaacaggg aagacgacca
     2881 tcaaataaga agcgtgcaga ggctcttgtg aaaagaaaag taaaatcaaa cctaaaatta
     2941 ccacaagact tgcaggaacc gaaatgacgt atagtttaaa gggtttggat tgaaagagac
     3001 ctaaaaagat acaaaccaca aatcccaaac caagggacaa caagccataa aaaaacatat
     3061 tctctaaaat tttagaagta aaatcaaagc gaatactgtc aataggataa cgaataccac
     3121 taatcgcatc cccaaaactt cctgttgcag cactatagta ggcagttgga taaaagacaa
     3181 gtgaaaaacc taaagccact gcaagaaact gataaaaccc atgcgcaaag cgtctatgcc
     3241 caaggttaaa gaccaacaag cctaaactca ctacagcaat aaacaggaac gatgataagg
     3301 gagcaaagaa aaatccgcct gccaaagcta gcccaatccg tacaaatccc ttatcatggc
     3361 ttggattgct taggtaagcc gcaactaaac taaaggctgc gaataagaaa ggaagcgcta
     3421 aaagagtcgc atagcctcca ccaaaagcaa gacctgtaac tagcatgtaa aaaatagtca
     3481 ccagatgtcc agcttggtct ccttgctctg tcaaggtgtc cgctgatcta aaaaggaaaa
     3541 atcctcctgc taccaaggct aaccactcaa agatggcaaa gaaaaatccg ccctgactca
     3601 cgtaagtcag caaataataa agcaaacctt gacttccata atagtcgctg taaatcttcc
     3661 ctgtctgatg aagcgcccaa cctgcataaa aatcctgcac ttcttgtgca ctcattaagt
     3721 cgagtaatag cggtactcct agagttatcc ccgttacaag cgtactccat agtaaaattt
     3781 tcaccaaagg aagacgactt gattcacgat gatgcgattc ttgttcgatt tggtattcta
     3841 gaggttcacg attctcctta tgaacttctt ctactctacc atacacactc atatcgtttc
     3901 tcctgttcaa tttatctgtc ttagtatatc aaaaagtcct aggattgtca gcttgcgatg
     3961 gctgtttgag tgattttttg catagtttca caaaggtttc aatttcccga aagcggtgta
     4021 aatgtgtctg tttgaactca atcatatcat tcacttcttc cttagttagc atgaattccc
     4081 ctcctctttc tttctattcg taaaagacaa gaaaaatagg tctggtttgt atcctaagtt
     4141 ctagatttct tataagatag gggcgaatag ctgggcgatt tcttttacaa gcttttgata
     4201 ccagctcgtt ttgatagaat gaggatagac ttcctgagaa tctgcaaata tatttcgaaa
     4261 atctcgggcg atttccctta tagaaggagt tttatagagt aagactgcat tttcataatg
     4321 gtgtaccaag ctccggtagt cgagattgat tgtccccacc accgcaaaat cttcgtctac
     4381 caacatctgc ttactatgaa taaaacctgg actatactca taaatccgaa caccagcaga
     4441 aagaaggtcg ggataagctc ctctcgtgac taactgaatg aacttcttat ctggtatgta
     4501 aggggtgata attcgaacat cgacccctct catagctgca tttttgattg tctctgttaa
     4561 atcataatct ataatcaaat aaggtgtcgt aatatagacc gattccgttg cttgattgat
     4621 taaactctga taaacttttt tccctacctg cgctcgaaaa attggcttgg gtccacttcc
     4681 gtatggaatg gttaaaccgt cactcgggat agaatgattt tctaaatgat attgatcaaa
     4741 atcactaatt tctcctcgat taatgtacca agtggtcaaa aataagcgtg tcagggcttt
     4801 tactgctagt ccgtctaagc gaattccact atccttccaa taaccaaatc tctcgacgtg
     4861 gttaatgtac tcatctgcca gattgacccc accagtatag gctatctgac catcaacaat
     4921 caatattttt ctatgatctc tgttattata agccactgtc aaacgaggaa taactttatt
     4981 gaatttatgg gcctcgatgc ccagctgacg aagtcgatgt gcataatctc ctgttaaagt
     5041 agccatacag ccgatatcat catagagcat cttaacctct acaccctgag ctaccttttg
     5101 ctctagtata tctagtatgc gattccacat caaaccttct tctataatgt aatattccaa
     5161 gaaaataaat ttctcagcct ttttaagatc ttctaccatc tttttccaca tagcttctcc
     5221 gttaggaaaa aatgtagagg cagtttgatc atagatgtca gcattggtat ccatactcaa
     5281 taaggacttg atgactccat aagctgcctt gtcactttct tttaatttct cttttagtag
     5341 ctggctattt gcttcttgga aatgcatgga gcctagcttc ttcagttgtt tgatttcttt
     5401 ttttgacaat cgcctttcac caaacatcag atagagcaag gggccaaata ctggcacaaa
     5461 ggctactaac aaccaggtta ccttattctc aggagtcgta ttacggttga ctatcgaaat
     5521 gattgtaatg atactcagta gaatgaggac agtaatccat aaaatgggag ccatgcgtcc
     5581 taaataaaga aagagaccaa aaaccagaca aagttcaagt agcataatcg aaagactaaa
     5641 gccatacttg gacatcaata attgaaattt cctatatttc atatcccctc cttgatagtt
     5701 tgaatgctaa aaacaagtaa ttgatactag tataacgcag gtattcggta gaaggcaagt
     5761 atttatgatt attttctagg taaaagtaaa aaggctgaaa aatccagccc tttctacttg
     5821 catagtctta tttagttaaa acgatttggt ccgatgggtc tctatccata tcatctacga
     5881 cgatttgatt accgtttaca gtgtaaattt tgacatcatc gccaataatc atgcgttgat
     5941 ttgctgaatc aaatgtaacc tgtttgactt tctgatcccc gtcagattcg agctcagtcc
     6001 atgtaccagt cgttccagtt accactaaag tgatacggtc tccgtcatcc tgaccagtat
     6061 aagtcccatc aatatcggtc ggctgagcaa caggttggtt ttgtactgga gccgcttgat
     6121 tttggttacc ccctgcattt gcagtattgg tattctgttg agcaggctgt tggacctgct
     6181 gctgagcaac aggctgttga acctgttgag ctctttgtga acaagctact aagagactaa
     6241 aacttgctag agaagcaaga gaaagtgtga atctttttaa tttcatgatg gatttccttt
     6301 ctgctaccaa tttagagaaa ttttctctaa ccagcaattc ccctagtata acaagttcaa
     6361 aaaagggggt caatttatct gctcacggtc cagcaggtag ccccgtactt ctgagataaa
     6421 atagagagac cctgttacga acagcaagtc ttgagcgtct gccctttctt cgaaactgct
     6481 gataaattct cggtaagagg gaattacatg gtaacctgtt acatctgtct cgtccaaaga
     6541 cccttgatag tcaaagccag tcatcttgag ttccacttga ggtaaatttt cagtcagata
     6601 acccaacatc ccttgataat ccttacgttt caaggatcca aagaggattt gaggtcgata
     6661 accttcctgc tctttttctt tgataaactc aaccaagcga gtcaaggcag ggaggttatg
     6721 agcaccatcc aaataaatct gtgggcgaat acgctccaag cgaccagccc aatgggtctg
     6781 ttccaaggcc tttcttacag cctgttcatc aacagcttcc tttccttctc ccataaaaag
     6841 aagaaaagtt tgcaacgcca aggctgcatt ctcctgctga tagactcctt ctaagcctat
     6901 gttcagctgt gaaagattta gtaaagagct tgaaaaatca ccattcagca ttaaaaaatc
     6961 ttgacctgcc tgataaaggt taacagctaa agattcggct tttttctgac agacaagcct
     7021 agcttctgga ggcaatttcg caatcactgc cttcttacca gccttgaaaa taccagcttt
     7081 ctgctctgca attgcttcta gactatcacc caaggtttct tgatggtcaa gcccaatgga
     7141 ggtgatgaca gcaagctctc cagttaccac attggtcgtg tcaagtaagc caccaattcc
     7201 cacttctaat aaaaccaaat ccacctcttg ctccctaaaa taaagaaaag caactaaggt
     7261 cagcaattca aaaaaggaca actggtcagg agtttgcaga agcgttttct ccatctcctt
     7321 gacctgatca gccaaacgga taaagtctgc gtctgctata ggttgcccat taatgcagat
     7381 tcggtcattg atagagacga tatgagggga ggtaaaggtc gcaacttttt tgccatgccc
     7441 cataaataat tccctcataa aagcaatggt agatcctttc ccattagtcc ctgttacgtg
     7501 gataataggg taagactgct caggatttcc taacaaatcc accgcttgct gcattcggcc
     7561 caaacctgat cgaaaattca aaccaatccg actatggagc cattcttcta cttcaaacat
     7621 acacatctcc ttgacaaaag tccaatcaat tatcgcatta aagtatggtt actaataaaa
     7681 acaaggccag gattttcgtc ccgacctctt acctggttag ctaataacta gctactatga
     7741 atgtgaatat gggctaaaaa catccactag atgttccaac tcttctcaat ttctaagagt
     7801 tggggtaaaa atgttcactg gacgttccaa ctcttcccca tttctgggag ttgggctgat
     7861 acagtctccc agactacctg cgtttctaat ttctagcgca gggctaaaaa cgtcccccgg
     7921 acgtttttac tcctccataa agctgttgaa gacttcttca atcatgttcc attcgtcttc
     7981 tgagtcttct gggattggtt gcaattcgcc ttctgttcca tcttcgtttt cgatgaatga
     8041 gtaagcttgg atttcaactt gtccgtcttc gtcttcttct gcgttaactg gtactagaag
     8101 aacatagttt ttaccaaatt cttcttttcc atcaattgtc aaaaggattt caaacaaggt
     8161 ttcatttcct tgctcatcta ctagtgtgat tagttcacgt tcttcgtggt cgtggttatg
     8221 atcgtgtgac atagcctctc ctttatatta aaattttcta tctaaataat tttgtaaaat
     8281 cagctgagct gctaacttat caatgacttt cttgcgctta ttgcgactga tatctgcttg
     8341 ttcaatcaac atgcgctcag cagccactgt tgtcaagcgt tcatcctgat agtctactgg
     8401 taaaccaaaa aactcttcta gctttgctcc gtaggcttga ctagcttcta cgcgcggtcc
     8461 acttgtattg ttcatgtttt taggcaagcc cactacaaat cgttccacct tgtaagtatc
     8521 aaccaattcc ttaacgcggt caaaaccaaa ttggccttgt tcttcattta tctggatgat
     8581 ttcaagccct tgagctgtaa aaccaagcgg atcgctaatc gccaccccta ccgtttttga
     8641 accgacgtcc aatcccataa ttctcatagg ttatagatcg actccttgtc ctttgaggta
     8701 gtaacgaacc aattcctcaa cgatttcatc acgctcatac ttacggattt gatttcgtgc
     8761 attattataa cgaggaacgt aggcagggtc tccactcaat acgtaaccta cgatttggtt
     8821 aattgggttg taacccttat cgttcaacga agcataaaca tctgtcaaag tttcgctaat
     8881 ttctttttta ttggaatcgt ccaatttaaa acgtactgtt tcttcagtaa atcccattct
     8941 aacaccctct ttccttagaa tagtaccatt atagcataat tccttacctt ctacaattca
     9001 ggcagtctat ttatttggat tttctattgt tctgtcgcgc catttgccaa tctatctgaa
     9061 atatagttgc ttggttcatt tttcaaaaga ttttccaaac caatattctt cagatgttcc
     9121 aactgggaag ccttcttgac atccagaact tgaaaatcaa aactagtcgt tgtttgaagt
     9181 tccgttgcgc tcaatagttt tgtttcaagt ttgaaacctg ccaatttacg agcttcaatg
     9241 atagacttat ccttctcctc cgcttcaaga agagcttttt gagtttcctc cactccatgt
     9301 tggtcaatat aagtcttcaa ctcatcagag actggacgtt tttgttggat agttagactc
     9361 aaaaaagtct tgtccttgta agtaattgtt tgtgtctgct ggctaccatc atctgacttg
     9421 ggcaagacca aagtcttagt tacaactgta ttcttctcag cattttcaat aactggcaat
     9481 gccgactgaa gcgtatcttt ttctgttttt gtagctgatc cagtttcttt tttctgtccg
     9541 caaccaacca ggacaaaaag gaaagctaga ctaacaagaa ctattttttt catttctttc
     9601 ttctttcttt ttgaaattaa aatagaataa gactgggaag tgctcccagc cttgatgttt
     9661 atagagctgc acgcaaacgt gcttctgcat tttctacatt acggacagag cgtggtagga
     9721 aggcacgaat atcgtcttcc ttgtagccaa cttgcagacg tttttcatct acaaggattg
     9781 ggctctttaa aattctcggt gtttccataa tcagattgag aacttcattg acactcaaat
     9841 cttcaatatc cactccaagg gctttggcat agcgattttt agacgaaacg atgctggcta
     9901 ttccgttatc tgttttggtt agaatatcca gtaattcttc tctcgtaatt ccttctttac
     9961 caaggttttg ttctttataa cttaactggt gggcattgag ccaggttttt gcttttttac
    10021 agctagtaca acttgagact gtataaattt taatcatgta cctacccctt tcgctacatg
    10081 ttactatcag tttagtctat tatac
//
LOCUS       DAVDHZ010000061         9301 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000061 DAVDHZ010000000
VERSION     DAVDHZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.062"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            147..884
                     /locus_tag="VUR46_002006"
     CDS             147..884
                     /locus_tag="VUR46_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5457359.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRHDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEGR"
     gene            881..2572
                     /locus_tag="VUR46_002007"
     CDS             881..2572
                     /locus_tag="VUR46_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5457360.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLAVVGTFYYRSSSSAIEATIEGD
                     SQTTISQTSHFIQSYIKKLETTSTSLTQQTDVLAYAENPSQDRVKGIQNLFLTILKAD
                     QDLKTVVLVTKSGQVISTDDTVQMKTSSDMMTEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTLDHQSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     MWTLLWASVTSLFAFLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAEETGAYELR
                     EVTRQFNAMLDQIDQLMADIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFQ
                     DSQRVVQVTKSLATYFRLALNQGKDLISLSDEINHVRQYLFIQKQRYGDKLDYEIAEN
                     PAFDHLVLPKLVLQPLVENALYHGIKEKEGQGHIRVSVQKEDTGLVIRIEDDGVGFQA
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSSPQKGTKVEIYINRIETS"
     gene            2688..3251
                     /locus_tag="VUR46_002008"
     CDS             2688..3251
                     /locus_tag="VUR46_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET5457361.1"
                     /translation="MNETQIQRETRQILEDVLEKANLKQGSIFVLGLSSSEVIGGQIG
                     KESSQEIGELIVETILGILGTRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVLPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPLLREIGHA
                     HVTALASRPKLIGGARAHYPQDSIRKS"
     gene            3273..9209
                     /locus_tag="VUR46_002009"
     CDS             3273..9209
                     /locus_tag="VUR46_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5457362.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVDKEVI
                     SQEAKDLIQTGNPDGDEVVYGLVYQKAQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASAFLVGAMGLVVLPNAGAVDPVATLAPASREDVVEMEGYRYVGYLSGEILKRLGLD
                     TVLEEASVKSGEVTVVEVETPQSTTNQEQVRPENQAVETEEAPKEQAPRTEESPKEEP
                     KSEVNPTDETLPKVEEEKEVSAEPAPVEEVSGVVESKTDEQAPVKSESQPSDKPAEES
                     KVATPVEQPKIPEQPVQPRTPKESSQEENPTENRGAEETPKQEDEQPAVIETKDEAAN
                     QLVEEPKVETPAIEKQTGPAEEPKVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVE
                     KAPKQEESTPDAKVEETVEPKEETKTAKDTQEEGHVDEALAQEQLPEYKVTEGTLVEE
                     TTTELNYKTETTDDPTKYTDEETVLRTGEKGSQVTKTIYKTVEGVKTDQVLSTSTEVT
                     KEHVNQQVSRSTKPIEGTLVEESLEKIPFKEKIEEDDQLKKGSEVVAQEGKEGQKKIT
                     KTFNTIKGVKTEDAPKVIEEVIEVPQDKILKRGTKIFEKPVLTITAVESKDLKRTSDV
                     KYSLENPSKATIKSITLTLKKGDEIVKTLIVSPDNLTASLTDLQYYKDYKLETKMVYD
                     RGEGDEEEVLNEESLRIDLKKIEIKDIKSTKLIKVSENKEEIDDTNFTTIPTDKNNYY
                     LKITTNDNKTNRLAVKSITEETVDGENFYKITSEATDLIQHTKEEQIKNEYTYYIAKP
                     KQKENNVYYDFGELVEAIQNNPEGDYKIGESLNATNIKPNGKSYITKKFKGSLTSTDG
                     NKFAIHNLANPLFNEIENATIKDLIFSNVNINKPNTEQIATLGKDATNTIIENIKITG
                     SIVGSNDVAGVVNNLNNGSKMKNVAVIGKLHTEGKKGWSISGLVNNQRKANIERVYTD
                     VEITGERARGSALVSTLDRGTDPRDVRANGHIKKAVAKGSINLKNNVETGGVISKNWP
                     YGFMEDVISYVKVTNAEKLYGSGDIGDDDFGFPYLSRVVSVAGEATGNVTRKNANRLK
                     EISKEEADKKLEDFGITAKDFEAPTLLVDKLNNNISKDDEYKTTQDYDKTKEQAYRNI
                     AKLQPFYNKEWIVNQGNKLTNENLLNKKVISVIGMKDNDFVTDLSEVNKILVHYSDKT
                     KDIFTVVQKDSNVSQIKEYSINELKDIVYTPNMIAKDRDSIASKIKEKLNSVELQSDG
                     MYNLMDKRNNPQENTTERRKRYVRDLFLEESFEEVKNNLDNLVNKLLLNYDFQLNESK
                     ASEDVLLQKIEANKEKIMLGLAYLNRYYGINFDNMNIKEIMLFKPDFYGKNVNFLDFL
                     IKIGSSEKNVKGDRTLEAYRETIGGIIGINELNGFLHYNMNLLTEYTNINDWFKDATK
                     KNVYIVEPETSIEDFKNKKHRAYDGLNNDVHSRMILPLLNLKKAHIFLISTYNTMAYS
                     AFEKYGKNTEEARNEFKKEIDKVAKAQQDYLDFWGRLASDKVRNKLLKSQNVVPSPVW
                     DNMNAPGYGWLDKYGYKDGSSDYAPSRELFGPTGRYFPPNWNMGAMAKIWDNPYKEES
                     VYYMVTDMISDFGISAFTHETTHINDRLAYLGGWRHREGTFVEAFAQGMLQSPSVSNP
                     NGEYGALGINMAYERNNDGNQWYNYNPNKLKNRQEIDDYMKRYNEAMMLLDYVEAESV
                     LSKNLSDNSQWFKKVDRKMREKGSYNNNLVAPNQWDLVRDLNEDEKVIKLNTIKDLVD
                     NNFATRHGVGNGVFKPEDFTPNSAYVTVNMMAGIYGGNTSEGAVGALSFKHNTFRMWG
                     YFGYEKGFVGYASNKYKDIANKENNGLLSDKLIIQKVSEGRFNTLEEWKNSWYEEIYN
                     KATTKGFVPISVDNEQISTYARLKELFNEAVQKDLNELSNQTIKNKYRHTVALKEKVF
                     KQLLKESDGFSGDLFNTSQA"
BASE COUNT         3411 a         1465 c         1930 g         2495 t
ORIGIN      
        1 tacaacctca aagcggtatt ttgagaaacc tgtggctatc ttcctagttt actttttgat
       61 tttcattgag tataagaggt atttcctaag cagttagagg agaattttgc tatactgata
      121 ctagtaagtg acataaggag agaagcatga cctacacaat cttaatcgta gaagatgaat
      181 atctggtaag acaaggtttg actaaactgg tcaatgtagc agcctacgat atggaaatca
      241 tcggtcaggc tgaaaatgga aggcaggctt gggaattgat ccaaaagcag gtgccagata
      301 tcattttaac cgatatcaac atgcctcatc taaatggcat ccagttggcc agtctggtac
      361 gagaaaccta tcctcaggtt catttggtct ttttaacagg ttacgatgat tttgattatg
      421 ccttgtctgc tgtcaaacta ggtgtggacg actacctgct caaacccttt tctcgtcatg
      481 atattgagga aatgttgggg aaaatcaaac aaaaactaga caaggaagag aaagaagagc
      541 agttacaaga tttattgact aataggtttg aaggaaacat ggcccagaaa atccagtctc
      601 atctggctga tagccaattt agtttaaagt ctttagccag tgacttaggt tttagtccga
      661 cctatctgag ttccttgatt aagaaagagt tgggcttgcc ttttcaggat tatctggtga
      721 gagaacgtgt taaacaagct aagctcttgc ttttaactac agatctgaag atttatgaga
      781 ttgcagagaa ggttggtttt gaagatatga actattttac ccaacgtttt aagcagattg
      841 caggtgtgac acctcgtcag tttaagaagg gagaaggccg atgaagcgtt cttctctttt
      901 agttagaatg gttatttcca tctttctggt ctttctcatt ctcctagctg tggttgggac
      961 tttctactat cgatctagtt catcagccat tgaggctacc attgaaggcg atagccaaac
     1021 gactatcagt cagactagcc actttatcca gtcttatatc aaaaaattag aaacgacctc
     1081 gaccagtttg acccagcaga cggatgtcct agcctatgct gagaatccta gccaagacag
     1141 agtaaaggga atccaaaatc tgtttttgac catcttgaag gcggatcagg acttgaaaac
     1201 ggtggtactg gtaaccaagt caggtcaggt catttctaca gatgacactg tgcagatgaa
     1261 aacatcctca gatatgatga ctgaggattg gtaccaaaag gctattcatc agggagccat
     1321 gcccgttttg accccagcgc gtaagtcaga cagccaatgg gtcatttctg ttactcaaga
     1381 acttgttgat gcgaagggag ccaatctggg tgtgcttcgt ttggatattt cttatgaaac
     1441 tctggaagcc tatctcaatc aactccagtt ggggcagcag ggctttgcct tcattatcaa
     1501 tgaaaaccat gaatttgtct accatcctca acacacagtt tatagttcgt ctagcaaaat
     1561 ggaggctatg aaaccctaca tcgagacagg tcagggctat acactagacc accaatccta
     1621 cgtcagtcag gaaaagattg caggaactga ttggacggtg cttggcgtgt catcattgga
     1681 aaagttagat caggttcgga gtcaactcat gtggaccttg ctttgggcta gtgtcacatc
     1741 tctttttgcc tttctctgct tggtgtggtt cagtctcaaa cgctggattg ctcctttgaa
     1801 ggatctgaga gaaaccatgc tggaaattgc ctctggtgct caaaatcttc gcgccgaaga
     1861 aactggtgcc tatgaactga gagaagtgac tcgtcagttc aatgccatgc tggatcagat
     1921 tgatcaactg atggcagata ttcgtagcca ggaagaaacg acccgtcagt accaacttca
     1981 agccctatca agccagatta acccccattt cctctataac accttggata ccatcatctg
     2041 gatggctgaa tttcaggaca gtcagcgagt ggttcaggtg accaagtcct tggcaaccta
     2101 tttccgcttg gcgctcaatc aaggcaagga cttgatttcc ctgtctgacg aaatcaatca
     2161 tgtccgccag tatctcttta tccagaaaca acgctatgga gataagttag actatgaaat
     2221 tgctgaaaat cctgcctttg atcatctagt tttgcctaag ctggtgttgc aaccccttgt
     2281 agagaatgct ctttaccatg gcatcaagga aaaggaaggt cagggacata ttagggtctc
     2341 tgtccagaaa gaggatacag gcttggtcat ccgtattgag gatgatggcg ttggcttcca
     2401 agctgctggc gatagtagtc aaagtcaact caaacgtggg ggagttggtc ttcaaaatgt
     2461 cgaccaacgg ctcaaacttc attttggagc caattaccag atgaagattg attctagccc
     2521 ccaaaaaggg acgaaagtgg aaatatacat aaatagaata gaaactagct aactcccagt
     2581 caattctggg agttttatgc gtaattgggc aagctttcca ggttgtctat cttgctaaaa
     2641 acaagaaaaa acggtatgat agaagagtga taaaagaggt ggcagagatg aatgagacac
     2701 agattcaaag agaaacacgt cagatattag aagatgtttt agagaaggcc aatttgaaac
     2761 aaggctccat ctttgtttta ggcctttctt ctagtgaggt gataggtggt cagattggga
     2821 aagaatccag tcaagagatt ggcgagctga tagtggagac tatcttgggt attctaggta
     2881 ctagaggtat ccatttagct gttcaaggtt gtgaacatgt caatcgggcc ctcgttgttg
     2941 aacgtcaggt ggcagagcag tttggtctgg aaattgtcag tgtccttcct acacttcatg
     3001 caggaggttc ggggcagtta gcagccttca agttcatgca ggatccagtt gaggttgaat
     3061 ttatcaaggc tcatgctgga ttggatatcg gagacactgc aattggcatg catgtcaagc
     3121 atgttcaggt tccgattcgc cctcttttga gagagattgg tcatgcccac gtaacggcac
     3181 tggctagtcg tccaaaatta attggaggtg cgcgtgcgca ctatccgcaa gattctatta
     3241 gaaagtcgta agaatgaata aaggagatga aagtgtttaa aaaagatcgt ttttcaattc
     3301 gtaagattaa gggagttgta ggttctgtat ttcttggaag ccttttaatg gctccttctg
     3361 tagtggacgc agccacctat cactatgtag ataaagaggt tatttcacaa gaagctaaag
     3421 atttaatcca gacaggaaat cctgatggag atgaagttgt ctatggtttg gtgtatcaaa
     3481 aagctcagtt gcctcaaaca ggcacagaag catctgtttt gacagctttt ggtttgctga
     3541 ctgttgggag cttgctttta atctacaaga gaaagaaaat tgctagcgcc tttctagttg
     3601 gagctatggg attggtagtc cttcctaatg caggggctgt agacccagtt gcgaccctag
     3661 caccggctag tcgagaggat gttgttgaaa tggagggcta tcgctatgtg ggttatctat
     3721 caggtgaaat cctcaaaagg cttggtttgg acactgtttt agaagaagct tcagttaaat
     3781 ctggagaggt gactgtagtc gaagttgaga ctcctcaatc aacaacaaat caggagcaag
     3841 tgaggccaga aaaccaagca gtagagacag aggaagctcc aaaagaacaa gcacctagaa
     3901 cagaagaaag tccaaaagaa gaaccaaaat cggaggtaaa tcctactgac gaaacccttc
     3961 ctaaagtaga agaggaaaaa gaagtttcag cagaaccagc tccagttgaa gaagtaagtg
     4021 gagtagttga gtcaaaaaca gatgaacaag caccagtcaa atcggaaagt caaccatcag
     4081 acaaaccagc tgaggaatca aaagttgcaa ctccagtaga acaaccaaaa attccagaac
     4141 aacccgttca accaaggaca ccaaaagaat catcacaaga agaaaatcct acagaaaata
     4201 ggggagcgga agagacaccg aaacaagaag atgaacagcc agcagtaata gaaacaaaag
     4261 atgaggctgc taatcaactt gtcgaagaac caaaagttga aacgcctgct atagaaaaac
     4321 aaacgggacc agctgaggaa ccaaaagttg aacaagcagg tgaaccagtc gcgccaaggg
     4381 aagacgaaaa ggcaccagtc gagccagaaa agcaaccaga agctcctgaa gaagagaagg
     4441 ctgtagaaaa agccccaaaa caagaagaat caactccaga tgccaaggtt gaagaaactg
     4501 tagaaccaaa agaggagacc aaaacagcta aagatacgca agaagaaggt cacgtggatg
     4561 aggctcttgc tcaagaacaa ttacctgagt ataaagtgac tgaaggaaca cttgttgaag
     4621 aaacaactac agaacttaac tataaaactg aaacgactga tgatccaact aagtatacag
     4681 atgaagaaac tgtcctacga actggtgaaa aaggaagtca agttacaaaa acaatctata
     4741 aaacagtaga aggtgttaaa actgaccaag ttctttcaac cagtacggaa gtgaccaagg
     4801 agcatgtaaa tcaacaggta agccgtagta caaaaccaat tgaagggact cttgtagaag
     4861 aaagtcttga aaagattcca tttaaagaaa agattgaaga agatgatcaa ctgaaaaaag
     4921 gttcagaagt cgtagctcaa gaaggcaaag aaggtcagaa aaaaattact aagaccttta
     4981 ataccatcaa aggagttaaa acagaagacg ctccaaaagt tatagaggaa gtcattgagg
     5041 tccctcaaga caaaattttg aaacgtggta ccaaaatttt tgaaaaacca gtattgacta
     5101 taacggcggt tgagtctaag gatttgaagc gtacttcaga tgttaaatac agtctagaaa
     5161 atccaagcaa ggcgaccatt aaatccatca ccttaactct gaaaaaaggt gatgagattg
     5221 tgaaaacatt gattgtttca cctgacaact tgacagccag cctgacagat ttgcaatact
     5281 acaaggatta taaacttgaa acaaagatgg tttatgaccg tggtgagggt gatgaggaag
     5341 aagttctgaa tgaagaatct ttaagaattg accttaagaa aattgagatt aaagatatta
     5401 agtctacgaa actaataaaa gttagtgaaa ataaagaaga aatagatgat actaatttca
     5461 caacaattcc tacagataaa aataattatt atttaaaaat cacaacaaat gataataaga
     5521 caaatagatt agcagtaaaa tctattacag aagaaacagt agatggagaa aacttttata
     5581 agattacttc agaagcaact gatttaattc aacatactaa agaagaacaa atcaaaaatg
     5641 aatatactta ttatatagca aaaccaaaac aaaaagaaaa caatgtttac tatgattttg
     5701 gagaattagt tgaagctatt caaaacaatc cagaaggaga ttataaaatc ggagaaagtt
     5761 tgaacgctac taatattaaa ccaaatggaa aatcttatat tacaaagaaa ttcaaaggaa
     5821 gtttaacaag tactgatggg aataagtttg ctatacataa cttagctaat ccattattta
     5881 atgaaataga aaatgctaca ataaaagatt tgattttttc taatgtaaac ataaacaaac
     5941 caaacacaga acaaatagca acattaggaa aggatgcaac aaatacaata attgaaaaca
     6001 ttaaaattac tggaagtatt gtaggtagta atgatgtagc tggtgttgtt aataatttaa
     6061 ataacggtag caagatgaaa aatgttgctg ttataggaaa attacacaca gaagggaaaa
     6121 aaggttggag tatatctggt ttagttaata accagagaaa agcaaacatt gaaagagttt
     6181 atacagatgt agagattaca ggagaaagag ccagaggttc agctttagtt tcaacattag
     6241 acagaggtac ggatccaagg gatgtgcgag ctaatggaca tattaaaaaa gctgtagcaa
     6301 aaggatcaat aaacttaaaa aacaatgtgg aaacaggtgg agttatttct aaaaactggc
     6361 cttatggatt tatggaagat gtaattagtt atgtgaaagt aactaatgct gaaaaactgt
     6421 atggttcagg agacattgga gatgatgact ttggattccc ttatttaagt agagttgtta
     6481 gcgtagctgg agaagcaact ggtaatgtaa caagaaaaaa tgcgaataga cttaaagaga
     6541 tttctaaaga agaagctgat aaaaaattag aagattttgg tattactgcc aaagattttg
     6601 aggctccaac attattagta gataagttga ataataacat atcaaaagat gatgaatata
     6661 aaacaacaca agattatgac aaaacaaaag aacaagcata tagaaatatt gctaaattac
     6721 aaccttttta taataaagaa tggatagtta atcaaggaaa taaattaact aatgagaact
     6781 tattaaataa aaaagttata tctgttattg gaatgaaaga taatgacttt gttacagatt
     6841 tatccgaagt aaacaaaata ttagtacatt attcagacaa aacaaaagat atttttacag
     6901 ttgtacaaaa agattcaaat gttagccaaa ttaaggaata tagtattaac gaattgaaag
     6961 acattgttta tacacctaac atgatagcaa aagatagaga ttctatagca agtaaaatta
     7021 aagaaaaatt aaattctgtt gaattacaat ctgatggaat gtataattta atggataaac
     7081 gtaataatcc tcaagaaaat acaacagaaa gacgaaaaag atatgtaaga gatttattct
     7141 tagaagaaag ttttgaagaa gtgaaaaata atttagataa cttagtaaac aaattgttat
     7201 taaattatga ttttcaatta aatgaaagta aagcttcaga agatgtttta cttcaaaaaa
     7261 tagaagccaa taaagaaaaa ataatgctag gattagctta tttaaatcgc tattatggaa
     7321 ttaattttga taatatgaat attaaagaaa ttatgttgtt taaacctgac ttttacggaa
     7381 aaaatgttaa cttcttagat ttcttaatta aaataggttc aagtgaaaaa aatgttaaag
     7441 gagatagaac tttagaagct tatcgtgaaa ctataggtgg aataattgga ataaatgaat
     7501 taaatggatt tttacattat aatatgaatt tattaactga atatacaaat ataaacgatt
     7561 ggtttaaaga cgcaactaag aaaaatgttt atattgttga accagaaact tcaattgaag
     7621 atttcaagaa taaaaaacat agagcatatg atggtctaaa caatgatgtt catagcagaa
     7681 tgattttacc tttattaaat cttaaaaaag cacatatatt cttaatttca acatataata
     7741 caatggcata tagtgctttt gaaaaatatg gtaaaaacac agaagaagct agaaatgaat
     7801 tcaaaaaaga aattgataaa gttgctaaag cacaacaaga ttacttagat ttctggggta
     7861 gactagcttc cgacaaagta agaaataaat tactaaaaag tcaaaatgta gttccttcac
     7921 ctgtctggga taatatgaac gcacctggtt atggttggct agataaatat ggatataaag
     7981 atggttcttc tgattatgct ccttcaagag aattatttgg tcctactgga agatatttcc
     8041 caccaaactg gaatatggga gcaatggcta aaatctggga taatccatac aaagaagaat
     8101 ctgtttacta tatggttaca gatatgatta gtgattttgg tatctctgct ttcacacacg
     8161 aaacaactca tattaatgat agattagctt atcttggagg atggcgacac agagagggaa
     8221 cttttgtgga agcttttgct caagggatgt tgcaatctcc atctgtttct aatcctaatg
     8281 gtgaatatgg agcccttggt atcaacatgg cttatgaaag aaataatgat gggaaccaat
     8341 ggtataatta caatccaaat aaattaaaaa atagacaaga aattgatgat tatatgaaac
     8401 gatataatga agcaatgatg ttactagact atgttgaagc tgaatctgtt ttaagtaaaa
     8461 acttatctga taacagtcaa tggtttaaga aagttgacag aaaaatgcgt gaaaaaggaa
     8521 gttataacaa taatttagtt gctccaaacc aatgggattt agttcgcgac cttaatgagg
     8581 acgagaaagt aattaaatta aatactataa aagatttagt agataataac tttgctacta
     8641 gacatggtgt tggaaacggt gtgtttaaac cagaggactt cactccaaac tctgcttatg
     8701 taacagtaaa tatgatggca ggtatttacg gaggaaacac aagtgaaggt gctgttggtg
     8761 cattgtcgtt taaacacaac acatttagaa tgtggggata ttttggatat gaaaaaggtt
     8821 ttgttggata tgcttcaaat aaatacaaag atattgctaa taaagaaaac aacggcttac
     8881 taagtgataa gttaatcatc caaaaagttt cagaaggtag attcaacact cttgaagaat
     8941 ggaaaaattc ttggtacgaa gaaatatata ataaagctac aactaaagga tttgttccta
     9001 tatctgttga taatgaacaa atttcaactt atgctagatt aaaagaatta tttaatgaag
     9061 cagtacaaaa agatttaaat gaattgtcta atcaaacaat taaaaataaa tatagacata
     9121 ctgttgcatt aaaagaaaaa gtctttaaac aattactaaa agaatcagac ggtttctctg
     9181 gtgatctatt taatacatca caagcataag atgaataaaa tcggctcttt gtcaactgta
     9241 gtgggttgaa gaaaagctaa gctcgagaaa ggacaaattt cgtcctttct tttttgatat
     9301 t
//
LOCUS       DAVDHZ010000062         8987 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000062 DAVDHZ010000000
VERSION     DAVDHZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.063"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(637..1665)
                     /gene="queA"
                     /locus_tag="VUR46_002010"
     CDS             complement(637..1665)
                     /gene="queA"
                     /locus_tag="VUR46_002010"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET5457363.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVSTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVNN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPRYGWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            1816..2523
                     /locus_tag="VUR46_002011"
     CDS             1816..2523
                     /locus_tag="VUR46_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET5457364.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            2663..2839
                     /locus_tag="VUR46_002012"
     CDS             2663..2839
                     /locus_tag="VUR46_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET5457365.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            2969..3904
                     /locus_tag="VUR46_002013"
     CDS             2969..3904
                     /locus_tag="VUR46_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET5457366.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIVILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            3897..4685
                     /locus_tag="VUR46_002014"
     CDS             3897..4685
                     /locus_tag="VUR46_002014"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET5457367.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            4686..5069
                     /locus_tag="VUR46_002015"
     CDS             4686..5069
                     /locus_tag="VUR46_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET5457368.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            5085..5474
                     /locus_tag="VUR46_002016"
     CDS             5085..5474
                     /locus_tag="VUR46_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET5457369.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEQAEALDDSEEIVIDITEE"
     gene            5558..6688
                     /locus_tag="VUR46_002017"
     CDS             5558..6688
                     /locus_tag="VUR46_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET5457370.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            6693..7430
                     /locus_tag="VUR46_002018"
     CDS             6693..7430
                     /locus_tag="VUR46_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET5457371.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSNFDKKLIRGPKYESLEELISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            7441..8214
                     /locus_tag="VUR46_002019"
     CDS             7441..8214
                     /locus_tag="VUR46_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET5457372.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVNVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVADLPIAPTHVVSSLAEWDFDEN"
     gene            8204..8821
                     /locus_tag="VUR46_002020"
     CDS             8204..8821
                     /locus_tag="VUR46_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET5457373.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLPIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
BASE COUNT         2591 a         1664 c         2042 g         2690 t
ORIGIN      
        1 tttttttcta caataaaata ggctccataa tatctatagt ggatttaccc actacaaata
       61 ttatagagcc aaaaagtgaa caagcctagt cttctgtaca ttagaattca gatttgttca
      121 ctttttgttt aatactcaat gaaaatcaaa gagcaaacta gaaaactagt cgcaggttgc
      181 tcaaagtact gctttgaggt tgtagataga actgacgaag tcggtcacat atataattca
      241 aggtgacgtt gacgcggttt gaagagattt ttgaagagta taagtctttg attttgagac
      301 taaggagagt cagggtcaaa gtagtgaatg attctgaaat aactcataac agtctcttga
      361 gaggacagat aagagtaaca aatatggtgc tactcatgtg tcttgcattt taatttacaa
      421 acagcgaaga aagtatagga agctgaaata aaatatagat gaatcaattt ggagagtcaa
      481 cgcaatctat ggcaatattt tcgaagctag ggggaagcat tttaatttca atgtactagg
      541 cgtcttctat agctagctag agtttcaatt gtagatgttc tttgaaataa tatcttagcg
      601 atttattggt attagaagat ttagagaaat tctttctcaa taaataaaca tggcgtcacc
      661 aaaactgaag aagcggtagt gttcttggat ggcatggtgg taggcatcta agactaattc
      721 acggcctgca aaggcagaaa ccaacatgac cagagttgat tttggcaggt ggaagttggt
      781 tgagaaggca tccacgacct tccacccata cctaggcttg ataaagatat tggtccaacc
      841 agaatctgct tggatttgcc catcaaactt ggaaccaata gtttccaagg tgcggataga
      901 agtggttcca acagcgatga cacgaccacc attttctttg acagagcgaa gggtggcagc
      961 agcttcttca gaaagttggt agaattctga gtgcatttcg tgttcgtcca gattattcac
     1021 agaaacaggt ctaaaggttc cgagtccgac atggagagtc agatagacta gatgaacacc
     1081 cttagcttgg atttctgcca gcagttcttt ggtgaagtga agaccagcag tcggtgctgc
     1141 agcagagccg ctttccttgg cgtagacggt ttgataacgt tcacggtcat ctaatttttc
     1201 gtggatataa ggtggcagag gcatttctcc cagactttcc aagacttcta ggaaaattcc
     1261 ttggtattca aagcggacaa tgcgtccccc gtgggtcaat tcttctgtaa cgacagcgct
     1321 gaggcggcca tcaccaaagc tgatacgagt actgaccttg aggcgtttgg caggtttagc
     1381 cagaacttcc cactcgtctc cactagtgtt cttaaggagg agaagttcca catgacctcc
     1441 tgtctccact ttttgaccat agaggcgggc agggagaact cgggtgtcgt tcatgacaag
     1501 ggcatcacca ggttccagca tatcaataat agagtggaag tgtttatctt gcatttctcc
     1561 tgtctcacgg ttgacgatga ggagtttgga ggcatcacgt ttttcaaggg gcgtttgggc
     1621 aatcaattcc tctggcaagt ggaaatcaaa atcagctgta ttcatatatc tgttcattct
     1681 ttctaagttc taatactatc cattataaca cgtttcaagt ttggacgctc tttttttaga
     1741 aattaaatcg ttttcacttg acaaaaattg gtctatacca tataataaat atagacagaa
     1801 atggaggatg aaaagatgaa agttattaaa gttgaaaacc aagttcaagg tggaaaagtt
     1861 gcttttgaga ttttgaagga aaaattggct aatggagctc aaactctagg acttgcgaca
     1921 ggaagtagcc cacttgaatt ttacaaggaa attgttgaga gtgaccttga tttttcaaat
     1981 ctaaccagtg tcaaccttga tgagtatgtg ggccttgatg gggacaatcc acagtcttat
     2041 cgttacttca tgcaagaaaa cttgttcaac caaaaaccat ttaaagaaag tttcttgcct
     2101 cgtggtgtta aggacaatgc tgaagctgaa gttgaacgct acaaccaaat tttggctgac
     2161 catccagttg acctccaaat cttgggaatc ggtcgcaatg ggcatatcgg ctttaatgag
     2221 cctggtactc catttgacag tcaaacgcat ctagtagaac ttgaccagtc tactatcgaa
     2281 gccaatgcac gcttctttgc taagattgaa gacgtcccaa cccaagctat ttcaatgggg
     2341 attaaaaaca ttttggatgc caagtctatt attctttttg cttacggtga gtcgaaagca
     2401 gaagccattg ccggaacagt atctggccca gtgactgaga acctacctgc aagtagcctc
     2461 caaaatcacc ctgatgtaac catcatcgca gatgctgaag cgcttagctt actcgaaaaa
     2521 taaaaaagca atgttctatt gaacgctttc aactcttgta taaatggaag aaaaaatcaa
     2581 aattaaaccg catttttgct tgacaattat tccttttacg tgtagaatga aatagatatt
     2641 gaacttgaag ggagtgaaaa aaatgtctaa aacagtagta cgtaagaatg aatctcttga
     2701 cgacgcactt cgccgtttca aacgtgcggt tactaaagct ggtactcttc aagaaacacg
     2761 caaacgtgaa ttctatgaaa aaccttctgt aaaacgtaaa cgtaaatcag aagtagctcg
     2821 taaacgtaaa aaattctaat tgaaatgaaa ggctagagaa atctagtcct ttttctttta
     2881 aataaatact ccaaagcctg caaaaatctg aaacttcctc ctacaatttg atataataga
     2941 gagaagaact catttgaagg aggaaatgat gtcggtttta gtaaaagaag tgattgaaaa
     3001 gcttagacta gacattgtct atggcgaacc agaattgctt gaaaaggaaa tcaatacagc
     3061 ggatattacg cgacctggtc ttgaaatgac aggctatttt gactactata caccagagcg
     3121 gattcaactt ttggggatga aggagtggtc ttatctgatc agcatgcctt ccaacagccg
     3181 ttatgaagtt ttgaaaaaaa tgtttctacc tgagacacca gcagtcattg ttgcccgtgg
     3241 tttggtggtt ccagaggaga tgttaaaggc tgctagagaa tgtaagattg ttattttaac
     3301 cagccgtgca gctaccagtc gtttatctgg agagttatct agctatctgg attctcgttt
     3361 ggcagaacgt accagtgtgc acggtgtctt gatggatatt tatgggatgg gcgtcttgat
     3421 tcagggagat agtggaattg gtaagagcga gacaggtctt gagcttgtca aacgtggtca
     3481 ccgtttggta gccgatgacc gtgtcgatat ctttgccaag gatgagatta ctctctgggg
     3541 tgaaccagct gaaattttga aacacttgat tgaaattcgt ggggttggta ttatcgatgt
     3601 tatgagtctc tacggtgcga gtgctgtcaa ggattcttca caggttcagc ttgctgtcta
     3661 tttggaaaat tacgatacgc ataagacctt tgatcgtctt ggaaacaatg cagaggaact
     3721 tgaagtttct ggcgtagcca ttcctcgtat tcgtattcca gttaaaacag gtcgtaatat
     3781 ctctgttgtg attgaggcag ctgccatgaa ttatcgtgcc aaggaaatgg gctttgatgc
     3841 gacccgtttg ttcgacgaac gactgacaag tctcatcgct cgaaatgagg tgcaaaatgc
     3901 ttgatccaat tgctattcaa ctaggacccc tagctattcg ttggtatgcc ttatgtattg
     3961 tgacaggctt gattcttgcg gtttatttga ccatgaaaga agcacctaga aagaagatca
     4021 taccagacga tattttagat tttatcttag tagcctttcc cttggctatt ttaggagctc
     4081 gtctctacta tgttattttc cgatttgatt actatagtca gaatttagga gagatttttg
     4141 ccatttggaa tggtggtttg gccatttacg gtggtttgat aactggggct cttgtgctct
     4201 atatctttgc tgaccgtaaa ctcatcaata cttgggattt tctagatatt gcggcgccta
     4261 gcgttatgat tgctcaaagt ttggggcgtt ggggtaattt ctttaaccaa gaagcttatg
     4321 gtgcaacagt ggataatctg gattatctac ctggctttat ccgtgaccag atgtatattg
     4381 aggggagcta ccgtcaaccg actttccttt atgagtctct atggaatctg cttggctttg
     4441 ccttgattct gatttttaga cggaaatgga agagtctcag acgaggtcat atcacggcct
     4501 tttacttgat ttggtatggt ttcggtcgta tggtcatcga aggtatgcga acagatagtc
     4561 tcatgttctt cggccttcga gtgtcccaat ggctgtcagt tgtccttatc ggtctcggta
     4621 taatgatcgt tatttatcaa aatcgaaaga aggcccctta ctatattaca gaggaggaaa
     4681 actaaatgtt agaagttgca tatattcttg ttgccctagc tttgattgtc tttttggtct
     4741 atctgatcat tactgtacaa aagcttggtc gtgtcatcga tgaaacagaa aagacgatta
     4801 aaaccttgac ttcagatgtg gatgtgacct tgcatcacac caatgagttg ttggctaagg
     4861 tcaatgtctt ggcagatgat atcaatgtca aggtggctac gattgatcca ctcttcagtg
     4921 ctgttgcaga tttatctcta tctgtttcag acctcaatga ccatgcgcgt gtcttgagca
     4981 agaaagcttc atcagctggt tcaaaaacac tcaagactgg tgcaagtctg tcagctcttc
     5041 gtcttgcaag taaatttttc aaaaaataaa aaaggagaat ccttatgggt aaattatcct
     5101 caatcctttt aggaacggtt tcaggtgcag ctcttgcctt gtttttaaca agtgataagg
     5161 gcaaacaagt ttgcagtcag gctcaagatt ttctagatga tttgagagaa gatccggagt
     5221 atgccaagga gcaagtctgt gaaaaactga cagaagttaa ggagcaggct acagattttg
     5281 ttctgaaaac aaaagaacag gttgagtcag gtgaaatcac tgtggacagt atacttgctc
     5341 aagctaaatc ctatgctttt caagcgacag aagcatcaaa aaatcaatta aataatctca
     5401 aggagcaatg gcaagaacaa gccgaagctc ttgatgactc agaagagatt gtgattgata
     5461 taacagaaga ataaaccatc accatctccg gacggactat gtatctgggg atggtgattt
     5521 ttatctggaa tctagtcttt gtggtataat aattactatg cagaaaaaac caacgtcagc
     5581 ctatgtgcac atcccatttt gtacccagat ttgttattat tgtgattttt caaaggtctt
     5641 catcaaaaat cagccagtcg acagctattt agagcatctg ctggaagagt ttcgttctta
     5701 tgatattgaa aagttgtcaa ccctttatat cggtggtgga acaccgacag ccctgtcggc
     5761 tccgcaactg gaggtgttac tgaatggctt gactaaaaac ttggatttgt ctgtcttgga
     5821 agagttgacc attgaagcca atccaggcga tttggatgcg gataagatag ctgttttgaa
     5881 aaattcggct gtcaatcgtg tttcgctagg tgtccagacc tttgatgata agatgttgaa
     5941 aaagattggg cgcagtcatt tggagaagga tatttatgaa aatatcgatc gcctgaaact
     6001 ggctggtttt gacaacatct ccattgattt gatttatgct ctgcctggtc agaccatgga
     6061 gcaagtaaag gaaaatgtgg ctaaagccat tggactggat attccccaca tgagtttgta
     6121 tagtttgatt ttagaaaacc atacggtctt tatgaaccgg atgcgacgtg ggaaattgcc
     6181 tctgcctaag gaggaactag aagcggagat gtttgagtac atcattgcag agctggagcg
     6241 agcgggtttt gagcattatg agatttctaa tttctccaaa cccggctttg aaagtcgtca
     6301 caatctcatg tactgggaca atgctgaata ctatggtatt ggtgcagggg catctggtta
     6361 tgtcaatgga gtacgctata aaaatcatgg tcccattcgt cattatctca gtgcggttga
     6421 ggaaggcaat gcttgtatta cagaagatca cctgagtcaa aaggagcaaa tggaagaaga
     6481 aatgttcttg ggactccgca agaaatccgg ggtttccatg gcgcgatttg aggaaaaatt
     6541 tggacagtct tttgctggac tttatggaga aattgtcaga gatttggttc aacaaggcct
     6601 catgcagatt gagggtgacc acgttcgcat gacaaagaga ggtctctttt tgggagatac
     6661 tgtagcagaa cgatttattt tggagtagga tcatgggctt aacttatcaa atgaaaatga
     6721 aaattccttt tgatatggct gatatgaacg gtcatatcaa acttccagat gtgattttgc
     6781 tgtcactgca agtttcaggg atgcagtcga ttgaactggg agttagtgat aaggccattt
     6841 tggaagacta taatctggtc tggattatcg cagaatatga tattgaggtg gttcgtttgc
     6901 ctcgttttgc ggaagaaatt accatcgaaa cggaagcctt gagctacaat cggctttttt
     6961 gctaccgtcg ctttactatt tataatgaag cggggcagga gctcatccat atgatggcga
     7021 cctttgttct catggaccgc gacagtcgaa aagtccatgc tgttgaacct gagattgtgg
     7081 ctccttacca gtctaatttt gataaaaaac ttatccgtgg accgaagtat gagtccttgg
     7141 aagagctgat cagcaaggat taccatgttc gtttttacga cttggatatg aatggtcatg
     7201 tcaataacag taaatacttg gactggattt ttgaggtcat gggagcggat tttttgaccc
     7261 actatattcc caagaaaatc aacctcaagt atgtcaagga agttcgacca ggtggggtga
     7321 ttacatcggc tgttgaacgg actggactgg aaagcaagca tgaaattaca agtgatgggg
     7381 ttatcaatgc ccaagcaatc attacttggc aagaaataaa aaaggcttag ggagaaatag
     7441 atgaaatata aaggctattt aattgattta gacggaacca tttataaggg gaaagaccga
     7501 atccctgctg gagagacttt tgttcatgaa ttgcaaaagc gggacattcc ctatctcttt
     7561 gtaaccaaca atacaactcg cactccagag agtgttaagg agatgttggc tcagaatttt
     7621 aatatcgata cgcccctatc gactgtctac acagcgactt tggcaaccat cgactatatg
     7681 aatgatttgg ggcttgaaaa gaccgtcaat gttgtcggag aagcaggact caaggaagcc
     7741 atcaaggcgg ctggttatgt ggaagacaag gaaaaacctg cctacgtggt agttggtctg
     7801 gattggcaag tcgactatga aaaatttgcc acagcaactc ttgctattca aaagggtgcc
     7861 cattttatcg gaaccaatcc tgacctcaac atcccgacgg aacgcggtct tttgccaggt
     7921 gctggctcac tgattacgct gcttgaagta gcgacacgag tgaagccggt ttatatcgga
     7981 aaaccaaatg ccatcattat ggacaaggcg gttgagcact taggtttgga acgtgaagag
     8041 ttaattatgg ttggggacaa ttatttgact gatatccggg ctgggattga caatggcatt
     8101 ccaacgctct tggtgacgac aggttttact aaggcagaag aagtagctga cctgccaatc
     8161 gcaccgacac atgtggtttc tagccttgcg gagtgggatt ttgatgaaaa ctaaattgac
     8221 cttttggggc tctatgctct ttctcctctc cctctcaatc cttctgccca tttatctggc
     8281 ttggattttc tatcctatgg agattcagtg gctaaactta acgaatcgag tctatctaaa
     8341 accagaaacc attcaataca attttcatat cttgatgaat tatctgacca atccttttag
     8401 tcaggtctta cagatgcctg attttcgttc gtcagcagct ggtctgcacc atttcgcagt
     8461 ggtcaagaat ctctttcatt tggttcagct agtagctcta gtgacactgc caagtttcta
     8521 tgtctttgtc aatagaattg tgaaaaagga ctttttgtct ctttatcgaa aaagtctcct
     8581 ggctctagta gtcttacctg tgatgattgg acttggggga gttttgattg gttttgacca
     8641 attctttact cttttccatc aaattctctt tgtgggagat gatacctggc tttttgatcc
     8701 agccaaggat cctgttatta tgattttgcc agagaccttc tttcttcatg ccttcctcct
     8761 cttttttgcc ctctatgaaa gcttctttgg ctatctgtgt ctgaaaagtc gtaggaagtg
     8821 aaatgaaaga tgtttttaat ttgcatatat aaatatatat atcgtttaaa accatcgtta
     8881 agagtgaatt aaccaaatcc aattgtgtca atcgttcgca aacagcctat ttttcttgaa
     8941 aaaataggct ttttttctaa aaatccctag tcaagcgcct tattttt
//
LOCUS       DAVDHZ010000063         8854 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000063 DAVDHZ010000000
VERSION     DAVDHZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.064"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            66..299
                     /gene="secG"
                     /locus_tag="VUR46_002021"
     CDS             66..299
                     /gene="secG"
                     /locus_tag="VUR46_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET5457374.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            401..2755
                     /gene="rnr"
                     /locus_tag="VUR46_002022"
     CDS             401..2755
                     /gene="rnr"
                     /locus_tag="VUR46_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET5457375.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMCAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDEKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            2718..3185
                     /gene="smpB"
                     /locus_tag="VUR46_002023"
     CDS             2718..3185
                     /gene="smpB"
                     /locus_tag="VUR46_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET5457376.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            3201..4061
                     /gene="tehB"
                     /locus_tag="VUR46_002024"
     CDS             3201..4061
                     /gene="tehB"
                     /locus_tag="VUR46_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET5457377.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            4134..5087
                     /gene="coiA"
                     /locus_tag="VUR46_002025"
     CDS             4134..5087
                     /gene="coiA"
                     /locus_tag="VUR46_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET5457378.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            5106..6908
                     /gene="pepF"
                     /locus_tag="VUR46_002026"
     CDS             5106..6908
                     /gene="pepF"
                     /locus_tag="VUR46_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET5457379.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     GRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            6910..7623
                     /locus_tag="VUR46_002027"
     CDS             6910..7623
                     /locus_tag="VUR46_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET5457380.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            7690..8631
                     /gene="prsA"
                     /locus_tag="VUR46_002028"
     CDS             7690..8631
                     /gene="prsA"
                     /locus_tag="VUR46_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET5457381.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGSGDSSSSSSTSNE"
     gene            complement(8748..>8854)
                     /locus_tag="VUR46_002029"
     CDS             complement(8748..>8854)
                     /locus_tag="VUR46_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET5457382.1"
                     /translation="EQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         2851 a         1624 c         1948 g         2431 t
ORIGIN      
        1 taaccctaca tcttgaatct aagtagattt tatggtaaaa taatagggat tttaaggagt
       61 ttgatatgta taacctatta ttaaccattt tattagtatt atctgttgtg attgtgattg
      121 caattttcat gcaaccaacc aaaaaccaat ctagcaatgt atttgatgcc agttcaggtg
      181 atttgtttga acgcagtaaa gctcgcggtt ttgaagctgt aatgcagcgt ttgacaggga
      241 ttttagtctt tttctggcta gccattgcct tagcattgac ggtattatca agtagataag
      301 aaaataatgg gcaggactag gtctttgcct ctttttattt ttaaaggatg tttgagaagg
      361 ttttacagta aaagaaaatt aaaaaatcta gaaagaaaat atgaaagata gaataaaaga
      421 atatttacaa gacaagggaa aggtgactgt taatgatttg gctcaggctt tgggaaaaga
      481 cagttccaag gattttcgtg agttgattaa aaccttgtcc ttaatggaaa gaaagcacca
      541 gattcgcttt gaagaagatg gtagtctgac attagaaatt aagaaaaaac atgagattac
      601 cctcaagggg atttttcatg cccataaaaa tggctttggc tttgttagtc tggaaggcga
      661 ggaggacgac ctttttgtag ggaaaaatga tgtcaactat gctattgatg gtgataccgt
      721 cgaggtagtg attaagaaag tcgctgaccg caataaggga acagcagcag aagccaaaat
      781 tattgatatc ctagaacaca gtttgacaac agttgtcggg caaatcgttc tggatcagga
      841 aaagcctaag tatgctggct atattcgttc aaaaaatcag aaaatcagtc aaccgattta
      901 tgttaagaaa ccagccctaa aattagaagg aacagaagtt ctcaaagtct ttatcgataa
      961 atacccaagc aagaaacatg atttctttgt cgcgagtgtt ctcgatgtgg tgggacactc
     1021 aacggatgtc ggaattgatg ttcttgaggt cttggaatca atggacattg tatccgagtt
     1081 tccagaagct gttgttaagg aagcagaaag tgtgcctgat gctccgtctc aaaaggatat
     1141 ggaaggtcgt ctggatctaa gagatgaaat tacctttacc attgacggtg cggatgccaa
     1201 ggacttggac gatgcagtgc atatcaaggc tctgaaaaat ggtaatctgg agcttggggt
     1261 tcacatcgca gatgtttcct attatgtgac cgagggttct gcccttgaca aggaagccct
     1321 taaccgtgcg acttctgttt acgtgacaga ccgagtggtg ccaatgcttc cagaacgact
     1381 atcaaatggc atctgctctc tcaatcccca agttgaccgc ctgacccagt ctgctattat
     1441 ggagattgat aaacatggtc gtgtggtcaa ctataccatt acacaaacag ttatcaagac
     1501 cagttttcgt atgacctata gcgatgtcaa tgatatccta gctggcgatg aagaaaagag
     1561 aaaagaatat cataaaattg tatcaagtat cgaactcatg gccaagcttc atgaaacttt
     1621 agaaaacatg cgtgtgaaac gtggagctct caattttgat accaatgaag cgaagatttt
     1681 agtggataaa caaggtaagc ctgttgatat cgttcttcgg cagcgtggta ttgccgagcg
     1741 gatgattgag tcttttatgt tgatggctaa tgaaacagtt gccgaacatt tcagcaagtt
     1801 ggatttgcct tttatctatc gaattcacga ggagcctaag gctgaaaagg ttcagaagtt
     1861 tattgattat gcttcgagtt ttggcttgcg catttatggg actgccagtg agattagtca
     1921 ggaggcactt caagacatca tgtgtgctgt tgagggagaa ccttatgcag atgtattgtc
     1981 catgatgctt cttcgctcta tgcagcaggc tcgttattcg gagcacaatc acggccacta
     2041 tggactagct gctgactatt atactcactt taccagtcca attcgtcgtt atccagacct
     2101 tcttgttcac cgtatgattc gggattacgg tcgttctaag gaaatagcag agcattttga
     2161 acaagtgatt ccagagattg cgacccagtc ttccaaccgt gaacgtcgtg ccatagaagc
     2221 tgagcgtgaa gtcgaagcca tgaaaaaggc tgagtatatg gaagaatacg tgggtgaaga
     2281 gtatgatgca gttgtatcaa gtattgtcaa attcggtctc tttgtcgaat tgccaaacac
     2341 agttgaaggc ttgattcaca tcactaatct acctgaattt tatcatttca atgagcgtga
     2401 tttgactctt cgtggagaaa aatcaggtat cactttccga gtgggtcagc agatccgtat
     2461 ccgtgttgaa agagcggata aaatgactgg agagattgat ttttcattcg tacctagtga
     2521 gtttgatgtg attgaaaaag gcttgaaaca gtctagtcgt agtggcagag ggcgtggttc
     2581 aaatcgtcgt tcggataaga aggaagacaa gagaaaatta ggacgctcaa atgataagcg
     2641 taagcattca caaaaagacg agaagaaaaa aggaaagaaa cctttttaca aggaagtagc
     2701 taagaaagga gccaagcatg gcaaagggcg agggaaaggt cgtcgcacaa aataaaaagg
     2761 cacgccacga ctatacaatc gtagatacgc tagaggcagg gatggtcctg actggaactg
     2821 aaatcaagag tgtacgagct gctcgaatta atctcaagga tggctttgct caagtgaaaa
     2881 atggagaagt ttggctgagc aatgttcata tcgcgcctta cgaagagggc aatatctgga
     2941 accaggaacc agaacgtcgt cgtaaactcc tgctccataa aaagcaaatt caaaaattgg
     3001 aacaagagac caaagggaca ggaatgacct tagttcccct taaggtctat ataaaagatg
     3061 gctacgctaa gcttctttta ggacttgcca aagggaagca tgactatgac aaacgggagt
     3121 ctatcaaacg tcgtgagcaa aatcgagata tcgcgcgtgt gatgaaagct gttaatcagc
     3181 gataaaaaga ggaattgaaa atggaaaaat tagttgccta taaacgcatg cctttgtgga
     3241 ataaacaaac aatgcctgaa gctgttcagc aaaagcacaa tacaaaagtt gggacttggg
     3301 ggaaaattac tgtcttgaag ggagctctca agtttattga attgacagaa gaaggggaag
     3361 ttctagctga acacctcttt gaagcagggg cagacaatcc aatggcccaa cctcaagcct
     3421 ggcaccgagt ggaagctgcc acagatgatg tggaatggta cttggaattt tattgtaaac
     3481 ctgaggatta ttttgctaaa aaatacaata ccaatcctgt tcattcagag gtcctagagg
     3541 ccatgcagac agtgaaacaa gggaaagctt tggatttggg ttgtggtcag gggcgtaatt
     3601 ctctttttct agcccagcaa gattttgatg tgacggctgt agatcaaaat ggactagctc
     3661 ttgaaatctt gcaaagcatt gtggagcagg aagatttgga catgcctgtt ggcctttacg
     3721 atatcaattc agctagcatt gaacaagaat atgattttat cgtttcaaca gttgttctca
     3781 tgtttctaca agcggaccgc attccagcta ttattcaaaa tatgcaggag aaaaccagtg
     3841 ttggtggtta caaccttatc gtttgtgcca tggacacgga ggattatcct tgctcggtta
     3901 acttcccatt cacctttaaa gaaggagaac tggcagacta ttacaaggat tgggaattgg
     3961 ttaagtacaa tgaaaatcca ggccatttgc accgtcgcga tgagaatggc aatcgtattc
     4021 aactacgctt tgcgacctta ctagctaaga aaatcaagta aacacacatg aagattagga
     4081 attttcctga tcttttttct tttttacgaa tgatatagaa aaggagggaa ttcatgtttg
     4141 ttgcgagaga tgctagggga gaattggtaa atgtgttaga ggataaactt gagaagcaag
     4201 catacacctg cccagcttgt ggaggccagc tccatttgcg tcaaggacca agtgtacgga
     4261 cgcattttgc ccataaatcc ttaaaagact gtgatttttt ctttgaaaat gaaagtccag
     4321 aacacctggc caataaggaa tccctctatc actggttgaa aaaagagaca aaggttcaat
     4381 tagagtaccc gctttcagaa cttaaacaga ttgcggatgt atttgtaaat ggcaatctag
     4441 ctctagaagt tcagtgtagt cccttgcctc agaaagtcct taaagagcga agtgagggct
     4501 atcgtagtca gggttaccaa gtactgtggt tgctgggtca aaaactgtgg ctcaaggagc
     4561 gtttgactcg tctacagcaa ggttttcttt atttcagtca aaacatgggc ttttatgttt
     4621 gggaattaga caaggaaaaa caagttttaa gactcaaata cctgatttac caggatctcc
     4681 gcggtaaact ccattatcaa atcaaggaat tttcctatgg tcaaggtagt ttattggaaa
     4741 tattgcgtct tccctataag agacaaaaaa tatctcattt tacagtttct gaggacaagg
     4801 acatctgtcg ctatatccgg caacaacttt attatcaaaa tctcttttgg atgaaagaac
     4861 aagcagaagc ctatcaaaag ggagaaaata tcctgactta tggactgaaa gaatggtatc
     4921 cacaaattcg accaatagtg ggcaaatttt tccagattga acaagacttg actagctatt
     4981 atcagcactt ttatacctat taccaaaaaa atcctcaaaa tgattggcaa aagctttatc
     5041 caccagcctt ttatcagcaa tatttcttga aaaatatggt agaatagaaa ggatggagga
     5101 atctaatggt attacaaaga aatgaaataa atgaaaaaga tacatgggat ctatcaacga
     5161 tctacccaac tgaccaggct tgggaagaag ccttaaaaga tttaacagaa caattggaga
     5221 cagtagccca gtatgaaggc catctcttgg atagtgcgga taacctacta gaaatcactg
     5281 aattttctct tgaaatggaa cgccagatgg agaagcttta cgtttatgct catatgaaga
     5341 atgaccagga tacacgtgaa gctaagtatc aagagtacta tgccaaggcc atgacactct
     5401 acagccagtt agaccaagcc ttttcattct atgagcctga atttatggag attagcgaaa
     5461 agcagtatgc tgacttttta gaagctcaac caaagctgca ggtttatcaa cactattttg
     5521 acaagctctt gcaaggcaag gatcacgttc tctcacaacg tgaagaagaa ttattggctg
     5581 gagctggaga aatctttggt tcagcaagtg aaaccttcgc tatcttggac aatgcggata
     5641 ttgtgttccc ttatgtccta gacgatgatg gtaaagaagt tcagctatct catgggattt
     5701 acacacgttt gatggagtct aaaaaacgtg aggttcgccg tggtgcctat caagctcttt
     5761 atgcgactta cgaacaattc caacacacct atgccaaaac cttgcaaacc aatgttaagg
     5821 tgcaaaatta ccgtgctaaa gttcgtaact acaagagtgc tcgtcatgca gccctcgcag
     5881 cgaattttgt tccagaaagt gtttatgaca atttggtagc agcagttcgc aagcatttgc
     5941 cactcttaca tcgctatctt gagcttcgtt caaaaatctt ggggatttca gatctcaaga
     6001 tgtacgatgt ctacacaccg ctttcatctg ttgaatacag ttttacctac caagaagcct
     6061 tgaaaaaagc agaagatgct ttggtagtct tgggtgagga ttacttgggc cgtgttaaac
     6121 gtgccttcag cgagcgttgg attgatgttt acgaaaatca aggcaagcgt tcaggtgcct
     6181 actctggtgg ttcttacgat accaatgcct ttatgcttct caactggcag gacaatctgg
     6241 acaatctctt tactcttgtt catgaaacag gtcacagtat gcattcaagc tatactcgtg
     6301 aaactcagcc ttatgtttac ggagattact ctatcttttt ggctgagatt gcctcaacta
     6361 ccaatgaaaa tatcttgacg gagaaattat tggaagaagt ggaagacgac gcaacacgct
     6421 ttgctattct caataacttc ctagatggtt tccgtggaac agttttccgc caaactcaat
     6481 ttgctgagtt tgaacacgcc attcaccaag cagatcaaaa tggggaggtc ttgacaagcg
     6541 atttcctaaa taaactctac gcagacttga accaagagta ttatggtttg agtaaggaag
     6601 acaatcctga aatccaatac gagtgggctc gcattccaca cttctactat aactactatg
     6661 tatatcaata ttcaactggc tttgcggccg cctcagcctt ggctgaaaaa attgtccatg
     6721 gtagtcaaga agaccgtgac cgctatatcg actacctcaa ggcaggtaag tcggactatc
     6781 cacttaatgt catgagaaaa gctggtgttg atatggagaa ggaagactac ctcaacgatg
     6841 cctttgcagt ctttgaacgc cgtttaaatg agtttgaagc ccttgttgaa aaattaggat
     6901 tggcataaaa tggttgaatc gtatagtaag aatgctaacc ataacatgcg tcgtcctgtc
     6961 gtcaaagaag aaattgtaga cttgatgcgt cagcgtcaaa agcaagtcac aggtttcttg
     7021 aaagaattgg aagattttgc ccgcaaggaa aatattccta ttattcccca tgaaacggtt
     7081 gcttatttcc gttttcttat ggaaaccatg cagcctaaaa atattctgga aattgggacg
     7141 gctatcggtt tttcagctct cttgatggct gaacatgcgc caaatgctaa gattacaact
     7201 attgatcgta atccagaaat gattggtttt gccaaggaaa attttgccca gtttgacagt
     7261 cgcaagcaaa tcactctcct agagggagat gcggtggatg tcttatctac actgacagag
     7321 tcttatgatt tcgtctttat ggattctgcc aagtctaaat acatcgtctt tctgccagaa
     7381 atcctcaaac atttggaagt tggtggtgtg gttgtcttgg atgatatttt tcaaggtggt
     7441 gatgttgcca aggatattat ggaagtccgt cgtggtcagc gaaccattta tcgaggcctt
     7501 caaaaattat ttgatgcaac cttagacaat ccagaactca ccgcaacatt agtgccttta
     7561 ggagatggta ttctcatgct tcgtaaaaat gtagcagatg ttcaactgtc tgaaagcgaa
     7621 tgattttcag aaaaatttaa gaaaaaatag taaaatagat agagtaacac ttatctcaaa
     7681 ggagtagaca tgaagaaaaa attattggca ggtgccatca cactattatc agtagcaact
     7741 ttagcagctt gttcgaaagg gtcagaaggg gcagacctta tcagcatgaa aggggatgtc
     7801 atcacagaac atcaatttta tgagcaagtg aaaaacaacc cttcagccca acaagtcttg
     7861 ttaaatatga ccatccaaaa agtttttgaa aaacaatatg gctcagagct tgatgataaa
     7921 gaggttgatg atactattgc cgaagaaaaa aaacaatatg gcgaaaacta ccaacgtgtc
     7981 ttgtcacaag caggtatgac tcttgaaaca cgtaaagctc aaattcgtac aagtaaatta
     8041 gttgagttgg cagttaagaa ggtagcagaa gctgaattga cagatgaagc ctataagaaa
     8101 gcctttgatg agtacactcc agatgtaacg gctcaaatca tccgtcttaa taatgaagat
     8161 aaggccaaag aagttctcga aaaagccaag gcagaaggtg ctgattttgc tcaattagcc
     8221 aaagataatt caactgatga aaaaacaaaa gaaaatggtg gagaaattac ctttgattct
     8281 gcttcaacag aagtacctga gcaagtcaaa aaagccgctt tcgctttaga tgtggatggt
     8341 gtttctgatg tgattacagc aactggcaca caagcctaca gtagccaata ttacattgta
     8401 aaactcacta agaaaacaga aaaatcatct aatattgatg actacaaaga aaaattaaaa
     8461 actgttatct tgactcaaaa acaaaatgat tcaacatttg ttcaaagcat tatcggaaaa
     8521 gaattgcaag cagccaatat caaggttaag gaccaagcct tccaaaatat ctttacccaa
     8581 tatatcggta gtggagattc aagctcaagc agtagtacat caaacgaata gtccaaatca
     8641 atgagtcagg gaaaaaactc gacttcagga aaaaatgaag caaacattcc cacaataaaa
     8701 cgcatagtac aaggtttgta ctgcccccaa aaagttagac aattaattta tccgaaggac
     8761 ttagttctgt attgcacagg gctaagtcct tttagtttta ccttaattct cttattgttg
     8821 taataatcaa tatagtctat aatggcttgt tcca
//
LOCUS       DAVDHZ010000064         8750 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000064 DAVDHZ010000000
VERSION     DAVDHZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.065"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(65..856)
                     /locus_tag="VUR46_002030"
     CDS             complement(65..856)
                     /locus_tag="VUR46_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET5457383.1"
                     /translation="MYQKLLRKIAEEKPSYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFYFIAEGISSDGGLDKDIDKVGLSTLERSFRALIYVNLLSADANQ
                     QSIFYQRLKSEIRNVLLNQGLYYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPN
                     FPKTRVHEVFDILGQLFKRITIRFTDDEDWRLARVLYEPILQGKLEQEQVASWIKIVD
                     FPIEEREDFYKFSNFRSCLSEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            complement(1281..2045)
                     /locus_tag="VUR46_002031"
     CDS             complement(1281..2045)
                     /locus_tag="VUR46_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5457384.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIAPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWSGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(2038..2724)
                     /locus_tag="VUR46_002032"
     CDS             complement(2038..2724)
                     /locus_tag="VUR46_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457385.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GKNIETNRRKSKSCLGIVGQEDMLDMTLNVYDNLFAHGLCYGISSVELRKRIGSLLDF
                     VQLSKHAQKMVNQLSGGMRRRLVLARALINRPDIIILDEPTVGLDIQSRNIIWDKLLE
                     LKELGVSIIITSHYMNEIEYLTDRVLMLHQGTIKEEGTVEDLLIKYDADNLETLFLGL
                     TGTEKEDLHV"
     gene            complement(2694..3806)
                     /locus_tag="VUR46_002033"
     CDS             complement(2694..3806)
                     /locus_tag="VUR46_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET5457386.1"
                     /translation="MNLPKIKDIHSVLFLKDKIRLGIGKDYGIEIENLDEKYTQLIKL
                     LDGQYTINEICSLVDSLSPNEVEESISLLDTLGYLEDNFVTTTELTSEELDRYSVNLN
                     FFNTLDTLSLTKYDYQLKLKKTRILLLGIGGIGSNICLALAELGIGHITAVDFDTVEA
                     SNLNRQILYSTSDIGKRKVEAAKESLRKFNPLIEFEVLDKEIGSKEDVDELIKTSKCD
                     IVVNVADYPTGYIDFWVNEACVQYNKLCLSAVVGKKNGKVYSIIPYKAACYYCQFLED
                     LEKIPEYAEELETVRTMTNSLELEMFRTPNGALGPACLFQGYFISFEILRYIFWGYEA
                     LLTFNKRFSIDFITFEQHFDELTKYPTCSICGGKKE"
     gene            4074..4751
                     /locus_tag="VUR46_002034"
     CDS             4074..4751
                     /locus_tag="VUR46_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5457387.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
     gene            complement(4811..6607)
                     /gene="pepF"
                     /locus_tag="VUR46_002035"
     CDS             complement(4811..6607)
                     /gene="pepF"
                     /locus_tag="VUR46_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET5457388.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALANLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAQYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(6619..7362)
                     /locus_tag="VUR46_002036"
     CDS             complement(6619..7362)
                     /locus_tag="VUR46_002036"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET5457389.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(7364..8317)
                     /locus_tag="VUR46_002037"
     CDS             complement(7364..8317)
                     /locus_tag="VUR46_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET5457390.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQARLAELTDFMDLGEVKMGTTAL
                     AEEDWADNWKKYYAPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNT
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            complement(8452..>8750)
                     /locus_tag="VUR46_002038"
     CDS             complement(8452..>8750)
                     /locus_tag="VUR46_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5457391.1"
                     /translation="REGDESPFECAAREVYEELGIHLTEDCLLWSKVYPSMLFADKQS
                     VFLVGQLTQNQFDSIVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
BASE COUNT         2704 a         1981 c         1511 g         2554 t
ORIGIN      
        1 gggaaagggt ttcaagaaaa ttgattggaa attttttgaa aatcatagag ctattagctt
       61 atccctagta ttgaaaagac tggatagctt ctttcaagtc atcttgtaaa ctatttctct
      121 ggtcgagttg tacatagact tctgagagac aggatctgaa attggaaaat ttgtaaaaat
      181 cttccctttc ttctatcgga aaatcaacaa tttttatcca agaagctact tgctcttgct
      241 ccaacttccc ttgtaaaatc ggttcataaa gcactctggc taaacgccaa tcttcatcat
      301 ctgtaaaacg aatggtaatt cttttaaata attgaccaag tatgtcaaat acttcatgaa
      361 ctctggtttt aggaaagttt ggatgacaaa ccacctctgt cagtaaatcg gctccatgtg
      421 caaaagcatg aacccaacca tactgacttg aaaaacccct tgtatccttt tcttttgaaa
      481 gataatacaa gccttgattt aaaaggacat tgcgaatctc tgattttaat ctctgataga
      541 aaatcgattg ctggttggca tcagcagaca agagatttac ataaataagc gccctaaaag
      601 aacgttcaag tgttgacaag cctaccttat caatatcttt atctaaccct ccatcagatg
      661 aaatcccttc agcaatgaaa taaaattgtt cctgtgtaaa tagctcttcc tgaatccctc
      721 tagcaaagct tgtaaaaaca aggtcatcac gaatttctgg agaaggatct cccaaatgat
      781 caagtagcca ctggatttct tcctggttat aacttggttt ttcttctgct atttttctaa
      841 gtaacttttg atacatggtc aatacctcta catttctagc aactgttcaa aaagctgtcc
      901 ttaaatgact ttagcaattt gtaaaattaa gttaaagaga aaaagacatt tatattcaga
      961 gaaacagcac atttctgaaa ggatacataa atgatttatt ccatattacc acaaatgaac
     1021 ttgtaatgat agaactttat cacaaaaatc acattcctgt ctcaaaaatt gcgaaaaact
     1081 agttataata aagtgaaata aaaactatac aaattgatta gggaatttaa aacaatttct
     1141 aacaatattt taaaaactga accgtactat ttcaacttcc ataaattaca atattgatag
     1201 gcacagttcc catacctatc caaattcgaa taacgtttag tataaattag aatatgacta
     1261 caacatcaca aataattaga ctatctataa tatctacgat gtaacatata cataggaagc
     1321 accgttatca agagcgccaa ggctatcaac cagataagat gaagatacaa acctgtcacc
     1381 tcacctcccc atataatacg aatcatgcgg gtagcgtgat acaagggaga aaaccaagtc
     1441 aaatcaccaa gtattggggg caaggaagta atgggaaaga aggtatctga aaacatataa
     1501 agaggacgga ttaccaaaac attgtagtaa ttcagaaatt ccctagacgg cgccaagtag
     1561 gtaaagatta gtcccaaaac accaaacaaa taacccacta taaataaaat cagaggaatc
     1621 aataacatca agacatgaaa atgcgctgtg ataagcatgg aaatcagcca aaaaatccca
     1681 ccgaaaatca ctgcacgaat acctgaccag atagcctgac ccaccacaat atcattcgta
     1741 ttgattggcg tcatcaacat agcatcataa gtcttttcaa tcttatactg gataaaggca
     1801 ttgaccgttg tttctgcggt ggccgcagac atggcagtcg cagcaattaa acctgtaatg
     1861 acaaaatcac ggtagagcat accgttaaca tgcgtcaaat aagcaccaac tccaaatccc
     1921 attgctaaaa gataaaagag gggggcgata aggttgggga caattgaaat tttaaataaa
     1981 tttctaaaac tcatgtagtt gcgtaccaca acgtgtccga tggagtgaaa tgataactta
     2041 aacatgcaag tcctccttct ctgtcccagt caaccccaaa aaaagtgtct caaggttgtc
     2101 agcatcatac ttgatgagca agtcttctac agttccttct tctttgatag tcccttggtg
     2161 gagcatcagc accctatctg tcaaatattc aatctcattc atatagtggg aagtaataat
     2221 gatggaaaca cctaattcct tcaactccaa aagtttatcc caaataatat tgcgggattg
     2281 aatgtctaaa ccaactgtcg gttcatctaa aataataata tcaggccgat tgatgagagc
     2341 tcttgccaag acaagacgtc gtcgcatccc acccgacagc tgattcacca tcttttgcgc
     2401 atgtttgctc agttgaacaa aatccaagag agaaccgatt ctcttcctaa gttcgacaga
     2461 tgagatacca taacatagac cgtgagcaaa aagattatca taaacattca aggtcatgtc
     2521 cagcatatcc tcctgcccta caatacccag acaagattta ctcttacgac gattggtttc
     2581 aatatttttc cccaagatac ccaaacactc tccttctccc aattcaaagc taattccctt
     2641 gacagcttca taagaaccat attgcttttt tagattttta acacttaact tcttcactct
     2701 ttctttcccc cacaaataga gcatgttgga tactttgtta attcatcaaa atgttgttcg
     2761 aatgttataa agtcaattga gaatctttta ttaaatgtta gcaatgcttc gtatccccaa
     2821 aaaatatatc ttaaaatttc aaacgaaata aaataccctt gaaatagaca agcaggacct
     2881 aaagcaccat tcggagttct gaacatctct agttccaatg aatttgtcat tgtacgaacg
     2941 gtctccaact cttcagcata ctcaggaatt ttttccaaat cctctaaaaa ctgacagtaa
     3001 tagcacgctg ctttatacgg aataattgaa tatactttcc catttttctt accaaccaca
     3061 gcagacagac ataatttatt gtattgaaca caggcttcat tgacccaaaa atcaatatag
     3121 cctgttggat aatctgcaac atttactacg atatcacatt ttgaagtttt tattaactca
     3181 tcgacatcct cttttgaacc tatctcttta tcaagtacct caaattcaat taaaggatta
     3241 aactttctaa gcgactcttt tgcagcctct acttttcttt ttccaatatc agatgtcgaa
     3301 tacaaaattt gtctattgag attactagct tcgaccgtat caaaatcaac tgctgtaata
     3361 tgccctatac ctaattcagc caatgctaga cagatattac ttcctatacc accaatacct
     3421 aagagcaaaa tacgcgtctt ttttaatttt aactgataat catactttgt taaagataat
     3481 gtatctaaag tattaaaaaa gttaagattt acggaatatc tatccaattc ttctgaagtt
     3541 aattcagttg tagtaacaaa attatcctcc aaatacccta gtgtatctag taaagaaata
     3601 ctttcttcta cctcattagg ggacaagcta tcaactaagc tacaaatttc attgattgtg
     3661 tattgtccat cgagaagctt aatgagctga gtatacttct catccagatt ctcaatctca
     3721 ataccataat cttttcctat acctaatcta attttatcct ttaaaaatag gacactatga
     3781 atatctttaa ttttaggtaa attcaattct atttcctcct aaaatagaca aaaagaatgg
     3841 aaaaatccat tcacttttga aaaaatgttg agaatgtaat cttaagatta acgtccttca
     3901 actgtggata ctgctgcaat tacttttgta attttacctc catttaaact cagacaataa
     3961 aatttaaaat attctctagt aaaacatttt taaaatctat ttttcttgtg ctttaattat
     4021 agtataataa aagatagaaa atcatcgata tatgaaattt ggagaaaatt tttatggaac
     4081 cagatatttt catcatcaca aaactcttat cagacccttc tcggatgcac attttagata
     4141 ttctaatgga tggaaaagct cacacggtta acgaaattgc cagctttacc aaaatcaagc
     4201 aacatactgt cagctatcac ctcaaattac ttaccgaagc gcaggtaacc actctacaaa
     4261 cctatggacg ttttcattat tattctttaa aaagtgctgc cattgcagaa atgctggaat
     4321 ttctcagctt ctactctcct cagcgtgatg tcaaaagtta taaacaacac attcacaaaa
     4381 aggaattaaa agtcgctcgc acctgctatg accatattgc tggtgagctt ggcatttcca
     4441 ttaccaatta tctcttgcaa gaaaatctcc tcagcgaatc agaaaaagac ttccaactca
     4501 ctgaagctgg gaagtcttat ttccaaagaa aattacacat tgatacggat gaattgaaaa
     4561 agaaaaaacg gaaattttgc cctaaatgtt tggattggag cgaacgtaaa aatcatgtcg
     4621 gcggagctct cggcaatgct cttttagaat ttttcagtga aaaacaattg gtcatccctg
     4681 cacaaacgcc acgttcactt accattacag agcagggcaa agaattcctc gaaaaggaat
     4741 gggggattta aacatggaat tttaagcaaa taactgtcca tacccattct ataacaacct
     4801 ctctatcccc ttactccccc aactcagcac tgtaggcgat aatctggtca actgtgtcag
     4861 acaagaattg gatggtatca cggagtggtt tgtctgttga aatatcagca ccgataatca
     4921 tggctgactc aagtggtgtc ttgctaccac ctgatttaag gagattgagc cagtcttcag
     4981 ctccagtttc tgagttttta agatgaaggt aaccagcagt cgagataact agtcctgctg
     5041 agtaagtgta actatacaag cccatatagt attgagcttg gcgcatccaa gtcaaagctg
     5101 catcgtcgtc gatttcaatg gcatcgcccc aaaaatctgt caaaacttcc ttcataatgc
     5161 tgttgagttt gcttgctccg aaggtttctc cttcttcaat caatgtatac accttacgct
     5221 ggaaggctgc ttccaagagg tgggtgataa agttatggaa gtaggtgtct gtcaagcgat
     5281 gagccagagc gaagcgtttt tgacgtgggt cattagactg gttctctaag taatcactga
     5341 gtagcaattc attgaaggtc gacggtgctt caacataata ggtcgacatg tgggcgttga
     5401 aatagctttg gtgattgtct gaaaagatga attgaccaga atgcccgatt tcatgaatca
     5461 aggtatagac atcgctcaaa cggcctgtcc agctcatgag gacataaggg tgtacgcgat
     5521 atgggtccgc cgcataacca ccggaatcct tgccactgtt agcagcaaag tccacccagc
     5581 gctcttcttg gtaacgagca acttcctgac aatattcttg ccccaaaggt tctaccgact
     5641 tcatgaccaa atcataggca tcgtcaatag tcacttcagg attcagggcg ctgtccaagt
     5701 ccaatttcca gtctgcaaag gtcatctttt caagaccatt taccttggca acatgcttga
     5761 ggtatctctg agcgactggt gcaaagtcct tcatgatgag gtcaatctgg cgatcaaaca
     5821 tgacacggtc cacttcttgt tcagctagaa gataatcaaa gacagagtcg tatcccttca
     5881 tatcagccaa gagtttttca gacttgacct gagccagata ggctgctgca gccgtatttt
     5941 ggtgcttacg aagtccctct gagaaggaac ggaaggattt ctcacgaacc tcagcatcct
     6001 cgtgattttg gtagaaattc tcataggtga caaagctgtt tttgtaggtc ttgccatggg
     6061 cttcaaagtc agccatttca aaatccccag ctcgcatctt agtataaatg tcctgcggac
     6121 tatagaaaac ttcaccgaga ttggctaagg ccttctccac atcagcccct agatagtggg
     6181 cttttttgat tttggcctga cgaatagctg ccgtcaagtg aggcaattca cccaaacggt
     6241 ccaagacttc ctcgtctgct accaccaagg catcgtcaaa gaaggtcaag gctacgctgg
     6301 catctgtttc aaattccatc ccagcttggg caatattggc aaattcgtca ttgctatagt
     6361 ccgtcgtctg aggcataaaa ccatagttgc caatatggct catctgaatg tagatctgtt
     6421 ccaattccgc aaaggccttc tcgaaatcct caaaagtgtg aagattgccc ttgtaatcac
     6481 ggctaaactg gttgatgtct tcgcgagctt tctcgattgc acgcaagaaa tcctcacggt
     6541 cttggtatag ggctgttaag tcccagagtt ccttctctgg aaattctgaa cggtgttttt
     6601 gttccatttt cttcctcttt atttctctaa ttctactaaa acactaaggg ctgataaagc
     6661 gtaaagcggt gctgtttctg ctcttagaat gcgagggcca agtcctgcca aaacagctcc
     6721 cttagcttca aaattttcaa tttccgcagg tgacagacca ccttctggac caaagataaa
     6781 gagcagtttg gctcctgttt caagaccagt gactgcttgc agaagcgcag cggcttctcc
     6841 ttctttagct gattcttcat aggctactat gatagagtca aactggtcca gctgagctag
     6901 aaaatctgct tttttctcga aaagtttaat acttggtaca atattacgct tgctttgctc
     6961 ggctgctcca agggcaattt tttctagttt ttcaactttt ttacccaatt tcttgccatc
     7021 ccacttggca actgaccagt ctgcaggaaa ggcccagatt tggctagcac ccagttcggt
     7081 tactttttga gcgatgaact ccagcttgtc tcccttggga aatccagatg cgatggtcac
     7141 ttggactggt agttccacat tgtcatttaa ttcttggacc aactcaaact gacgattttc
     7201 catatccagc acgcgcgcca agcgcttgat gccatcatca aagactaagg taacctcatc
     7261 ctcttctttc aagcgcataa cctgaaacat atgcttactg gtttccttgt cctcgatagt
     7321 gacaggagaa atagcactgc cttttacaaa atactgctgc atgctagcct ccaatcacac
     7381 cagagatatc cttggttttc ttaaagacac aggtattcca ttccccttga accatgtgag
     7441 tttcgaggaa aaatccagct gattcagccg actcgcgcac catgtcccac ttatccttga
     7501 taatgccact catgatgagg tagccttcat cctttaccaa gcgataagca tcctccgtca
     7561 gatgaatgag aatatccgcc aagatattag ccacgatgac atctgcttca atctcaactc
     7621 ccttaagcaa gtctcctgct gctacatgga tattttccat accagtgttg agctcaatat
     7681 tttcctgagc gacacgaacc gccacatcat ccaagtcata ggcgaaaatc tccttggcac
     7741 ctaggagtga gcttgcaata gaaagaaccc ctgaaccagt ccctacatct agcactgttt
     7801 cgccaccacg aagaacctgt tccaaggcaa agaggctcat cttggttgtt gggtgggtcc
     7861 ctgtcccaaa ggccatacca ggatccagct tgataatctt ttctcctgct gttgcctcat
     7921 agtccgtcca tgacggtacg atggtcaggt catgggtgat gcgtgccggt gcataatact
     7981 tcttccagtt gtcagcccag tcttcctcag ccaaggcagt cgtgcccatc ttgacttctc
     8041 ctaggtccat aaagtcggtc aattctgcca gacgagcctg caaatccgct tcaactgctg
     8101 ctacatcaac cgtttcaggg tagtaggctg tcactacgat ttcttcttgc tgctccacct
     8161 ctgggaaaat ctcgccgaag cggtccacat ttcccacata gtccatactg tcttcgattg
     8221 cgactccttg cgctcccagc tcaatcaaga gattggaaac caattcctcc ccctcacgct
     8281 tcactgtaac ttttaactct tgccatgttt ccatcattaa gataccaagc ccgtaaaaca
     8341 caaaaccaaa ataggaaatt ctctgaagac gcttgtgtct aagagaagtt tatctttttg
     8401 gcacagtgtt tagggcgggt tcagtttaga aatttaactg aaccatcctt tctaatcact
     8461 tacttttaaa taatctttta atctctcttg caactgaggc acaacttgac tggaactaag
     8521 aaattcctca acattcatca gctgatagcc ctgtccttca tctccaaata cgatactgtc
     8581 aaactggttc tgtgtcaact gaccaactag aaaaacggac tgtttatctg caaaaagcat
     8641 acttgggtaa accttactcc aaagcagaca atcttcagtc agatgaatgc ccagttcttc
     8701 ataaacttca cgcgctgcgc actcaaaagg actttcatca ccttcacgtc
//
LOCUS       DAVDHZ010000065         8693 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000065 DAVDHZ010000000
VERSION     DAVDHZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.066"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(100..582)
                     /gene="greA"
                     /locus_tag="VUR46_002039"
     CDS             complement(100..582)
                     /gene="greA"
                     /locus_tag="VUR46_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET5457392.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRQEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVIIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVDSYDVKILKVEKTA
                     "
     gene            complement(653..2308)
                     /gene="mltG"
                     /locus_tag="VUR46_002040"
     CDS             complement(653..2308)
                     /gene="mltG"
                     /locus_tag="VUR46_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET5457393.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPRPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVTSFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRNR
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2389..2883)
                     /locus_tag="VUR46_002041"
     CDS             complement(2389..2883)
                     /locus_tag="VUR46_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457394.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2880..3344)
                     /locus_tag="VUR46_002042"
     CDS             complement(2880..3344)
                     /locus_tag="VUR46_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457395.1"
                     /translation="MEIPIKIIQASKSDLPEIEALQTSSFPAEKQQPSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEDATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3354..4688)
                     /locus_tag="VUR46_002043"
     CDS             complement(3354..4688)
                     /locus_tag="VUR46_002043"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET5457396.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADKNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLKDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFESEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFVHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4700..5317)
                     /locus_tag="VUR46_002044"
     CDS             complement(4700..5317)
                     /locus_tag="VUR46_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET5457397.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5365..8463)
                     /locus_tag="VUR46_002045"
     CDS             complement(5365..8463)
                     /locus_tag="VUR46_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5457398.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSGCAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPTLFMEDYQ
                     GVSGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8556..>8693)
                     /locus_tag="VUR46_002046"
     CDS             complement(8556..>8693)
                     /locus_tag="VUR46_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457399.1"
                     /translation="EAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAK
                     C"
BASE COUNT         2373 a         1981 c         1663 g         2676 t
ORIGIN      
        1 tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtagca aaacagaaaa
       61 aggagtgagt gaagcgcatc gccactcctt tttctgtttt taggctgttt tttcaacctt
      121 caagattttt acatcatagc tatcaacagg cgtttcaatg gttgctgtgt cacctgtttt
      181 cttgccaatc aaggcctgcc caattgggct ttcatttgaa accttacctg caaaggcatc
      241 cgcaccagct gaacctacga taatataaac ttcttcttcg tcctcaccaa tttcttggat
      301 gatgactgtt ttaccaatcg ctacttcgtc ctgggcaact gcgtcgctat tgacgatttc
      361 agcatagcgg atttttgttt ctaagctaga gatttgtcct tcgacaaagg cttgttcatc
      421 cttagctgct tcgtactcac tgttttctga aaggtcaccg tatgaacggg caatcttaat
      481 gcgttctacc acttcttgtc gacgaaccaa tttcaattct tctaattctt tttcaagttt
      541 ttccttttcc tcaagggtca taggatatgt tttttctgcc atttttctca actttcttct
      601 gataatattt tctaaagaaa attatgtgaa gtatcacata attttagttt gtttagttta
      661 atttgctgtt gacatgttca gcgacattgc ggtcgtggtc ttcttgattg ttagcatagt
      721 agaccttgcc ttctgtgaca tctgctacaa agtagaggtt atcgctctta gtttgattga
      781 tgcttgactc aatcgcatcc agacttggac tatcgactgg accaggcatg agacctacat
      841 ttttataaac attataaggt gaatcaatgt tggtatcaat cgcaacatcc tcagctagac
      901 tgatattttg ccccagtttt ccttgggcat acaagattgc aatattactt tgaagtggcc
      961 tattacgatt caaacgattg tagaatacac ctgcaatgag cttacgatct tctgtcttgg
     1021 caccttcttt ttcgaccaag gaagcaatgg tcaacaactc attgacagtc aagtttttag
     1081 atttgatagt actatagtaa ggagataggt tcttatccat agcagctaac atctcatcaa
     1141 tcaagctctc aatagttgtg ctttccttga tagagtatgt agctgggaaa aggtatcctt
     1201 ccaaacgata acgcgcaccg ctgtctttta caggcaaact ttccagtaaa gtaggatatt
     1261 tagctactgc ttgactgata aacgtctcat cttgaacttt agccaagaaa gtctccgctg
     1321 tcaaagactc tttgaagtca ccttgcaatt gacccacagc ttgagcaatc tgatccaagg
     1381 tataaccttc tggaattgtc aaagtcgcaa gtacaggttc ttgcggttca tctgttccac
     1441 ctttttgcaa ctctttgagt aagtcttctg tactcatact cttttgcaaa ttgtagtaac
     1501 ctgctttcaa gtcggtataa tttttatact tggcataaaa actaaaaatc agaccatgct
     1561 ttaccaaacc agctttttca agcgtcgtac cgatttcttg aacgtttgaa ccttctggaa
     1621 ttccaaccgt cacatatttc ttagaattag catcgatagg taacaaagaa tctagcacgt
     1681 actggtaacc aaagtaacca cctgctgaga gcaaggcaag gaatacaagg aatgaagtca
     1741 caaaagcttt cacatgtgac ttcttctctt tcttaggctt aacgggtttt gctccttctc
     1801 tacggctacg acgtgatgta tcgctgatga tatccactgt ttctgtagca ggcctaggtg
     1861 tttctggacc tgcttgttct gcttttttct ctgccgtcgt ataggaaaca gctacccttg
     1921 ttggggtttc attgtattct ctttcaagtt tcttaggtct aacaggacct ggacctggtc
     1981 ttgatccact ttcttccgct ggagaagaag gtacatcttg acttggatga cttggaacac
     2041 caggagtttc tctttgaatc tcatctgctg gagaagctgg tacaccttga cttgggtgag
     2101 taggcacggt aggagctttt ctcataatct cctctaccgt tgacaaggaa tcagccatga
     2161 gttcctcagc tgaaggttca tttgcaggag tgcgaactac tgcctcatct tctttcagaa
     2221 cttcatcata gccttttact ttttctaaat ctctcagaat ctgctcttta aagcttaatt
     2281 tctcttcttc tcttgacttt tcactcaaaa gtttttcctc cttgttgata atccataata
     2341 ttatatctta aaagtcaaaa aaaagcaatc tatgatactt ttcctaactt attttttcat
     2401 ttcccagacc atatcatacc atgtttcccc tgcaaaggtt gactgggact ggccttcgtt
     2461 gacaaatcca tgtttttcat aataggcgat gagatagtca tgacaggtta gattaatgcc
     2521 atctctctca tcttcaagag caacttcttt caaggctgtc agcaatttct gacccagtcc
     2581 gagtccctgt gcctccttgg caatagacag acaggtcaca gagatataac caccaggctc
     2641 atgactatag tcttttattt cttctgtaaa agactggtct tgcagatggc ggtgcaggcc
     2701 aactggtcct tcgatataac ccatgattct tccttctttt tcagcaacca gaaaagaggt
     2761 ctgaatttct ctcaaatgtg cttcaaagac agaaggagga atggcttctt cgaccgaaaa
     2821 attttcaaat tcaagttcaa caatccgatc caaatcttct aatcttgctt gtctgatttt
     2881 cattgttcct ccagataaaa gggattaaac caaatcatac tatagccctg gctagttgca
     2941 tagagcaaag ttgcgtcttc atcaacaaaa ccgttcattt caaaatagga aagcagctca
     3001 tcaggactct ccaaacgaat ccctttgtaa tccagctcaa ctgccacctc tttcaaggct
     3061 gcaagaagaa gtgttcccaa gccctgtctc tgatggtcag actcgatgac taaagaatgt
     3121 acttttagat attgcggatt gtctgactgg ggacttgata aaatatagcc taaaagttga
     3181 ttttcatccc tagctagaag aaaggtatcc gcacacttac ggatactttc ttctaaaata
     3241 tgggaaggtt gctgcttttc agctggaaaa gacgaggtct gaagtgcctc tatctcaggc
     3301 aaatcagact tgcttgcctg aatgatctta attggaattt ccatgggaac atcctattga
     3361 acattgcttg tcaagttaga caagagacgc tcaaatgagt attcataggt ttggatgtct
     3421 cctgctccca taaagacgta aacagcattg tcatggtcta ggagtggaga aacattttca
     3481 acagtaatca cttggtgttt tttgttgatt ttgttggcta ggtcttctac cttaacgtca
     3541 ccatgatcta cttcacgagc cgagccataa atttgcgcta gataaacagc atctgcttgg
     3601 tttaaagcat ggacaaagtc gtccaacaag gcaatggttc ttgtaaaggt atgcggttga
     3661 aagactgcta caatttcctt gcttgggtat ttctgacgag ccgcatccaa ggtcgcaata
     3721 atttctgttg gatggtgggc aaagtcatcg ataatcactg tatcattgac aattttctca
     3781 gtgaaacgac gtttaacacc ggcaaatgtt ttcaagtgct cacgcaccaa gttcaaatca
     3841 aatcctgctg tgtaaagaag accaataacg gctgtcgcat tcatgatatt gtgacgacca
     3901 aaggttggaa tgtggaattg ccccaagttt tgtccacgga aatgaacagt gaaagttgaa
     3961 ccagttgttg aacgaagaag atcactagct acaaagtcat tgccttcaga ttcaaaacca
     4021 taataataaa ttggtgcatc agacgtaatc ttacgcaatt cagcatcttc accatagaca
     4081 aaaagaccct tggtaatttg tttggcatag tcgttaaagg cattgaaaac atccttgaga
     4141 cttgtgaaat aatctggatg gtcaaagtca atgttggtga taatagagta ttctgggtgg
     4201 taaggcatga agtgacgctc atattcatca gattcaaaga caaaatattt ggcattggcc
     4261 gaaccacgac ctgtcccatc tccaatcaag aagctggtat ctgtaatgtg agacaagaca
     4321 tgagacaaca tacctgtcgt tgaagttttt ccatgtgctc ctgctactcc catgctaaca
     4381 aagtcacgca taaagctacc tagaaactca tggtaacgtt tgtagctgat accatttttg
     4441 tccgcatagg caatttcgac gttgttatct ggacgaaagg catttccagc gataatttcc
     4501 atatcaccgt ctagattctt ttcatcaaaa ggaagaatgg taattcctgc ctgctcaaga
     4561 ccgcgttggg taaagtagta cttttcaaca tctgatccct gaaccttgtg ccccatctgg
     4621 tgcaacatca aggccaaggc actcatccct gatcccttaa ttccgataaa atgatatgtc
     4681 tttgacatgt tttctccccc tattctgtca ttctggtcag attcaactct tgggcaaccc
     4741 gacgttcttg ttctgtttgt ttactttttt tattgtagat ttggctcttc tttagaaaat
     4801 cataattgtt tttctttgga gcaggtgctg acacttcttc attcttggta gggatagaat
     4861 gaacttcttc cgccaagata taatgagact gggtcaattt ttggctatat ttgacaaatt
     4921 caccaggatt ttccttttgg aaaggagttg tcggttgatt gccctgtcta actagactgg
     4981 gctgagaatg acgtctcgca aggctgaaat cctgagttag gtagttagca gagcgtttct
     5041 ttttcaagtc cgcacgcgct tcttcacgcg ccacctccgc atagctcttt ccttcttttt
     5101 taacccctaa aggagccttt ttaggtttct cgacttgctt ttcaatcggt tttactggtt
     5161 tttcttcagc aataggagcc cattctaaat aatttttatc tcgatactca cccttgatat
     5221 tactgatcag atcagactca tcatagagat tcatgactgg catttcagtc aacatgacct
     5281 cgtcatctga caccaatgga aatcgttctt gtttcatttt ctatttcctt tcaacacttc
     5341 attatagcgt attgtcttga tttttcaagt gctggcttca gaaattccca aaatttctct
     5401 aatttctgct agggtcagac taccacgtga ctctgtgccg tccaatactt gtgacaccag
     5461 atgtttcttt tgttcttgga gttcctgaat tttttcttca atggttccct tggtcaccaa
     5521 gcgatagacc tcaaccgttt cttcctgacc catccgatgg gcacggccaa tggcttgcgc
     5581 ttccaccgca ggattccacc aaaggtcaac caagatcact gtatctgcac ctgtcaggtt
     5641 cagaccgacc ccaccagcct tgagggaaat cagaaaggca tctctttctc cttgattaaa
     5701 ggccttggtc atgtcttgtc tttccttggc tggggttgaa cccgtaattt taaaggaagt
     5761 caggcccaag tctggcagtt cttgttcaat tttttccaac attcccttga actgagagaa
     5821 aatcaagaca cggtgtccgc cgtctgccac ctgtaccagt aggtctcgga gactatctag
     5881 tttgccactg actccctgat aatcttccat aaacagggta ggagtgtcac atatttgacg
     5941 caagcgcatc aaaccagata aaatttccac acgacttcgc tgaaattcct gttctgacac
     6001 ttgagccaga tggtctcgca tctgttgtaa ctgggcaagg taaatagcct tttgctggtc
     6061 ttccagttca tttttataaa ccacctcaat caagtctggc aattcagtca gaacttcttc
     6121 tttcttgcgt cgcatcacga aaggcttgat aaactgagcc actcgctctg ctggcaattt
     6181 cataaattct ttcttgcttg gcaaaagtcc gggcatgacg atttggaaaa tagaccacag
     6241 ctcacccaga tggttttcaa tcggagttcc tgacaaggca aagaccgacg gcaccacaaa
     6301 ttgtctcaag gtctgggcaa tcttggtctg ggcatttttc atgacctgag cctcatctaa
     6361 gaaaaggaag tcaaaggcca tcccctgata aaactcactg tcctgacgga aggtggcata
     6421 gctagtcaca tagatttgat ggctctcggc aagaatctcc tcacgacttg ctttcaaacc
     6481 atgaacaaca gccacatcca actgtggagc aaatttctga aactcatctg cccagttgta
     6541 aatcaaacct gacggagcga gaatcaaaac ccgactttct tttgtcactt gactagtcaa
     6601 aaaagcaatg gtctgaaggg ttttcccaag tcccatatca tcagccaaaa tcccaccaaa
     6661 accataatga tggagcatct gcaaccagcc aattcccttt tcctgataat ctcgcaagtc
     6721 agcctgaacc tgagttgcct gtcgaggaaa gtcctctgga tgtgtcaaat cctgggccag
     6781 attctggaat tcttgtgaaa aagaaacacg gtctcgccct tcaaagagat gagctaaact
     6841 gtaggccaag gatttcctag cctgcaaagt cccatctttt aattcaaatt gccccagttc
     6901 ctgtaaattt tgacgaattt tcttggtttc ttcatcgaaa aagtaaactt gattagacga
     6961 atcaatataa aaatcctgat tggcaaccaa ggcctgcatg gcttggtcga tttcctcctg
     7021 ggcaatatct tgaaaatcaa actggatttc caagagacct cccttggagg caatctgcac
     7081 ctgaggactc gctaggctat aaagctcttc tagtttatct gataggtcaa catgcccgag
     7141 tttttcaaag actggaatga tatcatgaaa aaaatgatag acagactccg cttttaaggc
     7201 ctgacgccaa gattgaaaat cggcttcaaa gcccgcagcc aaacagactt ggaaaattct
     7261 ttcttctaag tccgcgtcac ttgaaaatgg taattcttct agctcttgtc ggctagatac
     7321 ctgtctattt ccataatcaa actgaatttc taaacgaatc cgattatctt cttccctgtc
     7381 aaagtaaaaa gagggcgcaa aagttttgat ttgtagacgt tctggagctg aaacggtgcc
     7441 catctggata aaaagagtca gacaggaggc caatttgtct cgatcactgc tatcaaattg
     7501 caggtatttc tttccttgtt gacccacagg taacgcttta atttccttga gaagacgcat
     7561 ctgctggtct gttaaaaaat aaacctgacc tttatggaaa agtactgctc cttgataaaa
     7621 gacattgacc ctaggactct cactgatttc catttcaaaa tagtccgagt attctgttac
     7681 tgtaaaggca aatagattgg catcagcatg catatcctga aaaagcaggg tttggtagct
     7741 atccacttga tggtcaaatt gaaaatgggg caaggccatc agtaaattca caccctgctc
     7801 aaaaaaggtc agagggaaaa agaggtgccg accttggttt tggaaaaaga ggtctggaac
     7861 cagcccttcc tccgttagtc cgtgcaagaa agtcaaaagt tcttggctgg catcatcaaa
     7921 ggcttcccaa gaaagagact cctcataaat cttgccaatc atatacgact ttctctgctc
     7981 gacaatcctt aaaaaaagtg gaatatcccg aatgacatag tatttttggc tattgatttg
     8041 gccgattctc agagtccaca agatatgatt ggttcctgct tccacctgac ccacagctga
     8101 taactcatag gcgcatcctg attttggaga taaaattcga tccaaaaact tgccacccaa
     8161 ggtcaccttg gtttcaacgg cctctttttc ttcatgacct tcttccagac tccacaagat
     8221 ttcctgacca cgctcatcat tttttagaaa atgctctagc gctgccaaat gcacacagta
     8281 gcccctcttt tgaaaaaaat cacaggcaca aaaaaccaaa tcatcctcta aactatagcg
     8341 cagttcttct tctgcaacgc gagcgtagag tcgattgttc ttttccttga tgatatcaac
     8401 cttaccagtt tcataaaggg caacaccttc gatacgaatt ttccccggaa tcaatttagc
     8461 catattttca cctttacctt atctgtttat tataccatat tttcgcctat gaaaatagcc
     8521 ttctaggaag acttttctcc tagaaggctg gatttttaac atttggcaaa agtagccaca
     8581 atccgctgac agacttcttg caacagagat ttgggcatag ctatattgat gcgggcatgg
     8641 agacttcctt cctctccaaa atccaaacca cggttgagga taaccttggc ttc
//
LOCUS       DAVDHZ010000066         7932 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000066 DAVDHZ010000000
VERSION     DAVDHZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7932
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.067"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            186..1493
                     /locus_tag="VUR46_002047"
     CDS             186..1493
                     /locus_tag="VUR46_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457400.1"
                     /translation="MLVDFINNSQRQYSFINADGISVEDITDEKNLKFYFYGPVKGEI
                     FRYQEKHDLFLYYRDPLTSVEVPVENTIKVVEMYEETDLIIKVGDYIFQDVKRHRFPD
                     GSVELHFGDCFKMSFDVNKKIFKFNYTRSNMLSKAIECTEVLQELGRVGYFNLNGNKI
                     ELDKQSISDITSQNLDSDIKDLKQISNILKNIGVQKDLDLNCFDKQSQKNLNILNSGL
                     VLKEKVALDYNESKLLHLRIANIHIITLYDYAIDKNGFMINIFTETPWCRRGEDEGGL
                     DISIFEPNYWLKIDNCDFDSVIASYQRLVDNQLRYEGTNNTIIKIVVAADKAEDVSRS
                     ELLLNWAQCLSDWNLKYSKNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYE
                     LCFGSSVLLKSKPQADLFWNKLDNETKERYKDFPIYTLYMKLS"
     gene            complement(1704..2510)
                     /gene="yidA"
                     /locus_tag="VUR46_002048"
     CDS             complement(1704..2510)
                     /gene="yidA"
                     /locus_tag="VUR46_002048"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET5457401.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(2523..3827)
                     /locus_tag="VUR46_002049"
     CDS             complement(2523..3827)
                     /locus_tag="VUR46_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET5457402.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSLIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            3899..4276
                     /locus_tag="VUR46_002050"
     CDS             3899..4276
                     /locus_tag="VUR46_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET5457403.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGNYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            4367..4699
                     /locus_tag="VUR46_002051"
     CDS             4367..4699
                     /locus_tag="VUR46_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET5457404.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            4711..6282
                     /gene="ffh"
                     /locus_tag="VUR46_002052"
     CDS             4711..6282
                     /gene="ffh"
                     /locus_tag="VUR46_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET5457405.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHQVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPI
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSAPGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(6477..7760)
                     /locus_tag="VUR46_002053"
     CDS             complement(6477..7760)
                     /locus_tag="VUR46_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET5457406.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
BASE COUNT         2512 a         1376 c         1747 g         2297 t
ORIGIN      
        1 ggtggtgtgg ttttattcgt tgtctggcta agtgaaaata atgatttaag agaaatatac
       61 tataagtcat tgcctccttt atctataaaa aaattgctaa aaaaagtaga ttaaataata
      121 aaactacaaa tagtaagaaa ctttctgttc ggatatttaa attggatgag aaagaaatgt
      181 atccaatgtt agtggatttt attaacaata gtcagaggca gtatagtttc ataaatgcag
      241 atggaatttc cgttgaggac attactgatg aaaaaaatct aaagttttac ttttatggtc
      301 cagtgaaagg agagatcttt cgttatcagg aaaagcatga tctttttcta tattacagag
      361 atcctcttac tagtgttgaa gtaccagttg aaaataccat aaaagttgtc gaaatgtacg
      421 aagagactga tcttatcatt aaagttggtg attatatttt tcaagatgta aaaaggcatc
      481 gttttcctga tgggagtgta gaactccatt ttggtgattg ttttaaaatg tcctttgatg
      541 taaataaaaa aatatttaaa tttaactata caaggtccaa tatgctatca aaagctatag
      601 agtgtacgga ggtgctccaa gagctaggaa gagtaggata tttcaatctc aacggaaata
      661 aaatagaact agataagcag tcaatatcgg atatcacttc acagaattta gatagtgata
      721 taaaggattt gaaacagatt tctaacatat taaaaaatat aggtgtacaa aaggatctag
      781 atctaaactg ctttgataaa caatctcaaa aaaatctaaa tatcctaaat tcagggcttg
      841 ttctaaagga gaaggttgcc ttagattata atgagtccaa attacttcat ttaagaattg
      901 ctaatatcca tattattacc ttatatgatt atgcaataga taagaacggt tttatgatta
      961 atatctttac tgaaactcct tggtgtagga gaggtgaaga tgaaggtggt ttagatattt
     1021 caatttttga acctaactat tggctaaaaa tagataattg tgattttgat tcggttattg
     1081 cctcttacca aagattagtt gataatcaat tgagatatga aggtactaat aacactatta
     1141 taaaaatagt tgtggctgct gataaggcag aagatgtttc tagaagtgag ttattgctta
     1201 attgggcaca atgtctttct gactggaact taaaatactc aaaaaattgt gagatggcta
     1261 taataaatga ccttcaaata aaatctagag ttcgtaaatt aaacagcaaa gaaacagaga
     1321 cactaactaa tattttagta aatagtaatg ataactatga actttgtttc ggttcatcag
     1381 tgctattaaa atcgaaacca caagctgatt tgttttggaa taaactggat aatgagacaa
     1441 aagaaagata taaggacttt cctatttata ctttgtatat gaaattatcg taaaattaaa
     1501 agagattata aagagataac atatagaaat agagagtgat ttattacaat tcagtaccac
     1561 aaattaagaa agcaatgcct attttttgta ctctcaagat ttaagtaact gtacaactgc
     1621 aattaaattt attaatttac tctcattgtg atatattcat acaaaaaccg ctcagctgag
     1681 cggtttttat ctattctttc cttttacagt acccatgttc ggatggcatg ggcaacgccg
     1741 gattcgtcat ttgttttggt gatgtatttg gcgatttttt tgatttctgg atttccattt
     1801 tccatgacaa cggggtttcc aacgacttcc agcatggcac ggtcattttc ttcatcaccg
     1861 attgccatgg tttcatcttt ggtcaatccg agtttttcag ccaagtgagt aatggctgaa
     1921 cccttgtcta cattcttttt aaggagttcg aggtagaaag gagcagattt gttgatggag
     1981 tagcgctcgt aaaattctgc tggaattttt tcaatcgcag catcgagaat ttctggttca
     2041 tcgataaaca tacatttaac aatttctttg ccagccattt cttcaggggt acggtagaag
     2101 ataggcatgc tgacgagggt tgattcgtgt acagtgtatt ttccgatatt gcgatttgca
     2161 gtatagatac cgtccttggt aatggcatgc atgtggacac cgagcttgcg actgaggaat
     2221 tccatatcca gataatcctc ataggtcaag gattcgctga taatctcatg gccagtagca
     2281 gtttcttgga caagggcacc attgaaggtc accacatagt caccttggtc tctcaactgc
     2341 aagtcgtcca gaagtttggc aacacctgcg atggggcggc cagttgcaat cacgactttg
     2401 acaccagctt ctttggcatc ttggatggca gaaaagactt caggagtgat ttccttttgg
     2461 ctgttgacta gggttccgtc aatatcgacg gcaattagtt taatactcat aaatttcctc
     2521 ttctagtttt tatttggggt aaaatgatcg ttctcaatca agtgtaaaaa ttgctgggta
     2581 atgcttgcga agatgctgtt ttggtctaac atttctttag ggaaatagaa acgattatct
     2641 ccgtggcgac tgccagcaag ggattggacg ataagagaca ggctagagag ttcggccagt
     2701 tctccatttt tttgtaaaat ctcaatctgt gtccgtgggt tttcagattc gggacgatag
     2761 atatcataag ggaggtcaaa gttcttatga atggcagtat agtagtcggg atcaaagccg
     2821 atgtcctcaa ccaattttct catgctagta agttgatctt ggtcctcttg tgaaaaggta
     2881 atggatttaa agaccttgcg gttgacaaag cgttgagata aatctgcaag aattttgtca
     2941 ggactagtca tccaaagctg gaagtaggta ttcatcacgc catcatccag agccagatag
     3001 tcagtcaagg tcacattttt ttcgaagaaa ggcaggagat gtggggaagt tcgtgcaaag
     3061 aaattcttgt cctcagggta gagttccttg gcgcgcttga gaagattctg taggagaact
     3121 tccatggcgc gtgttgctgg gtggaaataa acctgcatgt acatctggta gcgactgagg
     3181 acgtagtctt cgatggcgtg catgccattg cgctgaaagg cgataccatt ttcgacagga
     3241 cgaatgactc ggaggatgcg agtcaggtca aattccccat aggatgctcc tgtaaaatag
     3301 gagtcgcgca agagatagtc catgcgatct gcgtcaatct gactagaaat gagctgcacg
     3361 acctgcttat taggataggt atggtcaatg acactggcca ccttttctgg gaaatcaggt
     3421 gccacttgta gcaggacttg gtgaatctct gtctcaggat tttgaataat ctcctgagta
     3481 atggcttcat ggtctgtatc aaagagattt tcaaaagtat gggagtaggc accatgccca
     3541 aggtcgtgta ggagagcagc ggtcatggtc aagagagact cggcaggatt ccattcctca
     3601 ggatattttt cttcgaaaat ctctgtgatg cgtcgtgcaa tttcatagac tcctagacag
     3661 tgagagaagc gactgtgttc tccaccgtgg aaggtataac tggaagttcc cagttgtttg
     3721 atccggcgca aacgctgaaa ttcttttgta ttaatcaagt catagatgat ttgattattg
     3781 acatggatgt agttgtgaac tgggtcacgg aatacttttt cgttcatatg accattatag
     3841 caaaatcctg ctctttttgg taaaatagta ggacaagaga caagaaagag gacttgatgt
     3901 gaagattcgg atgcgaaata cgattcagtt tgatgagcag ttggaagtga ttgaccagct
     3961 ttatgatgtg gaagtgcatg aaaagggaaa ttatagctat ttactctttt ataatgagga
     4021 aaaggaaaaa gtagtgatta aatttcatgg tcaagaactt gtgatgagcc gattttctaa
     4081 tcccaagacc attatgcgct ttctaaagga tagcgatagt ttagcctata ttcctacacc
     4141 tatgggcatg caggagttta tcatccaaac gagccattat caagttgata ggcaaaagat
     4201 tgaactagat tatcaactac aaaatcaaga gggacatccc tttgccagct atcaattgga
     4261 aattacttgg ggctaggctc atgtcttttt caaatttagc tatctatctt cttggatcgg
     4321 cttcctagtg tggtagatta ggctaatttt tggtataata aaagttatgg aaatcgaaaa
     4381 aaccaatcgt atgaatgcgc tctttgaatt ttatgcggcg cttttgacag ataagcaaat
     4441 gaattatatc gagctctact acgctgatga ttacagcctt gctgaaattg ccgaggagtt
     4501 cggtgtcagt cgtcaggctg tctatgacaa tatcaagcga acagaaaaga ttctggaaga
     4561 ttatgagatg aaattgcaca tgtactcgga ctatattgtc cgcagtcaga tttttgatca
     4621 gattttggag cgctatccca aggataactt tctgcaggag cagatagaaa ttttaacaag
     4681 cattgataat agagaataag aggaagaaaa atggcatttg aaagtttaac agaacgtttg
     4741 cagaacgtct ttaaaaatct acgtaaaaaa ggaaaaatct ctgaatctga tgtccaagag
     4801 gcaaccaaag aaattcgctt ggccttgctc gaggccgacg ttgccttgcc tgttgtaaag
     4861 gactttatca agaaagttcg tgagcgtgca gtcgggcatc aggtcattga tacacttaat
     4921 cctgcgcaac agattattaa aatcgttgat gaggaactga cagccgtttt aggttctgat
     4981 acggcagaaa ttatcaagtc acctaagatt ccaatcatca tcatgatggt tggtttacaa
     5041 ggggctggta aaacaacctt tgctggtaaa ttggccaaca aactcaagaa agaagaaaat
     5101 gctcgtcctt tgatgattgc ggcggatatt tatcgtccag ctgccattga ccagcttaag
     5161 accttgggac aacagattga tgtgcctgtc tttgcacttg gaacagaagt accagctgtt
     5221 gagattgtac gtcaaggttt ggagcaagcc caaactaatc ataacgacta tgtcttgatt
     5281 gatactgcgg gtcgtttgca gattgatgag ctcctcatga atgagcttcg tgatgtgaaa
     5341 gcattggctc aaccaaatga aatcttgctt gtcgttgatg ctatgattgg tcaggaagca
     5401 gccaatgttg cgcgtgagtt taatgctcag ttggaagtga ctggggtcat ccttaccaag
     5461 attgatggcg atactcgtgg tggtgctgct ctgtctgttc gtcacatcac tggaaaacca
     5521 atcaagttca ctggtacagg tgaaaaaatt acagatatcg aaaccttcca cccagaccgt
     5581 atgtctagcc gtatccttgg catgggggat atgctcactt tgattgagaa agcttctcag
     5641 gaatacgatg aacaaaaagc ccttgaaatg gctgagaaga tgcgcgaaaa tacctttgat
     5701 ttcaatgatt tcattgatca gttggatcag gtacaaaaca tggggccaat ggaagacttg
     5761 ctcaagatga ttccaggtat ggccaataat ccagcacttc aaaacatgaa ggtggatgaa
     5821 cgccagattg ctcgtaaacg tgccattgtg tcttcgatga cacctgaaga acgtgaaaac
     5881 ccagatttgt taaatccaag ccgtcgccgt cgtattgctg ctggttctgg aaatacattc
     5941 gtcgaagtca ataaattcat caaggacttt aaccaggcta aacagctcat gcagggtgtt
     6001 atgtctgggg atatgaataa aatgatgaag caaatgggga ttaatccaaa taaccttcct
     6061 aaaaatatgc caaatatggg aggaatggat atgtctgccc ttgaaggaat gatgggacaa
     6121 ggcggtatgc ctgacttatc agctcccgga ggagcaggaa tgccagatat gagccagatg
     6181 tttggtggcg gtttgaaagg taaaattggt gaatttgcca tgaaacagtc catgaaacgt
     6241 atggctaaca aaatgaagaa agcgaagaag aaacgcaagt aagacaagag attgatgcaa
     6301 atctcatttg atgagaaaat aaagtaaaaa tttctatgat aaaacgtaca gtatcaaggt
     6361 tttagaatat ctgatattat acgttttttg attttaataa ttttgttaag acacttttat
     6421 tatggtatac gaaaaatcca ctcagacagc tgagtggatt aggtgtattt agactcttag
     6481 tctttatttt cgtatggcaa gatcaagttc aagatgattc ctgtcatggc tgaaagggca
     6541 gtacctgaaa gtgtaactgg accaagttta aggatagctc ctccaagtcc aagaaccaac
     6601 atagcacttg cgatgatgag gtttcgcatt tgagcgaaat caacacgttc tttaatcaag
     6661 actttcaaac cattgctggc gataacccca tagagaagga ttgacatacc accaagtaca
     6721 gcgtttggaa tagttgaaat caaggcagtg aatttaccaa ggaagctgag ggcaatcgcg
     6781 atgaaggcag cgttacggat aactgagaca gaagcgatac gagtcatacc gataacccct
     6841 gtattttctc cgtaagttgt attggctggt ccaccaagga aggcagaaac agaagttgcg
     6901 ataccgtcac caataagagt acggtgaaga cctggttctt ttaagaattg acggccacag
     6961 atttgaccca aaacagtatg gtctccgata tgttcagaaa ttgttacgat agcgattggc
     7021 aagatagcga tggcttctgg accaaagtaa agattgtact ctttaaaggc accacctgtg
     7081 ctaaatggca agtagaaacc aggaatttca aaccagttag cttctaggac aggcgtaaag
     7141 tcaaccaaac caagagttag tgcgaagagg taaccaccga taatggcaaa gaggaatgga
     7201 atgattcgta ggaagccttt tccttttgta ttgataaagg cagcaattag gaaagtaaca
     7261 acggctacca gagcattttt ccaatttccg tctgctacaa gacctgcatt ggtaacagct
     7321 gaacctgcaa gtccaagacc gataacgatg atcataggac cgataatgat tggtggcaag
     7381 agtttatcaa tccattttgt tcctacaaat cggatgctgg tagcaacaag gacatagacc
     7441 aaaccagtca agataacccc tgtttgagca gcagatacat ccccccccat ttctttcata
     7501 gccagtgaca tagctgtgat aaaggcgaat gaagaaccta gataaactgg aactttaaaa
     7561 ccagtagcaa tcatgtaaat gagtgttcca acacctgaag caaaaagggc aacagataca
     7621 ggcattccca aaatcaatgg taccaagatg gtcgcaccaa acatggcgaa aacgtgttgg
     7681 aaactaagga gaattccttt tccagccgaa ggacgttggt caacgtctag taacaaatca
     7741 acagttgatt cttgtttcat ataaacctca cttttgggca tcaaaaaaga gcccattatt
     7801 ttacagcaat aggccctcag agtaagactt ctttaaaatt tagattttaa agagttttaa
     7861 atatttctgc gtcttcgtca cctcacggga tgacattaaa aacctttgct taggatagta
     7921 tagcagaaaa aa
//
LOCUS       DAVDHZ010000067         7904 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000067 DAVDHZ010000000
VERSION     DAVDHZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.068"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            138..1838
                     /gene="dnaG"
                     /locus_tag="VUR46_002054"
                     /pseudo
     CDS             138..1838
                     /gene="dnaG"
                     /locus_tag="VUR46_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014178.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            1916..3025
                     /gene="rpoD"
                     /locus_tag="VUR46_002055"
     CDS             1916..3025
                     /gene="rpoD"
                     /locus_tag="VUR46_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET5457407.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVVPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            3039..3368
                     /locus_tag="VUR46_002056"
     CDS             3039..3368
                     /locus_tag="VUR46_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET5457408.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            3483..4526
                     /gene="cpoA"
                     /locus_tag="VUR46_002057"
     CDS             3483..4526
                     /gene="cpoA"
                     /locus_tag="VUR46_002057"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET5457409.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGISREKVSYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPVALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            4542..5867
                     /locus_tag="VUR46_002058"
     CDS             4542..5867
                     /locus_tag="VUR46_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET5457410.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            5896..6072
                     /locus_tag="VUR46_002059"
     CDS             5896..6072
                     /locus_tag="VUR46_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET5457411.1"
                     /translation="MRSGRDKKIAGVCAGVAHYFDMDPTIVRVIWGVLAFGYGAGVIA
                     YIILWIIAPVVTDY"
     gene            6131..6265
                     /locus_tag="VUR46_002060"
     CDS             6131..6265
                     /locus_tag="VUR46_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET5457412.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            6329..7639
                     /gene="obgE"
                     /locus_tag="VUR46_002061"
     CDS             6329..7639
                     /gene="obgE"
                     /locus_tag="VUR46_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET5457413.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            7649..7807
                     /locus_tag="VUR46_002062"
     CDS             7649..7807
                     /locus_tag="VUR46_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457414.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         2374 a         1407 c         1856 g         2267 t
ORIGIN      
        1 aagtcccgaa aatcccctta tatcaacctt tatgaggagt ttttcacttc acaactgtca
       61 aagtcccggg aaaatgagtg aaatggttta ctttttttct gaaataaagt atactatata
      121 aagtaaacta tgataacatg gaggtattgt gtatggttga caaacaagtc attgaagaaa
      181 tcaaaaacaa tgccaacatt gtggaagtca taggagatgt gatttcttta caaaaggcag
      241 gacggaacta tctagggctc tgtccttttc atggtgaaaa aacaccttct ttcaacgttg
      301 tagaggacaa gcagttttac cactgttttg gttgtggtcg ctctggtgat gtctttaagt
      361 tcatcgagga gtaccaaggg gttcccttta tggaagccgt ccaaatctta ggtcagcgtg
      421 ttggaattga ggttgaaaaa ccgctttata gtgaacagaa gtcagcttcg cctcaccaag
      481 ctctttatga tatgcacgaa gatgcagcca aattttatta cgctattctc atgacaacga
      541 ctatgggaga agaggcgaga aattaccttt atcagcgtgg tttgacagat gaagtgctga
      601 aacattttcg gattggtttg gcaccaccag aacgaaacta tctctatcaa cgtttgtctg
      661 gtcagtaccg tgaagaagat ttcttggatt caggcctgtt ttacctctcg gatgccaatc
      721 aatttgtaga cacctttcat aatcgcatta tgtttcccct gacaaatgat cagggaaagg
      781 tcattgcctt ctcaggtcgt atctggcaga aaacggattc acaaacttct aagtataaaa
      841 atagccgatc gactgcaatt tttaacaaaa gttacgaatt atatcatatg gatagggcaa
      901 aaaaatcttc tggtaaaacc agtgagattt acctcatgga aggattcatg gatgtcattg
      961 cagcctatcg ggctggaatc gaaaatgctg tggcatctat gggaacggcc ttgagtcgtg
     1021 agcatgttga gcatctgaaa aggttaacca agaagttggt tcttgtttac gatggcgata
     1081 aggctgggca agccgcgact ttgaaagcgc tggacgaaat tggtgatata cctgtgcaaa
     1141 ttgtcagcat gcctgataac ttggatccag atgagtatct acaaaaaaat ggaccagaag
     1201 acttggccta tctattaacg aaaactcgta ttagtccgat tgagttttac attcaccagt
     1261 acaaacctga aaatagtgaa aatctgcagg cccagattga gtttattgaa aaaatagctc
     1321 ccttgattgt tcgagaaaaa tctattactg ctcaaaacag ctatattcat attttagctg
     1381 acagtctggc gtcctttgat tatgctcaga ttgagcagat tgttaatgag agtcgtcagg
     1441 cgcaaaggca gaatcgcatg gaaggggttt ccagaccgac gccaatcact atgcctgtca
     1501 ccaagcagtt atcggctatt atgagggcag aagctcatct actttatcga atgatggaat
     1561 ctcctcttgt tttgaacgat taccgtttgc gggaagactt tgcatttgcc acacctgaat
     1621 ttcaggtctt atatgacttg cttggtcagt atggcaatct tcctccagaa gttctagcag
     1681 aacagacaga ggaagttgaa agatcttggt accaagtttt agctcaggat ttacctgctg
     1741 agatgtcacc gcgggaacta agtgaagtag aaatgactcg aaacaaggct ctcttgaatc
     1801 aggacaatat gagaatcaaa aagaaggtgc aggaagctag ccatgtagga gataccgaca
     1861 cagccctaga agaattggaa cgtttaattt cccaaaagag aagaatggag taataatggc
     1921 aacaaaacaa aaagaagtaa caacatttga cgtacaagta gcagaattta tccgtaatca
     1981 taagcaaaaa gggacagcaa cagatgatga aatcaatgct agtcttgtcg ttccttttac
     2041 cttggacgct gatgggattg aagatctctt gcaacggatt caggatgcgg gaatttctat
     2101 cacagataac gaaggaaatc caagtgcgcg tgttcttagc aatgaagaag aaccagaact
     2161 cagcgatgag gacttgattg ggtcaacttc tgctaaggtc aatgaccctg tccgtatgta
     2221 cttgaaagaa ataggggtcg ttcctctctt gaccaatgaa gaggagaaag agttggcact
     2281 ggctgttgaa gctggtgata tcgaagccaa acaacgtctt gcggaagcca atcttcgttt
     2341 ggttgtttcc attgccaaac gctatgtcgg tcgtggcatg cagttccttg acttgattca
     2401 agaaggaaat atgggcttga tgaaggcggt tgacaagttt gactattcta aagggttcaa
     2461 gttttcaact tatgcaactt ggtggattcg tcaggctatc actcgtgcta ttgcggatca
     2521 agctcgtacc atccgtatcc cagttcacat ggttgaaact atcaataaat tggttcgtga
     2581 acagcggaat ctccttcaag aattggggca agatccgaca ccagaacaga ttgctgaacg
     2641 aatggatatg acacctgata aggttcgtga aatcttgaag attgcccaag aaccagtatc
     2701 tcttgaaact cctatcggtg aagaggacga tagccacctt ggagacttta tcgaagatga
     2761 agtgattgaa aatccagtgg attatacgac tcgtatcgtc ttgcgtgagc aattggatga
     2821 aatcttagat actcttacag accgtgaaga aaatgttctg cgtctacgtt ttggactaga
     2881 tgatggaaaa atgcgcacac ttgaagatgt ggggaaagtc tttaacgtaa ctcgtgagcg
     2941 tatccgtcag attgaagcaa aggctttgag aaaactacgc caaccaagtc gcagcaaacc
     3001 gcttcgtgat tttattgaag actaagagtg aggaaaatat ggcttataca gaagagcaaa
     3061 ttgaaaacat caaaacacgg attttaacag ccttggaaga agtcatcgac cctgagttgg
     3121 gaatcgatat tgtcaatctt ggtttgatct atgagattcg ttttgacggt gacacagggc
     3181 aaacagagat tgacatgact ttgacaacta tgggttgtcc cttagcagac cttttgacag
     3241 accagattta tgatgctatg atagaggttc cagaagtaac ggatactgag gttaaattag
     3301 tctggtatcc agcctggaca gttgaaaaaa tgagtcgcta tgcccgcatt gccctaggca
     3361 ttaagtaaac atataaaagc atgtgagaga ctgttggaaa agcgaggaaa tttcccctct
     3421 tttcctctag tctctccttt cttttgctga ttttattcaa agaaaatgat ataatagtag
     3481 ttatggagaa aaagaaatta cgcatcaata tgttgagttc aagtgagaaa gtagcaggac
     3541 aaggagtttc aggtgcttac cgtgaattag ttcgtcttct tcaccgtgct gccaaggacc
     3601 aattgattgt tacagaaaat cttccaatcg aggcagatgt gactcacttt cataccattg
     3661 attttcccta ttatttatca accttccaaa agaaacgctc agggagaaag attggctatg
     3721 tgcatttctt gccagctaca cttgagggaa gtttgaaaat tccatttttc ttaaagggaa
     3781 ttgtgaaacg ctatgtattt tctttttaca accggatgga gcacttggtt gtggtcaatc
     3841 ctatgtttat tgaggatttg gtagcagctg gtatttcacg tgaaaaagtg agctatattc
     3901 ctaactttgt caacaaggaa aaatggcatc ctctaccaca agaagaggta gtcagactgc
     3961 gcacagatct tggtcttagt gacaatcagt ttatcgtagt aggtgctggg caagttcaga
     4021 aacgtaaagg gattgatgac tttatccgtc tggctgagga attgcctcag attaccttta
     4081 tctgggctgg tggcttctct tttggtggta tgacagatgg ttatgaacac tataagaaaa
     4141 ttatggaaaa tccccctaaa aatttgattt ttccaggcat tgtatcgcca gagcggatgc
     4201 gcgaattgta tgctctagcg gatcttttct tgttgcctag ttacaatgag ctctttccta
     4261 tgactatttt agaagctgcg agttgtgagg ctcctattat gttgcgtgat ttagatctct
     4321 ataaggtgat tttggaggga aattatcggg cgacagcggg tagagaagag atgaaagagg
     4381 ctattttgga atatcaagca aatcctgttg ccttaaaaga tctcaaagaa aaggctaaga
     4441 atatttccag agagtattct gaagagcatc tgttacaaat ctggttggac ttttatgaga
     4501 aacaagccgc tttagggaga aagtaaaaag tgaggtaatc tatgcgaatt ggtttattta
     4561 cagataccta ttttcctcag gtttctggtg ttgcgaccag tattcgaacc ttgaaaacag
     4621 aacttgaaaa gcagggacat gctgttttta tctttacgac gacagataag gatgtcaatc
     4681 gctacgaaga ttggcaaatt atccgcattc caagtgttcc tttctttgct tttaaggatc
     4741 gtcgctttgc ctaccgaggt tttagcaagg cacttgaaat tgctaaacag tatcagctag
     4801 atattatcca tactcagaca gaattttctc ttggcctgtt ggggatttgg attgcgcgtg
     4861 aattgaaaat tccagtcatc catacctatc acacccagta tgaagactat gtccattata
     4921 ttgctaaggg gatgttgatc cggccgagta tggtcaagta tctggttaga ggtttcctgc
     4981 atgatgtgga tggggttatt tgccctagtg agattgtccg tgacttgcta tctgattata
     5041 aggtcaaggt tgaaaaacgg gtcattccta ctgggattga attagccaag tttgagcgtc
     5101 cggaaatcaa gcaggaaaat ttgaaagaac tgcgtagtaa actagggatt caagatggtg
     5161 aaaagacgtt gcttagtctt tcgagaatct cctatgaaaa aaatattcaa gcagttttag
     5221 cagcctttgc tgatgttctg aaagaggaag acaaggttaa actggtagta gctggggatg
     5281 gcccttatct gaatgacctc aaagagcaag cccagaacct agagattcaa gactcagtca
     5341 tctttacagg gatgattgct cctagtgaga cggctcttta ctataaagcg gcggatttct
     5401 tcatttcggc atcgacaagc gaaacgcaag gtttgaccta cttggaaagc ttagccagtg
     5461 gaacacctgt cattgctcac ggaaatcctt atttgaacaa cctcatcagt gataaaatgt
     5521 ttggaacctt gtactatgga gaacatgatt tggctggtgc tattttggaa gccctgattg
     5581 caacaccaga catgaacgag cataccttat cagagaaatt gtatgagatt tcagctgaga
     5641 actttgggaa acgagtgcat gagttttatc tggatgctat tatttcaaat aacttccaga
     5701 aagatttggc taaagatgat acggtcagtc agcgtatctt taagacagtt ttgtatcttc
     5761 cgcaacaggt ggttgctgta cctgtaaaag gttctagacg catgttgaag gcttcaaaaa
     5821 cacagttgat cagtatgaga gattattgga aagaccatga agaatagaaa gaggaacagt
     5881 atgaaaaaac aattaatgag aagcggtcgt gataaaaaga ttgctggtgt ttgtgctggg
     5941 gtagcccatt attttgatat ggatcctact attgttcgcg taatatgggg tgttcttgct
     6001 tttggttatg gagcaggagt tatagcttat atcattttat ggattatcgc acctgtagta
     6061 actgactatt gaaaactagc taaattcatg ctaagataat agaaaataga atgcaacgaa
     6121 ggagagaaaa atggcatttg gagataatgg aaatcgtaaa aaaactatgt ttgagaaaat
     6181 aaccttgttt atcgtgatta tcatgctagt agcaagttta ttgggaattt ttgcaactgc
     6241 aattggtgcc ctcagtaatc tataaaatag attcaagaaa atttagtgac tgggatttcc
     6301 cagccctttt ttaaagtgag aagaaaaaat gagtatgttt ttagatacag ctaagatcaa
     6361 ggtcaaggct ggtaatggtg gtgatggcat ggttgccttt cgccgtgaaa aatatgtccc
     6421 taatggtggt ccttggggtg gtgatggtgg tcgtggaggc aatgtggtct tcgttgtaga
     6481 cgaaggacta cgtaccttga tggatttccg ctacaatcgt catttcaagg ctgattctgg
     6541 tgaaaaaggg atgaccaaag ggatgcatgg tcgtggtgct gaggacctta gagttcgagt
     6601 accacaaggt acgactgttc gtgatgcgga gactggcaag gttttaacag atttgattga
     6661 acatgggcaa gaatttatcg ttgcccacgg tggtcgtggt ggacgtggaa atattcgttt
     6721 cgcgacacca aaaaatcctg caccggaaat ctctgaaaat ggagaaccag gtcaggaacg
     6781 tgagttacaa ttggaactaa aaatcttggc agatgtcggt ttagtaggtt tcccatctgt
     6841 agggaaatca acacttttaa gtgttattac ctcagctaaa cctaaaattg gtgcctacca
     6901 ctttaccact attgtaccaa atttaggtat ggttcgcacc caatcaggtg aatcctttgc
     6961 agtagccgac ttgccaggtt tgattgaagg ggctagtcaa ggtgttggtt tgggaactca
     7021 gttcctccgt catatcgagc gtacacgtgt tatccttcac atcattgata tgtcagctag
     7081 cgaaggccgt gatccatatg aggattacct agctatcaat aaagagctgg agtcttacaa
     7141 tcttcgcctc atggagcgtc cacagattat tgtagctaat aagatggaca tgcctgagag
     7201 tcaggaaaat cttgaagact ttaagaaaaa attggctgaa aattatgatg aatttgaaga
     7261 gttaccagct atcttcccaa tttctggatt gaccaagcaa ggtctggcaa cacttttaga
     7321 tgctacagct gaattgttag acaagacacc agaatttttg ctctacgacg agtccgatat
     7381 ggaagaagaa gcttactatg gatttgacga agaagaaaaa gcctttgaaa ttagtcgtga
     7441 tgacgatgcg acatgggtac tttctggtga aaaactcatg aaactcttta atatgaccaa
     7501 ctttgatcgt gatgaatctg tcatgaaatt tgcccgtcag cttcgtggta tggggggtga
     7561 tgaagccctt cgtgcgcgtg gagctaaaga tggggatttg gtccgcattg gtaaatttga
     7621 gtttgaattt gtagactagg agactggtat gggagataaa ccgatatctt tccgagatgc
     7681 ggatggtaat tttgtttccg ccgcagacgt ttggaatgaa aagaaattgg aagaactatt
     7741 taatcgtctc aatccaaatc gtgccttgag attggcacga actaaaaagg aaaatccatc
     7801 tcagtaaaga agctaaaaaa tcccggctct ttgtcaactg tagtgggttg aagtcagcta
     7861 agctcgagaa aggacaaatt tcgtcctttc ttttttgatg ttca
//
LOCUS       DAVDHZ010000068         7364 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000068 DAVDHZ010000000
VERSION     DAVDHZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.069"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..930
                     /gene="lytB"
                     /locus_tag="VUR46_002063"
     CDS             <1..930
                     /gene="lytB"
                     /locus_tag="VUR46_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET5457415.1"
                     /translation="WYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVP
                     VTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASK
                     DFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFK
                     DLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNW
                     GRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNK
                     ASGMNVEYASDPYWGEKIASVMMKINEKLGGKN"
     gene            complement(991..2646)
                     /gene="pavA"
                     /locus_tag="VUR46_002064"
     CDS             complement(991..2646)
                     /gene="pavA"
                     /locus_tag="VUR46_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET5457416.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMILRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMRKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHRVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2751..3248
                     /gene="ybeY"
                     /locus_tag="VUR46_002065"
     CDS             2751..3248
                     /gene="ybeY"
                     /locus_tag="VUR46_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET5457417.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMFEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3229..3624
                     /locus_tag="VUR46_002066"
     CDS             3229..3624
                     /locus_tag="VUR46_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET5457418.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3641..4540
                     /gene="era"
                     /locus_tag="VUR46_002067"
     CDS             3641..4540
                     /gene="era"
                     /locus_tag="VUR46_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET5457419.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKATKVPVILVVNKIDKVHPDQLLSQIDDFRNQIDFKEIVPISALQGNNMSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDCMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            4589..5413
                     /gene="mutM"
                     /locus_tag="VUR46_002068"
     CDS             4589..5413
                     /gene="mutM"
                     /locus_tag="VUR46_002068"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET5457420.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LTSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKAGQACSRCGTVIEKFQLGGRGTHFCPNCQRRD"
     gene            5413..6018
                     /locus_tag="VUR46_002069"
     CDS             5413..6018
                     /locus_tag="VUR46_002069"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET5457421.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRKQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6005..7204
                     /locus_tag="VUR46_002070"
     CDS             6005..7204
                     /locus_tag="VUR46_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET5457422.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVSFMSIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNETALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7204..7353
                     /gene="rpmG"
                     /locus_tag="VUR46_002071"
     CDS             7204..7353
                     /gene="rpmG"
                     /locus_tag="VUR46_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5457423.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
BASE COUNT         2029 a         1401 c         1696 g         2238 t
ORIGIN      
        1 tggtactact tcaaatctgg tggctacatg gcgaaaaatg agacagtaga tggttatcag
       61 cttggaagcg atggtaaatg gcttggagga aaagctacaa atgaaaatgc tgcttactat
      121 caagtagtgc ctgttacagc caatgtttat gattcagatg gtgaaaagct ttcctatata
      181 tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa gcgcttggct
      241 attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc gctagatgct
      301 agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca ctatgtggct
      361 cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg caagaaatat
      421 tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt ccttttcaaa
      481 gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt tagtttgcta
      541 aacattaata atagcctttt ggagaacaag ggcgctactt ttaaggaagc cgaagaacat
      601 taccatatca atgctcttta tctccttgcc catagtgccc tagaaagtaa ctggggaaga
      661 agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga tacgacccct
      721 tacctttctg ctaagacatt tgatgatgtg gataagggaa ttttaggtgc aaccaagtgg
      781 attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc ttctggtatg
      841 aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt gatgatgaaa
      901 atcaatgaga agctaggtgg caaaaattag tactataagt gaatatgatt tgagtgaata
      961 gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg caattttttt
     1021 ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc cgggttttcc
     1081 accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca gattcgacag
     1141 gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtctttactg catcagatgg
     1201 gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat ggaaccaaag
     1261 ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt ttcgtccgac
     1321 atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc gtttctggat
     1381 tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac ggatttcagc
     1441 gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat agagaatagt
     1501 ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga gtttctgata
     1561 ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa gcgcaatcat
     1621 gataggttgg ttggtatagt agttgtctag gataacctga tcttggtcgt taggcactcg
     1681 gtggaggaag gttgtcagta attctccttt ttgacgaaat tcttcagcgt tgtctgtcgc
     1741 cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt cattttcaac
     1801 acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct tatccttata
     1861 gtaggtgtcc aacaaatcag aaagatttgc aaaaggctct cccacctgat ttgcaaaagg
     1921 aactggactg aaggaagtct cagtcaagca tggcttggtt tcttgattga aaaaatttcg
     1981 gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg tatcgcgtcc
     2041 cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt gcaggatttc
     2101 aaagagcttt tcatccttga tagtaaaagg attgagagat tctgtacttg gcggagcgat
     2161 ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaagccga cgtgtttgat
     2221 aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt gtttcctcat
     2281 aatttcgata atcaaggtag cctggatatg gtctccaatc tcgtttttat tggaaactgt
     2341 aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg ccccctgcaa
     2401 atactttctc aaaatcatga taaaggtaga aggttgggct ggattttcaa aagtcgtttg
     2461 ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat ggctttggcg
     2521 attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt tctggatgcg
     2581 accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa atccgtcaaa
     2641 tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag gtagaataaa
     2701 atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac atgtatattg
     2761 aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc caagaaattt
     2821 tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc acttttgtga
     2881 ccaatgagcg tagtcatgaa cttaatctgg agtaccgtga caccgaccgt ccgacagatg
     2941 tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag gatttgcttg
     3001 aaaatccaga attggcagag atgatgtttg agtttgatgc ctatattggg gaattgttca
     3061 tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt gagcgtgaga
     3121 tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac tacactccgg
     3181 aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat ggactcacaa
     3241 gacaataaac gaaaatggaa aaatcgtgac ttgatatcca gtttagaatt tgctttgaca
     3301 ggtattttta ctgctatcaa ggaagaacgc aatatgcgaa aacacgcagt gacggctcta
     3361 gtggtcatcc ttgcaggttt tgtttttcag gtgtcacgaa tcgaatggct ctttctccta
     3421 ttgagcattt tcttggtagt agcctttgag attatcaact ctgctattga aaatgtggtg
     3481 gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga tatggcggct
     3541 ggcgcggtat tagtggtttc tcttttcgca gccttaacag gcgcattgat ttttctccca
     3601 cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta aatcaggctt
     3661 tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc acgttatggg
     3721 gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa tcatgggaat
     3781 ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc acaagcctaa
     3841 aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg aagtggacac
     3901 cgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata tgattatcga
     3961 gcgtctcaag gctaccaagg ttcctgtgat tttggtggtg aataaaatcg ataaggtcca
     4021 tccagaccag ctcttgtctc agattgatga cttccgtaat caaatagact ttaaggaaat
     4081 tgttccaatc tcagcccttc agggaaataa tatgtctcgt ctagtggata ttttgagtga
     4141 aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagatc atccagaacg
     4201 tttcttagtt tcagaaatgg ttcgcgagaa agtcttgcac ctaactcgtg aagagattcc
     4261 gcattctgta gcagtagttg ttgactgtat gaaacgagac gaagagacag acaaggttca
     4321 catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca tcggtaaagg
     4381 tggcgctatg cttaagaaaa tcggtagtat ggcccgtcgt gatatcgaac tcatgctagg
     4441 agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg ataaaaagct
     4501 agatttggct gactttggct ataatgaaaa agaatactaa gtagaggtgg gctcatgcct
     4561 gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg aaaccgtttg
     4621 tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa ttcgctaccc
     4681 caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgactagtc agattatcga
     4741 gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg tcttgatttc
     4801 ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg aacgcaagca
     4861 tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg atgttcgcaa
     4921 gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta tttctaaaaa
     4981 attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat ctgcccttgc
     5041 caagtccaaa aagcctatca aatcccatct cctcgaccag accttggtag ctggacttgg
     5101 caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta gaccttccca
     5161 gactttgaca gcagaagaag cgacagctat tcatgaccaa accattgctg ttttgagcca
     5221 ggctgttgaa aaaggcggtt ccaccattcg gacctatacc aatgcctttg gggaagatgg
     5281 aagcatgcag gactttcatc aggtctatga caaggctggt caagcatgtt cacgctgtgg
     5341 gacagtgatt gagaaattcc agctcggtgg acgtggaacc cacttttgtc caaactgtca
     5401 aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc tggtaagtca
     5461 actgtgacaa attttctaag aaagcaaggc tttcaagtag tggatgccga cgcagtcgtc
     5521 caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca ctttgggcaa
     5581 gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct catcttttca
     5641 aatcctgaag agcaaaaatg gtcgaagcaa attcaagggg agattatccg tgaggaactg
     5701 gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga tattccccta
     5761 ctttttgagc aagactacag cgattggttt gctgagactt ggttggtcta tgtggaccga
     5821 gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga agctgagtct
     5881 cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca ggttcttgat
     5941 aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga gggaggtagg
     6001 caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg gtaattttct
     6061 gacaggagcc agtatttctt tggttgtatc ttttatgtcc atcttcgtgg aaaatctagg
     6121 tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct ctgctatttc
     6181 cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc gaaaacccat
     6241 gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct ttgtcccaaa
     6301 tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt ttgttcctaa
     6361 tgaaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg ccttaggtac
     6421 tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg gctttatcgc
     6481 agaattattt ggcattcgta cagttttctt actggttggt agttttctat ttttagctgc
     6541 tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg aaaaggctat
     6601 tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca atctcttttt
     6661 aaccagtttt gtcatccaat tttcagctca atcgatcggc cctattttgg ctctttatgt
     6721 acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg tgtccagtat
     6781 gggcttttcc agtatgatga gtgcaggagt catgggcaag ctaggtgaca aggtgggcaa
     6841 tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc tctgtgccaa
     6901 tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggcttgg gaaccggtgc
     6961 cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg gcatttcgag
     7021 ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc ccatggcagg
     7081 ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacga gcctttgtgt
     7141 tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag taaaggaaat
     7201 ctagtgcgag taaaaatcaa tctcaaatgc tcctcttgtg gcagtatcaa ttacctaacc
     7261 agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg tcccaaggaa
     7321 agaaaagtaa ccctacatct tgaatctaag tagattttat ggta
//
LOCUS       DAVDHZ010000069         6853 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000069 DAVDHZ010000000
VERSION     DAVDHZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.070"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VUR46_002072"
     CDS             complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VUR46_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET5457424.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
     gene            complement(587..763)
                     /gene="secE"
                     /locus_tag="VUR46_002073"
     CDS             complement(587..763)
                     /gene="secE"
                     /locus_tag="VUR46_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET5457425.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VUR46_002074"
     CDS             complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VUR46_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5457426.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            complement(978..3173)
                     /locus_tag="VUR46_002075"
     CDS             complement(978..3173)
                     /locus_tag="VUR46_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET5457427.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            3299..4135
                     /locus_tag="VUR46_002076"
     CDS             3299..4135
                     /locus_tag="VUR46_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5457428.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVSQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VUR46_002077"
     CDS             complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VUR46_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET5457429.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(5387..6352)
                     /locus_tag="VUR46_002078"
     CDS             complement(5387..6352)
                     /locus_tag="VUR46_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET5457430.1"
                     /translation="MNMSNITIEDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDK
                     VLAGSLYTDTNEQGLTIPSSLLKNWNEQTGRNLTANDLIGKSVSASIVESAAEASKIA
                     QFQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVT
                     EELQKNKKYTVLSQQKVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQR
                     SKEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSI
                     TKVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            complement(6413..>6853)
                     /locus_tag="VUR46_002079"
     CDS             complement(6413..>6853)
                     /locus_tag="VUR46_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5457431.1"
                     /translation="ETGFDTYFYREYGRSLKGQLIRGKVSGRRYQRISLVAGLTNGEL
                     IAPMTYEETMTSDFFEAWFQNFLLPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLL
                     PLPPYSPEYNPIEKTWAHIKKNLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         2051 a         1477 c         1189 g         2136 t
ORIGIN      
        1 attctgcgat ttggtttagg tttacttctg caactgtgtc attaccaaac atagagataa
       61 tcattttcac tttgttatta tcaatttctg taatcttacc agtgtagtct gcaaaagcac
      121 catcaataat acgtacagtt tgaccaatct caacatcgaa atcaaattct tgaacagttt
      181 gtcccataga taccaaaatg tcacgaattt cttgttccaa taatggagtt ggttttgatc
      241 tgttcccgtg tgatccgaca aatcctgtaa catttggtgt gtttcgaaca acaaaccaag
      301 cttcatctgt catgaccatt tctacaagaa cataacctgg aaaacgattt tcttctactt
      361 cttttctctt tccatttttt tcaacttgca ctgtttgtgt tggaatttca acgcgtagaa
      421 tattatccaa catattgtag gtttgtgcac gttgtaatag attttctttc accttatttt
      481 cataaccaga ataagtttgt aaaacaaacc accctttatc aaaactatcc atgatatttc
      541 ctttcataaa tagaagattt ctagtgtaat taactccact aatcttctaa aaaatgttaa
      601 taaatcgaat caaacctgaa acaatcaact ggtcaaaaat gtaaataatt actacaaaga
      661 aagctgtgta ttccatgata gaacgaaaat ctctccagct ttccttgcga gttggccatg
      721 ttgtgtcttt aagaagtcta aaaatatctc caataaaacg catcgctctc tcctatctcg
      781 tttctctgtg tgtagtgtac ttgccacaat gcttacaaaa tttatttact tctagtcgtg
      841 taggcttggg gtttccgctg atcttgattg aatagtttct cgaaccacaa accgcacaag
      901 ctaggcttgc tttttttagt gccataacgc ctccatctta tccattataa caagaaagct
      961 aggctttgac aagcatctta gcgaaataga ttgactatcg aatcccatat tgtttgagcc
     1021 ttttccttaa tcttcgcatc tgagatagcc cggctagcct catctactag actttgcgca
     1081 cgccctcgaa tatcagacaa attatcatct gtctggctat tatcattggt ttgtacttgt
     1141 ctttttgtat tggctggtgc aattccattt tgcttataag cattttcaac cgtaaaggta
     1201 cttcctggcg tataaggtaa aatggtattg gcaatgtttc taaagacatg agctgcaccg
     1261 tttgaagtag agccagctag atagtgattt tcatcagtgg tcggaaagcc aagccagtgg
     1321 ctaatcacta catccggagt ataaccaatt acccactggt cacttgtgta ctccggatta
     1381 aaaactgctt cagttgttcc agtcttccct gccataatat agtctgcagg cgatgaacta
     1441 ataccggtac cgttggtgaa agtccccaac atcatactgg tcatcttgtc agctacagac
     1501 ttatcaatca cccgtttttg tgaattttta tgattcgcaa taacttgtcc actagcattt
     1561 tcaattctac taataaaatg agcttcaggc attaaacctt catttgcaaa ggcagcgtat
     1621 gcttgagcca tttgaagagg gttggtttca acaccgcttc ccaaggcgac accaagaaca
     1681 cggtcgacct tttccatgtt gagtccgaat ttttcgcctg cctcaaaagc cttgtcgaca
     1741 cccaaatcat taacagtggc aacagcaggt agattaagcg attctgccaa ggcttgatac
     1801 ataggaactt ctcgactcgt tttgatccct gcatagttat caaccttata gctgtcatac
     1861 tgcatggtat ggttatccaa ctgcttattc aaagcccagc ctgcttcaac tgctggcgta
     1921 taaacaacta aaggcttaat tgtagaacca ggactacgct ttgattgggt tgcatagttg
     1981 aaattccgga atccagtttt atcattgtca gcaacttgac cgacaactcc acgaactccc
     2041 cctgttttcg gttcgagagc tacacttcct gattgagcaa acgttccatc ctctgccctc
     2101 ggaaatagcg atgtgttttc ataaacaatc tgcatatttg cttggtagtt ttggtccagc
     2161 tctgtgtaaa tgcggtagcc attattgaca atctcttcct ctgttagatt atacttggaa
     2221 acagcttcat taaccaccgc atcaaaataa gaggggtaac ggtaatctga gatttttcct
     2281 tcatacttat cgtgcaattg cgaagtcata tcaacttcag cagcttcggt ttcttggttt
     2341 ttatcaatat atcctgctgc aaccatattc tgcaagacag tatcgcgccg attagtagaa
     2401 tcttctacgg aattcaaggg attatacagt tccggcccct tgagcatccc tgccagagtc
     2461 gcagcttgat ccagactcac ttctgatgca gaaactccaa agtatttctt actcgcatct
     2521 tctacacccc acacaccatt tccaaaataa gcgttgttaa ggtacatggt tagaatttgc
     2581 tccttactat attttttgct taattctaag gcaaggaaaa attctttcgc ttttctctca
     2641 acagtttgat cttgtgataa ataggcgttt ttagccagct gttgggtaat ggtagagcca
     2701 ccacctgaac gtccagcagt gacaatagcc aagaagaaac ggccatagtt aatcccgtca
     2761 tttttataga aagaacggtc ttctgtcgca ataacagcat tctgcaagtt tttactgata
     2821 tcagtcagct caacataggt tcccttttga ccagacaagg caccagcctc tttttcttca
     2881 cgatcaaaaa taagagtccg agttttcaag gcattttgca aatcattgac attggtcgac
     2941 ttagctacag caaacaaata gattccaact agcaagcctg cactcaaacc tagtataagg
     3001 ataatctttg ttagatgata acgacgccag aattttcgaa tcggacctac ttgggctaat
     3061 ttttttcgat cactacgaga gcgacgtaag atagtagaat cagagtcctc tagttcactt
     3121 gtttcttttt taaaaagaga aagaaatttc tcaaataatt tatctaattt catgcgttta
     3181 ttttatcatc ttcatcatag gaagacaaga atttagctat ttcctatcca aatagggctt
     3241 tttttgttac aatatctgta tgcaattcac atttacatta cccgcctctc tacctcaaat
     3301 gacggtaaag caattacttg aggaacaact cctcatccct agaaaaatcc gtcatttttt
     3361 gagaatcaag aaacatattt tgataaatca agaagaagtc cactggaacg aaatcgtaaa
     3421 tcctggagat gtttgccagt tgacttttga cgaggaagat tatccccaaa agacgatccc
     3481 ttggggcaac ccagacttag tgcaggaagt ttatcaagat caatacttga ttattgtaaa
     3541 caaaccagag gggatgaaaa cgcatggtaa tcaaccaaac gaaattgccc ttcttaacca
     3601 tgtcagtacc tatgttagcc aaacctgcta tgtcgttcat cgtctggaca tggaaaccag
     3661 tggcttagtt ctctttgcca aaaatccttt tatcctgccc attctcaatc gcttattgga
     3721 gaaaaaagag atttctagag aatattgggc tctagttgat ggaaatatca acagaaaaga
     3781 acttgttttc agagacaaaa ttggacgtga tcgccatgat cgtagaaaaa gaatagttga
     3841 tgcaaaaaat gggcaatatg ctgaaacgca tgtaagcaga ttaaagcaat tctcaaacaa
     3901 gacttccttg gctcattgca agctaaagac agggcgaacc catcagattc gtgtgcacct
     3961 tttgcatcat aatcttccta tcctgggaga ccctctctat aatagtaaat caaagacaag
     4021 ccggcttatg cttcatgcct tccgactttc ctttacccac ccacttactt tagagaagct
     4081 aactttcact accctttcaa atacatttga aaaagaatta aaaaagaatg gatgatcgtg
     4141 tcatccattt ttccgtataa aaaaacaaga ccacaaagcc ttgctttcta tcaactcaag
     4201 aattatttag caatttttgc gaagtattca agagtacgaa caagttgtgc agtgtatgac
     4261 atttcgttgt cgtaccatga tacaacttta accaattgtt taccgtcaac gtcaagaact
     4321 ttagtttgag ttgcgtcaaa caatgaaccg taagacatac ctacgatatc tgaagatacg
     4381 attggatctt ctgtgtaacc gtatgattcg tttgaagctg ctttcatagc tgcgttcact
     4441 tcatcaacag taacgttctt ttcaagaact gctaccaatt cagtaactga tccagttgga
     4501 gttggaacgc gttgtgcaga tccgtcaagt ttaccattca attctgggat tacaagaccg
     4561 atagcttttg cagcaccagt tgagttagga acgatgtttg cagcaccagc gcgagcacgg
     4621 cgaaggtcac caccacggtg tggtccgtca aggatcattt ggtcaccagt gtaagcgtgg
     4681 atagtagtca tcaatccttc aacaacacca aagttgtctt gaagagcttt agccattgga
     4741 gccaagcagt ttgtagtaca tgaagcacct gagataactg tttcagtacc gtcaagaacg
     4801 tcgtggttag tgttgaatac aactgtttta acgtcgtttc caccaggagc agtgataaca
     4861 acttttttag ctccaccttt aaggtgtttt tcagctgctt ctttcttagc aaagaaacca
     4921 gtagcttcaa gaacgatttc tacaccgtca gtagcccagt cgatttgttc tggatcacgt
     4981 tcagcagaaa ctttgatgaa tttaccgtta acttcaaatc caccttcttt aacttcaaca
     5041 gtaccgtcga aacgaccttg agttgtgtcg tatttcaaca agtgtgcaag cataactgga
     5101 tctgtaaggt cgttgatgcg tgtaacttca acaccttcta cgttttggat acgacggaaa
     5161 gcaagacgac cgatacgtcc gaaaccgtta ataccaactt taactaccat tagtgatttc
     5221 ctccttatga aaatcatgaa atttttattg tgaaaagagt aacttgaatc actacaaatc
     5281 acctttcaac aaacctatta tacaactatt tgagttgaat tgcaagtatg gccattgttt
     5341 ttctatgtta gtttcttttt aagactgtaa atcaaggaat cccttactat tcatagcgta
     5401 acgattctac aggatccatt ttactaatct tacgcgccgg gaagtaggct gagacataac
     5461 caagtaatag agcgaaaact agagttccta aaacagataa aagatttaat tcaaaaacct
     5521 tagtgatgga tgggtaaaag tgacttacaa tcgcattcgc caaacttccc accccttgtg
     5581 caaccaaaaa tgccagcagc aaggcgatgc ctacaatcca gatagcctcg taaataaaaa
     5641 ttcctttgac atcacgattc tgataaccaa ctgctttcat gacacctatt tccttggaac
     5701 gttgcatgat attgatgtaa ataatgatac caatcataac cgctgctacc acaatagctt
     5761 gtgatgaaag cacaatcaat aatccctgaa taacacgaat aaagataatc acaatatcaa
     5821 gaactttttg ttgagaaagc acagtatact tcttattttt ctgtaattct tctgttacta
     5881 cttttgtctg tgatggatct ttgagttcca agataaaata agatacagct ttcgtaaatc
     5941 cagcctcttt caaaatcgtt tccatttgat gagacagcat gaaactgttg ctgtcctcca
     6001 tgtcatcttc atcattgatt acacgtacaa tcttcgtttg aaattgagca atcttactag
     6061 cttcggcagc actttctaca atgctggctg agactgattt accaataaga tcattagctg
     6121 tcaaatttct tcctgtctgt tcattccaat tttttagtaa actgcttgga atcgttaatc
     6181 cctgttcatt tgtatcagta tagagggatc cagccaacac tttgtccgtc tcattattac
     6241 taacagagat acttgtatca tcataaagac tcactacttg agcataagaa ggcatcgttt
     6301 gactcagatc catttcttgc ccatcttcta tagtaatatt tgacatgttc atcccaaaag
     6361 gactctccaa ataattaata gcttctttcc caactgtatc cgtgaactat agtcaattga
     6421 aacaagaaca agagaaaaga gcctcgtaaa aggtattgca acttggtaat acctttttga
     6481 ggttcttttt gatatgagcc catgttttct caataggatt gtactcaggt gagtagggag
     6541 gaagaggtaa aagtttatgc ccaaactctt cgcataaaag ttctagcttc cccattctat
     6601 ggaatcttac attatccata ataataaccg atggtgtggt taatgttggt aagagaaaat
     6661 tctgaaacca agcttcaaaa aagtcgctcg tcatcgtctc ttcgtaagtc attggagcga
     6721 ttaattcacc atttgttaga cctgcaacca aagaaatcct ctgatatctt cttccagata
     6781 ctttgcctct tattaactga ccttttaatg agcgaccata ttctcgataa aaataagtat
     6841 cgaatcctgt ttc
//
LOCUS       DAVDHZ010000070         6506 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000070 DAVDHZ010000000
VERSION     DAVDHZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.071"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(1..724)
                     /locus_tag="VUR46_002080"
                     /pseudo
     CDS             complement(1..724)
                     /locus_tag="VUR46_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(946..1257)
                     /locus_tag="VUR46_002081"
     CDS             complement(946..1257)
                     /locus_tag="VUR46_002081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457432.1"
                     /translation="MKRIIKLTLTLAVSTLVLVGMANTVQADETNARVSTHQTMRKNP
                     FRLHFEKVVLEAYQAAAEMAKNNYDSYAQLDEEIRNAKEELTDGSRTLIEVASSTILF
                     R"
     gene            complement(1392..3665)
                     /locus_tag="VUR46_002082"
     CDS             complement(1392..3665)
                     /locus_tag="VUR46_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000909941.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET5457433.1"
                     /translation="MSKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATENVSAN
                     PPIPQIVSPGDKKEYEDAVQRVNKEISDYVTSRLDSLDRSVSGFSEIVTKVQVVVDKY
                     RDKIDRVSTKSMVEELGREVKKKVDEEIKLFQNRSGSKSTPKGLSLNDGLQGGDPSVG
                     QGPGVVPQPGGQAGGSMVVPPVTQTPPSTSPSPGQKATEAEKKKLQDLIRQGQEELKK
                     LEDYLREVNNYPELPDNDPDYKVQKKDIWDNSKDTAPKKIQVFKEQLEKQTYTEKTLK
                     DAVAEFIYYQFHAQIETMTRKIATYRKKHPNVAEVERLFSEKLKQTANSTYATLEGEA
                     LKTYFERDFLPVFNKIHSIIEELEKKSSQGELKKQDKVAEAQKKVEEAEKKAKAQKEE
                     DRRNYPTNTSKTIELEIAEAQVEVAKAELELAQAQAQTPQDTDKINTAKAKVETAKSK
                     VKTLEKIKSDSGRAQAGDQKPSMPAPDTKPDLQPQPEVPSTSPEPKPIPQPDGKQPST
                     PKEPENKKPSVPTQEKPIPQPEKPKPEVKPQPETPKTSKIITASDGKTKVTVVFDKAV
                     DADKVNIKEVTTKELAEKIARQTGGGTVRIFDLSLSKGGKETHVNGERTVRLALGQTA
                     SDVHVYHVKENGDLERIPSKVENGQVVFKTNHFSLFAIKTLSKNQNVTTPKQIKPSVQ
                     HGQTQIGENQTGKFQNKEVNHKPLATGNETMAKENPTSATEKNLPSTGAATNLVLEII
                     GLLGLAGTSLIAMKRRK"
     gene            complement(3748..4275)
                     /locus_tag="VUR46_002083"
     CDS             complement(3748..4275)
                     /locus_tag="VUR46_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET5457434.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGQEFGVENTKRLT
                     FAHIIFYLSCFVEAMVHKTIFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKFVDHFLFRTVKHPNYFLNILPELVGLALVSHAYVTFIFIFPIYATILYHRIAEEE
                     KLLQEVIIPNGRMRG"
     gene            complement(4384..5724)
                     /locus_tag="VUR46_002084"
     CDS             complement(4384..5724)
                     /locus_tag="VUR46_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET5457435.1"
                     /translation="MIKNPKLLTKSFLRSFSLFGAIALIIHIAIYLTFPFYYIQQEGE
                     KFNESATIMVKYLEGKKIQELPSLLESYSKSLRRSAHLKDDVLDKRISLVHDLEIKEG
                     SPTSYIVTIDRQITTADGKKVTIQFIQGVDIYKEATRIMFLYLPYTFLATLVFAFLFS
                     YFYTKRLLEPLFYISKITSKMQELDHNIRFNEMRKDEVGEVGKQINDVYENLLRVIDE
                     SERRNERIVRLQNQKVSFVRGASHELKTPLASLRIILENMQYNIGDYKDHPKYIARSI
                     NTIDQMSHLLEEVLESSKFQEWTECRETLTVKTVLVDILSRYQELAHSRGVTIENQLT
                     DATRVSMSLKALDKVLTNLISNAIKYSDQNGCVMISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKAEGSGLGLYIVNNILESYQMDYSFLPYERGMEFKIDLQID"
     gene            complement(5721..6374)
                     /gene="bgrR"
                     /locus_tag="VUR46_002085"
     CDS             complement(5721..6374)
                     /gene="bgrR"
                     /locus_tag="VUR46_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor BgrR"
                     /protein_id="HET5457436.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIVAKDGQEALEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINRNHDIPVIVLSALGDEETQMQVFDLYADDHVTKPF
                     SLVVLVKRIQALLRRYYVVEDIWHYQDVTVDFTSYQARVKNEEVAIKPKELLVLKCLI
                     QHKNQILSRKQILESISNDFADLPLDRVVDVYIRNLRKKLDLDCIVTVKNVGYKISL"
BASE COUNT         1822 a         1346 c         1110 g         2228 t
ORIGIN      
        1 tgaaaaatcc tccttgactt tacgcaagac tttcttgagt ttccgacgtt gggttttacg
       61 ctcatccttc cctttaatag ctgtctcctc aatgtcctgg ttcaggtttt ccaattcttc
      121 ttcaaggact tgagcgaatg caagcaactg ctctgagggg ataggctctt cttcctccaa
      181 cttaatggcc tgatggataa ggggagtgat ttcttcttga aaatagactt gtatctgttc
      241 ttgaagtttg gcggcaaact tgtccgttgc tttcttccac acgaaactat acttattggc
      301 attggcttca atcttagtcc cgtcaataaa caagcaatct aaggtcacga actcttccat
      361 ttttaaacga agattgaggt cgatgaaaag attgcgaatg agttcttcca tcccttcagc
      421 tacacgaaaa cgattgatgg tgcgatagct gacaaccaac tgccctgtta ggtattgcat
      481 agccagattt ttaatcatca ttttttcaat ttttcgtcca gagaaaatcc cttgtgaata
      541 ggcaaataga agagcagata caagcatttt agggtgataa gacgggcgac caaaggcatg
      601 atagaaggtg tggaagtaag gtattcacca ctttttcaat agtaaagacg agatggtctt
      661 gcggcaagaa ggaactgatt tctagtggta aagttgtttg atttatgtta tagtgaatat
      721 gcatgggata gcctttctaa atggtttatt gggcaattct attttaccaa gactatcgca
      781 accatgcaaa aaaaagcaac ggcaaatccg ttgctttttt tggagataag agacttttgt
      841 cccaggctct ttaattttgt catctgtaac tacatatagg gtcttcgtga agcttattta
      901 gttgactggt attcactaaa gtctttattt acacgattaa caaaatcatc taaagaggat
      961 tgtgctactt gctacttcaa tcagtgtacg cgagccatca gtcaattcct ctttagcatt
     1021 acgaatttct tcatctagtt gtgcatagga atcatagtta tttttagcca tttcagccgc
     1081 agcttgataa gcctctaaaa caactttttc aaaatgcaaa cggaatgggt tcttacgcat
     1141 cgtttgatga gtagatacac gagcattggt ttcgtctgct tggacagtat ttgccattcc
     1201 tacaagtacc aacgttgata cagctaatgt taatgttaat ttgattatac gtttcatatc
     1261 aaaacttcta tcttataaaa attgggttaa aacggataga taccatgtat aatagatatc
     1321 cttactagat tggggttctg cccaatctag catcaaacat ctaatacaga ttcttttgaa
     1381 aaatgtagtc attattttct tcttttcatc gcgattaatg aagttccagc caaaccaagg
     1441 agaccaatga tttcaagaac taaattagtt gctgcccctg tggatggcaa attcttctca
     1501 gttgctgatg taggattttc ttttgccatt gtttcatttc cagtagccag tggtttatga
     1561 ttaacttctt tattctggaa ttttccagtt tggttttctc ctatctgtgt ttgaccatgt
     1621 tggacagaag gtttaatctg cttaggtgtg gtgacatttt gattcttaga aagtgtctta
     1681 atcgcaaaca aactgaagtg gttggtttta aagacaactt gcccattttc aactttagaa
     1741 ggaatacgct caaggtcacc attttccttt acgtgataga cgtgaacatc tgatgcagtc
     1801 tgcccaagcg ccagcctaac agttcgttct ccattgacat gagtttcctt gcctccttta
     1861 gataaagaaa gatcaaagat gcgaacagtt cctccaccag tttggcgagc gattttttca
     1921 gccaactcct tcgtcgtcac ttcctttata tttaccttat cagcatcaac agccttatca
     1981 aatacaaccg taaccttagt tttcccgtca gaagctgtaa tgatttttga agtttttggg
     2041 gtttctggtt gtggtttaac ctctggtttt ggtttttctg gttgtggaat cggcttttcc
     2101 tgtgttggaa cagacggttt tttgttctcc ggttctttcg gtgtacttgg ttgcttaccg
     2161 tctggctgtg ggattggttt aggttccgga cttgtactcg gaacttctgg ctgaggttga
     2221 aggtctggtt tggtatccgg ggctggcatt gaaggttttt gatcacctgc ttgcgctctt
     2281 ccactgtctg atttaatttt ttctagggtt ttaaccttgc tcttagctgt ttctaccttg
     2341 gctttagcag tattaatttt gtcagtatct tgaggtgttt gggcttgagc ttgtgcaagc
     2401 tcgagctctg cctttgcgac ttctacttgt gcttccgcaa tttccagttc gattgtttta
     2461 ctagtattgg ttgggtagtt acggcgatct tcttcttttt gagccttggc ttttttctca
     2521 gcctcttcaa ccttcttctg agcttctgct accttgtcct gtttcttgag ctctccctga
     2581 cttgatttct tttctagttc ctcgataata ctgtggattt tgttaaagac cggtaaaaag
     2641 tctctttcaa aatacgtttt caaggcttcc ccctctaagg tagcataagt actgttagcc
     2701 gtttgtttta gcttttcaga aaatagtctt tcaacttcag ccacattagg atgttttttt
     2761 ctatatgtgg ctatctttct agtcatcgtc tcaatttgtg catgaaattg ataatagata
     2821 aattcagcaa cagcatcttt taaagttttt tctgtatagg tctgtttttc aagctgttct
     2881 ttgaatacct ggattttctt aggcgcagta tccttactat tatcccaaat atcttttttc
     2941 tgcactttgt aatctggatc attatccggt agctctggat agttattgac ttctctgaga
     3001 tagtcctcta gctttttcaa ttcttcttgg ccttgacgaa tcaagtcttg taactttttc
     3061 ttttcagctt cggtcgcctt ttgtcctgga cttggggaag ttgatggagg tgtttgcgtc
     3121 accggtggta caaccattga accgcctgct tgtcctcctg gttggggtac gactccaggt
     3181 ccttgtccta ctgaagggtc acccccctgt aaaccatcat ttagagagag ccctttagga
     3241 gtacttttac tacctgaacg attttgaaat aactttattt cttcatctac ttttttctta
     3301 acttcccttc ccagctcctc taccatgctt ttagtagaaa ctctatcaat cttatctctg
     3361 tatttatcta caaccacctg aacctttgtg acaatttctg aaaatccaga aacagatcga
     3421 tccagtgagt ctaaacgact agtcacatag tccgaaattt ctttgttaac tctttgtaca
     3481 gcatcctcat attctttttt atcacctgga gatactattt gtggaatagg gggattagca
     3541 gaaacattct ctgtcgcatg aaccacactt cccataaaaa gactggcaac agctacacta
     3601 gccactccta cactaaattt gcgaatagaa taacgcattc ttctttcatg atttgattta
     3661 gacatatcta tatcctccat aattttaact aactacagta tatcctgcta atatgaattg
     3721 tatatgaaat ttgctacatt attttcgcta tcctctcatt cttccatttg gaataataac
     3781 ttcctgcagt aatttctctt cctctgctat tctatggtat aaaatagtag catatatagg
     3841 aaaaataaag atgaatgtca cgtaagcatg gctcactagg gctaaaccaa ctagttcagg
     3901 taatatattt aaaaagtaat taggatgctt tacagttcta aaaaggaagt gatctacaaa
     3961 tttgtgatta ttgacaagca taagctttac tgtccaaata tctcccaaca agtgaatcac
     4021 caacatcaac atcagcatag aaaaaataag caaaactaaa ccaaccatgc tcatgccatc
     4081 aaaaattgtc ttgtgcacca tcgcctcaac aaagcaagag agatagaaaa taatatgtgc
     4141 aaacgtcaat cgttttgtat tttcaacccc gaattcttgc ccaccattgc taaggatccg
     4201 tttctcattc tctattgaac gttttaaaaa aatcaatcga ataaggaatg ttactaaaat
     4261 aattgctaat accatattag tatcctttct tttatctata caaaggataa cacccctatg
     4321 ttaaccctat atgaactgta acaaaaaaga acggaatact ttccgttcct gctatttgag
     4381 cacctaatct atctgcaagt caatcttaaa ctccataccg cgttcatagg ggagaaaact
     4441 ataatccatt tgataacttt ctaaaatatt attcacaatg taaagaccca aaccggaacc
     4501 ttcagcctta tctgttacga tttgagaatg atagaatata tcaaataaat gctctagttc
     4561 ttggtcactt agaggcgcac atgtattttt gattgagaga tagccatctt gctcagatat
     4621 catcacacag ccattttgat ctgaatattt gatagcatta ctaatcaggt ttgttaaaac
     4681 cttatctaat gctttcagac tcatgctaac tcttgtagca tctgtcaatt gattttcaat
     4741 tgtaacgcct cttgaatgag ctaattcttg ataacgtgat aaaatatcta ctaaaactgt
     4801 tttcacagtc aaggtctcac gacactctgt ccattcttga aatttagaag actccaatac
     4861 ttcttctaac aggtggctca tctggtcaat cgtatttata ctccttgcta tatacttagg
     4921 atgatcttta taatccccaa tattgtactg catattttct agaataattc gaagactggc
     4981 taaaggggtt ttcaactcat gtgatgctcc acgaacaaaa gaaactttct gattttgcaa
     5041 cctgacaatc cgttcatttc ttctctctga ttcatcaatg actctcagta agttttcata
     5101 cacatcattg atttgctttc caacttcccc aacttcatcc tttcgcattt cattaaagcg
     5161 aatattatga tccaactcct gcatcttact tgtaattttt gatatataaa agagaggctc
     5221 caataaacgt ttcgtataga agtaggaaaa gagaaaggca aatacaagcg ttgctagaaa
     5281 ggtataaggg agatagagaa acataattcg tgttgcctct ttataaatat ccacaccttg
     5341 aataaattga atggttacct ttttaccatc agccgtcgta atctgacgat caattgttac
     5401 gatatagcta gtgggacttc cttcctttat ttccaagtcg tgcacaaggg aaattctctt
     5461 atccagtaca tcatctttca aatgggcaga tctgcgaaga gacttcgaat aggattccag
     5521 caaactaggc agttcctgaa tctttttccc ttccaaatat ttgaccataa tagtcgcact
     5581 ctcattaaac ttctcacctt cttgctgaat gtaataaaaa ggaaaggtca gatagatagc
     5641 aatgtggata atcaaagcaa ttgcaccaaa aagcgaaaaa cttcttaaaa atgatttggt
     5701 taataattta ggatttttta tcataagcta attttatatc cgacattttt cactgttaca
     5761 atgcaatcca gatccaactt cttacgaaga tttcgaatgt aaacatcaac tactctatca
     5821 agaggcaaat ctgcaaaatc atttgagata gactcgagta tctgctttct actcaaaatc
     5881 tggttcttat gttgaatcaa acattttaaa accaacaatt ctttcggctt aatcgcaacc
     5941 tcctcgttct taactcgagc ttggtaggat gtgaaatcca ctgtcacatc ctgataatgc
     6001 caaatatcct ccacaacata gtaacgccta agcaaggctt gaatacgctt gactaggact
     6061 accagtgaaa atggtttcgt cacatggtca tcagcataaa ggtcaaatac ctgcatctga
     6121 gtttcctcat ctccgagcgc acttaaaaca atcacaggaa tatcatgatt tctattaatt
     6181 tcttttaaca cttcaaaacc actcttccta ggcatcatta aatccagtac catgagatgg
     6241 atagggagat cttgaaattt ttccaaggcc tcctgtccat ccttagccac aatgacatga
     6301 taaccctctt ctgtcagaaa tgctgcaatt ccttctctaa tcatttcctc gtcatctgca
     6361 actaaaatgt tcatccattc cccttcttaa cctatctaag attcactctt ttgctaggtt
     6421 tacattattt ccatttcgta cgtaaaaaag aaacagggct ctattgaaat ggtggaaatt
     6481 tcaggaaact ctgctctttt tcattc
//
LOCUS       DAVDHZ010000071         6115 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000071 DAVDHZ010000000
VERSION     DAVDHZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.072"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>6115
                     /locus_tag="VUR46_002086"
     CDS             <1..>6115
                     /locus_tag="VUR46_002086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457437.1"
                     /translation="GGEFTNRINPTDGRRYINYNAKSHFQLNNLRAYWEHSSGANGST
                     YSSVIRDWNTRYLGKKREKLMVRYPSDDGIYRSNRDDGGGRYEILDGTFIVKPVKPSI
                     QTSLGKVGKNTLTVNNVNSGTTVVAYDMANPRIPREIGRVSVPKDGDYRIKNGIELTL
                     NSGEVLRKDQKIATKVIYEITNADQRTESDSSDTLTVKESLVANGIHVIKDETYTGNV
                     KDRIRYNDDTDADRRTAFPNNASASWVQNPDYSRLGTRNYSANVRIPGQGDARVDVPV
                     HVYAPASLKASSYNNKQGTLSNGTEAENYIQFRDGNATIDKPNNVTVRWKDGQAPDVS
                     RPGTQQKTIEVVYPGNDGPSSTVIREYQVTFTSYHAQAQKREYTRTIGENFTSTTAKS
                     YVKKADGSPELPQETEYAWKKDETANREYGSETWGKVNDDWLGKKTNKIKVYYPNADG
                     GNNKADNLAEETEEITFITKPAKPRIASNLTGQAGTRSNVVIQNATPGTTLELRDGDT
                     VLGKVEVPKNNSLYSQLTTATITPTADIPASANITVKSIYSPNNQDQRVESDSSDAVA
                     STQITVSAKGTIQTLAGTGHIAGLSNLNKATLSTLLNLSDGSAVADGTTGRWESGQNI
                     AKGQAGTRTEKLFVRLPGHTKEQEVTFTVKTLAVPSAKAVVKDKGQDIVADDLSNYVT
                     VEGQTGLSWKGNPSKVEVGKTLPKIKVTYPRAGQNGIAVTDIQDQEVDAKVYSLEVNG
                     VAKTRVTVGETFDPVAADYVTQVANTETLPSGVSYAWKNGNKPSSARVGKETYTVETS
                     FGIGNDVPAELRGQKVETQVEVTVLSTKPSQPELGQNRNDLAITAVVGKENANKAVIT
                     FRDDADQEQTVTFEKGANNQWDKVGGINQPTVQILNNNDGTAIVHLTAGTAKVGSSVS
                     IKQQKADSDYSEAATLVAKERLDGVSATSKDDGSVDVVVPSEAKKASVTYTPEGQSQA
                     KTVELAKAQDGTWSAPANSGLLVNKDNTTGILTITVPASQVVDGSKVVGNADSDSKLS
                     IDAEARAKAPQPVEFDSSIRHNGDIVLTLPNNADTATINYPVSDTELKTATATKGQDG
                     SWRLSPDSGLELASTNGVTKITLAYTKLSGNRTVTASAKAGSGEGESKERTFTKTVPA
                     HTTPTTQNVVIAANATPTDDQLLTGVIANNKQSVAAKQTQTAIAAGTTKEIPATLTYT
                     DGSTEEITITVQSKPTAPTVNGLESRARVAVPGLLSTARTITGQAMQGAEKVKLTLQN
                     GSEKEVDVAADGSWSYTLAADEFLTQTISNSNAKYSSTKIRLVQVKDGLESEPKDIDI
                     LMGRATIDTPLRAGRDITLHIPHDTTSGYIRIGGSVERGGVDIGLKKVNGVWTLDTDA
                     NRASKLELVSETDPTNPALTKVTLKVKATDNASYSPPFTIGGDSGNVKFRAHYYSGRD
                     IGAVVPMGRQGQFEWILSGQPTNTRPTVGWETGKEIQDGQKIPSPTVDELKDFFKGED
                     AEDDAGLTVGYSASNRGKLRVRLYTSGTNQTVRTNVRGRIDPGNYRLLLSTIDAAGVE
                     SNILERNVIIQSYADYYRDAVQYPTTAQKVTYSDTDITNGNFTAAAKTRFKDKIETIN
                     RQNTQLPTSVTYSVGTTDDKAKVAVINFPDGSTIDISHSQVAKPDVPTITPTDTEQQG
                     MPKVTDADREISGTALQNATKVTLKLQTGKGIEIVKEITVNNTKDFAALVPGEGLLKN
                     GVWKYKLADGQYLRQTDATAEPGSSSLPLKATQTVFDAVSDDTSIYVANKRTVEGKKI
                     EGEVGSPDLKKYIDKPQDAVVYKEKGQEKPFPSDFIAKWENTPNFDTVGTFTYKVKFY
                     EKDGNTPADHISEGVEVTFVVKSKAPAILDYTNRDNGETLVNIPQDADEVVFSILRSD
                     TAVDTITVKKSEGWTATGIQKRDNTWVFPANSVHGNRTVTAVATAGKGDTKSVEMLTL
                     ITTLAHDVTVNEITKPTKGNPTSQDLLDAVEVTNKKSVALKQGENYPETFGTHQIHLI
                     VTYQDDSTEEKVANYTVPDTRD"
BASE COUNT         2086 a         1174 c         1412 g         1443 t
ORIGIN      
        1 ggtggggagt ttaccaatcg tataaatcct acggatggta gacgctatat taactataat
       61 gcaaagtctc attttcaact aaataacttg cgtgcttact gggaacattc ttctggtgca
      121 aatggctcaa cctattcctc tgttattcga gattggaata ctcgttattt aggtaagaaa
      181 cgtgagaaat tgatggttcg ctatccaagt gatgatggca tctatcgtag taatagagac
      241 gacggcggtg gacgatatga aatactagat ggaactttca tcgttaagcc agtcaaacca
      301 agcattcaaa ccagtcttgg caaggtagga aaaaataccc tgactgtcaa taatgtcaat
      361 agtggaacaa cagttgttgc ttacgacatg gcaaatccta ggattcctcg tgaaattgga
      421 cgtgtatcag ttccaaaaga cggggattac aggattaaaa atgggattga gcttacgctt
      481 aactctggtg aggtcttacg aaaagatcaa aaaattgcga ctaaagttat ctatgagatt
      541 acaaacgctg accaacgcac agagtcagat agtagtgata ccctgaccgt caaggaaagt
      601 ttggtagcta atggaattca tgtcatcaag gatgaaactt acacaggcaa tgtcaaagac
      661 cgcattcgtt acaatgacga tacggacgct gatcgccgca cagcgttccc taataatgca
      721 agtgcgagct gggtacaaaa tccagactat agtagattag gtacacgtaa ctacagtgcc
      781 aatgtaagga ttccaggtca aggagacgct agggttgatg taccagttca tgtctatgcg
      841 ccagcgagtc tgaaagcaag ctcttacaat aacaaacaag gtactctatc taatggtaca
      901 gaagcagaaa actatatcca atttagagat ggcaatgcaa cgattgataa accaaataat
      961 gtcactgtgc gttggaaaga tggacaagct ccagatgttt cacgaccagg aactcaacaa
     1021 aaaacaatag aagttgttta cccaggcaat gacggaccta gctcaacagt catcagagag
     1081 tatcaagtga cgtttactag ctatcatgca caagctcaga aaagggaata tactcgtaca
     1141 attggggaaa actttacctc aaccacagct aagagctatg tcaaaaaggc agatggttcg
     1201 cctgagttgc cgcaagaaac agagtacgct tggaagaagg atgagacagc taatagagag
     1261 tatggttcgg aaacatgggg caaggtgaat gatgactggc tcggtaagaa gaccaataag
     1321 attaaagttt actatccaaa tgcggatgga ggcaataaca aggcagataa tctagctgaa
     1381 gaaaccgaag aaattacctt tattacgaaa ccagctaaac caagaattgc aagcaatttg
     1441 acaggtcaag caggcacacg ttcaaacgta gtgattcaga atgcgacacc aggaacaacg
     1501 cttgaattgc gtgatggtga tactgtttta ggtaaggttg aagttccgaa aaacaatagt
     1561 ttatacagtc aattgacaac cgcaactatt acgcctacgg ctgatatccc tgcttcagcg
     1621 aatatcactg tcaagtctat ctattcacca aataatcagg atcaacgtgt ggagtctgac
     1681 agtagcgatg cagtagcaag tacccagatt actgtgtctg caaaaggaac cattcaaacc
     1741 ttggcaggaa cgggtcatat tgctggtttg agcaacctca ataaggcaac gctttctacc
     1801 ttactcaatc tttcagacgg aagtgcggtc gctgatggca caacaggacg ttgggaatct
     1861 ggtcaaaaca ttgccaaagg tcaggcaggc acacgaactg aaaaactctt tgttcgcttg
     1921 cctggtcata caaaagagca agaagtaact tttacagtca agacgctagc tgttccgagc
     1981 gctaaagcag ttgtgaaaga caaaggacaa gatatcgttg cagacgactt gagcaactat
     2041 gttacagtag aaggacaaac tggactcagt tggaaaggaa atccaagtaa agtagaggtt
     2101 gggaaaactc ttccaaaaat caaggtaacc tatccaagag ctggtcaaaa cgggatagcc
     2161 gtgacagata ttcaggatca agaggtagat gctaaggtat acagcctaga agttaatggt
     2221 gttgccaaga caagagtaac tgtaggtgaa acatttgatc cagttgctgc tgactacgtc
     2281 acacaggtag ccaatacaga aactcttcca tcaggtgtta gctatgcatg gaagaatggc
     2341 aataagccaa gttcggctag agtagggaaa gagacctaca cggtagagac aagcttcggt
     2401 ataggaaatg atgtccctgc agaacttcgt ggtcaaaaag ttgaaacgca ggtcgaagtg
     2461 acagtccttt ctactaaacc aagtcagcca gaacttggtc aaaaccgtaa tgatttagca
     2521 atcacagcgg ttgtcggaaa agaaaatgcc aataaggcag taatcacgtt tagagatgat
     2581 gctgatcagg aacagactgt gacctttgaa aaaggggcta acaatcaatg ggataaggtt
     2641 ggaggaatta atcaaccgac agttcaaatt ctaaataata atgatggaac agctatagtt
     2701 cacttgacag caggtacagc taaagtcggt agttctgtaa gcatcaaaca gcaaaaagca
     2761 gattcggact acagtgaagc tgcaacttta gtagctaaag aacgtttgga tggtgtcagc
     2821 gcgacaagta aagacgatgg ttcggtagat gtcgttgtac caagtgaagc caagaaggct
     2881 tctgtgacgt atactccaga aggtcaaagt caagcgaaga cagttgagtt agccaaggct
     2941 caagacggca catggtcagc gccggcgaat tcaggtcttc tagttaataa agacaacaca
     3001 acaggcattc tgaccattac ggttccagca agccaagtag tagacggtag taaggttgta
     3061 ggaaatgcag atagcgatag caagttgagt atagatgcag aagcgagagc gaaagcaccg
     3121 caacctgtcg aatttgatag ctctattcgt cataatggag atatagtgtt gacgctccca
     3181 aataatgcgg atacagcaac tatcaactat ccagtgagtg atacagagct gaaaactgct
     3241 actgcaacta aggggcaaga cggtagctgg aggctttcac ctgactcagg tcttgagctt
     3301 gctagcacaa atggagtcac taagataacg ctagcatata caaaattgag tggcaatcgt
     3361 acagtgactg caagtgctaa agcaggaagt ggtgagggag agagtaaaga gcgtaccttt
     3421 actaaaacag ttccagcaca cacaactccg acaacccaaa acgttgtcat cgctgcaaat
     3481 gcgacaccaa ctgatgacca attattgaca ggtgtaatag ctaacaataa acaatccgtc
     3541 gcagctaaac aaacacaaac tgctattgct gcaggaacta caaaagaaat tccagcaact
     3601 ttgacctaca cggatggttc gactgaagaa atcactataa cggttcagtc taagccgaca
     3661 gcaccgacgg tgaatggttt agaaagtcgt gcaagggttg ccgtaccggg tcttttatca
     3721 actgctcgca cgattacagg tcaggctatg cagggtgcag aaaaagttaa attaacttta
     3781 caaaatggta gtgagaaaga agtagatgtg gctgccgatg gtagttggtc ttatacgctt
     3841 gcagcagatg aattcctgac tcaaacaata tcaaatagta atgctaaata tagttctacg
     3901 aaaatccgtc ttgtgcaagt gaaagatggt ctagaatctg aaccaaaaga cattgacatt
     3961 ttgatggggc gcgccactat tgatacgcca cttcgagctg gacgtgatat cacccttcac
     4021 attccgcatg acaccacttc tggctatatc cgcataggag gttcggtaga acgaggtgga
     4081 gtagatatcg gactcaagaa ggtgaacggt gtctggactc ttgatacaga tgccaatagg
     4141 gcaagtaagt tagaacttgt gagtgagaca gacccgacga atccagcttt gaccaaggtt
     4201 acgctcaaag ttaaagccac ggataatgcc tcgtacagtc caccgtttac cattggaggt
     4261 gacagtggaa acgtgaaatt cagagctcac tattacagtg gtagagatat cggtgcagta
     4321 gttccgatgg ggagacaagg tcaatttgaa tggattttgt ctggtcaacc aaccaatact
     4381 agacctacag ttggctggga aactggtaaa gaaatccaag atggtcaaaa gattccatca
     4441 cctacagtag atgagttgaa agacttcttt aaaggggagg atgctgaaga tgatgcaggt
     4501 ctcactgtag gatactcagc ctctaataga ggtaaattac gtgttcgttt atatacaagt
     4561 ggaacgaacc aaactgttag aacaaatgtc cgaggacgaa tcgatccagg taattataga
     4621 ctgctcttgt ctactattga tgctgcaggg gtggagtcta atatccttga aagaaatgtc
     4681 atcattcaaa gttatgcaga ttactatcgt gacgctgttc agtatccaac tactgctcaa
     4741 aaggtaacct acagtgatac agatatcact aatggtaact tcacagcagc agccaaaaca
     4801 cgttttaagg ataaaataga gactatcaat cgccaaaata cccaacttcc aactagtgtg
     4861 acttatagcg taggaactac ggatgataag gcgaaagtag ctgtgattaa cttcccggat
     4921 ggttctacta ttgatatttc tcattcgcag gtagccaaac cagatgtacc gacaatcact
     4981 ccgacggata cagaacaaca ggggatgccg aaggtaactg atgctgatag agaaatttct
     5041 ggtactgccc ttcaaaatgc gacaaaagtg acattgaagt tgcaaactgg taaagggata
     5101 gagattgtaa aagaaattac agttaataat acaaaagatt tcgctgcctt agtaccagga
     5161 gaagggctct taaaaaatgg agtatggaag tataagctgg ctgacgggca atacttacgt
     5221 caaacagatg cgacagcaga accaggctcg tcctcactcc cattaaaagc aacacaaact
     5281 gtatttgatg cagttagtga tgatacgagt atctatgttg ccaataaacg tactgtagaa
     5341 ggtaaaaaaa ttgagggaga agttggcagt cctgacttga aaaaatacat agataaaccg
     5401 caagatgccg ttgtctataa agaaaaaggg caagaaaagc cattcccaag tgactttatt
     5461 gccaaatggg aaaatactcc taactttgat accgttggaa cctttaccta taaagtaaaa
     5521 ttttatgaaa aagacggcaa tacaccggct gatcacatta gtgaaggtgt tgaagttacc
     5581 tttgtagtca aatcaaaagc accagcaatc ttagactaca ctaatagaga taacggtgaa
     5641 actcttgtga atattccgca agatgctgat gaagttgttt tcagtatcct tagaagtgat
     5701 acagctgtag atactataac tgtaaaaaaa tctgaaggtt ggacggcaac agggattcaa
     5761 aaacgtgata acacttgggt atttccagct aactcagtac atggcaaccg aacagtaaca
     5821 gcagttgcga cagcagggaa gggtgatacc aagagtgtag agatgctgac attgattaca
     5881 acacttgctc atgatgttac tgttaatgaa attactaaac ctactaaagg aaatccaaca
     5941 tcccaagatt tgcttgatgc agtagaagta actaataaga aatccgtagc actgaaacaa
     6001 ggagaaaatt atccagaaac ttttggaact catcaaatcc acttgattgt aacctatcaa
     6061 gatgatagta cagaagagaa ggtagctaat tatacagttc cagatacaag agatg
//
LOCUS       DAVDHZ010000072         5772 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000072 DAVDHZ010000000
VERSION     DAVDHZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.073"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..586)
                     /gene="nth"
                     /locus_tag="VUR46_002087"
     CDS             complement(<1..586)
                     /gene="nth"
                     /locus_tag="VUR46_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET5457438.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNP"
     gene            complement(586..1128)
                     /locus_tag="VUR46_002088"
     CDS             complement(586..1128)
                     /locus_tag="VUR46_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET5457439.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVGDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1298..1615
                     /locus_tag="VUR46_002089"
     CDS             1298..1615
                     /locus_tag="VUR46_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET5457440.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            1854..2162
                     /locus_tag="VUR46_002090"
     CDS             1854..2162
                     /locus_tag="VUR46_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5457441.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKLYTTTSF
                     "
     gene            2210..3412
                     /locus_tag="VUR46_002091"
     CDS             2210..3412
                     /locus_tag="VUR46_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5457442.1"
                     /translation="MHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPS
                     NDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHL
                     DYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGRLLA
                     KKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLSIDD
                     RVLAQELRLTVRGQEKIGIIGPNGVGKSTLLAKLKQFLNDKREISLGFMPQDYHKKLQ
                     LDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLR
                     KPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTEHGL
                     ELVNLEDV"
     gene            complement(3456..4355)
                     /gene="htpX"
                     /locus_tag="VUR46_002092"
     CDS             complement(3456..4355)
                     /gene="htpX"
                     /locus_tag="VUR46_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET5457443.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(4357..4917)
                     /locus_tag="VUR46_002093"
     CDS             complement(4357..4917)
                     /locus_tag="VUR46_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET5457444.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPNNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            5011..5724
                     /gene="rsmG"
                     /locus_tag="VUR46_002094"
     CDS             5011..5724
                     /gene="rsmG"
                     /locus_tag="VUR46_002094"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET5457445.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFECYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
BASE COUNT         1821 a         1244 c         1081 g         1626 t
ORIGIN      
        1 ctggattttt tggatggcaa atggctcttc caaaataaat catggcctga tgggcagcta
       61 accactgctc aggcggcaag atatccatga cccgcttttc cacctcaagt ggcgtcgctg
      121 attttttgac aatatcgtgg tgtttgcaaa tacgctccac atgagtatcc actgcaaagg
      181 ctggaatccc aaatcctaca ctcatgacaa cattggctgt cttgcgacca acacctgcca
      241 aactctccaa ttcttcacgt gtctgaggga cttgaccatc aaaatcgtct agtaactgtt
      301 gggcacattt tttaaggaat ttagctttat tccgatacaa tcccaagcga gaaatatgtg
      361 aagcaatctc actctctgtc gctacagaca tagcttgggg tgttggaaag gcaacaaaga
      421 gacctggtgt ggccttattt accgctgcat ctgtcgtctg ggctgataac atgaccgcaa
      481 ccaggagttc aaaatgattg gtaaaatcaa gactaggctt ggcatctggg aagagggcaa
      541 tgatttcttc tagcaccttt cgtgctcgtt tttttgacaa gaccattatt catctccgtc
      601 aaatagtcct tgtaagccag caaaaggact gttttcttct ttctttactg cttgttgagc
      661 ttggtattct tcctctgtca tgatttgcca gtcatttcct gagacaaatc cttgaccagc
      721 ttcttcttca gccgtcaaga ccttgatagg aatgtttagc aggatattgt ctgatacact
      781 ctcagcaagg tcaagcgccc cattttcgat gggcaagacc aagtcatcat ctaaaacttc
      841 ttgatctagc tggttagttg cgccttccat gaaaacttcc gtgactggat aagattcaac
      901 taactcaact ggctccatac tgcgactcga agcaagaaca atggtataag atagttgata
      961 atctaagaaa tacatacggt cttcatattg tactttccca actgcaagga tatcttttac
     1021 atctaaaatt tcttgattac gtgcacgcag gtcaccaact aaatctaacg tttgttcaaa
     1081 gttcaaacct tcagactgct tacgaatttc ttgaatattt aatttcatac ttcctccata
     1141 aagatttact ctcttgatta taccatgaaa aggctacaaa tcagcacacc aaactttgta
     1201 attaaaattc aaaattttaa catatttact atgacagttt tgttttttag tgctatacta
     1261 tagggaaaga gtacatcaga tcaaggagga tgctcacatg gaagacaaga aactcattca
     1321 actcctatcc aagttaaata aaagctacca aaactgtaaa cagggtacgg cagatgatat
     1381 tcgactacaa gagctgctaa acactactat gcaagagctc aaaaaaacgg aaaagttgaa
     1441 caacagtatc ttaattgatc ttgagaaatt ttaccaaccc accagtcttc tgattggact
     1501 gggtagccta aaactaaacg atcaagcacg cactgcttgg cgaaactatg ataaattcca
     1561 ttacgagcat gtcaaacacg tactaagtct ctatggacct gtttttggat tttagagcat
     1621 agaatttcca gttttctgtt gacaaaattt ccttaaaggt ataatataaa gatactaata
     1681 ctcggaggta agggagacat gaacaactaa gtctatcaaa taaagaacct ttatttagta
     1741 gatcttgttt ttgtctcttt ttgtgtgctc ttttatgctc tttttctggc atgttaatag
     1801 agtttttttg acatagactt tgggatctac taggtaaagt agagcttttt gttatgcact
     1861 atgaacattc tagaaaggga aatcatatga taaaaatcaa tcacctgacc atcacacaaa
     1921 acaaagattt acgagacctt gtctctgacc taagcatgac catacaagac ggggaaaagg
     1981 tagctattat tggcgaagaa ggaaatggta aatcaacctt acttaaaact ttaatggggg
     2041 aagatttgtc tgatttcact atcaagggag acatccagtc tgattatcag tcactggcct
     2101 acattcctca aaaagtccct gaggacctaa aaaaaaaact ttacacgact acttcttttt
     2161 agattctatt gatttagact acagtatcct ctatcgtttg gcggaggaat tgcattttga
     2221 tagcaatcgt ttcgcaagtg accaagagat tggcaatcta tcagggggcg aagctttgaa
     2281 aattcagctt atccatgagt tagccaaacc ctttgagatt ctatttttag atgaaccttc
     2341 aaatgaccta gaccttgaga cagttgattg gctaaaaggc cagattcaaa agaccaggca
     2401 aaccgttatt ttcatttccc atgatgaaga ctttctttct gaaacggcag acactattgt
     2461 ccacttgcga ctggtcaaac accgtaaaga agcggaaacg ctagtagagc atttagacta
     2521 tgatagctat agtgagcaga gaaaggctaa ttttgccaaa caaagtcagc aagctgctaa
     2581 caaccaaaga gcctacgata aaaccatgga aaaacatcgg agagttaagc aaaatgtaga
     2641 aactgcgctt cgagctacca aagatagtac tgccggtcgc ctattggcta aaaagatgaa
     2701 aactgtcctc tcacaagaaa aacgctacga aaaggcagct cagtccatga ctcaaaagcc
     2761 acttgaagag gaacaaatcc aacttttctt ttcagacatc caaccattac cagcttctaa
     2821 agtcttagtc caactggaaa aagaaaattt gtccattgac gaccgtgttt tggctcagga
     2881 actgcgacta actgtccgtg ggcaagaaaa aatcggtatt atcggaccaa atggtgttgg
     2941 gaaatcaact ctgttagcca aattaaagca atttctgaat gataaaagag agatttccct
     3001 tggttttatg ccacaagatt accacaaaaa actgcaattg gatttatcct caatagctta
     3061 tatcagcaaa actggggaaa aagaggaact tcagaaaatc caatctcacc tagccagtct
     3121 caatttcagt tatccagaaa tgcagcatca aattcgctcc ttatctggcg gacaacaggg
     3181 aaaactcctg cttttggatt tagtcctgcg caaaccaaac tttctcctgc tggatgaacc
     3241 cacacgaaac ttttctccca cttctcaacc ccaaatcaga aaactctttg caacctatcc
     3301 aggcggtctc atcactgttt cgcatgaccg tcgtttctta aaagaggtct gttcaagcat
     3361 ctaccgcttg acagaacacg gtttggagtt agttaattta gaagatgtat aaatttgcaa
     3421 catagcaaaa atccagagac gacctctgga ttcttttaca tctgttttaa acgttcaatc
     3481 cgttctgaga taggtgggtg ggtataaaag agtttttgga accccccacc tttcttggga
     3541 tcattgatat aaagggcact gctagcatca tcgacgtggc gactcatagg tttgctattg
     3601 tccaacttat ctagggcatt aatcattccc tggggattgc gagtcagctc gacactagat
     3661 gcatctgcca gaaattccct ctgacgagaa atagcgagct gaaccaaggt tgcagcgaga
     3721 ggtgccagta caatagctag tagggaaacc actagcataa tgatttcaag accatttcca
     3781 tctcggtcat catcacttcg tctgcgacct gctccacccc accacatcat acgacctgcc
     3841 atactagaaa gcatggtgat agcactagca agggcaactg caatagtcga aatacggata
     3901 tcataattac gaatatgact aacttcatgt cccataacag cttctagttc ttcacgattc
     3961 atgatagcta gtagacctga agtcgcagca acagccgcat tttgaggatt agaacctgtc
     4021 gcaaaggcat ttaaggctgg atcatcaatg atgaaaacac ggggcatagg aatctgagcg
     4081 accagagcca tatcttccac tacatggtag aggtctggtg ccgtttgctc atccacctca
     4141 cgcgctccat tcatggacat gacaatctct gtcgattgaa aaatcataga caaagcgtag
     4201 ataaagccga taatcagtgc gataaccaaa ccaccaagtc cagatcttat aaagagataa
     4261 ccaaccgcat aaccaacaag agctaagagt aggaaaaata ccagcaacaa aatccaggtt
     4321 tttcgtttat tgcttgcaat ttgatcaaac aacatcttag tcacctaaac cgctaaaatc
     4381 aactttagga accgactttt cctcttcagg tgtttgaagg aaatctgccg ctttaaatcc
     4441 aaacattcca gcgataatat tgttcgggaa agtttctaat tttacattgt agttgctgac
     4501 aacactgtta tagagttgac gagagtaaga aattttattt tctgtgtttg tcaactcctc
     4561 ttgcaattta acaaagttag cactagcttt caaatctgga tagctttctg caactgcaaa
     4621 aatacctgaa acctgacgag tgagggcatc actggctttc atagcttctg ctggtgaagt
     4681 cgctgccgcc acttggttac gtagttctgc caccttttca agggtagaac cttcatattt
     4741 ggcataacct tttacagtct caatcaagtt tggcaagagg tcatttcgac gtttcaactg
     4801 aacatcaatc tgactccaag cctccttggt ttgcatacga tttttaacca aaccgttata
     4861 gctaacaatc acaaaaataa caataagagc gataactcca agaataatcc aagtcatgat
     4921 ataagtcctt tctactttta gattagtacc agtatatcaa atttttaatg attgtggtaa
     4981 aataagatga tactaaagaa ggaaataact atgaaaccaa aaacatttta caacttgctt
     5041 gccgagcaga atcttccact ttcggaccag caaaaagaac aatttgaatg ttattttgag
     5101 ctcttggtcg agtggaatga gaagattaat ttgacggcga ttacggacaa ggaagaagtt
     5161 tatctcaaac atttttacga ttcgattgca cccattcttc aaggtttgat tcccaatgaa
     5221 actatcaaac ttcttgatat cggggctggg gcaggatttc ctagtctacc aatgaaaatt
     5281 ctctatccgg agttagatgt gaccattatt gattcactca ataagcgcat caacttccta
     5341 caactcttgg ctcaagaact ggatttgaac ggagttcatt tctaccacgg acgtgccgaa
     5401 gattttgccc aagacaagaa cttccgtgct caatatgatt ttgtaacagc tcgtgcggtt
     5461 gcccgtatgc aggtcctatc tgaattgact attccctacc ttaaggttgg tggaaaacta
     5521 ttggcactca aggccagcaa tgcgcctgag gagttgttag aagctaagaa tgccctcaat
     5581 cttcttttta gtaaagtcga agacaatctc agctacgccc taccaaatag agatccgcgt
     5641 tacatcacag tggtagaaaa gaaaaaagaa acaccaaata aatatccacg taaggctggt
     5701 atgccaaata aacgcccgct ttaaattttt aagtaaaaaa atatttacaa aatcaacctc
     5761 gctctcttat tt
//
LOCUS       DAVDHZ010000073         5179 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000073 DAVDHZ010000000
VERSION     DAVDHZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5179
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.074"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            309..1854
                     /locus_tag="VUR46_002095"
     rRNA            309..1854
                     /locus_tag="VUR46_002095"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1906..1978
                     /locus_tag="VUR46_002096"
     tRNA            1906..1978
                     /locus_tag="VUR46_002096"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1939..1941,aa:Ala,seq:tgc)
     gene            2103..5004
                     /locus_tag="VUR46_002097"
     rRNA            2103..5004
                     /locus_tag="VUR46_002097"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5081..>5179
                     /gene="rrf"
                     /locus_tag="VUR46_002098"
     rRNA            5081..>5179
                     /gene="rrf"
                     /locus_tag="VUR46_002098"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1467 a         1049 c         1514 g         1149 t
ORIGIN      
        1 gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta cggactatgg
       61 tatgttgcgt caggaccact tgatgaaaaa aagtttaaaa aagcttaaaa atcttcaaaa
      121 aagtgttgac aagtgaaagt ggctgtgata tactaatata gttgtcgctt gagagaagca
      181 agtggcaaag acctttgaaa actgaacaag acgaaccaat gtgcagggcg ctacaacata
      241 agttgtagta ctgaacaatg aaaaaacaat aaatctgtca gtgacagaaa tgagtaagaa
      301 ctcaaacttt taatgagagt ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat
      361 acatgcaagt agaacgctga aggaggagct tgcttctctg gatgagttgc gaacgggtga
      421 gtaacgcgta ggtaacctgc ctggtagcgg gggataacta ttggaaacga tagctaatac
      481 cgcataagag tagatgttgc atgacatttg cttaaaaggt gcacttgcat cactaccaga
      541 tggacctgcg ttgtattagc tagttggtgg ggtaacggct caccaaggcg acgatacata
      601 gccgacctga gagggtgatc ggccacactg ggactgagac acggcccaga ctcctacggg
      661 aggcagcagt agggaatctt cggcaatgga cggaagtctg accgagcaac gccgcgtgag
      721 tgaagaaggt tttcggatcg taaagctctg ttgtaagaga agaacgagtg tgagagtgga
      781 aagttcacac tgtgacggta tcttaccaga aagggacggc taactacgtg ccagcagccg
      841 cggtaatacg taggtcccga gcgttgtccg gatttattgg gcgtaaagcg agcgcaggcg
      901 gttagataag tctgaagtta aaggctgtgg cttaaccata gtaggctttg gaaactgttt
      961 aacttgagtg caagagggga gagtggaatt ccatgtgtag cggtgaaatg cgtagatata
     1021 tggaggaaca ccagtggcga aagcggctct ctggcttgta actgacgctg aggctcgaaa
     1081 gcgtggggag caaacaggat tagataccct ggtagtccac gctgtaaacg atgagtgcta
     1141 ggtgttagac cctttccggg gtttagtgcc gtagctaacg cattaagcac tccgcctggg
     1201 gagtacgacc gcaaggttga aactcaaagg aattgacggg ggcccgcaca agcggtggag
     1261 catgtggttt aattcgaagc aacgcgaaga accttaccag gtcttgacat ccctctgacc
     1321 gctctagaga tagagctttc cttcgggaca gaggtgacag gtggtgcatg gttgtcgtca
     1381 gctcgtgtcg tgagatgttg ggttaagtcc cgcaacgagc gcaaccccta ttgttagttg
     1441 ccatcattta gttgggcact ctagcgagac tgccggtaat aaaccggagg aaggtgggga
     1501 tgacgtcaaa tcatcatgcc ccttatgacc tgggctacac acgtgctaca atggctggta
     1561 caacgagtcg caagccggtg acggcaagct aatctcttaa agccagtctc agttcggatt
     1621 gtaggctgca actcgcctac atgaagtcgg aatcgctagt aatcgcggat cagcacgccg
     1681 cggtgaatac gttcccgggc cttgtacaca ccgcccgtca caccacgaga gtttgtaaca
     1741 cccgaagtcg gtgaggtaac cgtaaggagc cagccgccta aggtgggata gatgattggg
     1801 gtgaagtcgt aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctttctaagg
     1861 ataaggaact gcgcattggt cttgtttagt cttgagaggt cttgtggggc cttagctcag
     1921 ctgggagagc gcctgctttg cacgcaggag gtcagcggtt cgatcccgct aggctccatt
     1981 ggtgagagat caccaagtaa tgcacattga aaattgaata tctatatcaa atagtaacaa
     2041 gaaaataaac cgaaaacgct gtagtattaa taagagttta tgactgaaag gtcagaaaat
     2101 aaggttaagt taataagggc gcacggtgga tgccttggca ctaggagccg aagaaggacg
     2161 tgacaaacga cgatatgcct tgggtagctg taagtaagcg atgatccagg gatttccgaa
     2221 tgggggaacc caacaggtaa tacctgttac ccacatctgt taaggatgtg aggaggaaga
     2281 cgcagtgaac tgaaacatct aagtagctgc aggaagagaa agcaaaagcg attgccttag
     2341 tagcggcgag cgaaacggca ggagggcaaa ccgaagagtt tactcttcgg ggttgtagga
     2401 ctgcaatgtg gactcaaaga ttatagaaga atgatttggg aagatcagcc aaagagagta
     2461 atagcctcgt atttaaaata gtctttgtac ttagcagtat cctgagtacg gcgggacacg
     2521 tgaaatcccg tcggaatctg ggaggaccat ctcccaaccc taaatactcc ctagtgaccg
     2581 atagtgaacc agtaccgtga gggaaaggtg aaaagcaccc cgggagggga gtgaaataga
     2641 acctgaaacc gtgtgcctac aacaagttcg agcccgttaa tgggtgagag cgtgcctttt
     2701 gtagaatgaa ccggcgagtt acgttatgat gcgaggttaa gttgaagaga cggagccgta
     2761 gggaaaccga gtctgaatag ggcgccttag tatcatgacg tagacccgaa accatgtgac
     2821 ctacccatga gcaggttgaa ggtgcggtaa gacgcactgg aggaccgaac cagggcacgt
     2881 tgaaaagtgc ttggatgact tgtgggtagc ggagaaattc caaacgaact tggagatagc
     2941 tggttctctc cgaaatagct ttagggctag cgtcgacatt agagattctt ggaggtagag
     3001 cactgtttgg gtgaggggtc catcccggat taccaatctc agataaactc cgaatgccaa
     3061 tgaattatgg tcggcagtca gactgcgagt gctaagatcc gtagtcgaaa gggaaacagc
     3121 ccagaccacc agctaaggtc ccaaaataat tgttaagtgg aaaaggatgt ggggttgcac
     3181 agacaactag gatgttagct tagaagcagc tattcattca aagagtgcgt aatagctcac
     3241 tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa acaatttacc gaagctgtgg
     3301 atacctttat aggtatggta ggagagcgtt ctatgtgtga tgaaggtata ccgtgaggag
     3361 tactggaacg catagaagtg agaatgccgg tatgagtagc gaaagacagg tgagaatcct
     3421 gtccaccgta agactaaggt ttccagggga aggctcgtcc gccctgggtt agtcgggacc
     3481 taaggagaga ccgaaaggtg tatccgatgg acaacaggtt gatattcctg tactagagta
     3541 tgtagtgatg gagggacgca gtaggctaac taaagcagac gattggaaga gtctgtctaa
     3601 gcagtgaggt gtgaattgag tcaaatgctt aattctataa cattgagctg tgatggggag
     3661 cgaagtttag tagcgaagtt agtgacgtca cactgccaag aaaagcttct agcgtttaaa
     3721 catactttac ccgtaccgca aaccgacaca ggtagtcgag gcgagtagcc tcaggtgagc
     3781 gagagaactc tcgttaagga actcggcaaa atgaccccgt aacttcggga gaaggggtgc
     3841 tgactttaag tcagccgcag tgaataggcc caagcaactg tttatcaaaa acacagctct
     3901 ctgctaaatc gtaagatgat gtataggggg tgacgcctgc ccggtgctgg aaggttaaga
     3961 ggagtgctta gcgtaagcga aggtatgaat tgaagcccca gtaaacggcg gccgtaacta
     4021 taacggtcct aaggtagcga aattccttgt cgggtaagtt ccgacccgca cgaaaggcgt
     4081 aatgatttgg gcactgtctc aacgagagac tcggtgaaat tttagtacct gtgaagatgc
     4141 aggttacccg cgacaggacg gaaagacccc atggagcttt actgcagttt gatattgagt
     4201 gtctgtacca catgtacagg ataggtagga gtctaagaga tcgggacacc agtttcgaag
     4261 gagacgctgt tgggatacta cccttgtgtt atggccactc taacccagat aggtgatccc
     4321 tatcggagac agtgtctgac gggcagtttg actggggcgg tcgcctccta aaaggtaacg
     4381 gaggcgccca aaggttccct cagaatggtt ggaaatcatt cgcagagtgt aaaggtataa
     4441 gggagcttga ctgcgagagc tacaactcga gcagggacga aagtcgggct tagtgatccg
     4501 gtggttccgt atggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc
     4561 ttatctcccc caagagttca catcgacggg gaggtttggc acctcgatgt cggctcgtcg
     4621 catcctgggg ctgtagtcgg tcccaagggt tgggctgttc gcccattaaa gcggcacgcg
     4681 agctgggttc agaacgtcgt gagacagttc ggtccctatc cgtcgcgggc gtaggaaatt
     4741 tgagaggatc tgctcctagt acgagaggac cagagtggac ttaccgctgg tgtaccagtt
     4801 gtcttgccaa aggcatcgct gggtagctat gtagggaagg gataaacgct gaaagcatct
     4861 aagtgtgaaa cccacctcaa gatgagattt cccatgatta tatatcagta agagccctga
     4921 gggatgatca ggtagatagg ttagaagtgg aagtgtggcg acacatgtag cggactaata
     4981 ctaatagctc gaggacttat ccaaagtaac tgagaatatg aaagcgaacg gttttcttga
     5041 attgaataga tattcaattt tgagtaggta ttactcagag ttaagtgacg atagcctagg
     5101 agatacacct gtacccatgc cgaacacaga agttaagccc tagaacgccg gaagtagttg
     5161 ggggttgccc cctgtgaga
//
LOCUS       DAVDHZ010000074         4932 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000074 DAVDHZ010000000
VERSION     DAVDHZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.075"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            85..374
                     /locus_tag="VUR46_002099"
                     /pseudo
     CDS             85..374
                     /locus_tag="VUR46_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            397..930
                     /locus_tag="VUR46_002100"
     CDS             397..930
                     /locus_tag="VUR46_002100"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET5457446.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPVLYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTELLPAL
                     KTPHVIVMGNTSFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            1270..1524
                     /locus_tag="VUR46_002101"
     CDS             1270..1524
                     /locus_tag="VUR46_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457447.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            1635..2144
                     /locus_tag="VUR46_002102"
     CDS             1635..2144
                     /locus_tag="VUR46_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457448.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKPQNWQN"
     gene            2132..2741
                     /locus_tag="VUR46_002103"
                     /pseudo
     CDS             2132..2741
                     /locus_tag="VUR46_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818859.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            2699..3262
                     /locus_tag="VUR46_002104"
     CDS             2699..3262
                     /locus_tag="VUR46_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5457449.1"
                     /translation="MVPKTATSTETKIITRTIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVKSQEVTSDSSDKEITVRYDRL
                     STLEKPNPELPNQETPIPEPTPEPGTPKTETPVNPDPEVPTYETGKREELLNTGTEAN
                     ATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            3486..4355
                     /locus_tag="VUR46_002105"
     CDS             3486..4355
                     /locus_tag="VUR46_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET5457450.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQYMKQTAIQAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVVPIAA
                     AIAAVAVFKFLYL"
BASE COUNT         1688 a          873 c         1021 g         1350 t
ORIGIN      
        1 atttcagtaa aaaaaagtaa gtcttctaat aacaaaacat tgatatagtt gcttagtttt
       61 aaacaagcat attataataa agctatggca tatagtactg attttaaaca gcgagcatta
      121 gattacatca aagaggggca cagccatgtc gaggcagcca agttttttgg tgttggcgtc
      181 agaactctct tcacgtggga aaagaaagac gtaaacaagg acacatagag aggaaaaagc
      241 gagtcgtcaa aaaccgaaag attcctttag aggaattgaa agcctttgta gaggctcatc
      301 cagatgcttt tttacgggaa attgcggcac attttgattg tgctctgccc tccgtatggg
      361 cagctttaaa gtagattaag gtcactttaa aaaaagatga cgagctttaa ggaacaagag
      421 ccagagaaag tcgctgagtt tcttgatatt ttggataacc taaaagattt accagtccta
      481 tatattgatg aaacaggaat cgaccgctac ctctatcgtc cttatgcagg ggctcctaga
      541 ggggagaaag tctatgaaaa gattagcgga cgtcgttttg agcgaacttc aattgttgca
      601 ggacaagtag acggagagtt tatagctccc atgatttaca agaaaagcat gacaagcgat
      661 ttctttgtgg agtggttcaa aacagaactc ctgcctgctt tgaagacacc tcatgttatt
      721 gtcatgggca atactagttt tcatcccaag aacattttgg atgaactctg catccaagat
      781 aaacactttt tcttacctct accaccttat tcaccggatt tgaatcctat tgagcaagct
      841 tgggctatct tgaaaaagaa agtgacggat ttattaaggg aagttccaac tatttttgaa
      901 tgtttggaat gcttttttaa aactagatga ctataacggt tctaaaggaa cctatcgagt
      961 agtcattaaa actaaggata ctgctggtta agagaagacg gtatacgatc aaaccattca
     1021 ccgtgtagcc gaaatcgttc agaatgaaga cttgtataag gaaggtttga atgttgaact
     1081 tgcgcaccaa caaattaagg gattttttga agcagagttt aaaaatcgta ttaatggagt
     1141 tcttaatact aaaataaaaa atagtacatt aaatcgtgta aataaaaaaa ctatacacca
     1201 gagcaacaaa aactccatga tcaatttgaa gcagaagcaa cggaagatgc taaaaaacaa
     1261 ggcgatattg tgttgaatgt tgaccaggat ttcatgagca tatctaagtc taataaaagt
     1321 ggttcagact ggaagaaaac tttcacagtg aggacaacca ataggctagc aaatgacttg
     1381 aataatgtct tgaaacaggc tgataaagat actcctaata ccccaacttg gctaaactca
     1441 gctgcttcta aagctaaaga tgatgacaga gcatataaac tactgaagac tcttatacca
     1501 ggagaaaatt acctatcatg ttaaggataa tcagctagaa gtagaaacag ataaatacac
     1561 atatactgcc gctagaaatg gtagtaagga agttggtatt caagagtcag atatagcagc
     1621 aactctaagt gccgatgaat ataattctaa tcgccaaact tttgagagag aatacaaata
     1681 caaaagcaaa tgcccttaat aatggttggg ctagatctgg ttctgaagag ttcaaaaagt
     1741 tctcccactt tgtaggggta gacaaaggga ttgtgcgaac gaatgtactg actggtaaaa
     1801 aactatctga taagattagg aaagaagtgg gctctggaga tagcaaacta ggaaaaggcg
     1861 gctatttctc tactggggat gttctattag gaaaagatgt tgtttcttat accgtacaag
     1921 tattttcaga gaataatgaa agagtaggag taaacactca aagtcaccgt gttcagtata
     1981 atctcccaat tctagctgac ttttcagtca tccaagatac tgtggaacca tcacgaaccg
     2041 ttgttgaaaa aatcattcca aaactaaata ttcccgaaga agagaaaggg aaaataaccg
     2101 aagaaatcaa gaaaaagaaa aaacctcaga attggcagaa ctaatctcag aaaatgtgaa
     2161 agttcgctat gttgatgaac aagggcgttt gctatcattg aaaaatgata ctggaattgg
     2221 agaaaaagaa agtgacggaa cctacattac caataaaaaa acaactgatt ggtaccagct
     2281 ataatgtcac agataaaaaa ctcagtagca tgactactac tgacggaaaa tattatactt
     2341 ttaaagaagt agatacaaat tctgcaagtt taactgggaa tattgtaagc gaaggtagaa
     2401 cagtgacctt agtttataga gaaagcgaag cgccaaccac tgttacagta acagccaatt
     2461 actataaaga aggtagccaa gagaagttgg cagagtctgt tataaaagct gatttagcga
     2521 taggttctga gtataccaca gaatcaaaaa ctattgaagg gaaaacaaca actgaggata
     2581 aagaagaccg agttatcaca aggaaaacaa catacacctt ggtagcaact cctgcaaatg
     2641 cataccagaa gacggtgcaa cagttgacta ttactaccgt gagaatgttg aggaaacagt
     2701 ggttcccaaa acagcaacct ctactgagac gaagattata acgcgtacca ttcattacgt
     2761 tgataaagtt acgaaccaaa atgtaaaaga agatgttgtt caacctgtaa ccttaagccg
     2821 tacaaaaact gagaacaagg tcacaggagt tgtaacctac ggtgaatgga caacaggaaa
     2881 ctgggacgag gttgtatctg gtaagattga caagtacaaa gatccagata ttccaacagt
     2941 taaatcacaa gaagttacgt cagactctag tgataaagaa ataacggtaa ggtatgaccg
     3001 tttatcaaca ctagaaaaac caaacccaga actaccaaat caagagactc caataccaga
     3061 gccaactcca gaaccaggta ctccaaaaac tgaaactcca gtgaatccag acccagaagt
     3121 tccgacttat gagacaggta agagagagga attgctaaac acaggtacag aagctaatgc
     3181 taccttggct agtgctggta tcatgacctt gttagctggt ctaggattag gattcttcaa
     3241 gaaaaaagaa gatgaaaaat aatagatttt agaatctagg aacaaggaaa agctcacaga
     3301 tgtgggcttt tttcctggtt ttgagaacga ggtctttcgt gaagaataaa aacgcttata
     3361 aatctgttga actgggaaac tatgaatcct atttttttaa aaatatttcc agaaatcagt
     3421 tgctaaatag ggtaaaaatt gataaaatag ggaatatcta aaaaatttta aggagaatct
     3481 agcaaatgga tttcacatgg gcacttaagt atgccactga atttttggga actgccattt
     3541 tgatcattct tgggaatggt gcagttgcca acgttgaact taaaggtacg aaaggtcacc
     3601 aaagtggctg gatcgtcatc gctgttggtt atggtatggg ggttatgatc ccagccttga
     3661 tgtttggtaa cgtatctggg aaccacatca accctgcttt tactctaggg cttgcagtta
     3721 gcggtctttt cccttgggca caagtggtac cttacattat cgcgcaagtc ttgggggcta
     3781 tctttggtca agccttagtt gtggcaacat accgtccatt ctatttgaaa actgaaaacc
     3841 caaataacat cttgggaact ttctcaacta tttcaagtat tgaccatggt acaaaagaaa
     3901 gtcgctatgc agcaactgtc aatggtttga ttaatgagtt tgttggttca tttgttttgt
     3961 tctttgcagc tcttggtttg actaaaaact tctttggtgc tgaagtgctt caatacatga
     4021 aacaaacggc aatacaagca ggacaaacag ttgatttttc tgacttggct attaaagcac
     4081 aggtggctcc acacactgct tcaggacttt ctgtggctca cttggcactt ggattcctcg
     4141 ttatggcttt ggtaacatca cttggaggac ctacaggacc tgccttgaac ccagcccgtg
     4201 acttgggacc acgtctcctt catgctttcc ttccaaaatc agttcttggt gagcataaag
     4261 gcgattcaaa atggtggtat tcttgggtac cagtagtagt acctatcgca gcagcaattg
     4321 cggcagtagc tgtattcaaa ttcctttatc tctaagaaat agctccttta acatttgagt
     4381 gagcaccatc tataagtaag agaggatcag actggttctc tctttttgat tttttaggga
     4441 aatgaaagaa actctaaaca aactcctctc cagcagtggt ttagaagtct cagtgggcta
     4501 ttccagcttc aatgggctac tatagtgggt tgaagttgga atagtccccc cttctttctc
     4561 aaacattgtg aggaattgat ttaccttcct caacaaaatg ttcagtttct atttcatttt
     4621 gctataaaat aagcgattag gggggctatt cttcgaccta cattgactct gctgagtcct
     4681 atgattgtta tcgttttatc tgcaatttta tactcaatga aaatcaaagg gcaaactaag
     4741 aagctagccg caggttgttc aaaacacagt tttgaggttg tatagtagat tgaaactaga
     4801 ataatacaca tctacttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt
     4861 gccctattct tgtttcattt tactatataa accagagact gtttacattt tcagcaagtg
     4921 agtggatgga ta
//
LOCUS       DAVDHZ010000075         4718 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000075 DAVDHZ010000000
VERSION     DAVDHZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.076"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>4718
                     /locus_tag="VUR46_002106"
     CDS             <1..>4718
                     /locus_tag="VUR46_002106"
                     /inference="COORDINATES: protein motif:HMM:NF020018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457451.1"
                     /translation="GREFVNKNQPRDGRRYIDYNGRSHFNLSNLRVYWESSNIRGQQF
                     SDGTRPWPTNYLGKKREKLMVRYPGDNGRYDNRNDDYGARYEELDGTFIVKPVKPNIQ
                     TSLGKVGKNTLTVNNVNSGTTVVVYDAANPNNLKELGRTMVAKEGDYRIKNGVEVPLN
                     SGVTFKKDQKIVTKVIYKITDDDQRTESDVSDIWTVKESLIANGIHVIKGESYTGTAK
                     DRIRYNDNVDAEQRTGLPNNATASWAQNPNYTTLGTSNYTANVTVPGQGSATVNVPVH
                     VYAPANLKATSYNNKQGTLSNGANPENYIEFKDGNTVVTKPNNVTVRWQGGVAPRINT
                     PGHNRGVIEVVYPGNAGASSTVVKTFTVQLPTYHTTATATEYTRTIGENFAKTTARDY
                     ATTHNWNVGGSQYVWKNDETANREYSAENWGKVNGDWLGKKKNKVKVYYGNDNGSNSH
                     SENLAEETEEITFVTKPKTPSITATALNGKAGQRNQQVTVNNVTPGTTVELYNGDTKI
                     GSVDVSKANNEAYTDIKTVTVAVNGQLPLSSNIRAKTIYMPNNANEKVESDFSTSVQS
                     TTEGPQAPEISQNPENLLVKATVGQGGSTKVTLTYTDANGRVKEVGFTKNGQFWDKDD
                     ANADTTVSITNESNGTGEIQLQPGTAQEGTTVTVKQKTATSEFSTPATTKALGRLNGL
                     TNVAQADGSVDITVPDTATKFDLTYRNQQNNTTETLHYSKDAQGRWGNVTGITADGNR
                     FTLPKGLVTDGTTVSVIASNDNKTTKTVTSDAKFEMPDATTHTQRENGDGVITLPSTA
                     DSVTVTYTDAQDTAKTVTVTKNASNQWASTAALPEGVTLNGNELNVAYKNINSNGNVK
                     TVSTRGTGNVRSQEAVENIELNHIPVSTQAVVIAAGATPTNDDLGRGVTFAKRSITAK
                     STPAAVPAGTSAEIPATLTYNDGSTEDVTITVKSKPTAPSFNNLENHGTYSGLSSISK
                     VISGTAMPGAEKVKLTLQDGTVKEITPQADGSWSYTLGATEYLTQSFSGQFNGVFNQN
                     KVKAVQVKDGVESEETTANVAPGQATVDSVYKAGRAITVNIPHDIEAGYVRVNGTDYG
                     IQKVNGTWRVISTAPNAAKLEISNTVVDPTNKAVTKVTFSVKNNDDALYTPPFKIGNS
                     PVRFRTYYSKNGTINTPTPQIRGTDGWADSPTPKNTKPTVNFTADHTIEENKVFASPT
                     VEELKDYFEGHDAEDDASLTVGYSASNRGKLRVQVFTQDTNQSVRANTQGRIDPGNYR
                     LVLSTNDAADAESEPITRNITVKTYADVYRDKVLYPTNVDKVTYDDTAISNGNFTTAA
                     KTSFKDKIQELNGTVLPASTRYTVGTTDDKAKVAVINFPDGSTIDISHAVVAKPTVPT
                     VTRTHADKVSDADRTISGTALQSATKVTIYFQDGRGEQGHADVVPVNGQWTYTLPTGR
                     YLRQTEHTSLPGSSSVPVNVTQTVFDATSDKTAVYVAKDRNFTGKQIVGTKGSQELTA
                     LKNDAKKGINYTERNTPKDFPSDFDATWKETPDITTVGTRTYTAKVFEKDKGDAVSQE
                     ISVEVTVKADTPDAVAASYK"
BASE COUNT         1609 a          914 c         1029 g         1166 t
ORIGIN      
        1 ggtagggaat ttgtcaataa aaatcaacct agagatggta gacgctacat tgactataat
       61 ggaagatctc atttcaactt aagcaatcta cgtgtttact gggagagttc taatataaga
      121 ggtcagcaat tttctgatgg tacgcgacca tggcctacca attatttagg taagaaacgt
      181 gagaaattga tggttcgcta tccaggtgat aatggcaggt atgataatcg taatgatgac
      241 tacggtgcac gatatgaaga actagatgga actttcatcg ttaagccagt caaaccaaac
      301 attcaaacca gtcttggtaa ggtaggaaaa aatactctga ctgtcaataa tgtcaatagt
      361 ggaacaacag ttgtggtcta tgatgctgcc aatccaaaca atctcaagga attgggtcgt
      421 acaatggttg ctaaagaagg ggattacagg attaaaaacg gagttgaagt gccactaaac
      481 tctggtgtaa ctttcaaaaa agaccagaaa attgtcacca aggtcatcta taagattaca
      541 gatgatgacc aacgtacaga atctgatgtc agtgatatct ggacggtcaa ggaaagcttg
      601 atagcaaatg gcatccatgt catcaagggc gagagctata caggaactgc caaagaccgt
      661 atccgttaca acgataatgt agatgcggaa cagcgaacag gccttccaaa caatgccaca
      721 gcaagctggg cgcaaaatcc aaattatact actttgggaa caagcaacta cactgccaat
      781 gtaacagtgc cagggcaagg aagcgcgaca gttaacgtgc ctgtgcatgt ctatgcacca
      841 gctaacctga aggcaacttc ttacaataac aagcaaggta ccctatcaaa tggtgccaat
      901 ccagaaaact atattgaatt taaagatgga aatacagttg tcactaaacc aaataatgtg
      961 actgtgcgtt ggcaaggtgg tgtagcacct cgaatcaata caccaggtca caatagagga
     1021 gttattgagg ttgtctatcc aggaaatgct ggagcaagct ctacggttgt taagaccttt
     1081 acggttcaat taccaaccta ccatacaaca gctactgcta cagagtacac tcgtaccatt
     1141 ggcgaaaact ttgccaaaac aactgctcgc gactatgcga ctacgcataa ttggaatgta
     1201 ggtggcagtc agtacgtatg gaaaaatgat gaaaccgcta atcgtgaata cagtgcggaa
     1261 aactggggca aggtcaatgg cgattggctt ggtaagaaga aaaataaggt taaggtttac
     1321 tacggaaatg ataacggaag caactcgcat tctgaaaatc tagccgaaga gactgaagaa
     1381 atcacctttg tgactaagcc aaaaacacca agcatcactg cgacagctct taatggaaaa
     1441 gcgggtcaac gcaatcaaca agtgacagta aacaatgtca caccagggac aacagttgag
     1501 ctctacaacg gtgatacgaa aattggttct gtagatgtat caaaagctaa taacgaagct
     1561 tacactgaca ttaaaactgt tacagtagca gttaatggtc agttaccact ttcatctaat
     1621 attcgtgcaa aaacgattta tatgcctaat aatgcaaatg aaaaagtaga atctgatttt
     1681 agtactagtg tgcaaagtac aacagaaggt ccacaagcgc cggaaatttc tcaaaatcca
     1741 gaaaacttat tggtgaaagc gactgtagga caaggaggtt ctactaaggt tactcttact
     1801 tatacagatg ctaatggacg tgtgaaagag gttggattca cgaaaaatgg tcaattctgg
     1861 gataaggatg atgccaacgc tgatactact gtatcgatta ctaatgagtc taatggaaca
     1921 ggtgaaattc aacttcaacc aggtacggct caagagggaa caacagtaac agttaagcaa
     1981 aaaacagcta catcagaatt tagtactcca gccactacta aagctttagg acgcttaaat
     2041 ggcttgacga atgtagctca agcagatggt tcggtagata ttactgtacc agatacggct
     2101 acgaagtttg atttgaccta ccgcaaccag caaaataata caactgaaac acttcactat
     2161 agcaaagacg cccaaggacg ttggggaaat gtgacaggca ttactgctga cggcaatcgc
     2221 tttaccttgc caaaaggttt ggtgactgac gggacaaccg tttctgtcat cgcatcaaat
     2281 gacaataaga caactaagac ggttacgagc gatgctaagt ttgaaatgcc ggatgctaca
     2341 actcatactc agcgtgagaa tggtgacggt gttattacgc ttccaagtac tgctgactct
     2401 gtgacggtca cttatacgga cgctcaagat actgctaaga cggtcactgt gactaagaat
     2461 gctagcaatc aatgggcaag tactgctgcc ttgccagaag gtgtgacttt gaacggtaac
     2521 gagctcaatg ttgcttataa gaatatcaat agtaacggaa atgtgaaaac agtttcgaca
     2581 cgtggtactg gcaatgttcg ttctcaagag gctgtcgaaa atattgaatt gaaccatata
     2641 ccggtaagca ctcaagcggt tgttatcgct gctggtgcga caccgacaaa tgatgattta
     2701 ggacgtggtg tgacatttgc caaacgttct atcactgcta agtcaacacc ggcagctgtt
     2761 ccagcaggaa ccagtgcaga aattccagct accttgactt ataatgacgg ctctactgag
     2821 gatgtcacta ttactgttaa gtctaaacca acagcaccaa gcttcaataa tcttgaaaat
     2881 catggaacat atagcggatt atcctctatt tctaaggtga tttcaggtac agctatgcca
     2941 ggtgcagaaa aagttaaatt gactttacaa gacggtacag ttaaagagat aactcctcaa
     3001 gctgatggaa gttggtctta tactttagga gctactgaat acttgacgca aagcttcagc
     3061 ggtcagttta acggagtatt caatcaaaat aaggtaaaag ctgtccaagt gaaagacggt
     3121 gtagagtcag aggagactac agcaaacgtt gcaccaggtc aagcgactgt tgattctgtt
     3181 tataaggcag gacgtgcgat tacggtcaat atccctcatg atattgaagc tggttatgtt
     3241 cgtgtcaacg gaacagacta cggtattcaa aaagttaatg gtacttggag agtaatctca
     3301 acagcaccaa atgctgccaa attggagatt tcaaatacag ttgttgatcc aacgaataaa
     3361 gctgtcacta aagtgacctt tagtgttaag aataatgacg atgccttgta tactccacca
     3421 tttaaaattg ggaatagtcc tgtaagattc agaacgtatt attctaaaaa cggaaccatt
     3481 aacactccaa cacctcaaat tcgagggaca gatggatggg ctgattctcc tacacctaag
     3541 aacactaaac caactgtaaa cttcacagct gatcatacaa tagaagaaaa caaggtgttc
     3601 gcttctccaa ctgtagaaga gttgaaggat tattttgaag gtcatgatgc tgaagatgat
     3661 gcaagtttaa ctgtaggtta ctctgcttct aatagaggta aattacgtgt tcaagtattc
     3721 actcaagaca ctaatcaatc agtaagggct aatactcaag gacgtattga tccaggtaat
     3781 tacagacttg tcttgtctac gaatgacgcg gcagatgcag agtctgaacc gattacaaga
     3841 aatatcacag tgaaaactta tgctgatgtt tatcgtgata aggttcttta tccaacgaat
     3901 gttgataagg tgacttatga tgatacagcg attagtaatg gtaactttac aacagcagcc
     3961 aaaacaagct ttaaagataa aattcaagag ctaaatggca cggtgcttcc agcatcgaca
     4021 agatatacag taggaactac ggacgataag gcgaaagtcg ctgtgattaa cttcccggat
     4081 ggttctacta ttgatatttc gcatgcggtt gtagccaaac caacagtgcc aacggtaact
     4141 cgcacacatg ctgataaagt atcagatgct gacagaacaa tttctggtac agcccttcaa
     4201 agcgcgacaa aagtaactat ttatttccaa gatgggcgtg gtgaacaagg acatgcagat
     4261 gttgtgcctg taaatggtca atggacttac actcttccaa caggacgtta tctccgccaa
     4321 acagaacaca cttcattacc gggttcttcc tctgtacctg taaacgtaac acaaacggta
     4381 tttgatgcaa caagcgataa aacagctgtt tatgtggcga aagaccgtaa ctttacagga
     4441 aaacaaatcg ttggaactaa gggtagtcaa gaattgactg ctttgaaaaa tgatgctaaa
     4501 aaaggaatca actatactga aagaaatact ccaaaagact ttccaagtga ttttgatgct
     4561 acatggaaag aaacaccaga tattacaact gtaggaacaa gaacttacac ggctaaggtg
     4621 tttgaaaaag ataagggtga tgcagttagc caagaaattt cagttgaagt cactgtcaaa
     4681 gcagatactc cagatgcagt agcagcaagc tacaaaca
//
LOCUS       DAVDHZ010000076         4276 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000076 DAVDHZ010000000
VERSION     DAVDHZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.077"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            33..986
                     /locus_tag="VUR46_002107"
     CDS             33..986
                     /locus_tag="VUR46_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5457452.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLVFVFVFIGEFVAYTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNFGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            1063..3051
                     /gene="uvrB"
                     /locus_tag="VUR46_002108"
     CDS             1063..3051
                     /gene="uvrB"
                     /locus_tag="VUR46_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET5457453.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            3061..3624
                     /locus_tag="VUR46_002109"
     CDS             3061..3624
                     /locus_tag="VUR46_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457454.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            3590..4099
                     /locus_tag="VUR46_002110"
     CDS             3590..4099
                     /locus_tag="VUR46_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457455.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            4152..>4276
                     /locus_tag="VUR46_002111"
     CDS             4152..>4276
                     /locus_tag="VUR46_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutT"
                     /protein_id="HET5457456.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPDTNRWSGYAFPG"
BASE COUNT         1266 a          752 c          978 g         1280 t
ORIGIN      
        1 atagtatata tagaagaaaa gaggacgggg atatgaagaa caaaagaata tttaaagact
       61 tccaagcttc aaaaatgagt ttaaacattt acacaagccc cttgttagtc tttgtttttg
      121 tcttcatagg agagtttgtg gcttatactt tgtatggtat tggcttgtta gctctcatcg
      181 gacttgctag aaattttgga gaggctggtc aaaatcttgc aacctacttg cagaccttgc
      241 atcagagctt gacggataaa acaagtgact ttcgtttaat tttaggatta ctggcctttg
      301 gttttattct taacactgtg ttcagatgga caagaaaagt tgagaaaaga cctattcgaa
      361 ccttgggatt ttatagagag aatttcctca gcaatcttct gaaaggattt agtctaggtc
      421 tggcactttt tcttctgacc ttgttaggtt tagtggtctt aggtcaatat cgtttggaat
      481 ccattcactt gaatccttat tctcttgcct ttgtcgtctt tactatccca ttttggattt
      541 tacaggggac agcagaagaa gtggtggccc gtgcttggct acttcctcaa ttggcctcaa
      601 gaaccaatct aaaactagct attcttatat ctagcctgtt ctttaccctg cttcatatgg
      661 gcaattttgg cctcacccct ctatctctag taaatctctt tttattcgga gttgccatgg
      721 ctctttacct tctcaaaact gatacagttt ggggtgttgc aggtattcat ggtgcttgga
      781 attttgctca gggtaatctc tttggtattt tagttagtgg tcaaccgtca ggaacgtctc
      841 tgatgacctt tttaccacaa ggcaatcaag attggctatc aggtggttct tttggcatag
      901 aaggttccat tatgacaagt ctggtattac tactgctgat tgtctatctt gctaataaat
      961 taaagaaaga aaatgaaagg atgtgacttc ggtccgtcct tttcttcgtg aaaatactat
     1021 aagtatgcta aaataggaat agcacatgga gagaggattc ttatgatcaa tcacattaca
     1081 gataatcaat ttaaactagt atcaaaatat caaccatcag gagatcaacc ccaagctatc
     1141 gagcagttgg tggataacat tgagggggga gaaaaagctc agattctgat gggggcgact
     1201 ggaacaggga agacctatac tatgagtcag gtcatttcta aagtcaataa accaactctg
     1261 gttattgccc acaataaaac tctggctggt cagctctatg gggagtttaa ggaatttttc
     1321 cctgaaaatg cagttgagta tttcgtatcc tactatgatt attaccagcc agaggcctat
     1381 gtcccttcta gcgataccta tattgagaag gatagttctg tcaatgacga gattgacaag
     1441 cttcgccact cagctacctc agcccttttg gagcgtaatg atgttattgt cgtggcctca
     1501 gtctcttgta tctatggttt gggttcgccc aaggaatacg ctgatagtgt cgttagtctc
     1561 cgtcctggtc tagagatttc tcgtgataaa ctcttgaatg acttggtcga tattcagttt
     1621 gaacgtaatg atattgattt ccaacgcgga agatttcgcg ttcgtgggga tgtggtagag
     1681 attttcccag cttcccgaga tgaacatgcc tttcgagtag aattttttgg agacgaaatt
     1741 gaccgtatcc gtgaggttga ggctctgaca ggtcaggtat tgggagaggt ggatcatttg
     1801 gcgattttcc cagctactca ctttgtgacc aatgacgacc atatggaagt tgccgttgcc
     1861 aagattcaag cagaattaga agagcagtta gctgtctttg agaaggaagg taaattgctt
     1921 gaagcccagc gcttgaaaca acggacagag tacgatatcg aaatgctgcg cgagatgggc
     1981 tatacaaatg gggttgaaaa ttattctcgc cacatggatg gacgtagtga aggtgagcct
     2041 ccttatacgc ttctcgactt tttcccagat gattttttga ttatgattga cgagagtcat
     2101 atgactatgg gacaaataaa aggcatgtac aatggagacc gttcgcgtaa ggaaatgcta
     2161 gtaaattatg gtttccgttt accgtctgcc ttggacaatc gtcctctccg tcgtgaggag
     2221 tttgaaagcc atgtgcatca gattgtttac gtatcagcga cacctggtga ctatgaaaat
     2281 gaacagactg agacggtgat tgagcaaatc attcgaccga cagggctttt ggatcctgag
     2341 gtggaagtcc gtccgactat gggacagatt gatgacctct tgggtgaaat caatgcccgc
     2401 gttgaaaaaa atgagcgtac ctttatcaca actttgacca agaaaatggc agaggacttg
     2461 accgactact tcaaggaaat gggtatcaag gtcaagtaca tgcactcgga tatcaagacc
     2521 ttggaacgga cggagattat ccgtgacctg cgcttgggtg tctttgatgt cttggtcgga
     2581 attaacctgc tccgtgaagg aattgacgtt cctgaagtga gcctcgtagc tattctcgat
     2641 gctgacaagg aaggtttcct tcgcaacgaa cgtggactca tccagactat tggacgtgct
     2701 gctcgtaaca gtgaaggcca tgtcatcatg tatgcagaca cggttaccca gtctatgcaa
     2761 cgtgctatcg atgaaactgc ccgccgtcgg aaaattcaga tggcctataa tgaagagcat
     2821 ggtatcgtac cacagacaat caagaaagaa atccgtgacc tgattgccgt gaccaaggca
     2881 gttgctaagg aagaggacaa ggaagtcgac atcaatagcc tcaacaaaca agagcgcaaa
     2941 gaactcgtca agaaactaga aaaacaaatg caagaagccg tcgaagtgct tgactttgaa
     3001 ctggcggctc agatccgtga tatgatgttg gaagtcaagg ccttggatta ggggaatagt
     3061 atgatttatt taagaaagtt aaagagagaa gatttgatgt ctttatggga aatggcttat
     3121 tcacaactta atccagtttg gaaacagtat gatgctccct attatgatga ttatcagtat
     3181 ttttcaaatt ttaaagaatt cgaactacaa aaatcagaat ccattttaag caactcaaat
     3241 cgccttggta tttttgttga tgataaacta gttgggactg tttcgcgtta ttgggtatgt
     3301 aaacaaacaa gatggatgga attgggaatt ggtatttatg ataaaaaatt ctggaacact
     3361 ggtattggga aagttgctat gttgcagtgg atagatagga cgtttcagga ttacttggag
     3421 ttggagcatc tgggtttgac aacttggtca gggaatcttg gtatgatgaa acttgctgaa
     3481 aaattaagaa tgaaaaaaga agctcatatt ccaaaagttc gttattatca aggtaaatat
     3541 tttgatagta ttaaatatgg tattttgaga gaagactggg agaaaataaa tgacggttat
     3601 tatcaaatca atggaaactc ctaaagagat agaaggtaaa tcccttgttc actggcaaat
     3661 gtggagagag gcttatgatg accttttgcc tgcagaattt caggagacaa tgacattaga
     3721 aagatgtcga ctctttagtc aaaagtatcc agaaaataca ttgattgcga taggtgatct
     3781 gaaggtagtt ggttttatca gttatggtaa ctttcgtgat gagactatgc aagctggtga
     3841 aattattgct ttatatgttt taaaagacta ttacggaaaa ggcattgcac aaaagttaat
     3901 gaaagcagct ttgactgctc tgaatcattt ttctgaaatt ttcttatggg tattgaaaga
     3961 taacaagcga gccattgctt tctatcaaaa aatgggtttt acttttgatg gacaagaaaa
     4021 gatacttgaa cttggaaagc ctataaagga aaaacgaatg gtattctatt ctaaaataat
     4081 tttaaaaagt agaagctaat ggcactggta ccaagtctga aaatttaata aattagaaag
     4141 cgagtaaatt tatgtcccgt tcccaattaa cgattttaac caatatttgt ctgattgaag
     4201 acttagaaac tcagcgcgta gtcatgcagt atcgctctcc tgacaccaat cgctggtcag
     4261 gttatgcctt tcctgg
//
LOCUS       DAVDHZ010000077         4193 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000077 DAVDHZ010000000
VERSION     DAVDHZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.078"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..242
                     /locus_tag="VUR46_002112"
     CDS             <1..242
                     /locus_tag="VUR46_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HET5457457.1"
                     /translation="NSHLIYADYFEMKLKKLLKDDTKVFEKSTFKFVEGYKIYLTESK
                     ESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(600..1133)
                     /locus_tag="VUR46_002113"
     CDS             complement(600..1133)
                     /locus_tag="VUR46_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET5457458.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1222..1998)
                     /gene="recX"
                     /locus_tag="VUR46_002114"
     CDS             complement(1222..1998)
                     /gene="recX"
                     /locus_tag="VUR46_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET5457459.1"
                     /translation="MKITKLEKKKRLYLMELDEQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTHKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVNQETIQELILKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(2008..2784)
                     /locus_tag="VUR46_002115"
     CDS             complement(2008..2784)
                     /locus_tag="VUR46_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET5457460.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2841..4193
                     /gene="rlmD"
                     /locus_tag="VUR46_002116"
                     /pseudo
     CDS             2841..4193
                     /gene="rlmD"
                     /locus_tag="VUR46_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050284.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
BASE COUNT         1355 a          710 c          757 g         1371 t
ORIGIN      
        1 aaaattcaca tctaatatat gcagactact ttgaaatgaa attaaaaaaa ttattaaagg
       61 atgacacaaa agtttttgaa aaatctacat tcaaatttgt agaaggatat aaaatatacc
      121 tgacagaatc taaagaatct ggaattaaac aaatggacaa tgtcataaaa tattttgagt
      181 ttattgaatc taaaagtatt gctttatatt ttcaaaaacg attaaatgag ctgatagatt
      241 aaatagcatt ttctctgttg agatattgtt tttaaaatac tgtactaaat gattgatgct
      301 atgtggaaat acaaaaaaat gtttttgata cgaagttgac ctgtattttt tatactaatc
      361 attttcgtat tttttgtatt aaacgatata agtttgttgt aaacttacaa ggaataaaga
      421 cattaaaaaa taacagtata tctatttgtt ttatatattt tacgaattct gcataaatct
      481 ctttctagta atgtgttgta actctgctat aatggattta ttcctttttg tgtttacaca
      541 atttatttta tactaccaaa aaaacaaggt caggattttg ttcctgacct ttgacaactt
      601 taccgattct ttagttctac atagcgcttg taccaaatgt ttacataggc ttctgagaaa
      661 ggaccacgtc cattgttaat ccaatcaaca agaattttga catgttcttt taaaatatag
      721 tccaagtcat cagaataatt cattttgcgt ttgtgacgct cgtactcttc aacgtccaag
      781 agacgttttt ctccatctgt aaaaatttta acatccaaat cgtaatcaat atacttcagt
      841 gcttcttcat ccagatagta ggggctagcc atattgcaat agtaagaagt tccattatca
      901 cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa agtaaacaat agccggttct
      961 cgagtgaccc aacgacgacc atcactttcg gtaacaagtg tatgatcgtt gacaccgata
     1021 atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc aagttcggtg aagactccca
     1081 tcatgcttat aactttgaat tgtaataaag tcgccttctt ttggaagctt cataactaac
     1141 caactttcta caatttataa gtttatcatt tactattgta ccataaaatt acctaaaatc
     1201 tgtgaatttc acttggaaat attaaagata ttctctaaga gcgcttgcta tatccgaaaa
     1261 atcgtagccc tttcgtgcta aaacttgagt taaacgctgc ttcagttcgt atccttcata
     1321 ctttcgagca tacttactat attgtttatc aagttccttt aagatgagtt cttgaatcgt
     1381 ttcttggtta acttggctat ctaagtcgtc aaaggcaatt ttagcatcag aataagagaa
     1441 gcccttgtta gtcaagttct ggataatctt atcttgcagg gcacgagatg gaagttttcc
     1501 ctcatatttt ttcaatagtt tattagctac acgttgagca acttcagaaa aatcaaattc
     1561 tttcaagttc tcttctatag tagattttga aatccctttt tgagctagtt tatgagtcag
     1621 cacataagga cccttgtctc ctgaaagttg attggtattg atgatagcat aagcgtactg
     1681 accatcatta atccacttat cttctttaag attagcaata acttgagaaa cgatgttttt
     1741 atcaatatcg tattttttca gatattctct gacttctttt tcagtgcgtg ctttaaagga
     1801 taagtggtag agagcgagat tcttaccata agaaaactgg gcaaaatcct gaatctcggt
     1861 cagttcctct ttactaatga ccttatctcg agacagcata aaacggacaa tggtatcttc
     1921 cgtgatataa gaggtttgct gttcatctag ttccatcaag tagagacgtt ttttcttttc
     1981 aagttttgtg attttcataa tttcctttca tctaaatgct tcgaaagctg caacaagtcg
     2041 tagtttatcc atatttacat attctctacc gtaatagtcg agaaataatt cagcatacgt
     2101 agcatcttgt aggttgtaat gaagggacca aattgcccaa aagaggtcga tatgtcggtc
     2161 actaaaacca gccaatccca agtcaataaa gcaagaaaaa tgagaggcat ccttcaagat
     2221 gaaatttggc aggcaggcat ctccatgaat aaaagcatca gctttgagaa tgtaaccttt
     2281 ctcttgtatc agttggtaag cttcttcacg actgtgaatg tgaaattgag gcagaagagt
     2341 cttgttataa aaagtcccct tctgatagtt ttttaaggct ttttctttat aacgcttcag
     2401 atgattttcc gacggaaaag attgtggttt aagactgtga agtttgttta atgcttgagc
     2461 cagggtttga cagagtcttt cgggttgatt taaaaaagcg agagcgttgc tgccaatggc
     2521 ttctttagtc agaaggaagt ccttatttgc tgataaatag gtaatcactg gagttcccaa
     2581 tccttcagtt tcgaaccaac ttgcaatctt agcttcttga gctaatctgc ctttttgatc
     2641 tatttttaaa tagtaacctg aatctatata taggacagtt gcacttgaat gagaagaact
     2701 atcagagaga ttagctccct tgatatagct tcgtaattgt tcagggaaat ctagtatact
     2761 aaagcgaggt gtttttgaat tcatgctttt attgtaacat attcttaaat atcttagaaa
     2821 ctccatggta taatagacat atgaatctga aagtgaaaca aaaaatacca ttaaaaatca
     2881 aacgcatggg aattaatggt gagggaatcg gcttttacca aaaacattag tctttgtacc
     2941 tggagctctc aaaggcgaag atatctattg tcagattact tctattagac gcaactttgt
     3001 tgaagcaaaa ttactgaagg tcaacaagaa gtctaaattt cgaattgtgc catcttgtac
     3061 tatttataat gaatgcggag gctgccaaat catgcacctg cattatgata agcagctgga
     3121 gttcaagacg gacttacttc atcaagcgct gaaaaaattt gctcctgcag gatatgaaaa
     3181 ttatgaaatt cgtccaacta ttggaatgca ggaaccaaaa tattacagag ctaagttaca
     3241 atttcagact cgaaaattta aaaatcaggt caaggcgggc ttatatgcac aaaactctca
     3301 ctatttagta gagttgaaag actgcctggt acaagataag gaaacccaag tgattgctaa
     3361 tcgcttagca gaattactta cttatcacca gattccaatc acggatgaga gaaaagttct
     3421 aggtgtccgt actattatgg tccgacgcgc gagaaagacc ggacaggttc agattattat
     3481 tgttacaaac cgccagctta atttaaccca actggtaaaa gagttggtta aagattttcc
     3541 agaagttgtg acagtagctg ttaatacaaa tacagctaaa accagtgaga tatatggtga
     3601 aaagacagag attatctggg ggcaagagag tattcaagaa ggtgtactca attatgaatt
     3661 ttcactatcc cctcgagctt tttatcaact aaatcctgag caaacagaag tcctctatag
     3721 cgaagcagta aaagcgctgg atgttgataa agaagaccat ttgattgacg cttattgtgg
     3781 agttggaacg attggatttg cctttgcaaa gaaagtaaaa acactcagag gtatggatat
     3841 tattccagaa gctattgaag atgccaagcg aaatgctaaa agaatgggat ttgacaatac
     3901 tcattatgaa gctggaacgg cagaagagat tattcctcgt tggtacaagg aaggctaccg
     3961 agcagatgct ttgattgttg acccaccacg tacaggtctg gatgataagt tattagatac
     4021 tattcttact tatgtaccag aaaaaatggt ttatatttct tgtaatgttt cgaccttggc
     4081 tcgtgatttg gtacgcttag tagaagtcta tgatcttcat tatatccagt cggtcgatat
     4141 gttcccacat acagctcgaa ctgaagctgt tgtaaaatta ataaaaaaag ttt
//
LOCUS       DAVDHZ010000078         3970 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000078 DAVDHZ010000000
VERSION     DAVDHZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.079"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..127
                     /locus_tag="VUR46_002117"
     CDS             <1..127
                     /locus_tag="VUR46_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET5457461.1"
                     /translation="FRSLENLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(255..458)
                     /locus_tag="VUR46_002118"
     CDS             complement(255..458)
                     /locus_tag="VUR46_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5457462.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(451..1533)
                     /locus_tag="VUR46_002119"
     CDS             complement(451..1533)
                     /locus_tag="VUR46_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET5457463.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVPADQEPILFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLNKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1659..2441)
                     /locus_tag="VUR46_002120"
     CDS             complement(1659..2441)
                     /locus_tag="VUR46_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET5457464.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVIVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2441..3784)
                     /locus_tag="VUR46_002121"
     CDS             complement(2441..3784)
                     /locus_tag="VUR46_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET5457465.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGVDSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
BASE COUNT         1135 a          788 c          893 g         1154 t
ORIGIN      
        1 ctttagatct ttagaaaacc ttgaacaagc tattgtggac tacattgatt actacaacaa
       61 caaacgaatt aaggtaaaac taaaaggact tagtcctgtg cagtacagaa ctaaatcctt
      121 cggataaatt aattgtctaa ctttttgggg ggcagttcat tctacaccca ctattatgcg
      181 ttttattgtg ggaagatttt cctcattttc tagtgaaatt gaactttttc taacatcttt
      241 tgatagatga cttcttaatc aattatcatt tccattgttg tttcttgggg tttcatccct
      301 tgtctttgat aaaagcggag agcaccctcg ttatcattcc agacacttag ggttagatta
      361 ttgcagccaa tttctttagc ataatagcag aaaaatgaca ataaaatagc ccctagatat
      421 tttgaaagga aagcataggg gctatatagt ttaatcaaaa taaagcaaat ctttgctggt
      481 gcttgtaaag aggtcgaagc catccttggt aacaacaccg cagtcttcaa tacgaacacc
      541 gactttacca gggatataga tacctggttc aacagagaag cacatgcctt cttcgatgac
      601 catgtcgttt ccttccatga tagatgggaa ttcatggaca tccataccga taccatgccc
      661 gagacggtgg ttgaagtact caccataacc agctttttcg atgacctcac gggcagcgcg
      721 gtccacttca tgagcagtca cacctggctt gataaagtca agagcagctt gttgggcttc
      781 aagagtcaag ttgtaaatat ctttcttgaa ttggtctggt ttgccgacag cgactgtacg
      841 agtcatatct gacgcatagc cattgaccag aacacccagg tcaaagagga gaagagcatc
      901 attttcaacc ttattagctg ctggaatgcc gtgtggattc gcagcattat caccagtcaa
      961 gaccatggta tcaaagctca tttcataacc ttcacgtttc atggcaaagt cgatttgtgc
     1021 gatgatatct gtctcagtct tattaagaga aatattgtca aaaccaacat gaacagcctt
     1081 gtcagcataa agacctgcaa ccatcatttt ttgcacttca tcagctgatt tgatgaggcg
     1141 catgcgttgg atacgaggag tgaggttgtc aaactcagca gtctcaaaaa ctgttttcaa
     1201 accatggtat ttggtcaaga tgagattgtc aaactcaaca gcgacacgtt tgaagtcaag
     1261 ttgtggaaga gcatgtttga ttttttgcca tggattttca gaatcgacat agcccactac
     1321 tgggaaggaa acggtgctac ttgcacgttc tacttcaaga gctgggacaa agaggatagg
     1381 ttcctgatcc gctgggacaa agaggaacat ttggcgttca tggggatcac tgtaaaaacc
     1441 agtgaggtaa ttgattgtga cggggtcaga tacgacagcg acgtctagtt tttctgattc
     1501 aagatatgtt aggatttgtt gtaatttaga catatgctac cttctttcta cccctctatt
     1561 ttggcaaaaa atgagagaaa atgcaaggga gaagggtaaa agaaaagaca aaaaactccg
     1621 acaagataac ggagttcttt gatatcattt tcctttgttt aagaaaagtc agccttgctt
     1681 ttgacgtcac tgtactcttc agcgatttct tggctgagaa tatcctcata ggcagggagt
     1741 tggatgtcct gaccatattt cttcttgagg gcagtagtaa ctaggcgata agccagattg
     1801 gcattacgag agaggatagg cccgtggaag taggaaccaa agacattctt ataatgaacc
     1861 ccttcaccga ccttttcttc gttgtttcca tttccataga caacctgtcc cagcggtttt
     1921 tggtcatcag agaggaaggt acgaccttgg tgattttcaa atccatagta ggtttcatcg
     1981 aaatcttcat tgtgaatctt gatgtcaccg ataaaacggt tattggtctg gttgagcgtg
     2041 tagtgtccca tgacccctag cccttcgata cgttttcctg aagcttcaac ataatattga
     2101 cccaatagtt ggaaaccacc gcagatagcc agaactacac cgtcgttttg gatgtagttg
     2161 tcaatgctct cttttttagc aggtaggtcg tctgcaatga tactttgttc aaagtcttga
     2221 ccaccaccga aaaaggcgat gtcgtagtga ttttcatcaa agtcatcatg gagagaaacg
     2281 atgtcaacga tcacatgggc tcccagtttt tcagccacat acttgagcat gaggatgttt
     2341 ccattgtccc cgtaggtatt catgagattt ccgtagaggt gggcaatgtt gagctgatag
     2401 gggtaattgc catcttttga ggaaagtgaa gtataaacca ttagttcatc tcctttctaa
     2461 caatctgacg actagccagc agttcacgaa attccagcat ggcagtataa gttgccagaa
     2521 tataggcatg cttgcagtct tgattctcaa tggtcttgag aacttgctcc agattactcg
     2581 tttcagtgat tttctcagct ggatagccag tcactcggag gcgacgagcg atttcagaat
     2641 gacgaacacc gccagcgttg atttcaggaa tgtccatgtc agtgatttgt tcaaagtctg
     2701 catcccagat ccagctagtg tcaattccat ctgcatagtt ggcattaagg aggacagata
     2761 ggctaaatgg ataaggtgct agtttgatca tttcgatagc ttgggttgca ccgactggat
     2821 ttttaatcaa gacaagggta cattccttgt caccgatatg aaaggtttct tggcgtccaa
     2881 agacagcacg gctcttgtca aatccctgtt tgatgagttg cgaatcgaca cctaggaaac
     2941 gggcgatggc cacagcagct agggcgttat agatattata gagcccgccg atttggatac
     3001 cgtattcttg gccgtctatg acaaagcgag agcgattgtt ggtcaactca accagttttg
     3061 tcaaacgata gtcgagatca ggacgtttac atccacaacc ttcacagata taggcaccca
     3121 agtttgcata ggtattatgc tcatatttga ggatgccttg gcagtcagga cagagaatcc
     3181 cttcggtatt gtagtgagcc agttgggctg gtcctttttc caagtcaaaa ccaaaatact
     3241 ctatagggtt tggaatagtt ggcttgtaga aaagtggact gtctccgtta aggagaacag
     3301 tagcagttgg aactttccga atggcatcca atatcatgtt ataggtagta tagatttcac
     3361 cgaaacggtc catctggtca cggaagatat tagtaatgac aaaaagacta ggctggatat
     3421 agtcacagat acgagataga ctggcttcgt cgatttctag gacggcaata tttttcccag
     3481 ttttagaaga tttggctgtt aagaaggttg tcgcaattcc tgtaatcatg ttggcaccgc
     3541 ttgggttggt cagaacttga ccataaactt cttttaaaat accgacagtg agggcagttg
     3601 tcagggtttt tccatttgtt ccagtgacaa cgacaatctc gtagttctta gctaggcttt
     3661 gtaaaatatc tttatcaaat tgaagggcga ctttccctgg gagcgtactt ccacgtccaa
     3721 gacggcttaa aacgaagtgg gaagaacgcc cagcaagaag gcccaaagta gtttttaagt
     3781 tcatgtttct attatatcac aaaagaggga aaagacagat ttggtgtttc gtagaagtaa
     3841 aaacagccca aagagggctg tcagttaaga tgagatttca acttaaatcg caaacaagtc
     3901 attcaagttc tcagccaagg ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg
     3961 aatcttgttg
//
LOCUS       DAVDHZ010000079         2954 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000079 DAVDHZ010000000
VERSION     DAVDHZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.080"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(56..328)
                     /locus_tag="VUR46_002122"
     CDS             complement(56..328)
                     /locus_tag="VUR46_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457466.1"
                     /translation="MFTTFFKKNQDNSDVFKKLIHRLSDMSVQDPEKIDRLLDIIFTP
                     DQGSEQLKTEATYREEILDDTLKEAKNQLHKEQLEKNLERFRKNSQ"
     gene            complement(366..749)
                     /locus_tag="VUR46_002123"
     CDS             complement(366..749)
                     /locus_tag="VUR46_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET5457467.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            complement(746..979)
                     /locus_tag="VUR46_002124"
     CDS             complement(746..979)
                     /locus_tag="VUR46_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457468.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGRERQFDESEFRKDEMSE"
     gene            complement(1030..2115)
                     /locus_tag="VUR46_002125"
                     /pseudo
     CDS             complement(1030..2115)
                     /locus_tag="VUR46_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            complement(2125..2766)
                     /locus_tag="VUR46_002126"
     CDS             complement(2125..2766)
                     /locus_tag="VUR46_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET5457469.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGELLVNQVQVWKSGLDDLDKATPKTLEESSSISSLPNTTTK"
BASE COUNT          860 a          565 c          448 g         1081 t
ORIGIN      
        1 atttgatacc accattataa catttagaaa aagcaaatgc accatttttg gtgcgttatt
       61 gactgttttt cctaaatctc tctaaattct tctccaattg ttccttatga agttgattct
      121 tagcttcttt taatgtgtcg tccaaaattt cttctctgta agttgcttct gtttttagtt
      181 gttctgatcc ttgatctgga gtgaaaatga tatctaacag tcggtctatt ttttcaggat
      241 cttggacaga catatcagat agtctatgaa ttagcttctt aaatacatca ctattgtctt
      301 ggtttttctt aaaaaatgtt gtaaacatct ataacctctc aaaaaaagca gcctatcagg
      361 actgcttagt gtaattccga aatcgcatca taaatggact gcaatttctt attgtcttta
      421 ttctttgtgt caatcaacgt atgtagctct tcaattttct tttgactact ttgaatatca
      481 ctattgttat ccgcaatcag tcttttaaga tgttgctgat aacttgtagt gatatctgtc
      541 tcttttcctg ttctaacctc tgtaactttg ggtttagaac tagaatttga ttccgtcaca
      601 ggtgcttgtt tgcgcttttg aaaagccgct tcataattta catcattacc tccttgatga
      661 tttccaaata aggccgcaat tttatctgga tcttcttgat tttctgattt actttctaat
      721 ggttgattaa aattccaatc ttttgtcatt cactcatttc atcctttcta aattcagatt
      781 catcgaattg tctttctcta ccgaaggcat ggtcaagagc ttcttcaaaa ctcatgtgac
      841 taatgctttg acgccttttg aacgtcgcaa acatcgctgt ctccagttgt tctttgtaag
      901 cagcgagttt ttctgtctct cttgctacct tactttcttg cctagtgacc ttttcttcta
      961 agcgttcaat aatggtcata tacgatcctc cttcattcta atattagcta aaacatcttg
     1021 attttgttat cacaattcta aacattgaga ggtttttctt actggttgat tcctcaatgt
     1081 ctcttttgca ttctcgatca tcaattgtaa atctgatttc ttttctctaa ggacatcatt
     1141 ccagtctact ttttctttcc cagatttatt atcagggaaa tccaggaaaa caggaaatcc
     1201 tgattgagat aacttatcag aaaaatcttt tcctgcatca tcacaatcta ccgcaagtgt
     1261 caataaatca ggatgattat caaaatagct ggtggtatca cgaattgtat tgattaaagg
     1321 caataacttt gaaggtatta ctgtatccaa aaattccaac ttctgatttt cttcagctat
     1381 cagtcgtaaa atttgataag caacaacaga cctttttaat ccttccatag ataccaaacg
     1441 aacatcagat agactttgtt gatgaagttc gtaatagctc attaagtcga tgaacgattc
     1501 acaaaagacc agtctattag gtttaccaat atcaaaggat attccaacat gtccatggct
     1561 tccttttaga atcgttttta acctctctct aggaagagag tgattcttat aaatccctta
     1621 gagacttgct gcctgcagct tgtaacgatg atcaaagctt ttaaaaacaa taacaggttc
     1681 aacagtttca tttgttttcc agctagcttg tgctatcaaa ccttgttgaa tcatcttttg
     1741 aacgatttct tctgaaattc ctctacattc tgttaaataa tatctagcca gactgcagtt
     1801 agaatcttct actctcttta aaggataata aaatggtctc tctctttttt cttgaacagc
     1861 ttctttttga aaaggttctt cagaaagaaa ggctagagct tctttaaagg aaattccctt
     1921 aacaagtcga acaaaatcaa tgacatcacc ttgaatatct cttgaaaacc atttaaaagt
     1981 attggtagtt gaaaaaatcc gaaatgaatc gtgttcagga tgttcataga cacggctaga
     2041 aacttgttta aaggagatac ctaaacgatt ggctacatca agaattgaaa tttgcttaca
     2101 ttcttctatt tccatgcaat atcatcattt tgtcgtagta tttggcagtg atgatattga
     2161 tgatgattct tctaaagttt taggagtggc cttatccaaa tcatctaacc cagatttcca
     2221 aacctgtact tgattgacca ataactcacc tggtagtttc gaataagaca acttaaccgt
     2281 tctggtttct gtctgattgg tctttgattg gttggcattc tttaaatcag atacataggt
     2341 tacattataa gagaccatgg caatggcttg attcgtagtc tgattgacaa agatatcagc
     2401 tttttcaaaa tgataatcta aaatataatc cttatacact tggttcatgg catcattttg
     2461 acttgacaat tcttgagaat aagccgattc agtcatataa ggttgaatac gtgtattatt
     2521 ttctccgagc ttttctttcg tatagtactg cgtcaaaaat tcttttacag tatccgatga
     2581 caaaatgctg gctttatctt ctgcttgttt atcctctaca agtttagctg cagccaattc
     2641 aatctcttta cgactttgtt tagcagtcga gtgttgacca gcagtatatc ccatcatgag
     2701 aataaagcta gttgcagcca ctgctccaac actaattaag gctttagttt tgactttatt
     2761 taacatctta gaccttcttt ctataaaaac taggtcaaga atagcagata aatcttgaaa
     2821 aaagtatcac agaagtaaaa atgccacccg aaggtggcca atataactta caaaattagt
     2881 aatccgtctg ataaagtttt ttatacaaac catttttcat attcaatagt tctgtatgac
     2941 ttccttgttc taca
//
LOCUS       DAVDHZ010000080         2745 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000080 DAVDHZ010000000
VERSION     DAVDHZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.081"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            706..2628
                     /gene="ltrA"
                     /locus_tag="VUR46_002127"
     CDS             706..2628
                     /gene="ltrA"
                     /locus_tag="VUR46_002127"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET5457470.1"
                     /translation="MTKPKNDDKLLKHQKLRYAEYYGMTEIFDDLYSKSQNGFSFKNL
                     MNIITSPENILLAYRTIKRNGGSQTEGVDGVTIKDLENLTQEDFISKVQRRFQYYRPR
                     KVRRVEIPKPNGKKRPLGIPSMWDRVAQQCILQVLEPICEAKFYKHSYGFRPLRSADN
                     AIMDCMYRMNKSHMTYVVDVDIKGFFNEVNHTKLMRQIWTLGIRDKQLLVIIRKMLKA
                     PIVLPNGKVTYPTKGTPQGGILSPLLANINLNEFDWWIGRQWEERDCKELVPQYNSKG
                     TRHKSHVYRKLRTSTTLKEVYIVRYADDFKIFCRNRNEAERTFKAVKLWLKERLNLPI
                     SEEKSQITNLRKKSSEFLGITLKLVSKNNRLVCFSHIASKAKKRIKHQLKQQMKLIQI
                     KGAKETIIREIQKYNSMVIGIHNYYSMATHVSKDLEEIHYQLYLSFKNRLQAKGLTKI
                     GEYKGKDKGLLPYLQSQNIRYLMGYPILPISYVKTRTLKGRNKNLNRYTPEGRKLIHK
                     QQESVETWKLKWLREHSIINKRATVEYNDNRISLFVAQKGKCAVTGQELDMDDIHCHH
                     KRPWLETKDDSYRNLIIVGRDIHRLIHATNEKVIKNLFQLLNLSDTGLTKLNQLRELA
                     GNSPLLKENLNLEQLC"
BASE COUNT         1004 a          425 c          577 g          739 t
ORIGIN      
        1 aaaaggttag acacgttctt gaaaaatcaa cctgataatc aggttaaatt tgaatagaat
       61 ggagaactct tatcttgaaa attggaatga aggggtaacg ccctgaaacg atttctctaa
      121 tactccgaca tgcgtttatc ttgtgcaaag gtaaaggttt gaagctcggt gaagtcggct
      181 gaaagatacc gtcattctta aggacttaag aatcgaaagt gttccagagg tggaatatgt
      241 atctgatagg tcgggagtca ttaaaaacta aatagggtga gaatgtgcat gagcactgac
      301 gaaccagcga atgtacgctc cgaaggcgag tacgtagaaa tgcgtataac aacgtaagtt
      361 gtttcaactt gaggaagagt aagaatcgac gatatgaaat tccttgttat gttacaggca
      421 tatcaaagtt gaaggggtat agctaggcac ctaagtttag tattgataaa gataagggaa
      481 cgtcgaaagc tagagatgtg gaggttgcac aaccagagaa acattggaaa gaaaatcata
      541 actttcctta atctctagtg agagtggtgg cacgaccttt gaaagtgttg taatgatact
      601 ggaggaacag ccactagtca atagtgtatt gttatgaact ttatcatttc atggattctt
      661 gtaagacata aaaggtcacg aatccaaaga gaggagtgat agaccatgac gaaaccaaaa
      721 aatgatgaca aactattaaa acatcaaaaa ctaaggtatg cggaatacta tggcatgacc
      781 gagatatttg atgatttata ttccaaaagt caaaatggat tcagttttaa gaacttaatg
      841 aacattatca catctcccga gaatatactg ctcgcttatc gtaccataaa gcgaaatggt
      901 ggtagtcaaa ccgaaggagt agatggtgtt accattaaag atttagaaaa tctgacccaa
      961 gaagacttta tctctaaagt tcaaagaaga tttcaatatt atagacccag aaaagtcaga
     1021 agagtagaga ttcctaagcc aaatgggaag aaacgaccac ttggcattcc ctcgatgtgg
     1081 gacagagtag ctcaacagtg tattttacaa gtgttggagc caatctgtga agcgaaattt
     1141 tacaaacaca gttatggatt tagaccctta aggtcggctg ataacgctat tatggactgt
     1201 atgtatcgta tgaataaaag tcatatgact tatgtcgttg acgttgatat taaaggcttt
     1261 tttaatgaag tgaatcatac taagttaatg cgtcaaatct ggacattagg tatcagggac
     1321 aaacaacttc tagtgattat tcgaaaaatg ttaaaagcac caattgttct tccgaatgga
     1381 aaagtgacat atccaactaa gggcacacca caaggaggta tcttatctcc actacttgcc
     1441 aatatcaatc tcaatgaatt tgattggtgg ataggacgac aatgggaaga aagagattgt
     1501 aaggaattag ttcctcaata taattccaag ggaacaagac acaagtcaca tgtttacaga
     1561 aagctgcgaa cttcaacgac gctaaaagaa gtttatattg tccgatatgc ggatgatttt
     1621 aaaatctttt gtcgaaatag gaatgaggca gagcgaacgt ttaaggctgt aaaattgtgg
     1681 ttaaaagaac gacttaacct ccctatttca gaggaaaaat ctcaaattac caatctgaga
     1741 aagaaaagca gtgaattcct tgggattact ttaaagctag tttctaagaa taatcgtttg
     1801 gtttgtttct ctcatattgc atcaaaagcc aagaaacgta ttaaacatca actgaaacaa
     1861 cagatgaaat tgatacaaat taaaggtgct aaagaaacaa ttattcgtga aatacagaag
     1921 tataatagta tggttatcgg tattcataac tattatagta tggcaacaca tgtgagtaag
     1981 gatttagaag aaattcatta tcagctttat ctctctttta aaaatagatt gcaggcgaaa
     2041 ggtctgacaa aaataggaga atacaaggga aaagataaag gacttctccc ctacctccaa
     2101 tctcaaaata ttcggtactt aatgggttat ccaattcttc caattagcta tgtcaagacg
     2161 agaacactaa aaggaagaaa taagaatctg aataggtata ctcccgaggg gagaaaattg
     2221 attcataaac aacaggaatc tgttgaaaca tggaaattaa aatggctgag agaacactca
     2281 attataaata agcgtgcaac agttgaatac aatgataatc gaatttcttt atttgtagct
     2341 caaaaaggga aatgtgctgt aaccggtcag gaattggata tggatgatat tcattgtcac
     2401 cataagagac cgtggttaga aacaaaggat gactcttata ggaaccttat cattgttgga
     2461 cgagatattc atcgcctgat tcacgcaaca aatgagaagg ttatcaaaaa tctctttcag
     2521 cttttgaatt tgagtgatac aggactgacc aaattaaatc agttgcgcga acttgcagga
     2581 aattcaccat tattgaaaga aaatttgaac ttagaacaat tatgttaatc atattaatac
     2641 agcacgataa agcaaaatcg tgataataca ctattgatgg aacgccgtgt gcggtgaaag
     2701 tcgcacgcac ggtgtgaagc gggggaaaag atggagatag tatca
//
LOCUS       DAVDHZ010000081         2742 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000081 DAVDHZ010000000
VERSION     DAVDHZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.082"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            4..1008
                     /locus_tag="VUR46_002128"
     CDS             4..1008
                     /locus_tag="VUR46_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5457471.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKNEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKVYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLVSVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            1077..1943
                     /locus_tag="VUR46_002129"
     CDS             1077..1943
                     /locus_tag="VUR46_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5457472.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGIKQIQDVLPFDSDLNRLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            1940..2698
                     /locus_tag="VUR46_002130"
     CDS             1940..2698
                     /locus_tag="VUR46_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5457473.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSSEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGQIIQDLNQEEKAKMKISDYYQLFE"
BASE COUNT          849 a          480 c          607 g          806 t
ORIGIN      
        1 agaatgaaaa ataaacgttt aattggaatt atcgctgcat tagcagtctt agtagcagga
       61 agcttgattt attcttcaat gaataaatca gaagctcaga ataataagaa tgagaagaaa
      121 ataaccaaga ttggtgtgct tcaatttgtg agccatccat cccttgattt gatttataaa
      181 gggatccaag atggacttgc agaagaagga tataaagatg atcaagttaa aattgatttt
      241 atgaactcag aaggtgatca aagtaaggtt gcgacaatga gtaaacaatt ggttgcaaat
      301 gggaatgacc ttgtggttgg tatcgcaaca ccagcagccc aagggttggc tagtgcaaca
      361 aaagacctac cggttatcat ggccgctatt acagacccaa ttggtgctaa cttggttaaa
      421 gatttgaaaa aaccaggtgg caacgttaca ggggtatctg accacaatcc agctcaacaa
      481 caagttgaac tcatcaaggc tctgacaccg aatgtgaaaa caatcggagc tctttactca
      541 agtagcgaag acaattcaaa aacacaggtc gaagaattta aggtttatgc tgaaaaagca
      601 ggtctgacag tggaaacatt tgcagttcct tcaacaaatg aaattgcctc aactgtcact
      661 gttatgacta gcaaggtaga tgctatttgg gttccaattg ataacaccat tgcatcagga
      721 tttccaacgg ttgtctctag caatcaaagt tctaagaaac caatttatcc cagtgcgaca
      781 gctatggtag aagtaggtgg tttggtatca gttgtaattg accaacatga ccttggtgta
      841 gcaacaggta aaatgattgt gcaagtcttg aaaggtgcaa aaccagccga taccccagtc
      901 aatgtctttt caactggtaa gtcagtcatc aataaaaaaa tagcacaaga actaggtatt
      961 actattcctg agtctgttct caaagaagca ggacaagtca tcgaataaat aaggtaggga
     1021 ggaggagact ctttccattt tttaaaaaga tgaatataga aaggattaaa taaaatatga
     1081 ttgtttccat tatttctcaa ggatttgtct gggctattct aggtctggga atctttatga
     1141 catttaggat tttaaacttt ccagatatga cgacagaagg ttccttccct cttgggggag
     1201 ctgttgctgt cactttgata accaaaggcg tgaacccatt tttagcgaca cttgttgctg
     1261 taggagcagg ttgtttggct ggaatggcag caggccttct ttatacaaaa gggaagatcc
     1321 caaccttgct ctcagggatt ttggtgatga cttcttgtca ctcaatcatg ctcttgatta
     1381 tgggacgtgc gaatttaggc ctgcttggaa tcaagcaaat tcaggatgtt ttgccttttg
     1441 attcggattt gaatcgactc ttgacaggtc tcatctttgt gagtattgtt attgctctca
     1501 tgctcttttt cttggacact aaactcggac aagcctatat tgctacaggg gataatcctg
     1561 atatggctag aagtttcggg attcatactg gacgcatgga gctcatgggc ttggtcttat
     1621 caaatggtgt gattgccctt gcaggtgccc tcattgctca gcaagaaggc tatgccgatg
     1681 tgtctcgagg gatcggggtt atcgttgtgg ggcttgcaag tttgattatt ggagaagtta
     1741 ttttcaagag tttgagcttg gcagagcgtt tggttactat cgttgtaggt tctatcgctt
     1801 atcaattttt agtgtgggca gttatcgcac ttggctttaa tacaagttac cttcgtttat
     1861 acagtgcctt gattttagca gtctgcctca tgattccaac atttaagcaa acaatcttga
     1921 aaggagccaa gttaagcaaa tgacagcaat tgtagaatta aaaaatgcaa ccaaaatcgt
     1981 taaaaatggc tttgatgaag aaaagattat tttaaatgat gtttccttag aaatttttga
     2041 acgggacttt atcacgattt tgggcggaaa tggtgctgga aaatcaaccc tctttaacac
     2101 tatagcaggg accttatcac taactagtgg aactatccgt attttaggtg aagatctcac
     2161 taagttttca tccgagaagc gtgccaagta cctgtctcgt gtcttccaag atccaaagat
     2221 gggaacagct ccccgtatga cggtcgctga aaatctttta atcgccaagt ttcgtggtga
     2281 aaagcgtgga ttgttaccac gacgcttgac tagctataag gatgaatttc aggcaaccat
     2341 tgaaaaagta ggaaatggtc ttgagaaaca cttgaataca ccgattgagt tcttatcagg
     2401 tggacaaaga caggctttga gtctcttgat ggcaaccttg aagcgacctg aattactctt
     2461 gttagacgag catactgcag ctcttgatcc aaagacaagt gttgccctca tggaattgac
     2521 agatgaattt gtcaagaagg atcaattgac agcgcttatg attactcatc atatggaaga
     2581 tgctcttaag tatggcaatc gcttaattgt catgaaagaa ggacaaatta ttcaagattt
     2641 gaaccaagaa gaaaaagcaa aaatgaaaat ctctgattat tatcaactat ttgaataaag
     2701 tagggaaaat gagtgaaatg gtttactttt tttctgaaat aa
//
LOCUS       DAVDHZ010000082         2692 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000082 DAVDHZ010000000
VERSION     DAVDHZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.083"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>2692
                     /locus_tag="VUR46_002131"
     CDS             <1..>2692
                     /locus_tag="VUR46_002131"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457474.1"
                     /translation="DVSTVSADRKAKIEVVYPGNASATDTVVKELEVSLPTYHSTAKS
                     TEYTRTIGEAYASTDASDYVETTPNTPRGTEYAWKTDETGNQAYGSSTWGGANGDWLG
                     KKTNKVKVYYPNADGGNEKSEVLAEETEEITFITKPAKPSITSDLTWASGTRTTVEVG
                     NVTSGTRVVLYDEQGNELGHTDVAKGANYATPTTASITPTKALPTGKVYVKTIYMPDT
                     ADQRVESEKSDEATAKTNTLTAKGIIQTLAGPGNIGGVGTLDAATLGKLLRQENGGTD
                     FTGATAEWKDKTNLEKGNGGSRVEHLLVQLKGHSEKQDVAITVTSLTPPSAKAVLKSK
                     GADLTNDNLADYVTAEGQGTLSWEGNPAKVEVGQALPRIKVTYPTTGVAITDITDQYV
                     DAKVYSLEANSNAKTRVTVGDAFDPSAGDYVQTVANTADLPRTGVSHAWKDGNKPTSA
                     TVGKATYTVVTSFGNDADVPAELRGQDVETQVEVTVLSTKPSKPEASQNRTDLSITVV
                     VGKDDATKAEITFKDELDQEHTVSFTKGANGQWDKDDANSQPTVQIINNADGTATVHM
                     TGGTAKAGSTVVTKQQKADSDFSDISELVVKEHLKGATVTTKDDGSVEVVVPKEADTA
                     TVSYVPEGQTQAKTVTITKGQDGNWTGPADSDLVIKKDDATGRVTVTVPADKVADGST
                     VTGRVDSATGLSPEVEVKGKAPQPSEFSHHVRDNGDEVITLPQNADSVTLNYPVSDAN
                     VKTVTISKGQDGTWTAPADSDLVVKKDDATGSVTVTVPADKISGNRTITASAKAGSGD
                     GESKERTFTTTVVERQAPTVSEVTVAANGTLSAEQINAAVTAPKKVSAVAAEALKQVA
                     AGSNTEIPVTVTYADGSTETVQLAVYSKQVTPSTVGFQQK"
BASE COUNT          933 a          572 c          670 g          517 t
ORIGIN      
        1 cagatgtctc tacagtctct gcagaccgta aggctaagat agaagttgtc tacccaggta
       61 atgcttcagc aacagataca gttgtgaaag aattagaagt atcacttcca acttaccatt
      121 caacagctaa gtctacagag tatacacgta ccattggtga agcttacgct tcaaccgatg
      181 cgtcagacta tgtagaaacc actccaaaca caccaagagg aacggaatat gcatggaaga
      241 cagatgaaac tggcaaccaa gcctatggct catcaacttg gggaggggca aacggtgact
      301 ggctcggtaa gaagaccaat aaggttaaag tttactatcc aaatgcggat ggtggcaatg
      361 agaaatctga agtcttggca gaagagacag aggaaatcac tttcatcacc aaaccagcca
      421 aaccaagcat tacaagtgac ttgacatggg caagtggtac tagaacgact gtcgaagttg
      481 gcaacgtgac aagcggtaca cgggtagtct tgtatgatga gcaaggtaac gagctcggac
      541 atacagatgt agccaaagga gctaattacg caactccaac cacagcaagt atcacaccaa
      601 ccaaggctct accgacaggt aaagtctatg tgaagacgat ttacatgcca gacactgcag
      661 atcaacgtgt agagtcagag aaatcagatg aagcgactgc taaaaccaat accctaacgg
      721 ctaaaggaat tatccaaacg ctggcaggcc caggtaacat tggaggagtc ggcacgcttg
      781 atgcagctac tttaggtaag ttgttgagac aagaaaatgg tggtacagac ttcacaggag
      841 cgactgcgga atggaaagat aagacaaact tagagaaggg caatggagga agtcgagtag
      901 agcaccttct tgtccaacta aaaggacaca gtgagaaaca agatgtggct atcacagtca
      961 caagtttgac tccgccaagt gccaaagcag tcttgaaatc gaagggtgca gacttgacaa
     1021 atgataactt ggcagattac gtaacagcag agggacaagg taccctaagt tgggaaggta
     1081 atccagccaa ggtagaagtg ggtcaagctc ttccacgtat caaggttact tacccaacaa
     1141 caggtgtagc tattactgac atcactgatc aatatgtgga cgccaaagtc tacagtctcg
     1201 aggctaacag taacgccaag acaagagtga cggtgggaga cgcctttgac ccatcagcag
     1261 gagactatgt tcaaacagtc gctaatacag cagacttacc aagaactggc gtcagtcacg
     1321 catggaaaga tggcaacaaa ccgacatcag cgactgtagg aaaagccacc tacacagttg
     1381 ttacaagttt tggtaatgat gcagacgtac cagcagaact tcgaggacaa gatgtagaaa
     1441 cgcaagtaga agtaacggtt ctctcaacca aaccaagtaa accagaggcc agccaaaacc
     1501 gtacggattt atcgataaca gtagtagtcg gaaaagacga tgcgacgaag gcggaaatca
     1561 cctttaaaga tgaactggat caagaacaca cggtcagctt cactaaggga gccaatggtc
     1621 aatgggacaa agatgatgcc aatagtcaac caacggttca aatcatcaac aatgcagatg
     1681 gaacagcgac agttcatatg acaggcggca cagctaaagc aggcagcact gttgtaacga
     1741 aacaacaaaa agccgattca gactttagtg atatcagtga gttggttgta aaagaacact
     1801 taaaaggtgc cacagtaact actaaggacg atggttcagt agaagtggta gtaccaaaag
     1861 aagcagatac tgcgacagtc agctatgtcc cagaaggaca aacgcaagcg aaaacagtga
     1921 cgattaccaa aggtcaagat ggcaactgga caggtccagc cgattcagac ttagtgatta
     1981 agaaagatga tgcgacaggt agagtcacag tcactgtacc agcagataaa gtagccgatg
     2041 gcagcacagt tacaggaaga gtagacagtg ctactgggtt aagtccagaa gttgaagtga
     2101 aagggaaagc gccacaacca tctgaattta gtcatcatgt tcgagacaac ggcgacgaag
     2161 tgattacctt gcctcagaat gcggacagcg tgacgcttaa ctatccagta agcgacgcga
     2221 acgtgaagac agttacgatt agtaaaggtc aagatggcac ctggacagct ccagccgatt
     2281 cagacttagt tgttaagaaa gatgatgcga caggcagcgt caccgtcacg gtaccagcag
     2341 ataagatttc gggtaaccga acgattacag caagtgctaa agcaggaagt ggcgatggag
     2401 aaagtaaaga acgtaccttt acaacaacag ttgtagagcg tcaagcacca actgtttcag
     2461 aagtgacagt agcagcgaat ggcacactaa gtgcagaaca gatcaatgcg gctgttacag
     2521 ctcctaagaa agttagtgcg gttgcggcag aagccttgaa gcaagtagca gcaggcagta
     2581 acacagagat tccagttaca gttacctatg cggatggctc aacagaaacc gttcagttgg
     2641 cagtatactc taaacaggta acaccaagta cagtcggctt ccaacaaaaa ga
//
LOCUS       DAVDHZ010000083         2633 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000083 DAVDHZ010000000
VERSION     DAVDHZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.084"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..342)
                     /locus_tag="VUR46_002132"
     CDS             complement(<1..342)
                     /locus_tag="VUR46_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET5457475.1"
                     /translation="MTKDWTFDQSLDDNTPTSSTEERAKIAALFHKEEKEETGEVNYV
                     AAFEMEQQKAKEKSVSKPKVQEQSTPKEVPSSTITSDYKQHLANVMAQNNEDILQSQK
                     KIEELNQLIDDK"
     gene            complement(339..572)
                     /locus_tag="VUR46_002133"
     CDS             complement(339..572)
                     /locus_tag="VUR46_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457476.1"
                     /translation="MSVIERLAERVARQEEKVAKETEKLGTYREQLQAAMYSIFVKRQ
                     QSSHLTFDEALNQAFGKQENHSQVIENRNEETE"
     gene            complement(626..1714)
                     /locus_tag="VUR46_002134"
     CDS             complement(626..1714)
                     /locus_tag="VUR46_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET5457477.1"
                     /translation="MTRIEAVKQKAILEVAESLGYSFKRLSGQVYEHPEHDSFRIFAD
                     TNTFKWFSRDIQGDVIDFVQLITGVTFKEALSYLETGDFEQTKMVEETYQPFRYYLRE
                     EPFYQARIYLNDIRGLSDDTINAFGRQGLLAQAHYQTKIFQESVLVFKSYSHHGQLEG
                     ASLQGLVKNNERHDRDYLKKIMKGSHGYVGMSFDIGKPERLIFCESVIDMMSYYQLHQ
                     NQLSDVRLVSMEGLKLSVIAYQSLRLVAEEQGKLEFLDTVKPSRLTHYLHAIQETTTF
                     FQTHPSLITLAIDNDGAGRDFCQKLSEKSLPIETDLPPLQELETKADWNDVVKSQKDL
                     SLKDMIQSAKLQVIRSNPPPRKNTALEL"
     gene            complement(1753..2391)
                     /locus_tag="VUR46_002135"
     CDS             complement(1753..2391)
                     /locus_tag="VUR46_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET5457478.1"
                     /translation="MLNKMKVSFLLGLGGLAVMSFVVMMGYTIGSQSVTHHMQKQIQT
                     EAHKLLTQEKEKEKASVLSDELVKEFLTQYYTKGKLGENNNRIKLYMTDSAYKEEVAR
                     QEDSINQVYKDYMLDYRFETAQIYVNTEANEALAEVSYQVVYVSDVSDKAQKSTQTET
                     KSLKLSYTKMSDKFLVKQVTVWNGKLENLKEVSDGADSSIPDIQGTTTSETN"
BASE COUNT          729 a          556 c          463 g          885 t
ORIGIN      
        1 tttgtcatca atcaactggt tcagctcttc gattttcttt tgactttgaa gaatgtcctc
       61 attgttttga gccatcacat tggctagatg ttgcttgtag tcactggtaa tggttgaaga
      121 gggcacttct tttggtgtgg attgctcttg aacttttggt tttgaaactg atttctcctt
      181 agctttttgt tgctccattt caaaggctgc cacataatta acttctccag tttcttcttt
      241 ctcttcctta tgaaataggg ctgcaatctt cgcacgttct tctgtggaag acgttggtgt
      301 gttatcatct agggattggt caaaagtcca atcttttgtc attctgtttc ctcatttcta
      361 ttttcgatta cctgtgaatg attttcctgc ttaccaaacg cctggtttaa agcctcatca
      421 aaagtaagat gactcgactg ctgacgcttg acaaatatgc tatacatagc tgcctgtaac
      481 tgctcacgat aggttcctag cttttccgtt tctttcgcaa ctttttcctc ttgcctagct
      541 actctttcag ccaggcgttc aatcacactc atagggtgtc ctccttatca ctttctagat
      601 taagctaaga aacttgattt tgttatcaca actctaaagc ggtatttttt ctaggaggag
      661 gattgcttcg gataacttgt aacttggccg attggatcat atcctttaga gaaaggtctt
      721 tctgactttt cacgacatca ttccaatcag ctttagtttc cagttcctgt aatggtggta
      781 agtctgtttc aatgggaagg cttttctcag ataatttctg acaaaagtct cgccctgctc
      841 catcattatc aatagctaag gttatcagac ttgggtgagt ctgaaaaaaa gtggttgtct
      901 cttgtatggc atgaaggtaa tgcgttaatc gacttggttt tacagtatct aaaaactcaa
      961 gtttgccttg ttcctcagct actaatcgta aggactgata cgcaatcaca gagagtttta
     1021 gaccttccat agaaactaaa cgcacatctg ataactgatt ctgatggagt tgataatagc
     1081 tcatcatgtc aatcactgat tcacaaaaga taaggcgttc aggctttcct atatcaaaac
     1141 tcatcccaac ataaccatga gaacctttca tgattttctt gagataatct cgatcatgtc
     1201 tctcattatt tttaacaagc ccctgcaaac ttgccccctc tagttgccca tgatgactgt
     1261 aactcttaaa aacaagaact gattcttgaa agatctttgt ctgataatga gcttgggcta
     1321 acagcccttg tctgccaaaa gcattgatag tgtcatcgct taaaccacga atgtcattca
     1381 agtatatccg tgcttggtaa aatggttctt cccttagata atagcgaaag ggttggtaag
     1441 tctcttcaac catcttagtc tgttcaaagt cccctgtttc aaggtaagac agagcttctt
     1501 taaaagtcac tcctgttatt aactgaacaa aatcaatcac gtctccctgt atgtcacgtg
     1561 aaaaccattt aaaagtattg gtatccgcaa aaatcctaaa ggaatcgtgt tctggatgtt
     1621 catagacttg ccctgatagt cgtttaaaag aataacctag actttctgca acctctaaga
     1681 ttgctttttg tttcactgct tcaattcttg tcatctcatc tccctatcaa aaaagcagaa
     1741 gggtaactcc tgctagttgg tctcacttgt agtagtgcct tgaatatctg gaatgcttga
     1801 atcagctcca tcagaaactt cttttaagtt ctctagcttt ccgttccaaa cagttacctg
     1861 cttgacaaga aatttatctg acattttggt ataagatagt ttaagagatt tcgtttctgt
     1921 ttgtgtactt ttctgagcct tatcactaac atctgacaca taaacaacct gataggatac
     1981 ttccgcaaga gcttcatttg cttctgtatt gacatagatt tgagcagtct caaagcgata
     2041 atccaacata tagtccttat agacctgatt gatggaatct tcttgacgag ctacttcttc
     2101 cttataagca gagtcggtca tatagagctt aatacggttg ttgttctccc ccagctttcc
     2161 cttagtgtag tattgggtga gaaattcttt gaccaactca tctgagagga cacttgcttt
     2221 ctccttttct ttctcttggg tcaatagttt atgagcttca gtctggattt gtttctgcat
     2281 gtgatgggtc acagactgag aaccaatagt gtagcccatc atcaccacaa agctcatgac
     2341 tgctagacca cctaaaccaa gcaaaaaact cactttcatt ttatttaaca tcaatagtgc
     2401 catctccttt ttccgtaaga tagcaccatc ataacaagat tgacttggaa aagttatcac
     2461 aaaaaagaaa agagcctagg acaaaatagt tctcgaccac aaaaaagcgg ctctataata
     2521 tttgtagtgg gtaaatccac tatagatatt atggagccta ttttattgta gaaaaaaagt
     2581 cccatatgac ctataatgaa aagcgacaaa acaactcatt agaaagattc ata
//
LOCUS       DAVDHZ010000084         2592 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000084 DAVDHZ010000000
VERSION     DAVDHZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.085"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            191..1387
                     /gene="tuf"
                     /locus_tag="VUR46_002136"
     CDS             191..1387
                     /gene="tuf"
                     /locus_tag="VUR46_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET5457479.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            1771..2592
                     /locus_tag="VUR46_002137"
                     /pseudo
     CDS             1771..2592
                     /locus_tag="VUR46_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          840 a          503 c          516 g          733 t
ORIGIN      
        1 gaaaactcct tgaaggataa gtctatttag tactttctat taattagtta aatttttacc
       61 aagaataatt cacaaaaacg ttgtaaaaca cttgcaattt agctgaaatt tgataaaata
      121 gtaaggaaag ttagactgta ttgcctactg tctatctata aaatatattt tattggaggc
      181 ttttactcaa atggcaaaag aaaaatacga tcgtagtaaa ccacacgtta acattggtac
      241 tatcggacac gttgaccacg gtaaaactac cctaactgca gctatcacaa ctgttttggc
      301 acgtcgcttg ccttcatcag ttaaccaacc taaagactat gcgtctatcg atgctgctcc
      361 agaagaacgc gaacgcggta tcactatcaa cactgcgcac gttgagtacg aaactgaaaa
      421 acgtcactac gctcacatcg acgctccagg acacgcggac tacgttaaaa acatgatcac
      481 tggtgctgct caaatggacg gagctatcct tgtagtagct tcaactgacg gaccaatgcc
      541 acaaactcgt gagcacatcc ttctttcacg tcaggttggt gttaaacacc ttatcgtctt
      601 catgaacaaa gttgacttgg ttgacgacga agaattgctt gaattggttg aaatggaaat
      661 ccgtgaccta ttgtcagaat acgacttccc aggtgacgat cttccagtta tccaaggttc
      721 agcacttaaa gctcttgaag gtgactctaa atacgaagac atcgttatgg aattgatgaa
      781 cacagttgat gagtatatcc cagaaccaga acgtgacact gataaaccat tgcttcttcc
      841 agtcgaggac gtattctcaa tcactggacg tggtacagtt gcttcaggac gtatcgaccg
      901 tggtatcgtt aaagtcaacg acgaaatcga aatcgttggt atcaaagaag aaactcaaaa
      961 agcagttgtt actggtgttg aaatgttccg taaacaactt gacgaaggtc ttgctggaga
     1021 taacgtaggt gtccttcttc gtggtgttca acgtgatgaa atcgaacgtg gacaagttat
     1081 cgctaaacca ggttcaatca acccacacac taaattcaaa ggtgaagtct acatccttac
     1141 taaagaagaa ggtggacgtc acactccatt cttcaacaac taccgtccac aattctactt
     1201 ccgtactact gacgttacag gttcaatcga acttccagca ggtactgaaa tggtaatgcc
     1261 tggtgataac gtgacaatcg acgttgagtt gattcaccca atcgccgtag aacaaggtac
     1321 tacattctct atccgtgagg gtggacgtac tgttggttca ggtatggtta cagaaatcga
     1381 agcttaattc gatttagttc ccagaagaac aattatttaa gtcagacact aaaagaatct
     1441 tgcttggcaa ggttcttttt ttagatattg aactaatact caatgaaaat caaagagcaa
     1501 actataatat attgaaacta gaatagtaca catctacttc taaaacattg ttagaaatcg
     1561 atttgattgt cttgattgat ttgtcttgtt cttatttcat tttgttatag aaagttagct
     1621 gcagactgct caaaacactg tttttaggtt gtagatagaa ctgacgaagt cagtaacatc
     1681 tatacgacaa ggcgaagctg acgcggtttg aagagatttt cgaagagtat aatactagac
     1741 taaactcaaa aagcattata caatagtaat atgaaatcaa ttaaagaaga aatccaaacc
     1801 atcaaaacac ttttaaaaga ctctagtaca gctaaatatc ataaacgcct tcaaatcgtt
     1861 ctatttcgtc tgatggggta aatcttataa agagattata gagcttttag agtgtaatca
     1921 aacaacgatt tggcgaaatg taaaaaaata tgaggagttc ggactcgact ctctccttca
     1981 agaaacacgt ggtggtcgta accatgcata tatgacagtt gaggaagaga aagcctttct
     2041 tgcccgccat ttgaaggcta cagaggcagg agaatttgtt acaattgatg ccttatttca
     2101 ggcttataaa aaggagttag gtcgttccta cacacgtgat gccttctatc aactgttgaa
     2161 gcgccatggt tggcgaaata ttatgccacg tccagaacat cttaggaaag cagacgctca
     2221 aaccattgtc gcgtctaaaa ataaaatctc aattcaagaa gacgagaaag cgctttaaaa
     2281 ccagtagacg ttttcgtaag gttcgcttga tgtaccaaga tgaggctggt ttcggtagaa
     2341 tcagtaaact gggatcttgt tgggctccaa taggagtagg tccacatatc catagtcact
     2401 atatacgaga atttcgctat tgttatggag ctgttgatgc ccatacaggc gaatcatttt
     2461 tcttaatagc tggtggatgt aatactgagt ggatgaacgc ctttttagaa gagctttcac
     2521 aagcttatcc agatgattat cttttactcg ttatggacaa tgctatatgg cataaatcaa
     2581 gtaccttaaa ga
//
LOCUS       DAVDHZ010000085         2461 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000085 DAVDHZ010000000
VERSION     DAVDHZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.086"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..1302
                     /locus_tag="VUR46_002138"
     CDS             <1..1302
                     /locus_tag="VUR46_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
                     /protein_id="HET5457480.1"
                     /translation="QKHLEEVKTSHNGLDSLQSHEQDYSGNAKEMKDLDKKIEEKIAG
                     IMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEEGV
                     AKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINMLV
                     KLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDGTF
                     TVSTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLENNY
                     KVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYIVEVPILEKENQTDKPSI
                     LPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLTETRNSTSNSTLEEAPAVDPVQEKV
                     EKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKNLSDLIA"
     gene            1528..2088
                     /locus_tag="VUR46_002139"
                     /pseudo
     CDS             1528..2088
                     /locus_tag="VUR46_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            2132..2272
                     /locus_tag="VUR46_002140"
     CDS             2132..2272
                     /locus_tag="VUR46_002140"
                     /inference="COORDINATES: protein motif:HMM:NF016182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET5457481.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAVA
                     KV"
     gene            2342..2461
                     /locus_tag="VUR46_002141"
                     /pseudo
     CDS             2342..2461
                     /locus_tag="VUR46_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT          943 a          355 c          449 g          714 t
ORIGIN      
        1 caaaaacatt tagaggaagt taaaactagt cataatggat tagattcttt gcaatctcat
       61 gaacaggatt attcaggtaa tgccaaagaa atgaaagatt tagataaaaa aatcgaagaa
      121 aaaattgctg gcattatgaa acaatatggt gtcaaacgtg aaagtattgt cgtgaataaa
      181 gaaaaaaatg cgattattta tccgcatgga gatcaccatc atgcagatcc gattgatgaa
      241 cataaaccgg ttggaattgg tcattctcac agtaactatg aactgtttaa acccgaagaa
      301 ggagttgcta aaaaagaagg gaataaagtt tatactggag aagaattaac gaatgttgtt
      361 aatttgttaa aaaatagtac gtttaataat caaaacttta ctctagccaa tggtcaaaaa
      421 cgcgtttctt ttagttttcc gcctgaattg gagaaaaaat taggtatcaa tatgctagta
      481 aaattaataa caccagatgg aaaagtattg gagaaagtat ctggtaaagt atttggagaa
      541 ggagtaggga atattgcaaa ctttgaatta gatcaacctt atttaccagg acaaacattt
      601 aagtatacta tcgcttcaaa agattatcca gaagtaagtt atgatggtac atttacagtt
      661 tcaacctctt tagcttacaa aatggccagt caaacgattt tctatccttt ccatgcaggg
      721 gatacttatt taagagtgaa ccctcaattt gcagtgccta aaggaactga tgctttagtc
      781 agagtgtttg atgaatttca tggaaatgct tatttagaaa ataactataa agttggtgaa
      841 atcaaattac cgattccgaa attaaaccaa ggaacaacca gaacggccgg aaataaaatt
      901 cctgtaacct tcatggcaaa tgcttatttg gacaatcaat cgacttatat tgtggaagta
      961 cctatcttgg aaaaagaaaa tcaaactgat aaaccaagta ttctaccaca atttaaaagg
     1021 aataaagcac aagaaaactc aaaacttgat gaaaaggtag aagaaccaaa gactagtgag
     1081 aaggtagaaa aagaaaaact tactgaaact aggaatagta ctagtaattc aacgttagag
     1141 gaagctccag cagtagatcc tgtacaagaa aaagtagaaa aatttacagc tagttacgga
     1201 ttaggcttag atagtgttat attcaatatg gatggaacga ttgaattaag attgccaagt
     1261 ggagaagtga taaaaaagaa tttatctgat ctcatagcgt aaggaatagc agtagaaaaa
     1321 gtctgaatca aaaatgaagt tctttcaaaa gttagaaata aaactctgac tttgggagaa
     1381 tttcatttta ttattaatat ataaaatctc ttgacataca acttaaaaag aggtggaata
     1441 tttactagtt aattaattgg ttaatcaatt tatttaatca tttaataatg aagacatcat
     1501 ataaataatt atagaaatga ggtaattatg aaatttaaaa agaaatatat agcagctgga
     1561 tctgttgtta tcctttcctt aagtctgtgt gtttatgctc tgaaccaaca tagctaacag
     1621 gccaatacag ataaaaatcg tgtttcatat gtaaacagta ataaagacac taagaagact
     1681 gaaaatttga ctccagacta ggttagtcaa aaagaaggaa ttcaagcaaa acaaattgtt
     1741 attaagatta caggtcaagg ttatgtaact tctcatggcg atcattatca ctactataat
     1801 gataaagttc cttttgatgc gctctttagt gaagagctat taatgaaagc ccccaactat
     1861 cagccgaaag atcaagatat cgtcagttag gttaagggag gatatattat taaggtagat
     1921 ggaaagtatt atgtttacct taaagatcaa gctcatgcag aaaatgtacg aacaaaagat
     1981 gaaatcaatc gccaaaaaca agaacatggt aaagacgata aaggagctag tgcagaagta
     2041 tctgtagcaa aattacaggg acgttatact accgatgatg gttatatata gtgagttgaa
     2101 tttagaatag cacatcatag tttctaaatc attgctagaa attactttaa aatctcctta
     2161 tcaatttgct catattctat ttcaatctac tatagtacca catggtggtc actatcattt
     2221 cattcctgag agtgacttgt cggcaggtga attagcagtc gcaaaagtat aattatcagg
     2281 gaatactaca gctctcagtc aatctttgcc ggtgacaccg aataatggtg tttctgcagt
     2341 agatgatggt tatgtcttta accctaatga tattgtcaga gatacaggtg atgcttatat
     2401 agtaagacat ggggatcact atcactatat tcctaagtca tctcttaaca atcccccatc
     2461 a
//
LOCUS       DAVDHZ010000086         2127 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000086 DAVDHZ010000000
VERSION     DAVDHZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.088"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            131..2110
                     /locus_tag="VUR46_002142"
     CDS             131..2110
                     /locus_tag="VUR46_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5457482.1"
                     /translation="MKTRKVLALVGVTLLAAGVLAACSGGSGAQGEKTFAFTYETHPD
                     NLNYLTTGKAATSEITSNVIDGLLENDKYGNLVPSLAEDWSVSKDGLTYTYKIRQDAK
                     WYTSEGEEYALVKAQDFVTGLKYATDKKADALYLVQDSIKGLDAYAKGEITDFAQVGI
                     KALDDQTVQYTLNKPETFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPY
                     LLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLY
                     PTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSEEQKTSTKKALLN
                     KDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGELVKEKLVTY
                     GDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQR
                     VQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFAD
                     PSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRYD
                     KYAAAQAWLTDSALIIPTTSRTGRPILSKIVPFTIPFALSGNKGTSDPVLYKYLEIQD
                     KAVTADEYQKAQEKWMKEKAESNKKAQEELAKHVK"
BASE COUNT          737 a          371 c          441 g          578 t
ORIGIN      
        1 agtttcaatc aactgtaaat atgcttttca gaatagatca aatataacaa ataactctta
       61 aaattcagaa aattctattg acagaacttg aaaaagggtc tataatgaat aaaaaacaaa
      121 ggagaatgct atgaaaacaa gaaaagtatt ggctcttgtg ggagtaactt tattagcagc
      181 tggtgtttta gctgcttgtt ctgggggttc aggcgctcaa ggtgaaaaga cctttgcgtt
      241 tacctacgaa acacatccag ataatctcaa ctatttgaca actggtaagg cagcaacttc
      301 tgagattact agtaatgtga ttgatggatt gcttgaaaat gataaatacg ggaaccttgt
      361 tccttcattg gcagaagact ggtcagtttc taaggatggc ttgacttata cttataagat
      421 tcgtcaggac gccaagtggt atacatctga gggagaagag tatgctcttg ttaaggctca
      481 ggactttgtg acaggtctta aatatgcaac agataagaaa gcggatgctc tttacttggt
      541 acaggattca atcaaaggtc tggatgccta tgcaaaaggt gaaatcacag actttgctca
      601 agttgggatt aaagcccttg acgatcagac agttcaatac accttgaaca aacctgaaac
      661 tttttggaat tctaaaacaa ctatgggtgt gcttgcgcca gtcaatgaag agtttttgaa
      721 ttcaaaaggg gatgattttg ccaaagctac ggatccaagt agtctcttgt ataatggacc
      781 ttatttgttg aaatccattg tgacaaaatc ctctgttgaa tttgcgaaaa atccgaacta
      841 ctgggataag gacaatgtgc atattgacaa ggtcaaattg tcattctggg atggtcaaga
      901 taccagcaaa cctgcagaaa actttaaaga tggtagcctt acagcagctc gtctctatcc
      961 aacaagtgca agtttcgcag agcttgagaa gagtatgaag gacaatattg tctatactca
     1021 acaagactct attacgtatc tagttggtac aaatattgac cgtcagtcct ataaatacac
     1081 atctaagacc agtgaagaac aaaaaacatc gactaaaaag gctctcttaa acaaggattt
     1141 ccgtcaggct attgcctttg gttttgatcg tacagcctat gcctctcagt tgaatggaca
     1201 aactggagca agcaaaatct tacgtaatat ctttgttcca ccaacatttg ttcaagcaga
     1261 tggtaaaaac tttggtgagt tggtcaaaga gaaattggtc acttatgggg atgaatggaa
     1321 ggatgttaat cttgcagatt cacaagatgg tctttacaat ccagaaaaag ccaaggctga
     1381 atttgctaaa gctaaatcag ccttacaagc agaaggtgtg acattcccaa ttcatttgga
     1441 tatgccagtt gaccaaacag caactacaaa agttcagcgc gtccaatcta tgaaacaatc
     1501 cttggaagca actttgggag ctgataatgt cattattgat attcaacaac tacaaaaaga
     1561 cgaagtaaac aatattacat attttgctga aaatgctgct ggtgaagact gggatttatc
     1621 agataatgtc ggttggggtc cagactttgc cgatccatca acctaccttg atatcatcaa
     1681 accatctgta ggagaaagta ctaaaacata tttagggttt gactcagggg aagataatgt
     1741 agctgctaaa aaagtaggtc tatatgacta cgaaaaattg gttactgagg ctggtgatga
     1801 ggctacagat gttgctaaac gttatgataa atacgctgca gcccaagctt ggttgacaga
     1861 tagtgctttg attattccaa ctacatctcg tacagggcgt ccaatcttgt ctaagatagt
     1921 accatttaca ataccatttg cattgtcagg aaataaaggt acaagcgacc cagtcttgta
     1981 taaatacctt gaaattcaag acaaggcagt tactgcagat gaataccaaa aagctcaaga
     2041 aaaatggatg aaagaaaaag cagaatccaa taaaaaagcg caagaagaac ttgcaaaaca
     2101 tgtgaaataa aataaaaaga gactgaa
//
LOCUS       DAVDHZ010000087         2122 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000087 DAVDHZ010000000
VERSION     DAVDHZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.089"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(28..813)
                     /locus_tag="VUR46_002143"
     CDS             complement(28..813)
                     /locus_tag="VUR46_002143"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET5457483.1"
                     /translation="MKHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVNEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRGSSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            complement(1163..1591)
                     /locus_tag="VUR46_002144"
                     /pseudo
     CDS             complement(1163..1591)
                     /locus_tag="VUR46_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901186.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            1866..>2122
                     /locus_tag="VUR46_002145"
     CDS             1866..>2122
                     /locus_tag="VUR46_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5457484.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDITNKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPARILLRKRRFKCYHCS"
BASE COUNT          634 a          484 c          344 g          660 t
ORIGIN      
        1 aaattcaaag aatgatgcaa gtatttttta ttttcctgta aatttaggtc ttcttctctc
       61 cgaatgagct cgcactcctt ctttgaaatc ctctgtttga gctaaggatt tctgtaggtt
      121 cagttctaaa gtagcgtaac cctgccagtc tttaaattgg ctctcccaaa ccaacttctt
      181 aatggcagca taggaattac ttgaaccacg tcttaatttt ttaagaagct gttctctcgt
      241 cttttcaagt ttttcagctt cagaaacgcg gtaaaccaac ccccattcta gggctttttc
      301 tgccgttaaa gcctctcctg tcatagctaa ttgagcagca cgcgtcacac cgatactgcg
      361 gcttaagaga tgaattcccc ctgcatctgg agccaaacca acaccaacaa aggcttggat
      421 aaacttagcc ttatccgtcg ccaaacagaa atctgccgca acagccatat tcgctgcggc
      481 acctgcaaca gcaccgtcaa cttccattaa aacaggtttg gctatttgct tgattttata
      541 agaaatcgta ttgaccaact ctgcgatttt tgtcagtgat ggaatatcat cctcattcac
      601 tgcccgcttc atctctacca aatctccccc aactgagaag acctttccat tggcattgat
      661 taagataaaa tgcacagctg gattttcttc tgccaaagtc agagcttcta aaatctcctc
      721 acacatggga atatgaaaac catttgcgac ctcaggacgg ttcaaggtaa ggattgccaa
      781 gtcctcttca agctgataaa taatgtgttt catcagagct cctttttatt ttataagcag
      841 tttatactct tcgaaaattt cttcaaaccg cgtcagcttc catctgcaac ctcaaaacag
      901 tattttgagc tgacttcgtc agtttcatct acaacctcaa agcagtgctt tgagcagtct
      961 gcggctagct tcctagtttg ctctttgatt ttcattgagt gttaaattat ttcactttca
     1021 aagtatatct tttttaggag cagaaagcaa gaaaaaatcg actgaaagtg tctcagccga
     1081 taagaaaggc tcgctttagg ctagaaagca tcttattgct ctggcacata atgagcaacc
     1141 tggcttgttt ttgcaaaagc cattatttca aatcctccaa aaattgataa agattggtca
     1201 aacctttgct catgacatcc atttcttcct tactcacacc atcaatgatt ttttcaacca
     1261 tggccttgtg gaagcgttta tgtagcctat gaaccaagcg acccttcttt gtcaaatgta
     1321 gatgcaccac acgacgatcc tgctctgagc gaatgcgttc aatgtaagcc ttgcgttcga
     1381 gattattcaa actagtcgta actgtcccaa gaatcaccag caactctttt gacacttgac
     1441 ttggtgtcac gtctgggaat ttcccaatca catcaatcgt atgcatttct ttgatggaga
     1501 tatccttgaa acgactacct ctcaagttca cttcctcaat gacaaggaca ttgttaaata
     1561 ttcattaatt cgttggtagt ccatttttca tatccctcct tcttcaaaaa aacttttaca
     1621 atcaaaacat ttgacaagag aattatatca aagctcaaac aatgatgcaa gtatttttta
     1681 ttttcctgta aatttaggcc ttcttcgttt gaaaacgctt atatatactc ctaaggaaag
     1741 agactctata atatttgtag tgggtaaatc cactatagat attatggagc ctatttttgt
     1801 gtagaaaaaa agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga
     1861 tttatatgga acaattacat tttatcacaa aattactaga cattaaagac cctaatatcc
     1921 agattttaga catcaccaat aaggatacac acaaggaaat catcgccaaa ctggactacg
     1981 acgccccatc ttgccctgag tgtggaaacc aattgaagaa atatgacttt caaaaacctt
     2041 ctaaaattcc ttatcttgaa acgactggta tgcctgctag aattctcctt agaaagcgtc
     2101 gtttcaagtg ttatcactgt tc
//
LOCUS       DAVDHZ010000088         2083 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000088 DAVDHZ010000000
VERSION     DAVDHZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.090"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(179..982)
                     /locus_tag="VUR46_002146"
     CDS             complement(179..982)
                     /locus_tag="VUR46_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET5457485.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1261..2016)
                     /locus_tag="VUR46_002147"
     CDS             complement(1261..2016)
                     /locus_tag="VUR46_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET5457486.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
BASE COUNT          679 a          415 c          316 g          673 t
ORIGIN      
        1 cgaattaagg taaaactaaa aggacttagc cctgtgcaat acagaactaa atccttcgga
       61 taaattaatt gtctaactgt ttggggtcag tacattttaa cacttgatac tatgcgtttt
      121 attgtgggaa tgtttacttc attttttcct aaaattcaat gtttactcag tatttggatt
      181 atgaaaaatc gaggtctaaa tctagataca ttttttctga agacaaatca ttttgaccac
      241 cgagcaagag attttcaaaa aaagctgtta aaaactcagg acgtcgctgt aaaatctttg
      301 cattatctaa taccaaggca tcacgaaaat acttggaatg ttgctgaaat ggtatattat
      361 caatatcaaa accaaactca cgaagatact gaatcaaaaa gaccgttact gtccgagtgt
      421 ttccttcgcg aaatggatga atctgccaga ttcctgaaat aaaatgctgg atttgtttaa
      481 ccacatccgc ctgagttagt gtcgcatatg caacttgttt ttcctgatta aaatcataat
      541 ctaaggtcat ttgaatcatg gagtaatcag agtacacaac actttcacca ttcaaaacag
      601 gttcattctt tgtgatattg gtctgacgaa attgccccac cggaatagag ggttcaaata
      661 tatcttgaaa caactcctta tgaatagcaa gtaaggtcgc aggactaaag ctaaagcctc
      721 ttcgagacaa tagttctaca atacgtagag aaaccaagtc tgcctcttcc gtacttgcat
      781 caatagtatg gtgataagcc gttgcatcct cataaacctg ctcataagtc agttctcccc
      841 gggactgttt ctcagccaaa gattccatat acgctgatgg cactagattg tcaactttct
      901 gcagaccaaa acctatccgc cataaatcac gcttcgcttc ataagacaag tttggattgt
      961 caatgttgta agttggttgc atagaaatat cctttcaatt gtttttcttc attaccagta
     1021 aatcacgaaa ttggttggaa actggcttaa actataaaaa gtcctcacaa taggttctat
     1081 gatatatata tatatacttc atgtaaataa taaaagagtt ataatcagca ctactgataa
     1141 attcaatacc gatttcgcca tcttaaaact tagtcaaacg aataccgttg atttccagtt
     1201 cattaagtcg ttgacctgtc aagacttctc gttccttcaa ctggaaaagt taagggggaa
     1261 ctaatacaaa tcctctacgc ttctatattc aatgatttca tttttgataa tattcttttt
     1321 aaactcaaaa tgttttaaag gattatcgat taacactaac tttggaatat catctagatt
     1381 tgtgaccaag gataaaataa aatccgattg aaactccttg actttttcaa attcttttgc
     1441 agttaaacgc acacgcccct tagattttcg gatacctttt acttcggcaa ggtaagaata
     1501 ctcttggaca tctacctgaa agtcatatcc atcaccataa agacgggcat cggttaactg
     1561 tccaccttgg aatttttctt ctttatcaaa atgaaggata aaataattct cagcctccat
     1621 tcccgtttcc tgtagacgtt tgaatttagt tcgaactatt ggtttttcaa cgatggttat
     1681 gcctgttttc ttcccttcac tggcaagtaa cattttaact atttcagcat aactatgaac
     1741 atcttcattt ccaaacatca tatcaattaa atctttacga aaacgataaa cttcagcttt
     1801 ctgccaccaa ccttttcgat tattgtcaaa ataaggatca aataaatcca ttctattttt
     1861 tacaactcca gttgtttcag caattcccag agaaaccaca tagcgataaa actccgactt
     1921 gctagagcat tgaaattctt ttataaaaag cttgtcaaac ttggcaagac cgtagccaat
     1981 taaatttaac aattcataat gagggtgttt ggacatcact ttctccatca atagatattg
     2041 atttcattat accaaaaaac acggcattac accatgtttc tat
//
LOCUS       DAVDHZ010000089         1944 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000089 DAVDHZ010000000
VERSION     DAVDHZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1944
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.091"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..1103
                     /locus_tag="VUR46_002148"
     CDS             <1..1103
                     /locus_tag="VUR46_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET5457487.1"
                     /translation="TLVKPFEQNVTDKDLLDAVNADHKKSAKLKDGTSYPTTDGFHDI
                     DLTVTYEDGSMENVSVKYKVTDTAKADIDTAAAEKKTAIEKTPNLTPEEINVAKRQVD
                     EALAEAKRKVGEATDQAGINRAKQEGLSSIDLVLDQALVQSFGRTNGRRSRRTPPRRS
                     RRSVGFVGNSQTGTTPSAVDKSELRTLVEDLERRLKELEGLSPEAQSILREAQAALAN
                     DSLTAQELAKLLAKVRQALNSIQAGTSADKSPSTSNSNKEAESAKEPTNATDVPLYGV
                     FGAAALSLLGALLFAVARKKNSQLDKLLRELDQLLVELEASDKDKKGLGKAKKLAKKA
                     RTFVDSQQKDPQKEAELISEIKTTLSQLREGV"
     gene            complement(1240..>1944)
                     /locus_tag="VUR46_002149"
     CDS             complement(1240..>1944)
                     /locus_tag="VUR46_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5457488.1"
                     /translation="RTQAIIRNHFLRYDRAVLCRVKIITMDMFIPYYDLARQLFPCAK
                     IVLDRFHIVQHLSRAMSRMRVQIMNQFHRKSHEYKAIKRYWKLIQQDSLKLSDKRFYR
                     PTFRMHLTNKEILDKLLSYSQDLKYHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHP
                     IFQTVFKTFLKDKEKIVNALQLPYSNAKLEVTNNLIKLIKRNAFGFRNFENFKKRIFI
                     ALNIKKERTKFVLSRA"
BASE COUNT          643 a          346 c          433 g          522 t
ORIGIN      
        1 ctacattagt caaaccattt gaacaaaatg ttacagataa agatttgtta gacgctgtaa
       61 atgctgacca caaaaaatct gctaagttga aagatggaac tagctatcct acaacagatg
      121 gtttccatga tattgatctt acagtgacat atgaggatgg tagtatggaa aatgtatcag
      181 tcaaatacaa agttacagat actgcaaaag ctgacattga taccgcagct gctgagaaga
      241 aaacagcgat tgagaagact ccaaacttaa ccccagaaga gattaacgtt gcgaaacgcc
      301 aggtagacga agctcttgca gaagcgaaac gtaaagtagg agaggcgaca gaccaggcag
      361 gaattaaccg agcgaagcaa gaaggcttat ctagtataga tctggttctg gatcaagctt
      421 tggttcaatc ttttggtaga actaatggta gaagaagtcg cagaactcct ccgcgccgct
      481 ctcgtagaag tgtaggattt gtagggaatt cccaaacagg tacaactcca tcggctgtgg
      541 acaagtctga acttcgtact ctggtagagg atctggaacg ccgcttgaaa gagttagaag
      601 gtctatctcc tgaagcacag agtatcttga gagaggcgca agcggctctt gctaatgact
      661 ccttaacagc tcaagaattg gcgaaactcc ttgccaaagt tagacaggct cttaattcta
      721 tacaagctgg cacatcagct gataagagtc cgtctacgtc aaactcaaat aaggaagcag
      781 aaagcgccaa ggaacctaca aatgcgacag atgtccctct atatggtgtc tttggagctg
      841 cagcactctc tcttctagga gctctcctct ttgcagtggc tcgtaagaaa aactctcaac
      901 tagataagct tttaagagaa ttggatcaac ttctagttga gttagaggct agtgacaagg
      961 ataaaaaagg tttaggcaag gctaaaaaat tagctaagaa agcaagaacc tttgtggata
     1021 gccagcaaaa agatcctcaa aaagaagcag aactaatttc tgaaatcaag actactctca
     1081 gtcaactcag agaaggagtc tagtcttgaa gaaaaaaact actttcaaaa atgcagtgag
     1141 tagttttgta gcgatgatga ggaaataaaa ggctctttgt caactgtagt gggttgaaaa
     1201 aaactggctc tttgtcaact gtagtgggtt gaaaaaaaac taagctcgag aaaggacaaa
     1261 ttttgtcctt tcttttttga tattcagagc gataaaaatc cgttttttga agttttcaaa
     1321 gttccgaaaa ccaaaggcat tgcgcttgat aagtttgatg agattattgg tcacttccaa
     1381 tttggcgttt gaatagggta gttgaagggc gttgacgatt ttctctttgt cctttagaaa
     1441 ggttttaaag acagtctgaa aaataggatg aacctgctta agattatcct caataagtcc
     1501 gaaaaatttc tctggttcct tattctgaaa gtgaaacagc aagagttgat agagctgata
     1561 gtgatatttc aagtcttgtg aatagctcaa aagcttgtct aaaatctctt tattggttaa
     1621 atgcatacga aaagtaggac gataaaatcg cttatcactc agtttaaggc tatcctgttg
     1681 tatgagcttc cagtagcgct tgatagcctt gtattcatgg gattttcgat gaaactgatt
     1741 catgatttga acacgcatac gactcatagc acggctaaga tgttgtacaa tgtgaaagcg
     1801 atccaacacg attttagcac acgggaaaag ttgtctagct aagtcatagt aagggataaa
     1861 catatccata gtaatgattt tgacgcgaca taggacagct ctatcgtagc gaagaaagtg
     1921 atttcgaatg atagcttgtg ttct
//
LOCUS       DAVDHZ010000090         1921 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000090 DAVDHZ010000000
VERSION     DAVDHZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.092"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            112..1845
                     /locus_tag="VUR46_002150"
     CDS             112..1845
                     /locus_tag="VUR46_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010051926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HET5457489.1"
                     /translation="MRVKQSKSKNTINYAIIKDIKVGNKRTSTIVENLGNHNTLLKEH
                     PDMEPLEWARLRAKELTEKEKEENKDFLITFSQNKQLKQNQLNEYHGGYLFLQDLYHQ
                     LDLPRINKEIQKRHRFNFSLDDILSRLIYGRILAPASKRSTLEFSKTLLEPKEFELQH
                     FYRALEVISNETEFIQEQTYQTSKKMTQRQTEVLYYDCTNFYFEIEAEDEEGLLRQYG
                     PSKEHRPNPIVEMGLFMDKQGIPLAFCIHPGNTNEQTTLKPLERKIVKEYKASKFVVC
                     TDAGLSSKANKMYNSFGERSYVTTQSIKKLKKEYRDWALDKSGWRMVGDKNPIFYNLD
                     ELEHREELKKQLFFKESPFYDEDLPNQRLIVTFSTKYQDYHRTIRERQIERASKLLGK
                     PSQATKKRQTDFKRFLKETSTTKEGEIAEKRILTLDEERIQEEAQYDGLYAVATNLDE
                     DIQTIVVINQRRWEIEESFRIMKQELRARPVYLSRSDRIQAHFTICFLALMIYRLLEK
                     QLGETVTCSELIQTLRNYKFKHLYGAGYLPTYTRTTITDQLHQAFGFQTDFEIISEKN
                     MKKIFKKTKSR"
BASE COUNT          704 a          362 c          341 g          514 t
ORIGIN      
        1 gtgaaaaact cctcataaag gttgatataa ggggattttc ttgtcaaatt tcaccgtttt
       61 ttatttgcgt acttttccgt actttgttat aatagagcga ggtataaaaa gatgagagtg
      121 aaacaatcaa agtcaaaaaa cactatcaac tacgctatta ttaaagacat caaggttgga
      181 aataaacgga cttctactat cgtagaaaac ttaggcaatc ataacacact cttaaaagaa
      241 catcctgata tggaacctct tgagtgggct cgtttacgtg ccaaggaatt aactgagaaa
      301 gaaaaagaag aaaataaaga tttcctcatt acctttagtc agaacaaaca gttaaaacaa
      361 aatcaattga acgaatatca tggaggctat ctcttcctac aagacctcta tcatcaacta
      421 gatttgccta gaattaacaa agaaatccaa aaacgacatc gttttaattt ctctctagat
      481 gatatcctat ctcgattgat ttatggacgg attctagctc ctgcttcaaa acgatccacc
      541 ctagaatttt caaaaacatt actcgaacct aaagaatttg aactccaaca tttttatcgg
      601 gctcttgaag ttatttctaa tgaaacagag tttatacaag aacaaaccta tcaaacttca
      661 aaaaagatga cccaacgaca gacagaagtt ctctactatg actgtactaa cttctatttt
      721 gaaattgaag ctgaagatga ggaaggactt ctgagacaat acggtccatc taaagaacat
      781 cgcccaaatc caattgtgga gatgggactc tttatggaca aacaaggaat tcccctagct
      841 ttctgtatcc accctggaaa tacaaatgaa caaactactc ttaaaccatt agaaagaaag
      901 attgtcaagg agtacaaggc ttcaaaattt gtagtctgta cagatgctgg actctcatca
      961 aaagccaata agatgtacaa ttcttttggg gaacgttcct atgtcacaac tcaatctatc
     1021 aagaagttaa agaaagaata cagagactgg gctttggata aaagtggttg gcgaatggtt
     1081 ggggataaga atcctatctt ttacaatctg gatgagctag agcacagaga ggaattaaaa
     1141 aaacagctct tctttaaaga atctcctttt tatgatgaag atttaccaaa tcaacgcttg
     1201 attgtgacct tttctactaa atatcaagac tatcatcgaa cgatacgaga gagacagatt
     1261 gaacgggcta gtaagttact gggcaagccc agccaagcta ccaagaagag acaaaccgat
     1321 tttaagagat ttctgaaaga aacaagtact accaaagaag gggaaatcgc cgagaaaagg
     1381 attctaactc ttgatgagga acggattcaa gaagaggctc aatatgatgg tctctacgcc
     1441 gtagccacta atctagatga agatatccag acaattgtag tcatcaatca aaggcggtgg
     1501 gaaattgaag agagttttcg tatcatgaag caggaactac gagccagacc cgtttatctc
     1561 agccgttcag ataggattca agcacatttc actatttgtt tcctagcact aatgatttat
     1621 cgtctcttgg aaaaacaact aggagaaaca gtcacctgtt cagaactcat ccaaacctta
     1681 cgcaattaca agttcaaaca tctttatgga gcaggatatc ttccaactta caccagaaca
     1741 actatcacgg atcaactcca ccaagcattt ggtttccaaa ctgattttga gattataagc
     1801 gaaaaaaata tgaaaaaaat ttttaagaaa accaaatcta gataaaaagt acgcattttt
     1861 taaaaagaga aaaagagctc cgaaaagctg tcatatcagt atttaggggc tctttgattt
     1921 c
//
LOCUS       DAVDHZ010000091         1884 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000091 DAVDHZ010000000
VERSION     DAVDHZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.093"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            120..>1884
                     /locus_tag="VUR46_002151"
     CDS             120..>1884
                     /locus_tag="VUR46_002151"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET5457490.1"
                     /translation="MNKKKMILTSLASAAVLGAGFVASQPFVVNAYDNTSTTEEGRNQ
                     ENALADASEKEYKKLADEKAKKDLFDGLDKVEKELIDKVNQSQKLSEEKDKLISKIKA
                     EIESQKNDIKSALEAGLSVDEVLANLPQDGDEGTSTASSQDSPVNKTIEPEVEAKIKE
                     IEEKEANRPLSEKFQDIADDLNGKIEKLKEKAEKAKQDVEAKLDIKKAAEVTLEKAKS
                     HLKSVKKDNTINDVNKQNVERLIAEAQAVVDASQKALTQATLAAEESYTQLGGIVVEI
                     NALTDTYNESVAKAEENKKLEEAAENEKKAEELQTKVVDLEREVITAQNEVDNLKKVL
                     AGLDPDDDTEAIEAKLKEGEAKLSTKQAELAKKQTELEKLLDSLDPEGKTQDELDKEA
                     ELDNKVDALQSKVADLEKEVFDTQTKVDKLKTRLAGLEPENSSSVEDELAEAEKTLAE
                     KQSELEKTQKELDAALNELGPDGDEPTQPEKPAEEPTRPAPAPEAPAEQPKPEKSAEQ
                     QAEEDYARRSEEEYNRLTQQQPPKAEKPAEEPTQPAPAPEQPTEPTQPEKPVAPKTGW
                     KQENGMWYFYNTDGSMATGWLQ"
BASE COUNT          803 a          304 c          369 g          408 t
ORIGIN      
        1 aagcttatga tatagaaatt tgtaacaaaa atgtaatata aaacacttga caaatattta
       61 cggggggata taattaatat atagtctgaa aaggattatc agaaaagagg taaatttaga
      121 tgaataagaa aaaaatgatt ttaacaagtc tagccagtgc cgcggtctta ggggctggtt
      181 ttgttgcatc tcagccgttt gttgtaaatg catatgacaa tacttctaca actgaagagg
      241 gtcgaaatca ggaaaatgct ttagctgatg cgtctgaaaa agaatataag aaattagcag
      301 atgaaaaagc taaaaaagac ttgtttgatg gattagataa agttgagaaa gaactcattg
      361 ataaggttaa tcaaagccaa aaactctcag aagaaaaaga taaacttatt agcaagataa
      421 aagcagagat tgaatcacaa aaaaatgata tcaagagtgc tttagaggct ggactgtctg
      481 ttgatgaagt tttagctaat ctacctcaag atggtgatga aggaacatct acggcatctt
      541 cacaagatag tccagtaaat aaaactatcg aacctgaagt tgaagcgaaa attaaagaga
      601 ttgaggaaaa agaagctaat cgtccactat ctgaaaaatt ccaagatatc gcagatgact
      661 taaatggaaa aattgaaaaa ttaaaagaaa aagctgagaa agctaaacaa gatgtagaag
      721 ctaaattaga catcaaaaaa gctgccgaag taacgctaga aaaagctaaa tcacacttaa
      781 aatctgttaa aaaagataat actatcaatg atgttaacaa acaaaatgta gagagactga
      841 ttgcagaagc tcaagctgta gtagatgcta gtcaaaaagc tttaacacaa gctactctag
      901 ctgctgagga atcgtatacg caattaggtg gaattgttgt tgaaatcaat gctttaacag
      961 atacttataa tgaatcagta gcaaaagcag aagaaaataa aaagcttgaa gaagctgcag
     1021 aaaatgagaa aaaagcagaa gaacttcaaa ccaaagttgt tgatttagaa agagaagtta
     1081 ttacagctca aaatgaagta gacaacttga aaaaagttct tgctggtctt gatcctgatg
     1141 atgacacaga agctatagaa gctaaattaa aagaaggaga agctaagcta agcactaaac
     1201 aagctgagtt agcaaaaaaa caaacagaac ttgaaaaact tcttgacagt ctagatcctg
     1261 aaggtaaaac tcaagatgaa ttagataaag aagctgaatt agataacaaa gttgatgccc
     1321 ttcaaagcaa agttgctgat ttagaaaaag aagtttttga cactcaaacg aaagtagata
     1381 aactaaaaac acgtcttgct ggtcttgaac ctgagaactc atcttcagta gaagacgaac
     1441 tagcagaagc tgaaaaaaca ttagctgaaa aacaatcaga attagaaaaa actcaaaaag
     1501 aattagatgc agctcttaat gaattaggac cagatggaga tgagccaact caaccagaaa
     1561 aaccagctga agagccaact cgaccagcac cagccccaga agcaccagct gaacaaccaa
     1621 aaccagagaa gtcagcagaa caacaagctg aagaagacta tgctcgtaga tcagaagaag
     1681 aatataaccg cttgactcaa cagcaaccgc caaaagctga aaaaccagct gaagagccaa
     1741 ctcaaccagc accagcccca gagcaaccaa ctgagccaac tcaaccagaa aaaccagtcg
     1801 ctccaaaaac aggttggaaa caagaaaatg gtatgtggta cttctacaat actgatggtt
     1861 caatggcgac aggatggcta caaa
//
LOCUS       DAVDHZ010000092         1665 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000092 DAVDHZ010000000
VERSION     DAVDHZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.094"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..735)
                     /locus_tag="VUR46_002152"
     CDS             complement(<1..735)
                     /locus_tag="VUR46_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5457491.1"
                     /translation="MHIHHNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEDCHFHAF
                     YHAFGRPSYHPKMLVSALLFAYSQGIFSGRKIEKMMIENLAMQYLTGQLVVSYRTINR
                     FRVAGGMEELIRNLFIDLNLRLKMEEFVTLDCLFIDGTKIEANANKYSFVWKKATDKF
                     AAKLQEQIQVYFQEEITPLIHQAIKLEEEEPISSEQLLAFAQVLEEELEKLNQNIEET
                     AIKGKDERKNQRRKLKKVLRIVKEDFS"
     gene            1045..1155
                     /locus_tag="VUR46_002153"
     CDS             1045..1155
                     /locus_tag="VUR46_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET5457492.1"
                     /translation="MRARHERRNRYSIRKFSVGVASVVVATFFCAGGGDK"
     gene            1221..>1665
                     /locus_tag="VUR46_002154"
     CDS             1221..>1665
                     /locus_tag="VUR46_002154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457493.1"
                     /translation="MHDLLGRLSLTEGEKEKYRNQIDTATELDKLVELEGTLDNLQNK
                     EIEEAVEKAKVTLPQYMDTRLKELDQTGSGFPDLLKKLQNIIDEYREQLDGLPNKKAV
                     EDLVEQAKEEMDGYIAEYQKTLTAGQDDNNGAGEQAPQAGDNNGAG"
BASE COUNT          534 a          299 c          366 g          466 t
ORIGIN      
        1 tgaaaaatcc tccttgacta tacgcaagac tttcttgagt ttccgacgtt ggtttttacg
       61 ttcatccttc cctttaatag ctgtctcctc aatgttctgg ttcagttttt ccaattcttc
      121 ttcaaggact tgagcgaatg caagcaactg ctccgaggag ataggctctt cttcctccaa
      181 cttaatggcc tgatggataa ggggagtgat ttcttcttga aaatagactt gtatctgttc
      241 ttgaagtttg gcggcaaact tgtccgttgc tttcttccac acgaaactat acttattggc
      301 attagcttca atcttagtcc cgtcaataaa caagcaatct aaggtcacga actcttccat
      361 ttttaaacga agattgaggt cgatgaaaag attgcgaatg agttcttcca tccctccagc
      421 tacacgaaaa cgattgatgg tgcgatagct gacaaccaac tgccctgtta ggtattgcat
      481 agccagattt tcaatcatca ttttttcaat ttttcgtcca gagaaaatcc cttgtgaata
      541 ggcaaataga agagcagata caagcatttt agggtgataa gacgggcgac caaaggcatg
      601 atagaaggcg tggaaatgac aatcctccaa ggtattcacc actttttcaa tagtgaagac
      661 gagatggtct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
      721 atggtgaata tgcatgggat agcctttcta aatggtttat tgtgcaattc tattttacca
      781 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcttttttt ggagataaga
      841 gacttttgtc ccagactcct tgagtgaaac caaaggaatg aatcataatt atgaatctag
      901 taaagcattc tccgagagcc attttaaagg tcgagttgga attaaacaag aagaaactat
      961 ctaaagcaaa gtctgattca tatttattta acatttgtag gatagactag taaaaaaata
     1021 aaaatatatt ggaggaactt actcatgaga gcaagacatg aacgacggaa ccgatattct
     1081 attcggaaat ttagtgtagg ggtagccagt gtagtggttg cgaccttctt ctgcgccggg
     1141 gggggggaca agtagtccag gctgctgatg gagcgagacc tcaaggagta tcctcaacct
     1201 tagatagcta tagaaagacc ttgcatgatc tgttaggaag gttatcttta actgaaggag
     1261 aaaaagagaa atatagaaac caaattgata ctgcgacaga gcttgataaa ttggttgaat
     1321 tagagggcac tttggataat cttcagaata aagaaattga ggaagctgta gaaaaagcga
     1381 aagtaacttt gccccagtat atggatactc gtttaaagga acttgatcaa acaggttctg
     1441 gttttccaga ccttctgaaa aagcttcaaa acattataga tgagtatcgt gaacaacttg
     1501 atggccttcc aaataaaaaa gcagtggaag acttggtaga acaagccaaa gaggaaatgg
     1561 atggttatat tgctgaatat caaaaaacat taactgctgg ccaagacgac aacaacggag
     1621 ctggtgaaca agcacctcaa gcaggcgaca acaatggagc tggtg
//
LOCUS       DAVDHZ010000093         1614 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000093 DAVDHZ010000000
VERSION     DAVDHZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.095"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            150..526
                     /locus_tag="VUR46_002155"
                     /pseudo
     CDS             150..526
                     /locus_tag="VUR46_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810398.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            691..990
                     /locus_tag="VUR46_002156"
     CDS             691..990
                     /locus_tag="VUR46_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET5457494.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1251..1591
                     /gene="tnpB"
                     /locus_tag="VUR46_002157"
                     /pseudo
     CDS             1251..1591
                     /gene="tnpB"
                     /locus_tag="VUR46_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          553 a          315 c          288 g          458 t
ORIGIN      
        1 aagattatac cacattgtgt actatttttg gttcatttta ctataataat aacgatacta
       61 gataatgagg aaaatgcaat ggcaaaccca actttcggag aaaaaaagcg aatacagact
      121 atattgctcg ctatggcgta tatgcagtta tccctaatcc tgaacaaaaa caaattgttc
      181 ttgttcaaca accaaatggt gcttggttcc taccatgtgg agaaattgaa gcaggtgaaa
      241 atcatcagga agccctaaag cgtgagttga ttgaagagct tggtttcaca gcagaaattg
      301 gtacctatta cggacaagtt gacgaatatt tctattctcg tcatcgtgat acctactact
      361 acaatcctgc ctacctctat gaagcaactc ctttcaaaga agtacaaaag ccactagaaa
      421 actttaatca tattgcctgg ttcccgacga ggctatccaa aaccttaaac gtggtagcca
      481 taaatgggcc attgaatctt ggaaaaaaca gcataagatt ggctaatact cttcgaaaat
      541 aaaattcaaa ccacgtcagc gtcgccttac cgtactcaag tataggctgc ggctagcttc
      601 ctagtttgct ctttgatttt cattgagtat aaatcaagcg actttattca aaaagtgcta
      661 taatagaatt agaaaatcgg aggaaatatt atgaagctta tcaatacgac aaactcacac
      721 tcgcaacttg taaaaagtca gctagaaagt accgatgcaa cccttgttga ggtttattct
      781 gcagggaata cagatgttat ttttacccaa gctccgcttc actatgaaat cctcatctca
      841 aacaaacacc gtgctattcg tgagcctgaa atcgaaacca ttcaagaatt tttcttgaaa
      901 cgtaaaattg ataaggcctc tgttgatgaa gccaatatca agacactcta ctcagagaaa
      961 ttaattggaa tttcaatccc aatcaagtaa gaaaattgag taaaaactcg atttgagaga
     1021 aagtccaata agtctttcca taataaaacg catagtagca agagtttcta cacccactat
     1081 tatgcgtttt tatcattttg aaatctactg ctaatcaatg aagaagcaaa gatcaaacta
     1141 ggcagctagt tacaagttac gtaagcgcgt cataacaagg tatctatcct aattccccaa
     1201 cttccagtat actagataaa aaataattat cagaggaaaa gtattgtact atgatgattc
     1261 tactaagtga tttaggtcaa gttcaccttg tttgtggcaa gacagatatg aggcagggaa
     1321 tagactcatt agcctatgta gttaaaaccc actttgaatt ggatcctttc tccggtcaag
     1381 tctttctctt ttgtggtgga cgtaaagacc gctttaaagc cctttactgg gatggtcaag
     1441 gattttggct actatataaa cgctttgaga acggaaaact gacttgacca agtacagaaa
     1501 aggatgtcaa agctctcaca ccagaacaag tagactggct tatgaagggc ttttctatca
     1561 ctccaaaaat aaatccatca gaaagtcgtg atttctattg aaatgaggac tttc
//
LOCUS       DAVDHZ010000094         1425 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000094 DAVDHZ010000000
VERSION     DAVDHZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.096"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..1287
                     /locus_tag="VUR46_002158"
     CDS             <1..1287
                     /locus_tag="VUR46_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5457495.1"
                     /translation="SSGDLIYSINGLGRIRQLFTNQVVLGILDIGFVICILFYFLYID
                     FFVTIIALMLVVINLLLLLLTRKNLEQKSKSFVIAQNDLQNKQIEMIYSMMGIKMEGF
                     EVRTFKQWKGYLDKYLYRYRASELFSSVVNSLFSIITFISPFILLFIMLLPDNHLGNK
                     LGGIFAVYSLSSLLFGKINSIFDTIVAFYNSKTFLSRILEILGEETEINGVVKHDLNG
                     EIALKNVSFSYTRDSKKVLSNVSIEIKKGEKVAIVGSSGSGKSTLSKLLIGLFPASSG
                     SILFDDLDYNLLDKQYLRQQIGIVPQDMTLFNKTIHENIAGDISVSEEEMTKICKLVN
                     IHDEIMEMPMGYNTLVSEMGMNLSGGQRQRIILARALVKKPKIILLDEATSYLDNVNE
                     NEIMQKFKEQNITIIVIAHRLSTIIDSNQIFVMDKV"
BASE COUNT          491 a          176 c          258 g          500 t
ORIGIN      
        1 agtagtggtg atttaattta ttctataaat ggtttgggta gaattcggca attatttaca
       61 aatcaggttg tactaggaat attagatatt ggttttgtaa tttgtatttt gttttacttt
      121 ctatatattg attttttcgt gacgattatc gctcttatgt tagtggtaat aaatttgttg
      181 ttgcttctat tgactagaaa gaatttggaa caaaaaagta aatcttttgt gatagctcag
      241 aatgatctcc aaaataaaca aatcgaaatg atttattcta tgatgggaat aaaaatggaa
      301 ggatttgaag ttcgaacgtt taaacaatgg aaaggttatt tagataagta tctttataga
      361 tatagagcca gtgaattgtt ctcaagtgtt gttaattcgt tattttcaat tatcactttt
      421 atatctccat ttatcctatt atttattatg ttgttgccag ataatcattt aggtaataag
      481 ttaggtggaa tttttgcagt atattcttta tcatctctat tatttggtaa gattaatagt
      541 atttttgata cgattgtagc attctacaat agcaaaacat ttttatctcg gattttagag
      601 attttaggtg aagaaactga aataaatggt gtagtgaaac acgacttaaa tggggaaatc
      661 gcacttaaaa atgtttcatt ttcatatact agagatagta aaaaagtact ctctaatgtg
      721 tctattgaaa taaagaaggg ggaaaaggta gcaattgttg gctcttctgg atcaggtaaa
      781 agtacccttt ccaaattatt gataggttta tttccagcat cctcaggtag tattttattt
      841 gatgacttag attataattt gttggataaa cagtatcttc gtcaacaaat tggcattgtc
      901 ccacaagaca tgactttatt taataaaacc atacatgaga atattgctgg agacatctca
      961 gtctcagagg aagaaatgac aaaaatttgt aagttagtta atatccatga tgaaattatg
     1021 gaaatgccca tggggtataa tactttagtt tcagaaatgg gaatgaatct gtcaggaggg
     1081 caacgtcaga gaattatttt agcaagagcg ctagttaaga aacctaaaat aatactttta
     1141 gatgaagcca caagttatct agataatgtt aatgaaaacg agattatgca gaaatttaaa
     1201 gaacaaaata tcacaattat tgttattgca catcgacttt ctaccattat cgattctaac
     1261 cagatttttg taatggataa agtctagtgg taaaatgtca agcgaccccc cgctcaaagt
     1321 ttgaaaacta tttcaaaaaa agggtgcact aaagaagccc tactgaaaac gatgttttca
     1381 aactgttttc agtagatttt caaggagagg tgcagatata actta
//
LOCUS       DAVDHZ010000095         1397 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000095 DAVDHZ010000000
VERSION     DAVDHZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.097"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            244..>1397
                     /locus_tag="VUR46_002159"
     CDS             244..>1397
                     /locus_tag="VUR46_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017271.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET5457496.1"
                     /translation="MKKSYRDDNGEKVFRYSIRKYHFGAASVAVAALMFFANGAVAAS
                     ETITPTTASDVVKAGSDGNADGNPASSDEGDSKQALTDKPAELKAADELKTQEAPAEG
                     ANQTSSTGILQPRTLKNNQSDYDPIPIEDDEDDVRDGLFSSENPVTTIQPRSSHSVTG
                     RALQGDTQAPKVSLGSALLPTSKSTATTPLYRIRQGQAFTPKLKVWNNSGSIKSLDIT
                     GIPNGVTKHRFGTDFSEQTAATEMNPYSGSTLSGNVPDTQAVGQHIAQITVKDASNNV
                     ATYYLKYEVYPARVEAKQGRFGQVKDKALIHGDDPANYIKFKSANGKEVQKPADVKVT
                     WERKPSTVEAGLNKTGLVKVTYHVTDENGVVRDEVQTVTINTPVYHATLV"
BASE COUNT          476 a          277 c          312 g          332 t
ORIGIN      
        1 aaaatgacaa gtattttgat aataacttgc caacatctat cacttatcgg aatgttaaaa
       61 aagttagcgt tttgctgttc aaatttgcga aaatagtata taatagtact gtctcaaaac
      121 ttgtcttttg acaagcctgg gaacaaaaag aaaaaaacat atcctttcct taaatactaa
      181 aatatttagg gggggggtat tttttagtac ctccagaaag gaaaaacgag aggtaattca
      241 atcatgaaaa aatcatatcg tgatgataac ggggaaaagg tcttccgtta ttccattcgt
      301 aagtaccact ttggtgctgc cagtgttgcg gtagcggctc tgatgttttt tgccaacgga
      361 gctgtggcag cgagtgaaac gattactcca actacggcaa gtgatgtcgt taaggcaggt
      421 tctgatggca atgcagatgg aaatccagcg tcctcggatg agggagactc caagcaagct
      481 ctgactgaca aaccagctga actcaaagca gctgatgagc tgaaaacgca agaagcgcca
      541 gctgagggag ccaatcaaac aagtagtact ggaatcctcc agccgcggac gctcaaaaac
      601 aatcagtctg actacgaccc tattccaatt gaggatgatg aggatgacgt aagagatggg
      661 ctgttttctt cggaaaatcc agtaaccact atccaaccac ggagctctca ctctgtaacc
      721 ggtcgcgcac ttcaaggcga cacacaagcg ccaaaagtga gtttgggcag tgctcttctt
      781 ccgactagca aaagtacggc tactacgcca ttgtacagaa tccggcaagg gcaagctttt
      841 acaccgaaat taaaagtttg gaataactcg ggatctatca aaagcttaga tataacggga
      901 ataccgaatg gagtgaccaa gcatagattt ggaactgact tttcagaaca gacggcagct
      961 actgaaatga atccctacag tgggtcaaca cttagtggta atgtgccaga tacacaagca
     1021 gtaggacaac atatagctca aattactgta aaagatgcat cgaataatgt agctacttac
     1081 tacctaaaat atgaagtcta tccagcaaga gtagaagcta agcaaggtcg atttggacaa
     1141 gtcaaagata aagccttgat acatggcgat gatccagcta actatatcaa gtttaaaagc
     1201 gctaatggaa aagaggttca aaaaccagca gatgtaaagg tgacgtggga acgtaagcca
     1261 agtacagtag aagcaggtct taataaaaca ggactagtaa aggttaccta ccatgtaaca
     1321 gatgaaaatg gtgtggttcg agatgaagtt caaactgtaa caatcaatac ccctgtctat
     1381 catgcaactc ttgtaca
//
LOCUS       DAVDHZ010000096         1181 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000096 DAVDHZ010000000
VERSION     DAVDHZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.098"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            154..1047
                     /locus_tag="VUR46_002160"
     CDS             154..1047
                     /locus_tag="VUR46_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HET5457497.1"
                     /translation="MYITAKEAAKKWGISDRRVRILCSEGKIHGAYQEGRNWKIPCDA
                     VKPTDGRYKTKESLILVLGDKLETLKKRRPLTEGEVERLNEEFLVEYTYNSNAIEGNT
                     LTLRETDMVLRGLTIDRKSLKEHLEVIGHKDAFDYVRQLVRENAPISEKIIKDIHYLV
                     LADKKEDRGVYRRVPVRIMGAAHEPVQPYLIVPKMEELLERYENSKEDIVTRLARFHI
                     EFESIHPFIDGNGRTGRLLVNLELMKAGYPPIDIKFTDRLKYYEAFDHYHLKDDLSAM
                     ADMFALYLNQKLDLYLSILDK"
BASE COUNT          418 a          166 c          243 g          354 t
ORIGIN      
        1 cctaatcaat ttgttcacat ttaccttcga tatattatat cccatagtta tagtggaaaa
       61 cactattgtt cggataaatg gtagatgtta ttccgactcc cttgctattg ttccgacaag
      121 gtgatataat gtgacagaac ggagggataa aaaatgtata ttacagcgaa agaggccgct
      181 aaaaagtggg ggatatctga cagaagggta agaattttgt gctcagaagg gaagattcac
      241 ggtgcatatc aagagggaag gaattggaaa ataccatgtg acgcagtaaa gccgacagat
      301 gggagatata agactaaaga atcactcatt ctagtcttgg gagataagtt agaaactcta
      361 aaaaaacgac gtcctttaac tgaaggagaa gtggaaagat taaatgaaga atttttagta
      421 gaatatacat acaattctaa tgctattgaa ggaaatacac tgactttacg tgaaacagac
      481 atggttctta gaggacttac aattgaccga aaatccttaa aagagcattt ggaggtcatt
      541 ggacataaag atgcttttga ttatgtaagg caacttgttc gtgaaaatgc tccaatatct
      601 gaaaaaatta taaaagatat tcactatttg gttttggcag acaagaaaga agatagaggt
      661 gtgtatcgaa gagttccagt tcgaattatg ggagcggctc atgaacctgt gcaaccctat
      721 ttaattgttc ctaagatgga agagttactg gaacgatatg aaaatagcaa agaagatatt
      781 gttactagac ttgcccgttt tcatattgag ttcgaatcta ttcatccctt cattgatgga
      841 aatggaagaa cagggaggtt gttggttaat ttggaactga tgaaagcagg ttatccacct
      901 attgatataa aatttactga tagattaaaa tattatgaag cttttgacca ctatcattta
      961 aaggatgatt tatcagccat ggcagatatg tttgctctat atttgaatca gaaactagat
     1021 ttatatttat ctattttaga taaatgagaa taaaagaatt ccgtagaact tcaaattttt
     1081 gtcaatagag ctcttttaag ataatctaat ctatagacta ggctggttcg gtatctttct
     1141 gaaaaaatcc ttaacaaacg ccagcaaaaa gttagcgttt t
//
LOCUS       DAVDHZ010000097          881 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000097 DAVDHZ010000000
VERSION     DAVDHZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.099"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            133..881
                     /locus_tag="VUR46_002161"
                     /pseudo
     CDS             133..881
                     /locus_tag="VUR46_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element ISSpn10 family transposase"
BASE COUNT          283 a          189 c          166 g          243 t
ORIGIN      
        1 gtaggatgca ggcggctctg tcaggctgtg ataaggattc tcttatgcga ggatgttgga
       61 acaaggtgtt tctgggaaac cttacagtag tcaaaaaaac ttccaaatct aatggaaagg
      121 agaccttcct taatgaaatg ttttgtcggt ttagacgtca gctctacaaa attagatgtg
      181 tgtatcatgt tgagtgatac tagcaccccc gtcactgctt ccctctctaa tgacctttct
      241 ggggcaacag agattaagaa tcatatcctt gatttgaatc atacctatca cttcgaaagg
      301 attgtcattg gcatggaagc aaccagtctc tacagtttcc accctgctat gttcttccat
      361 gaagatagtc agttgaaaga actacatgtt gagattatgg tcgaacaacc taataaaatc
      421 aagaaatatc gggatgcttt cgaagaaaac aaaaacgata ccattgatgc tttctacatt
      481 gcggattatt tccgtattga gcgattttca ccttctttct taaaagaaga gaaatacatg
      541 gctctccaac atctcacaag aaccagactc caaatcatcg agcaattaac cagaaccaaa
      601 cagcacttca ttgaaaatat ctactacaag tgcaatacct tggcttagca attcaagaaa
      661 gaagaactct ctactaacct atggagttca acgatgatga ccttgataac agatgagatg
      721 accttagacg aacttgctaa catgcctctt caagaattag ctgattggct ccaacaactg
      781 ggtaaagggc attttaagga ctctgagaag cttgctcaaa ccattcaagc cgctatcaga
      841 ggttcttatc gcctctctaa actccaacaa gattcagtca a
//
LOCUS       DAVDHZ010000098          844 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000098 DAVDHZ010000000
VERSION     DAVDHZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.100"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..469
                     /locus_tag="VUR46_002162"
     CDS             <1..469
                     /locus_tag="VUR46_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5457498.1"
                     /translation="KNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTELID
                     IICQKFNVSYVDIVGEDKMFNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGISID
                     DESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            469..>844
                     /locus_tag="VUR46_002163"
     CDS             469..>844
                     /locus_tag="VUR46_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET5457499.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPK"
BASE COUNT          300 a          113 c          175 g          256 t
ORIGIN      
        1 aaagaacata aaatccttac gtaaaacaca tgacttaaca caacccgaat ttgcacgaat
       61 tataggaatt tctcgaaata gcttgagtcg ttatgaaaat ggaactagtt cagtctctac
      121 ggaactaata gatatcattt gtcagaagtt taatgtatct tatgtcgata ttgtaggaga
      181 agataaaatg ttcaatcctg ttgaagatta tgaattgact ttgaaaattg aaattgtgaa
      241 agaaagaggt gctaatctat tatctcgact ctatcgttat caagatagtc agggaattag
      301 cattgatgat gaatctaatc cttggatttt aatgagtgat gatctatctg acttgattca
      361 tacgaatatc tatttagtag aaacttttga tgaaatagag agatatagtg gctatttgga
      421 tggaattgaa cgtatgttag agatatctga aaagcggatg gtagcttaat ggaaatccaa
      481 gattatactg atagtgaatt caaacatgct ttagcaagga atcttcgttc actgacaaga
      541 ggaaaaaagt ccagtaagca acctatagcg attttgcttg gagggcaaag tggtgctggt
      601 aagactacaa ttcatcgtat taaacagaaa gaatttcaag gaaatattgt tatcatagat
      661 ggtgatagtt ttcgttctca gcatccacac tatttagaac tgcagcaaga atatggcaaa
      721 gatagcgttg aatacaccaa agattttgca ggaaaaatgg tagagtcttt agtaacaaaa
      781 ttgagtagtt tgggatacaa tcttttgatc gagggaactt tacgaacgat tgacgttcca
      841 aagg
//
LOCUS       DAVDHZ010000099          831 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000099 DAVDHZ010000000
VERSION     DAVDHZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.101"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..629
                     /locus_tag="VUR46_002164"
     CDS             <1..629
                     /locus_tag="VUR46_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457500.1"
                     /translation="SVGFVGNSQTGTTPSAVDKSELQSLVEDLERRLQDLADLSPEAL
                     EEAQSILREAQVALANDSLTAQELTELLAKVRQALNSIQAGTSADKSPSTSNSNKEAE
                     SAKEPTNATDVPLYGVFGAAVLSLLGALLFAVARKKNSQLDKLSRELDQLLVELEASD
                     KDKKGLGKAKKLAKKARTFVDSQQKDPQKEAELISEIKTILSQLREGV"
BASE COUNT          267 a          159 c          190 g          215 t
ORIGIN      
        1 gaagtgtagg atttgtaggg aattcccaaa caggtacaac tccatcggct gtggacaagt
       61 cagagcttca gtctctggta gaggacctgg agcgtcgcct acaagattta gcagatttat
      121 ctcctgaagc acttgaggaa gcacagagta tcttgagaga ggcgcaagtg gctcttgcta
      181 atgactcctt aacagctcaa gaattaacgg aactccttgc caaagttaga caggctctta
      241 attctataca agctggcaca tcagctgata agagtccgtc tacgtcaaac tcaaataagg
      301 aagcagaaag cgccaaggaa cctacaaatg cgacagatgt ccctctatat ggtgtctttg
      361 gagctgcagt actctctctt ctaggagctc tcctctttgc agtggctcgt aagaaaaact
      421 ctcaactaga taagctttca agagaattgg atcaacttct agttgagtta gaggctagtg
      481 acaaggataa aaaaggttta ggcaaggcta aaaaattagc taagaaagca agaacctttg
      541 tggatagcca gcaaaaagat cctcaaaaag aagcagaact aatttctgaa atcaagacta
      601 ttcttagtca actcagagaa ggagtctagt cttgaagaaa acttactttc aaaaacgaag
      661 tgagtaggtt tgtagcgatg atgaggaaat aaaaaatctc cagattagga accatcagtg
      721 agttctctag tctggagatt tttcggctct ttgtcaactg tagtgggttg aagtcagcta
      781 agctcgagaa aggacaaatt tcgtcctttc ttttttgatg ttcagagcga t
//
LOCUS       DAVDHZ010000100          827 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000100 DAVDHZ010000000
VERSION     DAVDHZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.102"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>827
                     /locus_tag="VUR46_002165"
     CDS             <1..>827
                     /locus_tag="VUR46_002165"
                     /inference="COORDINATES: protein motif:HMM:NF020018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457501.1"
                     /translation="PIIRSNSDTLLSTAVEDAVTVTNKENVEKQGNLPTGIGKHTINA
                     KVTYKDQSEEMVEIPYTIKPDAPSISTSIGTAGKNSVTVNNVTPGTTVVVYDMTNPNN
                     PIELGRKDVSGATADAAQNGVTVSTNATLRKDTPIAAEVIYKPTVAAERISSDKSSSL
                     VVKEGLAVNSIHAVKGENYTGDLASRIHYNDGQDTGLPAGSTVEWKNNQAPDYNNVGT
                     SRYTLVVNVPNQGTTEIEVPVHVYPTASLKKASYTNKQGTLSNGTDASKYVQFEGSA"
BASE COUNT          302 a          176 c          183 g          166 t
ORIGIN      
        1 cgccaatcat tcgctcaaac agcgacacgc ttctctcaac agcagtagaa gatgcagtaa
       61 ctgtaaccaa taaagagaat gttgaaaaac aaggaaacct tccaaccgga attggaaaac
      121 ataccatcaa tgccaaggtt acttacaaag accaaagcga agaaatggta gagattccat
      181 atactatcaa accagatgcg ccaagcatta gcacaagtat cggtacagcg ggcaaaaata
      241 gtgtgacggt taataatgtg actccaggca cgacagtagt agtgtatgac atgacaaacc
      301 caaacaaccc gattgaattg ggacgcaagg atgtgtcagg tgctacagca gatgcagcgc
      361 aaaatggagt gacggtttca accaatgcga ctctaagaaa agatactcca atcgcagccg
      421 aagtgattta caaaccaaca gttgcggcag agcgtatcag ttcagacaag agcagtagct
      481 tggtagtcaa agaaggtttg gcagtcaaca gcattcatgc ggttaaagga gaaaactata
      541 caggtgacct agcttctcgt atccactata acgatggaca agacacaggt cttccagctg
      601 gttcaactgt tgaatggaag aacaaccaag cgccggacta caacaatgta ggaacaagtc
      661 gttatacact tgtagtaaac gttccaaatc aaggaactac agaaatagaa gtaccagtcc
      721 atgtttaccc aacagcaagc ttgaagaagg ctagctacac caataaacaa ggtactctgt
      781 caaatggaac agatgcaagt aagtatgttc aatttgaagg tagcgca
//
LOCUS       DAVDHZ010000101          692 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000101 DAVDHZ010000000
VERSION     DAVDHZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.103"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VUR46_002166"
     tRNA            complement(74..147)
                     /locus_tag="VUR46_002166"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VUR46_002167"
     tRNA            complement(157..242)
                     /locus_tag="VUR46_002167"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VUR46_002168"
     tRNA            complement(250..321)
                     /locus_tag="VUR46_002168"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VUR46_002169"
     tRNA            complement(344..416)
                     /locus_tag="VUR46_002169"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VUR46_002170"
     tRNA            complement(435..516)
                     /locus_tag="VUR46_002170"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VUR46_002171"
     tRNA            complement(522..594)
                     /locus_tag="VUR46_002171"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VUR46_002172"
     tRNA            complement(619..691)
                     /locus_tag="VUR46_002172"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVDHZ010000102          681 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000102 DAVDHZ010000000
VERSION     DAVDHZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..681
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.104"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(133..681)
                     /locus_tag="VUR46_002173"
                     /pseudo
     CDS             complement(133..681)
                     /locus_tag="VUR46_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          181 a          137 c          130 g          233 t
ORIGIN      
        1 tacggcaagg tgaagctgac gtggtttgaa gagattttcg aagaatatta atgatagata
       61 aagtgagcct gggacaaaat agttctcaat cacaaaaaag ctagagattt ccaattgtgg
      121 aactctagct ttttaatttt gagtcgttct cttgttgtat tttaggaggt tattgaccat
      181 aagtaccaat cccatgtcaa ttctcagttg acgcttgcct ctcagattac atctcttgta
      241 acccaaacaa gcctttatct gcccaaagac aggttccaca tcaatcttgc gttgagcgaa
      301 aatctgtcta ccttggggag ataaaagcgc ctgacattct ttagctttca agttttgata
      361 gccttcgttc atatacagtc ccttttgagg ggctgattca ggttcgtcgg cgtagtaaac
      421 cttgatttct tgttgaaagt ctgtctgtgt tttctgatgt ttggtatggt gaaaacgata
      481 ataccagcca tcaggatgtg tatagctatc ctccttgtca ttatagtgcc aattccctaa
      541 gtttttagct gactatttat agcctctctt ttgttcctta tcaaacatgg catatttaat
      601 cagatggttt acctcctttt catctaaacg aaggaggtta tcttcactta catatccagc
      661 atctgcgaca actgtcttca a
//
LOCUS       DAVDHZ010000103          607 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000103 DAVDHZ010000000
VERSION     DAVDHZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.105"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            1..607
                     /locus_tag="VUR46_002174"
                     /pseudo
     CDS             1..607
                     /locus_tag="VUR46_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          232 a          100 c          124 g          151 t
ORIGIN      
        1 tcctgattta aaacaagaaa tgattaataa agtctgacat gaaggctgga ctaaagatag
       61 agtttctctt gaatacggtc tcccaagtcg tacgatactt cttaactggc tagcacaata
      121 caggaaaaac gggtatacta ttgttgagaa aacaagaggg agagtacctg agagcggaga
      181 atgccatcct aaaaaagtta agagaactcc gattgaagga ggagaaagaa gaaagacaga
      241 aattgttcaa gaattaatga ctgaattttc gttagctctt cttctaaaag tcattaaact
      301 agctcgttgg acctactact atcacttgaa acagctagac aaaccagata aggaccaaga
      361 gcttaaagct gaaattcaat ccatttttat cgaacacaag ggaaattata cttatcgccg
      421 ggttcattta gaactaagaa atcgtggtta tctggtaaat cataaaagag ttcaaggctt
      481 gatgaaagta ctcaatttac aagctaagat gcgacagaaa cgaaaatatt cttctcataa
      541 aggagacgtt ggtaagaagg cagagaatct cattcaaggc caatttgaag gctctaaaac
      601 aatggaa
//
LOCUS       DAVDHZ010000104          595 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000104 DAVDHZ010000000
VERSION     DAVDHZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.106"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(12..491)
                     /locus_tag="VUR46_002175"
     CDS             complement(12..491)
                     /locus_tag="VUR46_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET5457502.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          160 a          141 c           80 g          214 t
ORIGIN      
        1 tgcatgactt cctagtgggt acggatagta aactccttaa acacaatgcg taagtctctt
       61 aatactcttt gacgccctcg aaatcgttca ttgcttaaga cgcgttctag ttcttcttgt
      121 ttctctttac tttgtttgtt tctataatct cttagtgttt catgaaagag ataataatca
      181 tctagccaga gacccccctc acttatacga tgactgatct ctcccacttc ttcatagggt
      241 tctttatcgt atctacgctt ctgactttcc tgcttacgga tatagtctaa aattcgattt
      301 cgaaacttgg ttttgaaata tttccttaaa cgtggaatat cgtctaccag tccttcttct
      361 ctactaatca attcatgtaa gcagagcatg ccttcttggt cccaatccga caattcccat
      421 aaatgaaggt aatattcatt tctacactta tacacagtcc cttggacttc ttcatacaat
      481 tctttaatca taattttccc ctttctagat acagtctaac agattagaaa acacatttgt
      541 tacattttct ccattctgtt ccctttagct cctaaactgc acaaaaaaaa gaggc
//
LOCUS       DAVDHZ010000105          538 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000105 DAVDHZ010000000
VERSION     DAVDHZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.107"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(110..193)
                     /locus_tag="VUR46_002176"
     tRNA            complement(110..193)
                     /locus_tag="VUR46_002176"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(157..159),aa:Leu,seq:caa)
     gene            complement(203..274)
                     /locus_tag="VUR46_002177"
     tRNA            complement(203..274)
                     /locus_tag="VUR46_002177"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(240..242),aa:Gln,seq:ttg)
     gene            complement(288..360)
                     /locus_tag="VUR46_002178"
     tRNA            complement(288..360)
                     /locus_tag="VUR46_002178"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:His,seq:gtg)
     gene            complement(375..445)
                     /locus_tag="VUR46_002179"
     tRNA            complement(375..445)
                     /locus_tag="VUR46_002179"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(411..413),aa:Trp,seq:cca)
     gene            complement(450..530)
                     /locus_tag="VUR46_002180"
     tRNA            complement(450..530)
                     /locus_tag="VUR46_002180"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(494..496),aa:Tyr,seq:gta)
BASE COUNT          150 a          136 c          117 g          135 t
ORIGIN      
        1 ttttaatcat gtgcttttat atgaaattag taattattag taacaattcc aagaaatttc
       61 ttatggcata acaaaaagac aaggtttcta acccttgtct tttctactat accggcggcc
      121 ggggtcgaac cggcacgtcc ttgcggacac tggattttga gtccagcgcg tctgccaatt
      181 ccgccacgcc ggcaaatagt aactggggta gctggattcg aaccaacgca tgagggagtc
      241 aaagtccctt gccttaccgc ttggctatac cccaataata taaaataggc gagtgatggg
      301 gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt aaccacttca ccacacccgc
      361 cataattcta ttaacacggg cagtaggaat tgaacccaca ctgaaggttt tggagacctt
      421 agttctacct ttaaactatg cccgtaaaat ggaaggggag ggattcgaac ccccgaaccc
      481 gaaggagcgg atttacagtc cgccgcgttt agcctcttcg ctacccttcc aaaatata
//
LOCUS       DAVDHZ010000106          473 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000106 DAVDHZ010000000
VERSION     DAVDHZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.108"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>473
                     /locus_tag="VUR46_002181"
     CDS             <1..>473
                     /locus_tag="VUR46_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET5457503.1"
                     /translation="VLTAAVMSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRP
                     STDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISD
                     IPFDGPIAGVQVGYVDGQIIINPSQEQAEQSLLELTVAGTKHAINMVESGAKELS"
BASE COUNT          130 a          100 c          111 g          132 t
ORIGIN      
        1 gtcttgactg ctgccgttat gtctaagaaa atggcaactg gggatttctt cccactccaa
       61 gtcaactacg aagaaaaaat gtatgcggct gggaagtttc ctggtggctt tatgaaacgt
      121 gaaggacgtc cttcaacaga tgcgaccttg acagcgcgtt tgattgaccg tccgattcgt
      181 cctatgtttg cggaaggttt ccgtaatgaa gtccaagtca tcaatacagt gctttcttat
      241 gatgaaaatg catctgcacc aatggctgct atgtttggtt catctttggc actgtctatt
      301 tcagatattc catttgacgg accaattgct ggggtacaag tgggatatgt agatggccaa
      361 atcatcatca acccaagtca agaacaagca gagcaatctc ttcttgaatt gacagtagct
      421 ggaaccaagc acgctatcaa catggtagag tctggtgcca aagaattgtc aga
//
LOCUS       DAVDHZ010000107          459 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000107 DAVDHZ010000000
VERSION     DAVDHZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.109"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>459
                     /locus_tag="VUR46_002182"
     CDS             <1..>459
                     /locus_tag="VUR46_002182"
                     /inference="COORDINATES: protein motif:HMM:NF019202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET5457504.1"
                     /translation="KNDIEADDKLTTEEKQAAKDKVDAAAQSAKDAVTAATTNDGVTQ
                     AQNDGTTAVNNVDTTPKAKPSAKAEIDAKVQDANNAIDQNQDLTDDERREAKKAVKDA
                     ADEAKANIDKATSAGELTTAKNNGLDKLNEPQDASVKQKAKDDIDTKATAK"
BASE COUNT          173 a           91 c          117 g           78 t
ORIGIN      
        1 aaaaatgaca tcgaagcaga cgacaagttg acgactgaag agaagcaagc agctaaggat
       61 aaggtagatg cggcagctca aagtgctaaa gatgcggtta ctgccgcaac taccaacgat
      121 ggtgtgactc aagctcagaa tgatggaact actgctgtta acaatgttga tacaacgcca
      181 aaagcgaaac catcagccaa ggcagaaatt gatgccaagg ttcaagatgc caacaatgcc
      241 attgaccaga atcaagatct gacggacgat gagcgtagag aggctaagaa agcagtgaag
      301 gacgcagctg atgaagctaa ggctaatatt gacaaggcga catctgcagg agagctcaca
      361 actgctaaga acaacggtct tgataagttg aatgagccac aagacgcaag cgttaaacaa
      421 aaagctaaag atgacattga tacgaaagct acggctaag
//
LOCUS       DAVDHZ010000108          458 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000108 DAVDHZ010000000
VERSION     DAVDHZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.110"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>458
                     /locus_tag="VUR46_002183"
     CDS             <1..>458
                     /locus_tag="VUR46_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET5457505.1"
                     /translation="REIRNLEKMIKEIDKAIEDMVETIPEYQCLTSIPGVGKVYAAGI
                     IAEIGQIERFKDHPQVAKFAGLNWREKQSGNSNSQHTSLVNRGNRYLRYYLVEAANSV
                     RRYDDEYKDFYKKKYHEVPKHQHKRAIVLTARKFVRLVVVLLRNHQLYTPP"
BASE COUNT          148 a          104 c          100 g          106 t
ORIGIN      
        1 agggaaattc gaaacctgga aaaaatgatc aaggaaattg ataaggccat tgaagatatg
       61 gtggaaacca ttcctgaata tcaatgcctg acctccatac ctggggtcgg taaggtctac
      121 gctgctggta tcattgccga aattggacaa atcgaacgct ttaaagacca tccccaggtc
      181 gcaaagtttg ctggtctgaa ttggagagaa aagcaatctg gtaactcaaa ctcacaacat
      241 acttcgcttg tgaatagggg caatcgttat ctgcgctact acctggttga agccgccaac
      301 tcggtaaggc gctatgatga cgaatacaag gatttctata agaagaaata ccatgaagta
      361 cctaaacacc aacacaaacg agccatcgta ctaaccgcta gaaaatttgt gcgtctggtg
      421 gttgtgctac tacgcaacca tcaactctat acgccacc
//
LOCUS       DAVDHZ010000109          457 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000109 DAVDHZ010000000
VERSION     DAVDHZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.111"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>457
                     /locus_tag="VUR46_002184"
     CDS             <1..>457
                     /locus_tag="VUR46_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET5457506.1"
                     /translation="VDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVTAVY
                     EEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVVDFL
                     PRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFP"
BASE COUNT          132 a           98 c          112 g          115 t
ORIGIN      
        1 acgtggatgc tgaattgcaa gctgaaatca ttgcagccta caacagtgac ctccaaaagg
       61 cagttcaagt agaagagaaa ttggcccgtg aagctgcgac tcaagtagtg aaagaccaag
      121 tgactgccgt ttacgaagaa aaatatgcgg accacgaaga atttgaccgt attatgcgtg
      181 atgtggctga aatcttggaa caaatggaac acgcagaagt gcgacgttta attacagaag
      241 acaaggtgcg tcctgatggt cgtaaggtcg atgaaatccg tcctttggat gcggttgtcg
      301 acttccttcc tcgtgtacat ggttcaggtc tctttactcg tgggcaaact caagctcttt
      361 cagtcttgac cttggctccg atgggagaaa ctcaaatcat tgatggtttg gatccagagt
      421 acaagaaacg ctttatgcac cactataact tccctca
//
LOCUS       DAVDHZ010000110          410 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000110 DAVDHZ010000000
VERSION     DAVDHZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.112"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>410
                     /locus_tag="VUR46_002185"
     CDS             <1..>410
                     /locus_tag="VUR46_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET5457507.1"
                     /translation="MLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVA
                     LDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLI
                     SKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTA"
BASE COUNT          148 a           94 c           81 g           87 t
ORIGIN      
        1 atgttgactc gtctcttact caaggcatct gacaaggcac catggtcaga taacggtgac
       61 gctaaaaatc cagccctatc tccactaggc gaaaacgtga agaccaaagg tcaatacttc
      121 tatcaagtag ccttagacgg aaatgtagct ggcaaagaaa aacaagcgct cattgaccag
      181 ttccgagcaa acggtactca aacttacagc gctacagtca atgtctatgg taacaaagac
      241 ggtaaaccag acttggacaa catcgtagca actaaaaaag tcactattaa cataaacggt
      301 ttaatttcta aagaaacagt tcaaaaagcc gttgcagaca acgttaaaga cagtatcgat
      361 gttccagcag cctatcttga aaaagccaag ggtgaaggtc cattcacagc
//
LOCUS       DAVDHZ010000111          334 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000111 DAVDHZ010000000
VERSION     DAVDHZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.113"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            complement(<1..>334)
                     /locus_tag="VUR46_002186"
     CDS             complement(<1..>334)
                     /locus_tag="VUR46_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HET5457508.1"
                     /translation="PNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQVQTMLEQAFKE
                     KHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMF
                     YGYEKSFRS"
BASE COUNT           91 a           64 c           69 g          110 t
ORIGIN      
        1 gatctaaagc tcttctcata accataaaac atctccgatt tcaaaatgcc aaagaaagat
       61 tccatcatgc cgttgtctgg gctgttgccc ttgcgtgaca tggatgcttg aattccctta
      121 ctctctagga accgatgata agaatcgtgt tggtattgcc agccttggtc actatggaga
      181 atcgtattct catagtgctt ctctttgaat gcctgttcca acattgtttg tacttgttct
      241 aagttgggtg aagtagaaag atgataagca atgatttcac tgttaaagcc atctaaaact
      301 ggtgataaat agagtttctg tgtgctattt ggaa
//
LOCUS       DAVDHZ010000112          330 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000112 DAVDHZ010000000
VERSION     DAVDHZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.114"
                     /strain="36"
                     /db_xref="taxon:1313"
BASE COUNT           92 a           65 c           63 g          110 t
ORIGIN      
        1 cttggtatct tgatgacttg aattttggtc tcatttctta ggaaaaaaga taagcttcct
       61 agcactcgtc gagtgcgacg tcaccttcct atttttctac agaaatgttc ggcaagccga
      121 accgtccaaa atatcttgtg taattgaaca cggccgaaaa gctgtgtaaa aaagataaac
      181 tgtcttgtct tcatcgaaga cttcgtcagt ttcctatttt tactttgctt ttgacgtcct
      241 tggtatcttg atctttgtag gcaaggcgta taatttcatc aatccaaagg ggattaaaat
      301 ggcaaaacaa gtgtttcaaa cgacttttgc
//
LOCUS       DAVDHZ010000113          243 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000113 DAVDHZ010000000
VERSION     DAVDHZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.denovo.115"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            <1..>243
                     /locus_tag="VUR46_002187"
     CDS             <1..>243
                     /locus_tag="VUR46_002187"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457509.1"
                     /translation="PPTNADKVTITYTNQAGAQQTVKLSKTGGNWSVTEGDGTVLSGN
                     QVVLPYKGLDRTQVIGTSATAGSDKYMSEVASQDYTV"
BASE COUNT           81 a           57 c           63 g           42 t
ORIGIN      
        1 ccaccaacca atgcggacaa agtgaccatc acgtatacca accaagctgg agcacaacag
       61 accgtgaaat tgtctaagac aggtggcaac tggagtgtaa cagagggaga cggaaccgtt
      121 ctttcaggta atcaggttgt tctaccgtac aagggacttg atcgcacaca agttataggc
      181 acaagtgcca cagcaggaag cgacaagtac atgagtgaag tcgcaagtca ggactacaca
      241 gtg
//
LOCUS       DAVDHZ010000114        27947 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.guided.027, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000114 DAVDHZ010000000
VERSION     DAVDHZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.guided.027"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            122..205
                     /locus_tag="VUR46_002188"
     CDS             122..205
                     /locus_tag="VUR46_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HET5457510.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            330..1067
                     /gene="erm(B)"
                     /locus_tag="VUR46_002189"
     CDS             330..1067
                     /gene="erm(B)"
                     /locus_tag="VUR46_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HET5457511.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(1324..2571)
                     /locus_tag="VUR46_002190"
     CDS             complement(1324..2571)
                     /locus_tag="VUR46_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5457512.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            2751..2972
                     /locus_tag="VUR46_002191"
     CDS             2751..2972
                     /locus_tag="VUR46_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457513.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            3089..3586
                     /locus_tag="VUR46_002192"
     CDS             3089..3586
                     /locus_tag="VUR46_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET5457514.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            3561..4067
                     /locus_tag="VUR46_002193"
     CDS             3561..4067
                     /locus_tag="VUR46_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET5457515.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            4051..6498
                     /locus_tag="VUR46_002194"
     CDS             4051..6498
                     /locus_tag="VUR46_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5457516.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            6501..8678
                     /locus_tag="VUR46_002195"
     CDS             6501..8678
                     /locus_tag="VUR46_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET5457517.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            8675..9676
                     /locus_tag="VUR46_002196"
     CDS             8675..9676
                     /locus_tag="VUR46_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET5457518.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            9673..10608
                     /locus_tag="VUR46_002197"
     CDS             9673..10608
                     /locus_tag="VUR46_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET5457519.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            10853..10969
                     /locus_tag="VUR46_002198"
     CDS             10853..10969
                     /locus_tag="VUR46_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET5457520.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            10985..12904
                     /gene="tet(M)"
                     /locus_tag="VUR46_002199"
     CDS             10985..12904
                     /gene="tet(M)"
                     /locus_tag="VUR46_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET5457521.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            13023..13190
                     /locus_tag="VUR46_002200"
     CDS             13023..13190
                     /locus_tag="VUR46_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET5457522.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(13250..13603)
                     /locus_tag="VUR46_002201"
     CDS             complement(13250..13603)
                     /locus_tag="VUR46_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5457523.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            14108..14530
                     /locus_tag="VUR46_002202"
     CDS             14108..14530
                     /locus_tag="VUR46_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET5457524.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            14527..14757
                     /locus_tag="VUR46_002203"
     CDS             14527..14757
                     /locus_tag="VUR46_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5457525.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            15218..15421
                     /locus_tag="VUR46_002204"
     CDS             15218..15421
                     /locus_tag="VUR46_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET5457526.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            15503..16720
                     /locus_tag="VUR46_002205"
     CDS             15503..16720
                     /locus_tag="VUR46_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5457527.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            16990..17580
                     /locus_tag="VUR46_002206"
     CDS             16990..17580
                     /locus_tag="VUR46_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET5457528.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVAEGKIDA
                     EEKGLYRLPDIYLDEWFVLQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEVERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNKIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            17580..18416
                     /locus_tag="VUR46_002207"
     CDS             17580..18416
                     /locus_tag="VUR46_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET5457529.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIHIFEEILCSNTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AEKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQIIREIMQQ
                     IF"
     gene            18699..18998
                     /locus_tag="VUR46_002208"
     CDS             18699..18998
                     /locus_tag="VUR46_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457530.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            18988..19476
                     /locus_tag="VUR46_002209"
     CDS             18988..19476
                     /locus_tag="VUR46_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457531.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            19476..21353
                     /locus_tag="VUR46_002210"
     CDS             19476..21353
                     /locus_tag="VUR46_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET5457532.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSL
                     K"
     gene            21374..21616
                     /locus_tag="VUR46_002211"
     CDS             21374..21616
                     /locus_tag="VUR46_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5457533.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            21633..22487
                     /locus_tag="VUR46_002212"
     CDS             21633..22487
                     /locus_tag="VUR46_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET5457534.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            22541..22900
                     /locus_tag="VUR46_002213"
     CDS             22541..22900
                     /locus_tag="VUR46_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET5457535.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            22893..25208
                     /locus_tag="VUR46_002214"
                     /pseudo
     CDS             22893..25208
                     /locus_tag="VUR46_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241830.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            25220..27925
                     /locus_tag="VUR46_002215"
     CDS             25220..27925
                     /locus_tag="VUR46_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5457536.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSFLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQESKQKSNFFFQGKSLEELKAKKE
                     VKAAKENLKSTKQAYKYKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     FRKLKKQGLSSVQNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELQKPV
                     HLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGQSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDAVVSL
                     DGDNIILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYDFLKSQGVSPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTSDGSTRYTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPADYGHVAFVGARRF"
BASE COUNT         9275 a         4769 c         5689 g         8214 t
ORIGIN      
        1 taagacttag aagcaaactt aagagtgtgt tgatagtgca gtatcttaaa attttgtgta
       61 taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg agggattcgt
      121 catgttggta ttccaaatgc gtaatgtaga taaaacatct actgttttga aacagactaa
      181 aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt gactaatctt
      241 atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct gtatttgttt
      301 atagatgtaa tcacttcagg agagattaca tgaacaaaaa tataaaatat tctcaaaact
      361 ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta aaagaaaccg
      421 ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg gctaaaataa
      481 gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg tcagaaaaat
      541 taaaactgaa tactcgtgtc actttaattc accaagatat tctacagttt caattcccta
      601 acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca caaattatta
      661 aaaaagtggt ttttgaaagc cgtgcgtctg acatctatct gattgttgaa gaaggattct
      721 acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact caagtctcga
      781 ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa gtaaacagtg
      841 tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg aagctatata
      901 cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact aaaaatcagt
      961 ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccattact tatgagcaag
     1021 tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc tatgagtcgc
     1081 ttttttaaat ttggaaagtt acacgttact aaagggaatg gagataaatt attagatata
     1141 ctactgacag cttccaagaa gctaaagagg tccctagcgc ctacggggaa tttgtatcga
     1201 taaggggtac aaattcccac taagcgctcg ggaccccttg taggaaaatg tcctaagtgg
     1261 gatatctgtc aactggtatg gttgactaaa aatacttcct acgaaaatgt agggggtatt
     1321 tttttacgaa aaaatacaat cgattcttaa aaagaaaaat ttttgattgg caaaaccata
     1381 acaagttcgt tttagggttt tgattttgcg attgatgcct tctaaaggac cattagagta
     1441 ttcaaattta gcgctattta agacatattt tctgttttga cgaagggttt gaatagcagt
     1501 atccatttct gtattggttt tttggtagtc taagatggtt gactctagta attcactatt
     1561 gcgctcgttt agggctttcg tgatatcttg gtaagtttgg tatacttcag cgaacttgga
     1621 aaatttacta gtaatgagat caacagcatt ttggcgagtc atatattgtt taacgccgcg
     1681 aagaaaaact acttcttcag ggtgaagatc ttcagctttt ttatggaata gcttccaatg
     1741 tgacttcata attttatatt cttggctctg tttatcaagt tgctttagga tagagatacg
     1801 acaattgtcc aaagcgcgac cagctaattg tacaaggtgg aagcgatcaa taatgatatt
     1861 ggcattaggg aaaaggcgat agataaaact ttgatattga gcatttaaat caattacaac
     1921 tgattgaacg cattcgcgtt cggcttttga ataacgactt tcaaaataat caacaatggt
     1981 aggtgataga cgatcctgta actttgtgac aatttggtgg gtttcagcgt cacaacagat
     2041 aaaggacatc acagacttaa ttgaacgaaa ctcgtcaaaa catagatgct taggcaactt
     2101 agccacacga tagtgtggtt ccatgcgctc taagattgtt cgacgaacac tgctaggaga
     2161 gcagtgacac atttcagcaa taagctgacc agataagcct ttacgagcta aaagcatgat
     2221 ttgatttttg agatcactgg ataaggtttg attttctttg gttaaattag taatagcacc
     2281 aaaagtagta tggcatgatt tacatttata gcgttgttta cgaagctcta gttcatatct
     2341 tctcccattt aaacttgcca gtcgtacatg agttttgcga aagccatcct tattaactgt
     2401 gggaaagcca cagttacgac aacgattaat cggataagaa agagtagctg ttattagcgt
     2461 tatatactct ttaacagaat cgttgttgtg ttcagcttct tcaacagaaa taattttaat
     2521 atttttatct ttaattccaa gaatatttag gatagaatca ttatgggaca tttgtttaac
     2581 cttctttcat gatttttgtg gtgaattgat tgtataacga ggggacagca aatgtcctct
     2641 tttttgtata aaaaaatctg gcatggaatc tctatccata ccagaaagtg tataccccaa
     2701 aaaaataact caaatacaaa ttcattgaat atagagagga gaacattttt atgaattttg
     2761 gacaaaacct ttataactgg tttctatcaa acgctcaatc actggtgctt ttagcaatcg
     2821 ttgtgattgg cttgtatctt ggcttcaagc gtgagtttag caaactgatt ggctttttaa
     2881 ttattgcgat tattgcggtt ggcttagtct tcaacgctgc tggagtaaaa gacattttac
     2941 tagagctatt caatcgcatt attggtgctt aaataaaacc gttcttttgt ggaatataag
     3001 tggttttctt atgttccgca aaggaatggt acaccaaacg aagtgcggta gggatttttg
     3061 aatctctaca aagaaaggac gtgaatatat ggacgatatg caagtctata ttgcgaattt
     3121 aggcaaatac aatgagggcg aattggtcgg tgcgtggttt acctttccca ttgactttga
     3181 ggaagtcaaa gagaaaatcg gcttgaatga tgaatatgag gaatacgcca ttcatgacta
     3241 cgagttaccc tttacggttg acgaatacac ttccattggc gaactcaatc gactatggga
     3301 aatggtatcg gaattacccg aagaattaca atcggagcta tctgctctgc tcactcattt
     3361 ttcaagcatt gaagaactaa gcgaacatca agaggatatt atcattcatt ccgattgtga
     3421 tgatatgtat gacgtggcac gctactacat tgaagaaacg ggtgctttag gcgaagtacc
     3481 agctagtctt caaaactata ttgattatca agcctatggt cgggatttag acctttcagg
     3541 aacgtttatc tcaaccaatc atgggatttt tgaaatcgtc tattaaatct gtcggtacat
     3601 tactactggc agattttcta ttttacgggg tggctcaatc agctacccct attttttatg
     3661 aaaggattga ttacatgaag aaaatacgaa gctataccag tatctggtct gtggaaaagg
     3721 tactgtattc tatcaatgat tttagacttc cgtttcccat aacctttacg caaatgacat
     3781 ggtttgtcgt gtcactcttt gcagtgatga tacttggcaa cttgccccct ctttccatga
     3841 tagagggagc atttctcaaa tactttggga ttcctgtggc tttcacatgg tttatgtcta
     3901 caaaaacttt tgatggtaaa aagccttatg gatttttgaa gtctgtcatt gcttatgcac
     3961 tgcgaccaaa gctgacctat gcaggaaaaa aagtaacgct tggcagaaac cagccacaag
     4021 aagccattac agcagttagg agtgaatttt atggcatatc caattaaata cattgaaaac
     4081 aatctcgtct ggaataaaga cggggaatgt tatgcttact atgagcttgt tccttacaat
     4141 tactcatttc taagtccaga acagaaaata caagtgcatg attctttcag acagcttatc
     4201 gcacaaaatc gtgatggcaa aattcatgct ttacaaatca gtacagaatc cagcatacgt
     4261 tctgcacaag agcgttccaa aaatgaagtc actggcaagc tcaaagcggt tgcctatgac
     4321 aaaatcgacc aacagacaga cgctttaata tccatgattg gcgaaaatca agtggactac
     4381 cgtttcttta tcggttttaa gttgcttctc aacgatcagg agttttctat gaaaagtctt
     4441 accgttgaag caaaaaatgc ttttactgat tttgtctatg atgtgaacca taagctgatg
     4501 ggcgattttg ttagtatgag taatgatgaa atcctgcgtt ttcagaagat ggaaaagctt
     4561 ttagaaaata aaatctcccg tcgtttcaaa atccgaagat tagataagga cgacttcggc
     4621 tatctgattg aacaccttta cggacagaca ggcactgcct atgaagagta tgagtaccat
     4681 ctatcaaaga aaaagctgga taatgaaacg ctgattaaat actatgactt gattaagcct
     4741 actcgctgtc tggtggaaga aaaacagcga tatttgaaaa tccagcagga agatgaaacc
     4801 gtctatgtag cttactttac cattaacagc attgtcggag aactggactt cccgtcctct
     4861 gaaatcttct actaccagca acagcaattt acattcccga ttgatacgtc aatgaatgtg
     4921 gaaattgtag cgaatcgtaa agccctatct actgtccgca ataaaaagaa agaactgaaa
     4981 gacttggata accacgcttg gcaaagtgat aatgaaacca gctccaatgt ggcggaagct
     5041 ctggaaagtg tgaatgagct ggaaaccaat ttagaccaaa gcaaggaatc tatgtacaag
     5101 ctgtcttatg tggtaagggt atcagcaaat gatcttgacg aactcaaacg tcgttgtaat
     5161 gaagtgaaag atttttatga cgatttaagc gtaaaactgg tacgaccatt tggggatatg
     5221 ctcggcttac atgaagaatt tttacctgcc agcaagcgtt atatgaatga ttatattcaa
     5281 tacgtgacct ctgatttcct cgctggttta ggttttggtg ctactcaaat gctgggggaa
     5341 aatgagggga tttatgttgg ctacagctta gatactggac gcaatgtcta tctgaaacct
     5401 gctcttgcca gtcaaggggt taagggttca gtaaccaatg cgttagcgtc ggcttttgtt
     5461 ggttcgctgg gtggtggtaa atcctttgcg aataacctta tcgtctatta tgcggtgctt
     5521 tatggggcac aagcagtgat tgtagaccca aaagcagaac gtggcagatg gaaagaaacc
     5581 ttgccagaga tttcccatga aatcaatatc gtcactctga cttctgatga gaaaaacaaa
     5641 ggcttacttg acccttatgt gattatgaaa aatcccaaag attctgaatc actggctatt
     5701 gatattctga cattccttac ggggatttcc tctcgtgatg gggaacgctt cccaatcctt
     5761 agaaaagcca ttcgtgcagt aaccaatagt gaagtacgag ggttgatgaa agtgattgag
     5821 gaattacggg ttgagaatac gccactaagt accagtatag ccgaccatat cgaaagtttt
     5881 acagactatg actttgcaca tttattattc agtaatggtt atgtggagca gtctatcagc
     5941 ttagaaaaac aactgaacat tatacaggtt gcggacttgg tacttcccga caaggaaact
     6001 tcctttgagg aatataccac tatggagctt ttatccgttg ctatgctgat tgtcattagt
     6061 acctttgctt tagactttat ccatacagac cgaagcattt tcaagattgt agatttagac
     6121 gaagcatgga gctttttaca ggtagcacaa ggaaaaacac tatctatgaa gctggttcgg
     6181 gctggtcgtg ctatgaacgc tggggtatat ttcgtgaccc aaaatacaga cgacctctta
     6241 gatgaaaaac tgaaaaataa cctcggctta aaatttgcat ttcgttccac tgaccttaac
     6301 gagattaaaa agaccttagc cttttttggt gtagacccag aggacgaaaa caatcagaag
     6361 cgattgcgtg atttggaaaa cgggcaatgc cttatcagtg atttatatgg tcgtgtcggt
     6421 gtgatacagt tccaccctgt atttgaagaa ctgctccatg cctttgatac cagaccacct
     6481 gtgcgaaaag aggtgtaaat gtgaaaccat caatagtaaa cagaataaaa tcaaactgga
     6541 cgctgaaacg tctaggtaaa gtggcaatga cagtggcttt cacacttgtg attgccattt
     6601 ttcttttagc catgctggga acggtggttc aagctgcggg cttggtagat gatacggtca
     6661 atgtggcaaa tgaatacagc cgatacccac ttgaaaacta tcaactggat ttttatgtgg
     6721 ataatagctg gggctggctt ccgtggaact ggtcggacgg gattggaaaa caggtcatgt
     6781 atggactata tgccattacc aattttattt ggacaatcag tttgtatgtt tccaatgcga
     6841 caggttactt agtacaggaa gcctattcct tagacttcat ttccgctaca gcagattcca
     6901 ttggtaagaa tatgcagacc ttagctggtg tgagtgcaaa cggattttca acagagggtt
     6961 tctatgttgg attcctctta ctcttgattt tggttcttgg ggtttatgtt gcctatacgg
     7021 gactgataaa gagagaaacc acaaaggcaa ttcatgccat tatgaatttt gtgctggtgt
     7081 ttatcctatc ggcttccttt attgcctacg ctcccgacta cattaaaaaa atcaatgact
     7141 tttcatcaga catcagtaat gccagtttat cacttggcac gaagattgtc atgccccatt
     7201 ccgatagtca aggcaaggac agcgtggact taatcagaga tagcctgttt tccatacagg
     7261 ttcagcaacc gtggctactg cttcaataca acagttcaga cattgaaagt atcggtattg
     7321 accgtgtgga aagcctgctc tccaccagcc cagattccaa caatggcgaa gacagagaaa
     7381 aaattgttgc ggaagaaatt gaagacagaa gcaataccaa tctaaccatt acaaagacca
     7441 ttaaccgttt aggtacagtc ttcttcctat ttgtcttcaa tattgggatt tccatatttg
     7501 tattcctatt aacaggaatc atgattttct cgcaggtact ttttatcatc tatgctatgt
     7561 ttctgcctgt gagctttatt ttaagcatga ttccatcatt tgatggtatg tcaaaacgag
     7621 ccataacaaa gctctttaat accattttga cacgagctgg aatcacattg attattacga
     7681 cagcatttag tatttcaacc atgctctata ccttatcggc tggttatccg ttctttttga
     7741 ttgcttttct acagattgtg acctttgcag gaatctactt caagctgggc gatttaatga
     7801 gtatgttttc tctacagagt aacgattctc aaagtgtggg aagtcgtgtg atgagaaaac
     7861 ctcgtatgct tatgcacgct cacatgcacc gtctacagcg gaaacttgga cgttccatga
     7921 ctactctagg ggctgggtct gccattgtta caggtaaaaa aggacagtcg ggttcgggga
     7981 gttctgcaag gacacaagca gatcactccc gaccagacgg aaaggaaaaa tcaacacttg
     8041 gaaaacgtat cggtcaaacc atcggtacag tagctgatac caaagacaga atggtagaca
     8101 ctgctagtgg tttgaaagaa caggttaaag atttgccgac caatgcaaga tatgcagtat
     8161 atcaaggaaa atccaaagta aaagagaatg tccgtgattt aaccagtagt atttctcaaa
     8221 ccaaagcgga cagagccagt ggacgcaagg aacagcagga acaaaggcga aaaaccattg
     8281 cgaagcgtcg ctctgaaatg gaacaggtca aacagaaaaa acagcctgct tcttctgttc
     8341 atgaaagacc gactacaaga caagaacaat atcatgatga acagacctca aaacagtcta
     8401 atattcagac ttcatataag gaatctcaac aagccaaaca agagcgtcca gcagttaagt
     8461 ccgatttttc aagtccaaaa gtggaacgcc aaggcaatac cgttcaagaa aaaaccgttc
     8521 aaaagccagc aacttcaacc actacagcag atagaacttc acaacgtcca atcacaaaag
     8581 aacgtccgtc tactgttcaa agagtaccac tacaaaatac aagaagtaga ccaccaatca
     8641 aaaccgccac cattaagaaa gtcggtaaga aaccatgaag ttgaaaactt tagtgattgg
     8701 tggttctgga ttattcttga tggtcttctc actgcttctg tttgttgcca ttttattttc
     8761 agatgaacag gacagcggaa tttccaatat tcattatgga ggtgtgaatg tttccgcaga
     8821 agtgctggct cataagccta tggtagaaaa atatgccaaa gaatatggcg ttgaagaata
     8881 tgtcaacata cttcttgcga ttatacaggt ggaatcgggc ggtactgcgg aagatgttat
     8941 gcagtcctcg gaatccctcg gtcttccacc taattcattg agtacagaag aatccattaa
     9001 gcaaggtgtg aagtatttca gtgaattatt agccagtagc gaaaggctca gtgtagattt
     9061 agaatcggtt atccagtcct acaattatgg tggtggtttc ttagggtatg tggctaatcg
     9121 tggaaataaa tatacctttg aactggctca aagtttctca aaagagtatt caggtggcga
     9181 aaaagtgtct taccccaatc ccatagccat acctatcaat gggggctggc gatacaacta
     9241 tggcaatatg ttttatgtgc aactggtaac gcagtatctt gtcacaacag agtttgatga
     9301 tgatacggta caagccatca tggacgaagc actgaaatat gagggctggc gatacgttta
     9361 cggtggagct tccccgacta cttcttttga ttgtagcgga ctgacacaat ggacgtatgg
     9421 aaaagctgga attaacttac cacgaaccgc acaacagcaa tatgatgtga cccagcatat
     9481 cccactatcg gaagcacaag ctggcgattt ggttttcttt cattctacct ataacgctgg
     9541 ctcttatatt actcatgttg ggatatacct tggcaataac cgtatgtttc atgcaggcga
     9601 cccaatcggt tatgccgact taacaagccc ctactggcaa cagcatttag tgggagcagg
     9661 acgaatcaaa caatgagaaa ggaagattta atgatgaaat ttagaaaaaa tcagaataaa
     9721 gaaaaacaga taccaaagga aaagaaacct cgtgtctact ataaggtcaa tcctcataaa
     9781 aaggttgtga ttgccttgtg ggtactttta gggcttagtt tcagctttgc gatattcaag
     9841 cactttacag ctatagatac tcatactatt cacgaaacaa ctatcataga aaaggaatac
     9901 gttgatactc atcatgtaga aaattttgta gagaactttg cgaaagtcta ctattcatgg
     9961 gagcaatccg ataagtccat tgataatcga atggaaagtc taaaaggcta tctgacagat
    10021 gaacttcaag ctctcaatgt tgatacagta cgcaaagata ttcctgtatc gtcttctgta
    10081 agaggatttc agatatggac ggtagagcca actggcgaca atgagtttaa tgtaacctac
    10141 agtgtagacc agctcattac agagggagaa aatacaaaga ccgtccactc tgcttatata
    10201 gtgagtgtct atgtagatgg ttctggaaat atggtactgg ttaagaatcc gaccattacc
    10261 aacataccta agaaatcaag ttataaacca aaagccattg aaagtgaggg gacggttgat
    10321 tccattacaa ccaatgaaat caatgagttt ttaacgacgt tcttcaagct ctatcctaca
    10381 gcgacagcca gtgaactttc ctactatgtg aatgacggga tattaaaacc aatcggaaaa
    10441 gagtacatct ttcaagaact ggtaaatcct attcacaatc gtaaggataa tcaagtcacg
    10501 gtatcgctga cagtggagta tatcgaccag cagaccaaag caacgcaggt atctcaattt
    10561 gatttggtac ttgaaaagaa cgggagtaat tggaagattg taaaataaca aatattggta
    10621 catgattaca gatactttgt aatcatgtac tctttttgat aaaaaattgg agattccttt
    10681 acaaatatgc tcttatgtgc tattatttaa gtgactattt aaaaggagtt aataaatatg
    10741 cggcaaggta ttcttaaata aactgtcaat ttgatagcgg aaacaaataa ttagatgtcc
    10801 ttttttagga gggcttagtt ttttgtaccc agtttaagaa tacctttatc atgtgattct
    10861 aaagtatcca gagaatatct gtatgctttg tatacctatg gttatgcata aaaatcccag
    10921 tgataaaagt atttatcact gggattttta tgcccttttg ggtttttgaa tggaggaaaa
    10981 tcacatgaaa attattaata ttggagtttt agctcatgtt gatgcaggaa aaactacctt
    11041 aacagaaagc ttattatata acagtggagc gattacagaa ttaggaagcg tggacaaagg
    11101 tacaacgagg acggataata cgcttttaga acgtcagaga ggaattacaa ttcagacagg
    11161 aataacctct tttcagtggg aaaatacgaa ggtgaacatc atagacacgc caggacatat
    11221 ggatttctta gcagaagtat atcgttcatt atcagtttta gatggggcaa ttctactgat
    11281 ttctgcaaaa gatggcgtac aagcacaaac tcgtatatta tttcatgcac ttaggaaaat
    11341 ggggattccc acaatctttt ttatcaataa gattgaccaa aatggaattg atttatcaac
    11401 ggtttatcag gatattaaag agaaactttc tgccgaaatt gtaatcaaac agaaggtaga
    11461 actgtatcct aatatgtgtg tgacgaactt taccgaatct gaacaatggg atacggtaat
    11521 agagggaaac gatgaccttt tagagaaata tatgtccggt aaatcattag aagcattgga
    11581 actcgaacaa gaggaaagca taagatttca taattgttcc ctgttccctg tttatcacgg
    11641 aagtgcaaaa aacaatatag ggattgataa ccttatagaa gtgattacga ataaatttta
    11701 ttcatcaaca catcgaggtc cgtctgaact ttgcggaaat gttttcaaaa ttgagtattc
    11761 ggaaaaaaga cagcgtcttg catatatacg tctttatagt ggcgtactgc atttgcgaga
    11821 ttcggttaga atatcggaaa aggaaaaaat aaaaattaca gaaatgtata cttcaataaa
    11881 tggtgaatta tgtaaaatcg ataaggctta ttccggggaa attgttattt tgcagaatga
    11941 gtttttgaag ttaaatagtg ttcttggaga tacaaagcta ttgccacaga gagagagaat
    12001 tgaaaatccc ctccctctgc tgcaaacgac tgttgaaccg agcaaacctc aacaaaggga
    12061 aatgttactt gatgcacttt tagaaatctc cgacagtgac ccgcttctgc gatattatgt
    12121 ggattctgcg acacatgaaa tcatactttc tttcttaggg aaagtacaaa tggaagtgac
    12181 ttgtgctctg ctgcaagaaa agtatcatgt ggagatagaa ataaaagagc ctacagtcat
    12241 ttatatggaa agaccgttaa aaaaagcaga gtataccatt cacatcgaag ttccaccgaa
    12301 tcctttctgg gcttccattg gtctatctgt agcacagctt ccattaggga gcggagtaca
    12361 gtatgagagc tcggtttctc ttggatactt aaatcaatcg tttcaaaatg cagttatgga
    12421 ggggatacgc tatggctgtg aacaaggatt gtatggttgg aatgtgacgg actgtaaaat
    12481 ctgttttaag tatggcttat actatagccc tgttagtacc ccagcagatt ttcggatgct
    12541 tgctcctatt gtattggaac aagtcttaaa aaaagctgga acagaattgt tagagccata
    12601 tcttagtttt aaaatttatg cgccacagga atatctttca cgagcataca acgatgctcc
    12661 taaatattgt gcgaacatcg tagacactca attgaaaaat aatgaggtca ttcttagtgg
    12721 agaaatccct gctcggtgta ttcaagaata tcgtagtgat ttaactttct ttacaaatgg
    12781 acgtagtgtt tgtttaacag agttaaaagg gtaccatgtt actaccggtg aacctgtttg
    12841 ccagccccgt cgtccaaata gtcggataga taaagtacga tatatgttca ataaaataac
    12901 ttagtgtatt ttatgttgtt atataaatat ggtttcttgt taaataagat gaaatatttt
    12961 ttaataaaga tttgaattaa agtgtaaagg aggagatagt tattataaac tacaagtgga
    13021 tattgtgtcc tgtatgtgga aataaaacac gattaaagat aagggaagat actgaattaa
    13081 aaaaattccc cctctattgt ccgaaatgca gacaagaaaa tttaattgaa ataaagcagt
    13141 tcaaagtaac tgtgattaca gagccagacg caaagacgca gagccgataa aatgagatta
    13201 atacaatctc attttatcgg ctctttccgt tatgtatgga ttcttttaat tagtcttcga
    13261 tgtttcttgc ttcgttgata ccgctggcta aagattccat taaggatagt tctttgtctg
    13321 taaagctatc catgtatttc tctatctgta atcgtcgggt gctttttacc aagttattag
    13381 caggtaagaa aaattcatca acggaaacat gaagtaacga tacaaggtca taaagaactt
    13441 gtatgctggg gtgttgccct ttattttcaa tattagttaa gtaccgtggg tcaatttcaa
    13501 tcaatgctcc cacttgttca cgagttaaac ctcgtttcaa tcgagcttct ttaatggcta
    13561 aaccaaaggc tctaaaatca tatttatctt cttttttacg catagtagac cacctctata
    13621 cattttattg tccctactga attaaaaaca ggtatagaaa aacgtgttat atggtttata
    13681 ggtttatatt taataaaaag cactactaaa cgccaataaa aaaaaccgtt atatggtagt
    13741 gctatttacg ctgttaaaat attgtatatt acttccaaat ggcggtttgt tggaggtcaa
    13801 cgtcgccatg aagtacatca tatacaataa atttccttac attgggttct tgtcaaaaaa
    13861 agtcgtctat ctgcaataga taagtacgtc caccaatgtg gttttataaa tcatatagat
    13921 agaataacag aagcatgtaa acagagaaat aaatctgttt atatgctttt ttggctattc
    13981 agaacttttt tacaaagttt atttatcagt aatgcaacaa atcccccttt cacattggga
    14041 ctaagagtga aaggagataa acgagcaagg ctcacttcct ttcctagaca gaaagggggt
    14101 gagaaacatg aaaccatctt cttttcagac cacaatagaa aatcagtttg actatatctg
    14161 taaacgtgct atggaagacg agcgaaagaa ttatatgctt tatctttcaa ggattgcaaa
    14221 gcgtgaggtg tccttttcgg atgttggcga ttatcttgtt agccagtttg cgacaacaga
    14281 taactattca actgactttc agatttttac actcaatggg ttatcagtag gcgttgaaaa
    14341 tgatttgttg agtgaagcat tacgtgagtt gccagacaag aaacgtgaaa ttctactgct
    14401 gttttacttt atggacatga gcgattcaga aattgcagac ctgttgaaat tgaaccgttc
    14461 tactgtctat cggcatagaa ccagtggact agccttaatt aaaaagttta tggaggaatt
    14521 tgaagaatga aaacacaata tcctatgatt ccctttcctc tcattgtaaa ggcaacagat
    14581 ggcgataccg aagcgattaa ccagattcta catcattaca gagggtacat aacgaagcgt
    14641 tccctacgac ttatgaaaga tgaatatggc aatcaaagta tggtcgttga tgaagtctta
    14701 cgtggaagaa tggaaaccag actgattaca aagattttgt catttgaaat taagtaatat
    14761 cctctctcct ttcgtggaag cgtgctaaac cattccacgc ttcccgaaca gggaggtttg
    14821 ttattccacc aaagcatatt gagctttcaa tgtgttttga taggctaacg agccattgtt
    14881 ctttgaaaac tgaataaaag taatcgaata cgtttcgata agaaaagagc caacggaact
    14941 aaccgccatg acctatctta taaagatagc gagcgattca tgttagtgat ccgagaagca
    15001 atctttagca ggattgcctg caacgacatt cttatcgtga taatgatact cccatacagt
    15061 caatagtccg agcgtgataa aaccgtcgca ggcaatgagt atggctacat gagaaccatg
    15121 caggggtgga actcccgtga gctttgctaa agctgttcga ttgctggtaa aacaactttt
    15181 atgaaatcca aataagtgat ttggaaagga ggattttatg aagcagactg acattcctat
    15241 ttgggaacgt tataccctaa ccattgaaga agcgtcaaaa tattttcgta ttggcgaaaa
    15301 caagctacga cgcttggcag aggaaaataa aaatgcaaat tggctgatta tgaatggcaa
    15361 tcgtattcag attaaacgaa aacaatttga aaaaattata gatacattgg acgcaatcta
    15421 gcgtcgccaa agggtcttgt atatgataaa atagtattaa gtcgtatcaa ggctctttcc
    15481 ataaaggaaa ggagcaaatg ccatgtcaga aaaaagacgt gacaataaag gtcgaatctt
    15541 aaagactgga gagagccaac gaaaagacgg aagatactta tacaaatata tagattcatt
    15601 tggagaaccg caatttgttt actcgtggaa acttgtggct acagaccgag taccagcagg
    15661 aaagcgtgat tgtatctcac ttagagagaa aatcgcagag ttacagaaag acattcatga
    15721 tggtattgat gttgtaggaa agaaaatgac actctgccag ctttacgcaa aacagaacgc
    15781 tcaaagacca aaggttagaa aaaacactga aactggacgc aaatatctta tggatatttt
    15841 gaagaaagac aagttaggtg taagaagtat tgacagtatt aagccatcag acgctaaaga
    15901 atgggctatt agaatgagtg aaaatggtta tgcttatcaa accatcaata actacaaacg
    15961 ttctttaaag gcttcattct atattgctat acaagatgat tgtgttcgga agaatccatt
    16021 tgactttcaa ctgaaagcag ttcttgatga tgatactgtc cctaagaccg tactaacaga
    16081 agaacaggaa gaaaaactgt tagcctttgc aaaagctgat aaaacctaca gcaaaaatta
    16141 tgatgaaatt ctgatactct taaaaacagg tcttcgtatt tcagagtttg gtggtttgac
    16201 acttccagat ttagattttg agaatcgtct tgtcaatata gaccatcagc tattgagaga
    16261 tactgaaatt gggtactaca ttgaaacacc aaagaccaaa agtggcgaac gtcaagttcc
    16321 tatggttgaa gaagcctatc aagcatttaa gcgagtgtta gcgaatcgaa agaatgataa
    16381 gcgtgttgag attgatggat atagtgattt cctctttctt aatagaaaga actatccaaa
    16441 agtggcaagt gattacaacg gcatgatgaa aggtcttgtt aagaaataca ataagtataa
    16501 cgaggataaa ttgccacaca tcactccaca tagtttgcga catacattct gtaccaacta
    16561 tgcaaatgca ggaatgaatc caaaggcatt acagtacatt atgggacatg ctaatatagc
    16621 catgacgctg aactattacg cacatgcaac attcgattct gcaatggcag aaatgaaacg
    16681 cttgaataaa gagaagcaac aggagcgtct tgttgcttag tagtacaaat gaatttacta
    16741 cttatttacc acttctgaca gctaagacat gaggaaatat gcaaagaaac gtgaagtatc
    16801 ttcctacagt aaaaatactc gaaagcacat agaataaggc tttacgagca tttaagaaaa
    16861 tataaaaaga taattagaaa tttatacttt gtttatttat aaaaaaacta aatgaattga
    16921 ttttaaagaa ataaaatgct aacatatata gtagatgtta gtattttatt tctaagaaag
    16981 gagaatgata tggttgataa aagagagaaa ctgatgaact ctttcaatca gtatggtttt
    17041 ttaactttta aacaagtaat agatgaaaat ttacactaca aaaccttatt aaaaatggtt
    17101 gcagaaggaa aaatcgatgc tgaagaaaaa gggttatatc gcttacctga tatttattta
    17161 gatgagtggt ttgtccttca gtatcgattt ccaaagggaa tcttttcttt ggagacagca
    17221 ctttggttac atggtttatc tttgactatc ccttttaaca tgacgatgag ttttccttat
    17281 ggtacgaata ccaaaaacat taaggaagca gatatatgtc ctattatctt acgctctcac
    17341 tatagtgaag gaattattga aatagagcgc cttcctggtc aatttattaa agtttatgaa
    17401 gttgagcgag ttttggttga atgtctaaga ccagttcatc aggtggatct tcaaattatt
    17461 gcaccagcgt ttaaaaaata ttttcaacaa aataaaattc atttacacaa attattttat
    17521 tatgcccagc tatttaaagt aactgataag ttacaatctt atacggaggt actatcttaa
    17581 tgttttcaaa tgcgaatagc tttaaagcaa aaatcaaaaa catttcaaaa gataagggaa
    17641 ttccagctca acaagtacaa caacattatt taattgagca agtgttaaag ctgatttcta
    17701 ctagttctta tagagattcc ttcattgtaa aaggagggta tctaataggt caaatgattg
    17761 gactagataa gcgaaccaca atggatttag atgtcactct gaagggaacc gaaatgagca
    17821 gagaaaattt gattcatatc tttgaagaga ttctttgttc taatactgat ggattttcat
    17881 tttcagtaga taagctagaa cctattcgtc aagatgatga atatggagga ttttcattaa
    17941 aattaaatgc aacttttgat acattaaaag aggttgtttt tattgatatt actactggtg
    18001 ataaaatcac accaagagaa attacttatt caatgacttc tatctttact aatgaaagca
    18061 tcaagatatg gacatataat ctagagactg tacttgctga aaagttagaa acaatcatca
    18121 gtaggggact agcttcgacg cgtccacgtg atcgatatga tcttttcacc ttgtataaac
    18181 ttagaaaaga agagattaat cttgaagtat taaaaaatgc acttgagaat acggcagaaa
    18241 aacgtaaaag taaagatact atttataatt gggaagaaca agtgagagga attgaaattt
    18301 ctgattatca gaaagagcta tggattcgtt atcaacgcca atttaagtat gctaaagata
    18361 tctcatttga taactctgtt cagatcatta gggaaattat gcaacaaata ttttagtaca
    18421 aaagtaactc attagtaaag cagtgagttg ctttttttat tccaataact ccaaaaatgt
    18481 gataaaaatt tcaactactc ttatctataa taaagctacc tgttctttga aaattgaatc
    18541 cactccgtct tgattagcgt gcctgtgtaa gtagggactg agagtatttc cctgtgaagg
    18601 gcaactggca caagacgtgt gtgagaattt tctaacagac acggagttta tcgttaccag
    18661 acttaaacga tgcgacaaac tagataaagg agttaatcat gaaggtagta aacttgtatg
    18721 atttgaaaca aatgggaaat aaaggtggtt gtaccatcca attgattcat cactttcctt
    18781 ttggtatggg cttaggacat ctcaaaaaag actacattga atttaaacgt gttggtatcg
    18841 ttgatgggaa ggcagtagaa gtcactcttc gagaacctta ttcgagagat ctactgcagg
    18901 ttgtcaagtc gattaagcaa cgtcagaaat tgatagctta tcgttataaa gaaggaaagc
    18961 tgctatttgt gaagaaggag gcatcagatg tcctctgaac aacaggaacg aatggcagtt
    19021 caatatgcgg agcgtagtct tttatttact gtcaaaagtc tcttaaaaat tctagaatgg
    19081 tctagacgtc aggctttagc acaggattcc gcctataaga taggggtgca gaaattagaa
    19141 gaattgctac aatctcctta ttcgattgat acgattaatc tgaaaaaaga ttttttagac
    19201 aaaccaattg atatagagaa atttaaagct tttttagaaa aagaagagat tcctttagcc
    19261 atcgcttggc aaggggattc tctacatttc tacacgaaag accgttcgat tctggacaat
    19321 catttagacc atctgttaga aaaaatggtt aatgatccgg agaaattagc tgattttacc
    19381 atggataagt cattagacga tgcaattgat gaggcgaaat cccaaattac ctttagacaa
    19441 gaaggggccg tcaaacagaa agagatggtg agatgatgta cagtggaaag aaattcctac
    19501 tattttcact gttaggtatc ttactaggct atctttttca tcgtttgacg cttttgtatg
    19561 attcctatac tggaaataca ttagataaat ggactcatct tctgatggaa ggtcaagatg
    19621 aagttcttca gtcgccatgg aatgtttcct ttactggaaa atccagtgct ttttttctac
    19681 taggctttgt gatgatgttg ctggtttatc tttatttaga gactggcaaa aaacaatacc
    19741 gagaaggggt agaatacggg agcgcccgtt ttggaactct aaaagaaaag aagctctttt
    19801 acggtaagga attttctcat gatacgatct tagctcaaga tgttcgtttg acattattag
    19861 ataaaaaacc accccaatat gatagaaata agaatattgc ggtgatcgga ggttcaggaa
    19921 gtgggaagac atttcgcttt gtgaaaccta atcttattca gatgaatagt tctaatattg
    19981 tagtggatcc taaagatcac ttggccgaaa aaacaggcaa actcttttta gaacatggct
    20041 atcaagtaaa ggtgctagat ttagtcaata tgaagaactc agatggcttc aatccttttc
    20101 gctatataga gacagaaaat gatttgaatc gcatgctgac ggtttatttt aataacacca
    20161 aaggctctgg ctcccgaagt gacccatttt gggatgaagc ttctatgact ttggttcgag
    20221 ctttagcctc ttacttggtc gatttctata atccacccaa aacaagagaa cagctcattg
    20281 aagagagtcg tttgagtcaa aaagaatacc agaacttgtt gaaacgtcaa aaaaaagaag
    20341 tggaagagcg aaaaaaacga ggacgttatc caagttttgc tgaaatctca aaactcatta
    20401 aacacttatc taagggtgaa aaccaagaaa aaagtgtctt agaaattcta tttgaaaatt
    20461 atgctaaaaa gtatggcact gaaaatttta ccatgcgaaa ttgggcagat ttccaaaatt
    20521 ataaggataa gactctggat tctgttatag ctgtaaccac tgctaaattt gccctcttca
    20581 atattcaaag tgtcatggat ttgaccaaaa gagataccct tgatatgaag acatggggcc
    20641 aggaaaaatc aatggtttac ttagttatcc cagataacga tagtaccttt cgctttcttt
    20701 cagccctctt tttttcaacc gtatttcaaa ccctaacaag acaagcagat attgatttta
    20761 agggtcaatt gcctcttcat gtgagagtct acttagatga gttcgcaaat ataggagaaa
    20821 tcccagattt tgctgaacaa acctcaacag tccgttctcg aaatatgagt ctcgttccca
    20881 ttcttcaaaa tattgcccaa cttcaagggc tctataaaga aaaagaagct tggaaaacca
    20941 ttttggggaa ctgtgatagc ttagtctact taggtgggaa tgatgaagat acctttaaat
    21001 ttatgagtgg cttactcggt aaacaaacca ttgatgttcg aaatactagt cgttcctttg
    21061 gccagacagg ttcaggatcc ctttctcatc aaaagattgc tcgtgattta atgacacctg
    21121 atgaggtcgg aaatatgaaa cggcatgaat gcttggttcg aattgccaat atgcctgtct
    21181 ttaaaagcaa aaaatacaat tccactaagc atccaaactg gaaataccta gccaatcaag
    21241 aaaccgatga acggtggtgg aactatcaaa tcaatccttt gaatcaaaga caagaaaatc
    21301 atcttgaagg ccttagaatt cgtgatttaa cttttgaatc tagtttaaaa taaaaataga
    21361 aaagaggaaa tagatgatta cgcattttaa aggttttgtt tatggagtag acgcaagtgc
    21421 tatgtttgca caagctatgt ctttgttaca gaagggtttg attgcggttg gtgcctttct
    21481 cgttgttgtg gggattgtca atcttgcaac caacattaaa gatggtggac caggtgttcg
    21541 gaatgccatt ctggaaattg tcggtggtgt tatggtaggg gctgctggag cctttgtaac
    21601 tcaaatttca atttaggagg ataaacaatg acatgaatct tagtttagtc tcaccctttg
    21661 tttaccttgc atctgaaaaa atatcagctg aaaatttatt tgaagggttt aatgtagatt
    21721 tacaatctac ggtagatctg attaaatccc tatctagcta caatccaaca gtttggactt
    21781 atatgtctag tattactaaa agtgtcatgc agcctcttgg agttgcgatt ttatcagttg
    21841 ttctcatctt agaattttcg aagatggcaa agaaaattgc taactcagga ggagcgatga
    21901 cctttgaagc attagcgccg atgttgatta gttatatcat ggtcgcagtc gtgattacca
    21961 atactaccgt tattgtagaa gccatcatcg ggattgcgag tcacgccatt gaacaagtgg
    22021 cctcaattgt ggctcacggt ggggcaaagt atgataccat ctctggatta aaaggttcag
    22081 gatttattgg ccggatgatt gtgggctttt tcgccctcct catttggcta gttcggatag
    22141 taagtgcagc catggttaac cttttggtat ctattcgatt tattcaactc taccttatga
    22201 ttccatttgc ccctcttacg attccaacat ttttaagtga tgaatggaag tctattggta
    22261 ttggctattt aaaaaatatt atggtttatg cggtacaagg ggttctcatt tttctgattg
    22321 tttctcttgt tcctttattt gaatctgctg ggaaaatagc tgtttcaaat ggtgcaggag
    22381 tcttgcaatc acttgcgatt atgtttggta gtttggtaca agctatctta ctgattattg
    22441 ccctcgttgg ttctcaacgt acggctcgct caatcttagg tatgtaatta gataaaggct
    22501 aggaagtgat tgcttcttag cctttttaga aaggaaagtc atgaatacac gtgtctttaa
    22561 agacatctca aaataccaac acagggcttg gttaggtttc accacaagac aaatcatctt
    22621 tgttttacca gcctttattg tcacaattat tgttttgggc ttgaatctct ttttctggca
    22681 atttggagat tggtttgttt acggttttgt gtttgctttt accatccccc tcatgctttt
    22741 tggagtctat aaacccaatg atttatattt tgaacattat ttgaaatacc gtcttcattt
    22801 tgaactaacg gttcccctac gcacaattac aggaaagaaa ggacctgaac atgaaaagaa
    22861 aatcaaatac attaaagaaa caaaaaactt caatgactaa tcagaaagaa gtagttaaag
    22921 gaaaaaaaga ggaagtgtta ccatcgacgg ctaatactct ttcctatcaa gccctgtatc
    22981 aaaatggtct gatgcaggta aaagaagatt atttctcaca aagctattta cttggtgatg
    23041 tcaattacca gactgttggt ttagaagata agggcgcaat cattgagaag tattctgatt
    23101 tgattaactc cctagacgac caaaccaact tccaattgac tatctttaat aaaagattga
    23161 atttagaaaa gtttagacaa agtgttttgt atgaggaaaa agaagatggg tatgatagct
    23221 atcgtaaaga attgaatcgg atgatgaatc agaatttaga cagtggtgaa aataactttt
    23281 cagctgtgaa actgattagc tttggtagaa aggattctaa tcccaaacaa gcctatcgtt
    23341 ccttgtctca aattggagaa tatttcaaga gtggtttctc agaaattgat gctcgatttg
    23401 aatctttggc tggagaagaa cgggtgaact tgctggcaga tatgcttaga ggagaacacc
    23461 atcttccttt ttcttaccgt gatttaacga gatctggtca gacaactcgt cacttcatag
    23521 cacctaatct cttggatttt aaaaacaaga attacctaca aatcaatgac cgcttattgc
    23581 agattgtcta tgtcagagac tacggtatgg aattaggaga tcagtttatt tgagacctca
    23641 tgcaaggaga tttggaattg attgtgagcc tccatgctca aagttcgacc aaggcggatg
    23701 ctatgaagaa actacgaaca aagaagacct tgatggaatc ccaaaagatt ggggaacaac
    23761 aaaaacttgc tcgtacaggt atctatttgg aaaaagtagg tcatgtatta gaaagcaata
    23821 tcgatgaagc tgaggaactc ttaaaaacca tgaccgagac aggagataaa ctatttcaaa
    23881 cagtattctt gattggtgtt tttggtcagg atgaagaaga acttaaacaa gctctagata
    23941 cgattcaaca agtggccggc tcaaatgacc taatgattga taaactacca tatatgcaag
    24001 aagcagcctt taatagtttg ctgccatttg gttgtgattt tttagaggga gtatcacgga
    24061 gtttattaac atccaatata gcagtgaact ctccatggac ttcagtagac ttacaagacc
    24121 gtagtggaaa atattacggt atcaatcaaa tctcaagcaa tattattacc attgatcgca
    24181 gcctattaaa tacaccgtct ggtctgattt tagggacatc tggagctggg aaagggatgg
    24241 caaccaagca tgaaattatc acgacccaaa tcaaggaatc tggtgaaaat actgaaatta
    24301 tcatcgtgga tccagaagca gaatacagtg tcattggacg agcttttggt ggagaaatga
    24361 ttgatattgc gcccgattcc caaacttatc tcaatgtcct tgatttgtct gaggaaaata
    24421 tggatgaaga tcctgtaaag gtaaaatcag aatttctttt atcctttatc ggcaagttat
    24481 tggatagaaa aatggatgga agagaaaaat cgattatcga ccgagtcaca agactcacct
    24541 atcagtcatt taaagagcct tctttggaag aatgggtctt tgtcttgagc caacaaccag
    24601 aagaagaagc gcagaatttg gcacttgata tggaactgta tgtcgaaggt tctcttgata
    24661 ttttttctca taagaccaat attcagacag gatctaattt cttgatttat aacgttaaga
    24721 agttaggaga tgagctgaaa caaatcgccc ttatggttgt ttttgatcag atatggaatc
    24781 gtgtcgttcg gaatcaaaaa ttagggaaga agacctggat ttattttgat gaaatgcagc
    24841 ttctcttatt agataaatat gccagtgatt tcttctttaa attgtggagt cgtgtcagaa
    24901 aatatggagc cagtctgact ggaataactc aaaacgtcga aaccttattg ttagatccaa
    24961 atggtagacg gattattgca aatagtgaat ttatgattct tctcaagcaa gcaaaaaatg
    25021 accgagaaga actggttcaa ctcttaggct tgtcaaaaga actcgaaaaa tacctagtca
    25081 atccagaaaa aggagcagga ctgataaaag ctggttcagt tgtcgtacca tttaaaaata
    25141 agattcctca aggtactcaa ttgtttgata ttatgagtac ggatcctgat aaaatggctt
    25201 ctaattaagg ggaaggtaaa tgaaggataa aagagaaatc atacgtgccc gaaaagcatt
    25261 tagaagaagt ctaaaagatg agaagaaatt cttgaaacaa ggaaagaagg aggtgaggaa
    25321 acagaaaaaa gattccgctg tactggatga aaaagcatgg aaaaaagaga taaaagaaaa
    25381 gctagaggag atgagagaag cttcaaagga gagagtaaaa caagcaaatg aagactacaa
    25441 tcatattctt caaaatagtc ctccatcttt tttgaatcgt aaagaattaa gagacagacg
    25501 attacctcat gctaggaaac gattgaaaat agccaagaag caatttagag aagccaaggt
    25561 agaagcaaaa gaagaaagaa aagagagtcg taaagaaaga aaaaccaatc aaaaatttct
    25621 ctacggtcag gaatcgaaac aaaaatctaa ttttttcttt caagggaaga gtttagaaga
    25681 attaaaagct aagaaagaag tcaaggctgc taaagaaaat ttaaaatcta ctaaacaagc
    25741 ctataagtac aaaaaagtca gtaggaaagc caaaactttt ctttatgtcc ttggacgtga
    25801 aggtggagag ttagcttcag aaaatgaaga tttagaaggc tatcgcacac ttcaagagac
    25861 cattagaaaa gggaaacgct acagtcggct ttcttataat cttggaaaag ctagtgtcaa
    25921 aacaggacaa gcaacaggtc gttttaccaa gaaaagactg accaacacaa aagagcgata
    25981 ccatcatttt aaggatggaa aaggatggaa actagcaaaa gataacccaa gttcctttaa
    26041 gaatcggttt cgaaaattaa agaaacaagg tctttcaagt gtccaaaata tctatcaaaa
    26101 actaaaagca gccttttcct tctttacatt tgcggctgga aatcctgcaa catggatagt
    26161 tggaggaata gtctttcttc ttttacttat gatgagcttc ttcttaggat tttcatctgc
    26221 tagtttgatt caacaagatg aatttgaatt aacaaaagct tatacccacc taacttggga
    26281 agatgcagaa catactcgca caaatgacaa aggaattacc tattacacaa aagttgatga
    26341 tgtgatgggg tatatgaact ttaaattcca tgactatgag ttacagaaac cagttcactt
    26401 atttagttca gaaacttaca aggattatct gtctactttg tggcatgatt taaacgatgg
    26461 tgatgatttg aaatccatgc aagacctcta tgaaactcct aagtataaac tatcgaaaga
    26521 cgatcaagag gaaataaagg aactaaaaga agaaggtgtg tatgcttcca tgcaggaatt
    26581 agacaatcca tttgagggac aaagcaacga agatagtcta accatgactt atcgttatgg
    26641 atactatgat ttagatggga aacctactct tcaggagtac atcctactag aagcaaaggc
    26701 tcaccaaacg attgtcgcac caatggatgc agttgtatct ctagatggtg acaatattat
    26761 tctcactaac ggaaaaggag agaatgagag tcgattaacc ttgtattcta ttcataatgg
    26821 ccgtgcgatt gaggggacaa gagtcctaac gggtgatatt attggtgaaa caccagacga
    26881 tacaggtttg aaagtttcct atcaaaagta taagaacaag aaagaaaaat tggtgtatgt
    26941 caatccgcaa ttttattttc caaaagtcat tcaacttcag accactatct tacctgccat
    27001 tggtcagttt ggtggggatg agtttgaacg agcaaaacat atttatgatt ttttgaaatc
    27061 tcaaggcgta agtccccaag ccattgcggc tattttagga aattggtctg tagagtcttc
    27121 tattaatcca aaacgagctg aaggagatta tttatctcct ccagttggcg ctaccgattc
    27181 ctcatgggat gatgaaagct ggttagcgat tggaggtcca gccatttata gtggtgctta
    27241 tcctaatatt cttcatagag gtttggggtt agggcaatgg acggatactt cagatggttc
    27301 aacacgttat acagctttat tgaattatgc acatagcaaa aataagaagt ggtatgattt
    27361 agacctccaa cttgatttta tgcttcatgg ggatagtcct tactaccaaa gttggttaaa
    27421 agatttcttt aaaaatacgg gcagtgcagc caatctcgcc caactcttcc tcacctattg
    27481 ggagggaaat tctggtgaca aattactgga aagacaaacc agagcaacgg aatggtatta
    27541 ccaaattgaa aaaggcttca gccaaacaaa tggaggacag gcaaaaagtg acccacaatc
    27601 ccttgaaggg gttcgtgggg acttgtatga tcattctgtt cctggtggtg gagatggtat
    27661 ggcctatgcc tatggacaat gtacatgggg tgttgcggct cgtatgaatc aattaggctt
    27721 aaaattaaaa ggaagtaatg gagagaagat ttcaatcatt aataccatgg gaaatggtca
    27781 ggactgggtt gcgacagctt caagtcttgg tggggaaact ggctctacac caagagcagg
    27841 tgctattgtt tcttttgtgg gaggtacaca tggcacacca gcagactatg gtcatgtagc
    27901 ttttgtaggt gcgagacgtt tctaactgaa aaggttagac acgttct
//
LOCUS       DAVDHZ010000115         2319 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 36
            SAMEA3145689-rid19732083.guided.087, whole genome shotgun sequence.
ACCESSION   DAVDHZ010000115 DAVDHZ010000000
VERSION     DAVDHZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145689
            Sequence Read Archive: ERR755385
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930060.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930060.1
            Genome Coverage       :: 242x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 06:38:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,218
            CDSs (total)                      :: 2,182
            Genes (coding)                    :: 2,022
            CDSs (with protein)               :: 2,022
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 30
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 160
            CDSs (without protein)            :: 160
            Pseudo Genes (ambiguous residues) :: 0 of 160
            Pseudo Genes (frameshifted)       :: 77 of 160
            Pseudo Genes (incomplete)         :: 64 of 160
            Pseudo Genes (internal stop)      :: 54 of 160
            Pseudo Genes (multiple problems)  :: 30 of 160
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2319
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145689-rid19732083.guided.087"
                     /strain="36"
                     /db_xref="taxon:1313"
     gene            251..1045
                     /locus_tag="VUR46_002216"
                     /note="aph(3')-IIIa"
     CDS             251..1045
                     /locus_tag="VUR46_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HET5457537.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1321..1893
                     /locus_tag="VUR46_002217"
     CDS             1321..1893
                     /locus_tag="VUR46_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HET5457538.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVILIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            2228..>2319
                     /locus_tag="VUR46_002218"
     CDS             2228..>2319
                     /locus_tag="VUR46_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HET5457539.1"
                     /translation="MGNLGAQKEKRNDTPISAKKDIMGDKTVRVR"
BASE COUNT          795 a          357 c          530 g          637 t
ORIGIN      
        1 taagacttag aagcaaactt aagagtgtgt tgatagtgca ttatcttaaa attttgtata
       61 ataggagtgg tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca
      121 actttgaaaa agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg
      181 agttcgtctt gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag
      241 gaaataataa atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata
      301 ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga
      361 aaatgaaaac ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt
      421 ggaacgggaa aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct
      481 gcactttgaa cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct
      541 ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga
      601 gtgcatcagg ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga
      661 cagccgctta gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga
      721 aaactgggaa gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac
      781 ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt
      841 tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa
      901 gtggtatgac attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta
      961 tgtcgagcta ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta
     1021 tattttactg gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac
     1081 aagcttttta gacatctaat cttttctgaa gtacatccgc aactgtccat actctgatgt
     1141 tttatatctt ttctaaaagt tcgctagata gagttctata ttagagatgt aaagagtttt
     1201 ggtgaagagg tttgtgagta tggcttttat aaccagggtg caatgagaag cactaacagc
     1261 agctagctta agaacgcata ggatatactt tttatggaag tcacagagga ggaataaaat
     1321 ttgaacagga ttaacagagt aacctctatt cttattcagc tgcaatcaaa aaaaataatt
     1381 cctgccaaag aaattgcaca gcgatttaat ataagcttaa ggacagttta cagagatatc
     1441 cggacacttg aagaagccgg aataccaatt ggatctgagg ccggaaaagg atattttctt
     1501 gtagagggct tcctacttcc gccggtaatg tttacagcgg cggaagtggg tgcattgatt
     1561 acagcaggga aatttttaaa ttgccatgga gatgaatcat ttataaagga ttttgattca
     1621 gctatgtata aaatcaaatc tattttgaag catggtgaaa aaaactatgc acaggagttg
     1681 gagaacagta ttaacgtgta cagcacatct ggacagaaaa atacattggc ggataacgtt
     1741 attgcagcaa ttcagactgc aatctgcaat aaaagggtaa tattaattca atatcctgca
     1801 tcaggagggc aagaaccgga aagcagaatg atagagccta tatcactggg gttttatgaa
     1861 cagaactggt acttaatcgg ttttgcaggc taagaaatga atataggaat tttcgtgtgg
     1921 atcggattaa aagcatttgc atagaagaag agctctgtca aagccatgat ggctctttgg
     1981 aacaaatatt aaaacaaatg ctttcatata aaaaactata tgccctacaa tgccgttgta
     2041 aaaattgggg aaaagggata tattgatttt atatctttct caaaataaac ataaaagccc
     2101 tttaaagagg gcttttatat attaatcaca aatcacttat cacaaatcac ttatcacaaa
     2161 tcacaagtga tttgtgattg ttgatgataa aataagaata agaagaaata gaaagaagtg
     2221 agtgattgtg ggaaatttag gcgcacaaaa agaaaaacga aatgatacac caatcagtgc
     2281 aaaaaaagat ataatgggag ataagacggt tcgtgttcg
//
